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2. Stereotactic radiosurgery and radiotherapy for resected brain metastases: current pattern of care in the Radiosurgery and Stereotactic Radiotherapy Working Group of the German Association for Radiation Oncology (DEGRO)

Author

Rogers, S., Baumert, B., Blanck, O., Böhmer, D., Boström, J., Engenhart-Cabillic, R., Ermis, E., Exner, S., Guckenberger, M., Habermehl, D., Hemmatazad, H., Henke, G., Lohaus, F., Lux, S., Mai, S., Minasch, D., Rezazadeh, A., Steffal, C., Temming, S., Wittig, A., Zweifel, C., Riesterer, O., and Combs, S. E.

Published
2022
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3. Correction to: Stereotactic radiosurgery and radiotherapy for resected brain metastases: current pattern of care in the Radiosurgery and Stereotactic Radiotherapy Working Group of the German Association for Radiation Oncology (DEGRO)

Author

Rogers, S., Baumert, B., Blanck, O., Böhmer, D., Boström, J., Engenhart-Cabillic, R., Ermis, E., Exner, S., Guckenberger, M., Habermehl, D., Hemmatazad, H., Henke, G., Lohaus, F., Lux, S., Mai, S., Minasch, D., Rezazadeh, A., Steffal, C., Temming, S., Wittig, A., Zweifel, C., Riesterer, O., and Combs, S. E.

Published
2023
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7. ComBat-Harmonisierung von FDG-PET/CT-basierten Radiomics zur Vorhersage des progressionsfreien Überlebens beim nicht-kleinzelligen Lungenkarzinom

Author

Rogasch, J., additional, Lugani, E., additional, Baumgärtner, G. L., additional, Frost, N., additional, Neudecker, J., additional, Rückert, J., additional, Schmidt, B., additional, Schneider, P., additional, Böhmer, D., additional, Ochsenreither, S., additional, Amthauer, H., additional, Penzkofer, T., additional, and Furth, C., additional

Published
2023
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9. Influence of different spectra of NOTCH3 variants on the clinical phenotype of CADASIL – experience from Slovakia

Author

Juhosová, M., primary, Chandoga, J., additional, Cisárik, F., additional, Dallemule, S., additional, Ďurina, P., additional, Jarásková, D., additional, Jungová, P., additional, Kantarská, D., additional, Kvasnicová, M., additional, Mistrík, M., additional, Pastoráková, A., additional, Petrovič, R., additional, Valachová, A., additional, Zelinková, H., additional, Barošová, J., additional, Böhmer, D., additional, and Štofko, J., additional

Published
2022
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10. Correction to: Stereotactic radiosurgery and radiotherapy for resected brain metastases: current pattern of care in the Radiosurgery and Stereotactic Radiotherapy Working Group of the German Association for Radiation Oncology (DEGRO)

Author

Rogers, S., primary, Baumert, B., additional, Blanck, O., additional, Böhmer, D., additional, Boström, J., additional, Engenhart-Cabillic, R., additional, Ermis, E., additional, Exner, S., additional, Guckenberger, M., additional, Habermehl, D., additional, Hemmatazad, H., additional, Henke, G., additional, Lohaus, F., additional, Lux, S., additional, Mai, S., additional, Minasch, D., additional, Rezazadeh, A., additional, Steffal, C., additional, Temming, S., additional, Wittig, A., additional, Zweifel, C., additional, Riesterer, O., additional, and Combs, S. E., additional

Published
2022
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11. Machine Learning for the Prediction of Distant Metastases Following Postprostatectomy Salvage Radiation Therapy

Author

Sabbagh, A., primary, Tilki, D., additional, Feng, J., additional, Hong, J.C., additional, Chen, M.H., additional, Wu, J., additional, Huland, H., additional, Graefen, M., additional, Wiegel, T., additional, Böhmer, D., additional, Washington, S., additional, Cowan, J., additional, Cooperberg, M.R., additional, Feng, F.Y., additional, Carroll, P., additional, Trock, B., additional, Partin, A.W., additional, DAmico, A.V., additional, and Mohamad, O., additional

Published
2022
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12. Machine Learning for the Prediction of Lymph Node Metastasis in Patients with Prostate Cancer

Author

Sabbagh, A., primary, III, S. Washington, additional, Tilki, D., additional, Hong, J.C., additional, Feng, J., additional, Chen, M.H., additional, Wu, J., additional, Huland, H., additional, Graefen, M., additional, Wiegel, T., additional, Böhmer, D., additional, Cowan, J., additional, Cooperberg, M.R., additional, Feng, F.Y., additional, Trock, B., additional, Partin, A.W., additional, DAmico, A.V., additional, Carroll, P., additional, and Mohamad, O., additional

Published
2022
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18. A randomized phase III adjuvant study in high-risk cervical cancer: simultaneous radiochemotherapy with cisplatin (S-RC) versus systemic paclitaxel and carboplatin followed by percutaneous radiation (PC-R): a NOGGO-AGO Intergroup Study

Author

Sehouli, J., Runnebaum, I.B., Fotopoulou, C., Blohmer, U., Belau, A., Leber, H., Hanker, L.C., Hartmann, W., Richter, R., Keyver-Paik, M.D., Oberhoff, C., Heinrich, G., du Bois, A., Olbrich, C., Simon, E., Friese, K., Kimmig, R., Boehmer, D., Lichtenegger, W., and Kuemmel, S.

Published
2012
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19. FDG-PET/CT-basierte Radiomics und progressionsfreies Überleben beim nicht-kleinzelligen Lungenkarzinom

Author

Rogasch, J., additional, Lugani, E., additional, Baumgärtner, G.L., additional, Frost, N., additional, Neudecker, J., additional, Rückert, J., additional, Schmidt, B., additional, Schneider, P., additional, Böhmer, D., additional, Ochsenreither, S., additional, Amthauer, H., additional, Penzkofer, T., additional, and Furth, C., additional

Published
2022
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23. Very long term outcomes, time patterns of recurrence and other-cause mortality in patients treated with salvage radiation therapy for recurrent prostate cancer after radical prostatectomy: implications for risk tailored follow-up strategies

Author

Giuseppe, C., primary, Fossati, N., additional, Stabile, A., additional, Martini, A., additional, Karnes, R.J., additional, Boorjan, S.A., additional, Bossi, A., additional, Di Muzio, N., additional, Cozzarini, C., additional, Gandaglia, G., additional, Bartkowiak, D., additional, Böhmer, D., additional, Shariat, S., additional, Goldner, G., additional, Devos, G., additional, Joniau, S., additional, Berghen, C., additional, De Meerleer, G., additional, Van Poppel, H., additional, Necchi, A., additional, Montorsi, F., additional, Wiegel, T., additional, and Briganti, A., additional

Published
2021
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27. Very long-term outcomes, time patterns of recurrence and other-cause mortality in patients treated with salvage radiation therapy for recurrent prostate cancer after radical prostatectomy: Implications for risk tailored follow-up strategies

Author

Mazzone, E., primary, Fossati, N., additional, Stabile, A., additional, Martini, A., additional, Karnes, R.J., additional, Boorjan, S.A., additional, Bossi, A., additional, Di Muzio, N., additional, Cozzarini, C., additional, Gandaglia, G., additional, Bartkowiak, D., additional, Böhmer, D., additional, Shariat, S., additional, Goldner, G., additional, Devos, G., additional, Joniau, S., additional, Berghen, C., additional, De Meerleer, G., additional, Van Poppel, H., additional, Necchi, A., additional, Montorsi, F., additional, Wiegel, T., additional, and Briganti, A., additional

Published
2021
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28. EAU BCR risk classification as decision tool for salvage radiotherapy? A multicenter study

Author

Preisser, F., primary, Abrams-Pompe, R.S., additional, Stelwagen, P.J., additional, Böhmer, D., additional, Zattoni, F., additional, Magli, A., additional, Gómez Rivas, J., additional, Vives Dilme, R., additional, Sepulcri, M., additional, Eguibar, A., additional, Heidegger, I., additional, Arnold, C., additional, Fankhauser, C.D., additional, Chun, F.K.H., additional, Van Der Poel, H., additional, Gandaglia, G., additional, Wiegel, T., additional, Van Den Bergh, R.C.N., additional, and Tilki, D., additional

Published
2021
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32. FDG-PET/CT für das prätherapeutische Lymphknotenstaging beim nicht-kleinzelligen Lungenkarzinom: Ein Vorschlag für modifizierte Leitlinienempfehlungen

Author

Rogasch, J, additional, Frost, N, additional, Michaels, L, additional, Penzkofer, T, additional, Temmesfeld-Wollbrück, B, additional, Neudecker, J, additional, Rückert, J, additional, Böhmer, D, additional, Gerhold, M, additional, Ochsenreither, S, additional, Amthauer, H, additional, and Furth, C, additional

Published
2021
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33. Validation of an independent prognostic value of the asphericity of F18-fluorodeoxyglucose (FDG) uptake in non-small cell lung cancer (NSCLC) patients undergoing treatment in curative intent

Author

Rogasch, J., Furth, C., Chibolela, C., Hofheinz, F., Ochsenreither, S., Rückert, J., Neudecker, J., Böhmer, D., Laffert, M., Amthauer, H., and Frost, N.

Subjects
Prognosis, FDG-PET, survival, quantification, metabolic tumor volume
Abstract

Background In patients with non-small cell lung cancer (NSCLC), asphericity (ASP) of the primary tumor’s metabolic tumor volume (MTV) has shown prognostic significance. This study aimed at validation in an independent, sufficiently large cohort. Patients and Methods Retrospective study in 311 NSCLC patients undergoing FDG-PET/CT before curatively intended treatment (always including surgery). 140 patients had UICC stage I, 78 stage II, and 93 stage III (adenocarcinoma [ADC]:153; squamous cell carcinoma [SCC]:141). Primary tumor MTV was delineated with semiautomated background-adapted threshold relative to SUVmax. Cox regression (PFS/OS) for PET (MTV, ASP, SUVmax), clinical (T/N descriptor, UICC stages), histological and treatment variables (Rx/1 vs. R0 resection, chemotherapy/radiotherapy yes/no). Results Events (progression/relapse) occurred in 167/311 patients, 137 died (median survivor follow-up, 37 months). In multivariable Cox regression for OS, ASP>33.3% (HR, 1.58 [1.04-2.39]), male sex (1.84), age (1.04 per year), EGOG≥2 vs. 0/1 (2.68), stage II vs. I (1.96), and Rx/1 vs. R0 resection (2.1) were significant. Among separate UICC stages, ASP only predicted OS in stage II (optimal, >19.5%; median OS, 33 vs. 59 months). Regarding PFS, ASP>21.2%, male sex, EGOG≥2, stage II vs. I, and Rx/1 resection were prognostic. ASP remained prognostic in stage II (optimal, >19.5%; PFS, 12 vs. 47 months). Log-rank test for ASP was significant at any cut-off ≥18% (OS) or from 9-59% (PFS). Conclusion ASP was validated as prognostic factor for PFS and OS in patients with NSCLC and curative treatment intent, especially stage II. High ASP in stage II could imply intensified treatment or intensified follow-up.

Published
2020

39. EAU BCR risk classification as decision tool for salvage radiatiotherapy

Author

Pompe, R.S., primary, Wiegel, T., additional, Bartkowiak, D., additional, Preisser, F., additional, Leyh-Bannurah, S., additional, Gild, P., additional, Salomon, G., additional, Graefen, M., additional, Siegmann, A., additional, Böhmer, D., additional, Budach, V., additional, Fisch, M., additional, Huland, H., additional, and Tilki, D., additional

Published
2020
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42. Validation of an independent prognostic value of the asphericity of FDG uptake in non-small cell cancer patients undergoing treatment in curative intent

Author

Rogasch, J., Chibolela, C., Frost, N., Wedel, F., Hofheinz, F., Rückert, J., Neudecker, J., Böhmer, D., Laffert, M., Amthauer, H., Furth, C., Rogasch, J., Chibolela, C., Frost, N., Wedel, F., Hofheinz, F., Rückert, J., Neudecker, J., Böhmer, D., Laffert, M., Amthauer, H., and Furth, C.

Abstract

Ziel/Aim: In patients with non-small cell lung cancer (NSCLC) undergoing treatment with curative intent, the asphericity (ASP) of the primary tumor’s metabolic tumor volume (MTV) has been demonstrated as a prognostic factor. This study aimed at validation in an independent cohort with sufficient sample size. Methodik/Methods: Retrospective study in 313 NSCLC patients (203 men; median age, 67 [41-87] a) undergoing FDG-PET/CT with the same scanner prior to treatment in curative intent (always including resection of the primary tumor). 137 patients had UICC stage I, 79 patients stage II and 97 patients stage III disease (adenocarcinoma [ADC], 153; squamous cell carcinoma [SCC], 143, other, 17). Delineation of primary tumor MTV with semiautomated background-adapted threshold relative to its SUVmax. Univariable Cox regression for progression-free (PFS) and overall survival (OS) for PET parameters (MTV, ASP, SUVmax, SUVmean), clinical (UICC stage I vs. II vs. III), histological (SCC vs. ADC) and treatment variables (Rx/1 vs. R0 resection, chemotherapy yes/no, radiotherapy yes/no). Multivariable Cox of parameters significant in univariate Cox. Ergebnisse/Results: Events (progression, relapse, death) occurred in 169/313 patients, 139 patients died (median follow-up in survivors, 37 months). In multivariable Cox for OS, ASP >33.3% (hazard ratio [HR], 1.53 [95%-confidence interval, 1.02-2.3]), Rx/1 vs. R0 resection (HR, 2.47 [1.5-4.2]) and SCC vs. ADC (HR, 1.53 [1.1-2.2]) were significant. Log-rank test for ASP was significant at any cut-off from 18% upwards. Among separate UICC stages, ASP was only prognostic for OS in stage II (optimal, >19.5%; median OS, 33 vs. 59 months; p<0.01). In multivariable Cox for PFS, ASP >21.2% (HR, 1.75 [1.2-2.5]) and Rx/1 vs. R0 (HR, 2.48 [1.5-4.1]) were significant. Log-rank test for ASP was significant at any cut-off from 10-60%. Schlussfolgerungen/Conclusions: ASP was validated as an independent predictor of PFS and OS in NSCLC patients with

Published
2019

46. There is no way to compensate for a non-timely use of salvage radiation therapy in men with recurrent prostate cancer after radical prostatectomy

Author

Bianchi, M., primary, Fossati, N., additional, Karnes, R., additional, Boorjian, S., additional, Boeri, L., additional, Bossi, A., additional, Di Muzio, N., additional, Cozzarini, C., additional, Chiorda, B. Noris, additional, Mazzone, E., additional, Gandaglia, G., additional, Bartkowiak, D., additional, Böhmer, D., additional, Shariat, S., additional, Goldner, G., additional, Battaglia, A., additional, Joniau, S., additional, Haustermans, K., additional, De Meerleer, G., additional, Fonteyne, V., additional, Ost, P., additional, Van Poppel, H., additional, Montorsi, F., additional, Wiegel, T., additional, and Briganti, A., additional

Published
2019
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49. Assessing the impact and predictors of other-cause mortality in patients treated with post-prostatectomy salvage radiation therapy in order to avoid possible overtreatment: Results from a large, multi-institutional study

Author

Mazzone, E., primary, Fossati, N., additional, Karnes, R.J., additional, Boorjian, S.A., additional, Luca, B., additional, Bossi, A., additional, Di Muzio, N., additional, Cozzarini, C., additional, Noris Chiorda, B., additional, Gandaglia, G., additional, Scuderi, S., additional, Bartkowiak, D., additional, Böhmer, D., additional, Shariat, S., additional, Goldner, G., additional, Battaglia, A., additional, Joniau, S., additional, Haustermans, K., additional, De Meerleer, G., additional, Fonteyne, V., additional, Ost, P., additional, Van Poppel, H., additional, Montorsi, F., additional, Wiegel, T., additional, and Briganti, A., additional

Published
2019
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50. What is the best definition of biochemical response to salvage radiation therapy in prostate cancer patients treated for PSA rising after radical prostatectomy? Results from a multi-institutional series

Author

Fossati, N., primary, Karnes, R.J., additional, Boorjian, S.A., additional, Boeri, L., additional, Bossi, A., additional, Di Muzio, N., additional, Cozzarini, C., additional, Noris Chiorda, B., additional, Mazzone, E., additional, Gandaglia, G., additional, Barletta, F., additional, Bartkowiak, D., additional, Böhmer, D., additional, Shariat, S., additional, Goldner, G., additional, Battaglia, A., additional, Joniau, S., additional, Haustermans, K., additional, De Meerleer, G., additional, Fonteyne, V., additional, Ost, P., additional, Van Poppel, H., additional, Montorsi, F., additional, Wiegel, T., additional, and Briganti, A., additional

Published
2019
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