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1. Severe postoperative morbidity after left colectomy for sigmoid diverticulitis without splenic flexure mobilization. Results of a multicenter cohort study with propensity score analysis

Author

Barraud, Alexis, Sabbagh, Charles, Beyer-Berjot, Laura, Ouaissi, Mehdi, Zerbib, Philippe, Bridoux, Valérie, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, Godet, Camille, Eid, Yassine, Duchalais, Emilie, Lakkis, Zaher, Cotte, Eddy, Laforest, Anaïs, Defourneaux, Véronique, Maggiori, Léon, Rebibo, Lionel, Christou, Niki, Talal, Ali, Mege, Diane, Bonnamy, Cécile, Germain, Adeline, Mauvais, François, Tresallet, Christophe, Roudie, Jean, Laurent, Alexis, Trilling, Bertrand, Bertrand, Martin, Massalou, Damien, Romain, Benoit, Tranchart, Hadrien, Pellegrin, Alexandra, Briant, Anais R., Parienti, Jean Jacques, and Alves, Arnaud

Published
2024
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2. Risk factors for emergency surgery for diverticulitis: A retrospective multicentric French study at 41 hospitals

Author

Jeanne, Dembinski, Gillet, Julien, Hamy, Antoine, Lahmidi, Amine, Sebbagh, Mohamed, Bres, Antoine, Girard, Nicolas, Desjouis, Aurélie, Ainseba, Nadjib, Epailly, Julien, Huysman, Fabienne, Dezeustre, Maud, Doussot, Alexandre, Turco, Célia, Bourrhis, Diane, Godet, Camille, Finocchi, Morgane, Marion, Yoan, Lebreton, Gil, Benard, Flavie, Pineau, Elodie, Bouvier, Véronique, Ortega-Deballon, Pablo, Moreno-Lopez, Nathan, Rat, Patrick, Makar, Bassem, Fara, Paola, Pompilio, Marc, Hertault, Hugo, Guezennec, Corentin, Saida, Habchi, Brinza, Alexandre, Plard, Laurent, Ailhaud, Antoine, Gutierrez, Léa, Venchiarutti, Vincent, Faucheron, Jean-Luc, Morin, Bertrand, Pech de la Clause, Bertrand, Voitellier, Eglantine, Gagnat, Guillaume, Noiret, Barbara, Laroye, Constance, Piessen, Guillaume, Lécolle, Katia, Robert, Jean, Nzamushelepanmabla, Engel, Perrine, Mathonnet, Muriel, Rodriguez, Cyprien, Makki, Ammar, Couchard, Anne-Cécile, Duramé, François, Marceau, Cécile, Paquet, Jean-Christophe, Kepenekian, Vahan, Passot, Guillaume, Glehen ; Ninon Wallach, Olivier, Mohkam, Kayvan, Blanc, Marie-Caroline, Berdah, Stéphane, Aubert, Mathilde, Ayav, Ahmet, Chanty, Hervé, Didier, Alexandre, Vigneron, Estelle, Périard, Noémie, Thaumoux, Marie, Grenouilloux, Océane, Fall, Seila, Thomareis, Sophoclis, Marsollier, Chloé, Prud’homme, Michel, Antonopulos, Christos, Msika, Simon, Monsinjon, Marie, Giacca, Massimo, Cazelles, Antoine, Karoui, Mehdi, Malerba, Valentina, Dagher, Ibrahim, de Angelis, Nicola, Brunetti, Francesco, Ahmed, Omar, Ferraz, Jean-Marc, Ramjaun, Yassir, Denet, Christine, Fuchs, Basile, Pietrasz, Daniel, Raimbert, Pénélope, Benedetti, Juliette, Coton, Chloé, Corte, Hélène, Medrignac, Aude, Chavrier, Daphné, Girard, Robin, Berthelot, Julia, Monge, Matthieu, Papet, Eloïse, Pinson, Jean, Dolbeau, Elise, Tuech, Jean-Jacques, Chautard, Julien, Boullier, Mathilde, Goujard, François, Perrot, Laurent, Loge, Ludovic, Petiot, Jean-Michel, Manfredelli, Simone, Charleux-Muller, Diane, Sauvinet, Guillaume, Bertin, Jean-Baptiste, Vincent, Louis, Simeu, Blandine, Delhorme, Jean-Baptiste, Brigand, Cécile, Rohr, Serge, Bouchet, Manon, Duffas, Jean-Pierre, Ghouti, Laurent, Philis, Antoine, Portier, Guillaume, Karam, Elias, Michot, Nicolas, Artus, Alice, Mauny, Emilien, Bourbao-Tournois, Céline, Barbin, Hugo, Thiery, Julien, Sabbagh, Charles, Beyer-Berjot, Laura, Ouaissi, Mehdi, Zerbib, Philippe, Valérie, Bridoux, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, Eid, Yassine, Duchalais, Emilie, Lakkis, Zaher, Cotte, Eddy, Laforest, Anaïs, Desfourneaux-Denis, Véronique, Maggiori, Léon, Rebibo, Lionel, Niki, Christou, Talal, Ali, Mege, Diane, Bonnamy, Cécile, Germain, Adeline, Mauvais, François, Tresallet, Christophe, Roudie, Jean, Laurent, Alexis, Trilling, Bertrand, Bertrand, Martin, Massalou, Damien, Romain, Benoit, Tranchart, Hadrien, Pellegrin, Alexandra, Dejardin, Olivier, and Alves, Arnaud

Published
2024
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6. Nonmetastatic ypt0 rectal cancer after neoadjuvant treatment and total mesorectal excision: Lessons from a retrospective multicentric cohort of 383 patients

Author

Collard, Maxime K., Rullier, Eric, Panis, Yves, Manceau, Gilles, Benoist, Stéphane, Tuech, Jean-Jacques, Alves, Arnaud, Laforest, Anais, Mege, Diane, Cazelles, Antoine, Beyer-Berjot, Laura, Christou, Niki, Cotte, Eddy, Lakkis, Zaher, O’Connell, Lauren, Parc, Yann, Piessen, Guillaume, and Lefevre, Jérémie H.

Published
2022
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8. Three-year outcome of local injection of autologous stromal vascular fraction cells and microfat in refractory perianal fistulas of Crohn’s disease

Author

Guillo, Lucas, Grimaud, Fanny, Houser, Fanny, Prost, Caroline, Jouve, Elisabeth, Philandrianos, Cécile, Abellan, Maxime, Veran, Julie, Visee, Carine, Beyer-Berjot, Laura, Desjeux, Ariadne, Dignat-George, Françoise, Leone, Marc, Grimaud, Jean-Charles, Sabatier, Florence, Serrero, Mélanie, and Magalon, Jérémy

Published
2022
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9. Benefit of a flash dose of corticosteroids in digestive surgical oncology: a multicenter, randomized, double blind, placebo-controlled trial (CORTIFRENCH)

Author

Magnin, Joséphine, Fournel, Isabelle, Doussot, Alexandre, Régimbeau, Jean-Marc, Zerbib, Philippe, Piessen, Guillaume, Beyer-Berjot, Laura, Deguelte, Sophie, Lakkis, Zaher, Schwarz, Lilian, Orry, David, Ayav, Ahmet, Muscari, Fabrice, Mauvais, François, Passot, Guillaume, Trelles, Nelson, Venara, Aurélien, Benoist, Stéphane, Messager, Mathieu, Fuks, David, Borraccino, Baptiste, Trésallet, Christophe, Valverde, Alain, Souche, François-Régis, Herrero, Astrid, Gaujoux, Sébastien, Lefevre, Jérémie, Bourredjem, Abderrahmane, Cransac, Amélie, and Ortega-Deballon, Pablo

Published
2022
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11. Link between postoperative ileus and anastomotic leakage: A structural equation modelling approach

Author

Abderrazak, M., Abolo, H., Abras, N., Aissou, M., Albertini, S., Alfonsi, P., Andre, A., Arimont, J.M., Arnalsteen, L., Atger, J., Attias, A., Aumont, O., Auvray, S., Bachmann, R., Barabino, G., Barsotti, P., Beauchesne, B., Beaupel, N., Beliard, A., Bellouard, A., Beloeil, H., Ben Salem, F., Benhamou, A., Billard, V., Binhas, M., Binot, D., Blache, J.L., Blet, A., Bongiovanni, J.P., Bonnal, A., Bonnet, M., Boret, H., Bossard, A.E., Bothereau, H., Bouarroudj, N., Bouayed, A., Bouchard, F., Boumadani, M., Bousquet, M., Bouygues, V., Bozio, G., Brek, A., Cadi, P., Caillon, P., Camerlo, A., Capito, C., Cardin, J.L., Castiglioni, M., Catinois, M.L., Cattan, P., Chambrier, C., Chambrier, G., Chapuis, O., Chauvin, M., Chokairi, S., Chopin Laly, X., Collange, V., Cotte, E., Cuellar, E., D'errico, E., Dahmani, S., Danan, M., De La Fontaine, C., De Wailly, P., Degauque, C., Delacoste, F., Denet, C., Denost, Q., Desaint, P., Descamps, E., Desfourneaux., V, Desmet, J., Desolneux, G., Dileon, S., Dolbeau, J.B., Douard, R., Dufour, F., Dupont-Bierre, E., Dupré, A., Entremont, A., Faucheron, J.L., Fernoux, P., Figuet, S., Finianos, A., Flamein, R., Fletcher, D., Fontes, J.P., Fourn, E., Gergeanu, S., Germain, A., Gignoux, B., Goater, P., Gres., P, Grigoroiu, M., Grillo, P., Guignard, B., Guinier, D., Guiot, J.L., Gutton, C., Hadjadj, H., Hail, K., Hausermann, M.H., Hennequin, S., Homsy-Hubert, B., Jambet, S., Janecki, T., Jannier-Guillou, V., Jaspart, J., Joly, F., Joris, J., Journe, F., Kattou, F., Kemoun, G., Khalaf, M., Klack, F., Kothonidis, K., Kurdi, O., Laforest, A., Lamblin, A., Lammens, S., Laporte, S., Launay-Savary, M.V., Le Maho, A.L., Lemée, J.M., Leonard, D., Leporrier, J., Lorin, J.L., Magne, E., Maisonnette, F., Malherbe, V., Manceau, G., Mariani, P., Massalou, D., Massard, J.L., Mauvais, F., Mbuyamba, J., Mbuyamba Katapile, J., Mehila, T., Meillat, H., Mergui, C., Michaud, P., Milou, F., Mirre, F., Mor Martinez, C., Mouchon, S., Mouilhade, F., Nguyen, Y.L., Ostermann Bucher, S., Page, M., Parent, S., Payen, A.L., Pedicone, R., Peluchon, P., Pichot-Delahaye, V., Piquard, A., Pirlet, I., Plard, L., Poiblanc, M., Poinas, G., Poincenot, J., Ponchel, C., Pontallier, A., Pop, R., Potiron, E., Proske, J.M., Prunet, B., Ras, E., Raspado, O., Raux, M., Regimbeau, J.M., Remue, C., Renacco, F., Riboud, R., Richard-Payen, A.L., Rio, D., Sage, M., Sage, P.Y., Saint Denis, M., Salaun, P., Samyn, B., Sbai Idrissi, M., Schmitt, G., Secq, E., Seddiki, A., Sens, N., Sirieix, D., Siriser, F., Tarcea, M., Tavernier, M., Tete, B., Theissen-Laval, O., Thevenot, A., Thievenaz, R., Vacher, B., Verhaeghe, R., Verrier, J.F., Vieuille, C., Voilin, C., Vuagnat, C., Zaepfel, S., Venara, Aurélien, Hamel, Jean-Francois, Beyer-Berjot, Laura, Vignaud, Timothée, and Slim, Karem

Published
2021
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12. Advanced colonic cancer with clinically suspected bladder invasion: Outcomes and prognosis from a multicentric study of 117 patients from the FRENCH research group

Author

Arfa, Sara, Dumont, Paul-Noël, Boullenois, Hortense, Fuks, David, Ouaissi, Mehdi, Benhaim, Leonor, Selvy, Marie, Tuech, Jean-Jacques, Lakkis, Zaher, Lupinacci, Renato, Epin, Antoine, Deguelte, Sophie, Passot, Guillaume, Trilling, Bertrand, Jarlot-Gas, Cécile, Mathonnet, Muriel, Moszkowicz, David, M’Harzi, Leila, Beyer Berjot, Laura, Vuillermet, Cindy, Meillat, Hélène, Manceau, Gilles, Creavin, Ben, Eveno, Clarisse, Benoist, Stéphane, Parc, Yann, and Lefevre, Jérémie H.

Published
2020
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13. Risk factors for emergency surgery for diverticulitis: A retrospective multicentric French study at 41 hospitals.

Author

Godet, Camille, Sabbagh, Charles, Beyer-Berjot, Laura, Ouaissi, Mehdi, Zerbib, Philippe, Valérie, Bridoux, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, and Chautard, Julien

Abstract

The observed increase in the incidence of complicated diverticulitis may lead to the performance of more emergency surgeries. This study aimed to assess the rate and risk factors of emergency surgery for sigmoid diverticulitis. The primary outcomes were the rate of emergency surgery for sigmoid diverticulitis and its associated risk factors. The urgent or elective nature of the surgical intervention was provided by the surgeon and in accordance with the indication for surgical treatment. A mixed logistic regression with a random intercept after multiple imputations by the chained equation was performed to consider the influence of missing data on the results. Between 2010 and 2021, 6,867 patients underwent surgery for sigmoid diverticulitis in the participating centers, of which one-third (n = 2317) were emergency cases. In multivariate regression analysis with multiple imputation by chained equation, increasing age, body mass index <18.5 kg/m2, neurologic and pulmonary comorbidities, use of anticoagulant drugs, immunocompromised status, and first attack of sigmoid diverticulitis were independent risk factors for emergency surgery. The likelihood of emergency surgery was significantly more frequent after national guidelines, which were implemented in 2017, only in patients with a history of sigmoid diverticulitis attacks. The present study highlights a high rate (33%) of emergency surgery for sigmoid diverticulitis in France, which was significantly associated with patient features and the first attack of diverticulitis. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Surgical management of obstructive right-sided colon cancer at a national level results of a multicenter study of the French Surgical Association in 776 patients

Author

Berger, Anne, Ouaissi, Mehdi, Codjia, Tatiana, Dazza, Marie, Gagnat, Guillaume, Hamel, Servane, Mallet, Laure, Martre, Paul, Philouze, Guillaume, Roussel, Edouard, Tortajada, Pauline, Dumaine, Anne Stéphanie, Heyd, Bruno, Lakkis, Zaher, Paquette, Brice, de' Angelis, Nicola, Esposito, Francesco, Lizzi, Vincenzo, Michot, Nicolas, Denost, Quentin, Tresallet, Christophe, Tetard, Oriana, Sabbagh, Charles, Rivier, Pauline, Fayssal, Elie, Collard, Maxime, Moszkowicz, David, Peschaud, Frederique, Etienne, Jean Charles, loge, Ludovic, Beyer-Berjot, Laura, Bege, Thierry, Corte, Hélène, Bonnet, Julien, D'Annunzio, Elsa, Humeau, Marine, Issard, Julien, Munoz, Nicolas, Abba, Julio, Jafar, Yaqoub, Lacaze, Laurence, Sage, Pierre Yves, Susoko, Lilija, Trilling, Bertrand, Arvieux, Catherine, Mauvais, François, Severino, Béatrice Ulloa, Pitel, Sophie, Vauchaussade de Chaumont, Arthus, Badic, Bogdan, Blanc, Benjamin, Bert, Marine, Rat, Paul, Ortega-Deballon, Pablo, Chau, Amélie, Dejeante, Clémentine, Mariette, Christophe, Piessen, Guillaume, Grégoire, Emilie, Alfarai, Abdallah, Lefèvre, Jérémie, Cabau, Magali, David, Anaelle, Kadoche, Deborah, Dufour, Fanny, Goin, Géraldine, Goudard, Yvain, Pauleau, Ghislain, Sockeel, Philippe, De la Villeon, Bruno, Pautrat, Karine, Eveno, Clarisse, Brouquet, Antoine, Couchard, Anne Cécile, Balbo, Gregoire, Mabrut, Jean Yves, Bellinger, Justine, Bertrand, Martin, Aumont, Aurélie, Duchalais, Emilie, Messière Adrien Tranchart, Anne-Sophie, Cazauran, Jean-Baptiste, Pichot-Delahaye, Virginie, Dubuisson, Vincent, Maggiori, Leon, Boumediene, Bilem Djawad, Fuks, David, Kahn, Xavier, Huart, Eve, Catheline, Jean Marc, Lailler, Grégory, Baraket, Oussama, Baque, Patrick, Diaz de Cerio, Jean Marie, Bernard Maes, Philippe Mariol, Fernoux, Philippe, Guillem, Philippe, Chatelain, Eric, de Saint Roman, Charlotte, Fixot, Kévin, Mege, Diane, Manceau, Gilles, Bridoux, Valérie, Venara, Aurélien, Voron, Thibault, Brunetti, Francesco, Sielezneff, Igor, and Karoui, Mehdi

Published
2018
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19. Iatrogenic ureteral injury during colorectal surgery has a significant impact on patient outcomes: a French multicentric retrospective cohort study

Author

Sérénon, Victor, Rouanet, Philippe, Charleux-Muller, Diane, Eveno, Clarisse, Poirot, Karine, Trilling, Bertrand, Benoist, Stéphane, Manceau, Gilles, Panis, Yves, Alves, Arnaud, Kartheuser, Alex, Venara, Aurélien, Pocard, Marc, Sabbagh, Charles, Laforest, Anaïs, Lakkis, Zaher, Badic, Bogdan, Chau, Amélie, Christou, Niki, Beyer-Berjot, Laura, Dumont, Frederic, Germain, Adeline, Valverde, Alain, Duchalais, Emilie, Ouaissi, Mehdi, Benhaim, Leonor, Collard, Maxime, Tuech, Jean‐jacques, Buscail, Etienne, Mege, Diane, Régimbeau, Jean-Marc, Aix-Marseille Université - École de médecine (AMU SMPM MED), Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU)-Aix Marseille Université (AMU), CRLC Val d'Aurelle-Paul Lamarque, CRLCC Val d'Aurelle - Paul Lamarque, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), CHU Grenoble, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Aix-Marseille Université - Faculté de médecine (AMU MED), Aix Marseille Université (AMU), Service de Chirurgie Viscérale et Digestive [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Unité de recherche interdisciplinaire pour la prévention et le traitement des cancers (ANTICIPE), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN)-Centre Régional de Lutte contre le Cancer François Baclesse [Caen] (UNICANCER/CRLC), Normandie Université (NU)-UNICANCER-Tumorothèque de Caen Basse-Normandie (TCBN)-UNICANCER-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Caen Normandie - UFR Santé (UNICAEN Santé), Normandie Université (NU)-Normandie Université (NU), Université Catholique de Louvain = Catholic University of Louvain (UCL), Hémodynamique, Interaction Fibrose et Invasivité tumorales Hépatiques (HIFIH), Université d'Angers (UA), CArcinose Péritoine Paris-Technologies (ex-CART) (CAP Paris-Tech (UMR_S_1275)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Chirurgie digestive [CHU Amiens], CHU Amiens-Picardie, Simplification des soins chez les patients complexes - UR UPJV 7518 (SSPC), Université de Picardie Jules Verne (UPJV), Sorbonne Université (SU), CHU Saint-Antoine [AP-HP], Service d'Oncologie Médicale [CHRU Besançon], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire de Traitement de l'Information Medicale (LaTIM), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), Contrôle de l’Activation Cellulaire, Progression Tumorale et Résistance thérapeutique (CAPTuR), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Service de Chirurgie digestive, endocrinienne et générale [CHU Limoges], CHU Limoges, and The French Research Group of Rectal Cancer Surgery = Groupe de Recherche en Chirurgie du Rectum (GRECCAR)

Subjects
ureteral injury, colorectal surgery, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, chemotherapy, ureteral stent
Abstract

International audience; Aim: The long-term urological sequelae after iatrogenic ureteral injury (IUI) during colorectal surgery are not clearly known. The aims of this work were to report the incidence of IUI and to analyse the long-term consequences of urological late complications and their impact on oncological results of IUI occurring during colorectal surgery through a French multicentric experience (GRECCAR group).Method: All the patients who presented with IUI during colorectal surgery between 2010 and 2019 were retrospectively included. Patients with ureteral involvement needing en bloc resection, delayed ureteral stricture or noncolorectal surgery were not considered.Results: A total of 202 patients (93 men, mean age 63 ± 14 years) were identified in 29 centres, corresponding to 0.32% of colorectal surgeries (n = 63 562). Index colorectal surgery was mainly oncological (n = 130, 64%). IUI was diagnosed postoperatively in 112 patients (55%) after a mean delay of 11 ± 9 days. Intraoperative diagnosis of IUI was significantly associated with shorter length of stay (21 ± 22 days vs. 34 ± 22 days, p < 0.0001), lower rates of postoperative hydronephrosis (2% vs. 10%, p = 0.04), anastomotic complication (7% vs. 22.5%, p = 0.002) and thromboembolic event (0% vs. 6%, p = 0.02) than postoperative diagnosis of IUI. Delayed chemotherapy because of IUI was reported in 27% of patients. At the end of the follow-up [3 ± 2.6 years (1 month-13 years)], 72 patients presented with urological sequalae (36%). Six patients (3%) required a nephrectomy.Conclusion: IUI during colorectal surgery has few consequences for the patients if recognized early. Long-term urological sequelae can occur in a third of patients. IUI may affect oncological outcomes in colorectal surgery by delaying adjuvant chemotherapy, especially when the ureteral injury is not diagnosed peroperatively.

Published
2023

20. Penetrating Crohn Disease Is Not Associated With a Higher Risk of Recurrence After Surgery: A Prospective Nationwide Cohort Conducted by the Getaid Chirurgie Group

Author

Maggiori, Léon, Brouquet, Antoine, Zerbib, Philippe, Lefevre, Jérémie H., Denost, Quentin, Germain, Adeline, Cotte, Eddy, Beyer-Berjot, Laura, Munoz-Bongrand, Nicolas, Desfourneaux, Véronique, Rahili, Amine, Duffas, Jean-Pierre, Pautrat, Karine, Denet, Christine, Bridoux, Valérie, Meurette, Guillaume, Faucheron, Jean-Luc, Loriau, Jérome, Souche, Regis, Vicaut, Eric, Panis, Yves, and Benoist, Stéphane

Published
2019
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25. Anti-TNF Therapy Is Associated With an Increased Risk of Postoperative Morbidity After Surgery for Ileocolonic Crohn Disease: Results of a Prospective Nationwide Cohort

Author

Brouquet, Antoine, Maggiori, Léon, Zerbib, Philippe, Lefevre, Jérémie H., Denost, Quentin, Germain, Adeline, Cotte, Eddy, Beyer-Berjot, Laura, Munoz-Bongrand, Nicolas, Desfourneaux, Véronique, Rahili, Amine, Duffas, Jean-Pierre, Pautrat, Karine, Denet, Christine, Bridoux, Valérie, Meurette, Guillaume, Faucheron, Jean-Luc, Loriau, Jérome, Guillon, Françoise, Vicaut, Eric, Benoist, Stéphane, and Panis, Yves

Published
2018
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29. Additional file 1 of Benefit of a flash dose of corticosteroids in digestive surgical oncology: a multicenter, randomized, double blind, placebo-controlled trial (CORTIFRENCH)

Author

Magnin, Joséphine, Fournel, Isabelle, Doussot, Alexandre, Régimbeau, Jean-Marc, Zerbib, Philippe, Piessen, Guillaume, Beyer-Berjot, Laura, Deguelte, Sophie, Lakkis, Zaher, Schwarz, Lilian, Orry, David, Ayav, Ahmet, Muscari, Fabrice, Mauvais, François, Passot, Guillaume, Trelles, Nelson, Venara, Aurélien, Benoist, Stéphane, Messager, Mathieu, Fuks, David, Borraccino, Baptiste, Trésallet, Christophe, Valverde, Alain, Souche, François-Régis, Herrero, Astrid, Gaujoux, Sébastien, Lefevre, Jérémie, Bourredjem, Abderrahmane, Cransac, Amélie, and Ortega-Deballon, Pablo

Abstract

Additional file 1. CORTIFRENCH Trial: List of investigators.

Published
2022
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30. Impact of the Ileal Microbiota on Surgical Site Infections in Crohn's Disease: A Nationwide Prospective Cohort

Author

Julien, Clément, Anakok, Emré, Treton, Xavier, Nachury, Maria, Nancey, Stéphane, Buisson, Anthony, Fumery, Mathurin, Filippi, Jérôme, Maggiori, Léon, Panis, Yves, Zerbib, Philippe, François, Yves, Dubois, Anne, Sabbagh, Charles, Rahili, Amine, Seksik, Philippe, Allez, Matthieu, Lefevre, Jérémie, Cattan, Pierre, Chirica, Mircea, Munoz-Bongrand, Nicolas, Corte, Hélène, Beaupel, Nathan, Catry, Jonathan, Gornet, Jean-Marc, Baudry, Clotilde, Lourenco, Nelson, Maillet, Mariane, Tran-Minh, My-Linh, Chardiny, Victor, Bonnet, Joelle, Chedouba, Leila, Nisard, Andrée, Beaugerie, Laurent, Bourrier, Anne, Nion-Larmurier, Isabelle, Kirchgesner, Julien, Landman, Cécilia, Quevrain, Elodie, Brot, Loic, Chafai, Najim, Parc, Yann, Debove, Clothilde, Svreck, Magali, Vincent, Camille, Guedj, Nathalie, Ferron, Marianne, Bouhnik, Yoram, Corcos, Olivier, Stefanescu, Carmen, Khabil, Sarah, Marteau, Philippe, Dray, Xavier, Chaput, Ulrika, Bommelaer, Gilles, Goutte, Marion, Denizot, Jérémie, Barnich, Nicolas, Coban, Dilek, Desreumaux, Pierre, Pariente, Benjamin, Sommeville, Coralie, Dupas, Jean-Louis, Loreau, Julien, Brazier, Franck, Chatelain, Denis, Attencourt, Christophe, Leconte, Martine, Boschetti, Gilles, Flourié, Bernard, Cotte, Eddy, Charlois, Anne-Laure, Falgon, Peggy, Hadjisavvas, Helena, Moussata, Driffa, Chauvenet, Marion, Boyer, Sarah, Hebuterne, Xavier, Arab, Nadia, Barhoumi, Raja, Hofmann, Paul, Le Corff, Sylvain, Bonnet, Anna, Beyer-Berjot, Laura, Sokol, Harry, Service de Chirurgie viscérale et disgestive, Hôpital Nord [CHU - APHM], Laboratoire de Probabilités, Statistique et Modélisation (LPSM (UMR_8001)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Service de Gastroentérologie [Hôpital Beaujon], Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institute for Translational Research in Inflammation - U 1286 (INFINITE (Ex-Liric)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Service d'Hépatologie Gastro-entérologie [CHU Clermont-Ferrand], CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Service d'Hépato Gastroenterologie [CHU Amiens-Picardie], CHU Amiens-Picardie, Périnatalité et Risques Toxiques - UMR INERIS_I 1 (PERITOX), Institut National de l'Environnement Industriel et des Risques (INERIS)-Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Centre Hospitalier Universitaire de Nice (CHU Nice), Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Chirurgie colorectale [Hôpital Beaujon], Hôpital Claude Huriez [Lille], CHU Lille, Service de chirurgie digestive et oncologique [Centre Hôspitalier Lyon Sud], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), CHU Clermont-Ferrand, Chirurgie digestive [CHU Amiens], Simplification des soins chez les patients complexes - UR UPJV 7518 (SSPC), Université de Picardie Jules Verne (UPJV), Paris Center for Microbiome Medicine (FHU PaCeMM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Grenoble, Hôpital Lariboisière-Fernand-Widal [APHP], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516 (CHIMERE), Servcie Hépato-gastroentérolgie et Nutrition clinique [CHU Nice], Institut Polytechnique de Paris (IP Paris), Communications, Images et Traitement de l'Information (TSP - CITI), Institut Mines-Télécom [Paris] (IMT)-Télécom SudParis (TSP), Traitement de l'Information Pour Images et Communications (TIPIC-SAMOVAR), Services répartis, Architectures, MOdélisation, Validation, Administration des Réseaux (SAMOVAR), Institut Mines-Télécom [Paris] (IMT)-Télécom SudParis (TSP)-Institut Mines-Télécom [Paris] (IMT)-Télécom SudParis (TSP), Laboratoire de Biomécanique Appliquée (LBA UMR T24), Aix Marseille Université (AMU)-Université Gustave Eiffel, MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), and AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
Crohn’s disease, Crohn Disease, Ileum, Gastroenterology, Humans, Surgical Wound Infection, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, General Medicine, Gut microbiota, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, Prospective Studies, Prediction, Gastrointestinal Microbiome
Abstract

Background and Aims Surgery is performed in 50–70% of Crohn’s disease [CD] patients, and its main risk is surgical site infection [SSI]. The microbiota has been extensively assessed in CD but not as a potential risk factor for septic morbidity. The objective of this study was to assess the impact of the gut microbiota on SSI in CD. Methods We used the multicentric REMIND prospective cohort to identify all patients who experienced SSI after ileocolonic resection for CD, defined as any postoperative local septic complication within 90 days after surgery: wound abscess, intra-abdominal collection, anastomotic leakage or enterocutaneous fistula. The mucosa-associated microbiota of the ileal resection specimen was analysed by 16S gene sequencing in 149 patients. The variable selection and prediction were performed with random forests [R package VSURF] on clinical and microbiotal data. The criterion of performance that we considered was the area under the Receiver Operating Characteristic [ROC] curve [AUC]. Results SSI occurred in 24 patients [16.1%], including 15 patients [10.1%] with major morbidity. There were no significant differences between patients with or without SSI regarding alpha and beta diversity. The top selected variables for the prediction of SSI were all microbiota-related. The maximum AUC [0.796] was obtained with a model including 14 genera, but an AUC of 0.78 had already been obtained with a model including only six genera [Hungatella, Epulopiscium, Fusobacterium, Ruminococcaceae_ucg_009, Actinomyces and Ralstonia]. Conclusion The gut microbiota has the potential to predict SSI after ileocolonic resection for CD. It might play a role in this frequent postoperative complication.

Published
2021

31. Surgical Management of Retrorectal Tumors: A French Multicentric Experience of 270 Consecutives Cases

Author

Aubert, Mathilde, Mege, Diane, Parc, Yann, Rullier, Eric, Cotte, Eddy, Meurette, Guillaume, Zerbib, Philippe, Trilling, Bertrand, Lelong, Bernard, Sabbagh, Charles, Lakkis, Zaher, Ouaissi, Mehdi, Lebreton, Gil, Rouanet, Philippe, Manceau, Gilles, Tuech, Jean-Jacques, Piessen, Guillaume, Bresler, Laurent, Beyer-Berjot, Laura, Denost, Quentin, Lefevre, Jeremie H., Panis, Yves, Gr, French Res Grp Rectal Canc Surg, Aix-Marseille Université - École de médecine (AMU SMPM MED), Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU)-Aix Marseille Université (AMU), Hôpital de la Timone [CHU - APHM] (TIMONE), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Haut-Lévêque [CHU Bordeaux], CHU Bordeaux [Bordeaux], Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Pierre-Bénite, Service de Chirurgie Digestive, Centre hospitalier universitaire de Nantes (CHU Nantes), CHU Lille, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Département de chirurgie digestive et de l'urgence, CHU Grenoble-Hôpital Michallon, CHU Pontchaillou [Rennes], CHU Amiens-Picardie, Simplification des soins chez les patients complexes - UR UPJV 7518 (SSPC), Université de Picardie Jules Verne (UPJV), Service de Chirurgie Digestive [CHRU Besançon], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Institut du Cancer de Montpellier (ICM), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Service de chirurgie digestive [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Service de Chirurgie Digestive Hépatobiliaire et Endocrine [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Hôpital Nord [CHU - APHM], Sorbonne Université (SU), and Sorbonne Université - Faculté de Médecine (SU FM)

Subjects
Adult, Male, medicine.medical_specialty, Postoperative ileus, Adolescent, [SDV]Life Sciences [q-bio], Young Adult, medicine, Humans, Surgical treatment, Laparoscopy, Rectal fistula, Aged, Retrospective Studies, Mean diameter, Laparotomy, Surgical approach, medicine.diagnostic_test, business.industry, Rectal Neoplasms, Incidence, Significant difference, Robotics, Middle Aged, Combined approach, Surgery, Treatment Outcome, Female, France, business
Abstract

International audience; Objective: To report the largest multicentric experience on surgical management of retrorectal tumors (RRT). Background: Literature data on RRT is limited. There is no consensus concerning the best surgical approach for the management of RRT. Methods: Patients operated for RRT in 18 academic French centers were retrospectively included (2000-2019). Results: A total of 270 patients were included. Surgery was performed through abdominal (n = 72, 27%), bottom (n = 190, 70%), or combined approach (n = 8, 3%). Abdominal approach was laparoscopic in 53/72 (74%) and bottom approach was Kraske modified procedures in 169/190 (89%) patients. In laparoscopic abdominal group, tumors were more frequently symptomatic (37/53, 70% vs 88/169, 52%, P = 0.02), larger [mean diameter = 60.5 +/- 24 (range, 13-107) vs 51 +/- 26 (20-105) mm, P = 0.02] and located above S3 vertebra (n = 3/42, 7% vs 0%, P = 0.001) than those from Kraske modified group. Laparoscopy was associated with a higher risk of postoperative ileus (n = 4/53, 7.5% vs 0%, P = 0.002) and rectal fistula (n = 3/53, 6% vs 0%, P=0.01) but less wound abscess (n = 1/53, 2% vs 24/169, 14%, P = 0.02) than Kraske modified procedures. RRT was malignant in 8%. After a mean follow up of 27 +/- 39 (1-221) months, local recurrence was noted in 8% of the patients. After surgery, chronic pain was observed in 17% of the patients without significant difference between the 2 groups (15/74, 20% vs 3/30, 10%; P = 0.3). Conclusions: Both laparoscopic and Kraske modified approaches can be used for surgical treatment of RRT (according to their location and their size), with similar long-term results.

Published
2021

33. Impact of preoperative enteral nutritional support on postoperative outcome in patients with Crohn’s disease complicated by malnutrition

Author

Abdalla, Solafah, Benoist, Stéphane, Maggiori, Léon, Zerbib, Philippe, Lefevre, Jérémie, Denost, Quentin, Germain, Adeline, Cotte, Eddy, Beyer‐Berjot, Laura, Corte, Hélène, Desfourneaux, Véronique, Rahili, Amine, Duffas, Jean‐Pierre, Pautrat, Karine, Denet, Christine, Bridoux, Valérie, Meurette, Guillaume, Faucheron, Jean‐Luc, Loriau, Jérôme, Guillon, Françoise, Vicaut, Eric, PANIS, Yves, Brouquet, Antoine, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Petites Molécules de neuroprotection, neurorégénération et remyélinisation, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hopital Saint-Louis [AP-HP] (AP-HP), CHU Lille, CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Bordeaux [Bordeaux], Centre Hospitalier Universitaire de Nancy (CHU Nancy), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Hôpital Nord [CHU - APHM], CHU Pontchaillou [Rennes], Centre Hospitalier Universitaire de Nice (CHU Nice), CHU Toulouse [Toulouse], Hôpital Lariboisière-Fernand-Widal [APHP], Institut Mutualiste de Montsouris (IMM), Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Service de chirurgie digestive [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Centre hospitalier universitaire de Nantes (CHU Nantes), Centre Hospitalier Universitaire [Grenoble] (CHU), Centre hospitalier Saint-Joseph [Paris], Hôpital Lapeyronie [Montpellier] (CHU), and Hôpital Beaujon

Subjects
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

34. Link between postoperative ileus and anastomotic leakage: A structural equation modelling approach

Author

Venara, Aurélien, primary, Hamel, Jean-Francois, additional, Beyer-Berjot, Laura, additional, Vignaud, Timothée, additional, Slim, Karem, additional, Abderrazak, M., additional, Abolo, H., additional, Abras, N., additional, Aissou, M., additional, Albertini, S., additional, Alfonsi, P., additional, Andre, A., additional, Arimont, J.M., additional, Arnalsteen, L., additional, Atger, J., additional, Attias, A., additional, Aumont, O., additional, Auvray, S., additional, Bachmann, R., additional, Barabino, G., additional, Barsotti, P., additional, Beauchesne, B., additional, Beaupel, N., additional, Beliard, A., additional, Bellouard, A., additional, Beloeil, H., additional, Ben Salem, F., additional, Benhamou, A., additional, Billard, V., additional, Binhas, M., additional, Binot, D., additional, Blache, J.L., additional, Blet, A., additional, Bongiovanni, J.P., additional, Bonnal, A., additional, Bonnet, M., additional, Boret, H., additional, Bossard, A.E., additional, Bothereau, H., additional, Bouarroudj, N., additional, Bouayed, A., additional, Bouchard, F., additional, Boumadani, M., additional, Bousquet, M., additional, Bouygues, V., additional, Bozio, G., additional, Brek, A., additional, Cadi, P., additional, Caillon, P., additional, Camerlo, A., additional, Capito, C., additional, Cardin, J.L., additional, Castiglioni, M., additional, Catinois, M.L., additional, Cattan, P., additional, Chambrier, C., additional, Chambrier, G., additional, Chapuis, O., additional, Chauvin, M., additional, Chokairi, S., additional, Chopin Laly, X., additional, Collange, V., additional, Cotte, E., additional, Cuellar, E., additional, D'errico, E., additional, Dahmani, S., additional, Danan, M., additional, De La Fontaine, C., additional, De Wailly, P., additional, Degauque, C., additional, Delacoste, F., additional, Denet, C., additional, Denost, Q., additional, Desaint, P., additional, Descamps, E., additional, Desfourneaux., V, additional, Desmet, J., additional, Desolneux, G., additional, Dileon, S., additional, Dolbeau, J.B., additional, Douard, R., additional, Dufour, F., additional, Dupont-Bierre, E., additional, Dupré, A., additional, Entremont, A., additional, Faucheron, J.L., additional, Fernoux, P., additional, Figuet, S., additional, Finianos, A., additional, Flamein, R., additional, Fletcher, D., additional, Fontes, J.P., additional, Fourn, E., additional, Gergeanu, S., additional, Germain, A., additional, Gignoux, B., additional, Goater, P., additional, Gres., P, additional, Grigoroiu, M., additional, Grillo, P., additional, Guignard, B., additional, Guinier, D., additional, Guiot, J.L., additional, Gutton, C., additional, Hadjadj, H., additional, Hail, K., additional, Hausermann, M.H., additional, Hennequin, S., additional, Homsy-Hubert, B., additional, Jambet, S., additional, Janecki, T., additional, Jannier-Guillou, V., additional, Jaspart, J., additional, Joly, F., additional, Joris, J., additional, Journe, F., additional, Kattou, F., additional, Kemoun, G., additional, Khalaf, M., additional, Klack, F., additional, Kothonidis, K., additional, Kurdi, O., additional, Laforest, A., additional, Lamblin, A., additional, Lammens, S., additional, Laporte, S., additional, Launay-Savary, M.V., additional, Le Maho, A.L., additional, Lemée, J.M., additional, Leonard, D., additional, Leporrier, J., additional, Lorin, J.L., additional, Magne, E., additional, Maisonnette, F., additional, Malherbe, V., additional, Manceau, G., additional, Mariani, P., additional, Massalou, D., additional, Massard, J.L., additional, Mauvais, F., additional, Mbuyamba, J., additional, Mbuyamba Katapile, J., additional, Mehila, T., additional, Meillat, H., additional, Mergui, C., additional, Michaud, P., additional, Milou, F., additional, Mirre, F., additional, Mor Martinez, C., additional, Mouchon, S., additional, Mouilhade, F., additional, Nguyen, Y.L., additional, Ostermann Bucher, S., additional, Page, M., additional, Parent, S., additional, Payen, A.L., additional, Pedicone, R., additional, Peluchon, P., additional, Pichot-Delahaye, V., additional, Piquard, A., additional, Pirlet, I., additional, Plard, L., additional, Poiblanc, M., additional, Poinas, G., additional, Poincenot, J., additional, Ponchel, C., additional, Pontallier, A., additional, Pop, R., additional, Potiron, E., additional, Proske, J.M., additional, Prunet, B., additional, Ras, E., additional, Raspado, O., additional, Raux, M., additional, Regimbeau, J.M., additional, Remue, C., additional, Renacco, F., additional, Riboud, R., additional, Richard-Payen, A.L., additional, Rio, D., additional, Sage, M., additional, Sage, P.Y., additional, Saint Denis, M., additional, Salaun, P., additional, Samyn, B., additional, Sbai Idrissi, M., additional, Schmitt, G., additional, Secq, E., additional, Seddiki, A., additional, Sens, N., additional, Sirieix, D., additional, Siriser, F., additional, Tarcea, M., additional, Tavernier, M., additional, Tete, B., additional, Theissen-Laval, O., additional, Thevenot, A., additional, Thievenaz, R., additional, Vacher, B., additional, Verhaeghe, R., additional, Verrier, J.F., additional, Vieuille, C., additional, Voilin, C., additional, Vuagnat, C., additional, and Zaepfel, S., additional

Published
2021
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38. Impact of hospital volume on outcomes after emergency management of obstructive colon cancer: a nationwide study of 1957 patients

Author

Aubert, Mathilde, Mege, Diane, Manceau, Gilles, Bridoux, Valerie, Lakkis, Zaher, Venara, Aurélien, Voron, Thibault, Abdalla, Solafah, BEYER-BERJOT, Laura, Sielezneff, Igor, Sabbagh, Charles, Karoui, Mehdi, Association française de Chirurgie, AFC, Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Assistance Publique - Hôpitaux de Marseille (APHM), Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de chirurgie digestive [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Service d'oncologie digestive et hépato-gastro-entérologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Chirurgie digestive [CHU Amiens], CHU Amiens-Picardie, Service d'hépato-gastro-entérologie [APHP Henri Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), AFC (French Surgical Association), and Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
medicine.medical_specialty, Hospitals, Low-Volume, Multivariate analysis, Colorectal cancer, Tumor resection, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, 030230 surgery, Stoma, 03 medical and health sciences, 0302 clinical medicine, Hospital volume, Internal medicine, medicine, Humans, Hospital Mortality, Retrospective Studies, business.industry, Volume, Anastomosis, Surgical, Gastroenterology, Cancer, Obstructive colon cancer, Length of Stay, Hepatology, medicine.disease, Colorectal surgery, 3. Good health, 030220 oncology & carcinogenesis, Colonic Neoplasms, Emergency surgery, National database, business, Hospitals, High-Volume
Abstract

International audience; PURPOSEVolume-outcome relationship is well established in elective colorectal surgery for cancer, but little is known for patients managed for obstructive colon cancer (OCC). We aimed to compare the management and outcomes according to the hospital volume in this particular setting. METHODS:Patients managed for OCC between 2005 and 2015 in centers of the French National Surgical Association were retrospectively analyzed. Hospital volume was dichotomized between low and high volume on the median number of patients included per center during the study period. RESULTSA total of 1957 patients with OCC were managed in 56 centers with a median number of 28 (1-123) patients per center: 298 (15%) were treated in low-volume hospitals (LVHs) and 1659 (85%) in high-volume hospitals (HVHs). Patients in LVH were significantly younger, and had fewer comorbidities and synchronous metastases. Proximal diverting stoma was the preferred surgical option in LVH (p

Published
2020

39. Additional file 1 of Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open-label, phase III study (NUTRILEAK study)

Author

Gronnier, Caroline, Chambrier, Cécile, Duhamel, Alain, Dervaux, Benoît, Collet, Denis, Vaudoyer, Delphine, Jean-Marc Régimbeau, Jougon, Jacques, Théréaux, Jérémie, Lebreton, Gil, Veziant, Julie, Valverde, Alain, Ortega-Deballon, Pablo, Pattou, François, Mathonnet, Muriel, Perinel, Julie, Beyer-Berjot, Laura, Fuks, David, Rouanet, Philippe, Lefevre, Jérémie H., Cattan, Pierre, Deguelte, Sophie, Meunier, Bernard, Jean-Jacques Tuech, Pessaux, Patrick, Carrere, Nicolas, Salame, Ephrem, Benaim, Eleonor, Dousset, Bertrand, Msika, Simon, Mariette, Christophe, and Piessen, Guillaume

Abstract

Additional file 1. SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents.

Published
2020
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40. Additional file 2 of Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open-label, phase III study (NUTRILEAK study)

Author

Gronnier, Caroline, Chambrier, Cécile, Duhamel, Alain, Dervaux, Benoît, Collet, Denis, Vaudoyer, Delphine, Jean-Marc Régimbeau, Jougon, Jacques, Théréaux, Jérémie, Lebreton, Gil, Veziant, Julie, Valverde, Alain, Ortega-Deballon, Pablo, Pattou, François, Mathonnet, Muriel, Perinel, Julie, Beyer-Berjot, Laura, Fuks, David, Rouanet, Philippe, Lefevre, Jérémie H., Cattan, Pierre, Deguelte, Sophie, Meunier, Bernard, Jean-Jacques Tuech, Pessaux, Patrick, Carrere, Nicolas, Salame, Ephrem, Benaim, Eleonor, Dousset, Bertrand, Msika, Simon, Mariette, Christophe, and Piessen, Guillaume

Subjects
humanities
Abstract

Additional file 2. Consent form.

Published
2020
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42. Advanced colonic cancer with clinically suspected bladder invasion: Outcomes and prognosis from a multicentric study of 117 patients from the FRENCH research group

Author

Vuillermet, Cindy, primary, Meillat, Hélène, additional, Manceau, Gilles, additional, Creavin, Ben, additional, Eveno, Clarisse, additional, Benoist, Stéphane, additional, Parc, Yann, additional, Lefevre, Jérémie H., additional, Arfa, Sara, additional, Dumont, Paul-Noël, additional, Boullenois, Hortense, additional, Fuks, David, additional, Ouaissi, Mehdi, additional, Benhaim, Leonor, additional, Selvy, Marie, additional, Tuech, Jean-Jacques, additional, Lakkis, Zaher, additional, Lupinacci, Renato, additional, Epin, Antoine, additional, Deguelte, Sophie, additional, Passot, Guillaume, additional, Trilling, Bertrand, additional, Jarlot-Gas, Cécile, additional, Mathonnet, Muriel, additional, Moszkowicz, David, additional, M’Harzi, Leila, additional, and Beyer Berjot, Laura, additional

Published
2020
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45. Is Adjuvant Chemotherapy Necessary for Obstructing Stage II Colon Cancer? Results From a Propensity Score Analysis of the French Surgical Association Database

Author

Sabbagh, Charles, primary, Manceau, Gilles, additional, Mege, Diane, additional, Abdalla, Solafah, additional, Voron, Thibault, additional, Bridoux, Valérie, additional, Lakkis, Zaher, additional, Venara, Aurélien, additional, Beyer-Berjot, Laura, additional, Diouf, Momar, additional, and Karoui, Mehdi, additional

Published
2020
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46. Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open label, phase III study (NUTRILEAK study)

Author

Gronnier, Caroline, primary, Chambrier, Cécile, additional, Duhamel, Alain, additional, Dervaux, Benoît, additional, Collet, Denis, additional, Vaudoyer, Delphine, additional, Régimbeau, Jean-Marc, additional, Jougon, Jacques, additional, Théréaux, Jérémie, additional, Lebreton, Gil, additional, Veziant, Julie, additional, Valverde, Alain, additional, Ortega-Deballon, Pablo, additional, Pattou, François, additional, Mathonnet, Muriel, additional, Perinel, Julie, additional, Beyer-Berjot, Laura, additional, Fuks, David, additional, Rouanet, Philippe, additional, Lefevre, Jérémie H, additional, Cattan, Pierre, additional, Deguelte, Sophie, additional, Meunier, Bernard, additional, Tuech, Jean-Jacques, additional, Pessaux, Patrick, additional, Carrere, Nicolas, additional, Salame, Ephrem, additional, Benaim, Eleonor, additional, Dousset, Bertrand, additional, Msika, Simon, additional, Mariette, Christophe, additional, and Piessen, Guillaume, additional

Published
2020
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48. Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open label, phase III study (NUTRILEAK study)

Author

Gronnier, Caroline, primary, Chambrier, Cécile, additional, Duhamel, Alain, additional, Dervaux, Benoît, additional, Collet, Denis, additional, Vaudoyer, Delphine, additional, Régimbeau, Jean-Marc, additional, Jougon, Jacques, additional, Théréaux, Jérémie, additional, Lebreton, Gil, additional, Veziant, Julie, additional, Valverde, Alain, additional, Ortega-Deballon, Pablo, additional, Pattou, François, additional, Mathonnet, Muriel, additional, Perinel, Julie, additional, Beyer-Berjot, Laura, additional, Fuks, David, additional, Rouanet, Philippe, additional, Lefevre, Jérémie H, additional, Cattan, Pierre, additional, Deguelte, Sophie, additional, Meunier, Bernard, additional, Tuech, Jean-Jacques, additional, Pessaux, Patrick, additional, Carrere, Nicolas, additional, Salame, Ephrem, additional, Benaim, Eleonor, additional, Dousset, Bertrand, additional, Msika, Simon, additional, Mariette, Christophe, additional, and Piessen, Guillaume, additional

Published
2019
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50. Laparoscopic rectal dissection preserves erectile function after ileal pouch–anal anastomosis: a two‐centre study.

Author

Picaud, Olivier, Beyer‐Berjot, Laura, Parc, Yann, Karsenty, Gilles, Creavin, Ben, Berdah, Stéphane, and Lefevre, Jérémie H.

Subjects
*LAPAROSCOPIC surgery, *FERTILITY, *APPENDECTOMY, *IMPOTENCE, *RESTORATIVE proctocolectomy, *INFERTILITY, *DISSECTION
Abstract

Aim: Few studies have been published on erectile function after ileal pouch–anal anastomosis (IPAA) and, unlike in women, male fertility after IPAA has never been assessed. The primary objective was to assess the impact of IPAA on erectile function. The secondary objective was to assess the impact of IPAA on male fertility. Methods: All of the male patients who underwent IPAA in two university care centres between 2003 and 2017, aged 70 years or less at the time of operation, were included. Forty‐eight per cent of the patients responded to the international index of erectile function, the Jorge–Wexner score and a fertility questionnaire. All demographic and perioperative data were prospectively collected. Fertility results were compared with those of a control group undergoing appendectomy, matched for age at the time of operation, desire for paternity and length of follow‐up. Results: One hundred and thirty‐nine patients were included, among which 46 (33%) presented with erectile dysfunction and 14 (10%) with severe erectile dysfunction. Age older than 50 years (OR 0.27, 95% CI 0.12–0.62, P = 0.002) and rectal dissection performed by open surgery (OR 4.16, 95% CI 1.62–10.65, P = 0.003) were independent risk factors for erectile dysfunction. There was no infertility after IPAA compared with controls: indeed, 23 (16%) IPAA patients presented with pregnancy in their couple versus 27 (22%) controls (P = 0.29), whereas 36 (26%) IPAA patients and 34 (28%) controls (P = 0.80) expressed paternity desire. Conclusion: A total laparoscopic approach, including rectal dissection, should be preferred to preserve erectile function. Male fertility is not impaired after IPAA. [ABSTRACT FROM AUTHOR]

Published
2021
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