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2. Everolimus in heart transplantation: an update.

Author

Deuse, Tobias, Hirt, SW, Bara, C, Barten, MJ, Doesch, AO, Kaczmarek, I, Schulz, U, Stypmann, J, Haneya, A, and Lehmkuhl, HB

Abstract

The evidence base relating to the use of everolimus in heart transplantation has expanded considerably in recent years, providing clinically relevant information regarding its use in clinical practice. Unless there are special considerations to take into a

Published
2013

3. Intérêt d’une batterie spécialisée de tests épicutanés dans une cohorte de patients adressés pour hypersensibilité à leur implant orthopédique. Une étude multicentrique du DAG

Author

Gautier, C., Giordano-Labadie, F., Marcant, P., Castelain, F., Raison-Peyron, N., Milpied, B., Kurihara, F., Bara, C., Ferrier-Le Bouedec, M.C., Pasteur, J., Tetart, F., Assier, H., Morice, C., Bernier, C., Delaunay, J., Valois, A., Boulard, C., Crepy, M.N., Leleu, C., Chasset, F., Hardy, A., and Barbaud, A.

Published
2024
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5. Rehabilitation Modulates High-Order Interactions among Large-Scale Brain Networks in Subacute Stroke

Author

Pirovano, I, Antonacci, Y, Mastropietro, A, Bara, C, Sparacino, L, Guanziroli, E, Molteni, F, Tettamanti, M, Faes, L, Rizzo, G, Pirovano, I, Antonacci, Y, Mastropietro, A, Bara, C, Sparacino, L, Guanziroli, E, Molteni, F, Tettamanti, M, Faes, L, and Rizzo, G

Abstract

The recovery of motor functions after stroke is fostered by the functional integration of large-scale brain networks, including the motor network (MN) and high-order cognitive controls networks, such as the default mode (DMN) and executive control (ECN) networks. In this paper, electroencephalography signals are used to investigate interactions among these three resting state networks (RSNs) in subacute stroke patients after motor rehabilitation. A novel metric, the O-information rate (OIR), is used to quantify the balance between redundancy and synergy in the complex high-order interactions among RSNs, as well as its causal decomposition to identify the direction of information flow. The paper also employs conditional spectral Granger causality to assess pairwise directed functional connectivity between RSNs. After rehabilitation, a synergy increase among these RSNs is found, especially driven by MN. From the pairwise description, a reduced directed functional connectivity towards MN is enhanced after treatment. Besides, inter-network connectivity changes are associated with motor recovery, for which the mediation role of ECN seems to play a relevant role, both from pairwise and high-order interactions perspective.

Published
2023

6. Investigating the Heartbeat-evoked cortical responses through parametric Time-Varying Information Measures

Author

Antonacci, Y, Bara, C, Zaccaro, A, Ferri, F, Augugliaro, L, Faes, L, Antonacci, Y, Bara, C, Zaccaro, A, Ferri, F, Augugliaro, L, and Faes, L

Subjects
information storage, Recursive least square, information theory
Abstract

Recent studies showed that the information coming from the heart is constantly processed by the brain. One index to study this process is the heartbeat-evoked potential (HEP), represented by an event-related potential component related to the cortical processing of the heartbeat. In this study we propose an approach to investigate the heartbeat-evoked EEG responses, based on quantifying the changes induced by the heartbeat on the predictability of the brain dynamics. The regularity of EEG signals is assessed through the Information Storage (IS) computed with a time-varying approach able to derive the temporal profile of the measure for each time point. Results show a modulation in the regularity of EEG signals induced by the heartbeat that can be revealed with the proposed approach in a group of healthy subjects during a resting state.

Published
2022
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7. Vascular Remodeling on Intermediate and Long-Term left Ventricular Assist Device (LVAD) Support Under Nonpulsatile versus Pulsatile Blood Flow.

Author

Niehaus, A., Franz, B., Knigina, L., Schmitto, J.D., Haverich, A., Ruhparwar, A., and Bara, C.

Subjects
HEART assist devices, PULSATILE flow, VASCULAR remodeling, BLOOD flow, CARDIOVASCULAR system
Abstract

This article examines the effects of nonpulsatile blood flow on the vascular system in patients with left ventricular assist devices (LVADs). The study included 59 patients with continuous-flow LVADs, with 30 patients having nonpulsatile flow and 29 patients having pulsatile flow. The results showed that patients with nonpulsatile flow had a trend towards a larger intima area compared to those with pulsatile flow. Additionally, the relative intima thickness in relation to the total vessel wall increased over time in patients with nonpulsatile flow. These findings suggest that long-term nonpulsatile flow during LVAD support may lead to the development of atherosclerosis and increased fragility of arterial vessels. Further research is needed to fully understand the long-term morphological changes. [Extracted from the article]

Published
2024
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8. Impact du traitement par dupilumab sur les résultats des patch tests

Author

Boquel, S., primary, Soria, A., additional, Badaoui, A., additional, Marcant, P., additional, Bara, C., additional, Peyron, N. Raison, additional, Crepy, M.N., additional, Giordano-Labadie, F., additional, Amsler, E., additional, Milpied, B., additional, Delaunay, J., additional, Darrigade, A.S., additional, Pralong, P., additional, Boulard, C., additional, Bouedec, M.C. Ferrier Le, additional, Tauber, M., additional, Pasteur, J., additional, Valois, A., additional, and Bernier, C., additional

Published
2023
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10. Impact du traitement par dupilumab sur les résultats des patch-tests

Author

Bocquel, S., primary, Soria, A., additional, Badaoui, A., additional, Marcant, P., additional, Bara, C., additional, Raison Peyron, N., additional, Crépy, M.N., additional, Giordano-Labadie, F., additional, Amsler, E., additional, Milpied, B., additional, Delaunay, J., additional, Darrigade, A.S., additional, Pralong, P., additional, Boulard, C., additional, Ferrier Le Bouedec, M.C., additional, Tauber, M., additional, Pasteur, J., additional, Valois, A., additional, and Bernier, C., additional

Published
2022
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12. Le sérum physiologique n’augmente pas la sensibilité des patch-tests dans les toxidermies

Author

Assier, H., Bara, C., Milpied, B., Tauber, M., Bensaid, B., Bernier, C., Dupire, G., Castelain, F., Beaulieu, V., Soria, A., Bel Hareth, K., and Oro, S.

Abstract

Les tests allergologiques, en particulier les patch-tests (PT), sont une aide importante pour l’enquête étiologique des toxidermies mais leur sensibilité est variable selon les molécules testées. Le véhicule utilisé pour réaliser les PT peut influencer leur sensibilité. Une étude récente suggère que l’utilisation du sérum physiologique (SP) comme véhicule pourrait augmenter la sensibilité des PT. Nous rapportons notre expérience des PT dans le SP.

Published
2024
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14. Rehabilitation Modulates High-Order Interactions Among Large-Scale Brain Networks in Subacute Stroke.

Author

Pirovano, I., Antonacci, Y., Mastropietro, A., Bara, C., Sparacino, L., Guanziroli, E., Molteni, F., Tettamanti, M., Faes, L., and Rizzo, G.

Subjects
LARGE-scale brain networks, FUNCTIONAL magnetic resonance imaging, EXECUTIVE function, TIME series analysis, STROKE
Abstract

The recovery of motor functions after stroke is fostered by the functional integration of large-scale brain networks, including the motor network (MN) and high-order cognitive controls networks, such as the default mode (DMN) and executive control (ECN) networks. In this paper, electroencephalography signals are used to investigate interactions among these three resting state networks (RSNs) in subacute stroke patients after motor rehabilitation. A novel metric, the O-information rate (OIR), is used to quantify the balance between redundancy and synergy in the complex high-order interactions among RSNs, as well as its causal decomposition to identify the direction of information flow. The paper also employs conditional spectral Granger causality to assess pairwise directed functional connectivity between RSNs. After rehabilitation, a synergy increase among these RSNs is found, especially driven by MN. From the pairwise description, a reduced directed functional connectivity towards MN is enhanced after treatment. Besides, inter-network connectivity changes are associated with motor recovery, for which the mediation role of ECN seems to play a relevant role, both from pairwise and high-order interactions perspective. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Éruptions eczématiformes chroniques du sujet âgé : quelle imputabilité médicamenteuse ?

Author

Bouteiller, J., primary, Grosjean, J., additional, Delaunay, J., additional, Jachiet, M., additional, Bara, C., additional, Nosbaum, A., additional, Bouschon, P., additional, Milpied, B., additional, Oro, S., additional, Assier, H., additional, Guelimi, R., additional, Valois, A., additional, Viguier, M., additional, Dezoteux, F., additional, Staumont-Sallé, D., additional, Boulard, C., additional, Brenaut, E., additional, Morice, C., additional, Raison Peyron, N., additional, Joly, P., additional, and Tetart, F., additional

Published
2022
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22. Lack of referral for genetic counseling and testing in BRCA1/2 and Lynch syndromes: a nationwide study based on 240,134 consultations and 134,652 genetic tests

Author

Pujol, P., Lyonnet, D. Stoppa, Frebourg, T., Blin, J., Picot, M. C., Lasset, C., Dugast, C., Berthet, P., de Paillerets, B. Bressac, Sobol, H., Grandjouan, S., Soubrier, F., Buecher, B., Guimbaud, R., Lidereau, R., Jonveaux, P., Houdayer, C., Giraud, S., Olschwang, S., Nogue, E., Galibert, V., Bara, C., Nowak, F., Khayat, D., and Nogues, C.

Published
2013
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24. Folliculotropic T-cell infiltrates associated with B-cell chronic lymphocytic leukaemia or MALT lymphoma may reveal either true mycosis fungoides or pseudolymphomatous reaction: seven cases and review of the literature

Author

Ingen-Housz-Oro, S., Franck, N., Beneton, N., Fauconneau, A., Do-Pham, G., Carlotti, A., Petit, T., Liolios, I., Bara, C., Carpentier, H., Storelli, D., Prophette, B., Garderet, L., Haioun, C., Petit, E., Delfau-Larue, M.-H., Vergier, B., Chosidow, O., Beylot-Barry, M., and Ortonne, N.

Published
2015
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27. Management of urticaria by French specialists compared to international guideline recommendations

Author

Berard, F., Viguier, M., Lefevre, S., Vigan, M., Barzegar, C., Boussaid, R., Hacard, F., Gabison, G., Staumont, D., Marmion, N., Pouplard, C., Delaunay, J., Badaoui, A., Nosbaum, A., Pralong, P., Castelain, F., Bouillet, L., Sarre, M.E., Vermeulen, C., Tetart, F., Bachtarzi, Z., Doutre, M.S., Martinache, C., Bara, C., Augey, F., Boccon Gibod, I., Nicolas, J.F., Maatouk, I., Mathelier Fusade, P., Soutou, B., Goujon Henry, C., Hoarau, C., Crépy, M.N., Bernier, C., Cambazard, F., Guinepain, M.T., Amsler, Emmanuelle, Du Thanh, Aurelie, and Soria, Angèle

Published
2020
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29. Efficacité et tolérance en vie réelle du baricitinib dans le traitement de la pelade de l’adulte : étude rétrospective multicentrique

Author

Mourtada, A., Douarec, C., Wargny, M., Hebert, V., Reguiai, Z., Joly, P., Seneschal, J., Toussaint, C., Aubert, H., Le Moigne, M., Bernier, C., Passeron, T., Jacobzone Leveque, C., Soenen, A., Reygagne, P., Le Naour, S., Berthin, C., Bara, C., Fouchard, M., Janela-Lapert, R., Masson Regnault, M., Duval-Modeste, A.B., Jachiet, M., Fenot, M., Adamski, H., Marniquet, M.E., Lévy, M., and Barbarot, S.

Abstract

La pelade est une maladie auto-immune chronique associée à un retentissement psychologique majeur. Son incidence cumulée au cours de la vie est estimée à 2,1 %. Le baricitinib est un inhibiteur de JAK 1/2 ayant obtenu l’AMM française en 2023, puis en 2024 le remboursement dans le traitement de la pelade sévère de l’adulte. Peu de données en vie réelle sont disponibles concernant l’efficacité et la sécurité d’emploi du baricitinib dans cette indication.

Published
2024
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30. Réévaluation de l’imputabilité médicamenteuse dans la survenue d’éruptions eczématiformes chroniques du sujet âgé par comparaison aux données du SNDS dans la population générale

Author

Tétart, F., Bouteiller, J., Thill, C., Guérin, O., Lacroix, E., Delaunay, J., Jachiet, M., Bara, C., Nosbaum, A., Bouschon, P., Milpied, B., Oro, S., Assier, H., Guelimi, R., Valois, A., Viguier, M., Dezoteux, F., Staumont-Sallé, D., Boulard, C., Brenaut, E., Morice, C., Droitcourt, C., Ferrier Le Bouedec, M.C., Pasteur, J., Raison-Peyron, N., Grosjean, J., and Joly, P.

Abstract

Les éruptions eczématiformes chroniques du sujet âgé (EECSA) sont un motif fréquent de consultation. Les inhibiteurs calciques ont été mis en cause dans deux études, mais d’autres médicaments comme les diurétiques thiazidiques, les antiagrégants et les statines ont également été suspectés. L’objectif de l’étude a été de réévaluer l’imputabilité de certaines classes de médicaments dans la survenue d’une EECSA sans cause.

Published
2024
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35. Chronic Hepatitis E in Heart Transplant Recipients

Author

Pischke, S., Stiefel, P., Franz, B., Bremer, B., Suneetha, P. V., Heim, A., Ganzenmueller, T., Schlue, J., Horn-Wichmann, R., Raupach, R., Darnedde, M., Scheibner, Y., Taubert, R., Haverich, A., Manns, M. P., Wedemeyer, H., and Bara, C. L.

Published
2012
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40. Treatment of ANTI-HLA Donor-Specific Antibodies and Antibody-Mediated Rejection in Heart Transplantation: A Single-Center 3-Year Experience

Author

Salman, J., additional, Kaufeld, T., additional, Aburahma, K., additional, Bara, C., additional, Niehaus, A., additional, Poyanmehr, R., additional, Franz, M., additional, Falk, C., additional, Sommer, W., additional, Warnecke, G., additional, Haverich, A., additional, Avsar, M., additional, and Ius, F., additional

Published
2021
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46. Pemphigoïdes bulleuses associées aux anti-PD-1/PDL-1 : étude nationale de 85 cas

Author

Juzot, C., primary, Sibaud, V., additional, Amatore, F., additional, Mansard, S., additional, Seta, V., additional, Jeudy, G., additional, Pham-Ledard, A., additional, Benzaquen, M., additional, Dinulescu, M., additional, Le Corre, Y., additional, Lesage, C., additional, Viguier, M., additional, Baroudjian, B., additional, Clerc, C.-J., additional, Funck-Brentano, E., additional, Giacchero, D., additional, Mortier, L., additional, Peuvrel, L., additional, Machet, L., additional, Duvert-Lehembre, S., additional, Viarnaud, A., additional, Joachim, C., additional, Bara, C., additional, Baubion, E., additional, Bergeret, B., additional, Brunet-Possenti, F., additional, Debarbieux, S., additional, Hébert, V., additional, Konstantinou, M.-P., additional, Marzouki-Zerouali, A., additional, Moreau-Huguen, J., additional, Phan, C., additional, Templier, I., additional, Celerier, P., additional, Aubin, F., additional, Modiano, P., additional, Poinas, A., additional, Vibet, M.-A., additional, Dréno, B., additional, and Quéreux, G., additional

Published
2020
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47. Management of urticaria by French specialists compared to international guideline recommendations

Author

Amsler, Emmanuelle, primary, Du Thanh, Aurelie, additional, Soria, Angèle, additional, Berard, F., additional, Viguier, M., additional, Lefevre, S., additional, Vigan, M., additional, Barzegar, C., additional, Boussaid, R., additional, Hacard, F., additional, Gabison, G., additional, Staumont, D., additional, Marmion, N., additional, Pouplard, C., additional, Delaunay, J., additional, Badaoui, A., additional, Nosbaum, A., additional, Pralong, P., additional, Castelain, F., additional, Bouillet, L., additional, Sarre, M.E., additional, Vermeulen, C., additional, Tetart, F., additional, Bachtarzi, Z., additional, Doutre, M.S., additional, Martinache, C., additional, Bara, C., additional, Augey, F., additional, Boccon Gibod, I., additional, Nicolas, J.F., additional, Maatouk, I., additional, Mathelier Fusade, P., additional, Soutou, B., additional, Goujon Henry, C., additional, Hoarau, C., additional, Crépy, M.N., additional, Bernier, C., additional, Cambazard, F., additional, and Guinepain, M.T., additional

Published
2020
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49. Ex Vivo Organ Perfusion for Heart Procurement in High-Risk Transplantations: A Multicenter Study

Author

Rojas, S.V., primary, Ius, F., additional, Schibilsky, D., additional, Kaufeld, T., additional, Benk, C., additional, Sommer, W., additional, Goecke, T., additional, Avsar, M., additional, Poyanmehr, R., additional, Rümke, S., additional, Mogaldea, A., additional, Bobylev, D., additional, Salman, J., additional, Siemeni, T., additional, Bara, C., additional, Beyersdorf, F., additional, Haverich, A., additional, Siepe, M., additional, and Warnecke, G., additional

Published
2020
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