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1. A snapshot of pediatric inpatients and outpatients with COVID-19: a point prevalence study from Turkey

Author

Yılmaz, Dilek, Üstündağ, Gülnihan, Büyükçam, Ayşe, Salı, Enes, Çelik, Ümit, Avcu, Gülhadiye, Belet, Nurşen, Çakmak Taşkın, Esra, Öcal Demir, Sevliya, Birbilen, Ahmet Ziya, Kılıç, Ömer, Metin Akcan, Özge, Tekin Yılmaz, Ayşe, Aldemir Kocabaş, Bilge, Hatipoğlu, Nevin, Karbuz, Adem, Çakır, Deniz, Sütçü, Murat, Aygün, Fatma Deniz, Çelik, Taylan, Bayturan Şen, Semra, Dalgıç, Nazan, Ümit, Zühal, Kara, Soner Sertan, Karadağ Öncel, Eda, Bolat, Ahmet, Kılıç Çil, Merve, Turan, Caner, Çakıl Güzin, Ayşe, Topal, Sevgi, Esen Besli, Gülser, Doğan, Gizem, Şahin, Sabiha, Akın, Fatih, Bildirici, Yaşar, Timurtaş Dayar, Gülperi, Ergül Sarı, Emine, Kızmaz İşançlı, Didem, Kara, Manolya, Önal, Pınar, Aylaç, Hakan, Lüleci, Duygu, Yaşar, Belma, Dede, Elif, Çağlar, Aykut, Akova, Sevgi, Afat Turgut, Elif, Yazıcı Özkaya, Pınar, Kandemir Gülmez, Tuğba, Ulusoy, Emel, Duyu, Muhterem, Kara, Yalçın, Çeliktaş, Hüseyin, Tekeli, Onur, Çağlar, Fatma, Gül, Doruk, Oral Cebeci, Sinem, Battal, Fatih, Bal, Alkan, Aygün, Emre, Uysalol, Metin, Arslan, Gazi, Özkavaklı, Ayberk, Kızıl, Mahmut Can, Yazar, Abdullah, Aygün, Fatih, Somer, Ayper, Kuyucu, Necdet, Dinleyici, Ener Çağrı, and Kara, Ateş

Published
2023
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5. The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media

Author

Kara, Ateş, Büyükcam, Ayşe, Sütçü, Murat, Sali, Enes, Bozdemir, Şefika Elmas, Kara, Manolya, İlarslan, Eda Çullas, Kaya, Cemil, Karakaşlılar, Sabahat, Sönmez, Gülsüm, Kara, Soner Sertan, Bedir, Tuğba, Albayrak, Eda, Kara, Tuğçe Tural, Çelebi, Solmaz, Öz, Fatma Nur, Karbuz, Adem, Somer, Ayper, Alabaz, Derya, Tezer, Hasan, Özdemir, Halil, and Çiftçi, Ergin

Published
2022
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6. SARS-CoV-2 seropositivity among pediatric health care personnel after the first peak of the pandemic: nationwide surveillance in Turkey

Author

Oygar, Pembe Derin, Büyükçam, Ayşe, Bal, Zümrüt Şahbudak, Dalgıç, Nazan, Bozdemir, Şefika Elmas, Karbuz, Adem, Çetin, Benhur Şirvan, Kara, Yalçın, Çetin, Ceren, Hatipoğlu, Nevin, Uygun, Hatice, Aygün, Fatma Deniz, Törün, Selda Hançerli, Okur, Dicle Şener, Çiftdoğan, Dilek Yılmaz, Kara, Tuğçe Tural, Yahşi, Aysun, Özer, Arife, Demir, Sevliya Öcal, Akkoç, Gülşen, Turan, Cansu, Salı, Enes, Şen, Semra, Erdeniz, Emine Hafize, Kara, Soner Sertan, Emiroğlu, Melike, Erat, Tuğba, Aktürk, Hacer, Gürlevik, Sibel Laçinel, Sütçü, Murat, Aydın, Zeynep Gökçe Gayretli, Atikan, Başak Yıldız, Yeşil, Edanur, Güner, Gizem, Çelebi, Emel, Efe, Kadir, İşançlı, Didem Kızmaz, Durmuş, Habibe Selver, Tekeli, Seher, Karaaslan, Ayşe, Bülbül, Lida, Almış, Habip, Kaba, Özge, Keleş, Yıldız Ekemen, Yazıcıoğlu, Bahadır, Oğuz, Şerife Bahtiyar, Ovalı, Hüsnü Fahri, Doğan, Hazal Helin, Çelebi, Solmaz, Çakır, Deniz, Karasulu, Burcugül, Alkan, Gülsüm, Yenidoğan, İrem, Gül, Doruk, Küçükalioğlu, Burcu Parıltan, Avcu, Gülhadiye, Kukul, Musa Gürel, Bilen, Melis, Yaşar, Belma, Üstün, Tuğba, Kılıç, Ömer, Akın, Yasemin, Cebeci, Sinem Oral, Bucak, Ibrahim Hakan, Yanartaş, Mehpare Sarı, Şahin, Aslıhan, Arslanoğlu, Sertaç, Elevli, Murat, Çoban, Rabia, Öz, Şadiye Kübra Tüter, Hatipoğlu, Halil, Erkum, İlyas Tolga, Turgut, Mehmet, Demirbuğa, Asuman, Özçelik, Taha, Çiftçi, Diclehan, Sarı, Emine Ergül, Akkuş, Gökhan, Hatipoğlu, Sadık Sami, Dinleyici, Ener Çağrı, Hacımustafaoğlu, Mustafa, Özkınay, Ferda, Kurugöl, Zafer, Cengiz, Ali Bülent, Somer, Ayper, Tezer, Hasan, and Kara, Ateş

Published
2021
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10. Pediatricians′ attitudes in management of acute otitis media and ear pain in Turkey

Author

Büyükcam, Ayşe, Kara, Ateş, Bedir, Tuğba, Gülhan, Belgin, Özdemir, Halil, Sütçü, Murat, Düzgöl, Mine, Arslan, Aslı, Tekin, Tuna, Çelebi, Solmaz, Kukul, Musa Gürel, Bayhan, Gülsüm İclal, Köşker, Muhammet, Karbuz, Adem, Çelik, Melda, Kocabay Sütçü, Zümrüt, Metin, Özge, Karakaşlılar, Sebahat, Dağlı, Abdullah, Kara, Soner Sertan, Albayrak, Eda, Kanık, Saliha, Tezer, Hasan, Parlakay, Aslınur, Çiftci, Ergin, Somer, Ayper, Devrim, İlker, Kurugöl, Zafer, Dinleyici, Ener Çağrı, and Atla, Pınar

Published
2018
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11. Evaluation of vaccination status of health care workers for recommended vaccines and their acceptance of SARS-CoV-2 vaccines

Author

Oygar, Pembe Derin, primary, Büyükçam, Ayşe, additional, Sahbudak Bal, Zumrut, additional, Dalgıç, Nazan, additional, Bozdemir, Şefika Elmas, additional, Karbuz, Adem, additional, Çetin, Benhur Şirvan, additional, Kara, Yalçın, additional, Çetin, Ceren, additional, Hatipoğlu, Nevin, additional, Uygun, Hatice, additional, Aygün, Fatma Deniz, additional, Hançerli Törün, Selda, additional, Şener Okur, Dicle, additional, Yılmaz Çiftdoğan, Dilek, additional, Tural Kara, Tuğçe, additional, Yahşi, Aysun, additional, Özer, Arife, additional, Öcal Demir, Sevliya, additional, Akkoç, Gülşen, additional, Turan, Cansu, additional, Salı, Enes, additional, Şen, Semra, additional, Erdeniz, Emine Hafize, additional, Kara, Soner Sertan, additional, Emiroğlu, Melike, additional, Erat, Tuğba, additional, Aktürk, Hacer, additional, Laçinel Gürlevik, Sibel, additional, Sütçü, Murat, additional, Gayretli Aydın, Zeynep Gökçe, additional, Yıldız Atikan, Başak, additional, Yeşil, Edanur, additional, Güner Özenen, Gizem, additional, Çelebi, Emel, additional, Efe, Kadir, additional, Kizmaz isancli, Didem, additional, Selver Durmuş, Habibe, additional, Tekeli, Seher, additional, Karaaslan, Ayşe, additional, Bülbül, Lida, additional, Almış, Habip, additional, Kaba, Özge, additional, Ekemen Keleş, Yıldız, additional, Yazıcıoğlu, Bahadır, additional, Bahtiyar Oğuz, Serife, additional, Ovalı, Hüsnü Fahri, additional, Doğan, Hazal Helin, additional, Çelebi, Solmaz, additional, Çakir, Deniz, additional, Karasulu, Burcugül, additional, Alkan, Gülsüm, additional, Yenidoğan, İrem, additional, Gül, Doruk, additional, Parıltan Kücükalioğlu, Burcu, additional, Avcu, Gülhadiye, additional, Kukul, Musa Gürel, additional, Bilen, Melis, additional, Yaşar, Belma, additional, Üstün, Tuğba, additional, Kılıç, Ömer, additional, Akın, Yasemin, additional, Oral Cebeci, Sinem, additional, Bucak, İbrahim Hakan, additional, Sarı Yanartaş, Mehpare, additional, Şahin, Aslıhan, additional, Arslanoglu, Sertaç, additional, Elevli, Murat, additional, Çoban, Rabia, additional, Tuter Öz, Sadiye Kübra, additional, Hatipoğlu, Halil, additional, Erkum, İlyas Tolga, additional, Turgut, Mehmet, additional, Demirbuğa, Asuman, additional, Özçelik, Taha, additional, Çiftçi, Diclehan, additional, Sarı, Emine Ergül, additional, Akkuş, Gökhan, additional, Hatipoğlu, Sadık Sami, additional, Dinleyici, Ener Cağrı, additional, Hacimustafaoğlu, Mustafa, additional, Özkınay, Ferda, additional, Kurugöl, Zafer, additional, Cengiz, Ali Bulent, additional, Somer, Ayper, additional, Tezer, Hasan, additional, and Kara, Ateş, additional

Published
2022
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12. COVID-19 associated multisystemic inflammatory syndrome in 614 children with and without overlap with Kawasaki disease-Turk MIS-C study group

Author

Aktürk, Hacer, Çiftdoğan, Dilek Yılmaz; Keleş, Yıldız Ekemen; Çetin, Benhur Şirvan; Karabulut, Nazan Dalgıç; Emiroğlu, Melike; Bağcı, Zafer; Büyükçam, Ayşe; Erdeniz, Emine Hafize; Arga, Gül; Yeşil, Edanur; Çakıcı, Özlem; Karbuz, Adem; Bal, Zümrüt Şahbudak; Kara, Soner Sertan; Özer, Arife; Akcan, Özge Metin; Bozdemir, Şefika Elmas; Anıl, Ayşe Berna; Uygun, Hatice; Kılıç, Ömer; Torun, Selda Hancerli; Ümit, Zuhal; Sütcü, Murat; Özmen, Berfin ÖzgÖkce; Asrak, Hatice Karaoğlu; Alkan, Gülsüm; Aksay, Ahu Kara; Uğur, Cüneyt; Birbilen, Ahmet Ziya; Duramaz, Burcu Bursal; Özkan, Esra Akyüz; Burakay, Özgür; Arslan, Sema Yıldırım; Öncel, Eda Karadağ; Celik, Serkan Fazlı; Kılıç, Ahmet Osman; Özen, Seval; Sarıkaya, Remzi; Demirkol, Demet; Arslan, Gazi; Türel, Özden; Sert, Ahmet; Sarı, Ergül; Orbak, Zerrin; Şahin, İrfan Oğuz; Varan, Celal; Öz, Sadiye Kübra Tuter; Durak, Fatih; Oflaz, Mehmet Burhan; Kara, Manolya; Karpuz, Derya; Petmezci, Mey Talip; Hatipoğlu, Nevin; Öncel, Selim; Turgut, Mehmet; Elmalı, Ferhan; Somer, Ayper; Kuyucu, Necdet; Dinleyici, Ener Cağrı; Kurugöl, Zafer; Çiftci, Ergin; Kara, Ateş, Koç University Hospital, Aktürk, Hacer, Çiftdoğan, Dilek Yılmaz; Keleş, Yıldız Ekemen; Çetin, Benhur Şirvan; Karabulut, Nazan Dalgıç; Emiroğlu, Melike; Bağcı, Zafer; Büyükçam, Ayşe; Erdeniz, Emine Hafize; Arga, Gül; Yeşil, Edanur; Çakıcı, Özlem; Karbuz, Adem; Bal, Zümrüt Şahbudak; Kara, Soner Sertan; Özer, Arife; Akcan, Özge Metin; Bozdemir, Şefika Elmas; Anıl, Ayşe Berna; Uygun, Hatice; Kılıç, Ömer; Torun, Selda Hancerli; Ümit, Zuhal; Sütcü, Murat; Özmen, Berfin ÖzgÖkce; Asrak, Hatice Karaoğlu; Alkan, Gülsüm; Aksay, Ahu Kara; Uğur, Cüneyt; Birbilen, Ahmet Ziya; Duramaz, Burcu Bursal; Özkan, Esra Akyüz; Burakay, Özgür; Arslan, Sema Yıldırım; Öncel, Eda Karadağ; Celik, Serkan Fazlı; Kılıç, Ahmet Osman; Özen, Seval; Sarıkaya, Remzi; Demirkol, Demet; Arslan, Gazi; Türel, Özden; Sert, Ahmet; Sarı, Ergül; Orbak, Zerrin; Şahin, İrfan Oğuz; Varan, Celal; Öz, Sadiye Kübra Tuter; Durak, Fatih; Oflaz, Mehmet Burhan; Kara, Manolya; Karpuz, Derya; Petmezci, Mey Talip; Hatipoğlu, Nevin; Öncel, Selim; Turgut, Mehmet; Elmalı, Ferhan; Somer, Ayper; Kuyucu, Necdet; Dinleyici, Ener Cağrı; Kurugöl, Zafer; Çiftci, Ergin; Kara, Ateş, and Koç University Hospital

Abstract

Multisystemic inflammatory syndrome (MIS-C) diagnosis remains difficult because the clinical features overlap with Kawasaki disease (KD). The study aims to highlight the clinical and laboratory features and outcomes of patients with MISC whose clinical manifestations overlap with or without KD. This study is a retrospective analysis of a case series designed for patients aged 1 month to 18 years in 28 hospitals between November 1, 2020, and June 9, 2021. Patient demographics, complaints, laboratory results, echocardiographic results, system involvement, and outcomes were recorded. A total of 614 patients were enrolled; the median age was 7.4 years (interquartile range (IQR) 3.9-12 years). A total of 277 (45.1%) patients with MIS-C had manifestations that overlapped with KD, including 92 (33.3%) patients with complete KD and 185 (66.7%) with incomplete KD. Lymphocyte and platelet counts were significantly lower in patients with MISC, overlapped with KD (lymphocyte count 1080 vs. 1280 cells x mu L, p = 0.028; platelet count 166 vs. 216 cells x 10(3)/mu L, p < 0.001). The median serum procalcitonin levels were statistically higher in patients overlapped with KD (3.18 vs. 1.68 mu g/L, p = 0.001). Coronary artery dilatation was statistically significant in patients with overlap with KD (13.4% vs. 6.8%, p = 0.007), while myocarditis was significantly more common in patients without overlap with KD features (2.6% vs 7.4%, p = 0.009). The association between clinical and laboratory findings and overlap with KD was investigated. Age > 12 years reduced the risk of overlap with KD by 66% (p < 0.001, 95% CI 0.217-0.550), lethargy increased the risk of overlap with KD by 2.6-fold (p = 0.011, 95% CI 1.244-5.439), and each unit more albumin (g/dl) reduced the risk of overlap with KD by 60% (p < 0.001, 95% CI 0.298-0.559). Conclusion: Almost half of the patients with MISC had clinical features that overlapped with KD; in particular, incomplete KD was present. The median age was low, NA

Published
2022

13. SARS-CoV-2 seropositivity among pediatric health care personnel just after the first peak of pandemic: A nationwide surveillance

Author

Gürlevik, Sibel Laçinel, Kaba, Özge, Aktürk, Hacer, Erkum, İlyas Tolga, Turgut, Mehmet, Demirbuğa, Asuman, Keleş, Yıldız Ekemen, Yazıcıoğlu, Bahadır, Hacımustafaoğlu, Mustafa, Dinleyici, Ener Çağrı, Erat, Tuğba, Emiroğlu, Melike, Üstün, Tuğba, Kara, Soner Sertan, Doğan, Hazal Helin, Erdeniz, Emine Hafize, İşançlı, Didem Kızmaz, Yanartaş, Mehpare Sarı, Efe, Kadir, Çetin, Ceren, Dalgıç, Nazan, Büyükçam, Ayşe, Oygar, Pembe Derin, Yaşar, Belma, Ovalı, Hüsnü Fahri, Özçelik, Taha, Bilen, Melis, Bal, Zümrüt Şahbudak, Kukul, Musa Gürel, Özkınay, Ferda, Küçükalioğlu, Burcu Parıltan, Gül, Doruk, Avcu, Gülhadiye, Bozdemir, Şefika Elmas, Yenidoğan, İrem, Alkan, Gülsüm, Çiftçi, Diclehan, Şen, Semra, Kılıç, Ömer, Karbuz, Adem, Güner, Gizem, Yeşil, Edanur, Tezer, Hasan, Salı, Enes, Karasulu, Burcugül, Atikan, Başak Yıldız, Turan, Cansu, Akkoç, Gülşen, Demir, Sevliya Öcal, Oğuz, Şerife Bahtiyar, Çelebi, Solmaz, Özer, Arife, Yahşi, Aysun, Kara, Tuğçe Tural, Çiftdoğan, Dilek Yılmaz, Okur, Dicle Şener, Törün, Selda Hançerli, Akkuş, Gökhan, Hatipoğlu, Sadık Sami, Sarı, Emine Ergül, Arslanoğlu, Sertaç, Şahin, Aslıhan, Öz, Şadiye Kübra Tüter, Çelebi, Emel, Aydın, Zeynep Gökçe Gayretli, Hatipoğlu, Halil, Sütçü, Murat, Durmuş, Habibe Selver, Tekeli, Seher, Karaaslan, Ayşe, Bülbül, Lida, Almış, Habip, Cebeci, Sinem Oral, Akın, Yasemin, Kurugöl, Zafer, Aygün, Fatma Deniz, Kara, Ateş, Somer, Ayper, Cengiz, Ali Bülent, Uygun, Hatice, Çoban, Rabia, Elevli, Murat, Çakır, Deniz, Hatipoğlu, Nevin, Kara, Yalçın, Bucak, Ibrahim Hakan, and Çetin, BENHUR ŞİRVAN

Subjects
COVID-1, personnel protective equipment use, Turkey, SARS-CoV-2, Health Personnel, serology, COVID-19, Antibodies, Viral, Article, Seroepidemiologic Studies, Humans, Child, Delivery of Health Care, Pandemics, SARS Co-V-2, healthcare personnel
Abstract

Understanding SARS-CoV-2 seroprevalence among health care personnel is important to explore risk factors for transmission, develop elimination strategies and form a view on the necessity and frequency of surveillance in the future.We enrolled 4927 health care personnel working in pediatric units at 32 hospitals from 7 different regions of Turkey in a study to determine SARS Co-V-2 seroprevalence after the first peak of the COVID-19 pandemic. A point of care serologic lateral flow rapid test kit for immunoglobulin (Ig)M/IgG was used. Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed.SARS-CoV-2 seropositivity prevalence in health care personnel tested was 6.1%. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19-positive co-worker increased the likelihood of infection. The least and the most experienced personnel were more likely to be infected. Most of the seropositive health care personnel (68.0%) did not suspect that they had previously had COVID-19.Health surveillance for health care personnel involving routine point-of-care nucleic acid testing and monitoring personal protective equipment adherence are suggested as important strategies to protect health care personnel from COVID-19 and reduce nosocomial SARS-CoV-2 transmission.

Published
2021

16. Education of Healthcare Personnel Working with Pediatric Patients During COVID-19 Pandemic within the Framework of Infection Control

Author

Oygar, Pembe Derin, primary, Büyükçam, Ayşe, additional, Şahbudak Bal, Zümrüt, additional, Dalgıç, Nazan, additional, Bozdemir, Şefika Elmas, additional, Karbuz, Adem, additional, Çetin, Benhur Şirvan, additional, Kara, Yalçın, additional, Çetin, Ceren, additional, Hatipoğlu, Nevin, additional, Uygun, Hatice, additional, Aygün, Fatma Deniz, additional, Hançerli Törün, Selda, additional, Şener Okur, Dicle, additional, Yılmaz Çiftdoğan, Dilek, additional, Tural Kara, Tuğçe, additional, Yahşi, Aysun, additional, Özer, Arife, additional, Öcal Demir, Sevliya, additional, Akkoç, Gülşen, additional, Turan, Cansu, additional, Salı, Enes, additional, Şen, Semra, additional, Erdeniz, Emine Hafize, additional, Kara, Soner Sertan, additional, Emiroğlu, Melike, additional, Erat, Tuğba, additional, Aktürk, Hacer, additional, Laçinel Gürlevik, Sibel, additional, Sütçü, Murat, additional, Gayretli Aydın, Zeynep Gökçe, additional, Atikan, Başak Yıldız, additional, Yeşil, Edanur, additional, Güner, Gizem, additional, Çelebi, Emel, additional, Efe, Kadir, additional, Kızmaz İşançlı, Didem, additional, Durmuş, Habibe Selver, additional, Tekeli, Seher, additional, Karaarslan, Ayşe, additional, Bülbül, Lida, additional, Almış, Habip, additional, Kaba, Özge, additional, Ekemen Keleş, Yıldız, additional, Yazıcıoğlu, Bahadır, additional, Bahtiyar Oğuz, Şerife, additional, Ovalı, Hüsnü Fahri, additional, Doğan, Hazal Helin, additional, Çelebi, Solmaz, additional, Çakır, Deniz, additional, Karasulu, Burcugül, additional, Alkan, Gülsüm, additional, Yenidoğan, İrem, additional, Gül, Doruk, additional, Parıltan Küçükalioğlu, Burcu, additional, Avcu, Gülhadiye, additional, Kukul, Musa Gürel, additional, Bilen, Melis, additional, Yaşar, Belma, additional, Üstün, Tuğba, additional, Kılıç, Ömer, additional, Akın, Yasemin, additional, Oral Cebeci, Sinem, additional, Turgut, Mehmet, additional, Sarı Yanartaş, Mehpare, additional, Şahin, Aslıhan, additional, Arslanoğlu, Sertaç, additional, Elevli, Murat, additional, Tüter Öz, Şadiye Kübra, additional, Hatipoğlu, Halil, additional, Erkum, İlyas Tolga, additional, Demirbuğa, Asuman, additional, Özçelik, Taha, additional, Ergül Sarı, Emine, additional, Akkuş, Gökhan, additional, Hatipoğlu, Sadık Sami, additional, Dinleyici, Ener Çağrı, additional, Hacımustafaoğlu, Mustafa, additional, Özkınay, Ferda, additional, Kurugöl, Zafer, additional, Cengiz, Ali Bülent, additional, Somer, Ayper, additional, Tezer, Hasan, additional, and Kara, Ateş, additional

Published
2020
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17. COVID-19 Pandemisinde Enfeksiyon Kontrol Çalışmaları Çerçevesinde Çocuk Hastalarla Çalışan Sağlık Personeli Eğitimi

Author

Oygar, Pembe Derin, primary, Büyükçam, Ayşe, additional, Şahbudak Bal, Zümrüt, additional, Dalgıç, Nazan, additional, Bozdemir, Şefika Elmas, additional, Karbuz, Adem, additional, Çetin, Benhur Şirvan, additional, Kara, Yalçın, additional, Çetin, Ceren, additional, Hatipoğlu, Nevin, additional, Uygun, Hatice, additional, Aygün, Fatma Deniz, additional, Hançerli Törün, Selda, additional, Şener Okur, Dicle, additional, Yılmaz Çiftdoğan, Dilek, additional, Tural Kara, Tuğçe, additional, Yahşi, Aysun, additional, Özer, Arife, additional, Öcal Demir, Sevliya, additional, Akkoç, Gülşen, additional, Turan, Cansu, additional, Salı, Enes, additional, Şen, Semra, additional, Erdeniz, Emine Hafize, additional, Kara, Soner Sertan, additional, Emiroğlu, Melike, additional, Erat, Tuğba, additional, Aktürk, Hacer, additional, Laçinel Gürlevik, Sibel, additional, Sütçü, Murat, additional, Gayretli Aydın, Zeynep Gökçe, additional, Atikan, Başak Yıldız, additional, Yeşil, Edanur, additional, Güner, Gizem, additional, Çelebi, Emel, additional, Efe, Kadir, additional, Kızmaz İşançlı, Didem, additional, Durmuş, Habibe Selver, additional, Tekeli, Seher, additional, Karaarslan, Ayşe, additional, Bülbül, Lida, additional, Almış, Habip, additional, Kaba, Özge, additional, Ekemen Keleş, Yıldız, additional, Yazıcıoğlu, Bahadır, additional, Bahtiyar Oğuz, Şerife, additional, Ovalı, Hüsnü Fahri, additional, Doğan, Hazal Helin, additional, Çelebi, Solmaz, additional, Çakır, Deniz, additional, Karasulu, Burcugül, additional, Alkan, Gülsüm, additional, Yenidoğan, İrem, additional, Gül, Doruk, additional, Parıltan Küçükalioğlu, Burcu, additional, Avcu, Gülhadiye, additional, Kukul, Musa Gürel, additional, Bilen, Melis, additional, Yaşar, Belma, additional, Üstün, Tuğba, additional, Kılıç, Ömer, additional, Akın, Yasemin, additional, Oral Cebeci, Sinem, additional, Bucak, İbrahim Hakan, additional, Turgut, Mehmet, additional, Sarı Yanartaş, Mehpare, additional, Şahin, Aslıhan, additional, Arslanoğlu, Sertaç, additional, Elevli, Murat, additional, Tüter Öz, Şadiye Kübra, additional, Hatipoğlu, Halil, additional, Erkum, İlyas Tolga, additional, Demirbuğa, Asuman, additional, Özçelik, Taha, additional, Ergül Sarı, Emine, additional, Akkuş, Gökhan, additional, Hatipoğlu, Sadık Sami, additional, Dinleyici, Ener Çağrı, additional, Hacımustafaoğlu, Mustafa, additional, Özkınay, Ferda, additional, Kurugöl, Zafer, additional, Cengiz, Ali Bülent, additional, Somer, Ayper, additional, Tezer, Hasan, additional, and Kara, Ateş, additional

Published
2020
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18. Education of healthcare personnel working with pediatric patients during COVID-19 pandemic within the framework of infection control

Author

Aktürk, Hacer; Yenidoğan, İrem, Oygar, Pembe Derin; Büyükçam, Ayşe; Bal, Zümrüt Şahbudak; Dalgıç, Nazan; Bozdemir, Şefika Elmas; Karbuz, Adem; Çetin, Benhur Şirvan; Kara, Yalçın; Çetin, Ceren; Hatipoğlu, Nevin; Uygun, Hatice; Aygün, Fatma Deniz; Törün, Selda Hançerli; Okur, Dicle Şener; Çiftdoğan, Dilek Yılmaz; Kara, Tuğçe Tural; Yahşi, Aysun; Özer, Arife; Demir, Sevliya Öcal; Akkoç, Gülşen; Turan, Cansu; Salı, Enes; Şen, Semra; Erdeniz, Emine Hafize; Kara, Soner Sertan; Emiroğlu, Melike; Erat, Tuğba; Gürlevik, Sibel Laçinel; Sütçü, Murat; Aydin, Zeynep Gökçe Gayretli; Atıkan, Başak Yıldız; Yeşil, Edanur; Güner, Gizem; Çelebi, Emel; Efe, Kadir; İşançlı, Didem Kızmaz; Durmuş, Habibe Selver; Tekeli, Seher; Karaarslan, Ayşe; Bülbül, Lida; Almiş, Habip; Kaba, Özge; Keleş, Yıldız Ekemen; Yazıcıoğlu, Bahadır; Oğuz, Şerife Bahtiyar; Ovalı, Hüsnü Fahri; Doğan, Hazal Helin; Çelebi, Solmaz; Çakır, Deniz; Karasulu, Burcugül; Alkan, Gülsüm; Gül, Doruk; Küçükalioğlu, Burcu Parıltan; Avcu, Gülhadiye; Kukul, Musa Gürel; Bilen, Melis; Yaşar, Belma; Üstün, Tuğba; Kılıç, Ömer; Akın, Yasemin; Cebeci, Sinem Oral; Turgut, Mehmet; Yanartaş, Mehpare Sarı; Şahin, Aslıhan; Arslanoğlu, Sertaç; Elevli, Murat; Öz, Şadiye Kübra Tüter; Hatipoğlu, Halil; Erkum, İlyas Tolga; Demirbuğa, Asuman; Özçelik, Taha; Sarı, Emine Ergül; Akkuş, Gökhan; Hatipoğlu, Sadık Sami; Dinleyici, Ener Cağrı; Hacımustafaoğlu, Mustafa; Özkınay, Ferda; Kurugöl, Zafer; Cengiz, Ali Bülent; Somer, Ayper; Tezer, Hasan; Kara, Ateş, Koç University Hospital, Aktürk, Hacer; Yenidoğan, İrem, Oygar, Pembe Derin; Büyükçam, Ayşe; Bal, Zümrüt Şahbudak; Dalgıç, Nazan; Bozdemir, Şefika Elmas; Karbuz, Adem; Çetin, Benhur Şirvan; Kara, Yalçın; Çetin, Ceren; Hatipoğlu, Nevin; Uygun, Hatice; Aygün, Fatma Deniz; Törün, Selda Hançerli; Okur, Dicle Şener; Çiftdoğan, Dilek Yılmaz; Kara, Tuğçe Tural; Yahşi, Aysun; Özer, Arife; Demir, Sevliya Öcal; Akkoç, Gülşen; Turan, Cansu; Salı, Enes; Şen, Semra; Erdeniz, Emine Hafize; Kara, Soner Sertan; Emiroğlu, Melike; Erat, Tuğba; Gürlevik, Sibel Laçinel; Sütçü, Murat; Aydin, Zeynep Gökçe Gayretli; Atıkan, Başak Yıldız; Yeşil, Edanur; Güner, Gizem; Çelebi, Emel; Efe, Kadir; İşançlı, Didem Kızmaz; Durmuş, Habibe Selver; Tekeli, Seher; Karaarslan, Ayşe; Bülbül, Lida; Almiş, Habip; Kaba, Özge; Keleş, Yıldız Ekemen; Yazıcıoğlu, Bahadır; Oğuz, Şerife Bahtiyar; Ovalı, Hüsnü Fahri; Doğan, Hazal Helin; Çelebi, Solmaz; Çakır, Deniz; Karasulu, Burcugül; Alkan, Gülsüm; Gül, Doruk; Küçükalioğlu, Burcu Parıltan; Avcu, Gülhadiye; Kukul, Musa Gürel; Bilen, Melis; Yaşar, Belma; Üstün, Tuğba; Kılıç, Ömer; Akın, Yasemin; Cebeci, Sinem Oral; Turgut, Mehmet; Yanartaş, Mehpare Sarı; Şahin, Aslıhan; Arslanoğlu, Sertaç; Elevli, Murat; Öz, Şadiye Kübra Tüter; Hatipoğlu, Halil; Erkum, İlyas Tolga; Demirbuğa, Asuman; Özçelik, Taha; Sarı, Emine Ergül; Akkuş, Gökhan; Hatipoğlu, Sadık Sami; Dinleyici, Ener Cağrı; Hacımustafaoğlu, Mustafa; Özkınay, Ferda; Kurugöl, Zafer; Cengiz, Ali Bülent; Somer, Ayper; Tezer, Hasan; Kara, Ateş, and Koç University Hospital

Abstract

Objective: in the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic caused by SARS-CoV-2, proved to be no exception. Many healthcare workers died in the early stages of pandemic due to inadequate precautions and insufficient protection. It is essential to protect and maintain the safety of healthcare personnel for the confinement of pandemic as well as continuity of qualified healthcare services which is already under strain. Educating healthcare personnel on appropiate use of personal protective equipment (PPE) is as essential as procuring them. Material and methods: a survey is conducted on 4927 healthcare personnel working solely with pediatric patients from 32 different centers. Education given on PPE usage were questioned and analyzed depending on age, sex, occupation and region. Results: among four thousand nine hundred twelve healthcare personnel from 32 different centers 91% (n=4457) received education on PPE usage. Of those who received education only 36% was given both theoretical and applied education. Although there was no differences among different occupation groups, receiving education depended on regions. Conclusion: it is essential to educate healthcare personnel appropiately nationwidely for the continuity of qualified healthcare services during the pandemic. / Giriş: yeni ortaya çıkan patojenlerin neden olduğu salgınların erken dönemleri sağlık çalışanları için büyük bir risk taşımaktadır. SARS-CoV-2’nin neden olduğu pandemide de durum farklı olmamış, alınan yetersiz önlemler ve kişisel korunma eksikliği nedenleriyle pandemi başlangıcında birçok sağlık çalışanı hayatını kaybetmiştir. Sağlık çalışanlarının koruması ve güvenli ortamda çalışmalarının devamlılığının sağlanması sağlık hizmetlerinin aksamamasının yanında salgının sınırlandırması içinde gereklidir. Kişisel koruyucu ekipmaların kullanımı ile ilgili eğitimlerin verilmesi, gerekli durumlarda güncellenmesi koruyucu ekipman, NA

Published
2020

19. Beş Yaş Altı Çocuklarda Akut Otitis Media Tanısı ile Antibiyotik Tercihi ve Antibiyotik Kullanımı Sonrası Gastrointestinal Sistem Yan Etkileri Çok Merkezli Prospektif Gözlemsel Çalışma

Author

TEZER, HASAN, ÇULLAS İLARSLAN, NİSA EDA, KARBUZ, ADEM, ÖZ, FATMA NUR, SÖNMEZ, GÜLSÜM, ÖZDEMİR, HALİL, ALBAYRAK, EDA, TURAL KARA, TUĞÇE, ÇELEBİ, SOLMAZ, KARA, SONER SERTAN, SALİ, ENES, ACAR, EMİNE MANOLYA, KAYA, CEMİL, BOZDEMİR, ŞEFİKA ELMAS, SÜTÇÜ, MURAT, BÜYÜKÇAM, AYŞE, SOMER, AYPER, KARA, ATEŞ, ÇİFTCİ, ERGİN, KARAKAŞLILAR, SABAHAT, ALABAZ, DERYA, and BEDİR, TUĞBA

Published
2018

20. Beş Yaş Altı Çocuklarda Akut Otitis Media’da Kulak Ağrısında Lokal Lidokainin Etkinliği ve Güvenirliği Çalışması Pediotal III Ön Sonuçları

Author

ÇİFTCİ, ERGİN, ÖZ, FATMA NUR, ÇELEBİ, SOLMAZ, ÖZDEMİR, HALİL, SOMER, AYPER, KARAKAŞLILAR, SABAHAT, ÇULLAS İLARSLAN, NİSA EDA, KAYA, CEMİL, ALBAYRAK, EDA, BEDİR, TUĞBA, SÖNMEZ, GÜLSÜM, KARA, SONER SERTAN, SALI, ENES, ACAR ÖZKÖSLÜ, MANOLYA, BOZDEMİR, ŞEFİKA ELMAS, SÜTÇÜ, MURAT, BÜYÜKÇAM, AYŞE, KARA, ATEŞ, TEZER, HASAN, and KARBUZ, ADEM

Published
2017

21. Clinical Strains ofChryseobacteriumandElizabethkingiaspp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics

Author

Mirza, Hasan Cenk, primary, Tuncer, Özlem, additional, Ölmez, Serpil, additional, Şener, Burçin, additional, Tuğcu, Gökçen Dilşa, additional, Özçelik, Uğur, additional, Gürsoy, Nafia Canan, additional, Otlu, Barış, additional, Büyükçam, Ayşe, additional, Kara, Ateş, additional, and Sancak, Banu, additional

Published
2018
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25. Türk tıp öğrencileri arasında suçiçeği aşısı kabulü ve aşı ilişkili yan etkiler konusundaki tutumlar.

Author

Özer, Murat, Büyükçam, Ayşe, Bayhan, Cihangül, Özsürekci, Yasemin, and Kara, Ateş

Abstract

Varicella-zoster virus from herpes virus family causes two different clinical presentations including chickenpox and shingles. Chickenpox is an infectious disease which can be prevented by vaccination and may cause serious complications in adults and in patients with severe immune deficiency. Medical staff without immunization are also at risk for chickenpox. Obstetric clinics, newborn clinics or clinics where the patients are treated with immunosuppressive therapy are especially important units for chickenpox and medical students work in these clinics for variable terms. It has been reported that medical students might occasionally be the source of chickenpox infection. Therefore, it is known that medical student vaccination against the chickenpox is a preventive measure for both healthcare staff and patients. This study has been conducted to evaluate the adoption of varicella vaccine and attitudes on vaccine-related side effects in medical students. 80 medical students from Hacettepe University Medical Faculty with no chickenpox or immunization history (varicella zoster IgG class antibodies were negative) were vaccinated against chickenpox between January 2014 and December 2014. A questionnaire of six questions was responded by the participants via phone call after 1 to 2 months after vaccination. Collected data were analyzed using SPSS 21.0 and data were presented by descriptive statistics and Independent- Samples T-Test. The study was completed with a total of 61 medical students consisting of 25 male (41 %) and 59 female (59%) students that were contacted by phone call. The average age of the students was 22.6 (22-24) years. Most common adverse side effect was the pain at the vaccination area (47.8%). All students agreed to take the next dose despite the side effects. 13 of the participants (21.3%) explained that the most important reason of their consent for the vaccination was because it was recommended by pediatric infectious disease specialists. 35 of the students (57.4%) expressed that they would not give consent for the vaccination if it was not free of charge. There was no discernable difference in terms of vaccination consent between males and females. More than half of the participants stated that they would back out from getting vaccinated if it was not free of charge. Some of them gave consent for vaccination after the recommendation of pediatric infectious disease specialists. According to our study, the price of vaccination and the recommendation of pediatric infectious disease specialists are important for the adoption of varicella vaccine in medical students. [ABSTRACT FROM AUTHOR]

Published
2016

26. Clinical Strains of Chryseobacterium and Elizabethkingia spp. Isolated from Pediatric Patients in a University Hospital: Performance of MALDI-TOF MS-Based Identification, Antimicrobial Susceptibilities, and Baseline Patient Characteristics.

Author

Mirza, Hasan Cenk, Tuncer, Özlem, Ölmez, Serpil, Şener, Burçin, Tuğcu, Gökçen Dilşa, Özçelik, Uğur, Gürsoy, Nafia Canan, Otlu, Barış, Büyükçam, Ayşe, Kara, Ateş, and Sancak, Banu

Subjects
*ELIZABETHKINGIA, *CHILD patients, *MATRIX-assisted laser desorption-ionization, *TIME-of-flight mass spectrometry, *MICROBIAL sensitivity tests
Abstract

Our objective was to evaluate the performance of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of the Chryseobacterium and Elizabethkingia spp. isolated from pediatric patients at Hacettepe University Hospital using 16S rRNA gene sequencing as the gold standard and to determine the antimicrobial susceptibility patterns of the isolates and baseline characteristics of patients. All stored Chryseobacterium and Elizabethkingia spp. isolated from various clinical specimens (sputum, blood, and urine) of pediatric patients at Hacettepe University Hospital between 2012 and 2016 were included in this study. Minimum inhibitory concentrations of 10 antimicrobial agents were determined by Etest for all isolates. To determine the baseline characteristics of patients, medical records of all patients were retrospectively reviewed. In total, 18 isolates of Chryseobacterium spp. (16 C. indologenes , 2 C. gleum ) and 5 isolates of Elizabethkingia spp. (3 E. meningoseptica , 2 E. anophelis ) were identified by 16S rRNA sequencing. MALDI-TOF MS correctly identified 19 (82.6%) isolates to the species level. The quinolones (ciprofloxacin and levofloxacin), trimethoprim/sulfamethoxazole and piperacillin/tazobactam showed the highest spectrum of activity against the overall collection of isolates. Cystic fibrosis (CF) was the underlying disease in 81.8% of patients. To our knowledge, this study includes the largest number of Chryseobacterium spp. isolated from clinical specimens of pediatric patients in Turkey. In this study, we also report the first clinical isolate of E. anophelis in Turkey. Since, the majority of strains were isolated from patients with CF; larger, prospective clinical studies are needed to establish whether chryseobacteria could be considered as an emerging opportunistic pathogen in patients with CF. [ABSTRACT FROM AUTHOR]

Published
2018
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27. COVID-19 associated multisystemic inflammatory syndrome in 614 children with and without overlap with Kawasaki disease-Turk MIS-C study group

Author

Dilek Yilmaz Ciftdogan, Yildiz Ekemen Keles, Benhur Sirvan Cetin, Nazan Dalgic Karabulut, Melike Emiroglu, Zafer Bagci, Ayse Buyukcam, Emine Hafize Erdeniz, Gul Arga, Edanur Yesil, Ozlem Cakici, Adem Karbuz, Zumrut Sahbudak Bal, Soner Sertan Kara, Arife Ozer, Ozge Metin Akcan, Sefika Elmas Bozdemir, Ayse Berna Anil, Hatice Uygun, Omer Kilic, Selda Hancerli Torun, Zuhal Umit, Murat Sutcu, Berfin Ozgokce Ozmen, Hatice Karaoglu Asrak, Gulsum Alkan, Ahu Kara Aksay, Cuneyt Ugur, Ahmet Ziya Birbilen, Burcu Bursal Duramaz, Esra Akyuz Ozkan, Ozgur Burakay, Sema Yildirim Arslan, Eda Karadag Oncel, Serkan Fazli Celik, Ahmet Osman Kilic, Seval Ozen, Remzi Sarikaya, Demet Demirkol, Gazi Arslan, Ozden Turel, Ahmet Sert, Ergul Sari, Zerrin Orbak, Irfan Oguz Sahin, Celal Varan, Hacer Akturk, Sadiye Kubra Tuter Oz, Fatih Durak, Mehmet Burhan Oflaz, Manolya Kara, Derya Karpuz, Mey Talip Petmezci, Nevin Hatipoglu, Selim Oncel, Mehmet Turgut, Ferhan Elmali, Ayper Somer, Necdet Kuyucu, Ener Cagri Dinleyici, Zafer Kurugöl, Ergin Ciftci, Ates Kara, BURSAL DURAMAZ, BURCU, TÜREL, ÖZDEN, Aktürk, Hacer, Çiftdoğan, Dilek Yılmaz, Keleş, Yıldız Ekemen, Çetin, Benhur Şirvan, Karabulut, Nazan Dalgıç, Emiroğlu, Melike, Bağcı, Zafer, Büyükçam, Ayşe, Erdeniz, Emine Hafize, Arga, Gül, Yeşil, Edanur, Çakıcı, Özlem, Karbuz, Adem, Bal, Zümrüt Şahbudak, Kara, Soner Sertan, Özer, Arife, Akcan, Özge Metin, Bozdemir, Şefika Elmas, Anıl, Ayşe Berna, Uygun, Hatice, Kılıç, Ömer, Torun, Selda Hancerli, Ümit, Zuhal, Sütcü, Murat, Özmen, Berfin ÖzgÖkce, Asrak, Hatice Karaoğlu, Alkan, Gülsüm, Aksay, Ahu Kara, Uğur, Cüneyt, Birbilen, Ahmet Ziya, Duramaz, Burcu Bursal, Özkan, Esra Akyüz, Burakay, Özgür, Arslan, Sema Yıldırım, Öncel, Eda Karadağ, Celik, Serkan Fazlı, Kılıç, Ahmet Osman, Özen, Seval, Sarıkaya, Remzi, Demirkol, Demet, Arslan, Gazi, Türel, Özden, Sert, Ahmet, Sarı, Ergül, Orbak, Zerrin, Şahin, İrfan Oğuz, Varan, Celal, Öz, Sadiye Kübra Tuter, Durak, Fatih, Oflaz, Mehmet Burhan, Kara, Manolya, Karpuz, Derya, Petmezci, Mey Talip, Hatipoğlu, Nevin, Öncel, Selim, Turgut, Mehmet, Elmalı, Ferhan, Somer, Ayper, Kuyucu, Necdet, Dinleyici, Ener Cağrı, Kurugöl, Zafer, Çiftci, Ergin, Kara, Ateş, Koç University Hospital, İstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Murat Sütçü / 0000-0002-2078-9796, Manolya Kara / 0000-0001-6234-7024, Sütçü, Murat, Murat Sütçü / AAR-5212-2020, Manolya Kara / AGI-2212-2022, Murat Sütçü / 55499199300, and Manolya Kara / 57213122996

Subjects
Lethargy, Kawasaki disease, SARS-CoV-2, COVID-19, MIS-C, Mucocutaneous Lymph Node Syndrome, Pediatrics, Systemic Inflammatory Response Syndrome, Children, Child, Preschool, Pediatrics, Perinatology and Child Health, Humans, Original Article, Child, Procalcitonin, Retrospective Studies
Abstract

Multisystemic inflammatory syndrome (MIS-C) diagnosis remains difficult because the clinical features overlap with Kawasaki disease (KD). The study aims to highlight the clinical and laboratory features and outcomes of patients with MISC whose clinical manifestations overlap with or without KD. This study is a retrospective analysis of a case series designed for patients aged 1 month to 18 years in 28 hospitals between November 1, 2020, and June 9, 2021. Patient demographics, complaints, laboratory results, echocardiographic results, system involvement, and outcomes were recorded. A total of 614 patients were enrolled; the median age was 7.4 years (interquartile range (IQR) 3.9-12 years). A total of 277 (45.1%) patients with MIS-C had manifestations that overlapped with KD, including 92 (33.3%) patients with complete KD and 185 (66.7%) with incomplete KD. Lymphocyte and platelet counts were significantly lower in patients with MISC, overlapped with KD (lymphocyte count 1080 vs. 1280 cells x mu L, p = 0.028; platelet count 166 vs. 216 cells x 10(3)/mu L, p < 0.001). The median serum procalcitonin levels were statistically higher in patients overlapped with KD (3.18 vs. 1.68 mu g/L, p = 0.001). Coronary artery dilatation was statistically significant in patients with overlap with KD (13.4% vs. 6.8%, p = 0.007), while myocarditis was significantly more common in patients without overlap with KD features (2.6% vs 7.4%, p = 0.009). The association between clinical and laboratory findings and overlap with KD was investigated. Age > 12 years reduced the risk of overlap with KD by 66% (p < 0.001, 95% CI 0.217-0.550), lethargy increased the risk of overlap with KD by 2.6-fold (p = 0.011, 95% CI 1.244-5.439), and each unit more albumin (g/dl) reduced the risk of overlap with KD by 60% (p < 0.001, 95% CI 0.298-0.559). Conclusion: Almost half of the patients with MISC had clinical features that overlapped with KD; in particular, incomplete KD was present. The median age was lower in patients with KD-like features. Lymphocyte and platelet counts were lower, and ferritin and procalcitonin levels were significantly higher in patients with overlap with KD., NA

Published
2022

28. Education of healthcare personnel working with pediatric patients during COVID-19 pandemic within the framework of infection control

Author

Aktürk, Hacer, Yenidoğan, İrem, Oygar, Pembe Derin, Büyükçam, Ayşe, Bal, Zümrüt Şahbudak, Dalgıç, Nazan, Bozdemir, Şefika Elmas, Karbuz, Adem, Çetin, Benhur Şirvan, Kara, Yalçın, Çetin, Ceren, Hatipoğlu, Nevin, Uygun, Hatice, Aygün, Fatma Deniz, Törün, Selda Hançerli, Okur, Dicle Şener, Çiftdoğan, Dilek Yılmaz, Kara, Tuğçe Tural, Yahşi, Aysun, Özer, Arife, Demir, Sevliya Öcal, Akkoç, Gülşen, Turan, Cansu, Salı, Enes, Şen, Semra, Erdeniz, Emine Hafize, Kara, Soner Sertan, Emiroğlu, Melike, Erat, Tuğba, Gürlevik, Sibel Laçinel, Sütçü, Murat, Aydin, Zeynep Gökçe Gayretli, Atıkan, Başak Yıldız, Yeşil, Edanur, Güner, Gizem, Çelebi, Emel, Efe, Kadir, İşançlı, Didem Kızmaz, Durmuş, Habibe Selver, Tekeli, Seher, Karaarslan, Ayşe, Bülbül, Lida, Almiş, Habip, Kaba, Özge, Keleş, Yıldız Ekemen, Yazıcıoğlu, Bahadır, Oğuz, Şerife Bahtiyar, Ovalı, Hüsnü Fahri, Doğan, Hazal Helin, Çelebi, Solmaz, Çakır, Deniz, Karasulu, Burcugül, Alkan, Gülsüm, Gül, Doruk, Küçükalioğlu, Burcu Parıltan, Avcu, Gülhadiye, Kukul, Musa Gürel, Bilen, Melis, Yaşar, Belma, Üstün, Tuğba, Kılıç, Ömer, Akın, Yasemin, Cebeci, Sinem Oral, Turgut, Mehmet, Yanartaş, Mehpare Sarı, Şahin, Aslıhan, Arslanoğlu, Sertaç, Elevli, Murat, Öz, Şadiye Kübra Tüter, Hatipoğlu, Halil, Erkum, İlyas Tolga, Demirbuğa, Asuman, Özçelik, Taha, Sarı, Emine Ergül, Akkuş, Gökhan, Hatipoğlu, Sadık Sami, Dinleyici, Ener Cağrı, Hacımustafaoğlu, Mustafa, Özkınay, Ferda, Kurugöl, Zafer, Cengiz, Ali Bülent, Somer, Ayper, Tezer, Hasan, Kara, Ateş, and Koç University Hospital

Subjects
Medicine, Pediatrics, COVID-19, Healthcare personnel, Personal protection, Education
Abstract

Objective: in the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic caused by SARS-CoV-2, proved to be no exception. Many healthcare workers died in the early stages of pandemic due to inadequate precautions and insufficient protection. It is essential to protect and maintain the safety of healthcare personnel for the confinement of pandemic as well as continuity of qualified healthcare services which is already under strain. Educating healthcare personnel on appropiate use of personal protective equipment (PPE) is as essential as procuring them. Material and methods: a survey is conducted on 4927 healthcare personnel working solely with pediatric patients from 32 different centers. Education given on PPE usage were questioned and analyzed depending on age, sex, occupation and region. Results: among four thousand nine hundred twelve healthcare personnel from 32 different centers 91% (n=4457) received education on PPE usage. Of those who received education only 36% was given both theoretical and applied education. Although there was no differences among different occupation groups, receiving education depended on regions. Conclusion: it is essential to educate healthcare personnel appropiately nationwidely for the continuity of qualified healthcare services during the pandemic. / Giriş: yeni ortaya çıkan patojenlerin neden olduğu salgınların erken dönemleri sağlık çalışanları için büyük bir risk taşımaktadır. SARS-CoV-2’nin neden olduğu pandemide de durum farklı olmamış, alınan yetersiz önlemler ve kişisel korunma eksikliği nedenleriyle pandemi başlangıcında birçok sağlık çalışanı hayatını kaybetmiştir. Sağlık çalışanlarının koruması ve güvenli ortamda çalışmalarının devamlılığının sağlanması sağlık hizmetlerinin aksamamasının yanında salgının sınırlandırması içinde gereklidir. Kişisel koruyucu ekipmaların kullanımı ile ilgili eğitimlerin verilmesi, gerekli durumlarda güncellenmesi koruyucu ekipmanların sağlanması kadar önemlidir. Gereç ve yöntemler: otuz iki farklı merkezde çocuklara sağlık hizmeti veren 4927 sağlık personeli üzerinde anket uygulanmış, kişisel koruyucu ekipman kullanımı konusunda alınan eğitim değerlendirilmiş, yaş, cinsiyet, meslek ve bölgesel farklılıkların eğitim alma üzerine etki edip etmediği değerlendirilmiştir. Bulgular: otuz iki farklı merkezden 4927 sağlık çalışanın katıldığı çalışmada, 4457 (%91) sağlık çalışanın kişisel koruyucu ekipmaların kullanımı ile ilgili eğitim aldığı saptanmış, yalnızca %36’sının hem teorik hem de uygulamalı eğitim aldığı bulunmuştur. Meslek grupları arasında eğitim alma yönünden fark görülmezken, bölgelere göre eğitim alıp almamada anlamlı fark olduğu saptanmıştır. Sonuç: tüm bölgelerde sağlık personelinin kişisel korunma konusunda eğitilmesi ve verilen eğitimin denetimi ve sürekliliği kaliteli sağlık hizmetlerinin devamlılığı için gereklidir., NA

Published
2020

29. Hand, foot, and mouth disease: could EPs® 7630 be a treatment option? A prospective randomized open-label multicenter clinical study.

Author

Sütçü M, Kara M, Yıldız F, Kılıç Ö, Tural Kara T, Akkoc G, Büyükçam A, Elmas Bozdemir Ş, Özgür Gündeşlioğlu Ö, Gül D, İseri Nepesov M, and Kara A

Abstract

Purpose: Hand, foot and mouth disease (HFMD) is a viral contagious disease of children caused by human enteroviruses (EVs) and coxsackieviruses (CVs). There is no specific treatment option for HFMD. EPs® 7630's anti-infective and immunomodulatory properties have previously been demonstrated in several in vitro and in vivo studies; however, the use of this herbal medicine in children with HFMD has not previously been investigated., Methods: This prospective randomized multicenter clinical study included 208 children with HFMD. The diagnosis was made by pediatricians. The patients who were within the first 48 h of symptom onset (according to the first onset of fever and skin findings) were enrolled. The study participants were assigned into 2 groups as EPs® 7630 and control groups. All patients were followed up twice more, 48 h after the first admission and on the 5th-7th day. Another phone evaluation was conducted for those with continued complaints from the previous visit., Results: The median age was 27 (12-112) months. The male-female ratio was 0.98. One hundred thirty one (63%) of 190 patients had no history of household contact. EPs® 7630 group included 94 and control group included 96 patients. A significant difference was found between the groups in terms of complaint scores at the visits made at the 48th h of the treatment and on days 5-7 ( p  < 0.001). The mean ± SD disease duration of EPs® 7630 users was significantly shorter 6.07 ± 0.70 days (95% CI: 5.92-6.21)] than the control group [8.58 ± 0.94 days (95% CI: 8.39-8.77)] ( p  < 0.001). Besides, the hospitalization rate among the EPs® 7630 users were significantly lower ( p  = 0.019). No side effects were observed, except for unpleasant taste, which was reported in 5 patients (EPs® 7630 group)., Conclusion: Considering its efficacy and safety profile EPs® 7630 may represent a feasible herbal-based treatment option for children with HFMD., Clinical Trial Registration: ClinicalTrials.gov, identifier (NCT06353477)., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2024 Sütçü, Kara, Yıldız, Kılıç, Tural Kara, Akkoc, Büyükçam, Elmas Bozdemir, Özgür Gündeşlioğlu, Gül, İseri Nepesov and Kara.)

Published
2024
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