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363 results on '"Ayers, Emmeline"'

5. Lessons from Detecting Cognitive Impairment Including Dementia (DetectCID) in Primary Care.

Author

Bernstein Sideman, Alissa, Chalmer, Rachel, Ayers, Emmeline, Gershon, Richard, Verghese, Joe, Wolf, Michael, Ansari, Asif, Arvanitis, Marina, Bui, Nhat, Chen, Pei, Chodos, Anna, Corriveau, Roderick, Curtis, Laura, Ehrlich, Amy R, Tomaszewski Farias, Sarah E, Goode, Collette, Hill-Sakurai, Laura, Nowinski, Cindy J, Premkumar, Mukund, Rankin, Katherine P, Ritchie, Christine S, Tsoy, Elena, Weiss, Erica, and Possin, Katherine L

Subjects
Humans, Dementia, Diagnosis, Differential, Cognition Disorders, Aged, Primary Health Care, Cognitive Dysfunction, Cognitive assessment, dementia, detection, diagnosis, implementation evaluation, mild cognitive impairment, primary care, Alzheimer's Disease, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Behavioral and Social Science, Clinical Research, Brain Disorders, Health Services, Neurodegenerative, Aging, Good Health and Well Being, Clinical Sciences, Neurosciences, Cognitive Sciences, Neurology & Neurosurgery
Abstract

BackgroundCognitive impairment, including dementia, is frequently under-detected in primary care. The Consortium for Detecting Cognitive Impairment, including Dementia (DetectCID) convenes three multidisciplinary teams that are testing novel paradigms to improve the frequency and quality of patient evaluations for detecting cognitive impairment in primary care and appropriate follow-up.ObjectiveOur objective was to characterize the three paradigms, including similarities and differences, and to identify common key lessons from implementation.MethodsA qualitative evaluation study with dementia specialists who were implementing the detection paradigms. Data was analyzed using content analysis.ResultsWe identified core components of each paradigm. Key lessons emphasized the importance of engaging primary care teams, enabling primary care providers to diagnose cognitive disorders and provide ongoing care support, integrating with the electronic health record, and ensuring that paradigms address the needs of diverse populations.ConclusionApproaches are needed that address the arc of care from identifying a concern to post-diagnostic management, are efficient and adaptable to primary care workflows, and address a diverse aging population. Our work highlights approaches to partnering with primary care that could be useful across specialties and paves the way for developing future paradigms that improve differential diagnosis of symptomatic cognitive impairment, identifying not only its presence but also its specific syndrome or etiology.

Published
2022

11. Randomized Controlled Trial of Social Ballroom Dancing and Treadmill Walking: Preliminary Findings on Executive Function and Neuroplasticity From Dementia-at-Risk Older Adults.

Author

Blumen, Helena M., Ayers, Emmeline, Wang, Cuiling, Ambrose, Anne F., Jayakody, Oshadi, and Verghese, Joe

Subjects
DEMENTIA risk factors, HIPPOCAMPUS physiology, EXECUTIVE function, BRAIN, COVID-19, NEUROPLASTICITY, TREADMILLS, MAGNETIC resonance imaging, MEDICAL screening, RISK assessment, RANDOMIZED controlled trials, WALKING, DEMENTIA, EXERCISE, DESCRIPTIVE statistics, RESEARCH funding, DANCE
Abstract

This randomized controlled trial (NCT03475316) examined the relative efficacy of 6 months of social ballroom dancing and treadmill walking on a composite executive function score, generated from digit symbol substitution test, flanker interference, and walking while talking tasks. Brain activation during functional magnetic resonance imaging (fMRI) versions of these executive function tasks were secondary outcomes. Twenty-five dementia-at-risk older adults (memory impairment screen score of ≥3 to ≤6 and/or an Alzheimer's disease-8 Dementia Screening Interview of ≥1) were randomized in June 2019 to March 2020—16 completed the intervention before study termination due to the COVID-19 (eight in each group). Composite executive function scores improved post-intervention in both groups, but there was no evidence for between-group differences. Social dancing, however, generated greater improvements on digit symbol substitution test than treadmill walking. No intervention-related differences were observed in brain activation—although less hippocampal atrophy (tertiary) was observed following social dancing than treadmill walking. These preliminary findings are promising but need to be confirmed in future large-scale and sufficiently powered randomized controlled trials. [ABSTRACT FROM AUTHOR]

Published
2023
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14. Linking dementia pathology and alteration in brain activation to complex daily functional decline during the preclinical dementia stages (Preprint)

Author

De Sanctis, Pierfilippo, primary, Mahoney, Jeannette R., additional, Wagner, Johanna, additional, Blumen, Helena M., additional, Mowrey, Wenzhu, additional, Ayers, Emmeline, additional, Schneider, Claudia, additional, Orellana, Natasha, additional, Molholm, Sophie, additional, and Verghese, Joe, additional

Published
2024
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24. Epidemiology of Motoric Cognitive Risk Syndrome in the Kerala Einstein Study: Protocol for a Prospective Cohort Study

Author

Sathyan, Sanish, primary, Ayers, Emmeline, additional, Blumen, Helena, additional, Weiss, Erica F, additional, Adhikari, Dristi, additional, Stimmel, Marnina, additional, Abdulsalam, Kizhakkaniyakath, additional, Noone, Mohan, additional, George, Roy K, additional, Ceide, Mirnova, additional, Ambrose, Anne Felicia, additional, Wang, Cuiling, additional, Narayanan, Poornima, additional, Sureshbabu, Sachin, additional, Shaji, Kunnukatil S, additional, Sigamani, Alben, additional, Mathuranath, Pavagada S, additional, Pradeep, Vayyattu G, additional, and Verghese, Joe, additional

Published
2023
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25. Epidemiology of Motoric Cognitive Risk Syndrome in the Kerala Einstein Study: Protocol for a Prospective Cohort Study (Preprint)

Author

Sathyan, Sanish, primary, Ayers, Emmeline, additional, Blumen, Helena, additional, Weiss, Erica F, additional, Adhikari, Dristi, additional, Stimmel, Marnina, additional, Abdulsalam, Kizhakkaniyakath, additional, Noone, Mohan, additional, George, Roy K, additional, Ceide, Mirnova, additional, Ambrose, Anne Felicia, additional, Wang, Cuiling, additional, Narayanan, Poornima, additional, Sureshbabu, Sachin, additional, Shaji, Kunnukatil S, additional, Sigamani, Alben, additional, Mathuranath, Pavagada S, additional, Pradeep, Vayyattu G, additional, and Verghese, Joe, additional

Published
2023
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