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2. Improving Student Performance through the Use of Active Learning Strategies.

Author

Blakey, David, Larvenz, Kenneth, McKee, Michele, and Thomas, Regina

Abstract

This report addresses the problem of apathy and the unwillingness of middle level students to meet basic standards, evidenced by a lack of student performance and participation and by an attitude of indifference. The targeted population for this study consisted of seventh and eighth grade general music students in an economically and culturally diverse urban community in western Illinois. An emphasis was placed on incorporating active learning strategies in order to improve student interest and participation. The report includes an analysis of probable causes of student disengagement; a plan of intervention based on increasing on-task behavior, increasing personal insight and appreciation, and increasing student recall, comprehension, and transfer of course content; a discussion of the results; and recommendations. Contains 34 references. (BT)

Published
2000

3. Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM-ICCVAM/NICEATM Considerations for Regulatory Use

Author

Corvi, Raffaella, Ahr, Hans-Jürgen, Albertini, Silvio, Blakey, David H., Clerici, Libero, Coecke, Sandra, Douglas, George R., Gribaldo, Laura, Groten, John P., Haase, Bernd, Hamernik, Karen, Hartung, Thomas, Inoue, Tohru, Indans, Ian, Maurici, Daniela, Orphanides, George, Rembges, Diana, Sansone, Susanna-Assunta, Snape, Jason R., Toda, Eisaku, Tong, Weida, van Delft, Joost H., Weis, Brenda, and Schechtman, Leonard M.

Published
2006

5. Supplementary Methods, Figure Legend from MEDI0639: A Novel Therapeutic Antibody Targeting Dll4 Modulates Endothelial Cell Function and Angiogenesis In Vivo

Author

Jenkins, David W., primary, Ross, Sarah, primary, Veldman-Jones, Margaret, primary, Foltz, Ian N., primary, Clavette, Brandon C., primary, Manchulenko, Kathy, primary, Eberlein, Cath, primary, Kendrew, Jane, primary, Petteruti, Philip, primary, Cho, Song, primary, Damschroder, Melissa, primary, Peng, Li, primary, Baker, Dawn, primary, Smith, Neil R., primary, Weir, Hazel M., primary, Blakey, David C., primary, Bedian, Vahe, primary, and Barry, Simon T., primary

Published
2023
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6. Data from Novel Neutralizing Hedgehog Antibody MEDI-5304 Exhibits Antitumor Activity by Inhibiting Paracrine Hedgehog Signaling

Author

Michaud, Neil R., primary, Wang, Youzhen, primary, McEachern, Kristen A., primary, Jordan, Jerold J., primary, Mazzola, Anne Marie, primary, Hernandez, Axel, primary, Jalla, Sanjoo, primary, Chesebrough, Jon W., primary, Hynes, Mark J., primary, Belmonte, Matthew A., primary, Wang, Lidong, primary, Kang, Jaspal S., primary, Jovanović, Jelena, primary, Laing, Naomi, primary, Jenkins, David W., primary, Hurt, Elaine, primary, Liang, Meina, primary, Frantz, Christopher, primary, Hollingsworth, Robert E., primary, Simeone, Diane M., primary, Blakey, David C., primary, and Bedian, Vahe, primary

Published
2023
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7. Supplementary Materials and Methods and Supplementary Figures 1 through 9 from Novel Neutralizing Hedgehog Antibody MEDI-5304 Exhibits Antitumor Activity by Inhibiting Paracrine Hedgehog Signaling

Author

Michaud, Neil R., primary, Wang, Youzhen, primary, McEachern, Kristen A., primary, Jordan, Jerold J., primary, Mazzola, Anne Marie, primary, Hernandez, Axel, primary, Jalla, Sanjoo, primary, Chesebrough, Jon W., primary, Hynes, Mark J., primary, Belmonte, Matthew A., primary, Wang, Lidong, primary, Kang, Jaspal S., primary, Jovanović, Jelena, primary, Laing, Naomi, primary, Jenkins, David W., primary, Hurt, Elaine, primary, Liang, Meina, primary, Frantz, Christopher, primary, Hollingsworth, Robert E., primary, Simeone, Diane M., primary, Blakey, David C., primary, and Bedian, Vahe, primary

Published
2023
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8. Supplementary Legends from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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9. Supplementary Figure 4 from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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10. Supplementary Table 1, Figure Legends 1-6 from A Human Monoclonal Anti-ANG2 Antibody Leads to Broad Antitumor Activity in Combination with VEGF Inhibitors and Chemotherapy Agents in Preclinical Models

Author

Brown, Jeffrey L., primary, Cao, Z. Alexander, primary, Pinzon-Ortiz, Maria, primary, Kendrew, Jane, primary, Reimer, Corinne, primary, Wen, Shenghua, primary, Zhou, Joe Q., primary, Tabrizi, Mohammad, primary, Emery, Steve, primary, McDermott, Brenda, primary, Pablo, Lourdes, primary, McCoon, Patricia, primary, Bedian, Vahe, primary, and Blakey, David C., primary

Published
2023
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11. Supplementary Figure 3 from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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12. Supplementary Figure 5 from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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13. Appendix A from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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14. Supplementary Figures 1-6 from A Human Monoclonal Anti-ANG2 Antibody Leads to Broad Antitumor Activity in Combination with VEGF Inhibitors and Chemotherapy Agents in Preclinical Models

Author

Brown, Jeffrey L., primary, Cao, Z. Alexander, primary, Pinzon-Ortiz, Maria, primary, Kendrew, Jane, primary, Reimer, Corinne, primary, Wen, Shenghua, primary, Zhou, Joe Q., primary, Tabrizi, Mohammad, primary, Emery, Steve, primary, McDermott, Brenda, primary, Pablo, Lourdes, primary, McCoon, Patricia, primary, Bedian, Vahe, primary, and Blakey, David C., primary

Published
2023
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15. Supplementary Figure 1 from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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16. Supplementary Tables from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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17. Supplementary Figure 2 from MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, primary, Meyer, Tim, primary, Sodergren, Mikael H., primary, Basu, Bristi, primary, Chee, Cheng Ean, primary, Huang, Kai-Wen, primary, Palmer, Daniel H., primary, Ma, Yuk Ting, primary, Evans, T.R. Jeff, primary, Spalding, Duncan R.C., primary, Pai, Madhava, primary, Sharma, Rohini, primary, Pinato, David J., primary, Spicer, James, primary, Hunter, Sarah, primary, Kwatra, Vineet, primary, Nicholls, Joanna P., primary, Collin, David, primary, Nutbrown, Robert, primary, Glenny, Helen, primary, Fairbairn, Sonia, primary, Reebye, Vikash, primary, Voutila, Jon, primary, Dorman, Stephanie, primary, Andrikakou, Pinelopi, primary, Lloyd, Peter, primary, Felstead, Steve, primary, Vasara, Jenni, primary, Habib, Robert, primary, Wood, Chris, primary, Saetrom, Pal, primary, Huber, Hans E., primary, Blakey, David C., primary, Rossi, John J., primary, and Habib, Nagy, primary

Published
2023
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18. Data from Dual IGF-I/II–Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Author

Gao, Jin, primary, Chesebrough, Jon W., primary, Cartlidge, Susan A., primary, Ricketts, Sally-Ann, primary, Incognito, Leonard, primary, Veldman-Jones, Margaret, primary, Blakey, David C., primary, Tabrizi, Mohammad, primary, Jallal, Bahija, primary, Trail, Pamela A., primary, Coats, Steven, primary, Bosslet, Klaus, primary, and Chang, Yong S., primary

Published
2023
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19. Supplementary Figures 1-4, Tables 1-2 from Dual IGF-I/II–Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Author

Gao, Jin, primary, Chesebrough, Jon W., primary, Cartlidge, Susan A., primary, Ricketts, Sally-Ann, primary, Incognito, Leonard, primary, Veldman-Jones, Margaret, primary, Blakey, David C., primary, Tabrizi, Mohammad, primary, Jallal, Bahija, primary, Trail, Pamela A., primary, Coats, Steven, primary, Bosslet, Klaus, primary, and Chang, Yong S., primary

Published
2023
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23. Enhancing SIRT1 Gene Expression Using Small Activating RNAs: A Novel Approach for Reversing Metabolic Syndrome

Author

Andrikakou, Pinelopi, primary, Reebye, Vikash, additional, Vasconcelos, Daniel, additional, Yoon, Sorah, additional, Voutila, Jon, additional, George, Andrew J.T., additional, Swiderski, Piotr, additional, Habib, Robert, additional, Catley, Matthew, additional, Blakey, David, additional, Habib, Nagy A., additional, Rossi, John J., additional, and Huang, Kai-Wen, additional

Published
2022
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26. Immunotoxins

Author

Blakey, David C., Rugstad, Hans Erik, editor, Endresen, Liv, editor, and Førre, Øystein, editor

Published
1992
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29. International study of factors affecting human chromosome translocations

Author

Sigurdson, Alice J., Ha, Mina, Hauptmann, Michael, Bhatti, Parveen, Sram, Radim J., Beskid, Olena, Tawn, E. Janet, Whitehouse, Caroline A., Lindholm, Carita, Nakano, Mimako, Kodama, Yoshiaki, Nakamura, Nori, Vorobtsova, Irena, Oestreicher, Ursula, Stephan, Günther, Yong, Lee C., Bauchinger, Manfred, Schmid, Ernst, Chung, Hai Won, Darroudi, Firouz, Roy, Laurence, Voisin, Phillipe, Barquinero, Joan F., Livingston, Gordon, Blakey, David, Hayata, Isamu, Zhang, Wei, Wang, Chunyan, Bennett, L. Michelle, Littlefield, L. Gayle, Edwards, Alan A., Kleinerman, Ruth A., and Tucker, James D.

Published
2008
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31. In vivo erythrocyte micronucleus assay : III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test

Author

Hayashi, Makoto, MacGregor, James T., Gatehouse, David G., Blakey, David H., Dertinger, Stephen D., Abramsson-Zetterberg, Lilianne, Krishna, Gopala, Morita, Takeshi, Russo, Antonella, Asano, Norihide, Suzuki, Hiroshi, Ohyama, Wakako, and Gibson, Dave

Published
2007
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34. MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Author

Sarker, Debashis, primary, Plummer, Ruth, additional, Meyer, Tim, additional, Sodergren, Mikael H., additional, Basu, Bristi, additional, Chee, Cheng Ean, additional, Huang, Kai-Wen, additional, Palmer, Daniel H., additional, Ma, Yuk Ting, additional, Evans, T.R. Jeff, additional, Spalding, Duncan R.C., additional, Pai, Madhava, additional, Sharma, Rohini, additional, Pinato, David J., additional, Spicer, James, additional, Hunter, Sarah, additional, Kwatra, Vineet, additional, Nicholls, Joanna P., additional, Collin, David, additional, Nutbrown, Robert, additional, Glenny, Helen, additional, Fairbairn, Sonia, additional, Reebye, Vikash, additional, Voutila, Jon, additional, Dorman, Stephanie, additional, Andrikakou, Pinelopi, additional, Lloyd, Peter, additional, Felstead, Steve, additional, Vasara, Jenni, additional, Habib, Robert, additional, Wood, Chris, additional, Saetrom, Pal, additional, Huber, Hans E., additional, Blakey, David C., additional, Rossi, John J., additional, and Habib, Nagy, additional

Published
2020
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36. Phase Ib dose escalation and cohort expansion study of the novel myeloid differentiating agent MTL-CEBPA in combination with sorafenib in patients with advanced hepatocellular carcinoma (HCC).

Author

Sarker, Debashis, primary, Sodergren, Mikael, additional, Plummer, Elizabeth Ruth, additional, Basu, Bristi, additional, Meyer, Tim, additional, Huang, Kai-Wen, additional, Evans, T.R. Jeffry, additional, Spalding, Duncan, additional, Ma, Yuk Ting, additional, Palmer, Daniel H., additional, Chee, Cheng Ean, additional, Pinato, David James, additional, Reebye, Vikash, additional, McVeigh, Daniel, additional, Raulf, Nina, additional, Vasara, Jenni, additional, Andrikakou, Pinelopi, additional, Habib, Robert, additional, Blakey, David, additional, and Habib, Nagy A., additional

Published
2020
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38. First-in-human phase I trial of small activating RNA (saRNA) oligonucleotide MTL-CEBPA in combination with sorafenib in patients with advanced hepatocellular carcinoma (HCC).

Author

Sarker, Debashis, primary, Sodergren, Mikael, additional, Plummer, Elizabeth Ruth, additional, Basu, Bristi, additional, Meyer, Tim, additional, Huang, Kai-Wen, additional, Evans, T.R. Jeffry, additional, Spalding, Duncan, additional, Ma, Yuk Ting, additional, Palmer, Daniel H., additional, Chee, Cheng Ean, additional, Pinato, David James, additional, Reebye, Vikash, additional, McVeigh, Daniel, additional, Raulf, Nina, additional, Vasara, Jenni, additional, Andrikakou, Pinelopi, additional, Habib, Robert, additional, Blakey, David, additional, and Habib, Nagy A., additional

Published
2020
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39. Toward antibody-directed 'abzyme' prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing

Author

Wentworth, Paul, Datta, Anita, Blakey, David, Boyle, Tom, Partridge, Lynda J., and Blackburn, G. Michael

Subjects
Antineoplastic agents -- Research, Cancer, Science and technology
Abstract

The possible use of antibody-directed 'abzyme' prodrug therapy, a method which uses catalytic antibody rather than bacterial enzyme to improve on antibody-directed enzyme prodrug therapy for repeatable targeted cancer chemotherapy, is tested. A catalytic antibody that can hydrolyze the carbamate prodrug 1 to create the corresponding cytotoxic mustard, was developed. This abzyme, EA11-D7, and prodrug 1 were able to destroy cultured human colonic carcinoma.

Published
1996

45. Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice

Author

Zhou, Jiehua, primary, Li, Haitang, additional, Xia, Xin, additional, Herrera, Alberto, additional, Pollock, Nicolette, additional, Reebye, Vikash, additional, Sodergren, Mikael H., additional, Dorman, Stephanie, additional, Littman, Bruce H., additional, Doogan, Declan, additional, Huang, Kai-Wen, additional, Habib, Robert, additional, Blakey, David, additional, Habib, Nagy A., additional, and Rossi, John J., additional

Published
2019
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