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5. Long-term residential exposure to air pollution and risk of chronic respiratory diseases in Italy: The BIGEPI study

Author

Marchetti, Pierpaolo, Miotti, Jessica, Locatelli, Francesca, Antonicelli, Leonardo, Baldacci, Sandra, Battaglia, Salvatore, Bono, Roberto, Corsico, Angelo, Gariazzo, Claudio, Maio, Sara, Murgia, Nicola, Pirina, Pietro, Silibello, Camillo, Stafoggia, Massimo, Torroni, Lorena, Viegi, Giovanni, Verlato, Giuseppe, and Marcon, Alessandro

Published
2023
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6. Are nighttime respiratory symptoms assessed by asthma control test affected by comorbidities?

Author

Benfante, Alida, Tomasello, Alessandra, Caponetto, Chiara, Battaglia, Salvatore, and Scichilone, Nicola

Subjects
SLEEP quality, SLEEP interruptions, RHINITIS, ASTHMA, SLEEP disorders
Abstract

Objective: Nocturnal symptoms are common in the asthmatic population, reflecting an exaggerated airway narrowing overnight due to several factors; it is questioned to what extent the awakenings documented in the clinical assessment of asthma control are due to the disease itself or to comorbidities. To answer this question, we aimed to evaluate to what proportion rhinitis, gastroesophageal reflux and the likelihood of being affected by OSAS were related to poor asthma control, by means of ACT evaluation. Methods: Asthmatics attending the outpatient clinic were enrolled and administered the following questionnaires: ACT, Total 5 Symptom Score, GERD Impact Scale, Pittsburgh Sleep Quality Index and the Sleep Disorders Questionnaire. Results: One-hundred consecutive patients (M/F: 42/58, mean age 52 ± 15 years) were recruited. According to the ACT findings, 14 asthmatics resulted as fully controlled (FC, ACT equal to 25), 55 partially controlled (PC, 25 < ACT >19) and 31 as uncontrolled (UC, ACT <19). GERD was not associated with the ACT score neither did rhinitic symptomatology. On the other hand, the PSQI scores appeared to significantly increase with the lack of symptom control: FC, 2.0 (1–4); PC, 3.5 (2–5); UC, 6.6 (4–8) (p = 0.002). The SA-SDQ questionnaire results significantly increased with the loss of asthma control: FC, 11.0 (9–12); PC, 12.5 (10–14); UC, 15.1 (14–16) (p = 0.005). Conclusions: These results confirm and extend previous findings showing that there is a higher likelihood that underlying unknown sleep disturbances worsen asthma control, suggesting that a more comprehensive assessment is necessary to clarify the cause of nocturnal symptoms in asthma. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Diagnostic delay in bronchiectasis: an Italian perspective

Author

Chessari, Carlo, primary, Simonetta, Edoardo, additional, Amati, Francesco, additional, Nigro, Mattia, additional, Stainer, Anna, additional, Sotgiu, Giovanni, additional, Puci, Mariangela, additional, Gramegna, Andrea, additional, Blasi, Francesco, additional, Morlacchi, Letizia Corinna, additional, Buscemi, Agata Alba Maria Domenica, additional, Conio, Valentina, additional, Sanci, Vincenzo, additional, Corsico, Angelo G., additional, Faverio, Paola, additional, Michalak, Weronika, additional, Luppi, Fabrizio, additional, Crimi, Claudia, additional, Vancheri, Carlo, additional, Campisi, Raffaele, additional, Vulpi, Maria Rosaria, additional, Carpagnano, Giovanna Elisiana, additional, Cicchetti, Marianna, additional, Sekretna, Kseniia, additional, Scichilone, Nicola, additional, Battaglia, Salvatore, additional, and Aliberti, Stefano, additional

Published
2024
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9. Competing-risk analysis of coronavirus disease 2019 in-hospital mortality in a Northern Italian centre from SMAtteo COvid19 REgistry (SMACORE)

Author

Zuccaro, Valentina, Celsa, Ciro, Sambo, Margherita, Battaglia, Salvatore, Sacchi, Paolo, Biscarini, Simona, Valsecchi, Pietro, Pieri, Teresa Chiara, Gallazzi, Ilaria, Colaneri, Marta, Sachs, Michele, Roda, Silvia, Asperges, Erika, Lupi, Matteo, Di Filippo, Alessandro, Seminari, Elena, Di Matteo, Angela, Novati, Stefano, Maiocchi, Laura, Enea, Marco, Attanasio, Massimo, Cammà, Calogero, and Bruno, Raffaele

Published
2021
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13. An international perspective on hospitalized patients with viral community-acquired pneumonia

Author

Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic-Carevic, Vesna, Jakopovic, Marko, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Bødtger, Uffe, Meyer, Christian Niels, Vestergaard Jensen, Andreas, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Salvi, Sundeep, Limaye, Sneha, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d’Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F., Medenica, Milic, van de Garde, E.M.W., Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N.O., Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B., Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González Del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job F.M., Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Hancock, Carole, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Franco-Sadud, Ricardo A., Meier, Garnet, Gaga, Mina, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J., Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Angel, Luis F., Anzueto, Antonio, Scott Whitlow, K., Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Radovanovic, Dejan, Sotgiu, Giovanni, Jankovic, Mateja, Mahesh, Padukudru Anand, Marcos, Pedro Jorge, Abdalla, Mohamed I., Di Pasquale, Marta Francesca, Gramegna, Andrea, Terraneo, Silvia, Blasi, Francesco, Santus, Pierachille, Aliberti, Stefano, Reyes, Luis F., and Restrepo, Marcos I.

Published
2019
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20. Pre-operative incisional biopsy of oral squamous cell carcinoma: high podoplanin expression is related to perineural invasion and may be a useful predictor of disease progression

Author

Gabusi, Andrea, primary, Asioli, Sofia, additional, Fabbri, Viscardo P., additional, Fellegara, Giovanni, additional, Gibertoni, Dino, additional, Rossi, Roberto, additional, Battaglia, Salvatore, additional, Tarsitano, Achille, additional, Balbi, Tiziana, additional, Marchetti, Claudio, additional, Montebugnoli, Lucio, additional, Foschini, Maria Pia, additional, and Gissi, Davide B., additional

Published
2023
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21. Balancing Efficacy and Tolerability of First-Line Systemic Therapies for Advanced Hepatocellular Carcinoma: A Network Meta-Analysis

Author

Celsa, Ciro, primary, Cabibbo, Giuseppe, additional, Pinato, David James, additional, Di Maria, Gabriele, additional, Enea, Marco, additional, Vaccaro, Marco, additional, Battaglia, Salvatore, additional, Rizzo, Giacomo Emanuele Maria, additional, Giuffrida, Paolo, additional, Giacchetto, Carmelo Marco, additional, Rancatore, Gabriele, additional, Grassini, Maria Vittoria, additional, and Cammà, Calogero, additional

Published
2023
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24. Balancing Efficacy and Tolerability of First-Line Systemic Therapies for Advanced Hepatocellular Carcinoma: A Network Meta-Analysis.

Author

Celsa, Ciro, Cabibbo, Giuseppe, Pinato, David James, Di Maria, Gabriele, Enea, Marco, Vaccaro, Marco, Battaglia, Salvatore, Rizzo, Giacomo Emanuele Maria, Giuffrida, Paolo, Giacchetto, Carmelo Marco, Rancatore, Gabriele, Grassini, Maria Vittoria, and Cammà, Calogero

Subjects
IMMUNE checkpoint inhibitors, SURVIVAL rate, PROTEIN-tyrosine kinase inhibitors, OVERALL survival, ENDOTHELIAL growth factors, HEPATOCELLULAR carcinoma
Abstract

Background: Atezolizumab + bevacizumab represent the current standard of care for first-line treatment of advanced hepatocellular carcinoma (HCC). However, direct comparison with other combination treatments including immune checkpoint inhibitors (ICI) + tyrosine kinase inhibitors (TKIs) are lacking. Objectives: This network meta-analysis (NMA) aims to indirectly compare the efficacy and the safety of first-line systemic therapies for unresectable advanced HCC. Method: A literature search of MEDLINE, Embase, and SCOPUS databases was conducted up to October 31, 2022. Phase 3 randomized controlled trials (RCTs) testing TKIs, including sorafenib and lenvatinib, or ICIs reporting overall survival (OS) and progression-free survival (PFS) were included. Individual survival data were extracted from OS and PFS curves to calculate restricted mean survival time. A Bayesian NMA was performed to compare treatments in terms of efficacy (15- and 30-month OS, 6-month PFS) and safety, represented by grade ≥3 (severe) adverse events (SAEs). The incremental safety-effectiveness ratio as measure of net health benefit was calculated as the difference in SAE probability divided by survival difference between the 2 most effective treatments. Results: Nine RCTs enrolling 6,600 patients were included. Atezolizumab plus bevacizumab showed the highest probability (88%) of achieving the 30-month OS landmark. Lenvatinib showed a probability of 86% of achieving best PFS outcomes. ICI monotherapies ranked as most tolerable. Atezolizumab plus bevacizumab showed the best net health benefit for OS, compared to durvalumab plus tremelimumab. When evaluating the net health benefit for PFS, at a willingness-to-risk threshold of 10% of SAEs for life-month gained, atezolizumab plus bevacizumab was favoured in 78% of cases, while at threshold of 30% of SAEs for life-month gained, lenvatinib was favoured in 76% of cases. Conclusions: Atezolizumab plus bevacizumab is the best treatment in terms of net benefit and therefore it should be recommended as standard of care. Compared to atezolizumab plus bevacizumab, lenvatinib monotherapy had the best net benefit for PFS when physicians and patients are available to accept a higher risk of toxicity. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Balancing efficacy and tolerability of first-line systemic therapies for advanced hepatocellular carcinoma: a network metanalysis

Author

Celsa, Ciro, primary, Cabibbo, Giuseppe, additional, Di Maria, Gabriele, additional, Vaccaro, Marco, additional, Battaglia, Salvatore, additional, Maria Rizzo, Giacomo Emanuele, additional, Ciccia, Roberta, additional, Grova, Alessandro, additional, Salvato, Mauro, additional, Giuffrida, Paolo, additional, Giacchetto, Marco, additional, Rancatore, Gabriele, additional, Grassini, Maria Vittoria, additional, Antonucci, Michela, additional, Morana, Piera, additional, Enea, Marco, additional, and Camma, Calogero, additional

Published
2023
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27. Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study

Author

Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I, Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Di Tulio, Fernando, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Vincent, Jean Louis, Anseeuw, Kurt, Francois, Camille A, Van Braeckel, Eva, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic Carevic, Vesna, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Heitmann Bødtger, Uffe Christian, Meyer, Christian Niels, Vestergaard Jensen, Andreas, Baunbæk-knudsen, Gertrud, Trier Petersen, Pelle, Andersen, Stine, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W, Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D'Souza, George, Garg, Rajiv, Koul, Parvaiz A, Mahesh, P A, Jayaraj, B S, Narayan, Kiran Vishnu, Udnur, Hirennappa B, Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d'Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F, Medenica, Milic, van de Garde, E M W, Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N O, Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczynski, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B, Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanovic, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Marcos, Pedro J, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job FM, Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J, Feneley, Andrew, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S, Brito, Veronica, Dietz, Jessica, Dysart, Claire E, Kellie, Susan M, Franco-Sadud, Ricardo A, Meier, Garnet, Gaga, Mina, Holland, Thomas L, Bergin, Stephen P, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J, Noda, Julio, Hinojosa, Cecilia I, Levine, Stephanie M, Angel, Luis F, Anzueto, Antonio, Whitlow, K Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G, Shah, Ray D, Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Aliberti, Stefano, Reyes, Luis F, Faverio, Paola, Sotgiu, Giovanni, Dore, Simone, Rodriguez, Alejandro H, and Restrepo, Marcos I

Published
2016
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33. Impact of Actively Offering Influenza Vaccination to Frail People during Hospitalisation: A Pilot Study in Italy.

Author

Fallucca, Alessandra, Ferro, Patrizia, Mazzeo, Luca, Zagra, Luigi, Cocciola, Elena, Oliveri, Roberta, Tuttolomondo, Antonino, Benfante, Alida, Battaglia, Salvatore, Scichilone, Nicola, Veronese, Nicola, Affronti, Marco, Barbagallo, Mario, Casuccio, Alessandra, Vitale, Francesco, and Restivo, Vincenzo

Subjects
INFLUENZA vaccines, VACCINATION coverage, HOSPITAL care, PILOT projects
Abstract

Despite the worldwide recommendations for influenza immunisation, vaccination coverage for patients exposed to the highest risk of severe complications is still far from the optimal target. The need to take advantage of alternative methods to provide vaccination is essential. This study presents a hospital-based strategy which offers influenza vaccination to inpatients at discharge. This study was conducted during the 2022–2023 influenza season at the University Hospital of Palermo. A questionnaire was administered to identify the determinants for the acceptance of influenza vaccination in the frail population. Overall, 248 hospitalised patients were enrolled, of which 56.1% were female and 52.0% were over 65 years of age. The proportion of patients vaccinated against influenza during hospitalisation was 62.5%, an increase of 16% in influenza vaccination uptake among frail people in comparison with the previous influenza season (46.8% vaccinated during the 2021–22 influenza season). Factors significantly associated with vaccination acceptance were the following: to have received influenza vaccine advice from hospital healthcare workers (OR = 3.57, p = 0.001), to have been previously vaccinated for influenza (OR = 3.16 p = 0.005), and to have had a low level of education (OR = 3.56, p = 0.014). This study showed that offering influenza vaccination to hospitalised patients could be an effective strategy to increase vaccination coverage in the most vulnerable population, and these findings could be useful for planning and improving future influenza vaccination campaigns. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Reply

Author

Vizzutti, Francesco, primary, Celsa, Ciro, additional, Battaglia, Salvatore, additional, Miraglia, Roberto, additional, Enea, Marco, additional, Marra, Fabio, additional, Colecchia, Antonio, additional, Cammà, Calogero, additional, and Schepis, Filippo, additional

Published
2023
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37. The Association of Self-Reported Birthweight with Lung Function and Respiratory Diseases: Results from a Multi-Centre, Multi-Case Control Study in Italy

Author

Tocco Tussardi, Ilaria, primary, Tfaily, Ahmad, additional, Locatelli, Francesca, additional, Antonicelli, Leonardo, additional, Battaglia, Salvatore, additional, Bono, Roberto, additional, Corsico, Angelo G., additional, Murgia, Nicola, additional, Pirina, Pietro, additional, Ferrari, Marcello, additional, Tardivo, Stefano, additional, Jarvis, Deborah L., additional, and Verlato, Giuseppe, additional

Published
2022
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38. Echocardiographic Evaluation of the Cardiac Chambers in Asthmatic Patients: The BADA (Blood Pressure Levels, Clinical Features and Markers of Subclinical Cardiovascular Damage of Asthma Patients) Study-ECO

Author

Di Raimondo, Domenico, primary, Musiari, Gaia, additional, Rizzo, Giuliana, additional, Pirera, Edoardo, additional, Benfante, Alida, additional, Battaglia, Salvatore, additional, Colomba, Daniela, additional, Tuttolomondo, Antonino, additional, Scichilone, Nicola, additional, and Pinto, Antonio, additional

Published
2022
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39. Reply

Author

Vizzutti, Francesco, primary, Celsa, Ciro, additional, Battaglia, Salvatore, additional, Miraglia, Roberto, additional, Enea, Marco, additional, Marra, Fabio, additional, Caporali, Cristian, additional, Cammà, Calogero, additional, and Schepis, Filippo, additional

Published
2022
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40. RESIST-HCV Criteria to Monitor Progression of Low-Risk Esophageal Varices in Patients With Compensated Cirrhosis After HCV Eradication: The SIMPLE Study: SIMPLE: Scoring Index to Monitor Progression of Low-risk Esophageal varices

Author

Calvaruso, Vincenza, Celsa, Ciro, D'Ambrosio, Roberta, Simone, Fabio, Petta, Salvatore, Cacciola, Irene, Enea, Marco, Battaglia, Salvatore, Pandolfo, Alessandra, Licata, Massimo, Degasperi, Elisabetta, Cabibbo, Giuseppe, Di Marco, Lorenza, Pennisi, Grazia, Borghi, Marta, Di Martino, Vincenzo, Filomia, Roberto, Abdel-Hadi, Yasmin, Crapanzano, Luciano, Raimondo, Giovanni, Lampertico, Pietro, Craxì, Antonio, Cammà, Calogero, Di Marco, Vito, Calvaruso, Vincenza, Celsa, Ciro, D'Ambrosio, Roberta, Simone, Fabio, Petta, Salvatore, Cacciola, Irene, Enea, Marco, Battaglia, Salvatore, Pandolfo, Alessandra, Licata, Massimo, Degasperi, Elisabetta, Cabibbo, Giuseppe, Di Marco, Lorenza, Pennisi, Grazia, Borghi, Marta, Di Martino, Vincenzo, Filomia, Roberto, Abdel-Hadi, Yasmin, Crapanzano, Luciano, Raimondo, Giovanni, Lampertico, Pietro, Craxì, Antonio, Cammà, Calogero, and Di Marco, Vito

Subjects
Antiviral Agent, Male, Liver Cirrhosis, Hepatology, Platelet Count, Liver Cirrhosi, Gastroenterology, Hepacivirus, Hepatitis C, Chronic, Esophageal and Gastric Varices, Antiviral Agents, Elasticity Imaging Techniques, Esophageal and Gastric Varice, Humans, Female, Serum Albumin, Human, Aged
Abstract

Noninvasive criteria to predict the progression of low-risk esophageal varices (EV) in patients with compensated hepatitis C virus (HCV) cirrhosis after sustained virological response (SVR) by direct-acting antivirals (DAAs) are lacking. Our aim was to assess the diagnostic performance of Rete Sicilia Selezione Terapia-HCV (RESIST-HCV) criteria for EV progression compared with elastography-based criteria (Baveno VI, Expanded Baveno VI, and Baveno VII-HCV criteria).All consecutive patients observed at 3 referral centers with compensated HCV cirrhosis with or without F1 EV who achieved sustained virological response by DAAs were classified at last esophagogastroduodenoscopy (EGDS) as RESIST-HCV low risk (i.e., low probability of high-risk varices [HRV]) if platelets were120 × 10 9 /L and serum albumin3.6 g/dL or RESIST-HCV high risk (i.e., high probability of HRV) if platelets were120 × 10 9 /L or serum albumin3.6 g/dL. The primary outcome was the progression to HRV. The area under the receiver operating characteristic curve and decision curve analysis of noninvasive criteria were calculated.The cohort consisted of 353 patients in Child-Pugh class A (mean age 67.2 years, 53.8% males). During a mean follow-up of 44.2 months, 34 patients (9.6%, 95% CI 6.7%-13.5%) developed HRV. At the last EGDS, 178 patients (50.4%) were RESIST-low risk, and 175 (49.6%) were RESIST-high risk. RESIST-HCV criteria showed the highest area under the receiver operating characteristic curve (0.70, 95% confidence interval 0.65-0.75), correctly sparing the highest number of EGDS (54.3%), with the lowest false-positive rate (45.7%), compared with elastography-based criteria. Decision curve analysis showed that RESIST-HCV had higher clinical utility than elastography-based criteria.Biochemical-based RESIST-HCV criteria are useful to easily predict HRV development after HCV eradication by DAAs in patients with compensated cirrhosis and low-risk EV.

Published
2022

45. Mortality after transjugular intrahepatic portosystemic shunt in older adult patients with cirrhosis: A validated prediction model

Author

Vizzutti, Francesco, primary, Celsa, Ciro, additional, Calvaruso, Vincenza, additional, Enea, Marco, additional, Battaglia, Salvatore, additional, Turco, Laura, additional, Senzolo, Marco, additional, Nardelli, Silvia, additional, Miraglia, Roberto, additional, Roccarina, Davide, additional, Campani, Claudia, additional, Saltini, Dario, additional, Caporali, Cristian, additional, Indulti, Federica, additional, Gitto, Stefano, additional, Zanetto, Alberto, additional, Di Maria, Gabriele, additional, Bianchini, Marcello, additional, Pecchini, Maddalena, additional, Aspite, Silvia, additional, Di Bonaventura, Chiara, additional, Citone, Michele, additional, Guasconi, Tomas, additional, Di Benedetto, Fabrizio, additional, Arena, Umberto, additional, Fanelli, Fabrizio, additional, Maruzzelli, Luigi, additional, Riggio, Oliviero, additional, Burra, Patrizia, additional, Colecchia, Antonio, additional, Villa, Erica, additional, Marra, Fabio, additional, Cammà, Calogero, additional, and Schepis, Filippo, additional

Published
2022
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46. Efficacy and safety of Atezolizumab plus Bevacizumab-based sequential treatment for unresectable hepatocellular carcinoma: a simulation model

Author

Celsa, Ciro, primary, Cabibbo, Giuseppe, additional, Battaglia, Salvatore, additional, Giuffrida, Paolo, additional, Maria Rizzo, Giacomo Emanuele, additional, Grova, Mauro, additional, Giacchetto, Marco, additional, Rancatore, Gabriele, additional, Stornello, Caterina, additional, Grassini, Maria Vittoria, additional, Badalamenti, Giuseppe, additional, Enea, Marco, additional, Craxi, Antonio, additional, Di Marco, Vito, additional, and Camma, Calogero, additional

Published
2022
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