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6 results on '"B Kaan, Inan"'

1. Stentless Bioprosthesis Provided Excellent Hemodynamic Performance in a Military Scuba Diver With Infective Endocarditis

Author

Mert Dumantepe, A. Turan Yilmaz, Gurkan Komurcu, B. Kaan Inan, and A. Umit Gullu

Subjects
Adult, Male, Aortic valve, medicine.medical_specialty, Turkey, Diving, medicine.medical_treatment, Perforation (oil well), Hemodynamics, Valve replacement, Humans, Medicine, Endocarditis, Bioprosthesis, Debridement, biology, business.industry, Public Health, Environmental and Occupational Health, General Medicine, Viridans Streptococci, biology.organism_classification, medicine.disease, Surgery, Military Personnel, medicine.anatomical_structure, Viridans streptococci, Aortic Valve, Heart Valve Prosthesis, Infective endocarditis, Stents, business
Abstract

Infective endocarditis is a diagnostic and therapeutic challenge that ultimately requires surgical intervention in 20% of all cases. Surgical treatment of active infective endocarditis requires not only hemodynamic repair, but also special emphasis on the eradiation of the infectious focus to prevent recurrence. This goal can be achieved by the combination of aggressive debridement of infective tissue and appropriate and adequate antibiotic treatment. We report a case of Streptococcus viridans induced aortic valve perforation related to aortic valve and root endocarditis, which was successfully treated with aortic root replacement using stentless bioprosthesis. This bioprosthesis thus seems to be a valuable option for active endocarditis, provides excellent hemodynamics with low gradients. Acceptable operative risk can be achieved by full root stentless valve replacement in physically active patients such as divers.

Published
2009
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2. Left main coronary artery and supravalvular aortic stenosis in adult: treatment with ostial patchplasty and modified Brom procedure

Author

Ahmet Turan Yilmaz, A. Umit Gullu, Alper Ucak, Murat Ugur, Veysel Temizkan, and B. Kaan Inan

Subjects
Pulmonary and Respiratory Medicine, Aortic valve, Male, medicine.medical_specialty, Cardiac Catheterization, medicine.medical_treatment, Young Adult, Blood vessel prosthesis, Internal medicine, medicine, Ventricular outflow tract, Humans, Cardiac catheterization, Heart Valve Prosthesis Implantation, business.industry, Polyethylene Terephthalates, Coronary Stenosis, Surgical Mesh, medicine.disease, Aortic Stenosis, Subvalvular, Blood Vessel Prosthesis, Stenosis, medicine.anatomical_structure, Surgical mesh, cardiovascular system, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business, Supravalvular aortic stenosis, Echocardiography, Transesophageal, Artery, Follow-Up Studies
Abstract

Left main coronary artery (LMCA) stenosis accompanying to supravalvular aortic stenosis is a very uncommon, serious congenital abnormality. Aortic valve leaflet fusions and intimal thickening of the aortic valve leaflets and coronary artery are the underlying pathologies for the LMCA stenosis. We operated on a 21-year-old male patient for supravalvar aortic stenosis with LMCA ostial stenosis. We enlarged the LMCA with a pericardial patch (ostial plasty) and reconstructed the aortic root with a modified Brom procedure. Postoperative course was uneventful; echocardiographic evaluation revealed a normal functioning aortic valve with a normal left ventricular function. Gradient at left ventricular outflow tract was decreased a great deal. Although supravalvular aortic stenosis with LMCA stenosis is a very rare congenital abnormality, this clinical entity can be successfully corrected with detailed and selected surgical procedures.

Published
2009

5. Repair of ascending aortic aneurysm in a patient with lipomatous hypertrophy of the interatrial septum.

Author

Uçak, Alper, B. Kaan İnan, Us, H. Melih, and Yılmaz, Ahmet Turan

Subjects
*HYPERTROPHY, *AORTIC aneurysms, *AORTA surgery, *ECHOCARDIOGRAPHY, *PATHOLOGY
Abstract

The article discusses surgery performed to treat the first case of ascending aortic aneurysm (AAA) combined with lipomatous hypertrophy. The patient was a 67-year-old woman with increasing shortness of breath on exertion. An electrocardiographic examination revealed an ascending aortic aneurysm with a 5.5cm mass, which suggested an atrial tumor. An atriotomy revealed a 2.5cm tumor. A 28mm Dacron graft was used to perform a supracoronary ascending aortic replacement.

Published
2008

6. Linezolid alone and in combination with rifampicin prevents experimental vascular graft infection due to methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.

Author

Sacar M, Sacar S, Kaleli I, Onem G, Turgut H, Goksin I, Ozcan V, Kaan Inan B, Duver H, and Baltalarli A

Subjects
Animals, Anti-Bacterial Agents pharmacology, Drug Synergism, Linezolid, Male, Rats, Rats, Wistar, Staphylococcus aureus drug effects, Staphylococcus aureus physiology, Staphylococcus epidermidis drug effects, Staphylococcus epidermidis physiology, Teicoplanin pharmacology, Acetamides pharmacology, Anti-Infective Agents pharmacology, Blood Vessel Prosthesis, Methicillin Resistance, Oxazolidinones pharmacology, Prosthesis-Related Infections prevention & control, Rifampin pharmacology, Staphylococcal Infections prevention & control
Abstract

Background: In this report we describe the in vivo antibacterial activity of linezolid in an experimental graft infection model in rats and compare it with teicoplanin. The objective of this study was also to determine the effects of the interaction of linezolid when it was combined with rifampicin and test this effect against strains of methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis., Materials and Methods: Graft infections were established in the subcutaneous tissue of 130 Wistar rats by implantation of Dacron grafts followed by a topical inoculation with 2 x 10(7) CFU of clinical isolates of MRSA and MRSE. The study included a control group and six groups for each of the staphylococcal strains: an inoculated group that did not receive any antibiotic prophylaxis, two inoculated groups that received intraperitoneal prophylaxis with teicoplanin or linezolid alone, an inoculated group that received rifampicin-soaked grafts, and two inoculated groups that received a combination prophylaxis consisting of intraperitoneal teicoplanin or linezolid and rifampicin-soaked grafts., Results: There was a reduction in the quantitative bacterial graft cultures in all prophylaxis groups when compared with inoculated control groups. There was not a statistically significant difference between linezolid and teicoplanin prophylaxis groups. The best results were obtained by a combination of rifampicin-soaked grafts with linezolid or teicoplanin., Conclusions: We found no evidence to suggest that linezolid differs from teicoplanin regarding effectiveness in the prevention of prosthetic vascular graft infection. Linezolid plus rifampicin and teicoplanin plus rifampicin are demonstrated to be valuable prophylactic regimens.

Published
2007
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