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Within the scope of the Helmholtz Metadata Collaboration (HMC), the ADVANCE project – Advanced metadata standards for biodiversity survey and monitoring data: supporting of research and conservation – aimed at supporting rich metadata generation with interoperable metadata standards and semantic artefacts that facilitate data access, integration and reuse across terrestrial, freshwater and marine realms. HMC's mission is to facilitate the discovery, access, machine-readability, and reuse of research data across and beyond the Helmholtz Association.We revised, adapted and expanded existing metadata schemas, vocabularies and thesauri to build a FAIR metadata schema and a metadata entry form built on it for users to provide their metadata instances focused on biodiversity monitoring data. The schema is FAIR because it is both machine-interpretable and follows domain-relevant community standards. This report provides a general overview of the project results and instructions on how to access, re-use and complete the metadata form.

Today, human activities are the leading cause of severe environmental damages, especially regarding shortage and instability of natural resources. The sustainability concept was developed in response, to limit these risks and facilitate living conditions for future generations. Life and nature have historically been considered as inspiring in architecture among others, prompting an environmental-oriented sense of direction towards resolving present-day issues. Despite the proliferation of nature-inspired sciences, hardly any attention is paid to classifications and interconnections between these sciences regardless of benefits associated with such studies. However, the availability of such a classification and its use in present-day architecture can significantly contribute to the advancement of environmental sustainability.The current research has identified and presented a comprehensive framework of sciences inspired by life and nature (bio) and their relationship. The research method is qualitative-descriptive and focuses on articles containing the word ‘bio’, published in Springer publishers between 2020 and 2022. The review of the 1927 articles have led to a classification of biological studies into 11 groups (bionic, biomimetic, biomorphic, biofuel (biodiesel, bioalcohol, bioethanol, biohydrogen, and biogas), biomaterial, biohybrid, bioaerosol, biotechnology, bioalgorithm (biodesign intelligence and biomaterial intelligence), bioart (bio-inspired design and biodecoration), biophilia (biophilic design) and the relationship between them environmental sustainability. The outcome is a development of the theoretical knowledge about bio-inspired sciences and indicates that international bioscience studies mainly focus on biofuels and biotechnology, along the lines of reducing human activities’ impact on the environment, efficient use of natural resources, protect biodiversity, and a harmonious relationship between humans and the natural environment.

Today, human activities are the leading cause of severe environmental damages, especially regarding shortage and instability of natural resources. The sustainability concept was developed in response, to limit these risks and facilitate living conditions for future generations. Life and nature have historically been considered as inspiring in architecture among others, prompting an environmental-oriented sense of direction towards resolving present-day issues. Despite the proliferation of nature-inspired sciences, hardly any attention is paid to classifications and interconnections between these sciences regardless of benefits associated with such studies. However, the availability of such a classification and its use in present-day architecture can significantly contribute to the advancement of environmental sustainability. The current research has identified and presented a comprehensive framework of sciences inspired by life and nature (bio) and their relationship. The research method is qualitative-descriptive and focuses on articles containing the word ‘bio’, published in Springer publishers between 2020 and 2022. The review of the 1927 articles have led to a classification of biological studies into 11 groups (bionic, biomimetic, biomorphic, biofuel (biodiesel, bioalcohol, bioethanol, biohydrogen, and biogas), biomaterial, biohybrid, bioaerosol, biotechnology, bioalgorithm (biodesign intelligence and biomaterial intelligence), bioart (bio-inspired design and biodecoration), biophilia (biophilic design) and the relationship between them environmental sustainability. The outcome is a development of the theoretical knowledge about bio-inspired sciences and indicates that international bioscience studies mainly focus on biofuels and biotechnology, along the lines of reducing human activities’ impact on the environment, efficient use of natural resources, protect biodiversity, and a harmonious relationship between humans and the natural environment. [ABSTRACT FROM AUTHOR]

IntroductionIn this research, we introduce the NutriGreen dataset, which is a collection of images representing branded food products aimed for training segmentation models for detecting various labels on food packaging. Each image in the dataset comes with three distinct labels: one indicating its nutritional quality using the Nutri-Score, another denoting whether it is vegan or vegetarian origin with the V-label, and a third displaying the EU organic certification (BIO) logo.MethodsTo create the dataset, we have used semi-automatic annotation pipeline that combines domain expert annotation and automatic annotation using a deep learning model.ResultsThe dataset comprises a total of 10,472 images. Among these, the Nutri-Score label is distributed across five sub-labels: Nutri-Score grade A with 1,250 images, grade B with 1,107 images, grade C with 867 images, grade D with 1,001 images, and grade E with 967 images. Additionally, there are 870 images featuring the V-Label, 2,328 images showcasing the BIO label, and 3,201 images without before-mentioned labels. Furthermore, we have fine-tuned the YOLOv5 segmentation model to demonstrate the practicality of using these annotated datasets, achieving an impressive accuracy of 94.0%.DiscussionThese promising results indicate that this dataset has significant potential for training innovative systems capable of detecting food labels. Moreover, it can serve as a valuable benchmark dataset for emerging computer vision systems.

Copyright of Journal of Kirkuk University for Agricultural Sciences is the property of Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Most orthopteran insects are phytophagous and some are important pests in agriculture and forests. Many intestinal microflora of Orthoptera insects have been reported, primarily from Acridoidea and there have been few reports of other taxa. In this study, we collected 15 individuals representing five species (Ruspolia lineosa, Tetrix japonica, Erianthus versicolor, Gryllotalpa orientalis and Teleogryllus emma) belonging to five orthopteran superfamilies (Tettigonioidea, Tetrigoidea, Eumastacoidea, Gryllotalpoidea and Grylloidea) to characterise and compare the gut microbiota with greater taxonomic width by performing sequencing analysis of the 16S rRNA V4 region in gut material. A total of 606,053 high-quality sequences and 3,105 OTUs were acquired from 15 gut samples representing 24 phyla, 48 classes, 69 orders, 133 families and 219 genera. Firmicutes and bacteria were the most abundant phyla, followed by Bacteroidetes, Cyanobacteria, Actinobacteria and Acidobacteria. At the genus level, Serratia, Citrobacter, Wolbachia, Lactobacillus and Parabacteroides were the most predominant genera in R. lineosa, T. japonica, E. versicolor, G. orientalis and T. emma, respectively. Both Principal Coordinates Analysis (PCoA) and heatmap results revealed significant differences in bacterial community composition across species. Additionally, alpha diversity analysis indicated the bacterial richness was significantly different amongst the five species.

Bio Forming in Nature to Create Textile Printing Design for Hospitalization HouseResearch SummaryThe vast universe around us always pushes us to think, contemplate and learn. Nature is the basis on which all sciences and arts are based, and from this standpoint, the inspiration the structural and forming systems of all the vital forms of living creatures around us will enrich the field of textile printing design, especially if our destination is design for psychological support and resisting the repercussions of disease for the recovered and sick to improve their visual environment in the places of receiving treatment ( hospitalization) by applying the requirements of the healing environment and resisting disease through communicating with nature and its aesthetic values, which are derived and inspired by micro and ultrafine morphological details of cells of living organismswith interest in using color that has a positive impact on Human health to design psychologically which supports recoverees from illness . The design aims to meet all human requirements, which vary between functional and psychological requirements, and ignoring one of these requirements is a deficiency in the design process itself. The research problem is summarized in the use of the biological structure of living organisms to find innovative design solutions for textile printing fabrics for hospitalization rooms, which in turn contribute to Psychological support for recovered and sick people.The importance of the research is summarized in the development of a methodology to take advantage of the aesthetic values of biological forms under the microscope as one of the sources of creativity and psychological support for the recovered and sick people, inspiration for the biosynthesis of nature is an important moral message for the recovered and the sick. It is also an important trend for a textile printing designer, in-depth study enables us to understand the laws and relationships that are govern the natural systems around us, so attention must be paid to the designer's role towards his community in its various categories with attention to the psychological aspect of the users and the need to study in depth the modern trends of design and combine them with the design of textile printing.Key words : Bio formation - Hospitalization House

Multiple ecological tactics, like the ones described here, can be imitated to strongly affect these two components in the construction sector. This article provides an in‐depth examination of the literature on biomimicry‐based strategies intended to enhance building designs. This analysis is motivated by the rising need for energy legislation to achieve future local goals and provide a framework for use in Panama. These biomimicry‐based methods have undergone more review and evaluation, and the incorporation of organism‐based design for three of Panama's climate types has been proposed. Therefore, a SWOT analysis assisted in realizing the full potential that biomimicry‐based techniques might have in raising the likelihood of satisfying local and international regulatory standards. In order to design constructions using biomimicry, multidisciplinary collaboration is required. This gives a competitive edge for better‐trained human resources and expands horizons in the conventional construction industry. Finally, the analysis provided here might act as the preliminary step for the additional technical assessment using numerical and experimental procedures. [ABSTRACT FROM AUTHOR]

DarNERcorp is a manually annotated named entity recognition (NER) dataset in the Moroccan dialect, also called Darija. The dataset consists of 65,905 tokens and their corresponding tags according to BIO scheme. 13.8% of the tokens are named entities spanning four categories: person, location, organization, and miscellaneous. The data were scraped from the Moroccan Dialect section of Wikipedia and processed and annotated using open-source libraries and tools. The data are useful for the Arabic natural language processing (NLP) community as they address the lack in dialectal Arabic annotated corpora. This dataset can be used to train and evaluate named entity recognition systems in dialectal and mixed Arabic.

Antimicrobial polypropylene (PP) was developed by plasma functionalization and subsequent immobilization of chitosan (CS)‐chlorhexidine (CHX) nanogels as the bioactive component. Oxygen plasma was used to create a hydrophilic surface monitored by water drop interaction with the fabric surface. CS nanogels were prepared by the ionic gelation method. The characterization of the nanogels was carried out by transmission electron microscopy (TEM) and energy dispersive X‐ray microanalysis (EDX). The functionalized fabric exhibited excellent antimicrobial nature against S. aureus and E. coli microbes. The animal studies involving mice showed that the material exhibited excellent biocompatibility in contact with the skin. There was no evidence of inflammatory cells in the histopathology. This investigation suggests that the fabric has enormous potential as infection‐resistant material in applications such as wet wipes. [ABSTRACT FROM AUTHOR]

Renewable energies are the best solutions to reduce CO2 emissions and supply reliable electricity. This study aims to find the best combination of various components considering economic, environmental, and technical factors together. The most important consideration factors are the limitation of using PV panels due to the land constraints and applying CO2 penalties where diesel generators and the grid are generating electricity. Findings show that providing electricity by hybrid systems would be useful even in the well-provided electricity regions by the grid with the least blackouts. The best combination of the proposed components, including PV, bio generator, diesel generator, batteries, and grid for the case study region where the load demand is 890 kWh/day and peak load is 167.2 kW, would be an off-grid hybrid system including PV, bio generator, diesel generator, and battery. The optimization results show an NPC (present value of the costs of investment and operation of a system over its lifetime) of $1.02 million and a COE (the average cost per capital of useful electricity produced by the system) of 0.188 $/kWh. Finally, due to the showing of the effect of different conditions on the optimization results and making the study usable for other circumstances of the case study region, some sensitivity analyses have been carried out. [ABSTRACT FROM AUTHOR]

Glycogen Synthase Kinase-3 (GSK-3) was recently implicated in the dysregulated biology of acute myeloid leukemia (AML). Low concentrations of GSK-3 inhibitors, SB216763 and BIO, suppressed the proliferation of AML cells with FLT3-ITD as early as 24 h after treatment. BIO was used in subsequent assays since it exhibited higher inhibitory effects than SB216763. BIO-induced G1 cell cycle arrest by regulating the expression of cyclin D2 and p21 in MV4-11 cells, and promoted apoptosis by regulating the cleaved-caspase3 signaling pathways. In vivo assays demonstrated that BIO suppressed tumor growth, while metabolomics assay showed that BIO reduced the levels of ATP and pyruvate in MV4-11 cells suggesting that it inhibited glycolysis. BIO markedly suppressed cell growth and induced apoptosis of AML cells with FLT3-ITD by partially inhibiting glycolysis, suggesting that BIO may be a promising therapeutic candidate for AML. [ABSTRACT FROM AUTHOR]

Trade mark law reflects economic and social trends. With the shift towards an economy based on sustainable development, the rise of environmental awareness among consumers, and the growing popularity of eco-marketing, marks containing indications such as „green”, „eco” or „bio” appear increasingly on the market. Such labels can inform and assist consumers in purchasing products that comply with the eco-requirements, strengthen the competitiveness of producers by promoting the least environmentally damaging products, offering higher quality products, and consequently encouraging both parties to act in an eco-friendly manner. Their registration is possible, but more difficult than for „classic trade marks” submitted for protection before the patent offices. This text is intended to provide an overview of the registration requirements of so-called „green trade marks”. The study mainly used the formal-dogmatic method. Based on an analysis of the European Union Intellectual Property Office practice and the judgments of the Court of Justice of the European Union, authors indicate the applicable interpretation of EU trade mark law. They analyze binding restrictions taking into account the interests of both individual market players and the public. This issue has not yet been commented on by the doctrine. Eco-labels and symbols, which can be used by entities meeting criteria that are defined by certification bodies are outside the scope of this review.

The purpose of current investigation was to explore the scope of integrating an anaerobic digester in a decentralized municipal wastewater treatment plant for in-situ treatment of household waste. The present work intends to identify the potential of sewage sludge and food waste for biogas generation. The study was conducted in lab scale continuous stirred tank reactor having a working volume of 6.5 L at mesophilic temperature. The paper mill sludge was used as inoculum and was stabilised using food waste substrate for initial 50 days in batch mode. Co-digestion of food waste (FW) and bio-flocculated sewage sludge (BFS) was performed using continuous feeding for maintaining OLR of 2.5 gVSL−1D−1at HRT of 4 days for 120 days. 2% FW and 98% BFS (by volume) was feeded in the reactor throughout the experimental duration. The highest VFA accumulation of 1902 mg L−1 were observed and maximum bio-methane yield was found to be 127.05 mLCH4 g−1 VSadded. The pH with current feeding ratio was found stable during the reactor operation without adding external alkalinity source.

The subdigital adhesive pads of Caribbean Anolis lizards are considered to be a key innovation that permits occupation of novel ecological niches. Although previous work has demonstrated that subdigital pad morphology and performance vary with habitat use, such investigations have only considered the macroscale aspects of these structures (e.g. pad area). The morphological agents of attachment, however, are arrays of hair-like fibres (setae) that terminate in an expanded tip (spatula) and have not been examined in a similar manner. Here we examine the setal morphology and setal field configuration of ecologically distinct species of the monophyletic Jamaican Anolis radiation from a functional and ecological perspective. We find that anoles occupying the highest perches possess greater setal densities and smaller spatulae than those exploiting lower perches. This finding is consistent with the concept of contact splitting, whereby subdivision of an adhesive area into smaller and more densely packed fibres results in an increase in adhesive performance. Micromorphological evidence also suggests that the biomechanics of adhesive locomotion may vary between Anolis ecomorphs. Our findings indicate that, in a similar fashion to macroscale features of the subdigital pad, its microstructure may vary in relation to performance and habitat use in Caribbean Anolis. [ABSTRACT FROM AUTHOR]

6-bromoindirubin-3′-oxime (BIO) is a candidate small molecule that effectively modulates Wnt signalling owing to its stable property. The present study investigated the influence of BIO on the odonto/osteogenic differentiation of human dental pulp stem cells (hDPSCs). hDPSCs were treated with 200, 400, or 800 nM BIO, and the effects on hDPSC responses and osteogenic differentiation were assessed. BIO-mediated Wnt activation was confirmed by β-catenin nuclear translocation detected by immunofluorescence staining. BIO attenuated colony formation and cell migration determined by in vitro wound-healing assay. BIO increased early apoptotic cell population evaluated using flow cytometry. For osteogenic induction, BIO promoted alkaline phosphatase (ALP) activity and mineralisation in a dose-dependent manner. ALP, RUNX2, OCN, OSX, ANKH, DMP1, and DSPP mRNA expression were significantly upregulated. The OPG/RANKL expression ratio was also increased. Further, BIO attenuated adipogenic differentiation as demonstrated by decreased lipid accumulation and adipogenic-related gene expression. Bioinformatic analysis of RNA sequencing data from the BIO-treated hDPSCs revealed that BIO modulated pathways related to autophagy and actin cytoskeleton regulation. These findings demonstrated that BIO treatment promoted hDPSC osteogenic differentiation. Therefore, this small molecule is a strong candidate as a bioactive molecule to enhance dentin repair. [ABSTRACT FROM AUTHOR]

Trade mark law reflects economic and social trends. With the shift towards an economy based on sustainable development, the rise of environmental awareness among consumers, and the growing popularity of eco-marketing, marks containing indications such as „green", „eco" or „bio" appear increasingly on the market. Such labels can inform and assist consumers in purchasing products that comply with the eco-requirements, strengthen the competitiveness of producers by promoting the least environmentally damaging products, offering higher quality products, and consequently encouraging both parties to act in an eco-friendly manner. Their registration is possible, but more difficult than for „classic trade marks" submitted for protection before the patent offices. This text is intended to provide an overview of the registration requirements of so-called „green trade marks". The study mainly used the formaldogmatic method. Based on an analysis of the European Union Intellectual Property Office practice and the judgments of the Court of Justice of the European Union, authors indicate the applicable interpretation of EU trade mark law. They analyze binding restrictions taking into account the interests of both individual market players and the public. This issue has not yet been commented on by the doctrine. Eco-labels and symbols, which can be used by entities meeting criteria that are defined by certification bodies are outside the scope of this review. [ABSTRACT FROM AUTHOR]

The problem lies in the research and studying the morphogenic design of the designer is the possibility of studying the inner essence of organic natural phenomena, an important source for contemporary design vision and a new starting point for teaching decorative designs that are formed according to their cells and singularity, as it gives the decorative designer the opportunity to use flat designs and the suggestion of anthropomorphism, which broadens the perceptions of the decorative designer in dealing with vocabulary. Through morphogenic theory and enrichment of design elements and foundations with many plastic variables by employing them with computer graphics in order to update the thought of decorative design in the study of natural phenomena in design, which provided unconventional fields in contemporary design. The research question is determined in the following question: - To what extent does the decorative designer benefit from the morphogenic design and the consequent structural systems and the natural phenomena it contains, on the basis of which the decorative design is formed? Research objectives: The research aims at the graphic employment of the kinetic values ​​of the natural phenomena in the morphogenic art through a group of decorative designs. It proposes new experimental approaches for building the decorative painting in light of the morphogenic system structure. And the production of a set of scientific applications taking advantage of the computer graphic employment of two-dimensional kinematic variables (corals and ice crystals) through morphogenic art. The importance of this research is to emphasize the importance of the design construction of networks through which coral reefs and snow crystals are formed, in a way that gives it the suggestion of anthropomorphism. The genetic system for reformulation to be used as a new contemporary introduction to natural phenomena in the Department of Decorative Designs in the Faculty of Art Education. The research followed the analytical descriptive approach: based on collecting information and analyzing structural systems and actual movement based on the morphogenic theory and its investigation in the genetic code systems to extract the vocabulary, structural system and color group and this is related to the theoretical framework of the study and its use of modern techniques in decorative designs using the computer. The experimental method: Creating innovative designs related to the design construction of the actual movement of natural phenomena (coral reefs and ice crystals) based on morphogenic theory, where the decorative designer achieves the use of flat designs and the suggestion of anthropomorphism, which broadens the perceptions of the decorative designer in dealing with the two-dimensional vocabulary using Photoshop and Adobe illustrator programs .

The singing cicadas (Hemiptera: Cicadidae) of Bulgaria were poorly known. There are published records for 14 species: Cicada orni, Lyristes plebejus, Cicadatra atra, Cicadatra hyalina, Cicadatra persica, Cicadetta montana, Cicadetta mediterranea, Dimissalna dimissa, Oligoglena tibialis, Tympanistalna gastrica, Pagiphora annulata, Saticula coriaria, Tibicina haematodes and Tibicina steveni.Two species from this list were doubtful in the beginning of our study, since Tympanistalna gastrica is distributed in central and southern Portugal and Saticula coriaria is a north African species.We checked three major institutional collections housed in Sofia, Bulgaria: the National Museum of Natural History (SOFM), the Institute of Zoology (ZISB) and the Biology Faculty of Sofia University "St. Kliment Ohridski" (BFUS). We confirmed 11 of the species mentioned in literature, except Cicadetta mediterranea and found two additional species: Cicadatra platyptera and Cicadetta macedonica (the specimens in BFUS were bioacoustically confirmed).Based on this knowledge, we further investigated the singing cicadas of Bulgaria with the use of morphological and bioacoustic methods in the years 2008, 2009, 2010, 2012, 2016, 2018 and 2019. We were not able to confirm the presence of Cicadatra persica and Cicadetta mediterranea, but found three additional species: Cicadetta brevipennis s. lat., Cicadetta cantilatrix and Tettigettula pygmea. Using the bioacoustic methods, we also detected unknown singing patterns, which could belong to three or four additional taxa, which need to be described.The Bulgarian fauna of singing cicadas at the moment consists of 16 confirmed and 3-4 potential species.

This study was conducted to investigate the effect of bacterial bio-fertilization A. chroococcum and P. putide and four levels of compost (0, 1, 2, 3) tons.h-1 on the leaves content of N.P.K elements. The experiment was carried out in one of the greenhouses of the College of Agriculture - University of Al-Qadisiyah during fall season 2018-2019. It designed in accordance with the Randomized Complete Block Design (RCBD) with three replicates in sandy loam soil. The means of treatments were compared with the least significant difference (LSD) at (5)% probability level. The results present that the treatments of A. chroococcum, P. putide and compost at (3) tons.kg-1 significantly increases the leaves content of K.P.K compared to all other treatments in the flowering stage (4.970, 0.5000, and 4.930) mg.kg-1, respectively. This treatment was followed by the effect of the treatment of A. chroococcum and compost at (3) tons.kg-1, which increases the values of all traits except the leaf content of (P). Bio-fertilizer with P. putide + A. chroococcum significantly increases the leaves' content of P.

Copyright of Informacion Tecnica Economica Agraria is the property of Asociacion Interprofesional para el Desarrollo Agrario (AIDA) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The purpose of the report is to provide a terminological device in the field of bio-economy. Scientific and popular definitions for it are emerging and systematized. A historical review is made and the prospects for bio-economics are outlined.

Traditional degumming of bast fibers results in problems such as environmental pollution and inferior fiber quality. For these reasons, biodegumming was considered as a potential process for bast fibers. In biodegumming process, decomposition of noncellulosic components was the pivotal problem. In this manuscript, the bast fiber of Apocynum venetum was processed with combinatorial processing, containing physical, chemical and microbial effect. The structural bio-recalcitrance was analyzed at molecular, supermolecular and morphological level in each stage. The results show that main substance in recalcitrance of Apocynum venetum bast is lignin and hemicellulose. And the protein and wax is also the constituent of bio-recalcitrance. The recalcitrance in the bast tissue can be divided into three layers. The spatial structure and the distribution of the noncellulosic substances also contribute to the recalcitrance. This paper provides directions for pretreatment design to render biomass more amenable to bioprocessing.

Identifying and applying the appropriate method for ecosystem services mapping and assessment is not trivial. To provide guidance in this task, this paper describes the creation of a database for existing studies on mapping and assessing ecosystems and their services, which records relevant information to the ecosystem studies (e.g. methods used, the scale, ecosystem type, ecosystem service categories) and other relevant attributes that need to be considered. This database, therefore, forms the basis for an online ecosystem service ‘methods finder’. Our results provide an overview of the database itself (883 entries until April 2018) and the consultation within the ESMERALDA consortium that shaped its development, as well as providing an overview of the final mapping and assessment methods describing their spatial distribution. This work helps identify the main gaps and opportunities for alignment and development of commonalities in analytical approach amongst the individual Member States. The results illustrate the different conditions, dimensions and geographical contexts in Europe, information that can be used as background to help the development of a flexible methodology for mapping and assessing ecosystem services in Europe. The paper concludes with a discussion on how the typology of methods can be used in initiatives that aim to integrate ecosystems and their services in decision-making and planning. This work highlights some challenges for future activities on mapping and assessment of ecosystem services in the EU.

Bismuth halide oxide with three halogen elements (P‐BiOXs) catalyst was prepared by a facile precipitation method at room temperature only for 30 min. Several measurement technologies were employed to characterise the structures and morphologies of the obtained samples. Coloured Rhodamine B (RhB), methyl orange (MO), methylene blue (MB) and colourless bisphenol A (BPA) were selected to evaluate the photocatalytic activity of the samples. The experimental results showed the P‐BiOXs thin nanoplates exhibited the most excellent photocatalytic activity among the prepared samples for the degradation of MO under visible light illumination. More importantly, the catalyst P‐BiOXs could effectively degradate RhB, MB and BPA. The P‐BiOXs catalyst displayed good photocatalytic stability by the recycling tests. The highly efficient visible light catalytic properties of P‐BiOXs could be due to the high specific surface area, enhanced light‐harvesting ability, the suitable bandgap energy and the lower recombination rate of the photogenerated electrons and holes. [ABSTRACT FROM AUTHOR]

The expansion of the use of safe alternatives such as bio-fertilizers and organic fertilizer programs in fruit seedlings has become part of a system known as clean cultivation because of its many advantages that contribute to improving growth, productivity, quality and production of a safe crop as well as preserving the environment by reducing or avoiding the use of chemical fertilizers, Therefore, this study was conducted to demonstrate the importance of adding biological fertilizer (Gorabac G) in three concentrations (5, 10 and 15 grams. Seedlings-1), liquid organic fertilizer (Compo) in three concentrations (4, 6 and 8 ml-1) and organic fertilizer (Rice residues (in three concentrations (0.5, 1.0 and 1.5 kg. Seedlings-1) in addition to the comparison treatment (without adding any type of fertilizer) in improving the vegetative growth and mineral content of grapefruit seedlings grafted on Sour orange, he biological fertilizer (Gorabac G) used in the study and in particular the concentration was 15 grams. Seedlings-1 had a significant effect in obtaining the highest values for most of the studied traits, as this treatment was significantly superior to the comparison treatment with the traits (leaf content of nitrogen, phosphorus, potassium, iron, chlorophyll, carbohydrates and proteins in addition to the increase in the height and diameter of seedlings), so within similar circumstances the study recommends using This concentration of this vital fertilizer is to get strong, well-growing seedlings. [ABSTRACT FROM AUTHOR]

Objective: GSK-3 has been reported to be upregulated in malignant diseases, including lung cancers, thus suggesting it to be a valid target for cancer treatment. The study elucidates the possible mechanism involved in the ability of GSK-3 inhibitors: BIO and CHIR 98014 to regulate proteins involved in cell death of H1975 lung cancer cells. Results: BIO and CHIR 98014 successfully induced apoptosis at lower concentrations in H1975 cells but not in H460 lung cancer cells. Moreover, increased ROS generation and depolarization of mitochondrial membrane potential were observed in both treatments. Cleavage of caspase-3 was observed in both BIO and CHIR 98014-treated cells after 72 h with monolayer and tumorsphere cell culture models. Conclusions: The use of GSK-3 inhibitors shows promising apoptotic abilities in clinical cancer treatments, particularly for lung cancer cells. This study is the first report to describe the significant apoptotic effects of BIO and CHIR 98014 through multiple mechanisms of H1975 NSCLC that are linked to their proliferative and migratory capacities. [ABSTRACT FROM AUTHOR]

Copyright of Nueva Revista del Pacífico is the property of Universidad de Playa Ancha de Ciencias de la Educacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cuadernos del Centro de Estudios de Diseño y Comunicación is the property of Cuadernos del Centro de Estudios de Diseno y Comunicacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

These Tap casting and powder metallurgy methods used to produce the 45S5 Bioglass. This study revealed that the bioglass modified with 0.2% Y2O3 has about 700% increases in hardness. The modification of bioglass with 0.2% Y2O3 leads to a 44% increase in fracture toughness values. This study revealed that the 0.2% Y2O3 bioglass composition-modification improves the fracture strength by almost 150%. The laboratory histological sections showed that 45S5 bioglass (original composition materials showed nether systemic nor local inflammation with new bone formation at site of implantation. The Y2O3 modified the 45S5 bioglass showed no inflammation reactions as well, but no new bone formation and regeneration was noticed in the adjacent bone tissue.

Dental pulp stem cells (DPSCs) from adult teeth express neural crest (NC) markers together with core transcriptional factors associated with stem cell pluripotency, such as Oct4a, Sox2, c-Myc, Rex1, Stella/Dppa3, Ssea1/Fut4, Lin28 and Nanog. The possibility to boost the natural stemness features of DPSCs by mild methods, that do not involve gene and/or chromatin modification or gene transfection, is highly desirable for cell therapy. Canonical Wnt and Notch are two highly conserved developmental signalling pathways that are involved in NC emergence and stem cell self-renewal. We determined that both pathways coordinate to regulate the expression of core pluripotency and NC factors in DPSCs. Pharmacological inhibition of the Notch pathway for 48 h, by the γ-secretase inhibitor N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT), abolished the expression of NC and core factors. In addition, it induced a silencing of the canonical Wnt signalling and a clear reduction in the stemness potential of DPSCs, as shown by a reduced ability to generate mature, fully differentiated osteoblasts and adipocytes. Conversely, pharmacological activation of the Wnt pathway for 48 h, by either the glycogen synthase kinase 3 beta (GSK3-β) inhibitor 6-bromoindirubin-3´-oxime (BIO) or the human recombinant protein Wnt-3a, not only largely increased the expression of NC and core factors, but also increased the efficiency of DPSCs to differentiate into mature osteoblasts and adipocytes. These results showed that a short preconditioning activation of Wnt/Notch signalling by small molecules and/or recombinant proteins enhanced the stemness and potency of DPSCs in culture, which could be useful for optimising the therapeutic use of these and other tissue-specific stem cells.

In today’s economy increased attention is given towards re-using of available resources and using of resources which are re-generable, to evaluate and reduce the impact on the environment. For the polymer industry, the development of alternative and renewable raw materials represents an essential task. The study evaluates the different choices of unsaturated polyester resins (UPR) for production of centrifugally-cast glass reinforced pipe (cc-GRP) systems. The environmental impacts of three types of resin were evaluated and compared. The resins are: UPR standard, UPR containing recycled PET material (rPET-UPR) and UPR containing bio-sourced material (BIO-UPR). The analysis focuses on comparing the variations in environmental indicators caused by resin selection for three increasingly complex product layers (Base plate of cc-GRP shaft, cc-GRP Shaft and 1km cc-GRP Pipe-system). The study equally provides an insight onto R&D and LCA collaboration across the supply-chain. One of the main challenges in LCA today is using specific data from the suppliers instead of generic data. The paper indicates how LCA tools and established R&D processes can be employed to transfer LCA calculations across the supply-chain. BIO-UPR and rPET-UPR are alternatives which are realistic in terms of costs and which ensure the required quality for the manufactured products. rPET-UPR can be used for production of complete pipe systems, with positive environmental indicators. Mechanical proprieties of BIO-UPR restrict its usability and use of this resin presents similarities with the debate regarding use of bio-diesel.

A mysterious female phorid fly, known for many years to be associated with fungal sporophores ("mushrooms") is identified as Megaselia marquezi Hartop et al. 2015. Male and female flies were collected emerging from the fungus Psathyrella candolleana (Fr.) Maire, and females were observed swarming over the sporophores.

We investigated the efficacy of the traditional herbal extract 6-bromoindirubin-3′-oxime (BIO) against lipopolysaccharide (LPS)-induced mastitis in mice and inflammatory signaling in mouse mammary epithelial cells (MMECs). In vivo, breast inflammation scores and enzyme-linked immunosorbent assay (ELISA) detection of pro-inflammatory factor expression were used to assess the effect of BIO against mastitis. In vitro, the effects of BIO on LPS-induced changes in the expression levels of pro-inflammatory factors, anti-inflammatory cytokines, and signaling factors of the toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) and TLR4/mitogen-activated protein kinase (MAPK) pathways were examined by qRT-PCR and ELISA. In LPS-injected mice, BIO pretreatment downregulated the expression of the pro-inflammatory factors interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, and myeloperoxidase (MPO) in mammary glands and reduced inflammatory lesions in breast tissue. In MMECs, BIO pretreatment downregulated the LPS-induced expression of IL-1β, IL-6, and TNF-α. Further, BIO inhibited both the expression and phosphorylation of TLR4/NF-κB and TLR4/MAPK signaling factors. Thus, BIO downregulates IL-6, IL-1β, TNF-α, and MPO expression, upregulates IL-10 expression, and suppresses LPS-induced inflammation by inhibiting the TLR4/NF-κB and TLR4/MAPK pathways. BIO may be a potential treatment agent for mastitis and other inflammatory diseases. [ABSTRACT FROM AUTHOR]

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In this work, a promising strategy was established to regulate the coordination environment of Bi active sites through metal atom doping. Interestingly, the doped Co in BiO quantum dots (QDs) are atomically dispersed in the second coordination shell, and can promote the hybridization and redistribution of atomic orbitals, thus improving the interaction with C 2p orbital in CO 2 molecules. The Co single atom located at the secondary coordination shell changes the work function of BiO QDs, thereby facilitating the transfer of photogenerated electrons from Co to Bi active sites, and thus more long-lived electrons can take part in the CO 2 reduction reaction. Additionally, the free energy calculations demonstrate that the existence of Co single atoms in secondary coordination environment is conducive to reduce the formation energy barriers as well as boost the stability of the intermediate *COOH, thus promoting the catalytic performance towards CO 2 reduction. [Display omitted] • For the first time Co single atom act as the coordination atom in secondary coordination environment. • Co single atoms contribute electrons to neighboring Bi atoms, thus increasing the electron density of Bi active sites. • The adsorption and activation capacity of CO 2 molecules at Bi active sites are improved. • The stability of intermediate *COOH has been greatly improved during the catalytic reaction process. [ABSTRACT FROM AUTHOR]

This paper deals to design and investigated two proposed loop antenna for pill shaped bio-implants objects such as wireless capsule endoscopy. In additional it’s help in developing an understanding of how the fields decay with distance. The first proposed loop antenna is the planar printed square loop antenna with outer dimensions 9 mm and inner dimension 0.45 mm, 6 turns, width 0.5 mm and 0.25 mm of space which can be easily integrated with a system-on-chip technology. The second proposed loop antenna is the solenoidal loop antenna where the solenoid had 9 turns, a pitch of 1 mm and a radius of 5 mm and can be easily wound in the form of a coil and encased within the pill shaped object. For both antennas the electromagnetic field was solved at 1MHz. From the radiation patterns results it can be observe that the surrounding pattern gain around the antennas is constant and conform the omnidirectional pattern associated to such loop antennas that fit the capsule endoscopy randomly movement within the human body in different directions. The design simulations and results are performed and validated by using commercial High Frequency Structure HFSS software.

In this study five compositions of CoNiAl alloy with fixed Al content were prepaid to investigate the effect of chemical composition on the microstructure and phase volume fractions. It was found that by increasing Co the volume fraction of β phase increases and by increasing the β phase the grain size will be increased. This increase will be reflected on increasing the hardness of this alloy. Further investigations for the corrosion resistance in simulated body environment were done. It was found that phase volume fractions increased corrosion rate by increasing the volume fraction of β phase.