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Cholera is a public health problem around the world, and it is endemic in Africa, parts of Asia, the Middle East as well as South and Central America. This review characterizes an cholera outbreak in Nigeria in 2017/2018. On the basis of own experiences and the analysis of historical outbreaks, the cholera strains, mode of transmission, signs and symptoms, and most important the prevention and control measures are identified. Untreated, the lethality of cholera is up to 70%. Therefore, a multifaceted approach including public policy, surveillance, water purification and hygiene, community sensitization, and the use of oral cholera vaccination (OVC) is vital to prevent, control, and reduce the cholera mortality rate. It is recommended that the government pass legislation to implement preventive and surveillance measures, e.g., invest in drinking water systems, sanitation systems and sewage treatment, and promote public education on basic hygiene. The latter includes boiling and treating water before drinking, washing hands frequently with soap and clean water, thoroughly cooking food before consumption, avoiding open defecation, disposing of wastes properly, and immediately taking anyone with signs and symptoms of cholera such as watery diarrhea to the hospital for treatment.

The COVID-19 vaccination campaign is an ongoing worldwide effort to vaccinate large numbers of people against COVID-19 in order to ensure protection from the disease, control the rate of infection, reduce severe outcomes, and get back to normal life. Most African countries had a delay in the initiation of their COVID-19 vaccine national rollout compared to other regions in the world, and the goal of the immunization exercise in the continent is to vaccinate over 60% of the African population to attain herd immunity. Over the years, vaccination programmes are usually faced with challenges in Africa because of numerous factors. So far, some of the major challenges threatening the success of the COVID-19 vaccination rollout in most African countries includes the slow onset of the vaccination exercise, limited funds, concerns around vaccine safety and uncertainties, storage requirements and regulatory hurdles for vaccines, limited shelf life of COVID-19 vaccines, inability to access vulnerable communities in a timely fashion, problems around the use of different vaccines, and wars and conflicts. The solutions and other imperative recommendations to these challenges were provided so as to optimize the vaccination programme and to achieve an appreciable success in the COVID-19 vaccination programme on the continent. In conclusion, a holistic and timely planning, fast execution of plans, rigorous community involvement, and a robust multi-sectoral partnership will ensure a successful COVID-19 vaccination campaign in Africa. [ABSTRACT FROM AUTHOR]