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34 results on '"BRIX, AMY E."'

5. Contributors

Author

Adams, E. Terence, primary, Adler, Rick, additional, Alden, Carl L., additional, Bartholomew, Phillip M., additional, Basu, Joydeep, additional, Beasley, Val R., additional, Berridge, Brian R., additional, Bertram, Timothy A., additional, Bhang, Hyo-eun, additional, Black, Hugh E., additional, Bolon, Brad, additional, Boorman, Gary A., additional, Bounous, Denise I., additional, Boyce, Rogely Waite, additional, Bracken, William M., additional, Brix, Amy E., additional, Brown, Danielle, additional, Butt, Mark T., additional, Cantor, Glenn H., additional, Car, Bruce D., additional, Castranova, Vincent, additional, Cattley, Russell C., additional, Chan, Curtis, additional, Chapin, Robert E., additional, Cohen, Samuel M., additional, Colegate, Steve, additional, Cook, Daniel, additional, Cooke, Paul S., additional, Crabbs, Torrie A., additional, Creasy, Dianne M., additional, Crissman, James W., additional, Cullen, John M., additional, Danilenko, Dimitry M., additional, Davis, Barbara, additional, Davis, Myrtle A., additional, Davis, T. Zane, additional, DeLellis, Ronald A., additional, Denslow, Nancy D., additional, Diegel, Kelly L., additional, Dorman, David C., additional, Dubielzig, Richard R., additional, Durham, Stephen K., additional, Eldridge, Sandy, additional, Elmore, Susan A., additional, Everitt, Jeffrey I., additional, Fenton, Suzanne, additional, Ferguson, Duncan C., additional, Field, Reuel, additional, Foley, George L., additional, Foster, William R., additional, Frantz, Jerry D., additional, Gabrielson, Kathy, additional, Gad, Shayne C., additional, Galbreath, Elizabeth J., additional, Gardner, Dale R., additional, Garman, Robert H., additional, Gill, Santokh, additional, Glerup, Peter, additional, Goad, Dale L., additional, Pecquet Goad, Mary Elizabeth, additional, Grand, Nanna, additional, Green, Benjamin T., additional, Gropp, Kathryn E., additional, Gundersen, Hans Jørgen G., additional, Gunson, Diane, additional, Gupta, Ramesh C., additional, Gwaltney-Brant, Sharon M., additional, Hall, Jeffery O., additional, Halpern, Wendy, additional, Hard, Gordon C., additional, Hardisty, Jerry F., additional, Harkema, Jack R., additional, Harvey, Philip W., additional, Haschek, Wanda M., additional, Heinz-Taheny, Kathleen, additional, Herbert, Ronald A., additional, Herman, Eugene, additional, Hoenerhoff, Mark, additional, Hubbs, Ann, additional, Hutto, David, additional, Janovitz, Evan B., additional, Khan, Kanwar Nasir M., additional, Keenan, Kevin P., additional, Kerlin, Roy L., additional, Kreeger, John M., additional, Krishnan, Kannan, additional, Kuper, C. Frieke, additional, Lee, Stephen T., additional, Lehman-McKeeman, Lois D., additional, Li, Xiantang, additional, Lombardini, Eric D., additional, Louden, Calvert, additional, Ludlow, John W., additional, Malarkey, David E., additional, Mann, Peter C., additional, Maronpot, Robert R., additional, McDorman, Kevin S., additional, Melanson, Mark A., additional, Mercer, Robert, additional, Mirabile, Rosanna, additional, Moch, Ronald W., additional, Morrison, James P., additional, Morton, Daniel, additional, Morton, Laura Dill, additional, Muthupalani, Sureshkumar, additional, Nikula, Kristen J., additional, Ochoa, Ricardo, additional, Pacheco-Thompson, Michelle E., additional, Pulido, Olga M., additional, Panter, Kip E., additional, Parker, George A., additional, Porter, Dale W., additional, Patterson, Douglas Reid, additional, Pfister, James A., additional, Pinkert, Carl A., additional, Ramaiah, Lila, additional, Rao, Deepa B., additional, Robertson, Donald G., additional, Rojko, Jennifer, additional, Rosol, Thomas J., additional, Rousseaux, Colin G., additional, Rudmann, Daniel G., additional, Ruehl-Fehlert, Christine, additional, Sargent, Linda, additional, Satterwhite, Christina M., additional, Schafer, Kenneth A., additional, Solter, Philip F., additional, Sills, Robert C., additional, Simon, Liz, additional, Skydsgaard, Mikala, additional, Smith, Graham S., additional, Sriram, Krishnan, additional, Stegelmeier, Bryan L., additional, Sullivan, John M., additional, Sutcliffe, Catherine, additional, Swenberg, James A., additional, Sysa-Shah, Polina, additional, Teixeira, Leandro, additional, Tsuchiya, Noriko, additional, Vahle, John L., additional, Van Vleet, John F., additional, Varela, Aurore, additional, Voss, Kenneth A., additional, Walker, Robin M., additional, Wallig, Matthew A., additional, Walter, Gail L., additional, Welch, Kevin D., additional, White, Paul, additional, Winkelmann, Christopher T., additional, Wojcinski, Zbigniew W., additional, and Wolf, Jeffrey C., additional

Published
2013
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6. Nomenclature

Author

Rao, Deepa B., primary, Herbert, Ronald A., additional, and Brix, Amy E., additional

Published
2013
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21. Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure

Author

Dunnick, June K., primary, Shockley, Keith R., additional, Morgan, Daniel L., additional, Travlos, Gregory S., additional, Gerrish, Kevin, additional, Ton, Thai-Vu T., additional, Wilson, Ralph, additional, Brar, Sukhdev S., additional, Brix, Amy E., additional, Waidyanatha, Suramya, additional, Mutlu, Esra, additional, and Pandiri, Arun Kumar R., additional

Published
2019
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24. Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure.

Author

Dunnick, June K., Shockley, Keith R., Morgan, Daniel L., Travlos, Gregory S., Gerrish, Kevin, Ton, Thai-Vu T., Wilson, Ralph, Brar, Sukhdev S., Brix, Amy E., Waidyanatha, Suramya, Mutlu, Esra, and Pandiri, Arun Kumar R.

Subjects
POLYBROMINATED diphenyl ethers, ATP-binding cassette transporters, RATS, CONFIDENCE intervals, ETHERS, TOXAPHENE, CARCINOGENICITY
Abstract

Human exposure to pentabromodiphenyl ether (PBDE) mixture (DE-71) and its PBDE-47 congener can occur both in utero and during lactation. Here, we tested the hypothesis that PBDE-induced neonatal hepatic transcriptomic alterations in Wistar Han rat pups can inform on potential toxicity and carcinogenicity after longer term PBDE exposures. Wistar Han rat dams were exposed to either DE-71 or PBDE-47 daily from gestation day (GD 6) through postnatal day 4 (PND 4). Total plasma thyroxine (T4) was decreased in PND 4 pups. In liver, transcripts for CYPs and conjugation enzymes, Nrf2, and ABC transporters were upregulated. In general, the hepatic transcriptomic alterations after exposure to DE-71 or PBDE-47 were similar and provided early indicators of oxidative stress and metabolic alterations, key characteristics of toxicity processes. The transcriptional benchmark dose lower confidence limits of the most sensitive biological processes were lower for PBDE-47 than for the PBDE mixture. Neonatal rat liver transcriptomic data provide early indicators on molecular pathway alterations that may lead to toxicity and/or carcinogenicity if the exposures continue for longer durations. These early toxicogenomic indicators may be used to help prioritize chemicals for a more complete toxicity and cancer risk evaluation. [ABSTRACT FROM AUTHOR]

Published
2020
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34. Chronic Energy Restriction Versus Energy Cycling and Mammary Tumor Promotion

Author

Harris, Steven R., Brix, Amy E., Broderson, J. Roger, and Bunce, Opal R.

Abstract

Chronic energy restriction significantly inhibits mammary tumor promotion in rodents. The present work studied the effect of short-term, intermittent energy restriction or energy cycling on mammary tumor promotion since this feeding paradigm mimics the dieting habits of humans. Female Sprague-Dawley rats were given 7,12-dimethylbenz[a]anthracene (DMBA) at 50 days of age (5 mg lg). One week later, rats were randomly divided into three dietary groups. One group was fed ad libitumthroughout the study (AL), another (ER) was fed 40% fewer calories than the AL group, and a third, energy-cycled group (EC) was fed in repeated cycles of 2 days of feeding at a level comparable to that of AL rats followed by 2 days of 40% energy restriction. At 10 weeks post-DMBA, the mammary tumor incidences in the AL and EC groups were the same, but incidence in the ER group was significantly lower. A second experiment examined serum levels of three hormones thought to play a role in mammary tumorigenesis. After 12 or 24 days on diet, ER rats had lower insulin levels compared with the other groups. Serum insulin levels in AL and EC rats were the same. After 24 days on diet, estradiol levels were significantly lower and cortlcosterone levels higher in the ER and EC groups compared with the AL group. Although energy cycling is a type of energy restriction that lowers overall weight gain and energy intake, it does not inhibit mammary tumor promotion as does chronic energy restriction. These data also suggest that feed efficiency and serum insulin levels correlate with susceptibility to mammary tumor promotion.

Published
1995
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