1. A pilot study of dried blood spot testing for HIV antibody in neonates
- Author
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J V, Dadswell, B, Dowding, M, Fletcher, G J, Pinney, J, Sellwood, and D L, Williams
- Subjects
Neonatal Screening ,England ,HIV Seroprevalence ,Immunoglobulin G ,Infant, Newborn ,AIDS Serodiagnosis ,Humans ,Women's Health ,Female ,Pilot Projects ,HIV Antibodies - Abstract
An unlinked anonymous HIV antibody study of neonates, using surplus dried blood spots on Guthrie cards, was introduced as a means of estimating the prevalence of HIV infection in childbearing women. From March 1990 to February 1992, blood spots from 14,520 infants were tested for anti-HIV, using an HIV IgG antibody capture particle-adherence test; only one sample gave a confirmed positive reaction. This type of study involves no interference in routine care and can be operated without difficulty in a district general hospital setting where neonatal metabolic screening is performed.
- Published
- 1992