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1. Salvage Treatment for Invasive Aspergillosis and Mucormycosis: Challenges, Recommendations and Future Considerations

Author

Egger M, Bellmann R, Krause R, Boyer J, Jakšić D, and Hoenigl M

Subjects
invasive fungal infections, aspergillosis, mucormycosis, salvage therapy, Infectious and parasitic diseases, RC109-216
Abstract

Matthias Egger,1,2 Romuald Bellmann,3 Robert Krause,1,2 Johannes Boyer,1 Daniela Jakšić,4 Martin Hoenigl1,2,5,6 1Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Graz, Austria; 2Biotechmed-Graz, Graz, Austria; 3Clinical Pharmacokinetics Unit, Division of Intensive Care and Emergency Medicine, Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria; 4Department of Microbiology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; 5Clinical and Translational Fungal-Working Group, University of California San Diego, San Diego, CA, USA; 6Translational Medical Mycology Research Unit, ECMM Excellence Center for Medical Mycology, Medical University of Graz, Graz, AustriaCorrespondence: Martin Hoenigl, Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz, 8036, Austria, Tel +43 31638531425, Email hoeniglmartin@gmail.comAbstract: Invasive mold diseases are devastating systemic infections which demand meticulous care in selection, dosing, and therapy monitoring of antifungal drugs. Various circumstances regarding PK/PD properties of the applied drug, resistance/tolerance of the causative pathogen or host intolerability can lead to failure of the initial antifungal therapy. This necessitates treatment adaption in the sense of switching antifungal drug class or potentially adding another drug for a combination therapy approach. In the current state of drastically limited options of antifungal drug classes adaption of therapy remains challenging. Current guidelines provide restricted recommendations only and emphasize individual approaches. However, novel antifungals, incorporating innovative mechanisms of action, show promising results in late stage clinical development. These will expand options for salvage therapy in the future potentially as monotherapy or in combination with conventional or other novel antifungals. We outline current recommendations for salvage therapy including PK/PD considerations as well as elucidate possible future treatment options for invasive aspergillosis and mucormycosis.Keywords: invasive fungal infections, aspergillosis, mucormycosis, salvage therapy

Published
2023

6. Testing Critical Slowing Down as a Bifurcation Indicator in a Low-dissipation Dynamical System

Author

Marconi, M., Metayer, C., Acquaviva, A., Boyer, J. M., Gomel, A., Quiniou, T., Masoller, C., Giudici, M., and Tredicce, J. R.

Subjects
Nonlinear Sciences - Pattern Formation and Solitons, Nonlinear Sciences - Chaotic Dynamics
Abstract

We study a two-dimensional low-dissipation dynamical system with a control parameter that is swept linearly in time across a transcritical bifurcation. We investigate the relaxation time of a perturbation applied to a variable of the system and we show that critical slowing down may occur at a parameter value well above the bifurcation point. We test experimentally the occurrence of critical slowing down by applying a perturbation to the accessible control parameter and we find that this perturbation leaves the system behavior unaltered, thus providing no useful information on the occurrence of critical slowing down. The theoretical analysis reveals the reasons why these tests fail in predicting an incoming bifurcation.

Published
2020
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20. Spiritual and Religious Resources in African American Women

Author

Cheadle, Alyssa CD, Dunkel Schetter, Christine, Gaines Lanzi, Robin, Reed Vance, Maxine, Sahadeo, Latoya S, Shalowitz, Madeleine U, Vance, M, Minkovitz, CS, O’Campo, P, Schafer, P, Sankofa, N, Walton, K, Wagenaar, K, Shalowitz, M, Adam, E, Duncan, G, Schoua-Glusberg, A, McKinney, C, McDade, T, Simon, C, Clark-Kauffman, E, Jones, L, Hobel, C, Schetter, C Dunkel, Lu, MC, Chung, B, Jones, F, Serafin, D, Young, D, Evans, S, Ruffin, J, Woolard, R, Thorp, J, DeClerque, J, Dolbier, C, Lorenz, C, Sahadeo, LS, Salisbury, K, Patchen, L, Ramey, SL, Lanzi, RG, Klerman, LV, Miodovnik, M, Ramey, CT, Randolph, L, Timraz, N, German, R, Chinchilli, VM, Belue, R, Faulkner, G Brown, Hillemeier, M, Paul, I, Shaffer, ML, Snyder, G, Lehman, E, Stetter, C, Schmidt, J, Cerullo, K, Whisler, S, Fisher, J, Boyer, J, Payton, M, Evans, VJ, Raju, TNK, Weglicki, L, Spittel, M, Willinger, M, Bryan, Y, Phillippe, M, and Fuentes-Afflick, E

Subjects
Psychology, Clinical and Health Psychology, Social and Personality Psychology, Applied and Developmental Psychology, Depression, Behavioral and Social Science, Basic Behavioral and Social Science, Clinical Research, Pediatric, Mental Health, Reproductive health and childbirth, Good Health and Well Being, Community and Child Health Network, Applied and developmental psychology, Clinical and health psychology, Social and personality psychology
Abstract

Many women experience depressive symptoms after birth, and rates among African Americans are as high as 40 percent. Spirituality and religiosity are valued in African American communities, but their relevance to new mothers has not been empirically tested. We examined effects of religiosity and spirituality on trajectories of depressive symptoms during the year following childbirth. Data were collected by the Eunice Kennedy Shriver NICHD Community and Child Health Network (CCHN) focused on maternal-child health disparities. The sample consisted of 702 low SES African American predominantly Christian women. Participants were interviewed in their homes throughout the year following a birth. Spirituality and religiosity each independently predicted changes in depressive symptoms with low levels predicting increases over time. Effects of religiosity were mediated by a woman's spirituality. Religiosity and spirituality functioned as significant, interrelated protective factors in this study which provides novel insight about lower income African American women following birth.

Published
2015

23. Search for Correlations between HiRes Stereo Events and Active Galactic Nuclei

Author

Abbasi, R. U., Abu-Zayyad, T., Allen, M., Amman, J. F., Archbold, G., Belov, K., Belz, J. W., BenZvi, S. Y., Bergman, D. R., Blake, S. A., Boyer, J. H., Brusova, O. A., Burt, G. W., Cannon, C., Cao, Z., Deng, W., Fedorova, Y., Findlay, J., Finley, C. B., Gray, R. C., Hanlon, W. F., Hoffman, C. M., Holzscheiter, M. H., Hughes, G., Huntemeyer, P., Ivanov, D., Jones, B. F, Jui, C. C. H., Kim, K., Kirn, M. A., Knapp, B. C., Loh, E. C., Maestas, M. M., Manago, N., Mannel, E. J., Marek, L. J., Martens, K., Matthews, J. N., Moore, S. A., O'Neill, A., Painter, C. A., Perera, L., Reil, K., Riehle, R., Roberts, M. D., Sasaki, D. Rodriguez N., Schnetzer, S. R., Scott, L. M., Seman, M., Sinnis, G., Smith, J. D., Snow, R., Sokolsky, P., Song, C., Springer, R. W., Stokes, B. T., Stratton, S. R., Thomas, J. R., Thomas, S. B., Thomson, G. B., Tupa, D., Wiencke, L. R., Zech, A., and Zhang, X.

Subjects
Astrophysics
Abstract

We have searched for correlations between the pointing directions of ultrahigh energy cosmic rays observed by the High Resolution Fly's Eye experiment and Active Galactic Nuclei (AGN) visible from its northern hemisphere location. No correlations, other than random correlations, have been found. We report our results using search parameters prescribed by the Pierre Auger collaboration. Using these parameters, the Auger collaboration concludes that a positive correlation exists for sources visible to their southern hemisphere location. We also describe results using two methods for determining the chance probability of correlations: one in which a hypothesis is formed from scanning one half of the data and tested on the second half, and another which involves a scan over the entire data set. The most significant correlation found occurred with a chance probability of 24%., Comment: 13 pages, 1 table, 5 figures

Published
2008
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24. An upper limit on the electron-neutrino flux from the HiRes detector

Author

Abbasi, R. U., Abu-Zayyad, T., Allen, M., Amann, J. F., Archbold, G., Belov, K., Belz, J. W., Zvi, S. Y. Ben, Bergman, D. R., Biesiadecka, A., Blake, S. A., Boyer, J. H., Brusova, O. A., Burt, G. W., Cannon, C., Cao, Z., Deng, W., Fedorova, Y., Findlay, J., Finley, C. B., Gray, R. C., Hanlon, W. F., Hoffman, C. M., Holzscheiter, M. H., Hughes, G., Huentemeyer, P., Ivanov, D., Jones, B. F, Jui, C. C. H., Kim, K., Kirn, M. A., Knapp, B. C., Loh, E. C., Maestas, M. M., Manago, N., Mannel, E. J., Marek, L. J., Martens, K., Matthews, J. A. J., Matthews, J. N., Moore, S. A., O'Neill, A., Painter, C. A., Perera, L., Reil, K., Riehle, R., Roberts, M. D., Rodriguez, D., Sasaki, M., Schnetzer, S. R., Scott, L. M., Seman, M., Sinnis, G., Smith, J. D., Snow, R., Sokolsky, P., Song, C., Springer, R. W., Stokes, B. T., Stratton, S. R., Thomas, J. R., Thomas, S. B., Thomson, G. B., Tupa, D., Wiencke, L. R., Zech, A., and Zhang, X.

Subjects
Astrophysics
Abstract

Air-fluorescence detectors such as the High Resolution Fly's Eye (HiRes) detector are very sensitive to upward-going, Earth-skimming ultrahigh energy electron-neutrino-induced showers. This is due to the relatively large interaction cross sections of these high-energy neutrinos and to the Landau-Pomeranchuk-Migdal (LPM) effect. The LPM effect causes a significant decrease in the cross sections for bremsstrahlung and pair production, allowing charged-current electron-neutrino-induced showers occurring deep in the Earth's crust to be detectable as they exit the Earth into the atmosphere. A search for upward-going neutrino-induced showers in the HiRes-II monocular dataset has yielded a null result. From an LPM calculation of the energy spectrum of charged particles as a function of primary energy and depth for electron-induced showers in rock, we calculate the shape of the resulting profile of these showers in air. We describe a full detector Monte Carlo simulation to determine the detector response to upward-going electron-neutrino-induced cascades and present an upper limit on the flux of electron-neutrinos., Comment: 13 pages, 3 figures. submitted to Astrophysical Journal

Published
2008
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26. Measurement of the Cosmic Ray Energy Spectrum and Composition from 10^{17} to 10^{18.3} eV Using a Hybrid Fluorescence Technique

Author

Abu-Zayyad, T., Belov, K., Bird, D. J., Boyer, J., Cao, Z., Catanese, M., Chen, G. F., Clay, R. W., Covault, C. E., Dai, H. Y., Dawson, B. R., Elbert, J. W., Fick, B. E., Fortson, L. F., Fowler, J. W., Gibbs, K. G., Glasmacher, M. A. K., Green, K. D., Ho, Y., Huang, A., Jui, C. C., Kidd, M. J., Kieda, D. B., Knapp, B. C., Ko, S., Larsen, C. G., Lee, W., Loh, E. C., Mannel, E. J., Matthews, J., Matthews, J. N., Newport, B. J., Nitz, D. F., Ong, R. A., Simpson, K. M., Smith, J. D., Sinclair, D., Sokolsky, P., Sommers, P., Song, C., Tang, J. K. K., Thomas, S. B., van der Velde, J., Wiencke, L. R., Wilkinson, C. R., Yoshida, S., and Zhang, X. Z.

Subjects
Astrophysics
Abstract

We study the spectrum and average mass composition of cosmic rays with primary energies between 10^{17} eV and 10^{18} eV using a hybrid detector consisting of the High Resolution Fly's Eye (HiRes) prototype and the MIA muon array. Measurements have been made of the change in the depth of shower maximum as a function of energy. A complete Monte Carlo simulation of the detector response and comparisons with shower simulations leads to the conclusion that the cosmic ray intensity is changing f rom a heavier to a lighter composition in this energy range. The spectrum is consistent with earlier Fly's Eye measurements and supports the previously found steepening near 4 \times 10^{17} eV ., Comment: 39 pages, 15 figures, in revtex4 epsf style, submited to APJ

Published
2000
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27. A Multi-Component Measurement of the Cosmic Ray Composition Between 10^{17} eV and 10^{18} eV

Author

Abu-Zayyad, T., Belov, K., Bird, D. J., Boyer, J., Cao, Z., Catanese, M., Chen, G. F., Clay, R. W., Covault, C. E., Cronin, J. W., Dai, H. Y., Dawson, B. R., Elbert, J. W., Fick, B. E., Fortson, L. F., Fowler, J. W., Gibbs, K. G., Glasmacher, M. A. K., Green, K. D., Ho, Y., Huang, A., Jui, C. C., Kidd, M. J., Kieda, D. B., Knapp, B. C., Ko, S., Larsen, C. G., Lee, W., Loh, E. C., Mannel, E. J., Matthews, J., Matthews, J. N., Newport, B. J., Nitz, D. F., Ong, R. A., Simpson, K. M., Smith, J. D., Sinclair, D., Sokolsky, P., Sommers, P., Song, C., Tang, J. K. K., Thomas, S. B., van der Velde, J. C., Wiencke, L. R., Wilkinson, C. R., Yoshida, S., and Zhang, X. Z.

Subjects
Astrophysics
Abstract

The average mass composition of cosmic rays with primary energies between $10^{17}$eV and $10^{18}$eV has been studied using a hybrid detector consisting of the High Resolution Fly's Eye (HiRes) prototype and the MIA muon array. Measurements have been made of the change in the depth of shower maximum, $X_{max}$, and in the change in the muon density at a fixed core location, $\rho_\mu(600m)$, as a function of energy. The composition has also been evaluated in terms of the combination of $X_{max}$ and $\rho_\mu(600m)$. The results show that the composition is changing from a heavy to lighter mix as the energy increases., Comment: 14 pages including 3 figures in revtex epsf style, submited to PRL

Published
1999
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43. Inclusive charged hadron and K0 production in two-photon interactions

Author

Cords, D, Boyer, J, Butler, F, Gidal, G, Abrams, GS, Amidei, D, Baden, AR, Barklow, T, Boyarski, AM, Burchat, PR, Burke, DL, Dorfan, JM, Feldman, GJ, Gladney, L, Gold, MS, Goldhaber, G, Haggerty, J, Hanson, G, Hayes, K, Herrup, D, Hollebeek, RJ, Innes, WR, Jaros, JA, Juricic, I, Kadyk, JA, Karlen, D, Lankford, AJ, Larsen, RR, LeClaire, BW, Levi, ME, Lockyer, NS, Lüth, V, Nelson, ME, Ong, RA, Perl, ML, Riles, K, Rowson, PC, Schaad, T, Schellman, H, Schmidke, WB, Trilling, GH, Wood, DR, and Yelton, JM

Subjects
Nuclear & Particles Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Astronomical and Space Sciences, Mathematical Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

The inclusive transverse momentum distributions of charged hadrons and K0's produced in tagged photon-photon collisions, are measured and compared to model calculations up to a pT of 5 GeV/c. The relative abundance of K0's favor the inclusion of charm. © 1993.

Published
1993

44. Inclusive Charged Hadron and K{sup 0} Production in Two-Photon Interactions

Author

Cords, D., Boyer, J., Butler, F., Gidal, G., Abrams, G.S., Amidei, D., Baden, A.R., Barklow, T., Boyarski, A.M., Burchat, P.R., Burke, D.L., Dorfan, J.M., Feldman, G.J., Gladney, L., Gold, M.S., Goldhaber, G., Haggerty, J., Hanson, G., Hayes, K., Herrup, D., Hollebeek, R.J., Innes, W.R., Jaros, J.A., Juricic, I., Kadyk, J.A., Karlen, D., Lankford, A.J., Larsen, R.R., LeClaire, B.W., Levi, M.E., Lockyer, N.S., Luth, V., Nelson, M.E., Ong, R.A., Perl, M.L., Riles, K., Rowson, P.C., Schaad, T., Schellman, H., Scmidke, W.B., Trilling, G.H., Wood, D.R., and Yelton, J.M.

Published
1992

45. Search for the production of the final states τ+τ-e+e-, τ+τ-μ+μ-, and τ+τ-π+π- in e+e- collisions at √s =29 GeV

Author

Barklow, T, Innes, WR, Petradza, M, Snyder, A, Stoker, DP, Wagner, SR, Abrams, GS, Amidei, D, Baden, AR, Boyarski, AM, Boyer, J, Burchat, PR, Burke, DL, Butler, F, Dorfan, JM, Feldman, GJ, Gidal, G, Gladney, L, Gold, MS, Goldhaber, G, Golding, LJ, Haggerty, J, Hanson, G, Hayes, K, Herrup, D, Hollebeek, RJ, Jaros, JA, Juricic, I, Kadyk, JA, Karlen, D, Lankford, AJ, Larsen, RR, LeClaire, BW, Levi, ME, Lockyer, NS, Lüth, V, Nelson, ME, Ong, RA, Perl, ML, Richter, B, Riles, K, Rowson, PC, Schaad, T, Schellman, H, Schmidke, WB, Sheldon, PD, Trilling, GH, Wood, DR, and Yelton, JM

Subjects
Mathematical Sciences, Physical Sciences, Engineering, General Physics
Abstract

We have searched for the reaction e+e-, where f is either an electron, muon, or charged pion, at s =29 GeV using the Mark II detector at the SLAC PEP storage ring. One candidate event is found while 2.3 events are expected from known processes. We would expect to see 11 events if the cross section for e+e- at s=29 GeV were enhanced by the factor of 4.7 which the ALEPH Collaboration reports for s=91 GeV. We also look for e+e- and e+e-, and for e+e-, using a similar analysis procedure, and see the number of events predicted by the standard model. © 1992 The American Physical Society.

Published
1992

46. Search for the production of the final states tau + tau -e+e-, tau + tau - micro+ micro-, and tau + tau - pi + pi - in e+e- collisions at sqrt s =29 GeV.

Author

Barklow, T, Innes, WR, Petradza, M, Snyder, A, Stoker, DP, Wagner, SR, Abrams, GS, Amidei, D, Baden, AR, Boyarski, AM, Boyer, J, Burchat, PR, Burke, DL, Butler, F, Dorfan, JM, Feldman, GJ, Gidal, G, Gladney, L, Gold, MS, Goldhaber, G, Golding, LJ, Haggerty, J, Hanson, G, Hayes, K, Herrup, D, Hollebeek, RJ, Jaros, JA, Juricic, I, Kadyk, JA, Karlen, D, Lankford, AJ, Larsen, RR, LeClaire, BW, Levi, ME, Lockyer, NS, Lüth, V, Nelson, ME, Ong, RA, Perl, ML, Richter, B, Riles, K, Rowson, PC, Schaad, T, Schellman, H, Schmidke, WB, Sheldon, PD, Trilling, GH, Wood, DR, and Yelton, JM

Subjects
General Physics, Physical Sciences, Mathematical Sciences, Engineering
Abstract

We have searched for the reaction e+e-, where f is either an electron, muon, or charged pion, at s =29 GeV using the Mark II detector at the SLAC PEP storage ring. One candidate event is found while 2.3 events are expected from known processes. We would expect to see 11 events if the cross section for e+e- at s=29 GeV were enhanced by the factor of 4.7 which the ALEPH Collaboration reports for s=91 GeV. We also look for e+e- and e+e-, and for e+e-, using a similar analysis procedure, and see the number of events predicted by the standard model. © 1992 The American Physical Society.

Published
1992

48. Search for elastic nondiagonal lepton-pair production in e+e- annihilation at √s =29 GeV

Author

Gomez-Cadenas, JJ, Heusch, CA, Abrams, G, Adolphsen, CE, Akerlof, C, Alexander, JP, Alvarez, M, Amidei, D, Baden, AR, Ballam, J, Barish, BC, Barklow, T, Barnett, BA, Bartelt, J, Blockus, D, Bonvicini, G, Boyarski, A, Boyer, J, Brabson, B, Breakstone, A, Brom, JM, Bulos, F, Burchat, PR, Burke, DL, Butler, F, Calvino, F, Cence, RJ, Chapman, J, Cords, D, Coupal, DP, DeStaebler, HC, Dorfan, DE, Dorfan, JM, Drell, PS, Feldman, GJ, Fernandez, E, Field, RC, Ford, WT, Fordham, C, Frey, R, Fujino, D, Gan, KK, Gidal, G, Gladney, L, Glanzman, T, Gold, MS, Goldhaber, G, Golding, L, Green, A, Grosse-Wiesmann, P, Haggerty, J, Hanson, G, Harr, R, Harris, FA, Hawkes, CM, Hayes, K, Herrup, D, Himel, T, Hoenk, M, Hollebeek, RJ, Hutchinson, D, Hylen, J, Innes, WR, Jaffre, M, Jaros, JA, Juricic, I, Kadyk, JA, Karlen, D, Kent, J, Klein, SR, Koide, A, Koska, W, Kozanecki, W, Lankford, AJ, Larsen, RR, LeClaire, BW, Levi, ME, Li, Z, Litke, AM, Lockyer, NS, Lüth, V, Matteuzzi, C, Matthews, JAJ, Meyer, DI, Milliken, BD, Moffeit, KC, Müller, L, Nash, J, Nelson, ME, Nitz, D, Ogren, H, Ong, RA, O’Shaughnessy, KF, Parker, SI, Peck, C, Petersen, A, Petradza, M, Porter, FC, Rankin, P, and Richter, B

Subjects
Mathematical Sciences, Physical Sciences, Engineering, General Physics
Abstract

We have searched for the annihilation of e+e- into the exclusive channels e and at s =29 GeV, using 226 and 133 pb-1, respectively, of data taken with the Mark II detector at the SLAC storage ring PEP. The resulting candidate sample is compatible with the expected background from pair production. Our analysis yields 95%-C.L. cross-section limits of e/

Published
1991

49. Search for elastic nondiagonal lepton-pair production in e+e- annihilation at sqrt s =29 GeV.

Author

Gomez-Cadenas, JJ, Heusch, CA, Abrams, G, Adolphsen, CE, Akerlof, C, Alexander, JP, Alvarez, M, Amidei, D, Baden, AR, Ballam, J, Barish, BC, Barklow, T, Barnett, BA, Bartelt, J, Blockus, D, Bonvicini, G, Boyarski, A, Boyer, J, Brabson, B, Breakstone, A, Brom, JM, Bulos, F, Burchat, PR, Burke, DL, Butler, F, Calvino, F, Cence, RJ, Chapman, J, Cords, D, Coupal, DP, DeStaebler, HC, Dorfan, DE, Dorfan, JM, Drell, PS, Feldman, GJ, Fernandez, E, Field, RC, Ford, WT, Fordham, C, Frey, R, Fujino, D, Gan, KK, Gidal, G, Gladney, L, Glanzman, T, Gold, MS, Goldhaber, G, Golding, L, Green, A, Grosse-Wiesmann, P, Haggerty, J, Hanson, G, Harr, R, Harris, FA, Hawkes, CM, Hayes, K, Herrup, D, Himel, T, Hoenk, M, Hollebeek, RJ, Hutchinson, D, Hylen, J, Innes, WR, and Jaffre, M

Subjects
General Physics, Physical Sciences
Abstract

We have searched for the annihilation of e+e- into the exclusive channels e and at s =29 GeV, using 226 and 133 pb-1, respectively, of data taken with the Mark II detector at the SLAC storage ring PEP. The resulting candidate sample is compatible with the expected background from pair production. Our analysis yields 95%-C.L. cross-section limits of e/

Published
1991

50. Measurement of the total hadronic cross section in e+e- annihilation at sqrt s =29 GeV.

Author

von Zanthier C, de Boer W, Grindhammer, G, Hylen, J, Harral, B, Hearty, C, Labarga, L, Matthews, J, Schaad, M, Abrams, G, Adolphsen, CE, Akerlof, C, Alexander, JP, Alvarez, M, Baden, AR, Ballam, J, Barish, BC, Barklow, T, Barnett, BA, Bartelt, J, Blockus, D, Bonvicini, G, Boyarski, A, Boyer, J, Brabson, B, Breakstone, A, Brom, JM, Bulos, F, Burchat, PR, Burke, DL, Butler, F, Calvino, F, Cence, RJ, Chapman, J, Cords, D, Coupal, DP, DeStaebler, HC, Dorfan, DE, Dorfan, JM, Drell, PS, Feldman, GJ, Fernandez, E, Field, RC, Ford, WT, Fordham, C, Frey, R, Fujino, D, Gan, KK, Gidal, G, Glanzman, T, Goldhaber, G, Green, A, Grosse-Wiesmann, P, Haggerty, J, Hanson, G, Harr, R, Harris, FA, Hawkes, CM, Hayes, K, Herrup, D, Heusch, CA, Himel, T, Hoenk, M, and Hutchinson, D

Subjects
Nuclear & Particles Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

A precise measurement of the ratio R of the total cross section e+e-hadrons to the pointlike cross section e+e-+- at a center-of-mass energy of 29.0 GeV is presented. The data were taken with the upgraded Mark II detector at the SLAC storage ring PEP. The result is R=3.920.050.09. The luminosity has been determined with three independent luminosity monitors measuring Bhabha scattering at different angular intervals. Recent calculations of higher-order QED radiative corrections are used to estimate the systematic error due to missing higher-order radiative corrections in the Monte Carlo event generators. © 1991 The American Physical Society.

Published
1991

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