Search

Your search keyword '"Aziz-Sultan, Mohammad A"' showing total 343 results
Start Over Author "Aziz-Sultan, Mohammad A"
343 results on '"Aziz-Sultan, Mohammad A"'

1. Outcomes of mechanical thrombectomy in anticoagulated patients with acute distal and medium vessel stroke.

Author

Salim, Hamza, Musmar, Basel, Adeeb, Nimer, Yedavalli, Vivek, Lakhani, Dhairya, Grewal, Sahibjot, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri, Kühn, Anna, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Tan, Benjamin, Regenhardt, Robert, Heit, Jeremy, Cancelliere, Nicole, Bernstock, Joshua, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João, Harker, Pablo, Radu, Răzvan, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James, Nguyen, Thanh, Varela, Ricardo, Baker, Amanda, Essibayi, Muhammed, Altschul, David, Gonzalez, Nestor, Möhlenbruch, Markus, Costalat, Vincent, Gory, Benjamin, Stracke, Christian, Aziz-Sultan, Mohammad, Hecker, Constantin, Shaikh, Hamza, Liebeskind, David, Pedicelli, Alessandro, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman, Pereira, Vitor, Guenego, Adrien, and Dmytriw, Adam

Subjects
Stroke, anticoagulation, thrombectomy, Humans, Aged, Male, Female, Anticoagulants, Retrospective Studies, Ischemic Stroke, Aged, 80 and over, Thrombectomy, Treatment Outcome, Middle Aged, Stroke
Abstract

BACKGROUND: Stroke remains a major health concern globally, with oral anticoagulants widely prescribed for stroke prevention. The efficacy and safety of mechanical thrombectomy (MT) in anticoagulated patients with distal medium vessel occlusions (DMVO) are not well understood. METHODS: This retrospective analysis involved 1282 acute ischemic stroke (AIS) patients who underwent MT in 37 centers across North America, Asia, and Europe from September 2017 to July 2023. Data on demographics, clinical presentation, treatment specifics, and outcomes were collected. The primary outcomes were functional outcomes at 90 days post-MT, measured by modified Rankin Scale (mRS) scores. Secondary outcomes included reperfusion rates, mortality, and hemorrhagic complications. RESULTS: Of the patients, 223 (34%) were on anticoagulation therapy. Anticoagulated patients were older (median age 78 vs 74 years; p

Published
2024

2. Endovascular therapy versus medical management in isolated posterior cerebral artery acute ischemic stroke: A multinational multicenter propensity score-weighted study.

Author

Salim, Hamza, Pulli, Benjamin, Yedavalli, Vivek, Musmar, Basel, Adeeb, Nimer, Lakhani, Dhairya, Essibayi, Muhammed, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri, Kühn, Anna, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Grewal, Inayat, Tan, Benjamin, Regenhardt, Robert, Heit, Jeremy, Cancelliere, Nicole, Bernstock, Joshua, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João, Harker, Pablo, Radu, Răzvan, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James, Nguyen, Thanh, Varela, Ricardo, Baker, Amanda, Altschul, David, Gonzalez, Nestor, Möhlenbruch, Markus, Costalat, Vincent, Gory, Benjamin, Stracke, Christian, Aziz-Sultan, Mohammad, Hecker, Constantin, Shaikh, Hamza, Griessenauer, Christoph, Liebeskind, David, Pedicelli, Alessandro, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman, Pereira, Vitor, Wintermark, Max, Guenego, Adrien, and Dmytriw, Adam

Subjects
Acute ischemic stroke, endovascular therapy, medical management, posterior cerebral artery, propensity score analysis
Abstract

BACKGROUND: Despite the proven effectiveness of endovascular therapy (EVT) in acute ischemic strokes (AIS) involving anterior circulation large vessel occlusions, isolated posterior cerebral artery (PCA) occlusions (iPCAo) remain underexplored in clinical trials. This study investigates the comparative effectiveness and safety of EVT against medical management (MM) in patients with iPCAo. METHODS: This multinational, multicenter propensity score-weighted study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, involving 37 centers across North America, Asia, and Europe. We included iPCAo patients treated with either EVT or MM. The primary outcome was the modified Rankin Scale (mRS) at 90 days, with secondary outcomes including functional independence, mortality, and safety profiles such as hemorrhagic complications. RESULTS: A total of 177 patients were analyzed (88 MM and 89 EVT). EVT showed a statistically significant improvement in 90-day mRS scores (OR = 0.55, 95% CI = 0.30-1.00, p = 0.048), functional independence (OR = 2.52, 95% CI = 1.02-6.20, p = 0.045), and a reduction in 90-day mortality (OR = 0.12, 95% CI = 0.03-0.54, p = 0.006) compared to MM. Hemorrhagic complications were not significantly different between the groups. CONCLUSION: EVT for iPCAo is associated with better neurological outcomes and lower mortality compared to MM, without an increased risk of hemorrhagic complications. Nevertheless, these results should be interpreted with caution due to the studys observational design. The findings are hypothesis-generating and highlight the need for future randomized controlled trials to confirm these observations and establish definitive treatment guidelines for this patient population.

Published
2024

3. Predictive value of follow-up infarct volume on functional outcomes in middle cerebral artery M2 segment vessel occlusion stroke treated with mechanical thrombectomy.

Author

Yedavalli, Vivek, Salim, Hamza, Musmar, Basel, Adeeb, Nimer, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri, Kühn, Anna, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Tan, Benjamin, Regenhardt, Robert, Heit, Jeremy, Cancelliere, Nicole, Bernstock, Joshua, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João, Harker, Pablo, Radu, Răzvan, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James, Nguyen, Thanh, Varela, Ricardo, Baker, Amanda, Essibayi, Muhammed, Altschul, David, Gonzalez, Nestor, Möhlenbruch, Markus, Costalat, Vincent, Gory, Benjamin, Stracke, Christian, Aziz-Sultan, Mohammad, Hecker, Constantin, Shaikh, Hamza, Liebeskind, David, Pedicelli, Alessandro, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman, Pereira, Vitor, Guenego, Adrien, and Dmytriw, Adam

Subjects
Stroke, follow-up infarct volume, mechanical thrombectomy, medium vessel occlusion
Abstract

BACKGROUND: Medium vessel occlusion (MeVO) strokes, particularly affecting the M2 segment of the middle cerebral artery, represent a critical proportion of acute ischemic strokes, posing significant challenges in management and outcome prediction. The efficacy of mechanical thrombectomy (MT) in MeVO stroke may warrant reliable predictors of functional outcomes. This study aimed to investigate the prognostic value of follow-up infarct volume (FIV) for predicting 90-day functional outcomes in MeVO stroke patients undergoing MT. METHODS: This multicenter, retrospective cohort study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, covering patients with acute ischemic stroke due to M2 segment occlusion treated with MT. We examined the relationship between 90-day functional outcomes, measured by the modified Rankin Scale (mRS), and follow-up infarct volume (FIV), assessed through CT or MRI within 12-36 h post-MT. RESULTS: Among 130 participants, specific FIV thresholds were identified with high specificity and sensitivity for predicting outcomes. A FIV ⩽5 ml was highly specific for predicting favorable and excellent outcomes. The optimal cut-off for both prognostications was identified at ⩽15 ml by the Youden Index, with significant reductions in the likelihood of favorable outcomes observed above a 40 ml threshold. Receiver Operator Curve (ROC) analyses confirmed FIV as a superior predictor of functional outcomes compared to traditional recanalization scores, such as final modified thrombolysis in cerebral infarction score (mTICI). Multivariable analysis further highlighted the inverse relationship between FIV and positive functional outcomes. CONCLUSIONS: FIV within 36 h post-MT serves as a potent predictor of 90-day functional outcomes in patients with M2 segment MeVO strokes. Establishing FIV thresholds may aid in the prognostication of stroke outcomes, suggesting a role for FIV in guiding post intervention treatment decisions and informing clinical practice. Future research should focus on validating these findings across diverse patient populations and exploring the integration of FIV measurements with other clinical and imaging markers to enhance outcome prediction accuracy.

Published
2024

4. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Author

Dmytriw, Adam A., Salim, Hamza, Musmar, Basel, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent M., Ibrahim, Mohamed K., Mohammed, Marwa A., Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer E., Ogilvie, Mark, Sporns, Peter, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Altschul, David, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M., Pereira, Vitor Mendes, Patel, Aman B., and Adeeb, Nimer

Published
2024
Full Text
View/download PDF

5. Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study

Author

El Naamani, Kareem, Mastorakos, Panagiotis, Adeeb, Nimer, Lan, Mathews, Castiglione, James, Khanna, Omaditya, Diestro, Jose Danilo Bengzon, McLellan, Rachel M., Dibas, Mahmoud, Vranic, Justin E., Aslan, Assala, Cuellar-Saenz, Hugo H., Guenego, Adrien, Carnevale, Joseph, Saliou, Guillaume, Ulfert, Christian, Möhlenbruch, Markus, Foreman, Paul M., Vachhani, Jay A., Hafeez, Muhammad U., Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Michelozzi, Caterina, Spears, Julian, Panni, Pietro, Griessenauer, Christoph J., Asadi, Hamed, Regenhardt, Robert W., Stapleton, Christopher J., Ghozy, Sherief, Siddiqui, Adnan, Patel, Nirav J., Kan, Peter, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Zanaty, Mario, Ghosh, Ritam, Abbas, Rawad, Amllay, Abdelaziz, Tjoumakaris, Stavropoula I., Gooch, Michael R., Cancelliere, Nicole M., Herial, Nabeel A., Rosenwasser, Robert H., Zarzour, Hekmat, Schmidt, Richard F., Pereira, Vitor Mendes, Patel, Aman B., Jabbour, Pascal, and Dmytriw, Adam A.

Published
2024
Full Text
View/download PDF

6. Somatic Variants in SVIL in Cerebral Aneurysms

Author

Lai, Pui Man Rosalind, Ryu, Jee-Yeon, Park, Sang-Cheol, Gross, Bradley A, Dickinson, Lawrence D, Dagen, Sarajune, Aziz-Sultan, Mohammad Ali, Boulos, Alan S, Barrow, Daniel L, Batjer, H Hunt, Blackburn, Spiros, Chang, Edward F, Chen, P Roc, Colby, Geoffrey P, Cosgrove, Garth Rees, David, Carlos A, Day, Arthur L, Frerichs, Kai U, Niemela, Mika, Ojemann, Steven G, Patel, Nirav J, Shi, Xiangen, Valle-Giler, Edison P, Wang, Anthony C, Welch, Babu G, Zusman, Edie E, Weiss, Scott T, and Du, Rose

Subjects
Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Brain Disorders, Biotechnology, Cardiovascular, Stroke, Neurosciences, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Clinical sciences
Abstract

Background and objectivesWhile somatic mutations have been well-studied in cancer, their roles in other complex traits are much less understood. Our goal is to identify somatic variants that may contribute to the formation of saccular cerebral aneurysms.MethodsWe performed whole-exome sequencing on aneurysm tissues and paired peripheral blood. RNA sequencing and the CRISPR/Cas9 system were then used to perform functional validation of our results.ResultsSomatic variants involved in supervillin (SVIL) or its regulation were found in 17% of aneurysm tissues. In the presence of a mutation in the SVIL gene, the expression level of SVIL was downregulated in the aneurysm tissue compared with normal control vessels. Downstream signaling pathways that were induced by knockdown of SVIL via the CRISPR/Cas9 system in vascular smooth muscle cells (vSMCs) were determined by evaluating changes in gene expression and protein kinase phosphorylation. We found that SVIL regulated the phenotypic modulation of vSMCs to the synthetic phenotype via Krüppel-like factor 4 and platelet-derived growth factor and affected cell migration of vSMCs via the RhoA/ROCK pathway.DiscussionWe propose that somatic variants form a novel mechanism for the development of cerebral aneurysms. Specifically, somatic variants in SVIL result in the phenotypic modulation of vSMCs, which increases the susceptibility to aneurysm formation. This finding suggests a new avenue for the therapeutic intervention and prevention of cerebral aneurysms.

Published
2022

7. Off-Label use of Woven EndoBridge device for intracranial brain aneurysm treatment: Modeling of occlusion outcome

Author

Dibas, Mahmoud, Spears, Julian, Sundararajan, Sri Hari, Al Balush, Ali, Vranic, Justin E., Inoue, Yasuaki, Mirshahi, Shervin, Alotaibi, Naif M., Harker, Pablo, Tutino, Vincent M., Sporns, Peter, Brehm, Alex, Essibayi, Muhammed Amir, Jabal, Mohamed Sobhi, Musmar, Basel, Adeeb, Nimer, Salim, Hamza, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M, Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Yavuz, Kivilcim, Gunes, Yasin Celal, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Starke, Robert M., Hassan, Ameer, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Gutierrez, Juan Carlos Martinez, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Haranhalli, Neil, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M, Pereira, Vitor Mendes, Patel, Aman B., Altschul, David, and Dmytriw, Adam A.

Published
2024
Full Text
View/download PDF

8. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Knopman, Jared, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
Full Text
View/download PDF

9. Acute ischaemic stroke associated with SARS-CoV-2 infection in North America

Author

Dmytriw, Adam A, Dibas, Mahmoud, Phan, Kevin, Efendizade, Aslan, Johanna, Ospel, Schirmer, Clemens, Settecase, Fabio, Heran, Manraj KS, Kühn, Anna Luisa, Puri, Ajit S, Menon, Bijoy K, Sivakumar, Sanjeev, Mowla, Askan, Vela-Duarte, Daniel, Linfante, Italo, Dabus, Guilherme C, Regenhardt, Robert W, D'Amato, Salvatore, Rosenthal, Joseph A, Zha, Alicia, Talukder, Nafee, Sheth, Sunil A, Hassan, Ameer E, Cooke, Daniel L, Leung, Lester Y, Malek, Adel M, Voetsch, Barbara, Sehgal, Siddharth, Wakhloo, Ajay K, Goyal, Mayank, Wu, Hannah, Cohen, Jake, Ghozy, Sherief, Turkel-Parella, David, Farooq, Zerwa, Vranic, Justin, Rabinov, James D, Stapleton, Christopher J, Minhas, Ramandeep, Velayudhan, Vinodkumar, Chaudhry, Zeshan Ahmed, Xavier, Andrew, Bullrich, Maria Bres, Pandey, Sachin, Sposato, Luciano A, Johnson, Stephen A, Gupta, Gaurav, Khandelwal, Priyank, Ali, Latisha, Liebeskind, David S, Farooqui, Mudassir, Ortega-Gutierrez, Santiago, Nahab, Fadi, Jillella, Dinesh V, Chen, Karen, Aziz-Sultan, Mohammad Ali, Abdalkader, Mohamad, Kaliaev, Artem, Nguyen, Thanh N, Haussen, Diogo C, Nogueira, Raul G, Haq, Israr Ul, Zaidat, Osama O, Sanborn, Emma, Leslie-Mazwi, Thabele M, Patel, Aman B, Siegler, James E, and Tiwari, Ambooj

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Stroke, Clinical Research, Neurosciences, Good Health and Well Being, Brain Ischemia, COVID-19, Humans, Ischemic Stroke, Middle Aged, Retrospective Studies, SARS-CoV-2, Thrombectomy, Treatment Outcome, stroke, interventional, North American Neurovascular COVID-19 (NAN-C) Consortium & Society of Vascular and Interventional Neurology (SVIN) Investigators, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, Clinical sciences
Abstract

BackgroundTo analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome.MethodsMulticentre retrospective cohort study of COVID-19 patients with AIS who presented to 30 stroke centres in the USA and Canada between 14 March and 30 August 2020. The primary endpoint was poor functional outcome, defined as a modified Rankin Scale (mRS) of 5 or 6 at discharge. Secondary endpoints include favourable outcome (mRS ≤2) and mortality at discharge, ordinal mRS (shift analysis), symptomatic intracranial haemorrhage (sICH) and occurrence of in-hospital complications.ResultsA total of 216 COVID-19 patients with AIS were included. 68.1% (147/216) were older than 60 years, while 31.9% (69/216) were younger. Median [IQR] National Institutes of Health Stroke Scale (NIHSS) at presentation was 12.5 (15.8), and 44.2% (87/197) presented with large vessel occlusion (LVO). Approximately 51.3% (98/191) of the patients had poor outcomes with an observed mortality rate of 39.1% (81/207). Age >60 years (aOR: 5.11, 95% CI 2.08 to 12.56, p

Published
2022

10. Correction to: The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Jared Knopman, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
Full Text
View/download PDF

12. Improved Generalizability in Medical Computer Vision: Hyperbolic Deep Learning in Multi-Modality Neuroimaging.

Author

Ayubcha, Cyrus, Sajed, Sulaiman, Omara, Chady, Veldman, Anna B., Singh, Shashi B., Lokesha, Yashas Ullas, Liu, Alex, Aziz-Sultan, Mohammad Ali, Smith, Timothy R., and Beam, Andrew

Subjects
COMPUTER-assisted image analysis (Medicine), CONVOLUTIONAL neural networks, COMPUTER vision, HYPERBOLOID structures, ALZHEIMER'S disease, DEEP learning
Abstract

Deep learning has shown significant value in automating radiological diagnostics but can be limited by a lack of generalizability to external datasets. Leveraging the geometric principles of non-Euclidean space, certain geometric deep learning approaches may offer an alternative means of improving model generalizability. This study investigates the potential advantages of hyperbolic convolutional neural networks (HCNNs) over traditional convolutional neural networks (CNNs) in neuroimaging tasks. We conducted a comparative analysis of HCNNs and CNNs across various medical imaging modalities and diseases, with a focus on a compiled multi-modality neuroimaging dataset. The models were assessed for their performance parity, robustness to adversarial attacks, semantic organization of embedding spaces, and generalizability. Zero-shot evaluations were also performed with ischemic stroke non-contrast CT images. HCNNs matched CNNs' performance in less complex settings and demonstrated superior semantic organization and robustness to adversarial attacks. While HCNNs equaled CNNs in out-of-sample datasets identifying Alzheimer's disease, in zero-shot evaluations, HCNNs outperformed CNNs and radiologists. HCNNs deliver enhanced robustness and organization in neuroimaging data. This likely underlies why, while HCNNs perform similarly to CNNs with respect to in-sample tasks, they confer improved generalizability. Nevertheless, HCNNs encounter efficiency and performance challenges with larger, complex datasets. These limitations underline the need for further optimization of HCNN architectures. HCNNs present promising improvements in generalizability and resilience for medical imaging applications, particularly in neuroimaging. Despite facing challenges with larger datasets, HCNNs enhance performance under adversarial conditions and offer better semantic organization, suggesting valuable potential in generalizable deep learning models in medical imaging and neuroimaging diagnostics. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

14. The impact of postoperative aspirin in patients undergoing Woven EndoBridge: a multicenter, institutional, propensity score-matched analysis

Author

Dmytriw, Adam A, Musmar, Basel, Salim, Hamza, Aslan, Assala, Cancelliere, Nicole M, McLellan, Rachel M, Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V, Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph Anthony, Saliou, Guillaume, Mastorakos, Panagiotis, El Naamani, Kareem, Shotar, Eimad, Premat, Kevin, Mo¨hlenbruch, Markus A, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M, Lylyk, Ivan, Foreman, Paul M, Vachhani, Jay A, Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad Ubaid, Catapano, Joshua S, Waqas, Muhammad, Tutino, Vincent M, Ibrahim, Mohamed K, Mohammed, Marwa A, Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D, Ren, Yifan, Schirmer, Clemens M, Piano, Mariangela, Kuhn, Anna Luisa, Michelozzi, Caterina, Elens, Stephanie, Hasan, Zuha, Starke, Robert M, Hassan, Ameer E, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie Teresa, Psychogios, Marios-Nikos, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan Karl, Huynh, Thien J, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A, Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S, Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberpfalzer, Monika, Griessenauer, Christoph J, Asadi, Hamed, Siddiqui, Adnan H, Brook, Allan L, Altschul, David, Ducruet, Andrew F, Albuquerque, Felipe C, Regenhardt, Robert W, Stapleton, Christopher J, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth Reddy, Knopman, Jared, Aziz-Sultan, Mohammad A, Tjoumakaris, Stavropoula I, Clarencon, Frédéric, Limbucci, Nicola, Cuellar, Hugo H, Jabbour, Pascal M, Pereira, Vitor M, Patel, Aman B, and Adeeb, Nimer

Abstract

BackgroundThe Woven EndoBridge (WEB) device is frequently used for the treatment of intracranial aneurysms. Postoperative management, including the use of aspirin, varies among clinicians and institutions, but its impact on the outcomes of the WEB has not been thoroughly investigated.MethodsThis was a retrospective, multicenter study involving 30 academic institutions in North America, South America, and Europe. Data from 1492 patients treated with the WEB device were included. Patients were categorized into two groups based on their postoperative use of aspirin (aspirin group: n=1124, non-aspirin group: n=368). Data points included patient demographics, aneurysm characteristics, procedural details, complications, and angiographic and functional outcomes. Propensity score matching (PSM) was applied to balance variables between the two groups.ResultsPrior to PSM, the aspirin group exhibited significantly higher rates of modified Rankin scale (mRS) mRS 0–1 and mRS 0–2 (89.8% vs 73.4% and 94.1% vs 79.8%, p<0.001), lower rates of mortality (1.6% vs 8.6%, p<0.001), and higher major compaction rates (13.4% vs 7%, p<0.001). Post-PSM, the aspirin group showed significantly higher rates of retreatment (p=0.026) and major compaction (p=0.037) while maintaining its higher rates of good functional outcomes and lower mortality rates. In the multivariable regression, aspirin was associated with higher rates of mRS 0–1 (OR 2.166; 95% CI 1.16 to 4, p=0.016) and mRS 0–2 (OR 2.817; 95% CI 1.36 to 5.88, p=0.005) and lower rates of mortality (OR 0.228; 95% CI 0.06 to 0.83, p=0.025). However, it was associated with higher rates of retreatment (OR 2.471; 95% CI 1.11 to 5.51, p=0.027).ConclusionsAspirin use post-WEB treatment may lead to better functional outcomes and lower mortality but with higher retreatment rates. These insights are crucial for postoperative management after WEB procedures, but further studies are necessary for validation.

Published
2025
Full Text
View/download PDF

15. Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke)

Author

Froehler, Michael T, Saver, Jeffrey L, Zaidat, Osama O, Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P, Haussen, Diogo C, Hellinger, Frank R, Yavagal, Dileep R, Yao, Tom L, Liebeskind, David S, Jadhav, Ashutosh P, Gupta, Rishi, Hassan, Ameer E, Martin, Coleman O, Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G, Gandhi, Ravi H, Peterson, Eric C, Dashti, Shervin R, Given, Curtis A, Mehta, Brijesh P, Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H, Kvamme, Peter, Grobelny, Thomas J, Hussain, Muhammad S, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J, Ecker, Robert D, Schirmer, Clemens M, Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P, Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H, Dumont, Travis M, Alhajeri, Abdulnasser, Taqi, M Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S, Chitale, Rohan, Deshaies, Eric M, Robinson, David H, Kallmes, David F, Baxter, Blaise W, Jumaa, Mouhammad A, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D, Suzuki, Shuichi, Fessler, Richard D, Almandoz, Josser E Delgado, Martin, Jerry C, and Mueller-Kronast, Nils H

Subjects
Stroke, Clinical Research, Brain Disorders, Endovascular Procedures, Hospitals, Humans, Ischemia, Patient Transfer, Prospective Studies, Registries, Survival Analysis, Thrombectomy, Time Factors, Treatment Outcome, emergency medical services, endovascular treatment, ischemic stroke, stent retriever, systems of care, STRATIS Investigators, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Abstract

BackgroundEndovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.MethodsSTRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or without intravenous tissue plasminogen activator and were admitted to endovascular-capable centers via either interhospital transfer or direct presentation. The primary clinical outcome was functional independence (modified Rankin Score 0-2) at 90 days. We assessed (1) real-world time metrics of stroke care delivery, (2) outcome differences between direct and transfer patients undergoing MT, and (3) the potential impact of local hospital bypass.ResultsA total of 984 patients were analyzed. Median onset-to-revascularization time was 202.0 minutes for direct versus 311.5 minutes for transfer patients (P

Published
2017

18. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Diestro, Jose Danilo Bengzon, Dibas, Mahmoud, Phan, Kevin, Sweid, Ahmad, Cuellar-Saenz, Hugo H., Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Sundararajan, Sri Hari, Carnevale, Joseph, Saliou, Guillaume, Möhlenbruch, Markus, Vranic, Justin E., Rabinov, James D., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Abbas, Rawad, Inoue, Yasuaki, Capirossi, Carolina, Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna Luisa, Michelozzi, Caterina, Elens, Stéphanie, Regenhardt, Robert W., Ghozy, Sherief, Alotaibi, Naif M., Tjoumakaris, Stavropoula, Starke, Robert M., Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Brooks, Mark, Maingard, Julian, Jhamb, Ashu, Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Savardekar, Amey, Boddu, Srikanth, Knopman, Jared, Limbucci, Nicola, Chen, Karen S., Aziz-Sultan, Mohammad A., Stapleton, Christopher J., Jabbour, Pascal, Cognard, Christophe, Patel, Aman B., and Adeeb, Nimer

Published
2021
Full Text
View/download PDF

20. Treatment of Large Intracranial Aneurysms Using the Woven EndoBridge (WEB): A Propensity Score-Matched Analysis

Author

Musmar, Basel, Salim, Hamza, Adeeb, Nimer, Aslan, Assala, Aljeradat, Bahaa, Diestro, Jose, McLellan, Rachel, Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann, Guenego, Adrien, Renieri, Leonardo, Cancelliere, Nicole, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, El Naamani, Kareem, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Vranic, Justin, Chung, Charlotte, Salem, Mohamed, Lylyk, Ivan, Foreman, Paul, Vachhani, Jay, Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad, Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent, Ibrahim, Mohamed, Mohammed, Marwa, Ozates, M. Ozgur, Ayberk, Giyas, Rabinov, James, Ren, Yifan, Schirmer, Clemens, Piano, Mariangela, Kühn, Anna, Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert, Hassan, Ameer, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie, Psychogios, Marios, Ulfert, Christian, Spears, Julian, Jankowitz, Brian, Burkhardt, Jan-Karl, Domingo, Ricardo, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed, Sheth, Sunil, Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit, Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph, Asadi, Hamed, Siddiqui, Adnan, Brook, Allan, Altschul, David, Ducruet, Andrew, Albuquerque, Felipe, Regenhardt, Robert, Stapleton, Christopher, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A, Tjoumakaris, Stavropoula, Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo, Jabbour, Pascal, Pereira, Vitor, Patel, Aman, Dmytriw, Adam, Musmar, Basel, Salim, Hamza, Adeeb, Nimer, Aslan, Assala, Aljeradat, Bahaa, Diestro, Jose, McLellan, Rachel, Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann, Guenego, Adrien, Renieri, Leonardo, Cancelliere, Nicole, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, El Naamani, Kareem, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Vranic, Justin, Chung, Charlotte, Salem, Mohamed, Lylyk, Ivan, Foreman, Paul, Vachhani, Jay, Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad, Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent, Ibrahim, Mohamed, Mohammed, Marwa, Ozates, M. Ozgur, Ayberk, Giyas, Rabinov, James, Ren, Yifan, Schirmer, Clemens, Piano, Mariangela, Kühn, Anna, Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert, Hassan, Ameer, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie, Psychogios, Marios, Ulfert, Christian, Spears, Julian, Jankowitz, Brian, Burkhardt, Jan-Karl, Domingo, Ricardo, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed, Sheth, Sunil, Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit, Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph, Asadi, Hamed, Siddiqui, Adnan, Brook, Allan, Altschul, David, Ducruet, Andrew, Albuquerque, Felipe, Regenhardt, Robert, Stapleton, Christopher, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A, Tjoumakaris, Stavropoula, Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo, Jabbour, Pascal, Pereira, Vitor, Patel, Aman, and Dmytriw, Adam

Abstract

The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.

Published
2024

23. The impact of postoperative aspirin in patients undergoing Woven EndoBridge: a multicenter, institutional, propensity score-matched analysis

Author

Dmytriw, Adam A, primary, Musmar, Basel, additional, Salim, Hamza, additional, Aslan, Assala, additional, Cancelliere, Nicole M, additional, McLellan, Rachel M, additional, Algin, Oktay, additional, Ghozy, Sherief, additional, Dibas, Mahmoud, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Carnevale, Joseph Anthony, additional, Saliou, Guillaume, additional, Mastorakos, Panagiotis, additional, El Naamani, Kareem, additional, Shotar, Eimad, additional, Premat, Kevin, additional, Möhlenbruch, Markus A, additional, Kral, Michael, additional, Doron, Omer, additional, Chung, Charlotte, additional, Salem, Mohamed M, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Shaikh, Hamza, additional, Župančić, Vedran, additional, Hafeez, Muhammad Ubaid, additional, Catapano, Joshua S, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Ibrahim, Mohamed K, additional, Mohammed, Marwa A, additional, Imamoglu, Cetin, additional, Bayrak, Ahmet, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Hasan, Zuha, additional, Starke, Robert M, additional, Hassan, Ameer E, additional, Ogilvie, Mark, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Brinjikji, Waleed, additional, Nawka, Marie Teresa, additional, Psychogios, Marios-Nikos, additional, Ulfert, Christian, additional, Diestro, Jose Danilo Bengzon, additional, Pukenas, Bryan, additional, Burkhardt, Jan Karl, additional, Huynh, Thien J, additional, Martinez-Gutierrez, Juan Carlos, additional, Essibayi, Muhammed Amir, additional, Sheth, Sunil A, additional, Spiegel, Gary, additional, Tawk, Rabih, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Nossek, Erez, additional, Raz, Eytan, additional, Killer-Oberpfalzer, Monika, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan H, additional, Brook, Allan L, additional, Altschul, David, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Regenhardt, Robert W, additional, Stapleton, Christopher J, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Tjoumakaris, Stavropoula I, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Cuellar, Hugo H, additional, Jabbour, Pascal M, additional, Pereira, Vitor M, additional, Patel, Aman B, additional, and Adeeb, Nimer, additional

Published
2024
Full Text
View/download PDF

26. Endovascular Applications for the Management of High-Grade Gliomas in the Modern Era.

Author

Kappel, Ari D., Jha, Rohan, Guggilapu, Saibaba, Smith, William J., Feroze, Abdullah H., Dmytriw, Adam A., Vicenty-Padilla, Juan, Alcedo Guardia, Rodolfo E., Gessler, Florian A., Patel, Nirav J., Du, Rose, See, Alfred P., Peruzzi, Pier Paolo, Aziz-Sultan, Mohammad A., and Bernstock, Joshua D.

Subjects
GLIOMA treatment, PATIENT safety, BLOOD-brain barrier, ENDOVASCULAR surgery, TUMOR grading, MINIMALLY invasive procedures, DRUG delivery systems, ULTRASONIC imaging, CANCER chemotherapy
Abstract

Simple Summary: This review discusses new treatments for high-grade gliomas (HGGs), aggressive brain tumors that are difficult to treat. It focuses on emerging endovascular therapies and future directions. Endovascular methods use catheters in a minimally invasive manner to deliver drugs to the tumor through blood vessels in the brain while limiting harm to the rest of the body. Super-selective intra-arterial cerebral infusion (SSIACI) is an endovascular technique that aims to deliver treatments directly to the tumor by reaching the closest blood vessels supplying the tumor. Many challenges remain to fully adopting these techniques in clinical practice, including the ability of drugs to cross the blood–brain barrier, and getting the drugs to stay in the tumor for long enough before they are washed out by normal blood in the brain. Focused ultrasound and hyperosmotic disruption are techniques which might help with these challenges. Researchers are investigating new drugs beyond traditional chemotherapies, such as radiation embedded molecules and immune-based therapies. Future directions include monitoring tumors with endovascular sampling; changing drug formulations to stay in the tumor longer; and investigating other treatments, like radioembolization. These endovascular strategies have the potential to improve how HGGs are treated, but more research is needed to ensure they work well and are safe for patients. High-grade gliomas (HGGs) have a poor prognosis and are difficult to treat. This review examines the evolving landscape of endovascular therapies for HGGs. Recent advances in endovascular catheter technology and delivery methods allow for super-selective intra-arterial cerebral infusion (SSIACI) with increasing precision. This treatment modality may offer the ability to deliver anti-tumoral therapies directly to tumor regions while minimizing systemic toxicity. However, challenges persist, including blood–brain barrier (BBB) penetration, hemodynamic complexities, and drug–tumor residence time. Innovative adjunct techniques, such as focused ultrasound (FUS) and hyperosmotic disruption, may facilitate BBB disruption and enhance drug penetration. However, hemodynamic factors that limit drug residence time remain a limitation. Expanding therapeutic options beyond chemotherapy, including radiotherapy and immunobiologics, may motivate future investigations. While preclinical and clinical studies demonstrate moderate efficacy, larger randomized trials are needed to validate the clinical benefits. Additionally, future directions may involve endovascular sampling for peri-tumoral surveillance; changes in drug formulations to prolong residence time; and the exploration of non-pharmaceutical therapies, like radioembolization and photodynamic therapy. Endovascular strategies hold immense potential in reshaping HGG treatment paradigms, offering targeted and minimally invasive approaches. However, overcoming technical challenges and validating clinical efficacy remain paramount for translating these advancements into clinical care. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

27. Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT)

Author

Fiorella, David, primary, Molyneux, Andy, additional, Coon, Alex, additional, Szikora, Istvan, additional, Saatci, Isil, additional, Baltacioglu, Feyyaz, additional, Aziz-Sultan, Mohammad A, additional, Hoit, Daniel, additional, Delgado Almandoz, Josser E, additional, Elijovich, Lucas, additional, Cekirge, H Saruhan, additional, Byrne, James, additional, Klisch, Joachim, additional, and Arthur, Adam S, additional

Published
2023
Full Text
View/download PDF

29. Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry

Author

Zaidat, Osama O., Mueller-Kronast, Nils H., Hassan, Ameer E., Haussen, Diogo C., Jadhav, Ashutosh P., Froehler, Michael T., Jahan, Reza, Ali Aziz-Sultan, Mohammad, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Gupta, Rishi, Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin, Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad Shazam, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Chebl, Alex Bou, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, Muhammad A., Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David, Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammed, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado-Almandoz, Josser, Martin, Jerry C., and Liebeskind, David S.

Published
2019
Full Text
View/download PDF

36. Transradial versus transfemoral access for embolization of intracranial aneurysms with the Woven EndoBridge device: a propensity score–matched study

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Assala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
Full Text
View/download PDF

37. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., primary, Dibas, Mahmoud, additional, Ghozy, Sherief, additional, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Phan, Kevin, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Tjoumakaris, Stavropoula, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, and Patel, Aman B., additional

Published
2022
Full Text
View/download PDF

39. Multicenter Study for the Treatment of Sidewall versus Bifurcation Intracranial Aneurysms with Use of Woven EndoBridge (WEB)

Author

Adeeb, Nimer, primary, Dibas, Mahmoud, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Kandregula, Sandeep, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Aslan, Assala, additional, Möhlenbruch, Markus, additional, Vranic, Justin E., additional, Regenhardt, Robert W., additional, Savardekar, Amey, additional, Mamilly, Ahmed, additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Parra Farinas, Carmen, additional, Tutino, Vincent M., additional, Inoue, Yasuaki, additional, Mirshahi, Shervin, additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Brehm, Alex, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
Full Text
View/download PDF

41. Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry

Author

Mueller-Kronast, Nils H., Zaidat, Osama O., Froehler, Michael T., Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Liebeskind, David S., Jadhav, Ashutosh P., Gupta, Rishi, Hassan, Ameer E., Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin R., Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad S., Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, M. Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David H., Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammad A., Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado Almandoz, Josser E., Martin, Jerry C., and Haussen, Diogo C.

Published
2017
Full Text
View/download PDF

43. Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Author

Diestro, Jose Danilo Bengzon, primary, Dibas, Mahmoud, additional, Adeeb, Nimer, additional, Regenhardt, Robert W, additional, Vranic, Justin E, additional, Guenego, Adrien, additional, Lay, Sovann V, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Shotar, Eimad, additional, Premat, Kevin, additional, El Naamani, Kareem, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus A., additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Župančić, Vedran, additional, Hafeez, Muhammad U, additional, Rutledge, Caleb, additional, Rai, Hamid, additional, Tutino, Vincent M, additional, Mirshani, Shervin, additional, Ghozy, Sherief, additional, Harker, Pablo, additional, Alotaibi, Naif M, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Goren, Oded, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Starke, Robert M, additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Parra-Fariñas, Carmen, additional, Bres Bullrich, Maria, additional, Mayich, Michael, additional, Salem, Mohamed M, additional, Burkhardt, Jan-Karl, additional, Jankowitz, Brian T, additional, Domingo, Ricardo A, additional, Huynh, Thien, additional, Tawk, Rabih, additional, Ulfert, Christian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Stapleton, Christopher J, additional, Knopman, Jared, additional, Jabbour, Pascal, additional, Tjoumakaris, Stavropoula, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Aziz-Sultan, Mohammad A, additional, Cuellar-Saenz, Hugo H, additional, Cognard, Christophe, additional, Patel, Aman B, additional, and Dmytriw, Adam A, additional

Published
2022
Full Text
View/download PDF

44. Transradial Versus Transfemoral Access for Woven EndoBridge (WEB) Embolization of Intracranial Aneurysms: A Propensity-Score Matched Multicenter Study (P1-1.Virtual)

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Asala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
Full Text
View/download PDF

45. The Woven EndoBridge (WEB) device for the treatment of Intracranial Aneurysms: A Decade of Lessons Learned and Changes in Practice from the WorldwideWEB Consortium (P1-1.Virtual)

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Asala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
Full Text
View/download PDF

46. Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Author

Adeeb, Nimer, primary, Dibas, Mahmoud, additional, Diestro, Jose Danilo Bengzon, additional, Phan, Kevin, additional, Cuellar-Saenz, Hugo H, additional, Sweid, Ahmad, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Aslan, Assala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W, additional, Vranic, Justin E, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Župančić, Vedran, additional, Hafeez, Muhammad U, additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna L, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Starke, Robert M, additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Brehm, Alex, additional, MohammedAli, MajdEddin, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan, additional, Ducruet, Andrew, additional, Albuquerque, Felipe C, additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Stapleton, Christopher J, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B, additional, and Dmytriw, Adam A, additional

Published
2022
Full Text
View/download PDF

48. Retreatment of Residual and Recurrent Aneurysms After Embolization With the Woven EndoBridge Device: Multicenter Case Series

Author

Srinivasan, Visish M., primary, Dmytriw, Adam A., additional, Regenhardt, Robert W., additional, Vicenty-Padilla, Juan, additional, Alotaibi, Naif M., additional, Levy, Elad, additional, Waqas, Muhammad, additional, Cherian, Jacob, additional, Johnson, Jeremiah N., additional, Jabbour, Pascal, additional, Sweid, Ahmad, additional, Gross, Bradley, additional, Starke, Robert M., additional, Puri, Ajit, additional, Massari, Francesco, additional, Griessenauer, Christoph J., additional, Catapano, Joshua S., additional, Rutledge, Caleb, additional, Tanweer, Omar, additional, Yashar, Parham, additional, Cortez, Gustavo M., additional, Aziz-Sultan, Mohammad A., additional, Patel, Aman B., additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Hanel, Ricardo A., additional, Lawton, Michael T., additional, and Kan, Peter, additional

Published
2022
Full Text
View/download PDF

49. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., primary, Diestro, Jose Danilo Bengzon, additional, Dibas, Mahmoud, additional, Phan, Kevin, additional, Sweid, Ahmad, additional, Cuellar-Saenz, Hugo H., additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Sundararajan, Sri Hari, additional, Carnevale, Joseph, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Vranic, Justin E., additional, Harker, Pablo, additional, Rabinov, James D., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Abbas, Rawad, additional, Inoue, Yasuaki, additional, Capirossi, Carolina, additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Regenhardt, Robert W., additional, Ghozy, Sherief, additional, Alotaibi, Naif M., additional, Tjoumakaris, Stavropoula, additional, Starke, Robert M., additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Ulfert, Christian, additional, Asadi, Hamed, additional, Brooks, Mark, additional, Maingard, Julian, additional, Jhamb, Ashu, additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Savardekar, Amey, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Limbucci, Nicola, additional, Chen, Karen S., additional, Aziz-Sultan, Mohammad A., additional, Stapleton, Christopher J., additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Adeeb, Nimer, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results