38 results on '"Ayele, Henok Tadesse"'
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2. Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Griswold, Max G, Fullman, Nancy, Hawley, Caitlin, Arian, Nicholas, Zimsen, Stephanie RM, Tymeson, Hayley D, Venkateswaran, Vidhya, Tapp, Austin Douglas, Forouzanfar, Mohammad H, Salama, Joseph S, Abate, Kalkidan Hassen, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abdulkader, Rizwan Suliankatchi, Abebe, Zegeye, Aboyans, Victor, Abrar, Mohammed Mehdi, Acharya, Pawan, Adetokunboh, Olatunji O, Adhikari, Tara Ballav, Adsuar, Jose C, Afarideh, Mohsen, Agardh, Emilie Elisabet, Agarwal, Gina, Aghayan, Sargis Aghasi, Agrawal, Sutapa, Ahmed, Muktar Beshir, Akibu, Mohammed, Akinyemiju, Tomi, Akseer, Nadia, Asfoor, Deena H Al, Al-Aly, Ziyad, Alahdab, Fares, Alam, Khurshid, Albujeer, Ammar, Alene, Kefyalew Addis, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F, Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H, Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Béjot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A, Bensenor, Isabela M, Bernabe, Eduardo, Bernstein, Robert S, Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjørge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, Soufiane, Bragazzi, Nicola Luigi, Brenner, Hermann, and Butt, Zahid A
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Epidemiology ,Public Health ,Health Sciences ,Alcoholism ,Alcohol Use and Health ,Aging ,Prevention ,Behavioral and Social Science ,Substance Misuse ,Women's Health ,2.4 Surveillance and distribution ,Cancer ,Oral and gastrointestinal ,Stroke ,Good Health and Well Being ,Adolescent ,Adult ,Age Distribution ,Aged ,Aged ,80 and over ,Alcohol Drinking ,Cause of Death ,Commerce ,Female ,Global Burden of Disease ,Global Health ,Humans ,Male ,Middle Aged ,Observational Studies as Topic ,Population Surveillance ,Prevalence ,Prospective Studies ,Quality-Adjusted Life Years ,Retrospective Studies ,Risk Assessment ,Risk Factors ,Sex Distribution ,Young Adult ,GBD 2016 Alcohol Collaborators ,Medical and Health Sciences ,General & Internal Medicine ,Biomedical and clinical sciences ,Health sciences - Abstract
BackgroundAlcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older.MethodsUsing 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health.FindingsGlobally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5-3·0) of age-standardised female deaths and 6·8% (5·8-8·0) of age-standardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2-4·3) of female deaths and 12·2% (10·8-13·6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2·3% (95% UI 2·0-2·6) and male attributable DALYs were 8·9% (7·8-9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0-1·7] of total deaths), road injuries (1·2% [0·7-1·9]), and self-harm (1·1% [0·6-1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2-33·3) of total alcohol-attributable female deaths and 18·9% (15·3-22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0-0·8) standard drinks per week.InterpretationAlcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that the risk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.FundingBill & Melinda Gates Foundation.
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- 2018
3. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016
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Collaborators, GBD 2016 Healthcare Access and Quality, Fullman, Nancy, Yearwood, Jamal, Abay, Solomon M, Abbafati, Cristiana, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abebe, Zegeye, Abebo, Teshome Abuka, Aboyans, Victor, Abraha, Haftom Niguse, Abreu, Daisy MX, Abu-Raddad, Laith J, Adane, Akilew Awoke, Adedoyin, Rufus Adesoji, Adetokunboh, Olatunji, Adhikari, Tara Ballav, Afarideh, Mohsen, Afshin, Ashkan, Agarwal, Gina, Agius, Dominic, Agrawal, Anurag, Agrawal, Sutapa, Kiadaliri, Aliasghar Ahmad, Aichour, Miloud Taki Eddine, Akibu, Mohammed, Akinyemi, Rufus Olusola, Akinyemiju, Tomi F, Akseer, Nadia, Lami, Faris Hasan Al, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Tahiya, Alasfoor, Deena, Albittar, Mohammed I, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed M, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine, Alomari, Mahmoud A, Al-Raddadi, Rajaa, Alsharif, Ubai, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amenu, Kebede, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla, Andrei, Catalina Liliana, Androudi, Sofia, Antonio, Carl Abelardo T, Araújo, Valdelaine EM, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna Kumar, Asayesh, Hamid, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Asghar, Rana Jawad, Ashebir, Mengistu Mitiku, Asseffa, Netsanet Abera, Atey, Tesfay Mehari, Atre, Sachin R, Atteraya, Madhu S, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Quintanilla, Beatriz Paulina Ayala, Ayalew, Animut Alebel, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe Betrand, Azzopardi, Peter, Azzopardi-Muscat, Natasha, Babalola, Tesleem Kayode, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Banerjee, Amitava, Banstola, Amrit, Barber, Ryan M, Barboza, Miguel A, Barker-Collo, Suzanne L, Bärnighausen, Till, Barquera, Simon, Barrero, Lope H, Bassat, Quique, Basu, Sanjay, Baune, Bernhard T, Bazargan-Hejazi, Shahrzad, and Bedi, Neeraj
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Health Services and Systems ,Public Health ,Health Sciences ,Clinical Research ,Biodefense ,Prevention ,Vaccine Related ,Good Health and Well Being ,Communicable Diseases ,Global Burden of Disease ,Health Services Accessibility ,Humans ,Noncommunicable Diseases ,Quality of Health Care ,Wounds and Injuries ,GBD 2016 Healthcare Access and Quality Collaborators ,Medical and Health Sciences ,General & Internal Medicine ,Biomedical and clinical sciences ,Health sciences - Abstract
BackgroundA key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016.MethodsDrawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0-100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best); we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0-100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derived from the broader GBD study and other data sources, we examined relationships between national HAQ Index scores and potential correlates of performance, such as total health spending per capita.FindingsIn 2016, HAQ Index performance spanned from a high of 97·1 (95% UI 95·8-98·1) in Iceland, followed by 96·6 (94·9-97·9) in Norway and 96·1 (94·5-97·3) in the Netherlands, to values as low as 18·6 (13·1-24·4) in the Central African Republic, 19·0 (14·3-23·7) in Somalia, and 23·4 (20·2-26·8) in Guinea-Bissau. The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. Striking subnational disparities emerged in personal health-care access and quality, with China and India having particularly large gaps between locations with the highest and lowest scores in 2016. In China, performance ranged from 91·5 (89·1-93·6) in Beijing to 48·0 (43·4-53·2) in Tibet (a 43·5-point difference), while India saw a 30·8-point disparity, from 64·8 (59·6-68·8) in Goa to 34·0 (30·3-38·1) in Assam. Japan recorded the smallest range in subnational HAQ performance in 2016 (a 4·8-point difference), whereas differences between subnational locations with the highest and lowest HAQ Index values were more than two times as high for the USA and three times as high for England. State-level gaps in the HAQ Index in Mexico somewhat narrowed from 1990 to 2016 (from a 20·9-point to 17·0-point difference), whereas in Brazil, disparities slightly increased across states during this time (a 17·2-point to 20·4-point difference). Performance on the HAQ Index showed strong linkages to overall development, with high and high-middle SDI countries generally having higher scores and faster gains for non-communicable diseases. Nonetheless, countries across the development spectrum saw substantial gains in some key health service areas from 2000 to 2016, most notably vaccine-preventable diseases. Overall, national performance on the HAQ Index was positively associated with higher levels of total health spending per capita, as well as health systems inputs, but these relationships were quite heterogeneous, particularly among low-to-middle SDI countries.InterpretationGBD 2016 provides a more detailed understanding of past success and current challenges in improving personal health-care access and quality worldwide. Despite substantial gains since 2000, many low-SDI and middle-SDI countries face considerable challenges unless heightened policy action and investments focus on advancing access to and quality of health care across key health services, especially non-communicable diseases. Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. Alongside initiatives to strengthen public health programmes, the pursuit of universal health coverage hinges upon improving both access and quality worldwide, and thus requires adopting a more comprehensive view-and subsequent provision-of quality health care for all populations.FundingBill & Melinda Gates Foundation.
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- 2018
4. Trends in the pharmacological treatment of benign prostatic hyperplasia in the UK from 1998 to 2016: a population-based cohort study
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Ayele, Henok Tadesse, Reynier, Pauline, Azoulay, Laurent, Platt, Robert W., Cabaussel, Josselin, Benayoun, Serge, and Filion, Kristian B.
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- 2021
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5. Global, regional, and national burden of tuberculosis, 1990–2016: results from the Global Burden of Diseases, Injuries, and Risk Factors 2016 Study
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Kyu, Hmwe Hmwe, Maddison, Emilie R, Henry, Nathaniel J, Ledesma, Jorge R, Wiens, Kirsten E, Reiner, Robert, Jr, Biehl, Molly H, Shields, Chloe, Osgood-Zimmerman, Aaron, Ross, Jennifer M, Carter, Austin, Frank, Tahvi D, Wang, Haidong, Srinivasan, Vinay, Agarwal, Sanjay Kumar, Alahdab, Fares, Alene, Kefyalew Addis, Ali, Beriwan Abdulqadir, Alvis-Guzman, Nelson, Andrews, Jason R, Antonio, Carl Abelardo T, Atique, Suleman, Atre, Sachin R, Awasthi, Ashish, Ayele, Henok Tadesse, Badali, Hamid, Badawi, Alaa, Barac, Aleksandra, Bedi, Neeraj, Behzadifar, Masoud, Behzadifar, Meysam, Bekele, Bayu Begashaw, Belay, Saba Abraham, Bensenor, Isabela M, Butt, Zahid A, Carvalho, Félix, Cercy, Kelly, Christopher, Devasahayam J, Daba, Alemneh Kabeta, Dandona, Lalit, Dandona, Rakhi, Daryani, Ahmad, Demeke, Feleke Mekonnen, Deribe, Kebede, Dharmaratne, Samath Dhamminda, Doku, David Teye, Dubey, Manisha, Edessa, Dumessa, El-Khatib, Ziad, Enany, Shymaa, Fernandes, Eduarda, Fischer, Florian, Garcia-Basteiro, Alberto L, Gebre, Abadi Kahsu, Gebregergs, Gebremedhin Berhe, Gebremichael, Teklu Gebrehiwo, Gelano, Tilayie Feto, Geremew, Demeke, Gona, Philimon N, Goodridge, Amador, Gupta, Rahul, Haghparast Bidgoli, Hassan, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hedayati, Mohammad T. Tadesse, Henok, Andualem, Hostiuc, Sorin, Hussen, Mamusha Aman, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Jacobsen, Kathryn H, Johnson, Sarah C, Jonas, Jost B., Kahsay, Amaha, Kant, Surya, Kasaeian, Amir, Kassa, Tesfaye Dessale, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khalil, Ibrahim, Khan, Ejaz Ahmad, Khang, Young-Ho, Kim, Yun Jin, Kochhar, Sonali, Koyanagi, Ai, Krohn, Kristopher J, Kumar, G Anil, Lakew, Ayenew Molla, Leshargie, Cheru Tesema, Lodha, Rakesh, Macarayan, Erlyn Rachelle King, Majdzadeh, Reza, Martins-Melo, Francisco Rogerlândio, Melese, Addisu, Memish, Ziad A, Mendoza, Walter, Mengistu, Desalegn Tadese, Mengistu, Getnet, Mestrovic, Tomislav, Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammed, Shafiu, Mokdad, Ali H, Moosazadeh, Mahmood, Mousavi, Seyyed Meysam, Mustafa, Ghulam, Nachega, Jean B, Nguyen, Long Hoang, Nguyen, Son Hoang, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Nong, Vuong Minh, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T, Oren, Eyal, Pereira, David M., Prakash, Swayam, Qorbani, Mostafa, Rafay, Anwar, Rai, Rajesh Kumar, Ram, Usha, Rubino, Salvatore, Safiri, Saeid, Salomon, Joshua A, Samy, Abdallah M., Sartorius, Benn, Satpathy, Maheswar, Seyedmousavi, Seyedmojtaba, Sharif, Mehdi, Silva, João Pedro, Silveira, Dayane Gabriele Alves, Singh, Jasvinder A, Sreeramareddy, Chandrashekhar T, Tran, Bach Xuan, Tsadik, Afewerki Gebremeskel, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Uthman, Olalekan A, Vlassov, Vasily, Vollset, Stein Emil, Vu, Giang, Weldegebreal, Fitsum, Werdecker, Andrea, Yimer, Ebrahim M, Yonemoto, Naohiro, Yotebieng, Marcel, Naghavi, Mohsen, Vos, Theo, Hay, Simon I, and Murray, Christopher J L
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- 2018
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6. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016
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Troeger, Christopher, Blacker, Brigette F, Khalil, Ibrahim A, Rao, Puja C, Cao, Shujin, Zimsen, Stephanie RM, Albertson, Samuel B, Stanaway, Jeffery D, Deshpande, Aniruddha, Abebe, Zegeye, Alvis-Guzman, Nelson, Amare, Azmeraw T, Asgedom, Solomon W, Anteneh, Zelalem Alamrew, Antonio, Carl Abelardo T, Aremu, Olatunde, Asfaw, Ephrem Tsegay, Atey, Tesfay Mehari, Atique, Suleman, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Ayele, Henok Tadesse, Barac, Aleksandra, Barreto, Mauricio L, Bassat, Quique, Belay, Saba Abraham, Bensenor, Isabela M, Bhutta, Zulfiqar A, Bijani, Ali, Bizuneh, Hailemichael, Castañeda-Orjuela, Carlos A, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Do, Huyen Phuc, Dubey, Manisha, Dubljanin, Eleonora, Edessa, Dumessa, Endries, Aman Yesuf, Eshrati, Babak, Farag, Tamer, Feyissa, Garumma Tolu, Foreman, Kyle J, Forouzanfar, Mohammad H, Fullman, Nancy, Gething, Peter W, Gishu, Melkamu Dedefo, Godwin, William W, Gugnani, Harish Chander, Gupta, Rahul, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hibstu, Desalegn Tsegaw, Ilesanmi, Olayinka S, Jonas, Jost B, Kahsay, Amaha, Kang, Gagandeep, Kasaeian, Amir, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Muhammad Ali, Khang, Young-Ho, Kissoon, Niranjan, Kochhar, Sonali, Kotloff, Karen L, Koyanagi, Ai, Kumar, G Anil, Magdy Abd El Razek, Hassan, Malekzadeh, Reza, Malta, Deborah Carvalho, Mehata, Suresh, Mendoza, Walter, Mengistu, Desalegn Tadese, Menota, Bereket Gebremichael, Mezgebe, Haftay Berhane, Mlashu, Fitsum Weldegebreal, Murthy, Srinivas, Naik, Gurudatta A, Nguyen, Cuong Tat, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Ogbo, Felix Akpojene, Olagunju, Andrew Toyin, Paudel, Deepak, Platts-Mills, James A, Qorbani, Mostafa, Rafay, Anwar, Rai, Rajesh Kumar, Rana, Saleem M, Ranabhat, Chhabi Lal, Rasella, Davide, Ray, Sarah E, Reis, Cesar, Renzaho, Andre MN, Rezai, Mohammad Sadegh, Ruhago, George Mugambage, Safiri, Saeid, Salomon, Joshua A, Sanabria, Juan Ramon, Sartorius, Benn, Sawhney, Monika, Sepanlou, Sadaf G, Shigematsu, Mika, Sisay, Mekonnen, Somayaji, Ranjani, Sreeramareddy, Chandrashekhar T, Sykes, Bryan L, Taffere, Getachew Redae, Topor-Madry, Roman, Tran, Bach Xuan, Tuem, Kald Beshir, Ukwaja, Kingsley Nnanna, Vollset, Stein Emil, Walson, Judd L, Weaver, Marcia R, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Workicho, Abdulhalik, Yenesew, Muluken, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, El Sayed Zaki, Maysaa, Vos, Theo, Lim, Stephen S, Naghavi, Mohsen, Murray, Christopher JL, Mokdad, Ali H, Hay, Simon I, and Reiner, Robert C, Jr
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- 2018
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7. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Troeger, Christopher, Blacker, Brigette, Khalil, Ibrahim A, Rao, Puja C, Cao, Jackie, Zimsen, Stephanie R M, Albertson, Samuel B, Deshpande, Aniruddha, Farag, Tamer, Abebe, Zegeye, Adetifa, Ifedayo Morayo O, Adhikari, Tara Ballav, Akibu, Mohammed, Al Lami, Faris Hasan, Al-Eyadhy, Ayman, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amoako, Yaw Ampem, Antonio, Carl Abelardo T, Aremu, Olatunde, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Atey, Tesfay Mehari, Attia, Engi Farouk, Avokpaho, Euripide Frinel G Arthur, Ayele, Henok Tadesse, Ayuk, Tambe Betrand, Balakrishnan, Kalpana, Barac, Aleksandra, Bassat, Quique, Behzadifar, Masoud, Behzadifar, Meysam, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Bijani, Ali, Brauer, Michael, Brown, Alexandria, Camargos, Paulo A M, Castañeda-Orjuela, Carlos A, Colombara, Danny, Conti, Sara, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Do, Huyen Phuc, Dubljanin, Eleonora, Edessa, Dumessa, Elkout, Hajer, Endries, Aman Yesuf, Fijabi, Daniel Obadare, Foreman, Kyle J, Forouzanfar, Mohammad H, Fullman, Nancy, Garcia-Basteiro, Alberto L, Gessner, Bradford D, Gething, Peter W, Gupta, Rahul, Gupta, Tarun, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hedayati, Mohammad T, Heidari, Mohsen, Hibstu, Desalegn Tsegaw, Horita, Nobuyuki, Ilesanmi, Olayinka S, Jakovljevic, Mihajlo B, Jamal, Amr A, Kahsay, Amaha, Kasaeian, Amir, Kassa, Dessalegn Haile, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Md Nuruzzaman, Khang, Young-Ho, Kim, Yun Jin, Kissoon, Niranjan, Knibbs, Luke D, Kochhar, Sonali, Koul, Parvaiz A, Kumar, G Anil, Lodha, Rakesh, Magdy Abd El Razek, Hassan, Malta, Deborah Carvalho, Mathew, Joseph L, Mengistu, Desalegn Tadese, Mezgebe, Haftay Berhane, Mohammad, Karzan Abdulmuhsin, Mohammed, Mohammed A, Momeniha, Fatemeh, Murthy, Srinivas, Nguyen, Cuong Tat, Nielsen, Katie R, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Oren, Eyal, Ortiz, Justin R, PA, Mahesh, Postma, Maarten J, Qorbani, Mostafa, Quansah, Reginald, Rai, Rajesh Kumar, Rana, Saleem M, Ranabhat, Chhabi Lal, Ray, Sarah E, Rezai, Mohammad Sadegh, Ruhago, George Mugambage, Safiri, Saeid, Salomon, Joshua A, Sartorius, Benn, Savic, Miloje, Sawhney, Monika, She, Jun, Sheikh, Aziz, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Singh, Jasvinder A, Somayaji, Ranjani, Stanaway, Jeffrey D, Sufiyan, Muawiyyah Babale, Taffere, Getachew Redae, Temsah, Mohamad-Hani, Thompson, Matthew J, Tobe-Gai, Ruoyan, Topor-Madry, Roman, Tran, Bach Xuan, Tran, Tung Thanh, Tuem, Kald Beshir, Ukwaja, Kingsley Nnanna, Vollset, Stein Emil, Walson, Judd L, Weldegebreal, Fitsum, Werdecker, Andrea, West, T Eoin, Yonemoto, Naohiro, Zaki, Maysaa El Sayed, Zhou, Lei, Zodpey, Sanjay, Vos, Theo, Naghavi, Mohsen, Lim, Stephen S, Mokdad, Ali H, Murray, Christopher J L, Hay, Simon I, and Reiner, Robert C, Jr
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- 2018
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8. Response to: Real‐World Data on the Risk of Ventricular Arrhythmias with Sulfonamides
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Islam, Nehal, primary, Ayele, Henok Tadesse, additional, Yu, Oriana H. Y., additional, Douros, Antonios, additional, and Filion, Kristian B., additional
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- 2022
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9. 5‐α reductase inhibitors and the risk of anaemia among men with benign prostatic hyperplasia: A population‐based cohort study
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Ayele, Henok Tadesse, primary, Douros, Antonios, additional, and Filion, Kristian B., additional
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- 2022
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10. Testosterone replacement therapy and the risk of venous thromboembolism: A systematic review and meta-analysis of randomized controlled trials
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Ayele, Henok Tadesse, primary, Brunetti, Vanessa C., additional, Renoux, Christel, additional, Tagalakis, Vicky, additional, and Filion, Kristian B., additional
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- 2021
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11. Type 2 diabetes mellitus and risk of community-acquired pneumonia: a systematic review and meta-analysis of observational studies
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Brunetti, Vanessa C., primary, Ayele, Henok Tadesse, additional, Yu, Oriana Hoi Yun, additional, Ernst, Pierre, additional, and Filion, Kristian B., additional
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- 2021
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12. Trends in the pharmacological treatment of benign prostatic hyperplasia in the UK from 1998 to 2016: a population-based cohort study
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Ayele, Henok Tadesse, primary, Reynier, Pauline, additional, Azoulay, Laurent, additional, Platt, Robert W., additional, Cabaussel, Josselin, additional, Benayoun, Serge, additional, and Filion, Kristian B., additional
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- 2020
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13. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
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Lozano, Rafael, Fullman, Nancy, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdel-Rahman, Omar, Abdi, Alireza, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Nebiyu Dereje, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F, Abil, Olifan Zewdie, Aboyans, Victor, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Abu-Rmeileh, Niveen Me, Abyu, Gebre Y, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Acharya, Pawan, Adamu, Abdu A, Adebayo, Oladimeji M, Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O, Adhena, Beyene Meressa, Adhikari, Tara Ballav, Adib, Mina G, Adou, Arsène Kouablan, Adsuar, Jose C, Afarideh, Mohsen, Afshari, Mahdi, Afshin, Ashkan, Agarwal, Gina, Aghayan, Sargis Aghasi, Agius, Dominic, Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Ahmed, Sayem, Akalu, Temesgen Yihunie, Akanda, Ali S, Akbari, Mohammad Esmaeil, Akibu, Mohammed, Akinyemi, Rufus Olusola, Akinyemiju, Tomi, Akseer, Nadia, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Tahiya, Albujeer, Ammar, Alebel, Animut, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Alhabib, Samia, Ali, Raghib, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine A, Almasi, Ali, Al-Maskari, Fatma, Al-Mekhlafi, Hesham M, Alonso, Jordi, Al-Raddadi, Rajaa M, Alsharif, Ubai, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amenu, Kebede, Amini, Erfan, Ammar, Walid, Anber, Nahla Hamed, Anderson, Jason A, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansari, Hossein, Ansariadi, Ansariadi, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Appiah, Lambert Tetteh, Aremu, Olatunde, Areri, Habtamu Abera, Ärnlöv, Johan, Arora, Monika, Aryal, Krishna K, Asayesh, Hamid, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Asghar, Rana Jawad, Assadi, Reza, Ataro, Zerihun, Atique, Suleman, Atre, Sachin R, Atteraya, Madhu Sudhan, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F G A, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Ayele, Henok Tadesse, Ayele, Yohanes, Ayer, Rakesh, Azarpazhooh, Mahmoud Reza, Azzopardi, Peter S, Azzopardi-Muscat, Natasha, Babalola, Tesleem Kayode, Babazadeh, Arefeh, Badali, Hamid, Badawi, Alaa, Balakrishnan, Kalpana, Bali, Ayele Geleto, Banach, Maciej, Banerjee, Amitava, Banoub, Joseph Adel Mattar, Banstola, Amrit, Barac, Aleksandra, Barboza, Miguel A, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barrero, Lope H, Barthelemy, Celine M, Bassat, Quique, Basu, Arindam, Basu, Sanjay, Battista, Robert J, Baune, Bernhard T, Baynes, Habtamu Wondifraw, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Meysam, Béjot, Yannick, Bekele, Bayu 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GENDER-DIFFERENCES ,SUICIDE ,Medicine (all) ,Burden of Disease Study 2017 ,SDG ,CONSUMPTION ,11 Medical And Health Sciences ,GBD, Sustainable Development Goals ,PREVENTION ,ALCOHOL-USE ,CARDIOVASCULAR-DISEASE ,SMOKING PREVALENCE ,General & Internal Medicine ,factors risk ,Medicine and Health Sciences ,Human medicine ,CESSATION ,PERSPECTIVE ,TRANSITION - Abstract
Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health -related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990-2017, projected indicators to 2030, and analysed global attainment. Methods We measured progress on 41 health-related S DG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health related SDG index, we transformed the value for each indicator on a scale of 0-100, with 0 as the 2.5th percentile and 100 as the 97.5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings The global median health-related SDG index in 2017 was 59.4 (IQR 35.4-67.3), ranging from a low of 11.6 (95% uncertainty interval 9.6-14.0) to a high of 84.9 (83.1-86.7). SDG index values in countries assessed at the subnational level varied substantially particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attaimnent by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation The GBD study offers a unique, robust platform for monitoring the health -related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health -related SDG indicators, NCDs, NCD-related risks, and violence -related indicators will require a concerted shift away from what might have driven past gains curative interventions in the case of NCDs towards multisectoral, prevention -oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the S DGs. What is clear is that our actions or inaction today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030. Copyright (C) 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
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14. Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
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Jamal A, Yentür, Gökalp Kadri, Yeshaneh, Alex, Yimer, Ebrahim M, Yip, Paul, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, York, Hunter W, Yotebieng, Marcel, Younis, Mustafa Z, Yousefifard, Mahmoud, Yu, Chuanhua, Zachariah, Geevar, Zadnik, Vesna, Zafar, Shamsa, Zaidi, Zoubida, Zaman, Sojib Bin, Zamani, Mohammad, Zare, Zohreh, Zeeb, Hajo, Zeleke, Mulugeta Molla, Zenebe, Zerihun Menlkalew, Zerfu, Taddese Alemu, Zhang, Kai, Zhang, Xueying, Zhou, Maigeng, Zhu, Jun, Zodpey, Sanjay, Zucker, Inbar, Zuhlke, Liesl Joanna J, Lopez, Alan D, Gakidou, Emmanuela, Murray, Christopher J L, GBD 2017 Mortality Collaborators, Dicker, D, Nguyen, G, Abate, D, Abate, Kh, Abay, Sm, Abbafati, C, Abbasi, N, Abbastabar, H, Abd-Allah, F, Abdela, J, Abdelalim, A, Abdel-Rahman, O, Abdi, A, Abdollahpour, I, Abdulkader, R, Abdurahman, Aa, Abebe, Ht, Abebe, M, Abebe, Z, Abebo, Ta, Aboyans, V, Abraha, Hn, Abrham, Ar, Abu-Raddad, Lj, Abu-Rmeileh, Nm, Accrombessi, Mmk, Acharya, P, Adebayo, Om, Adedeji, Ia, Adedoyin, 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Child mortality ,Alnæmi ,Dánartíðni ,Heilsufar ,GBD ,Börn ,Dauði ,Almennar lyflækningar ,Fullorðnir ,General & Internal Medicine ,parasitic diseases ,Psychology ,age-specific mortality ,Estimating adult mortality ,Medicine (all) ,HIV ,11 Medical And Health Sciences ,General Medicine ,All-cause mortality ,humanities ,Countries ,Death ,mortality, national ,Sálfræði ,Health ,GBD, mortality ,Human medicine ,Trends - Abstract
The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders. Data for this research was provided by MEASURE Evaluation, funded by the United States Agency for International Development (USAID). Views expressed do not necessarily reflect those of USAID, the US Government, or MEASURE Evaluation. The Palestinian Central Bureau of Statistics granted the researchers access to relevant data in accordance with licence no. SLN2014-3-170, after subjecting data to processing aiming to preserve the confidentiality of individual data in accordance with the General Statistics Law-2000. The researchers are solely responsible for the conclusions and inferences drawn upon available data., Background Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Methods The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specific mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in different components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. Findings Globally, 18·7% (95% uncertainty interval 18·4–19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2–59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5–49·6) to 70·5 years (70·1–70·8) for men and from 52·9 years (51·7–54·0) to 75·6 years (75·3–75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5–51·7) for men in the Central African Republic to 87·6 years (86·9–88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3–238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6–42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2–5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. Interpretation This analysis of age-sex-specific mortality shows that there are remarkably complex patterns in population mortality across countries. The findings of this study highlight global successes, such as the large decline in under-5 mortality, which reflects significant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing., Research reported in this publication was supported by the Bill & Melinda Gates Foundation, the University of Melbourne, Public Health England, the Norwegian Institute of Public Health, St. Jude Children's Research Hospital, the National Institute on Aging of the National Institutes of Health (award P30AG047845), and the National Institute of Mental Health of the National Institutes of Health (award R01MH110163).
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- 2018
15. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017
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Fitzmaurice, Christina, Abate, Degu, Abbasi, Naghmeh, Abbastabar, Hedayat, Abd-Allah, Foad, Abdel-Rahman, Omar, Abdelalim, Ahmed, Abdoli, Amir, Abdollahpour, Ibrahim, Abdulle, Abdishakur SM, Abebe, Nebiyu Dereje, Abraha, Haftom Niguse, Abu-Raddad, Laith Jamal, Abualhasan, Ahmed, Adedeji, Isaac Akinkunmi, Advani, Shailesh M, Afarideh, Mohsen, Afshari, Mahdi, Aghaali, Mohammad, Agius, Dominic, Agrawal, Sutapa, Ahmadi, Ayat, Ahmadian, Elham, Ahmadpour, Ehsan, Ahmed, Muktar Beshir, Akbari, Mohammad Esmaeil, Akinyemiju, Tomi, Al-Aly, Ziyad, AlAbdulKader, Assim M, Alahdab, Fares, Alam, Tahiya, Alamene, Genet Melak, Alemnew, Birhan Tamene T, Alene, Kefyalew Addis, Alinia, Cyrus, Alipour, Vahid, Aljunid, Syed Mohamed, Bakeshei, Fatemeh Allah, Almadi, Majid Abdulrahman Hamad, Almasi-Hashiani, Amir, Alsharif, Ubai, Alsowaidi, Shirina, Alvis-Guzman, Nelson, Amini, Erfan, Amini, Saeed, Amoako, Yaw Ampem, Anbari, Zohreh, Anber, Nahla Hamed, Andrei, Catalina Liliana, Anjomshoa, Mina, Ansari, Fereshteh, Ansariadi, Ansariadi, Appiah, Seth Christopher Yaw, Arab-Zozani, Morteza, Arabloo, Jalal, Arefi, Zohreh, Aremu, Olatunde, Areri, Habtamu Abera, Artaman, Al, Asayesh, Hamid, Asfaw, Ephrem Tsegay, Ashagre, Alebachew Fasil, Assadi, Reza, Ataeinia, Bahar, Atalay, Hagos Tasew, Ataro, Zerihun, Atique, Suleman, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide FGA, Awasthi, Ashish, Awoke, Nefsu, Ayala Quintanilla, Beatriz Paulina, Ayanore, Martin Amogre, Ayele, Henok Tadesse, Babaee, Ebrahim, Bacha, Umar, Badawi, Alaa, Bagherzadeh, Mojtaba, Bagli, Eleni, Balakrishnan, Senthilkuimar, Balouchi, Abbas, Bärnighausen, Till Winfried, Battista, Robert J, Behzadifar, Masoud, Behzadifar, Meysam, Bekele, Bayu Begashaw, Belay, Yared Belete, Belayneh, Yaschilal Muche, Berfield, Kathleen Kim Sachiko, Berhane, Adugnaw, Bernabe, Eduardo, Beuran, Mircea, Bhakta, Nickhill, Bhattacharyya, Krittika, Biadgo, Belete, Bijani, Ali, Bin Sayeed, Muhammad Shahdaat, Birungi, Charles, Bisignano, Catherine, Bitew, Helen, Bjørge, Tone, Bleyer, Archie, Bogale, Kassawmar Angaw, Bojia, Hunduma Amensisa, Borzì, Antonio M, Bosetti, Cristina, Bou-Orm, Ibrahim R, Brenner, Hermann, Brewer, Jerry D, Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Bustamante-Teixeira, Maria Teresa, Butt, Zahid A, Carreras, Giulia, Carrero, Juan J, Carvalho, Félix, Castro, Clara, Castro, Franz, Catalá-López, Ferrán, Cerin, Ester, Chaiah, Yazan, Chanie, Wagaye Fentahun, Chattu, Vijay Kumar, Chaturvedi, Pankaj, Chauhan, Neelima Singh, Chehrazi, Mohammad, Chiang, Peggy Pei-Chia, Chichiabellu, Tesfaye Yitna, Chido-Amajuoyi, Onyema Greg, Chimed-Ochir, Odgerel, Choi, Jee-Young J, Christopher, Devasahayam J, Chu, Dinh-Toi, Constantin, Maria-Magdalena, Costa, Vera M, Crocetti, Emanuele, Crowe, Christopher Stephen, Curado, Maria Paula, Dahlawi, Saad MA, Damiani, Giovanni, Darwish, Amira Hamed, Daryani, Ahmad, das Neves, José, Demeke, Feleke Mekonnen, Demis, Asmamaw Bizuneh, Demissie, Birhanu Wondimeneh, Demoz, Gebre Teklemariam, Denova-Gutiérrez, Edgar, Derakhshani, Afshin, Deribe, Kalkidan Solomon, Desai, Rupak, Desalegn, Beruk Berhanu, Desta, Melaku, Dey, Subhojit, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Diaz, Daniel, Dinberu, Mesfin Tadese Tadese, Djalalinia, Shirin, Doku, David Teye, Drake, Thomas M, Dubey, Manisha, Dubljanin, Eleonora, Duken, Eyasu Ejeta, Ebrahimi, Hedyeh, Effiong, Andem, Eftekhari, Aziz, El Sayed, Iman, Zaki, Maysaa El Sayed, El-Jaafary, Shaimaa I, El-Khatib, Ziad, Elemineh, Demelash Abewa, Elkout, Hajer, Ellenbogen, Richard G, Elsharkawy, Aisha, Emamian, Mohammad Hassan, Endalew, Daniel Adane, Endries, Aman Yesuf, Eshrati, Babak, Fadhil, Ibtihal, Fallah, Vahid, Faramarzi, Mahbobeh, Farhangi, Mahdieh Abbasalizad, Farioli, Andrea, Farzadfar, Farshad, Fentahun, Netsanet, Fernandes, Eduarda, Feyissa, Garumma Tolu, Filip, Irina, Fischer, Florian, Fisher, James L, Force, Lisa M, Foroutan, Masoud, Freitas, Marisa, Fukumoto, Takeshi, Futran, Neal D, Gallus, Silvano, Gankpe, Fortune Gbetoho, Gayesa, Reta Tsegaye, Gebrehiwot, Tsegaye Tewelde, Gebremeskel, Gebreamlak Gebremedhn, Gedefaw, Getnet Azeze, Gelaw, Belayneh K, Geta, Birhanu, Getachew, Sefonias, Gezae, Kebede Embaye, Ghafourifard, Mansour, Ghajar, Alireza, Ghashghaee, Ahmad, Gholamian, Asadollah, Gill, Paramjit Singh, Ginindza, Themba TG, Girmay, Alem, Gizaw, Muluken, Gomez, Ricardo Santiago, Gopalani, Sameer Vali, Gorini, Giuseppe, Goulart, Bárbara Niegia Garcia, Grada, Ayman, Ribeiro Guerra, Maximiliano, Guimaraes, Andre Luiz Sena, Gupta, Prakash C, Gupta, Rahul, Hadkhale, Kishor, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hamadeh, Randah R, Hamidi, Samer, Hanfore, Lolemo Kelbiso, Haro, Josep Maria, Hasankhani, Milad, Hasanzadeh, Amir, Hassen, Hamid Yimam, Hay, Roderick J, Hay, Simon I, Henok, Andualem, Henry, Nathaniel J, Herteliu, Claudiu, Hidru, Hagos D, Hoang, Chi Linh, Hole, Michael K, Hoogar, Praveen, Horita, Nobuyuki, Hosgood, H Dean, Hosseini, Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Hussen, Mohammedaman Mama, Ileanu, Bogdan, Ilic, Milena D, Innos, Kaire, Irvani, Seyed Sina Naghibi, Iseh, Kufre Robert, Islam, Sheikh Mohammed Shariful, Islami, Farhad, Jafari Balalami, Nader, Jafarinia, Morteza, Jahangiry, Leila, Jahani, Mohammad Ali, Jahanmehr, Nader, Jakovljevic, Mihajlo, James, Spencer L, Javanbakht, Mehdi, Jayaraman, Sudha, Jee, Sun Ha, Jenabi, Ensiyeh, Jha, Ravi Prakash, Jonas, Jost B, Jonnagaddala, Jitendra, Joo, Tamas, Jungari, Suresh Banayya, Jürisson, Mikk, Kabir, Ali, Kamangar, Farin, Karch, André, Karimi, Narges, Karimian, Ansar, Kasaeian, Amir, Kasahun, Gebremicheal Gebreslassie, Kassa, Belete, Kassa, Tesfaye Dessale, Kassaw, Mesfin Wudu, Kaul, Anil, Keiyoro, Peter Njenga, Kelbore, Abraham Getachew, Kerbo, Amene Abebe, Khader, Yousef Saleh, Khalilarjmandi, Maryam, Khan, Ejaz Ahmad, Khan, Gulfaraz, Khang, Young-Ho, Khatab, Khaled, Khater, Amir, Khayamzadeh, Maryam, Khazaee-Pool, Maryam, Khazaei, Salman, Khoja, Abdullah T, Khosravi, Mohammad Hossein, Khubchandani, Jagdish, Kianipour, Neda, Kim, Daniel, Kim, Yun Jin, Kisa, Adnan, Kisa, Sezer, Kissimova-Skarbek, Katarzyna, Komaki, Hamidreza, Koyanagi, Ai, Krohn, Kristopher J, Bicer, Burcu Kucuk, Kugbey, Nuworza, Kumar, Vivek, Kuupiel, Desmond, La Vecchia, Carlo, Lad, Deepesh P, Lake, Eyasu Alem, Lakew, Ayenew Molla, Lal, Dharmesh Kumar, Lami, Faris Hasan, Lan, Qing, Lasrado, Savita, Lauriola, Paolo, Lazarus, Jeffrey V, Leigh, James, Leshargie, Cheru Tesema, Liao, Yu, Limenih, Miteku Andualem, Listl, Stefan, Lopez, Alan D, Lopukhov, Platon D, Lunevicius, Raimundas, Madadin, Mohammed, Magdeldin, Sameh, El Razek, Hassan Magdy Abd, Majeed, Azeem, Maleki, Afshin, Malekzadeh, Reza, Manafi, Ali, Manafi, Navid, Manamo, Wondimu Ayele, Mansourian, Morteza, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Maroufizadeh, Saman, Martini, Santi Martini S, Mashamba-Thompson, Tivani Phosa, Massenburg, Benjamin Ballard, Maswabi, Motswadi Titus, Mathur, Manu Raj, McAlinden, Colm, McKee, Martin, Meheretu, Hailemariam Abiy Alemu, Mehrotra, Ravi, Mehta, Varshil, Meier, Toni, Melaku, Yohannes A, Meles, Gebrekiros Gebremichael, Meles, Hagazi Gebre, Melese, Addisu, Melku, Mulugeta, Memiah, Peter TN, Mendoza, Walter, Menezes, Ritesh G, Merat, Shahin, Meretoja, Tuomo J, Mestrovic, Tomislav, Miazgowski, Bartosz, Miazgowski, Tomasz, Mihretie, Kebadnew Mulatu M, Miller, Ted R, Mills, Edward J, Mir, Seyed Mostafa, Mirzaei, Hamed, Mirzaei, Hamid Reza, Mishra, Rashmi, Moazen, Babak, Mohammad, Dara K, Mohammad, Karzan Abdulmuhsin, Mohammad, Yousef, Darwesh, Aso Mohammad, Mohammadbeigi, Abolfazl, Mohammadi, Hiwa, Mohammadi, Moslem, Mohammadian, Mahdi, Mohammadian-Hafshejani, Abdollah, Mohammadoo-Khorasani, Milad, Mohammadpourhodki, Reza, Mohammed, Ammas Siraj, Mohammed, Jemal Abdu, Mohammed, Shafiu, Mohebi, Farnam, Mokdad, Ali H, Monasta, Lorenzo, Moodley, Yoshan, Moosazadeh, Mahmood, Moossavi, Maryam, Moradi, Ghobad, Moradi-Joo, Mohammad, Moradi-Lakeh, Maziar, Moradpour, Farhad, Morawska, Lidia, Morgado-da-Costa, Joana, Morisaki, Naho, Morrison, Shane Douglas, Mosapour, Abbas, Mousavi, Seyyed Meysam, Muche, Achenef Asmamaw, Muhammed, Oumer Sada S, Musa, Jonah, Nabhan, Ashraf R, Naderi, Mehdi, Nagarajan, Ahamarshan Jayaraman, Nagel, Gabriele, Nahvijou, Azin, Naik, Gurudatta, Najafi, Farid, Naldi, Luigi, Nam, Hae Sung, Nasiri, Naser, Nazari, Javad, Negoi, Ionut, Neupane, Subas, Newcomb, Polly A, Nggada, Haruna Asura, Ngunjiri, Josephine W, Nguyen, Cuong Tat, Nikniaz, Leila, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Nixon, Molly R, Nnaji, Chukwudi A, Nojomi, Marzieh, Nosratnejad, Shirin, Shiadeh, Malihe Nourollahpour, Obsa, Mohammed Suleiman, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Olagunju, Andrew T, Olagunju, Tinuke O, Oluwasanu, Mojisola Morenike, Omonisi, Abidemi E, Onwujekwe, Obinna E, Oommen, Anu Mary, Oren, Eyal, Ortega-Altamirano, Doris DV, Ota, Erika, Otstavnov, Stanislav S, Owolabi, Mayowa Ojo, P A, Mahesh, Padubidri, Jagadish Rao, Pakhale, Smita, Pakpour, Amir H, Pana, Adrian, Park, Eun-Kee, Parsian, Hadi, Pashaei, Tahereh, Patel, Shanti, Patil, Snehal T, Pennini, Alyssa, Pereira, David M, Piccinelli, Cristiano, Pillay, Julian David, Pirestani, Majid, Pishgar, Farhad, Postma, Maarten J, Pourjafar, Hadi, Pourmalek, Farshad, Pourshams, Akram, Prakash, Swayam, Prasad, Narayan, Qorbani, Mostafa, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Rafiei, Alireza, Rahim, Fakher, Rahimi, Mahdi, Rahman, Muhammad Aziz, Rajati, Fatemeh, Rana, Saleem M, Raoofi, Samira, Rath, Goura Kishor, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C, Renzaho, Andre MN, Rezaei, Nima, Rezapour, Aziz, Ribeiro, Ana Isabel, Ribeiro, Daniela, Ronfani, Luca, Roro, Elias Merdassa, Roshandel, Gholamreza, Rostami, Ali, Saad, Ragy Safwat, Sabbagh, Parisa, Sabour, Siamak, Saddik, Basema, Safiri, Saeid, Sahebkar, Amirhossein, Salahshoor, Mohammad Reza, Salehi, Farkhonde, Salem, Hosni, Salem, Marwa Rashad, Salimzadeh, Hamideh, Salomon, Joshua A, Samy, Abdallah M, Sanabria, Juan, Santric Milicevic, Milena M, Sartorius, Benn, Sarveazad, Arash, Sathian, Brijesh, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Sayyah, Mehdi, Schneider, Ione JC, Schöttker, Ben, Sekerija, Mario, Sepanlou, Sadaf G, Sepehrimanesh, Masood, Seyedmousavi, Seyedmojtaba, Shaahmadi, Faramarz, Shabaninejad, Hosein, Shahbaz, Mohammad, Shaikh, Masood Ali, Shamshirian, Amir, Shamsizadeh, Morteza, Sharafi, Heidar, Sharafi, Zeinab, Sharif, Mehdi, Sharifi, Ali, Sharifi, Hamid, Sharma, Rajesh, Sheikh, Aziz, Shirkoohi, Reza, Shukla, Sharvari Rahul, Si, Si, Siabani, Soraya, Silva, Diego Augusto Santos, Silveira, Dayane Gabriele Alves, Singh, Ambrish, Singh, Jasvinder A, Sisay, Solomon, Sitas, Freddy, Sobngwi, Eugène, Soofi, Moslem, Soriano, Joan B, Stathopoulou, Vasiliki, Sufiyan, Mu’awiyyah Babale, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Takahashi, Ken, Tamtaji, Omid Reza, Tarawneh, Mohammed Rasoul, Tassew, Segen Gebremeskel, Taymoori, Parvaneh, Tehrani-Banihashemi, Arash, Temsah, Mohamad-Hani, Temsah, Omar, Tesfay, Berhe Etsay, Tesfay, Fisaha Haile, Teshale, Manaye Yihune, Tessema, Gizachew Assefa, Thapa, Subash, Tlaye, Kenean Getaneh, Topor-Madry, Roman, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Bach Xuan, Tran, Khanh Bao, Tsadik, Afewerki Gebremeskel, Ullah, Irfan, Uthman, Olalekan A, Vacante, Marco, Vaezi, Maryam, Varona Pérez, Patricia, Veisani, Yousef, Vidale, Simone, Violante, Francesco S, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Vosoughi, Kia, Vu, Giang Thu, Vujcic, Isidora S, Wabinga, Henry, Wachamo, Tesfahun Mulatu, Wagnew, Fasil Shiferaw, Waheed, Yasir, Weldegebreal, Fitsum, Weldesamuel, Girmay Teklay, Wijeratne, Tissa, Wondafrash, Dawit Zewdu, Wonde, Tewodros Eshete, Wondmieneh, Adam Belay, Workie, Hailemariam Mekonnen, Yadav, Rajaram, Yadegar, Abbas, Yadollahpour, Ali, Yaseri, Mehdi, Yazdi-Feyzabadi, Vahid, Yeshaneh, Alex, Yimam, Mohammed Ahmed, Yimer, Ebrahim M, Yisma, Engida, Yonemoto, Naohiro, Younis, Mustafa Z, Yousefi, Bahman, Yousefifard, Mahmoud, Yu, Chuanhua, Zabeh, Erfan, Zadnik, Vesna, Moghadam, Telma Zahirian, Zaidi, Zoubida, Zamani, Mohammad, Zandian, Hamed, Zangeneh, Alireza, Zaki, Leila, Zendehdel, Kazem, Zenebe, Zerihun Menlkalew, Zewale, Taye Abuhay, Ziapour, Arash, Zodpey, Sanjay, and Murray, Christopher JL
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Global Burden of Disease Cancer Collaboration - Abstract
Importance Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data.\ud \ud Objective To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning.\ud \ud Evidence Review We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence.\ud \ud Findings In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572 000 deaths and 15.2 million DALYs), and stomach cancer (542 000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819 000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601 000 deaths and 17.4 million DALYs), TBL cancer (596 000 deaths and 12.6 million DALYs), and colorectal cancer (414 000 deaths and 8.3 million DALYs).\ud \ud Conclusions and Relevance The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer
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- 2019
16. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016
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Troeger, Christopher, Blacker, Brigette F, Khalil, Ibrahim A, Rao, Puja C, Cao, Shujin, Zimsen, Stephanie RM, Albertson, Samuel B, Stanaway, Jeffery D, Deshpande, Aniruddha, Abebe, Zegeye, Alvis-Guzman, Nelson, Amare, Azmeraw T, Asgedom, Solomon W, Anteneh, Zelalem Alamrew, Antonio, Carl Abelardo T, Aremu, Olatunde, Asfaw, Ephrem Tsegay, Atey, Tesfay Mehari, Atique, Suleman, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Ayele, Henok Tadesse, Barac, Aleksandra, Barreto, Mauricio L, Bassat, Quique, Belay, Saba Abraham, Bensenor, Isabela M, Bhutta, Zulfiqar A, Bijani, Ali, Bizuneh, Hailemichael, Castañeda-Orjuela, Carlos A, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Do, Huyen Phuc, Dubey, Manisha, Dubljanin, Eleonora, Edessa, Dumessa, Endries, Aman Yesuf, Eshrati, Babak, Farag, Tamer, Feyissa, Garumma Tolu, Foreman, Kyle J, Forouzanfar, Mohammad H, Fullman, Nancy, Gething, Peter W, Gishu, Melkamu Dedefo, Godwin, William W, Gugnani, Harish Chander, Gupta, Rahul, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hibstu, Desalegn Tsegaw, Ilesanmi, Olayinka S, Jonas, Jost B, Kahsay, Amaha, Kang, Gagandeep, Kasaeian, Amir, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Muhammad Ali, Khang, Young-Ho, Kissoon, Niranjan, Kochhar, Sonali, Kotloff, Karen L, Koyanagi, Ai, Kumar, G Anil, Magdy Abd El Razek, Hassan, Malekzadeh, Reza, Malta, Deborah Carvalho, Mehata, Suresh, Mendoza, Walter, Mengistu, Desalegn Tadese, Menota, Bereket Gebremichael, Mezgebe, Haftay Berhane, Mlashu, Fitsum Weldegebreal, Murthy, Srinivas, Naik, Gurudatta A, Nguyen, Cuong Tat, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Ogbo, Felix Akpojene, Olagunju, Andrew Toyin, Paudel, Deepak, Platts-Mills, James A, Qorbani, Mostafa, Rafay, Anwar, Rai, Rajesh Kumar, Rana, Saleem M, Ranabhat, Chhabi Lal, Rasella, Davide, Ray, Sarah E, Reis, Cesar, Renzaho, Andre MN, Rezai, Mohammad Sadegh, Ruhago, George Mugambage, Safiri, Saeid, Salomon, Joshua A, Sanabria, Juan Ramon, Sartorius, Benn, Sawhney, Monika, Sepanlou, Sadaf G, Shigematsu, Mika, Sisay, Mekonnen, Somayaji, Ranjani, Sreeramareddy, Chandrashekhar T, Sykes, Bryan L, Taffere, Getachew Redae, Topor-Madry, Roman, Tran, Bach Xuan, Tuem, Kald Beshir, Ukwaja, Kingsley Nnanna, Vollset, Stein Emil, Walson, Judd L, Weaver, Marcia R, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Workicho, Abdulhalik, Yenesew, Muluken, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, El Sayed Zaki, Maysaa, Vos, Theo, Lim, Stephen S, Naghavi, Mohsen, Murray, Christopher JL, Mokdad, Ali H, Hay, Simon I, and Reiner, Robert C
- Abstract
Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 provides an up-to-date analysis of the burden of diarrhoea in 195 countries. This study assesses cases, deaths, and aetiologies in 1990–2016 and assesses how the burden of diarrhoea has changed in people of all ages Methods We modelled diarrhoea mortality with a Bayesian hierarchical modelling platform that evaluates a wide range of covariates and model types on the basis of vital registration and verbal autopsy data. We modelled diarrhoea incidence with a compartmental meta-regression tool that enforces an association between incidence and prevalence, and relies on scientific literature, population representative surveys, and health-care data. Diarrhoea deaths and episodes were attributed to 13 pathogens by use of a counterfactual population attributable fraction approach. Diarrhoea risk factors are also based on counterfactual estimates of risk exposure and the association between the risk and diarrhoea. Each modelled estimate accounted for uncertainty. Findings In 2016, diarrhoea was the eighth leading cause of death among all ages (1 655 944 deaths, 95% uncertainty interval [UI] 1 244 073–2 366 552) and the fifth leading cause of death among children younger than 5 years (446 000 deaths, 390 894–504 613). Rotavirus was the leading aetiology for diarrhoea mortality among children younger than 5 years (128 515 deaths, 105 138–155 133) and among all ages (228 047 deaths, 183 526–292 737). Childhood wasting (low weight-for-height score), unsafe water, and unsafe sanitation were the leading risk factors for diarrhoea, responsible for 80·4% (95% UI 68·2–85·0), 72·1% (34·0–91·4), and 56·4% (49·3–62·7) of diarrhoea deaths in children younger than 5 years, respectively. Prevention of wasting in 1762 children (95% UI 1521–2170) could avert one death from diarrhoea. Interpretation Substantial progress has been made globally in reducing the burden of diarrhoeal diseases, driven by decreases in several primary risk factors. However, this reduction has not been equal across locations, and burden among adults older than 70 years requires attention.
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- 2019
17. Carga mundial, regional y nacional de la tuberculosis, 1990-2016: resultados de la carga mundial de enfermedades, Estudio de Lesiones y Factores de Riesgo 2016
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HH, Kyu, ER, Maddison, NJ, Henry, JR, Ledesma, KE, Wiens, Jr R, Reiner, Molly H, Biehl, Shields, Chloe, Osgood-Zimmerman, Aaron, Ross, Jennifer M, Carter, Austin, Tahvi D, Frank, Haidong, Wang, Srinivasan, Vinay, Sanjay Kumar, Agarwal, Fares, Alahdab, Kefyalew Addis, Alene, Beriwan Abdulqadir, Ali, Alvis-Guzman, Nelson, Andrews, Jason R, Antonio T, Carl Abelardo, Atique, Suleman, Atre, Sachin R, Awasthi, Ashish, Ayele, Henok Tadesse, Badali, Hamid, Badawi, Alaa, Barac, Aleksandra, Bedi, Neeraj, Behzadifar, Masoud, Behzadifar, Meysam, Bekele, Bayu Begashaw, Belay, Saba Abraham, Bensenor, Isabela M, Butt, Zahid A, Carvalho, Félix, Cercy, Kelly, Christopher, Devasahayam J, Daba, Alemneh Kabeta, Dandona, Lalit, Dandona, Rakhi, Daryani, Ahmad, Demeke, Feleke Mekonnen, Deribe, Kebede, Dharmaratne, Samath Dhamminda, Doku, David Teye, Dubey, Manisha, Edessa, Dumessa, El-Khatib, Ziad, Enany, Shymaa, Fernandes, Eduarda, Fischer, Florian, Garcia-Basteiro, Alberto L, Gebre, Abadi Kahsu, Gebregergs, Gebremedhin Berhe, Gebremichael, Teklu Gebrehiwo, Gelano, Tilayie Feto, Geremew, Demeke, Gona, Philimon N, Goodridge, Amador, Gupta, Rahul, Haghparast Bidgoli, Hassan, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hedayati Tadesse, Mohammad T., Henok, Andualem, Hostiuc, Sorin, Hussen, Mamusha Aman, Ilesanmi, Olayinka Stephen, Irvani Naghibi, Seyed Sina, Jacobsen, Kathryn H, Johnson, Sarah C, Jonas, Jost B., Kahsay, Amaha, Kant, Surya, Kasaeian, Amir, Kassa, Tesfaye Dessale, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khalil, Ibrahim, Khan, Ejaz Ahmad, Khang, Young-Ho, Kim, Yun Jin, Kochhar, Sonali, Koyanagi, Ai, Krohn, Kristopher J, Kumar, G Anil, Lakew, Ayenew Molla, Leshargie, Cheru Tesema, Lodha, Rakesh, Macarayan King, Erlyn Rachelle, Majdzadeh, Reza, Martins-Melo, Francisco Rogerlândio, Melese, Addisu, Memish, Ziad A, Mendoza, Walter, Mengistu, Desalegn Tadese, Mengistu, Getnet, Mestrovic, Tomislav, Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammed, Shafiu, Mokdad, Ali H, Moosazadeh, Mahmood, Mousavi, Seyyed Meysam, Mustafa, Ghulam, Nachega, Jean B, Nguyen, Long Hoang, Nguyen, Son Hoang, Nguyen, Trang Huyen, Ningrum Anggraini, Dina Nur, Nirayo, Yirga Legesse, Nong, Vuong Minh, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T, Oren, Eyal, Pereira, David M., Prakash, Swayam, Qorbani, Mostafa, Rafay, Anwar, Rai, Rajesh Kumar, Ram, Usha, Rubino, Salvatore, Safiri, Saeid, Salomon, Joshua A, Samy, Abdallah M., Sartorius, Benn, Satpathy, Maheswar, Seyedmousavi, Seyedmojtaba, Sharif, Mehdi, Silva, João Pedro, Silveira Alves, Dayane Gabriele, Singh, Jasvinder A, Sreeramareddy, Chandrashekhar T, Tran, Bach Xuan, Tsadik, Afewerki Gebremeskel, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Uthman, Olalekan A, Vlassov, Vasily, Vollset, Stein Emil, Vu, Giang, Weldegebreal, Fitsum, Werdecker, Andrea, Yimer, Ebrahim M, Yonemoto, Naohiro, Yotebieng, Marcel, Naghavi, Mohsen, Vos, Theo, Hay, Simon I, and Murray L, Christopher J
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Preventable and treatable disease ,Sustainable Development Goals ,Tuberculosis ,Objetivos de Desarrollo Sostenible ,Enfermedad prevenible y tratable - Abstract
Background Although a preventable and treatable disease, tuberculosis causes more than a million deaths each year. As countries work towards achieving the Sustainable Development Goal (SDG) target to end the tuberculosis epidemic by 2030, robust assessments of the levels and trends of the burden of tuberculosis are crucial to inform policy and programme decision making. We assessed the levels and trends in the fatal and non-fatal burden of tuberculosis by drug resistance and HIV status for 195 countries and territories from 1990 to 2016. Antecedentes Aunque es una enfermedad prevenible y tratable, la tuberculosis causa más de un millón de muertes cada año. A medida que los países trabajan para alcanzar la meta de los Objetivos de Desarrollo Sostenible (ODS) de terminar con la epidemia de tuberculosis para 2030, las evaluaciones sólidas de los niveles y tendencias de la carga de la tuberculosis son cruciales para informar la toma de decisiones de políticas y programas. Evaluamos los niveles y las tendencias en la carga mortal y no mortal de la tuberculosis por la resistencia a los medicamentos y el estado del VIH en 195 países y territorios desde 1990 hasta 2016.
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- 2018
18. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016
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Fullman, Nancy, Yearwood, Jamal, Abay, Solomon M., Abbafati, Cristiana, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abebe, Zegeye, Abebo, Teshome Abuka, Aboyans, Victor, Abraha, Haftom Niguse, Abreu, Daisy M. X., Abu-Raddad, Laith J., Adane, Akilew Awoke, Adedoyin, Rufus Adesoji, Adetokunboh, Olatunji, Adhikari, Tara Ballav, Afarideh, Mohsen, Afshin, Ashkan, Agarwal, Gina, Agius, Dominic, Agrawal, Anurag, Agrawal, Sutapa, Kiadaliri, Aliasghar Ahmad, Aichour, Miloud Taki Eddine, Akibu, Mohammed, Akinyemi, Rufus Olusola, Akinyemiju, Tomi F., Akseer, Nadia, Al Lami, Faris Hasan, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Tahiya, Alasfoor, Deena, Albittar, Mohammed I., Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed M., Alkerwi, Ala'a, Alla, Francois, Allebeck, Peter, Allen, Christine, Alomari, Mahmoud A., Al-Raddadi, Rajaa, Alsharif, Ubai, Altirkawi, Khalid A., Alvis-Guzman, Nelson, Amare, Azmeraw T., Amenu, Kebede, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla, Andrei, Catalina Liliana, Androudi, Sofia, Antonio, Carl Abelardo T., Araujo, Valdelaine E. M., Aremu, Olatunde, Arnlöv, Johan, Artaman, Al, Aryal, Krishna Kumar, Asayesh, Hamid, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Asghar, Rana Jawad, Ashebir, Mengistu Mitiku, Asseffa, Netsanet Abera, Atey, Tesfay Mehari, Atre, Sachin R., Atteraya, Madhu S., Avila-Burgos, Leticia, Avokpaho, Euripide Frinel G. Arthur, Awasthi, Ashish, Quintanilla, Beatriz Paulina Ayala, Ayalew, Animut Alebel, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe Betrand, Azzopardi, Peter, Azzopardi-Muscat, Natasha, Babalola, Tesleem Kayode, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Banerjee, Amitava, Banstola, Amrit, Barber, Ryan M., Barboza, Miguel A., Barker-Collo, Suzanne L., Bärnighausen, Till, Barquera, Simon, Barrero, Lope H., Bassat, Quique, Basu, Sanjay, Baune, Bernhard T., Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Meysam, Htet, Aung Soe, Kisa, Adnan, Norheim, Ole Frithjof, Savic, Miloje, Skirbekk, Vegard Fykse, Vollset, Stein Emil, Weiderpass, Elisabete, and Winkler, Andrea Sylvia
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Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016. Methods Drawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0–100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best); we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0–100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derived from the broader GBD study and other data sources, we examined relationships between national HAQ Index scores and potential correlates of performance, such as total health spending per capita. Findings In 2016, HAQ Index performance spanned from a high of 97·1 (95% UI 95·8–98·1) in Iceland, followed by 96·6 (94·9–97·9) in Norway and 96·1 (94·5–97·3) in the Netherlands, to values as low as 18·6 (13·1–24·4) in the Central African Republic, 19·0 (14·3–23·7) in Somalia, and 23·4 (20·2–26·8) in Guinea-Bissau. The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. Striking subnational disparities emerged in personal health-care access and quality, with China and India having particularly large gaps between locations with the highest and lowest scores in 2016. In China, performance ranged from 91·5 (89·1–93·6) in Beijing to 48·0 (43·4–53·2) in Tibet (a 43·5-point difference), while India saw a 30·8-point disparity, from 64·8 (59·6–68·8) in Goa to 34·0 (30·3–38·1) in Assam. Japan recorded the smallest range in subnational HAQ performance in 2016 (a 4·8-point difference), whereas differences between subnational locations with the highest and lowest HAQ Index values were more than two times as high for the USA and three times as high for England. State-level gaps in the HAQ Index in Mexico somewhat narrowed from 1990 to 2016 (from a 20·9-point to 17·0-point difference), whereas in Brazil, disparities slightly increased across states during this time (a 17·2-point to 20·4-point difference). Performance on the HAQ Index showed strong linkages to overall development, with high and high-middle SDI countries generally having higher scores and faster gains for non-communicable diseases. Nonetheless, countries across the development spectrum saw substantial gains in some key health service areas from 2000 to 2016, most notably vaccine-preventable diseases. Overall, national performance on the HAQ Index was positively associated with higher levels of total health spending per capita, as well as health systems inputs, but these relationships were quite heterogeneous, particularly among low-to-middle SDI countries. Interpretation GBD 2016 provides a more detailed understanding of past success and current challenges in improving personal health-care access and quality worldwide. Despite substantial gains since 2000, many low-SDI and middle-SDI countries face considerable challenges unless heightened policy action and investments focus on advancing access to and quality of health care across key health services, especially non-communicable diseases. Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. Alongside initiatives to strengthen public health programmes, the pursuit of universal health coverage hinges upon improving both access and quality worldwide, and thus requires adopting a more comprehensive view—and subsequent provision—of quality health care for all populations. publishedVersion
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- 2018
19. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017
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Dicker, D, Nguyen, G, Abate, D, Abate, K, Abay, S, Abbafati, C, Abbasi, N, Abbastabar, H, Abd-Allah, F, Abdela, J, Abdelalim, A, Abdel-Rahman, O, Abdi, A, Abdollahpour, I, Abdulkader, R, Abdurahman, A, Abebe, H, Abebe, M, Abebe, Z, Abebo, T, Aboyans, V, Abraha, H, Abrham, A, Abu-Raddad, L, Abu-Rmeileh, N, Accrombessi, M, Acharya, P, Adebayo, O, Adedeji, I, Adedoyin, R, Adekanmbi, V, Adetokunboh, O, Adhena, B, Adhikari, T, Adib, M, Adou, A, Adsuar, J, Afarideh, M, Afshin, A, Agarwal, G, Aggarwal, R, Aghayan, S, Agrawal, S, Agrawal, A, Ahmadi, M, Ahmadi, A, Ahmadieh, H, Ahmed, M, Ahmed, S, Aichour, A, Aichour, I, Aichour, M, Akanda, A, Akbari, M, Akibu, M, Akinyemi, R, Akinyemiju, T, Akseer, N, Alahdab, F, Al-Aly, Z, Alam, K, Alebel, A, Aleman, A, Alene, K, Al-Eyadhy, A, Ali, R, Alijanzadeh, M, Alizadeh-Navaei, R, Aljunid, S, Alkerwi, A, Alla, F, Allebeck, P, Allen, C, Alonso, J, Al-Raddadi, R, Alsharif, U, Altirkawi, K, Alvis-Guzman, N, Amare, A, Amini, E, Ammar, W, Amoako, Y, Anber, N, Andrei, C, Androudi, S, Animut, M, Anjomshoa, M, Anlay, D, Ansari, H, Ansariadi, A, Ansha, M, Antonio, C, Appiah, S, Aremu, O, Areri, H, Ärnlöv, J, Arora, M, Artaman, A, Aryal, K, Asadi-Lari, M, Asayesh, H, Asfaw, E, Asgedom, S, Assadi, R, Ataro, Z, Atey, T, Athari, S, Atique, S, Atre, S, Atteraya, M, Attia, E, Ausloos, M, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Awuah, B, Ayala Quintanilla, B, Ayele, H, Ayele, Y, Ayer, R, Ayuk, T, Azzopardi, P, Azzopardi-Muscat, N, Badali, H, Badawi, A, Balakrishnan, K, Bali, A, Banach, M, Banstola, A, Barac, A, Barboza, M, Barquera, S, Barrero, L, Basaleem, H, Bassat, Q, Basu, A, Basu, S, Baune, B, Bazargan-Hejazi, S, Bedi, N, Beghi, E, Behzadifar, M, Béjot, Y, Bekele, B, Belachew, A, Belay, A, Belay, E, Belay, S, Belay, Y, Bell, M, Bello, A, Bennett, D, Bensenor, I, Berhane, A, Berman, A, Bernabe, E, Bernstein, R, Bertolacci, G, Beuran, M, Beyranvand, T, Bhala, N, Bhatia, E, Bhatt, S, Bhattarai, S, Bhaumik, S, Bhutta, Z, Biadgo, B, Bijani, A, Bikbov, B, Bililign, N, Bin Sayeed, M, Birlik, S, Birungi, C, Bisanzio, D, Biswas, T, Bjørge, T, Bleyer, A, Basara, B, Bose, D, Bosetti, C, Boufous, S, Bourne, R, Brady, O, Bragazzi, N, Brant, L, Brazinova, A, Breitborde, N, Brenner, H, Britton, G, Brugha, T, Burke, K, Busse, R, Butt, Z, Cahuana-Hurtado, L, Callender, C, Campos-Nonato, I, Campuzano Rincon, J, Cano, J, Car, M, Cárdenas, R, Carreras, G, Carrero, J, Carter, A, Carvalho, F, Castañeda-Orjuela, C, Castillo Rivas, J, Castro, F, Catalá-López, F, Çavlin, A, Cerin, E, Chaiah, Y, Champs, A, Chang, H, Chang, J, Chattopadhyay, A, Chaturvedi, P, Chen, W, Chiang, P, Chimed-Ochir, O, Chin, K, Chisumpa, V, Chitheer, A, Choi, J, Christensen, H, Christopher, D, Chung, S, Cicuttini, F, Ciobanu, L, Cirillo, M, Claro, R, Cohen, A, Collado-Mateo, D, Constantin, M, Conti, S, Cooper, C, Cooper, L, Cortesi, P, Cortinovis, M, Cousin, E, Criqui, M, Cromwell, E, Crowe, C, Crump, J, Cucu, A, Cunningham, M, Daba, A, Dachew, B, Dadi, A, Dandona, L, Dandona, R, Dang, A, Dargan, P, Daryani, A, Das, S, Das Gupta, R, das Neves, J, Dasa, T, Dash, A, Weaver, N, Davitoiu, D, Davletov, K, Dayama, A, Courten, B, De la Hoz, F, De leo, D, De Neve, J, Degefa, M, Degenhardt, L, Degfie, T, Deiparine, S, Dellavalle, R, Demoz, G, Demtsu, B, Denova-Gutiérrez, E, Deribe, K, Dervenis, N, Des Jarlais, D, Dessie, G, Dey, S, Dharmaratne, S, Dhimal, M, Ding, E, Djalalinia, S, Doku, D, Dolan, K, Donnelly, C, Dorsey, E, Douwes-Schultz, D, Doyle, K, Drake, T, Driscoll, T, Dubey, M, Dubljanin, E, Duken, E, Duncan, B, Duraes, A, Ebrahimi, H, Ebrahimpour, S, Edessa, D, Edvardsson, D, Eggen, A, El Bcheraoui, C, El Sayed Zaki, M, Elfaramawi, M, El-Khatib, Z, Ellingsen, C, Elyazar, I, Enayati, A, Endries, A, Er, B, Ermakov, S, Eshrati, B, Eskandarieh, S, Esmaeili, R, Esteghamati, A, Esteghamati, S, Fakhar, M, Fakhim, H, Farag, T, Faramarzi, M, Fareed, M, Farhadi, F, Farid, T, Farinha, C, Farioli, A, Faro, A, Farvid, M, Farzadfar, F, Farzaei, M, Fazeli, M, Feigin, V, Feigl, A, Feizy, F, Fentahun, N, Fereshtehnejad, S, Fernandes, E, Fernandes, J, Feyissa, G, Fijabi, D, Filip, I, Finegold, S, Fischer, F, Flor, L, Foigt, N, Ford, J, Foreman, K, Fornari, C, Frank, T, Franklin, R, Fukumoto, T, Fuller, J, Fullman, N, Fürst, T, Furtado, J, Futran, N, Galan, A, Gallus, S, Gambashidze, K, Gamkrelidze, A, Gankpe, F, Garcia-Basteiro, A, Garcia-Gordillo, M, Gebre, T, Gebre, A, Gebregergs, G, Gebrehiwot, T, Gebremedhin, A, Gelano, T, Gelaw, Y, Geleijnse, J, Genova-Maleras, R, Gessner, B, Getachew, S, Gething, P, Gezae, K, Ghadami, M, Ghadimi, R, Ghasemi Falavarjani, K, Ghasemi-Kasman, M, Ghiasvand, H, Ghimire, M, Ghoshal, A, Gill, P, Gill, T, Gillum, R, Giussani, G, Goenka, S, Goli, S, Gomez, R, Gomez-Cabrera, M, Gómez-Dantés, H, Gona, P, Goodridge, A, Gopalani, S, Goto, A, Goulart, A, Goulart, B, Grada, A, Grosso, G, Gugnani, H, Guimaraes, A, Guo, Y, Gupta, P, Gupta, R, Gupta, T, Gyawali, B, Haagsma, J, Hachinski, V, Hafezi-Nejad, N, Hagos, T, Hailegiyorgis, T, Hailu, G, Haj-Mirzaian, A, Hamadeh, R, Hamidi, S, Handal, A, Hankey, G, Harb, H, Harikrishnan, S, Haririan, H, Haro, J, Hasan, M, Hassankhani, H, Hassen, H, Havmoeller, R, Hay, R, Hay, S, He, Y, Hedayatizadeh-Omran, A, Hegazy, M, Heibati, B, Heidari, M, Hendrie, D, Henok, A, Henry, N, Heredia-Pi, I, Herteliu, C, Heydarpour, F, Heydarpour, P, Heydarpour, S, Hibstu, D, Hoek, H, Hole, M, Homaie Rad, E, Hoogar, P, Horino, M, Hosgood, H, Hosseini, S, Hosseinzadeh, M, Hostiuc, S, Hostiuc, M, Hotez, P, Hoy, D, Hsairi, M, Htet, A, Hu, G, Huang, J, Husseini, A, Hussen, M, Hutfless, S, Iburg, K, Igumbor, E, Ikeda, C, Ilesanmi, O, Iqbal, U, Irvani, S, Isehunwa, O, Islam, S, Islami, F, Jahangiry, L, Jahanmehr, N, Jain, R, Jain, S, Jakovljevic, M, James, S, Javanbakht, M, Jayaraman, S, Jayatilleke, A, Jee, S, Jeemon, P, Jha, R, Jha, V, Ji, J, Johnson, S, Jonas, J, Joshi, A, Jozwiak, J, Jungari, S, Jürisson, M, K, M, Kabir, Z, Kadel, R, Kahsay, A, Kahssay, M, Kalani, R, Kapil, U, Karami, M, Karami Matin, B, Karch, A, Karema, C, Karimi, N, Karimi, S, Karimi-Sari, H, Kasaeian, A, Kassa, G, Kassa, T, Kassa, Z, Kassebaum, N, Katibeh, M, Katikireddi, S, Kaul, A, Kawakami, N, Kazemeini, H, Kazemi, Z, Karyani, A, K C, P, Kebede, S, Keiyoro, P, Kemp, G, Kengne, A, Keren, A, Kereselidze, M, Khader, Y, Khafaie, M, Khajavi, A, Khalid, N, Khalil, I, Khan, E, Khan, G, Khan, M, Khang, Y, Khanna, T, Khater, M, Khatony, A, Khazaie, H, Khoja, A, Khosravi, A, Khosravi, M, Khubchandani, J, Kiadaliri, A, Kibret, G, Kim, C, Kim, D, Kim, J, Kim, Y, Kimokoti, R, Kinfu, Y, Kinra, S, Kisa, A, Kissimova-Skarbek, K, Kissoon, N, Kivimäki, M, Kleber, M, Knibbs, L, Knudsen, A, Kochhar, S, Kokubo, Y, Kolola, T, Kopec, J, Kosek, M, Kosen, S, Koul, P, Koyanagi, A, Kravchenko, M, Krishan, K, Krishnaswami, S, Kuate Defo, B, Kucuk Bicer, B, Kudom, A, Kuipers, E, Kulikoff, X, Kumar, G, Kumar, M, Kumar, P, Kumsa, F, Kutz, M, Lad, S, Lafranconi, A, Lal, D, Lalloo, R, Lam, H, Lami, F, Lan, Q, Langan, 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- Abstract
Background: Assessments of age-specifc mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Afairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Methods: The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specifc mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in diferent compon
- Published
- 2018
20. Alcohol use and burden for 195 countries and territories, 1990-2016 : a systematic analysis for the Global Burden of Disease Study 2016
- Author
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Griswold, Max G., Fullman, Nancy, Hawley, Caitlin, Arian, Nicholas, Zimsen, Stephanie R. M., Tymeson, Hayley D., Venkateswaran, Vidhya, Tapp, Austin Douglas, Forouzanfar, Mohammad H., Salama, Joseph S., Abate, Kalkidan Hassen, Abate, Degu, Abay, Solomon M., Abbafati, Cristiana, Abdulkader, Rizwan Suliankatchi, Abebe, Zegeye, Aboyans, Victor, Abrar, Mohammed Mehdi, Acharya, Pawan, Adetokunboh, Olatunji O., Adhikari, Tara Ballav, Adsuar, Jose C., Afarideh, Mohsen, Agardh, Emilie Elisabet, Agarwal, Gina, Aghayan, Sargis Aghasi, Agrawal, Sutapa, Ahmed, Muktar Beshir, Akibu, Mohammed, Akinyemiju, Tomi, Akseer, Nadia, Al Asfoor, Deena H., Al-Aly, Ziyad, Alahdab, Fares, Alam, Khurshid, Albujeer, Ammar, Alene, Kefyalew Addis, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T., Aminde, Leopold N., Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T., Aremu, Olatunde, Arnlov, Johan, Artaman, Al, Aryal, Krishna K., Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F. G. A., Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B., Azzopardi, Peter S., Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H., Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Bejot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A., Bensenor, Isabela M., Bernabe, Eduardo, Bernstein, Robert S., Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A., Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjorge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, Soufiane, Bragazzi, Nicola Luigi, Brenner, Hermann, Butt, Zahid A., Cahuana-Hurtado, Lucero, Calabria, Bianca, Campos-Nonato, Ismael R., Campuzano Rincon, Julio Cesar, Carreras, Giulia, Carrero, Juan J., Carvalho, Felix, Castaneda-Orjuela, Carlos A., Castillo Rivas, Jacqueline, Catala-Lopez, Ferran, Chang, Jung-Chen, Charlson, Fiona J., Chattopadhyay, Aparajita, Chaturvedi, Pankaj, Chowdhury, Rajiv, Christopher, Devasahayam J., Chung, Sheng-Chia, Ciobanu, Liliana G., Claro, Rafael M., Conti, Sara, Cousin, Ewerton, Criqui, Michael H., Dachew, Berihun Assefa, Dargan, Paul, I, Daryani, Ahmad, Das Neves, Jose, Davletov, Kairat, De Castro, Filipa, De Courten, Barbora, De Neve, Jan-Walter, Degenhardt, Louisa, Demoz, Gebre Teklemariam, Des Jarlais, Don C., Dey, Subhojit, Dhaliwal, Rupinder Singh, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Doku, David Teye, Doyle, Kerrie E., Dubey, Manisha, Dubljanin, Eleonora, Duncan, Bruce B., Ebrahimi, Hedyeh, Edessa, Dumessa, Zaki, Maysaa El Sayed, Ermakov, Sergei Petrovich, Erskine, Holly E., Esteghamati, Alireza, Faramarzi, Mahbobeh, Farioli, Andrea, Faro, Andre, Farvid, Maryam S., Farzadfar, Farshad, Feigin, Valery L., Felisbino-Mendes, Mariana Santos, Fernandes, Eduarda, Ferrari, Alize J., Ferri, Cleusa P., Fijabi, Daniel Obadare, Filip, Irina, Finger, Jonas David, Fischer, Florian, Flaxman, Abraham D., Franklin, Richard Charles, Futran, Neal D., Gallus, Silvano, Ganji, Morsaleh, Gankpe, Fortune Gbetoho, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M., Ghadimi, Reza, Ghandour, Lilian A., Ghimire, Mamata, Gill, Paramjit Singh, Ginawi, Ibrahim Abdelmageed, Giref, Ababi Zergaw Z., Gona, Philimon N., Gopalani, Sameer Vali, Gotay, Carolyn C., Goulart, Alessandra C., Greaves, Felix, Grosso, Giuseppe, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Alma Gutierrez, Reyna, Gvs, Murthy, Hafezi-Nejad, Nima, Hagos, Tekleberhan Beyene, Hailu, Gessessew Bugssa, Hamadeh, Randah R., Hamidi, Samer, Hankey, Graeme J., Harb, Hilda L., Harikrishnan, Sivadasanpillai, Maria Haro, Josep, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hay, Simon, I, Heibati, Behzad, Henok, Andualem, Heredia-Pi, Ileana, Francisco Hernandez-Llanes, Norberto, Herteliu, Claudiu, Hibstu, Desalegn Ts Tsegaw, Hoogar, Praveen, Horita, Nobuyuki, Hosgood, H. Dean, Hosseini, Mostafa, Hostiuc, Mihaela, Hu, Guoqing, Huang, Hsiang, Husseini, Abdullatif, Idrisov, Bulat, Ileanu, Bogdan Vasile, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Jackson, Maria D., Jakovljevic, Mihajlo, Jayatilleke, Achala Upendra, Jha, Ravi Prakash, Jonas, Jost B., Jozwiak, Jacek Jerzy, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kapil, Umesh, Kasaeian, Amir, Kassa, Tesfaye D. Dessale, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Kebede, Seifu, Kefale, Adane Teshome, Keiyoro, Peter Njenga, Kengne, Andre Pascal, Khader, Yousef, Khafaie, Morteza Abdullatif, Khalil, Ibrahim A., Khan, Md Nuruzzaman, Khang, Young-Ho, Khater, Mona M., Khubchandani, Jagdish, Kim, Cho-Il, Kim, Daniel, Kim, Yun Jin, Kimokoti, Ruth W., Kisa, Adnan, Kivimaki, Mika, Kochhar, Sonali, Kosen, Soewarta, Koul, Parvaiz A., Koyanagi, Ai, Krishan, Kewal, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kulkarni, Veena S., Kumar, Pushpendra, Lafranconi, Alessandra, Balaji, Arjun Lakshmana, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lami, Faris Hasan, Lan, Qing, Lang, Justin J., Lansky, Sonia, Larsson, Anders O., Latifi, Arman, Leasher, Janet L., Lee, Paul H., Leigh, James, Leinsalu, Mall, Leung, Janni, Levi, Miriam, Li, Yichong, Lim, Lee-Ling, Linn, Shai, Liu, Shiwei, Lobato-Cordero, Andrea, Lotufo, Paulo A., King Macarayan, Erlyn Rachelle, Machado, Isis Eloah, Madotto, Fabiana, Abd El Razek, Hassan Magdy, Abd El Razek, Muhammed Magdy, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malta, Deborah Carvalho, Mapoma, Chabila Christopher, Martinez-Raga, Jose, Maulik, Pallab K., Mazidi, Mohsen, Mckee, Martin, Mehta, Varshil, Meier, Toni, Mekonen, Tesfa, Meles, Kidanu Gebremariam, Melese, Addisu, Memiah, Peter T. N., Mendoza, Walter, Mengistu, Desalegn Tadese, Mensah, George A., Meretoja, Tuomo J., Mezgebe, Haftay Berhane, Miazgowski, Tomasz, Miller, Ted R., Mini, G. K., Mirica, Andreea, Mirrakhimov, Erkin M., Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammadifard, Noushin, Mohammed, Shafiu, Monasta, Lorenzo, Moraga, Paula, Morawska, Lidia, Jalu, Moti Tolera, Mousavi, Seyyed Meysam, Mukhopadhyay, Satinath, Musa, Kamarul Imran, Naheed, Aliya, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nansseu, Jobert Richie, Nayak, Mudavath Siva Durga Prasad, Nejjari, Chakib, Neupane, Subas, Neupane, Sudan Prasad, Ngunjiri, Josephine W., Nguyen, Cuong Tat, Nguyen, Long Hoang, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Noubiap, Jean Jacques, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T., Olivares, Pedro R., Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oommen, Anu Mary, Oren, Eyal, Orpana, Heather M., Ortega-Altamirano, Doris D., V, Ortiz, Justin R., Ota, Erika, Owolabi, Mayowa Ojo, Oyekale, Abayomi Samuel, Mahesh, P. A., Pana, Adrian, Park, Eun-Kee, Parry, Charles D. H., Parsian, Hadi, Patle, Ajay, Patton, George C., Paudel, Deepak, Petzold, Max, Phillips, Michael R., Pillay, Julian David, Postma, Maarten J., Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Rajsic, Sasa, Raju, Sree Bhushan, Ram, Usha, Rana, Saleem M., Ranabhat, Chhabi Lal, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C., Reis, Cesar, Renzaho, Andre M. N., Rezai, Mohammad Sadegh, Roever, Leonardo, Ronfani, Luca, Room, Robin, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A., Roy, Ambuj, Sabde, Yogesh Damodar, Saddik, Basema, Safiri, Saeid, Sahebkar, Amirhossein, Saleem, Zikria, Salomon, Joshua A., Salvi, Sundeep Santosh, Sanabria, Juan, Dolores Sanchez-Nino, Maria, Santomauro, Damian Francesco, Santos, Itamar S., Milicevic, Milena M. M. Santric, Sarker, Abdur Razzaque, Sarmiento-Suarez, Rodrigo, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete, Schaub, Michael P., Schmidt, Maria Ines, Schneider, Ione J. C., Schoettker, Ben, Schutte, Aletta Elisabeth, Schwendicke, Falk, Sepanlou, Sadaf G., Shaikh, Masood A. Ali, Sharif, Mehdi, She, Jun, Sheikh, Aziz, Shen, Jiabin, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shukla, Sharvari Rahul, Sigfusdottir, Inga Dora, Santos Silva, Diego Augusto, Da Silva, Natacha Torres, Alves Silveira, Dayane Gabriele, Sinha, Dhirendra Narain Narain, Sitas, Freddy, Soares Filho, Adauto Martins, Soofi, Moslem, Sorensen, Reed J. D., Soriano, Joan B., Sreeramareddy, Chandrashekhar T., Steckling, Nadine, Stein, Dan J., Sufiyan, Mu'awiyyah Babale, Sur, Patrick J., Sykes, Bryan L., Tabares-Seisdedos, Rafael, Tabuchi, Takahiro, Tavakkoli, Mohammad, Tehrani-Banihashemi, Arash, Tekle, Merhawi Gebremedhin, Thapa, Subash, Thomas, Nihal, Topor-Madry, Roman, Topouzis, Fotis, Tran, Bach Xuan, Troeger, Christopher E., Truelsen, Thomas Clement, Tsilimparis, Nikolaos, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Uthman, Olalekan A., Valdez, Pascual R., Van Boven, Job F. M., Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Violante, Francesco S., Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yuan-Pang, Weiderpass, Elisabete, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A., Widecka, Justyna, Wijeratne, Tissa, Wyper, Grant M. A., Xu, Gelin, Yamada, Tomohide, Yano, Yuichiro, Ye, Pengpeng, Yimer, Ebrahim M., Yip, Paul, Yirsaw, Biruck Desalegn, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z., Zachariah, Geevar, Zaidi, Zoubida, Zamani, Mohammad, Zhang, Xueying, Zodpey, Sanjay, Mokdad, Ali H., Naghavi, Mohsen, Murray, Christopher J. L., Gakidou, Emmanuela, Griswold, Max G., Fullman, Nancy, Hawley, Caitlin, Arian, Nicholas, Zimsen, Stephanie R. M., Tymeson, Hayley D., Venkateswaran, Vidhya, Tapp, Austin Douglas, Forouzanfar, Mohammad H., Salama, Joseph S., Abate, Kalkidan Hassen, Abate, Degu, Abay, Solomon M., Abbafati, Cristiana, Abdulkader, Rizwan Suliankatchi, Abebe, Zegeye, Aboyans, Victor, Abrar, Mohammed Mehdi, Acharya, Pawan, Adetokunboh, Olatunji O., Adhikari, Tara Ballav, Adsuar, Jose C., Afarideh, Mohsen, Agardh, Emilie Elisabet, Agarwal, Gina, Aghayan, Sargis Aghasi, Agrawal, Sutapa, Ahmed, Muktar Beshir, Akibu, Mohammed, Akinyemiju, Tomi, Akseer, Nadia, Al Asfoor, Deena H., Al-Aly, Ziyad, Alahdab, Fares, Alam, Khurshid, Albujeer, Ammar, Alene, Kefyalew Addis, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T., Aminde, Leopold N., Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T., Aremu, Olatunde, Arnlov, Johan, Artaman, Al, Aryal, Krishna K., Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F. G. A., Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B., Azzopardi, Peter S., Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H., Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Bejot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A., Bensenor, Isabela M., Bernabe, Eduardo, Bernstein, Robert S., Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A., Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjorge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, Soufiane, Bragazzi, Nicola Luigi, Brenner, Hermann, Butt, Zahid A., Cahuana-Hurtado, Lucero, Calabria, Bianca, Campos-Nonato, Ismael R., Campuzano Rincon, Julio Cesar, Carreras, Giulia, Carrero, Juan J., Carvalho, Felix, Castaneda-Orjuela, Carlos A., Castillo Rivas, Jacqueline, Catala-Lopez, Ferran, Chang, Jung-Chen, Charlson, Fiona J., Chattopadhyay, Aparajita, Chaturvedi, Pankaj, Chowdhury, Rajiv, Christopher, Devasahayam J., Chung, Sheng-Chia, Ciobanu, Liliana G., Claro, Rafael M., Conti, Sara, Cousin, Ewerton, Criqui, Michael H., Dachew, Berihun Assefa, Dargan, Paul, I, Daryani, Ahmad, Das Neves, Jose, Davletov, Kairat, De Castro, Filipa, De Courten, Barbora, De Neve, Jan-Walter, Degenhardt, Louisa, Demoz, Gebre Teklemariam, Des Jarlais, Don C., Dey, Subhojit, Dhaliwal, Rupinder Singh, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Doku, David Teye, Doyle, Kerrie E., Dubey, Manisha, Dubljanin, Eleonora, Duncan, Bruce B., Ebrahimi, Hedyeh, Edessa, Dumessa, Zaki, Maysaa El Sayed, Ermakov, Sergei Petrovich, Erskine, Holly E., Esteghamati, Alireza, Faramarzi, Mahbobeh, Farioli, Andrea, Faro, Andre, Farvid, Maryam S., Farzadfar, Farshad, Feigin, Valery L., Felisbino-Mendes, Mariana Santos, Fernandes, Eduarda, Ferrari, Alize J., Ferri, Cleusa P., Fijabi, Daniel Obadare, Filip, Irina, Finger, Jonas David, Fischer, Florian, Flaxman, Abraham D., Franklin, Richard Charles, Futran, Neal D., Gallus, Silvano, Ganji, Morsaleh, Gankpe, Fortune Gbetoho, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M., Ghadimi, Reza, Ghandour, Lilian A., Ghimire, Mamata, Gill, Paramjit Singh, Ginawi, Ibrahim Abdelmageed, Giref, Ababi Zergaw Z., Gona, Philimon N., Gopalani, Sameer Vali, Gotay, Carolyn C., Goulart, Alessandra C., Greaves, Felix, Grosso, Giuseppe, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Alma Gutierrez, Reyna, Gvs, Murthy, Hafezi-Nejad, Nima, Hagos, Tekleberhan Beyene, Hailu, Gessessew Bugssa, Hamadeh, Randah R., Hamidi, Samer, Hankey, Graeme J., Harb, Hilda L., Harikrishnan, Sivadasanpillai, Maria Haro, Josep, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hay, Simon, I, Heibati, Behzad, Henok, Andualem, Heredia-Pi, Ileana, Francisco Hernandez-Llanes, Norberto, Herteliu, Claudiu, Hibstu, Desalegn Ts Tsegaw, Hoogar, Praveen, Horita, Nobuyuki, Hosgood, H. Dean, Hosseini, Mostafa, Hostiuc, Mihaela, Hu, Guoqing, Huang, Hsiang, Husseini, Abdullatif, Idrisov, Bulat, Ileanu, Bogdan Vasile, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Jackson, Maria D., Jakovljevic, Mihajlo, Jayatilleke, Achala Upendra, Jha, Ravi Prakash, Jonas, Jost B., Jozwiak, Jacek Jerzy, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kapil, Umesh, Kasaeian, Amir, Kassa, Tesfaye D. Dessale, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Kebede, Seifu, Kefale, Adane Teshome, Keiyoro, Peter Njenga, Kengne, Andre Pascal, Khader, Yousef, Khafaie, Morteza Abdullatif, Khalil, Ibrahim A., Khan, Md Nuruzzaman, Khang, Young-Ho, Khater, Mona M., Khubchandani, Jagdish, Kim, Cho-Il, Kim, Daniel, Kim, Yun Jin, Kimokoti, Ruth W., Kisa, Adnan, Kivimaki, Mika, Kochhar, Sonali, Kosen, Soewarta, Koul, Parvaiz A., Koyanagi, Ai, Krishan, Kewal, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kulkarni, Veena S., Kumar, Pushpendra, Lafranconi, Alessandra, Balaji, Arjun Lakshmana, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lami, Faris Hasan, Lan, Qing, Lang, Justin J., Lansky, Sonia, Larsson, Anders O., Latifi, Arman, Leasher, Janet L., Lee, Paul H., Leigh, James, Leinsalu, Mall, Leung, Janni, Levi, Miriam, Li, Yichong, Lim, Lee-Ling, Linn, Shai, Liu, Shiwei, Lobato-Cordero, Andrea, Lotufo, Paulo A., King Macarayan, Erlyn Rachelle, Machado, Isis Eloah, Madotto, Fabiana, Abd El Razek, Hassan Magdy, Abd El Razek, Muhammed Magdy, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malta, Deborah Carvalho, Mapoma, Chabila Christopher, Martinez-Raga, Jose, Maulik, Pallab K., Mazidi, Mohsen, Mckee, Martin, Mehta, Varshil, Meier, Toni, Mekonen, Tesfa, Meles, Kidanu Gebremariam, Melese, Addisu, Memiah, Peter T. N., Mendoza, Walter, Mengistu, Desalegn Tadese, Mensah, George A., Meretoja, Tuomo J., Mezgebe, Haftay Berhane, Miazgowski, Tomasz, Miller, Ted R., Mini, G. K., Mirica, Andreea, Mirrakhimov, Erkin M., Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammadifard, Noushin, Mohammed, Shafiu, Monasta, Lorenzo, Moraga, Paula, Morawska, Lidia, Jalu, Moti Tolera, Mousavi, Seyyed Meysam, Mukhopadhyay, Satinath, Musa, Kamarul Imran, Naheed, Aliya, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nansseu, Jobert Richie, Nayak, Mudavath Siva Durga Prasad, Nejjari, Chakib, Neupane, Subas, Neupane, Sudan Prasad, Ngunjiri, Josephine W., Nguyen, Cuong Tat, Nguyen, Long Hoang, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Noubiap, Jean Jacques, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T., Olivares, Pedro R., Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oommen, Anu Mary, Oren, Eyal, Orpana, Heather M., Ortega-Altamirano, Doris D., V, Ortiz, Justin R., Ota, Erika, Owolabi, Mayowa Ojo, Oyekale, Abayomi Samuel, Mahesh, P. A., Pana, Adrian, Park, Eun-Kee, Parry, Charles D. H., Parsian, Hadi, Patle, Ajay, Patton, George C., Paudel, Deepak, Petzold, Max, Phillips, Michael R., Pillay, Julian David, Postma, Maarten J., Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Rajsic, Sasa, Raju, Sree Bhushan, Ram, Usha, Rana, Saleem M., Ranabhat, Chhabi Lal, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C., Reis, Cesar, Renzaho, Andre M. N., Rezai, Mohammad Sadegh, Roever, Leonardo, Ronfani, Luca, Room, Robin, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A., Roy, Ambuj, Sabde, Yogesh Damodar, Saddik, Basema, Safiri, Saeid, Sahebkar, Amirhossein, Saleem, Zikria, Salomon, Joshua A., Salvi, Sundeep Santosh, Sanabria, Juan, Dolores Sanchez-Nino, Maria, Santomauro, Damian Francesco, Santos, Itamar S., Milicevic, Milena M. M. Santric, Sarker, Abdur Razzaque, Sarmiento-Suarez, Rodrigo, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete, Schaub, Michael P., Schmidt, Maria Ines, Schneider, Ione J. C., Schoettker, Ben, Schutte, Aletta Elisabeth, Schwendicke, Falk, Sepanlou, Sadaf G., Shaikh, Masood A. Ali, Sharif, Mehdi, She, Jun, Sheikh, Aziz, Shen, Jiabin, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shukla, Sharvari Rahul, Sigfusdottir, Inga Dora, Santos Silva, Diego Augusto, Da Silva, Natacha Torres, Alves Silveira, Dayane Gabriele, Sinha, Dhirendra Narain Narain, Sitas, Freddy, Soares Filho, Adauto Martins, Soofi, Moslem, Sorensen, Reed J. D., Soriano, Joan B., Sreeramareddy, Chandrashekhar T., Steckling, Nadine, Stein, Dan J., Sufiyan, Mu'awiyyah Babale, Sur, Patrick J., Sykes, Bryan L., Tabares-Seisdedos, Rafael, Tabuchi, Takahiro, Tavakkoli, Mohammad, Tehrani-Banihashemi, Arash, Tekle, Merhawi Gebremedhin, Thapa, Subash, Thomas, Nihal, Topor-Madry, Roman, Topouzis, Fotis, Tran, Bach Xuan, Troeger, Christopher E., Truelsen, Thomas Clement, Tsilimparis, Nikolaos, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Uthman, Olalekan A., Valdez, Pascual R., Van Boven, Job F. M., Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Violante, Francesco S., Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yuan-Pang, Weiderpass, Elisabete, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A., Widecka, Justyna, Wijeratne, Tissa, Wyper, Grant M. A., Xu, Gelin, Yamada, Tomohide, Yano, Yuichiro, Ye, Pengpeng, Yimer, Ebrahim M., Yip, Paul, Yirsaw, Biruck Desalegn, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z., Zachariah, Geevar, Zaidi, Zoubida, Zamani, Mohammad, Zhang, Xueying, Zodpey, Sanjay, Mokdad, Ali H., Naghavi, Mohsen, Murray, Christopher J. L., and Gakidou, Emmanuela
- Abstract
Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods: Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings: Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2.2% (95% uncertainty interval [UI] 1.5-3.0) of age-standardised female deaths and 6.8% (5.8-8.0) of age-standardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3.8% (95% UI 3.2-4-3) of female deaths and 12.2% (10.8-13-6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2.3% (95% UI 2.0-2.6) and male attribut, Funding: Bill & Melinda Gates Foundation
- Published
- 2018
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21. Alcohol use and burden for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016
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Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F, Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H, Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Béjot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A, Bensenor, Isabela M, Bernabe, Eduardo, Bernstein, Robert S, Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, 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Desalegn, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Zachariah, Geevar, Zaidi, Zoubida, Zamani, Mohammad, Zhang, Xueying, Zodpey, Sanjay, Mokdad, Ali H, Naghavi, Mohsen, Murray, Christopher J L, and Gakidou, Emmanuela
- Abstract
Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted lifeyears (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods: Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings: Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5-3·0) of age-standardised female deaths and 6·8% (5·8-8·0) of agestandardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2-4·3) of female deaths and 12·2% (10·8-13·6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2·3% (95% UI 2·0-2·6) and male attributab
- Published
- 2018
22. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
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Troeger, C, Blacker, B, Khalil, I, Rao, P, Cao, J, Zimsen, S, Albertson, S, Deshpande, A, Farag, T, Abebe, Z, Adetifa, I, Adhikari, T, Akibu, M, Al Lami, F, Al-Eyadhy, A, Alvis-Guzman, N, Amare, A, Amoako, Y, Antonio, C, Aremu, O, Asfaw, E, Asgedom, S, Atey, T, Attia, E, Avokpaho, E, Ayele, H, Ayuk, T, Balakrishnan, K, Barac, A, Bassat, Q, Behzadifar, M, Bhaumik, S, Bhutta, Z, Bijani, A, Brauer, M, Brown, A, Camargos, P, Castañeda-Orjuela, C, Colombara, D, Conti, S, Dadi, A, Dandona, L, Dandona, R, Do, H, Dubljanin, E, Edessa, D, Elkout, H, Endries, A, Fijabi, D, Foreman, K, Forouzanfar, M, Fullman, N, Garcia-Basteiro, A, Gessner, B, Gething, P, Gupta, R, Gupta, T, Hailu, G, Hassen, H, Hedayati, M, Heidari, M, Hibstu, D, Horita, N, Ilesanmi, O, Jakovljevic, M, Jamal, A, Kahsay, A, Kasaeian, A, Kassa, D, Khader, Y, Khan, E, Khan, M, Khang, Y, Kim, Y, Kissoon, N, Knibbs, L, Kochhar, S, Koul, P, Kumar, G, Lodha, R, Magdy Abd El Razek, H, Malta, D, Mathew, J, Mengistu, D, Mezgebe, H, Mohammad, K, Mohammed, M, Momeniha, F, Murthy, S, Nguyen, C, Nielsen, K, Ningrum, D, Nirayo, Y, Oren, E, Ortiz, J, Pa, M, Postma, M, Qorbani, M, Quansah, R, Rai, R, Rana, S, Ranabhat, C, Ray, S, Rezai, M, Ruhago, G, Safiri, S, Salomon, J, Sartorius, B, Savic, M, Sawhney, M, She, J, Sheikh, A, Shiferaw, M, Shigematsu, M, Singh, J, Somayaji, R, Stanaway, J, Sufiyan, M, Taffere, G, Temsah, M, Thompson, M, Tobe-Gai, R, Topor-Madry, R, Tran, B, Tran, T, Tuem, K, Ukwaja, K, Vollset, S, Walson, J, Weldegebreal, F, Werdecker, A, West, T, Yonemoto, N, Zaki, M, Zhou, L, Zodpey, S, Vos, T, Naghavi, M, Lim, S, Mokdad, A, Murray, C, Hay, S, Reiner, R, Troeger, Christopher, Blacker, Brigette, Khalil, Ibrahim A, Rao, Puja C, Cao, Jackie, Zimsen, Stephanie R M, Albertson, Samuel B, Deshpande, Aniruddha, Farag, Tamer, Abebe, Zegeye, Adetifa, Ifedayo Morayo O, Adhikari, Tara Ballav, Akibu, Mohammed, Al Lami, Faris Hasan, Al-Eyadhy, Ayman, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amoako, Yaw Ampem, Antonio, Carl Abelardo T, Aremu, Olatunde, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Atey, Tesfay Mehari, Attia, Engi Farouk, Avokpaho, Euripide Frinel G Arthur, Ayele, Henok Tadesse, Ayuk, Tambe Betrand, Balakrishnan, Kalpana, Barac, Aleksandra, Bassat, Quique, Behzadifar, Masoud, Behzadifar, Meysam, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Bijani, Ali, Brauer, Michael, Brown, Alexandria, Camargos, Paulo A M, Castañeda-Orjuela, Carlos A, Colombara, Danny, Conti, Sara, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Do, Huyen Phuc, Dubljanin, Eleonora, Edessa, Dumessa, Elkout, Hajer, Endries, Aman Yesuf, Fijabi, Daniel Obadare, Foreman, Kyle J, Forouzanfar, Mohammad H, Fullman, Nancy, Garcia-Basteiro, Alberto L, Gessner, Bradford D, Gething, Peter W, Gupta, Rahul, Gupta, Tarun, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hedayati, Mohammad T, Heidari, Mohsen, Hibstu, Desalegn Tsegaw, Horita, Nobuyuki, Ilesanmi, Olayinka S, Jakovljevic, Mihajlo B, Jamal, Amr A, Kahsay, Amaha, Kasaeian, Amir, Kassa, Dessalegn Haile, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Md Nuruzzaman, Khang, Young-Ho, Kim, Yun Jin, Kissoon, Niranjan, Knibbs, Luke D, Kochhar, Sonali, Koul, Parvaiz A, Kumar, G Anil, Lodha, Rakesh, Magdy Abd El Razek, Hassan, Malta, Deborah Carvalho, Mathew, Joseph L, Mengistu, Desalegn Tadese, Mezgebe, Haftay Berhane, Mohammad, Karzan Abdulmuhsin, Mohammed, Mohammed A, Momeniha, Fatemeh, Murthy, Srinivas, Nguyen, Cuong Tat, Nielsen, Katie R, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Oren, Eyal, Ortiz, Justin R, PA, Mahesh, Postma, Maarten J, Qorbani, Mostafa, Quansah, Reginald, Rai, Rajesh Kumar, Rana, Saleem M, Ranabhat, Chhabi Lal, Ray, Sarah E, Rezai, Mohammad Sadegh, Ruhago, George Mugambage, Safiri, Saeid, Salomon, Joshua A, Sartorius, Benn, Savic, Miloje, Sawhney, Monika, She, Jun, Sheikh, Aziz, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Singh, Jasvinder A, Somayaji, Ranjani, Stanaway, Jeffrey D, Sufiyan, Muawiyyah Babale, Taffere, Getachew Redae, Temsah, Mohamad-Hani, Thompson, Matthew J, Tobe-Gai, Ruoyan, Topor-Madry, Roman, Tran, Bach Xuan, Tran, Tung Thanh, Tuem, Kald Beshir, Ukwaja, Kingsley Nnanna, Vollset, Stein Emil, Walson, Judd L, Weldegebreal, Fitsum, Werdecker, Andrea, West, T Eoin, Yonemoto, Naohiro, Zaki, Maysaa El Sayed, Zhou, Lei, Zodpey, Sanjay, Vos, Theo, Naghavi, Mohsen, Lim, Stephen S, Mokdad, Ali H, Murray, Christopher J L, Hay, Simon I, Reiner, Robert C, Troeger, C, Blacker, B, Khalil, I, Rao, P, Cao, J, Zimsen, S, Albertson, S, Deshpande, A, Farag, T, Abebe, Z, Adetifa, I, Adhikari, T, Akibu, M, Al Lami, F, Al-Eyadhy, A, Alvis-Guzman, N, Amare, A, Amoako, Y, Antonio, C, Aremu, O, Asfaw, E, Asgedom, S, Atey, T, Attia, E, Avokpaho, E, Ayele, H, Ayuk, T, Balakrishnan, K, Barac, A, Bassat, Q, Behzadifar, M, Bhaumik, S, Bhutta, Z, Bijani, A, Brauer, M, Brown, A, Camargos, P, Castañeda-Orjuela, C, Colombara, D, Conti, S, Dadi, A, Dandona, L, Dandona, R, Do, H, Dubljanin, E, Edessa, D, Elkout, H, Endries, A, Fijabi, D, Foreman, K, Forouzanfar, M, Fullman, N, Garcia-Basteiro, A, Gessner, B, Gething, P, Gupta, R, Gupta, T, Hailu, G, Hassen, H, Hedayati, M, Heidari, M, Hibstu, D, Horita, N, Ilesanmi, O, Jakovljevic, M, Jamal, A, Kahsay, A, Kasaeian, A, Kassa, D, Khader, Y, Khan, E, Khan, M, Khang, Y, Kim, Y, Kissoon, N, Knibbs, L, Kochhar, S, Koul, P, Kumar, G, Lodha, R, Magdy Abd El Razek, H, Malta, D, Mathew, J, Mengistu, D, Mezgebe, H, Mohammad, K, Mohammed, M, Momeniha, F, Murthy, S, Nguyen, C, Nielsen, K, Ningrum, D, Nirayo, Y, Oren, E, Ortiz, J, Pa, M, Postma, M, Qorbani, M, Quansah, R, Rai, R, Rana, S, Ranabhat, C, Ray, S, Rezai, M, Ruhago, G, Safiri, S, Salomon, J, Sartorius, B, Savic, M, Sawhney, M, She, J, Sheikh, A, Shiferaw, M, Shigematsu, M, Singh, J, Somayaji, R, Stanaway, J, Sufiyan, M, Taffere, G, Temsah, M, Thompson, M, Tobe-Gai, R, Topor-Madry, R, Tran, B, Tran, T, Tuem, K, Ukwaja, K, Vollset, S, Walson, J, Weldegebreal, F, Werdecker, A, West, T, Yonemoto, N, Zaki, M, Zhou, L, Zodpey, S, Vos, T, Naghavi, M, Lim, S, Mokdad, A, Murray, C, Hay, S, Reiner, R, Troeger, Christopher, Blacker, Brigette, Khalil, Ibrahim A, Rao, Puja C, Cao, Jackie, Zimsen, Stephanie R M, Albertson, Samuel B, Deshpande, Aniruddha, Farag, Tamer, Abebe, Zegeye, Adetifa, Ifedayo Morayo O, Adhikari, Tara Ballav, Akibu, Mohammed, Al Lami, Faris Hasan, Al-Eyadhy, Ayman, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amoako, Yaw Ampem, Antonio, Carl Abelardo T, Aremu, Olatunde, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Atey, Tesfay Mehari, Attia, Engi Farouk, Avokpaho, Euripide Frinel G Arthur, Ayele, Henok Tadesse, Ayuk, Tambe Betrand, Balakrishnan, Kalpana, Barac, Aleksandra, Bassat, Quique, Behzadifar, Masoud, Behzadifar, Meysam, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Bijani, Ali, Brauer, Michael, Brown, Alexandria, Camargos, Paulo A M, Castañeda-Orjuela, Carlos A, Colombara, Danny, Conti, Sara, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Do, Huyen Phuc, Dubljanin, Eleonora, Edessa, Dumessa, Elkout, Hajer, Endries, Aman Yesuf, Fijabi, Daniel Obadare, Foreman, Kyle J, Forouzanfar, Mohammad H, Fullman, Nancy, Garcia-Basteiro, Alberto L, Gessner, Bradford D, Gething, Peter W, Gupta, Rahul, Gupta, Tarun, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hedayati, Mohammad T, Heidari, Mohsen, Hibstu, Desalegn Tsegaw, Horita, Nobuyuki, Ilesanmi, Olayinka S, Jakovljevic, Mihajlo B, Jamal, Amr A, Kahsay, Amaha, Kasaeian, Amir, Kassa, Dessalegn Haile, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Md Nuruzzaman, Khang, Young-Ho, Kim, Yun Jin, Kissoon, Niranjan, Knibbs, Luke D, Kochhar, Sonali, Koul, Parvaiz A, Kumar, G Anil, Lodha, Rakesh, Magdy Abd El Razek, Hassan, Malta, Deborah Carvalho, Mathew, Joseph L, Mengistu, Desalegn Tadese, Mezgebe, Haftay Berhane, Mohammad, Karzan Abdulmuhsin, Mohammed, Mohammed A, Momeniha, Fatemeh, Murthy, Srinivas, Nguyen, Cuong Tat, Nielsen, Katie R, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Oren, Eyal, Ortiz, Justin R, PA, Mahesh, Postma, Maarten J, Qorbani, Mostafa, Quansah, Reginald, Rai, Rajesh Kumar, Rana, Saleem M, Ranabhat, Chhabi Lal, Ray, Sarah E, Rezai, Mohammad Sadegh, Ruhago, George Mugambage, Safiri, Saeid, Salomon, Joshua A, Sartorius, Benn, Savic, Miloje, Sawhney, Monika, She, Jun, Sheikh, Aziz, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Singh, Jasvinder A, Somayaji, Ranjani, Stanaway, Jeffrey D, Sufiyan, Muawiyyah Babale, Taffere, Getachew Redae, Temsah, Mohamad-Hani, Thompson, Matthew J, Tobe-Gai, Ruoyan, Topor-Madry, Roman, Tran, Bach Xuan, Tran, Tung Thanh, Tuem, Kald Beshir, Ukwaja, Kingsley Nnanna, Vollset, Stein Emil, Walson, Judd L, Weldegebreal, Fitsum, Werdecker, Andrea, West, T Eoin, Yonemoto, Naohiro, Zaki, Maysaa El Sayed, Zhou, Lei, Zodpey, Sanjay, Vos, Theo, Naghavi, Mohsen, Lim, Stephen S, Mokdad, Ali H, Murray, Christopher J L, Hay, Simon I, and Reiner, Robert C
- Abstract
Background: Lower respiratory infections are a leading cause of morbidity and mortality around the world. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, provides an up-to-date analysis of the burden of lower respiratory infections in 195 countries. This study assesses cases, deaths, and aetiologies spanning the past 26 years and shows how the burden of lower respiratory infection has changed in people of all ages. Methods: We used three separate modelling strategies for lower respiratory infections in GBD 2016: a Bayesian hierarchical ensemble modelling platform (Cause of Death Ensemble model), which uses vital registration, verbal autopsy data, and surveillance system data to predict mortality due to lower respiratory infections; a compartmental meta-regression tool (DisMod-MR), which uses scientific literature, population representative surveys, and health-care data to predict incidence, prevalence, and mortality; and modelling of counterfactual estimates of the population attributable fraction of lower respiratory infection episodes due to Streptococcus pneumoniae, Haemophilus influenzae type b, influenza, and respiratory syncytial virus. We calculated each modelled estimate for each age, sex, year, and location. We modelled the exposure level in a population for a given risk factor using DisMod-MR and a spatio-temporal Gaussian process regression, and assessed the effectiveness of targeted interventions for each risk factor in children younger than 5 years. We also did a decomposition analysis of the change in LRI deaths from 2000–16 using the risk factors associated with LRI in GBD 2016. Findings: In 2016, lower respiratory infections caused 652 572 deaths (95% uncertainty interval [UI] 586 475–720 612) in children younger than 5 years (under-5s), 1 080 958 deaths (943 749–1 170 638) in adults older than 70 years, and 2 377 697 deaths (2 145 584–2 512 809) in people of all ages, worldwide. Streptococcus pneumoniae was the leading ca
- Published
- 2018
23. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016
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Fullman, N, Yearwood, J, Abay, S, Abbafati, C, Abd-Allah, F, Abdela, J, Abdelalim, A, Abebe, Z, Abebo, T, Aboyans, V, Abraha, H, Abreu, D, Abu-Raddad, L, Adane, A, Adedoyin, R, Adetokunboh, O, Adhikari, T, Afarideh, M, Afshin, A, Agarwal, G, Agius, D, Agrawal, A, Agrawal, S, Ahmad Kiadaliri, A, Aichour, M, Akibu, M, Akinyemi, R, Akinyemiju, T, Akseer, N, Al Lami, F, Alahdab, F, Al-Aly, Z, Alam, K, Alam, T, Alasfoor, D, Albittar, M, Alene, K, Al-Eyadhy, A, Ali, S, Alijanzadeh, M, Aljunid, S, Alkerwi, A, Alla, F, Allebeck, P, Allen, C, Alomari, M, Al-Raddadi, R, Alsharif, U, Altirkawi, K, Alvis-Guzman, N, Amare, A, Amenu, K, Ammar, W, Amoako, Y, Anber, N, Andrei, C, Androudi, S, Antonio, C, Araújo, V, Aremu, O, Ärnlöv, J, Artaman, A, Aryal, K, Asayesh, H, Asfaw, E, Asgedom, S, Asghar, R, Ashebir, M, Asseffa, N, Atey, T, Atre, S, Atteraya, M, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Ayala Quintanilla, B, Ayalew, A, Ayele, H, Ayer, R, Ayuk, T, Azzopardi, P, Azzopardi-Muscat, N, Babalola, T, Badali, H, Badawi, A, Banach, M, Banerjee, A, Banstola, A, Barber, R, Barboza, M, Barker-Collo, S, Bärnighausen, T, Barquera, S, Barrero, L, Bassat, Q, Basu, S, Baune, B, Bazargan-Hejazi, S, Bedi, N, Beghi, E, Behzadifar, M, Bekele, B, Belachew, A, Belay, S, Belay, Y, Bell, M, Bello, A, Bennett, D, Bennett, J, Bensenor, I, Berhe, D, Bernabé, E, Bernstein, R, Beuran, M, Bhalla, A, Bhatt, P, Bhaumik, S, Bhutta, Z, Biadgo, B, Bijani, A, Bikbov, B, Birungi, C, Biryukov, S, Bizuneh, H, Bolliger, I, Bolt, K, Bou-Orm, I, Bozorgmehr, K, Brady, O, Brazinova, A, Breitborde, N, Brenner, H, Britton, G, Brugha, T, Butt, Z, Cahuana-Hurtado, L, Campos-Nonato, I, Campuzano, J, Car, J, Car, M, Cárdenas, R, Carrero, J, Carvalho, F, Castañeda-Orjuela, C, Castillo Rivas, J, Catalá-López, F, Cercy, K, Chalek, J, Chang, H, Chang, J, Chattopadhyay, A, Chaturvedi, P, Chiang, P, Chisumpa, V, Choi, J, Christensen, H, Christopher, D, Chung, S, Ciobanu, L, Cirillo, M, Colombara, D, Conti, S, Cooper, C, Cornaby, L, Cortesi, P, Cortinovis, M, Costa Pereira, A, Cousin, E, Criqui, M, Cromwell, E, Crowe, C, Crump, J, Daba, A, Dachew, B, Dadi, A, Dandona, L, Dandona, R, Dargan, P, Daryani, A, Daryani, M, Das, J, Das, S, das Neves, J, Davis Weaver, N, Davletov, K, de Courten, B, De Leo, D, De Neve, J, Dellavalle, R, Demoz, G, Deribe, K, Des Jarlais, D, Dey, S, Dharmaratne, S, Dhimal, M, Djalalinia, S, Doku, D, Dolan, K, Dorsey, E, dos Santos, K, Doyle, K, Driscoll, T, Dubey, M, Dubljanin, E, Duncan, B, Echko, M, Edessa, D, Edvardsson, D, Ehrlich, J, Eldrenkamp, E, El-Khatib, Z, Endres, M, Endries, A, Eshrati, B, Eskandarieh, S, Esteghamati, A, Fakhar, M, Farag, T, Faramarzi, M, Faraon, E, Faro, A, Farzadfar, F, Fatusi, A, Fazeli, M, Feigin, V, Feigl, A, Fentahun, N, Fereshtehnejad, S, Fernandes, E, Fernandes, J, Fijabi, D, Filip, I, Fischer, F, Fitzmaurice, C, Flaxman, A, Flor, L, Foigt, N, Foreman, K, Frostad, J, Fürst, T, Futran, N, Gakidou, E, Gallus, S, Gambashidze, K, Gamkrelidze, A, Ganji, M, Gebre, A, Gebrehiwot, T, Gebremedhin, A, Gelaw, Y, Geleijnse, J, Geremew, D, Gething, P, Ghadimi, R, Ghasemi Falavarjani, K, Ghasemi-Kasman, M, Gill, P, Giref, A, Giroud, M, Gishu, M, Giussani, G, Godwin, W, Goli, S, Gomez-Dantes, H, Gona, P, Goodridge, A, Gopalani, S, Goryakin, Y, Goulart, A, Grada, A, Griswold, M, Grosso, G, Gugnani, H, Guo, Y, Gupta, R, Gupta, T, Gupta, V, Haagsma, J, Hachinski, V, Hafezi-Nejad, N, Hailu, G, Hamadeh, R, Hamidi, S, Hankey, G, Harb, H, Harewood, H, Harikrishnan, S, Haro, J, Hassen, H, Havmoeller, R, Hawley, C, Hay, S, He, J, Hearps, S, Hegazy, M, Heibati, B, Heidari, M, Hendrie, D, Henry, N, Herrera Ballesteros, V, Herteliu, C, Hibstu, D, Hiluf, M, Hoek, H, Homaie Rad, E, Horita, N, Hosgood, H, Hosseini, M, Hosseini, S, Hostiuc, M, Hostiuc, S, Hoy, D, Hsairi, M, Htet, A, Hu, G, Huang, J, Iburg, K, Idris, F, Igumbor, E, Ikeda, C, Ileanu, B, Ilesanmi, O, Innos, K, Irvani, S, Irvine, C, Islami, F, Jacobs, T, Jacobsen, K, Jahanmehr, N, Jain, R, Jain, S, Jakovljevic, M, Jalu, M, Jamal, A, Javanbakht, M, Jayatilleke, A, Jeemon, P, Jha, R, Jha, V, Jóúwiak, J, John, O, Johnson, S, Jonas, J, Joshua, V, Jürisson, M, Kabir, Z, Kadel, R, Kahsay, A, Kalani, R, Kar, C, Karanikolos, M, Karch, A, Karema, C, Karimi, S, Kasaeian, A, Kassa, D, Kassa, G, Kassa, T, Kassebaum, N, Katikireddi, S, Kaul, A, Kawakami, N, Kazanjan, K, Kebede, S, Keiyoro, P, Kemp, G, Kengne, A, Kereselidze, M, Ketema, E, Khader, Y, Khafaie, M, Khajavi, A, Khalil, I, Khan, E, Khan, G, Khan, M, Khanal, M, Khang, Y, Khater, M, Khoja, A, Khosravi, A, Khubchandani, J, Kibret, G, Kiirithio, D, Kim, D, Kim, Y, Kimokoti, R, Kinfu, Y, Kinra, S, Kisa, A, Kissoon, N, Kochhar, S, Kokubo, Y, Kopec, J, Kosen, S, Koul, P, Koyanagi, A, Kravchenko, M, Krishan, K, Krohn, K, Kuate Defo, B, Kumar, G, Kumar, P, Kutz, M, Kuzin, I, Kyu, H, Lad, D, Lafranconi, A, Lal, D, Lalloo, R, Lam, H, Lan, Q, Lang, J, Lansingh, V, Lansky, S, Larsson, A, Latifi, A, Lazarus, J, Leasher, J, Lee, P, 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Britton, Gabrielle, Brugha, Traolach S, Butt, Zahid A, Cahuana-Hurtado, Lucero, Campos-Nonato, Ismael Ricardo, Campuzano, Julio Cesar, Car, Josip, Car, Mate, Cárdenas, Rosario, Carrero, Juan Jesus, Carvalho, Felix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Catalá-López, Ferrán, Cercy, Kelly, Chalek, Julian, Chang, Hsing-Yi, Chang, Jung-Chen, Chattopadhyay, Aparajita, Chaturvedi, Pankaj, Chiang, Peggy Pei-Chia, Chisumpa, Vesper Hichilombwe, Choi, Jee-Young J, Christensen, Hanne, Christopher, Devasahayam Jesudas, Chung, Sheng-Chia, Ciobanu, Liliana G, Cirillo, Massimo, Colombara, Danny, Conti, Sara, Cooper, Cyrus, Cornaby, Leslie, Cortesi, Paolo Angelo, Cortinovis, Monica, Costa Pereira, Alexandre, Cousin, Ewerton, Criqui, Michael H, Cromwell, Elizabeth A, Crowe, Christopher Stephen, Crump, John A, Daba, Alemneh Kabeta, Dachew, Berihun Assefa, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I, Daryani, Ahmad, Daryani, Maryam, Das, Jai, Das, Siddharth Kumar, das Neves, José, Davis Weaver, Nicole, Davletov, Kairat, de Courten, Barbora, De Leo, Diego, De Neve, Jan-Walter, Dellavalle, Robert P, Demoz, Gebre, Deribe, Kebede, Des Jarlais, Don C, Dey, Subhojit, Dharmaratne, Samath D, Dhimal, Meghnath, Djalalinia, Shirin, Doku, David Teye, Dolan, Kate, Dorsey, E Ray, dos Santos, Kadine Priscila Bender, Doyle, Kerrie E, Driscoll, Tim R, Dubey, Manisha, Dubljanin, Eleonora, Duncan, Bruce Bartholow, Echko, Michelle, Edessa, Dumessa, Edvardsson, David, Ehrlich, Joshua R, Eldrenkamp, Erika, El-Khatib, Ziad Ziad, Endres, Matthias, Endries, Aman Yesuf, Eshrati, Babak, Eskandarieh, Sharareh, Esteghamati, Alireza, Fakhar, Mahdi, Farag, Tamer, Faramarzi, Mahbobeh, Faraon, Emerito Jose Aquino, Faro, André, Farzadfar, Farshad, Fatusi, Adesegun, Fazeli, Mir Sohail, Feigin, Valery L, Feigl, Andrea B, Fentahun, Netsanet, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Fernandes, João C, Fijabi, Daniel Obadare, Filip, Irina, Fischer, Florian, Fitzmaurice, Christina, Flaxman, Abraham D, Flor, Luisa Sorio, Foigt, Nataliya, Foreman, Kyle J, Frostad, Joseph J, Fürst, Thomas, Futran, Neal D, Gakidou, Emmanuela, Gallus, Silvano, Gambashidze, Ketevan, Gamkrelidze, Amiran, Ganji, Morsaleh, Gebre, Abadi Kahsu, Gebrehiwot, Tsegaye Tewelde, Gebremedhin, Amanuel Tesfay, Gelaw, Yalemzewod Assefa, Geleijnse, Johanna M, Geremew, Demeke, Gething, Peter W, Ghadimi, Reza, Ghasemi Falavarjani, Khalil, Ghasemi-Kasman, Maryam, Gill, Paramjit Singh, Giref, Ababi Zergaw, Giroud, Maurice, Gishu, Melkamu Dedefo, Giussani, Giorgia, Godwin, William W, Goli, Srinivas, Gomez-Dantes, Hector, Gona, Philimon N, Goodridge, Amador, Gopalani, Sameer Vali, Goryakin, Yevgeniy, Goulart, Alessandra Carvalho, Grada, Ayman, Griswold, Max, Grosso, Giuseppe, Gugnani, Harish Chander, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Gupta, Tanush, Gupta, Tarun, Gupta, Vipin, Haagsma, Juanita A, Hachinski, Vladimir, Hafezi-Nejad, Nima, Hailu, Gessessew Bugssa, Hamadeh, Randah Ribhi, Hamidi, Samer, Hankey, Graeme J, Harb, Hilda L, Harewood, Heather C, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hawley, Caitlin, Hay, Simon I, He, Jiawei, Hearps, Stephen J C, Hegazy, Mohamed I, Heibati, Behzad, Heidari, Mohsen, Hendrie, Delia, Henry, Nathaniel J, Herrera Ballesteros, Victor Hugo, Herteliu, Claudiu, Hibstu, Desalegn Tsegaw, Hiluf, Molla Kahssay, Hoek, Hans W, Homaie Rad, Enayatollah, Horita, Nobuyuki, Hosgood, H Dean, Hosseini, Mostafa, Hosseini, Seyed Reza, Hostiuc, Mihaela, Hostiuc, Sorin, Hoy, Damian G, Hsairi, Mohamed, Htet, Aung Soe, Hu, Guoqing, Huang, John J, Iburg, Kim Moesgaard, Idris, Fachmi, Igumbor, Ehimario Uche, Ikeda, Chad, Ileanu, Bogdan Vasile, Ilesanmi, Olayinka S, Innos, Kaire, Irvani, Seyed Sina Naghibi, Irvine, Caleb M S, Islami, Farhad, Jacobs, Troy A, Jacobsen, Kathryn H, Jahanmehr, Nader, Jain, Rajesh, Jain, Sudhir Kumar, Jakovljevic, Mihajlo B, Jalu, Moti Tolera, Jamal, Amr A, Javanbakht, Mehdi, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jha, Ravi Prakash, Jha, Vivekanand, Jóúwiak, Jacek, John, Oommen, Johnson, Sarah Charlotte, Jonas, Jost B, Joshua, Vasna, Jürisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kalani, Rizwan, Kar, Chittaranjan, Karanikolos, Marina, Karch, André, Karema, Corine Kakizi, Karimi, Seyed M, Kasaeian, Amir, Kassa, Dessalegn Haile, Kassa, Getachew Mullu, Kassa, Tesfaye Dessale, Kassebaum, Nicholas J, Katikireddi, Srinivasa Vittal, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Kebede, Seifu, Keiyoro, Peter Njenga, Kemp, Grant Rodgers, Kengne, Andre Pascal, Kereselidze, Maia, Ketema, Ezra Belay, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khajavi, Alireza, Khalil, Ibrahim A, Khan, Ejaz Ahmad, Khan, Gulfaraz, Khan, Md Nuruzzaman, Khan, Muhammad Ali, Khanal, Mukti Nath, Khang, Young-Ho, Khater, Mona M, Khoja, Abdullah Tawfih Abdullah, Khosravi, Ardeshir, Khubchandani, Jagdish, Kibret, Getiye Dejenu, Kiirithio, Daniel Ngari, Kim, Daniel, Kim, Yun Jin, Kimokoti, Ruth W, Kinfu, Yohannes, Kinra, Sanjay, Kisa, Adnan, Kissoon, Niranjan, Kochhar, Sonali, Kokubo, Yoshihiro, Kopec, Jacek A, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Kravchenko, Michael, Krishan, Kewal, Krohn, Kristopher J, Kuate Defo, Barthelemy, Kumar, G Anil, Kumar, Pushpendra, Kutz, Michael, Kuzin, Igor, Kyu, Hmwe H, Lad, Deepesh Pravinkumar, Lafranconi, Alessandra, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lam, Hilton, Lan, Qing, Lang, Justin J, Lansingh, Van C, Lansky, Sonia, Larsson, Anders, Latifi, Arman, Lazarus, Jeffrey Victor, Leasher, Janet L, Lee, Paul H, Legesse, Yirga, Leigh, James, Leshargie, Cheru Tesema, Leta, Samson, Leung, Janni, Leung, Ricky, Levi, Miriam, Li, Yongmei, Liang, Juan, Liben, Misgan Legesse, Lim, Lee-Ling, Lim, Stephen S, Lind, Margaret, Linn, Shai, Listl, Stefan, Liu, Patrick, Liu, Shiwei, Lodha, Rakesh, Lopez, Alan D, Lorch, Scott A, Lorkowski, Stefan, Lotufo, Paulo A, Lucas, Timothy C D, Lunevicius, Raimundas, Lurton, Grégoire, Lyons, Ronan A, Maalouf, Fadi, Macarayan, Erlyn Rachelle King, Mackay, Mark T, Maddison, Emilie R, Madotto, Fabiana, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Mohammed, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malhotra, Rajesh, Malta, Deborah Carvalho, Mamun, Abdullah A, Manhertz, Trey, Manguerra, Helena, Mansournia, Mohammad Ali, Mantovani, Lorenzo G, Manyazewal, Tsegahun, Mapoma, Chabila C, Margono, Christopher, Martinez-Raga, Jose, Martins, Sheila Cristina Ouriques, Martins-Melo, Francisco Rogerlândio, Martopullo, Ira, März, Winfried, Massenburg, Benjamin Ballard, Mathur, Manu Raj, Maulik, Pallab K, Mazidi, Mohsen, McAlinden, Colm, McGrath, John J, McKee, Martin, Mehata, Suresh, Mehrotra, Ravi, Mehta, Kala M, Mehta, Varshil, Meier, Toni, Mejia-Rodriguez, Fabiola, Meles, Kidanu Gebremariam, Melku, Mulugeta, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Mengiste, Degu Abate, Mengistu, Desalegn Tadese, Menota, Bereket Gebremichael, Mensah, George A, Meretoja, Atte, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Miazgowski, Tomasz, Micha, Renata, Milam, Robert, Millear, Anoushka, Miller, Ted R, Mini, GK, Minnig, Shawn, Mirica, Andreea, Mirrakhimov, Erkin M, Misganaw, Awoke, Mitchell, Philip B, Mlashu, Fitsum Weldegebreal, Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammadibakhsh, Roghayeh, Mohammed, Ebrahim, Mohammed, Mohammed A, Mohammed, Shafiu, Mokdad, Ali H, Mola, Glen Liddell, Molokhia, Mariam, Momeniha, Fatemeh, Monasta, Lorenzo, Montañez Hernandez, Julio Cesar, Moosazadeh, Mahmood, Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Moreno Velasquez, Ilais, Mori, Rintaro, Morrison, Shane D, Moses, Mark, Mousavi, Seyyed Meysam, Mueller, Ulrich O, Murhekar, Manoj, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Srinivas, Musa, Jonah, Musa, Kamarul Imran, Mustafa, Ghulam, Muthupandian, Saravanan, Nagata, Chie, Nagel, Gabriele, Naghavi, Mohsen, Naheed, Aliya, Naik, Gurudatta A, Naik, Nitish, Najafi, 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Patle, Ajay, Patton, George C, Paturi, Vishnupriya Rao, Paudel, Deepak, Pedroso, Marcel de Moares, Pedroza, Sandra P, Pereira, David M, Perico, Norberto, Peterson, Hannah, Petzold, Max, Peykari, Niloofar, Phillips, Michael Robert, Piel, Frédéric B, Pigott, David M, Pillay, Julian David, Piradov, Michael A, Polinder, Suzanne, Pond, Constance D, Postma, Maarten J, Pourmalek, Farshad, Prakash, Swayam, Prasad, Narayan, Prasad, Noela Marie, Purcell, Caroline, Qorbani, Mostafa, Quintana, Hedley Knewjen, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahimi, Kazem, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rahman, Sajjad Ur, Rai, Rajesh Kumar, Raju, Sree Bhushan, Ram, Usha, Rana, Saleem M, Rankin, Zane, Rasella, Davide, Rawaf, David Laith, Rawaf, Salman, Ray, Sarah E, Razo-García, Christian Aspacia, Reddy, Priscilla, Reiner, Robert C, Reis, Cesar, Reitsma, Marissa B, Remuzzi, Giuseppe, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Satar, Rezai, Mohammad Sadegh, Ribeiro, Antonio L, Rios Blancas, Maria Jesus, Rivera, Juan A, Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A, Rothenbacher, Dietrich, Roy, Ambuj, Roy, Nobhojit, Ruhago, George Mugambage, Sabde, Yogesh Damodar, Sachdev, Perminder S, Sadat, Nafis, Safdarian, Mahdi, Safiri, Saeid, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, Haniye Sadat, Salama, Joseph, Salamati, Payman, Saldanha, Raphael de Freitas, Salimzadeh, Hamideh, Salomon, Joshua A, Samy, Abdallah M, Sanabria, Juan Ramon, Sancheti, Parag K, Sanchez-Niño, Maria Dolores, Santomauro, Damian, Santos, Itamar S, Santric Milicevic, Milena M, Sarker, Abdur Razzaque, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Saxena, Sonia, Saylan, Mete I, Schaeffner, Elke, Schmidhuber, Josef, Schmidt, Maria Inês, Schneider, Ione J C, Schumacher, Austin E, Schutte, Aletta E, Schwebel, David C, Schwendicke, Falk, Sekerija, Mario, 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Sayed, Zaman, Sojib Bin, Zamani, Mohammad, Zenebe, Zerihun Menlkalew, Zhou, Maigeng, Zhu, Jun, Zimsen, Stephanie R M, Zipkin, Ben, Zodpey, Sanjay, Zuhlke, Liesl Joanna, Murray, Christopher J L, and Lozano, Rafael
- Abstract
Background: A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016. Methods: Drawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0–100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best); we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0–100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derive
- Published
- 2018
24. Long‐Term Use of Proton Pump Inhibitors and Community‐Acquired Pneumonia: Adverse Effect or Bias?
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Ayele, Henok Tadesse, primary, Dormuth, Colin R., additional, and Filion, Kristian B., additional
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- 2018
- Full Text
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25. Effect of isoniazid preventive therapy on tuberculosis or death in persons with HIV : a retrospective cohort study
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Ayele, Henok Tadesse, van Mourik, Maaike S M, Bonten, Marc J M, Ayele, Henok Tadesse, van Mourik, Maaike S M, and Bonten, Marc J M
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- 2015
26. Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults : A Systematic Review and Meta-Analysis of Randomized Trials
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Ayele, Henok Tadesse, Mourik, Maaike S M van, Debray, Thomas P A, Bonten, Marc J M, Ayele, Henok Tadesse, Mourik, Maaike S M van, Debray, Thomas P A, and Bonten, Marc J M
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- 2015
27. Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults: A Systematic Review and Meta-Analysis of Randomized Trials
- Author
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Epi Infectieziekten, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, Epi Infectieziekten Team 1, Epi Methoden Team 1, Circulatory Health, Ayele, Henok Tadesse, Mourik, Maaike S M van, Debray, Thomas P A, Bonten, Marc J M, Epi Infectieziekten, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, Epi Infectieziekten Team 1, Epi Methoden Team 1, Circulatory Health, Ayele, Henok Tadesse, Mourik, Maaike S M van, Debray, Thomas P A, and Bonten, Marc J M
- Published
- 2015
28. Effect of isoniazid preventive therapy on tuberculosis or death in persons with HIV: a retrospective cohort study
- Author
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Infection & Immunity, JC onderzoeksprogramma Infectieziekten, MMB, Epi Infectieziekten Team 1, MMB Research line 2, Ayele, Henok Tadesse, van Mourik, Maaike S M, Bonten, Marc J M, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, MMB, Epi Infectieziekten Team 1, MMB Research line 2, Ayele, Henok Tadesse, van Mourik, Maaike S M, and Bonten, Marc J M
- Published
- 2015
29. Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults: A Systematic Review and Meta-Analysis of Randomized Trials
- Author
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Ayele, Henok Tadesse, primary, Mourik, Maaike S. M. van, additional, Debray, Thomas P. A., additional, and Bonten, Marc J. M., additional
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- 2015
- Full Text
- View/download PDF
30. Effect of isoniazid preventive therapy on tuberculosis or death in persons with HIV: a retrospective cohort study
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Ayele, Henok Tadesse, primary, van Mourik, Maaike SM, additional, and Bonten, Marc JM, additional
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- 2015
- Full Text
- View/download PDF
31. Work Factors and Commitment of Public Health Care Providers, in Oromiya Region, Ethiopia/2010: The Case of Equity and Extrinsic Factors
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Bune, Girma Tenkolu, primary, Tesfaye, Solomon Hailemariam, additional, Ayele, Henok Tadesse, additional, and Zerfu, Tadesse Alemu, additional
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- 2014
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32. Malnutrition: Prevalence and its associated factors in People living with HIV/AIDS, in Dilla University Referral Hospital
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Hailemariam, Solomon, primary, Bune, Girma Tenkolu, additional, and Ayele, Henok Tadesse, additional
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- 2013
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33. Alcohol use and burden for 195 countries and territories, 1990-2016 : a systematic analysis for the Global Burden of Disease Study 2016
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Uthman, Olalekan A, Valdez, Pascual R, Van Boven, Job F M, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yuan-Pang, Weiderpass, Elisabete, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Widecka, Justyna, Wijeratne, Tissa, Wyper, Grant M A, Xu, Gelin, Yamada, Tomohide, Yano, Yuichiro, Ye, Pengpeng, Yimer, Ebrahim M, Yip, Paul, Yirsaw, Biruck Desalegn, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Zachariah, Geevar, Zaidi, Zoubida, Zamani, Mohammad, Zhang, Xueying, Zodpey, Sanjay, Mokdad, Ali H, Naghavi, Mohsen, Griswold, Max G, Fullman, Nancy, Hawley, Caitlin, Arian, Nicholas, Zimsen, Stephanie R M, Tymeson, Hayley D, Venkateswaran, Vidhya, Tapp, Austin Douglas, Forouzanfar, Mohammad H, Salama, Joseph S, Abate, Kalkidan Hassen, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abdulkader, Rizwan Suliankatchi, Abebe, Zegeye, Aboyans, Victor, Abrar, Mohammed Mehdi, Acharya, Pawan, Adetokunboh, Olatunji O, Adhikari, Tara Ballav, Adsuar, Jose C, Afarideh, Mohsen, Agardh, Emilie Elisabet, Agarwal, Gina, Aghayan, Sargis Aghasi, Agrawal, Sutapa, Ahmed, Muktar Beshir, Akibu, Mohammed, Akinyemiju, Tomi, Akseer, Nadia, Asfoor, Deena H Al, Al-Aly, Ziyad, Alahdab, Fares, Alam, Khurshid, Albujeer, Ammar, Alene, Kefyalew Addis, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F, Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H, Basaleem, Huda, Baye, Estifanos, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Béjot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A, Bensenor, Isabela M, Bernabe, Eduardo, Bernstein, Robert S, Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bililign, Nigus, Birlik, Sait Mentes, Birungi, Charles, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjørge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, Soufiane, Bragazzi, Nicola Luigi, Brenner, Hermann, Butt, Zahid A, Cahuana-Hurtado, Lucero, Calabria, Bianca, Campos-Nonato, Ismael R, Campuzano, Julio Cesar, Carreras, Giulia, Carrero, Juan J, Carvalho, Félix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Catalá-López, Ferrán, Chang, Jung-Chen, Charlson, Fiona J, Chattopadhyay, Aparajita, Chaturvedi, Pankaj, Chowdhury, Rajiv, Christopher, Devasahayam J, Chung, Sheng-Chia, Ciobanu, Liliana G, Claro, Rafael M, Conti, Sara, Cousin, Ewerton, Criqui, Michael H, Dachew, Berihun Assefa, Dargan, Paul I, Daryani, Ahmad, Das Neves, José, Davletov, Kairat, De Castro, Filipa, De Courten, Barbora, De Neve, Jan-Walter, Degenhardt, Louisa, Demoz, Gebre Teklemariam, Des Jarlais, Don C, Dey, Subhojit, Dhaliwal, Rupinder Singh, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Doku, David Teye, Doyle, Kerrie E, Dubey, Manisha, Dubljanin, Eleonora, Duncan, Bruce B, Ebrahimi, Hedyeh, Edessa, Dumessa, El Sayed Zaki, Maysaa, Ermakov, Sergei Petrovich, Erskine, Holly E, Esteghamati, Alireza, Faramarzi, Mahbobeh, Farioli, Andrea, Faro, Andre, Farvid, Maryam S, Farzadfar, Farshad, Feigin, Valery L, Felisbino-Mendes, Mariana Santos, Fernandes, Eduarda, Ferrari, Alize J, Ferri, Cleusa P, Fijabi, Daniel Obadare, Filip, Irina, Finger, Jonas David, Fischer, Florian, Flaxman, Abraham D, Franklin, Richard Charles, Futran, Neal D, Gallus, Silvano, Ganji, Morsaleh, Gankpe, Fortune Gbetoho, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M, Ghadimi, Reza, Ghandour, Lilian A, Ghimire, Mamata, Gill, Paramjit Singh, Ginawi, Ibrahim Abdelmageed, Giref, Ababi Zergaw Z, Gona, Philimon N, Gopalani, Sameer Vali, Gotay, Carolyn C, Goulart, Alessandra C, Greaves, Felix, Grosso, Giuseppe, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Gutiérrez, Reyna Alma, GVS, Murthy, Hafezi-Nejad, Nima, Hagos, Tekleberhan Beyene, Hailu, Gessessew Bugssa, Hamadeh, Randah R, Hankey, Graeme J, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hay, Simon I, Heibati, Behzad, Henok, Andualem, Heredia-Pi, Ileana, Hernández-Llanes, Norberto Francisco, Herteliu, Claudiu, Hibstu, Desalegn Ts Tsegaw, Hoogar, Praveen, Horita, Nobuyuki, Hosgood, H Dean, Hosseini, Mostafa, Hostiuc, Mihaela, Hu, Guoqing, Huang, Hsiang, Husseini, Abdullatif, Idrisov, Bulat, Ileanu, Bogdan Vasile, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Jackson, Maria D, Jakovljevic, Mihajlo, Jalu, Moti Tolera, Jayatilleke, Achala Upendra, Jha, Ravi Prakash, Jonas, Jost B, Jozwiak, Jacek Jerzy, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kapil, Umesh, Kasaeian, Amir, Kassa, Tesfaye D Dessale, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Kebede, Seifu, Kefale, Adane Teshome, Keiyoro, Peter Njenga, Kengne, Andre Pascal, Khader, Yousef, Khafaie, Morteza Abdullatif, Khalil, Ibrahim A, Khan, Md Nuruzzaman, Khang, Young-Ho, Khater, Mona M, Khubchandani, Jagdish, Kim, Cho-Il, Kim, Daniel, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kivimäki, Mika, Kochhar, Sonali, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Krishan, Kewal, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kulkarni, Veena S, Kumar, Pushpendra, Lafranconi, Alessandra, Lakshmana Balaji, Arjun, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lami, Faris Hasan, Lan, Qing, Lang, Justin J, Lansky, Sonia, Larsson, Anders O, Latifi, Arman, Leasher, Janet L, Lee, Paul H, Leigh, James, Leinsalu, Mall, Leung, Janni, Levi, Miriam, Li, Yichong, Lim, Lee-Ling, Lobato-Cordero, Andrea, Lopez, Alan D, Lotufo, Paulo A, Macarayan, Erlyn Rachelle King, Machado, Isis Eloah, Madotto, Fabiana, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malta, Deborah Carvalho, Mapoma, Chabila Christopher, Martinez-Raga, Jose, Maulik, Pallab K, Mazidi, Mohsen, Mckee, Martin, Mehta, Varshil, Meier, Toni, Mekonen, Tesfa, Meles, Kidanu Gebremariam, Melese, Addisu, Memiah, Peter T N, Mendoza, Walter, Mengistu, Desalegn Tadese, Mensah, George A, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Miazgowski, Tomasz, Miller, Ted R, Mini, Gk, Mirica, Andreea, Mirrakhimov, Erkin M, Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammadifard, Noushin, Mohammed, Shafiu, Monasta, Lorenzo, Moraga, Paula, Morawska, Lidia, Mousavi, Seyyed Meysam, Mukhopadhyay, Satinath, Musa, Kamarul Imran, Naheed, Aliya, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nansseu, Jobert Richie, Nayak, Mudavath Siva Durga Prasad, Nejjari, Chakib, Neupane, Subas, Neupane, Sudan Prasad, Ngunjiri, Josephine W, Nguyen, Cuong Tat, Nguyen, Long Hoang, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Noubiap, Jean Jacques, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oommen, Anu Mary, Oren, Eyal, Orpana, Heather M, Ortega-Altamirano, Doris D V, Ortiz, Justin R, Ota, Erika, Owolabi, Mayowa Ojo, Oyekale, Abayomi Samuel, P A, Mahesh, Pana, Adrian, Park, Eun-Kee, Parry, Charles D H, Parsian, Hadi, Patle, Ajay, Patton, George C, Paudel, Deepak, Petzold, Max, Phillips, Michael R, Pillay, Julian David, Postma, Maarten J, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Rajsic, Sasa, Raju, Sree Bhushan, Ram, Usha, Rana, Saleem M, Ranabhat, Chhabi Lal, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C, Reis, Cesar, Renzaho, Andre M N, Rezai, Mohammad Sadegh, Roever, Leonardo, Ronfani, Luca, Room, Robin, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A, Roy, Ambuj, Sabde, Yogesh Damodar, Saddik, Basema, Safiri, Saeid, Sahebkar, Amirhossein, Saleem, Zikria, Salomon, Joshua A, Salvi, Sundeep Santosh, Sanabria, Juan, Sanchez-Niño, Maria Dolores, Santomauro, Damian Francesco, Santos, Itamar S, Santric Milicevic, Milena M M, Sarker, Abdur Razzaque, Sarmiento-Suárez, Rodrigo, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete, Schaub, Michael P, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta Elisabeth, Schwendicke, Falk, Sepanlou, Sadaf G, Shaikh, Masood Ali, Sharif, Mehdi, She, Jun, Sheikh, Aziz, Shen, Jiabin, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shukla, Sharvari Rahul, Sigfusdottir, Inga Dora, Silva, Diego Augusto Santos, Silva, Natacha Torres Da, Silveira, Dayane Gabriele Alves, Sinha, Dhirendra Narain, Sitas, Freddy, Soares Filho, Adauto Martins, Soofi, Moslem, Sorensen, Reed J D, Soriano, Joan B, Sreeramareddy, Chandrashekhar T, Steckling, Nadine, Stein, Dan J, Sufiyan, Mu'awiyyah Babale, Sur, Patrick J, Sykes, Bryan L, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tavakkoli, Mohammad, Tehrani-Banihashemi, Arash, Tekle, Merhawi Gebremedhin, Thapa, Subash, Thomas, Nihal, Topor-Madry, Roman, Topouzis, Fotis, Tran, Bach Xuan, Troeger, Christopher E, Truelsen, Thomas Clement, Tsilimparis, Nikolaos, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Murray, Christopher J L, Gakidou, Emmanuela, Griswold, M, Fullman, N, Hawley, C, Arian, N, Zimsen, S, Tymeson, H, Venkateswaran, V, Tapp, A, Forouzanfar, M, Salama, J, Abate, K, Abate, D, Abay, S, Abbafati, C, Abdulkader, R, Abebe, Z, Aboyans, V, Abrar, M, Acharya, P, Adetokunboh, O, Adhikari, T, Adsuar, J, Afarideh, M, Agardh, E, Agarwal, G, Aghayan, S, Agrawal, S, Ahmed, M, Akibu, M, Akinyemiju, T, Akseer, N, Asfoor, D, Al-Aly, Z, Alahdab, F, Alam, K, Albujeer, A, Alene, K, Ali, R, Ali, S, Alijanzadeh, M, Aljunid, S, Alkerwi, A, Allebeck, P, Alvis-Guzman, N, Amare, A, Aminde, L, Ammar, W, Amoako, Y, Amul, G, Andrei, C, Angus, C, Ansha, M, Antonio, C, Aremu, O, Ärnlöv, J, Artaman, A, Aryal, K, Assadi, R, Ausloos, M, Avila-Burgos, L, Avokpaho, E, Awasthi, A, Ayele, H, Ayer, R, Ayuk, T, Azzopardi, P, Badali, H, Badawi, A, Banach, M, Barker-Collo, S, Barrero, L, Basaleem, H, Baye, E, Bazargan-Hejazi, S, Bedi, N, Béjot, Y, Belachew, A, Belay, S, Bennett, D, Bensenor, I, Bernabe, E, Bernstein, R, Beyene, A, Beyranvand, T, Bhaumik, S, Bhutta, Z, Biadgo, B, Bijani, A, Bililign, N, Birlik, S, Birungi, C, Bizuneh, H, Bjerregaard, P, Bjørge, T, Borges, G, Bosetti, C, Boufous, S, Bragazzi, N, Brenner, H, Butt, Z, Cahuana-Hurtado, L, Calabria, B, Campos-Nonato, I, Campuzano, J, Carreras, G, Carrero, J, Carvalho, F, Castañeda-Orjuela, C, Castillo Rivas, J, Catalá-López, F, Chang, J, Charlson, F, Chattopadhyay, A, Chaturvedi, P, Chowdhury, R, Christopher, D, Chung, S, Ciobanu, L, Claro, R, Conti, S, Cousin, E, Criqui, M, Dachew, B, Dargan, P, Daryani, A, Das Neves, J, Davletov, K, De Castro, F, De Courten, B, De Neve, J, Degenhardt, L, Demoz, G, Des Jarlais, D, Dey, S, Dhaliwal, R, Dharmaratne, S, Dhimal, M, Doku, D, Doyle, K, Dubey, M, Dubljanin, E, Duncan, B, Ebrahimi, H, Edessa, D, El Sayed Zaki, M, Ermakov, S, Erskine, H, Esteghamati, A, Faramarzi, M, Farioli, A, Faro, A, Farvid, M, Farzadfar, F, Feigin, V, Felisbino-Mendes, M, Fernandes, E, Ferrari, A, Ferri, C, Fijabi, D, Filip, I, Finger, J, Fischer, F, Flaxman, A, Franklin, R, Futran, N, Gallus, S, Ganji, M, Gankpe, F, Gebregergs, G, Gebrehiwot, T, Geleijnse, J, Ghadimi, R, Ghandour, L, Ghimire, M, Gill, P, Ginawi, I, Giref, A, Gona, P, Gopalani, S, Gotay, C, Goulart, A, Greaves, F, Grosso, G, Guo, Y, Gupta, R, Gupta, V, Gutiérrez, R, Gvs, M, Hafezi-Nejad, N, Hagos, T, Hailu, G, Hamadeh, R, Hamidi, S, Hankey, G, Harb, H, Harikrishnan, S, Haro, J, Hassen, H, Havmoeller, R, Hay, S, Heibati, B, Henok, A, Heredia-Pi, I, Hernández-Llanes, N, Herteliu, C, Hibstu, D, Hoogar, P, Horita, N, Hosgood, H, Hosseini, M, Hostiuc, M, Hu, G, Huang, H, Husseini, A, Idrisov, B, Ileanu, B, Ilesanmi, O, Irvani, S, Islam, S, Jackson, M, Jakovljevic, M, Jalu, M, Jayatilleke, A, Jha, R, Jonas, J, Jozwiak, J, Kabir, Z, Kadel, R, Kahsay, A, Kapil, U, Kasaeian, A, Kassa, T, Katikireddi, S, Kawakami, N, Kebede, S, Kefale, A, Keiyoro, P, Kengne, A, Khader, Y, Khafaie, M, Khalil, I, Khan, M, Khang, Y, Khater, M, Khubchandani, J, Kim, C, Kim, D, Kim, Y, Kimokoti, R, Kisa, A, Kivimäki, M, Kochhar, S, Kosen, S, Koul, P, Koyanagi, A, Krishan, K, Kuate Defo, B, Kucuk Bicer, B, Kulkarni, V, Kumar, P, Lafranconi, A, Lakshmana Balaji, A, Lalloo, R, Lallukka, T, Lam, H, Lami, F, Lan, Q, Lang, J, Lansky, S, Larsson, A, Latifi, A, Leasher, J, Lee, P, Leigh, J, Leinsalu, M, Leung, J, Levi, M, Li, Y, Lim, L, Linn, S, Liu, S, Lobato-Cordero, A, Lopez, A, Lotufo, P, Macarayan, E, Machado, I, Madotto, F, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Majdan, M, Majdzadeh, R, Majeed, A, Malekzadeh, R, Malta, D, Mapoma, C, Martinez-Raga, J, Maulik, P, Mazidi, M, Mckee, M, Mehta, V, Meier, T, Mekonen, T, Meles, K, Melese, A, Memiah, P, Mendoza, W, Mengistu, D, Mensah, G, Meretoja, T, Mezgebe, H, Miazgowski, T, Miller, T, Mini, G, Mirica, A, Mirrakhimov, E, Moazen, B, Mohammad, K, Mohammadifard, N, Mohammed, S, Monasta, L, Moraga, P, Morawska, L, Mousavi, S, Mukhopadhyay, S, Musa, K, Naheed, A, Naik, G, Najafi, F, Nangia, V, Nansseu, J, Nayak, M, Nejjari, C, Neupane, S, Ngunjiri, J, Nguyen, C, Nguyen, L, Nguyen, T, Ningrum, D, Nirayo, Y, Noubiap, J, Ofori-Asenso, R, Ogbo, F, Oh, I, Oladimeji, O, Olagunju, A, Olivares, P, Olusanya, B, Olusanya, J, Oommen, A, Oren, E, Orpana, H, Ortega-Altamirano, D, Ortiz, J, Ota, E, Owolabi, M, Oyekale, A, P A, M, Pana, A, Park, E, Parry, C, Parsian, H, Patle, A, Patton, G, Paudel, D, Petzold, M, Phillips, M, Pillay, J, Postma, M, Pourmalek, F, Prabhakaran, D, Qorbani, M, Radfar, A, Rafay, A, Rafiei, A, Rahim, F, Rahimi-Movaghar, A, Rahman, M, Rai, R, Rajsic, S, Raju, S, Ram, U, Rana, S, Ranabhat, C, Rawaf, D, Rawaf, S, Reiner, R, Reis, C, Renzaho, A, Rezai, M, Roever, L, Ronfani, L, Room, R, Roshandel, G, Rostami, A, Roth, G, Roy, A, Sabde, Y, Saddik, B, Safiri, S, Sahebkar, A, Saleem, Z, Salomon, J, Salvi, S, Sanabria, J, Sanchez-Niño, M, Santomauro, D, Santos, I, Santric Milicevic, M, Sarker, A, Sarmiento-Suárez, R, Sarrafzadegan, N, Sartorius, B, Satpathy, M, Sawhney, M, Saxena, S, Saylan, M, Schaub, M, Schmidt, M, Schneider, I, Schöttker, B, Schutte, A, Schwendicke, F, Sepanlou, S, Shaikh, M, Sharif, M, She, J, Sheikh, A, Shen, J, Shiferaw, M, Shigematsu, M, Shiri, R, Shishani, K, Shiue, I, Shukla, S, Sigfusdottir, I, Silva, D, Silva, N, Silveira, D, Sinha, D, Sitas, F, Soares Filho, A, Soofi, M, Sorensen, R, Soriano, J, Sreeramareddy, C, Steckling, N, Stein, D, Sufiyan, M, Sur, P, Sykes, B, Tabarés-Seisdedos, R, Tabuchi, T, Tavakkoli, M, Tehrani-Banihashemi, A, Tekle, M, Thapa, S, Thomas, N, Topor-Madry, R, Topouzis, F, Tran, B, Troeger, C, Truelsen, T, Tsilimparis, N, Tyrovolas, S, Ukwaja, K, Ullah, I, Uthman, O, Valdez, P, Van Boven, J, Vasankari, T, Venketasubramanian, N, Violante, F, Vladimirov, S, Vlassov, V, Vollset, S, Vos, T, Wagnew, F, Waheed, Y, Wang, Y, Weiderpass, E, Weldegebreal, F, Weldegwergs, K, Werdecker, A, Westerman, R, Whiteford, H, Widecka, J, Wijeratne, T, Wyper, G, Xu, G, Yamada, T, Yano, Y, Ye, P, Yimer, E, Yip, P, Yirsaw, B, Yisma, E, Yonemoto, N, Yoon, S, Yotebieng, M, Younis, M, Zachariah, G, Zaidi, Z, Zamani, M, Zhang, X, Zodpey, S, Mokdad, A, Naghavi, M, Murray, C, Gakidou, E, Halk Sağlığı, GBD 2016 Alcohol Collaborators, Griswold, Max G, Fullman, Nancy, Hawley, Caitlin, Arian, Nichola, Zimsen, Stephanie R M, Tymeson, Hayley D, Venkateswaran, Vidhya, Tapp, Austin Dougla, Forouzanfar, Mohammad H, Salama, Joseph S, Abate, Kalkidan Hassen, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abdulkader, Rizwan Suliankatchi, Abebe, Zegeye, Aboyans, Victor, Abrar, Mohammed Mehdi, Acharya, Pawan, Adetokunboh, Olatunji O, Adhikari, Tara Ballav, Adsuar, Jose C, Afarideh, Mohsen, Agardh, Emilie Elisabet, Agarwal, Gina, Aghayan, Sargis Aghasi, Agrawal, Sutapa, Ahmed, Muktar Beshir, Akibu, Mohammed, Akinyemiju, Tomi, Akseer, Nadia, Asfoor, Deena H Al, Al-Aly, Ziyad, Alahdab, Fare, Alam, Khurshid, Albujeer, Ammar, Alene, Kefyalew Addi, Ali, Raghib, Ali, Syed Danish, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Allebeck, Peter, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Ammar, Walid, Amoako, Yaw Ampem, Amul, Gianna Gayle Herrera, Andrei, Catalina Liliana, Angus, Colin, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Assadi, Reza, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F, Awasthi, Ashish, Ayele, Henok Tadesse, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Banach, Maciej, Barker-Collo, Suzanne Lyn, Barrero, Lope H, Basaleem, Huda, Baye, Estifano, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Béjot, Yannick, Belachew, Abate Bekele, Belay, Saba Abraham, Bennett, Derrick A, Bensenor, Isabela M, Bernabe, Eduardo, Bernstein, Robert S, Beyene, Addisu Shunu, Beyranvand, Tina, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bililign, Nigu, Birlik, Sait Mente, Birungi, Charle, Bizuneh, Hailemichael, Bjerregaard, Peter, Bjørge, Tone, Borges, Guilherme, Bosetti, Cristina, Boufous, Soufiane, Bragazzi, Nicola Luigi, Brenner, Hermann, Butt, Zahid A, Cahuana-Hurtado, Lucero, Calabria, Bianca, Campos-Nonato, Ismael R, Campuzano, Julio Cesar, Carreras, Giulia, Carrero, Juan J, Carvalho, Félix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Catalá-López, Ferrán, Chang, Jung-Chen, Charlson, Fiona J, Chattopadhyay, Aparajita, Chaturvedi, Pankaj, Chowdhury, Rajiv, Christopher, Devasahayam J, Chung, Sheng-Chia, Ciobanu, Liliana G, Claro, Rafael M, Conti, Sara, Cousin, Ewerton, Criqui, Michael H, Dachew, Berihun Assefa, Dargan, Paul I, Daryani, Ahmad, Das Neves, José, Davletov, Kairat, De Castro, Filipa, De Courten, Barbora, De Neve, Jan-Walter, Degenhardt, Louisa, Demoz, Gebre Teklemariam, Des Jarlais, Don C, Dey, Subhojit, Dhaliwal, Rupinder Singh, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Doku, David Teye, Doyle, Kerrie E, Dubey, Manisha, Dubljanin, Eleonora, Duncan, Bruce B, Ebrahimi, Hedyeh, Edessa, Dumessa, El Sayed Zaki, Maysaa, Ermakov, Sergei Petrovich, Erskine, Holly E, Esteghamati, Alireza, Faramarzi, Mahbobeh, Farioli, Andrea, Faro, Andre, Farvid, Maryam S, Farzadfar, Farshad, Feigin, Valery L, Felisbino-Mendes, Mariana Santo, Fernandes, Eduarda, Ferrari, Alize J, Ferri, Cleusa P, Fijabi, Daniel Obadare, Filip, Irina, Finger, Jonas David, Fischer, Florian, Flaxman, Abraham D, Franklin, Richard Charle, Futran, Neal D, Gallus, Silvano, Ganji, Morsaleh, Gankpe, Fortune Gbetoho, Gebregergs, Gebremedhin Berhe, Gebrehiwot, Tsegaye Tewelde, Geleijnse, Johanna M, Ghadimi, Reza, Ghandour, Lilian A, Ghimire, Mamata, Gill, Paramjit Singh, Ginawi, Ibrahim Abdelmageed, Giref, Ababi Zergaw Z, Gona, Philimon N, Gopalani, Sameer Vali, Gotay, Carolyn C, Goulart, Alessandra C, Greaves, Felix, Grosso, Giuseppe, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Gutiérrez, Reyna Alma, GVS, Murthy, Hafezi-Nejad, Nima, Hagos, Tekleberhan Beyene, Hailu, Gessessew Bugssa, Hamadeh, Randah R, Hamidi, Samer, Hankey, Graeme J, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Hassen, Hamid Yimam, Havmoeller, Rasmu, Hay, Simon I, Heibati, Behzad, Henok, Andualem, Heredia-Pi, Ileana, Hernández-Llanes, Norberto Francisco, Herteliu, Claudiu, Hibstu, Desalegn Ts Tsegaw, Hoogar, Praveen, Horita, Nobuyuki, Hosgood, H Dean, Hosseini, Mostafa, Hostiuc, Mihaela, Hu, Guoqing, Huang, Hsiang, Husseini, Abdullatif, Idrisov, Bulat, Ileanu, Bogdan Vasile, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Jackson, Maria D, Jakovljevic, Mihajlo, Jalu, Moti Tolera, Jayatilleke, Achala Upendra, Jha, Ravi Prakash, Jonas, Jost B, Jozwiak, Jacek Jerzy, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kapil, Umesh, Kasaeian, Amir, Kassa, Tesfaye D Dessale, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Kebede, Seifu, Kefale, Adane Teshome, Keiyoro, Peter Njenga, Kengne, Andre Pascal, Khader, Yousef, Khafaie, Morteza Abdullatif, Khalil, Ibrahim A, Khan, Md Nuruzzaman, Khang, Young-Ho, Khater, Mona M, Khubchandani, Jagdish, Kim, Cho-Il, Kim, Daniel, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kivimäki, Mika, Kochhar, Sonali, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Krishan, Kewal, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kulkarni, Veena S, Kumar, Pushpendra, Lafranconi, Alessandra, Lakshmana Balaji, Arjun, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lami, Faris Hasan, Lan, Qing, Lang, Justin J, Lansky, Sonia, Larsson, Anders O, Latifi, Arman, Leasher, Janet L, Lee, Paul H, Leigh, Jame, Leinsalu, Mall, Leung, Janni, Levi, Miriam, Li, Yichong, Lim, Lee-Ling, Linn, Shai, Liu, Shiwei, Lobato-Cordero, Andrea, Lopez, Alan D, Lotufo, Paulo A, Macarayan, Erlyn Rachelle King, Machado, Isis Eloah, Madotto, Fabiana, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Majdan, Marek, Majdzadeh, Reza, Majeed, Azeem, Malekzadeh, Reza, Malta, Deborah Carvalho, Mapoma, Chabila Christopher, Martinez-Raga, Jose, Maulik, Pallab K, Mazidi, Mohsen, Mckee, Martin, Mehta, Varshil, Meier, Toni, Mekonen, Tesfa, Meles, Kidanu Gebremariam, Melese, Addisu, Memiah, Peter T N, Mendoza, Walter, Mengistu, Desalegn Tadese, Mensah, George A, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Miazgowski, Tomasz, Miller, Ted R, Mini, Gk, Mirica, Andreea, Mirrakhimov, Erkin M, Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammadifard, Noushin, Mohammed, Shafiu, Monasta, Lorenzo, Moraga, Paula, Morawska, Lidia, Mousavi, Seyyed Meysam, Mukhopadhyay, Satinath, Musa, Kamarul Imran, Naheed, Aliya, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nansseu, Jobert Richie, Nayak, Mudavath Siva Durga Prasad, Nejjari, Chakib, Neupane, Suba, Neupane, Sudan Prasad, Ngunjiri, Josephine W, Nguyen, Cuong Tat, Nguyen, Long Hoang, Nguyen, Trang Huyen, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Noubiap, Jean Jacque, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oommen, Anu Mary, Oren, Eyal, Orpana, Heather M, Ortega-Altamirano, Doris D V, Ortiz, Justin R, Ota, Erika, Owolabi, Mayowa Ojo, Oyekale, Abayomi Samuel, P A, Mahesh, Pana, Adrian, Park, Eun-Kee, Parry, Charles D H, Parsian, Hadi, Patle, Ajay, Patton, George C, Paudel, Deepak, Petzold, Max, Phillips, Michael R, Pillay, Julian David, Postma, Maarten J, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Rajsic, Sasa, Raju, Sree Bhushan, Ram, Usha, Rana, Saleem M, Ranabhat, Chhabi Lal, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C, Reis, Cesar, Renzaho, Andre M N, Rezai, Mohammad Sadegh, Roever, Leonardo, Ronfani, Luca, Room, Robin, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A, Roy, Ambuj, Sabde, Yogesh Damodar, Saddik, Basema, Safiri, Saeid, Sahebkar, Amirhossein, Saleem, Zikria, Salomon, Joshua A, Salvi, Sundeep Santosh, Sanabria, Juan, Sanchez-Niño, Maria Dolore, Santomauro, Damian Francesco, Santos, Itamar S, Santric Milicevic, Milena M M, Sarker, Abdur Razzaque, Sarmiento-Suárez, Rodrigo, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saxena, Sonia, Saylan, Mete, Schaub, Michael P, Schmidt, Maria Inê, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta Elisabeth, Schwendicke, Falk, Sepanlou, Sadaf G, Shaikh, Masood Ali, Sharif, Mehdi, She, Jun, Sheikh, Aziz, Shen, Jiabin, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shukla, Sharvari Rahul, Sigfusdottir, Inga Dora, Silva, Diego Augusto Santo, Silva, Natacha Torres Da, Silveira, Dayane Gabriele Alve, Sinha, Dhirendra Narain, Sitas, Freddy, Soares Filho, Adauto Martin, Soofi, Moslem, Sorensen, Reed J D, Soriano, Joan B, Sreeramareddy, Chandrashekhar T, Steckling, Nadine, Stein, Dan J, Sufiyan, Mu'awiyyah Babale, Sur, Patrick J, Sykes, Bryan L, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tavakkoli, Mohammad, Tehrani-Banihashemi, Arash, Tekle, Merhawi Gebremedhin, Thapa, Subash, Thomas, Nihal, Topor-Madry, Roman, Topouzis, Foti, Tran, Bach Xuan, Troeger, Christopher E, Truelsen, Thomas Clement, Tsilimparis, Nikolao, Tyrovolas, Stefano, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Uthman, Olalekan A, Valdez, Pascual R, Van Boven, Job F M, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yuan-Pang, Weiderpass, Elisabete, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Widecka, Justyna, Wijeratne, Tissa, Wyper, Grant M A, Xu, Gelin, Yamada, Tomohide, Yano, Yuichiro, Ye, Pengpeng, Yimer, Ebrahim M, Yip, Paul, Yirsaw, Biruck Desalegn, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Zachariah, Geevar, Zaidi, Zoubida, Zamani, Mohammad, Zhang, Xueying, Zodpey, Sanjay, Mokdad, Ali H, Naghavi, Mohsen, Murray, Christopher J L, and Gakidou, Emmanuela
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Adult ,Male ,Adolescent ,Alcohol Drinking ,Global Health ,Risk Assessment ,Global Burden of Disease ,Young Adult ,Age Distribution ,Retrospective Studie ,General & Internal Medicine ,Cause of Death ,Quality-Adjusted Life Year ,Prevalence ,Medicine (all) Alcohol GBD ,Sex Distribution ,Aged ,Aged, 80 and over ,Risk Factor ,Medicine (all) ,Commerce ,Middle Aged ,Observational Studies as Topic ,Prospective Studie ,Population Surveillance ,Female ,Human medicine ,Human - Abstract
Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods: Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings: Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age-standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks per week. Interpretation: Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that the risk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption. Funding: Bill & Melinda Gates Foundation.
34. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Troeger, Christopher, Blacker, Brigette, Khalil, Ibrahim A., Rao, Puja C., Cao, Jackie, Zimsen, Stephanie Rm, Albertson, Samuel B., Deshpande, Aniruddha, Farag, Tamer, Abebe, Zegeye, Adetifa, Ifedayo Morayo O., Adhikari, Tara Ballav, Akibu, Mohammed, Al Lami, Faris Hasan, Al-Eyadhy, Ayman, Alvis-Guzman, Nelson, Amare, Azmeraw T., Amoako, Yaw Ampem, Antonio, Carl Abelardo T., Aremu, Olatunde, Asfaw, Ephrem Tsegay, Asgedom, Solomon Weldegebreal, Atey, Tesfay Mehari, Attia, Engi Farouk, Avokpaho, Euripide Frinel G. Arthur, Ayele, Henok Tadesse, Ayuk, Tambe Betrand, Balakrishnan, Kalpana, Barac, Aleksandra, Bassat, Quique, Behzadifar, Masoud, Behzadifar, Meysam, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A., Bijani, Ali, Brauer, Michael, Brown, Alexandria, Camargos, Paulo Am, Castañeda-Orjuela, Carlos A., Colombara, Danny, Conti, Sara, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Do, Huyen Phuc, Dubljanin, Eleonora, Edessa, Dumessa, Elkout, Hajer, Endries, Aman Yesuf, Fijabi, Daniel Obadare, Foreman, Kyle J., Forouzanfar, Mohammad H., Fullman, Nancy, Garcia-Basteiro, Alberto L., Gessner, Bradford D., Gething, Peter W., Gupta, Rahul, Gupta, Tarun, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Hedayati, Mohammad T., Heidari, Mohsen, Hibstu, Desalegn Tsegaw, Horita, Nobuyuki, Ilesanmi, Olayinka S., Jakovljevic, Mihajlo B., Jamal, Amr A., Amaha Kahsay, Kasaeian, Amir, Kassa, Dessalegn Haile, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Md Nuruzzaman, Khang, Young-Ho, Kim, Yun Jin, Kissoon, Niranjan, Knibbs, Luke D., Kochhar, Sonali, Koul, Parvaiz A., Kumar, G. Anil, Lodha, Rakesh, Magdy Abd El Razek, Hassan, Malta, Deborah Carvalho, Mathew, Joseph L., Mengistu, Desalegn Tadese, Mezgebe, Haftay Berhane, Mohammad, Karzan Abdulmuhsin, Mohammed, Mohammed A., Momeniha, Fatemeh, Murthy, Srinivas, Nguyen, Cuong Tat, Nielsen, Katie R., Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Oren, Eyal, Ortiz, Justin R., Pa, Mahesh, Postma, Maarten J., Qorbani, Mostafa, Quansah, Reginald, Rai, Rajesh Kumar, Rana, Saleem M., Ranabhat, Chhabi Lal, Ray, Sarah E., Rezai, Mohammad Sadegh, Ruhago, George Mugambage, Safiri, Saeid, Salomon, Joshua A., Sartorius, Benn, Savic, Miloje, Sawhney, Monika, She, Jun, Sheikh, Aziz, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Singh, Jasvinder A., Somayaji, Ranjani, Stanaway, Jeffrey D., Sufiyan, Muawiyyah Babale, Taffere, Getachew Redae, Temsah, Mohamad-Hani, Thompson, Matthew J., Tobe-Gai, Ruoyan, Topor-Madry, Roman, Tran, Bach Xuan, Tran, Tung Thanh, Tuem, Kald Beshir, Ukwaja, Kingsley Nnanna, Vollset, Stein Emil, Walson, Judd L., Weldegebreal, Fitsum, Werdecker, Andrea, West, T. Eoin, Yonemoto, Naohiro, Zaki, Maysaa El Sayed, Zhou, Lei, Zodpey, Sanjay, Vos, Theo, Naghavi, Mohsen, Lim, Stephen S., Mokdad, Ali H., Murray, Christopher Jl, Hay, Simon I., Reiner, Robert C., Troeger, C, Blacker, B, Khalil, I, Rao, P, Cao, J, Zimsen, S, Albertson, S, Deshpande, A, Farag, T, Abebe, Z, Adetifa, I, Adhikari, T, Akibu, M, Al Lami, F, Al-Eyadhy, A, Alvis-Guzman, N, Amare, A, Amoako, Y, Antonio, C, Aremu, O, Asfaw, E, Asgedom, S, Atey, T, Attia, E, Avokpaho, E, Ayele, H, Ayuk, T, Balakrishnan, K, Barac, A, Bassat, Q, Behzadifar, M, Bhaumik, S, Bhutta, Z, Bijani, A, Brauer, M, Brown, A, Camargos, P, Castañeda-Orjuela, C, Colombara, D, Conti, S, Dadi, A, Dandona, L, Dandona, R, Do, H, Dubljanin, E, Edessa, D, Elkout, H, Endries, A, Fijabi, D, Foreman, K, Forouzanfar, M, Fullman, N, Garcia-Basteiro, A, Gessner, B, Gething, P, Gupta, R, Gupta, T, Hailu, G, Hassen, H, Hedayati, M, Heidari, M, Hibstu, D, Horita, N, Ilesanmi, O, Jakovljevic, M, Jamal, A, Kahsay, A, Kasaeian, A, Kassa, D, Khader, Y, Khan, E, Khan, M, Khang, Y, Kim, Y, Kissoon, N, Knibbs, L, Kochhar, S, Koul, P, Kumar, G, Lodha, R, Magdy Abd El Razek, H, Malta, D, Mathew, J, Mengistu, D, Mezgebe, H, Mohammad, K, Mohammed, M, Momeniha, F, Murthy, S, Nguyen, C, Nielsen, K, Ningrum, D, Nirayo, Y, Oren, E, Ortiz, J, Pa, M, Postma, M, Qorbani, M, Quansah, R, Rai, R, Rana, S, Ranabhat, C, Ray, S, Rezai, M, Ruhago, G, Safiri, S, Salomon, J, Sartorius, B, Savic, M, Sawhney, M, She, J, Sheikh, A, Shiferaw, M, Shigematsu, M, Singh, J, Somayaji, R, Stanaway, J, Sufiyan, M, Taffere, G, Temsah, M, Thompson, M, Tobe-Gai, R, Topor-Madry, R, Tran, B, Tran, T, Tuem, K, Ukwaja, K, Vollset, S, Walson, J, Weldegebreal, F, Werdecker, A, West, T, Yonemoto, N, Zaki, M, Zhou, L, Zodpey, S, Vos, T, Naghavi, M, Lim, S, Mokdad, A, Murray, C, Hay, S, Reiner, R, and Public Health
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Adult ,Male ,Adolescent ,Biostatistics ,Global Health ,Global Buren of Disease, Lower Respiratory Infections ,Article ,Global Burden of Disease ,Young Adult ,Cost of Illness ,Risk Factors ,Prevalence ,Humans ,Child ,Respiratory Tract Infections ,Aged ,Aged, 80 and over ,Incidence ,Infant, Newborn ,Infant ,Bacterial Infections ,Middle Aged ,Survival Analysis ,Virus Diseases ,Child, Preschool ,Female ,Topography, Medical ,Morbidity ,Epidemiologic Methods - Abstract
[Background] Lower respiratory infections are a leading cause of morbidity and mortality around the world. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, provides an up-to-date analysis of the burden of lower respiratory infections in 195 countries. This study assesses cases, deaths, and aetiologies spanning the past 26 years and shows how the burden of lower respiratory infection has changed in people of all ages. [Methods] We used three separate modelling strategies for lower respiratory infections in GBD 2016: a Bayesian hierarchical ensemble modelling platform (Cause of Death Ensemble model), which uses vital registration, verbal autopsy data, and surveillance system data to predict mortality due to lower respiratory infections; a compartmental meta-regression tool (DisMod-MR), which uses scientific literature, population representative surveys, and health-care data to predict incidence, prevalence, and mortality; and modelling of counterfactual estimates of the population attributable fraction of lower respiratory infection episodes due to Streptococcus pneumoniae, Haemophilus influenzae type b, influenza, and respiratory syncytial virus. We calculated each modelled estimate for each age, sex, year, and location. We modelled the exposure level in a population for a given risk factor using DisMod-MR and a spatio-temporal Gaussian process regression, and assessed the effectiveness of targeted interventions for each risk factor in children younger than 5 years. We also did a decomposition analysis of the change in LRI deaths from 2000–16 using the risk factors associated with LRI in GBD 2016. [Findings] In 2016, lower respiratory infections caused 652 572 deaths (95% uncertainty interval [UI] 586 475–720 612) in children younger than 5 years (under-5s), 1 080 958 deaths (943 749–1 170 638) in adults older than 70 years, and 2 377 697 deaths (2 145 584–2 512 809) in people of all ages, worldwide. Streptococcus pneumoniae was the leading cause of lower respiratory infection morbidity and mortality globally, contributing to more deaths than all other aetiologies combined in 2016 (1 189 937 deaths, 95% UI 690 445–1 770 660). Childhood wasting remains the leading risk factor for lower respiratory infection mortality among children younger than 5 years, responsible for 61·4% of lower respiratory infection deaths in 2016 (95% UI 45·7–69·6). Interventions to improve wasting, household air pollution, ambient particulate matter pollution, and expanded antibiotic use could avert one under-5 death due to lower respiratory infection for every 4000 children treated in the countries with the highest lower respiratory infection burden. [Interpretation] Our findings show substantial progress in the reduction of lower respiratory infection burden, but this progress has not been equal across locations, has been driven by decreases in several primary risk factors, and might require more effort among elderly adults. By highlighting regions and populations with the highest burden, and the risk factors that could have the greatest effect, funders, policy makers, and programme implementers can more effectively reduce lower respiratory infections among the world's most susceptible populations. [Findings] Bill & Melinda Gates Foundation.
35. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
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Lozano, Rafael, Fullman, Nancy, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdel-Rahman, Omar, Abdi, Alireza, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Nebiyu Dereje, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F, Abil, Olifan Zewdie, Aboyans, Victor, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Abu-Rmeileh, Niveen Me, Abyu, Gebre Y, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Acharya, Pawan, Adamu, Abdu A, Adebayo, Oladimeji M, Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O, Adhena, Beyene Meressa, Adhikari, Tara Ballav, Adib, Mina G, Adou, Arsène Kouablan, Adsuar, Jose C, Afarideh, Mohsen, Afshari, Mahdi, Afshin, Ashkan, Agarwal, Gina, Aghayan, Sargis Aghasi, Agius, Dominic, Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmed, Muktar Beshir, 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8. Economic growth ,1. No poverty ,10. No inequality ,3. Good health
36. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017
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Hamid Reza, Nourollahpour Shiadeh, Malihe, Nowroozi, Mohammad Reza, Nsoesie, Elaine O, Nyasulu, Peter S, Ofori-Asenso, Richard, Ogah, Okechukwu Samuel, Ogbo, Felix Akpojene, Oh, In-Hwan, Okoro, Anselm, Oladimeji, Olanrewaju, Olagunju, Andrew T, Olagunju, Tinuke O, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Ong, Sok King, Opio, John Nelson, Oren, Eyal, Ortiz, Justin R, Ortiz, Alberto, Ota, Erika, Otstavnov, Stanislav S, Øverland, Simon, Owolabi, Mayowa Ojo, Oyekale, Abayomi Samuel, P A, Mahesh, Pacella, Rosana, Pakhale, Smita, Pakhare, Abhijit P, Pana, Adrian, Panda, Basant Kumar, Panda-Jonas, Songhomitra, Pandey, Achyut Raj, Pandian, Jeyaraj Durai, Parisi, Andrea, Park, Eun-Kee, Parry, Charles D H, Parsian, Hadi, Patel, Shanti, Patle, Ajay, Patten, Scott B, Patton, George C, Paudel, Deepak, Pearce, Neil, Peprah, Emmanuel K, Pereira, Alexandre, Pereira, David M, Perez, Krystle M, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Petri, William A, 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Mohammad Sadegh, Riahi, Seyed Mohammad, Ribeiro, Antonio Luiz P, Riojas, Horacio, Rios-Blancas, Maria Jesus, Roba, Kedir Teji, Robinson, Stephen R, Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Roshchin, Denis O, Rostami, Ali, Rothenbacher, Dietrich, Rubagotti, Enrico, Ruhago, George Mugambage, Saadat, Soheil, Sabde, Yogesh Damodar, Sachdev, Perminder S, Saddik, Basema, Sadeghi, Ehsan, Moghaddam, Sahar Saeedi, Safari, Hosein, Safari, Yahya, Safari-Faramani, Roya, Safdarian, Mahdi, Safi, Sare, Safiri, Saeid, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, Haniye Sadat, Salahshoor, Mohamadreza, Salam, Nasir, Salama, Joseph S, Salamati, Payman, Saldanha, Raphael de Freitas, Salimi, Yahya, Salimzadeh, Hamideh, Salz, Inbal, Sambala, Evanson Zondani, Samy, Abdallah M, Sanabria, Juan, Sanchez-Niño, Maria Dolores, Santos, Itamar S, Santos, João Vasco, Santric Milicevic, Milena M, Sao Jose, Bruno Piassi, Sardana, Mayank, Sarker, Abdur Razzaque, Sarrafzadegan, Nizal, Sartorius, Benn, Sarvi, Shahabeddin, Sathian, Brijesh, Satpathy, Maheswar, Savic, Miloje, Sawant, Arundhati R, Sawhney, Monika, Saxena, Sonia, Sayyah, Mehdi, Scaria, Vinod, Schaeffner, Elke, Schelonka, Kathryn, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta Elisabeth, Schwebel, David C, Schwendicke, Falk, Scott, James G, Sekerija, Mario, Sepanlou, Sadaf G, Serván-Mori, Edson, Shabaninejad, Hosein, Shackelford, Katya Anne, Shafieesabet, Azadeh, Shaheen, Amira A, Shaikh, Masood Ali, Shakir, Raad A, Shams-Beyranvand, Mehran, Shamsi, MohammadBagher, Shamsizadeh, Morteza, Sharafi, Heidar, Sharafi, Kiomars, Sharif, Mehdi, Sharif-Alhoseini, Mahdi, Sharma, Meenakshi, Sharma, Jayendra, Sharma, Rajesh, She, Jun, Sheikh, Aziz, Sheth, Kevin N, Shi, Peilin, Shibuya, Kenji, Shifa, Girma Temam, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shirkoohi, Reza, Shiue, Ivy, Shokraneh, Farhad, Shrime, Mark G, Shukla, Sharvari Rahul, Si, Si, Siabani, Soraya, Siddiqi, Tariq J, Sigfusdottir, Inga Dora, Sigurvinsdottir, Rannveig, Silpakit, Naris, Silva, Diego Augusto Santos, Silva, João Pedro, Silveira, Dayane Gabriele Alves, Singam, Narayana Sarma Venkata, Singh, Jasvinder A, Singh, Virendra, Sinha, Anju Pradhan, Sinha, Dhirendra Narain, Sitas, Freddy, Skirbekk, Vegard, Sliwa, Karen, Soares Filho, Adauto Martins, Sobaih, Badr Hasan, Sobhani, Soheila, Soofi, Moslem, Soriano, Joan B, Soyiri, Ireneous N, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Srinivasan, Vinay, Srivastava, Rakesh Kumar, Starodubov, Vladimir I, Stathopoulou, Vasiliki, Steel, Nicholas, Stein, Dan J, Steiner, Caitlyn, Stewart, Leo G, Stokes, Mark A, Sudaryanto, Agus, Sufiyan, Mu'awiyyah Babale, Sulo, Gerhard, Sunguya, Bruno F, Sur, Patrick John, Sutradhar, Ipsita, Sykes, Bryan L, Sylaja, P N, Sylte, Dillon O, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tadakamadla, Santosh Kumar, Takahashi, Ken, Tandon, Nikhil, Tassew, Aberash Abay, Tassew, Segen Gebremeskel, Tavakkoli, Mohammad, Taveira, Nuno, Tawye, Nega Yimer, Tehrani-Banihashemi, Arash, Tekalign, Tigist Gashaw, Tekle, Merhawi Gebremedhin, Temesgen, Habtamu, Temsah, Mohamad-Hani, Temsah, Omar, Terkawi, Abdullah Sulieman, Teshale, Manaye Yihune, Tessema, Belay, Teweldemedhin, Mebrahtu, Thakur, Jarnail Singh, Thankappan, Kavumpurathu Raman, Thirunavukkarasu, Sathish, Thomas, Laura Anne, Thomas, Nihal, Thrift, Amanda G, Tilahun, Binyam, To, Quyen G, Tobe-Gai, Ruoyan, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Torre, Anna E, Tortajada-Girbés, Miguel, Tovani-Palone, Marcos Roberto, Towbin, Jeffrey A, Tran, Bach Xuan, Tran, Khanh Bao, Tripathi, Suryakant, Tripathy, Srikanth Prasad, Truelsen, Thomas Clement, Truong, Nu Thi, Tsadik, Afewerki Gebremeskel, Tsilimparis, Nikolaos, Tudor Car, Lorainne, Tuzcu, E Murat, Tyrovolas, Stefanos, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Usman, Muhammad Shariq, Uthman, Olalekan A, Uzun, Selen Begüm, Vaduganathan, Muthiah, Vaezi, Afsane, Vaidya, Gaurang, Valdez, Pascual R, Varavikova, Elena, Varughese, Santosh, Vasankari, Tommi Juhani, Vasconcelos, Ana Maria Nogales, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Villafaina, Santos, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Vosoughi, Kia, Vujcic, Isidora S, Wagner, Gregory R, Wagnew, Fasil Wagnew Shiferaw, Waheed, Yasir, Wang, Yanping, Wang, Yuan-Pang, Wassie, Molla Mesele, Weiderpass, Elisabete, Weintraub, Robert G, Weiss, Daniel J, Weiss, Jordan, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Widecka, Justyna, Widecka, Katarzyna, Wijeratne, Tissa, Winkler, Andrea Sylvia, Wiysonge, Charles Shey, Wolfe, Charles D A, Wondemagegn, Sintayehu Ambachew, Wu, Shouling, Wyper, Grant M A, Xu, Gelin, Yadav, Rajaram, Yakob, Bereket, Yamada, Tomohide, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Yasin, Yasin Jemal, Ye, Pengpeng, Yearwood, Jamal A, Yentür, Gökalp Kadri, Yeshaneh, Alex, Yimer, Ebrahim M, Yip, Paul, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, York, Hunter W, Yotebieng, Marcel, Younis, Mustafa Z, Yousefifard, Mahmoud, Yu, Chuanhua, Zachariah, Geevar, Zadnik, Vesna, Zafar, Shamsa, Zaidi, Zoubida, Zaman, Sojib Bin, Zamani, Mohammad, Zare, Zohreh, Zeeb, Hajo, Zeleke, Mulugeta Molla, Zenebe, Zerihun Menlkalew, Zerfu, Taddese Alemu, Zhang, Kai, Zhang, Xueying, Zhou, Maigeng, Zhu, Jun, Zodpey, Sanjay, Zucker, Inbar, Zuhlke, Liesl Joanna J, Lopez, Alan D, Gakidou, Emmanuela, and Murray, Christopher J L
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1. No poverty ,10. No inequality ,3. Good health
37. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016
- Author
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Nancy, Fullman, Jamal, Yearwood, Solomon, M, Abay, Cristiana, Abbafati, Foad, Abd-Allah, Jemal, Abdela, Ahmed, Abdelalim, Zegeye, Abebe, Teshome, Abuka, Abebo, Victor, Aboyans, Haftom, Niguse, Abraha, Daisy, M, X, Abreu, Laith, Abu-Raddad, J, Akilew, Awoke, Adane, Rufus, Adesoji, Adedoyin, Olatunji, Adetokunboh, Tara, Ballav, Adhikari, Mohsen, Afarideh, Ashkan, Afshin, Gina, Agarwal, Dominic, Agius, Anurag, Agrawal, Sutapa, Agrawal, Aliasghar, Ahmad, Kiadaliri, Miloud, Taki, Eddine, Aichour, Mohammed, Akibu, Rufus, Olusola, Akinyemi, Tomi, Akinyemiju, F, Nadia, Akseer, Faris, Hasan, Lami, Al, Fares, Alahdab, Ziyad, Al-Aly, Khurshid, Alam, Tahiya, Alam, Deena, Alasfoor, Mohammed, I, Albittar, Kefyalew, Addis, Alene, Ayman, Al-Eyadhy, Syed, Danish, Ali, Mehran, Alijanzadeh, Syed, M, Aljunid, Ala’A, Alkerwi, François, Alla, Peter, Allebeck, Christine, Allen, Mahmoud, A, Alomari, Rajaa, Al-Raddadi, Ubai, Alsharif, Khalid, A, Altirkawi, Nelson, Alvis-Guzman, Azmeraw, T, Amare, Kebede, Amenu, Walid, Ammar, Yaw, Ampem, Amoako, Nahla, Anber, Catalina, Liliana, Andrei, Sofia, Androudi, Carl, Abelardo, Antonio, T, Valdelaine, E, Araújo, M, Olatunde, Aremu, Johan, Ärnlöv, Artaman, Al, Krishna, Kumar, Aryal, Hamid, Asayesh, Ephrem, Tsegay, Asfaw, Solomon, Weldegebreal, Asgedom, Rana, Jawad, Asghar, Mengistu, Mitiku, Ashebir, Netsanet, Abera, Asseffa, Tesfay, Mehari, Atey, Sachin, R, Atre, Madhu, Atteraya, S, Leticia, Avila-Burgos, Euripide, Frinel, Arthur, G, Avokpaho, Ashish, Awasthi, Beatriz, Paulina, Ayala, Quintanilla, Animut, Alebel, Ayalew, Henok, Tadesse, Ayele, Rakesh, Ayer, Tambe, Betrand, Ayuk, Peter, Azzopardi, Natasha, Azzopardi-Muscat, Tesleem, Kayode, Babalola, Hamid, Badali, Alaa, Badawi, Maciej, Banach, Amitava, Banerjee, Amrit, Banstola, Ryan, M, Barber, Miguel, Barboza, A, Suzanne, L, Barker-Collo, Till, Bärnighausen, Simon, Barquera, Lope, H, Barrero, Quique, Bassat, Sanjay, Basu, Bernhard, T, Baune, Shahrzad, Bazargan-Hejazi, Neeraj, Bedi, Ettore, 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E, Dorsey, Kadine, Priscila, Bender, Dos, Santos, Kerrie, E, Doyle, Tim, Driscoll, R, Manisha, Dubey, Eleonora, Dubljanin, Bruce, Bartholow, Duncan, Michelle, Echko, Dumessa, Edessa, David, Edvardsson, Joshua, R, Ehrlich, Erika, Eldrenkamp, Ziad, El-Khatib, Matthias, Endres, Aman, Yesuf, Endries, Babak, Eshrati, Sharareh, Eskandarieh, Alireza, Esteghamati, Mahdi, Fakhar, Tamer, Farag, Mahbobeh, Faramarzi, Emerito, Jose, Aquino, Faraon, André, Faro, Farshad, Farzadfar, Adesegun, Fatusi, Mir, Sohail, Fazeli, Valery, Feigin, L, Andrea, B, Feigl, Netsanet, Fentahun, Seyed-Mohammad, Fereshtehnejad, Eduarda, Fernandes, João, C, Fernandes, Daniel, Obadare, Fijabi, Irina, Filip, Florian, Fischer, Christina, Fitzmaurice, Abraham, D, Flaxman, Luisa, Sorio, Flor, Nataliya, Foigt, Kyle, J, Foreman, Joseph, Frostad, J, Thomas, Fürst, Neal, D, Futran, Emmanuela, Gakidou, Silvano, Gallus, Ketevan, Gambashidze, Amiran, Gamkrelidze, Morsaleh, Ganji, Abadi, Kahsu, Gebre, Tsegaye, Tewelde, Gebrehiwot, 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Mohsen, Heidari, Delia, Hendrie, Nathaniel, J, Henry, Victor, Hugo, Herrera, Ballesteros, Claudiu, Herteliu, Desalegn, Tsegaw, Hibstu, Molla, Kahssay, Hiluf, Hans, W, Hoek, Enayatollah, Homaie, Rad, Nobuyuki, Horita, Dean, H, Hosgood, Mostafa, Hosseini, Seyed, Reza, Hosseini, Mihaela, Hostiuc, Sorin, Hostiuc, Damian, G, Hoy, Mohamed, Hsairi, Aung, Soe, Htet, Guoqing, Hu, John, J, Huang, Kim, Moesgaard, Iburg, Fachmi, Idris, Ehimario, Uche, Igumbor, Chad, Ikeda, Bogdan, Vasile, Ileanu, Olayinka, Ilesanmi, S, Kaire, Innos, Seyed, Sina, Naghibi, Irvani, Caleb, M, Irvine, S, Farhad, Islami, Troy, A, Jacobs, Kathryn, Jacobsen, H, Nader, Jahanmehr, Rajesh, Jain, Sudhir, Kumar, Jain, Mihajlo, Jakovljevic, M, Moti, Tolera, Jalu, Amr, Jamal, A, Mehdi, Javanbakht, Achala, Upendra, Jayatilleke, Panniyammakal, Jeemon, Ravi, Prakash, Jha, Vivekanand, Jha, Jacek, Józwiak, Oommen, John, Sarah, Charlotte, Johnson, Jost, Jonas, B, Vasna, Joshua, Mikk, Jürisson, Zubair, Kabir, Rajendra, Kadel, Amaha, 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Maria Jesu, Rivera, Juan A., Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Rostami, Ali, Roth, Gregory A., Rothenbacher, Dietrich, Roy, Ambuj, Roy, Nobhojit, Ruhago, George Mugambage, Sabde, Yogesh Damodar, Sachdev, Perminder S., Sadat, Nafi, Safdarian, Mahdi, Safiri, Saeid, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, Haniye Sadat, Salama, Joseph, Salamati, Payman, De Freitas Saldanha, Raphael, Salimzadeh, Hamideh, Salomon, Joshua A., Samy, Abdallah M., Sanabria, Juan Ramon, Sancheti, Parag K., Sanchez-Niño, Maria Dolore, Santomauro, Damian, Santos, Itamar S., Santric Milicevic, Milena M., Sarker, Abdur Razzaque, Sarrafzadegan, Nizal, Sartorius, Benn, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Saxena, Sonia, Saylan, Mete I., Schaeffner, Elke, Schmidhuber, Josef, Schmidt, Maria Inê, Schneider, Ione J.C., Schumacher, Austin E., Schutte, Aletta E., Schwebel, David C., Schwendicke, Falk, Sekerija, Mario, Sepanlou, Sadaf G., Servan-Mori, Edson E., Shafieesabet, Azadeh, Shaikh, Masood Ali, Shakh-Nazarova, Marina, Shams-Beyranvand, Mehran, Sharafi, Heidar, Sharif-Alhoseini, Mahdi, Shariful Islam, Sheikh Mohammed, Sharma, Meenakshi, Sharma, Rajesh, She, Jun, Sheikh, Aziz, Shfare, Mebrahtu Teweldemedhin, Shi, Peilin, Shields, Chloe, Shigematsu, Mika, Shinohara, Yukito, Shiri, Rahman, Shirkoohi, Reza, Shiue, Ivy, Shrime, Mark G., Shukla, Sharvari Rahul, Siabani, Soraya, Sigfusdottir, Inga Dora, Silberberg, Donald H., Silva, Diego Augusto Santo, Silva, João Pedro, Silveira, Dayane Gabriele Alve, Singh, Jasvinder A., Singh, Lavanya, Singh, Narinder Pal, Singh, Virendra, Sinha, Dhirendra Narain, Sinke, Abiy Hiruye, Sisay, Mekonnen, Skirbekk, Vegard, Sliwa, Karen, Smith, Alison, Soares Filho, Adauto Martin, Sobaih, Badr H.A., Somai, Melek, Soneji, Samir, Soofi, Moslem, Sorensen, Reed J.D., Soriano, Joan B., Soyiri, Ireneous N., Sposato, Luciano A., Sreeramareddy, Chandrashekhar T., Srinivasan, Vinay, Stanaway, Jeffrey D., Stathopoulou, Vasiliki, Steel, Nichola, Stein, Dan J., Stokes, Mark Andrew, Sturua, Lela, Sufiyan, Muawiyyah Babale, Suliankatchi, Rizwan Abdulkader, Sunguya, Bruno F., Sur, Patrick J., Sykes, Bryan L., Sylaja, P.N., Szoeke, Cassandra E.I., Tabarés-Seisdedos, Rafael, Tadakamadla, Santosh Kumar, Tadesse, Andualem Henok, Taffere, Getachew Redae, Tandon, Nikhil, Tariku, Amare Tariku, Taveira, Nuno, Tehrani-Banihashemi, Arash, Temam Shifa, Girma, Temsah, Mohamad-Hani, Terkawi, Abdullah Sulieman, Tesema, Azeb Gebresilassie, Tesfaye, Dawit Jember, Tessema, Belay, Thakur, J.S., Thomas, Nihal, Thompson, Matthew J., Tillmann, Taavi, To, Quyen G., Tobe-Gai, Ruoyan, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Foti, Torre, Anna, Tortajada, Miguel, Tran, Bach Xuan, Tran, Khanh Bao, Tripathi, Avnish, Tripathy, Srikanth Prasad, Troeger, Christopher, Truelsen, Thoma, Tsoi, Derrick, Tudor Car, Lorainne, Tuem, Kald Beshir, Tyrovolas, Stefano, Uchendu, Uche S., Ukwaja, Kingsley Nnanna, Ullah, Irfan, Updike, Rachel, Uthman, Olalekan A., Uzochukwu, Benjamin S. Chudi, Valdez, Pascual Rubén, Van Boven, Job F.M., Varughese, Santosh, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Violante, Francesco S., Vladimirov, Sergey K., Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Vos, Theo, Wagnew, Fasil, Waheed, Yasir, Wallin, Mitchell T., Walson, Judd L., Wang, Yafeng, Wang, Yuan-Pang, Wassie, Molla Mesele, Weaver, Marcia R., Weiderpass, Elisabete, Weintraub, Robert G., Weiss, Jordan, Weldegwergs, Kidu Gidey, Werdecker, Andrea, West, T. Eoin, Westerman, Ronny, White, Richard G., Whiteford, Harvey A., Widecka, Justyna, Winkler, Andrea Sylvia, Wiysonge, Charles Shey, Wolfe, Charles D.A., Wondimkun, Yohanes Ayele, Workicho, Abdulhalik, Wyper, Grant M.A., Xavier, Deni, Xu, Gelin, Yan, Lijing L., Yano, Yuichiro, Yaseri, Mehdi, Yimer, Nigus Bililign, Yin, Peng, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yonga, Gerald, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z., Yu, Chuanhua, Zadnik, Vesna, Zaidi, Zoubida, El Sayed Zaki, Maysaa, Zaman, Sojib Bin, Zamani, Mohammad, Zenebe, Zerihun Menlkalew, Zhou, Maigeng, Zhu, Jun, Zimsen, Stephanie R.M., Zipkin, Ben, Zodpey, Sanjay, Zuhlke, Liesl Joanna, Murray, Christopher J.L., Lozano, Rafael, Viðskiptadeild (HR), School of Business (RU), Háskólinn í Reykjavík, Reykjavik University, Abay, Sm, Abebo, Ta, Abraha, Hn, Abreu, Dmx, Abu-Raddad, Lj, Adane, Aa, Adedoyin, Ra, Adhikari, Tb, Aichour, Mte, Akinyemi, Ro, Akinyemiju, Tf, Al Lami, Fh, Albittar, Mi, Alene, Ka, Ali, Sd, Aljunid, Sm, Alomari, Ma, Altirkawi, Ka, Amare, At, Amoako, Ya, Andrei, Cl, Antonio, Cat, Araújo, Vem, Aryal, Kk, Asfaw, Et, Asgedom, Sw, Asghar, Rj, Ashebir, Mm, Asseffa, Na, Atey, Tm, Atre, Sr, Avokpaho, Efga, Ayala Quintanilla, Bp, Ayalew, Aa, Ayele, Ht, Ayuk, Tb, Babalola, Tk, Barber, Rm, Barboza, Ma, Barker-Collo, Sl, Barrero, Lh, Baune, Bt, Bekele, Bb, Belachew, Ab, Belay, Sa, Belay, Ya, Bell, Ml, Bello, Ak, Bennett, Da, Bennett, Jr, Bensenor, Im, Berhe, Df, Bhutta, Za, Bolliger, Iw, Bou-Orm, Ir, Brady, Oj, Breitborde, Njk, Butt, Za, Campos-Nonato, Ir, Campuzano, Jc, Carrero, Jj, Castañeda-Orjuela, Ca, Chang, Hy, Chang, Jc, Chiang, Pp, Chisumpa, Vh, Choi, Jj, Christopher, Dj, Chung, Sc, Ciobanu, Lg, Cortesi, Pa, Criqui, Mh, Cromwell, Ea, Crump, Ja, Daba, Ak, Dachew, Ba, Dadi, Af, Dargan, Pi, Das, Sk, De Neve, Jw, Dellavalle, Rp, Des Jarlais, Dc, Dharmaratne, Sd, Doku, Dt, Dorsey, Er, Dos Santos, Kpb, Doyle, Ke, Driscoll, Tr, Duncan, Bb, Ehrlich, Jr, El-Khatib, Zz, Endries, Ay, Faraon, Eja, Feigin, Vl, Feigl, Ab, Fereshtehnejad, Sm, Fernandes, Jc, Fijabi, Do, Flaxman, Ad, Foreman, Kj, Frostad, Jj, Futran, Nd, Gebre, Ak, Gebrehiwot, Tt, Gebremedhin, At, Gelaw, Ya, Geleijnse, Jm, Gething, Pw, Giref, Az, Gishu, Md, Godwin, Ww, Gona, Pn, Gopalani, Sv, Goulart, Ac, Gugnani, Hc, Haagsma, Ja, Hailu, Gb, Hamadeh, Rr, Hankey, Gj, Harb, Hl, Harewood, Hc, Haro, Jm, Hassen, Hy, Hay, Si, Hearps, Sjc, Hegazy, Mi, Henry, Nj, Herrera Ballesteros, Vh, Hibstu, Dt, Hiluf, Mk, Hoek, Hw, Hosgood, Hd, Hosseini, Sr, Hoy, Dg, Huang, Jj, Iburg, Km, Igumbor, Eu, Ileanu, Bv, Irvani, Ssn, Irvine, Cm, Jacobs, Ta, Jacobsen, Kh, Jain, Sk, Jakovljevic, Mb, Jalu, Mt, Jamal, Aa, Jayatilleke, Au, Jha, Rp, Johnson, Sc, Jonas, Jb, Karema, Ck, Karimi, Sm, Kassa, Dh, Kassa, Gm, Kassa, Td, Kassebaum, Nj, Katikireddi, Sv, Keiyoro, Pn, Kemp, Gr, Kengne, Ap, Ketema, Eb, Khafaie, Ma, Khalil, Ia, Khan, Ea, Khan, Mn, Khan, Ma, Khanal, Mn, Khang, Yh, Khater, Mm, Khoja, Ata, Kibret, Gd, Kiirithio, Dn, Kim, Yj, Kimokoti, Rw, Kopec, Ja, Koul, Pa, Krohn, Kj, Kumar, Ga, Kyu, Hh, Lad, Dp, Lal, Dk, Lang, Jj, Lansingh, Vc, Lazarus, Jv, Leasher, Jl, Lee, Ph, Leshargie, Ct, Liben, Ml, Lim, Ll, Lopez, Ad, Lorch, Sa, Lotufo, Pa, Lucas, Tcd, Lyons, Ra, Macarayan, Erk, Mackay, Mt, Maddison, Er, Malta, Dc, Mamun, Aa, Mansournia, Ma, Mantovani, Lg, Mapoma, Cc, Martins, Sco, Martins-Melo, Fr, Massenburg, Bb, Mathur, Mr, Maulik, Pk, Mcgrath, Jj, Mehta, Km, Meles, Kg, Memish, Za, Mengiste, Da, Mengistu, Dt, Menota, Bg, Mensah, Ga, Meretoja, Tj, Mezgebe, Hb, Miller, Tr, Mini, Gk, Mirrakhimov, Em, Mitchell, Pb, Mlashu, Fw, Mohammad, Ka, Mohammed, Ma, Mokdad, Ah, Mola, Gl, Montañez Hernandez, Jc, Morrison, Sd, Mousavi, Sm, Mueller, Uo, Murthy, Gv, Musa, Ki, Naik, Ga, Nansseu, Jrn, Narayan, Kv, Nascimento, Br, Negoi, Ri, Newton, Cr, Ngunjiri, Jw, Nguyen, Th, Ningrum, Dna, Nong, Vm, Norheim, Of, Noubiap, Jjn, Obermeyer, Cm, Ogbo, Fa, Oh, Ih, Olagunju, At, Olagunju, To, Olivares, Pr, Oliveira, Ppv, Olsen, He, Olusanya, Bo, Olusanya, Jo, Opio, Jn, Ortega-Altamirano, Dv, Pain, Aw, Palone, Mrt, Pandian, Jd, Park, Ek, Patil, St, Patton, Gc, Paturi, Vr, Pedroso, Mm, Pedroza, Sp, Pereira, Dm, Phillips, Mr, Piel, Fb, Pigott, Dm, Pillay, Jd, Piradov, Ma, Pond, Cd, Postma, Mj, Prasad, Nm, Quintana, Hk, Rahman, Ma, Rahman, Su, Rai, Rk, Raju, Sb, Rana, Sm, Rawaf, Dl, Ray, Se, Razo-García, Ca, Reiner, Rc, Reitsma, Mb, Renzaho, Amn, Ribeiro, Al, Rios Blancas, Mj, Rivera, Ja, Roth, Ga, Ruhago, Gm, Sabde, Yd, Sahraian, Ma, Saldanha, Rf, Salomon, Ja, Samy, Am, Sanabria, Jr, Sancheti, Pk, Sanchez-Niño, Md, Santric Milicevic, Mm, Sarker, Ar, Saylan, Mi, Schmidt, Mi, Schneider, Ijc, Schumacher, Ae, Schutte, Ae, Schwebel, Dc, Sepanlou, Sg, Servan-Mori, Ee, Shaikh, Ma, Shariful Islam, Sm, Shfare, Mt, Shrime, Mg, Shukla, Sr, Sigfusdottir, Id, Silberberg, Dh, Silva, Da, Silva, Jp, Silveira, Dga, Singh, Ja, Singh, Np, Sinha, Dn, Sinke, Ah, Soares Filho, Am, Sobaih, Bha, Sorensen, Rjd, Soriano, Jb, Soyiri, In, Sposato, La, Sreeramareddy, Ct, Stanaway, Jd, Stein, Dj, Stokes, Ma, Sufiyan, Mb, Suliankatchi, Ra, Sunguya, Bf, Sur, Pj, Sykes, Bl, Sylaja, Pn, Tadakamadla, Sk, Tadesse, Ah, Taffere, Gr, Tariku, At, Temsah, Mh, Tesema, Ag, Tesfaye, Dj, Thompson, Mj, To, Qg, Tran, Bx, Tran, Kb, Tripathy, Sp, Tuem, Kb, Ukwaja, Kn, Uthman, Oa, Uzochukwu, Bsc, Valdez, Pr, van Boven, Jfm, Vladimirov, Sk, Vlassov, Vv, Vollset, Se, Wallin, Mt, Walson, Jl, Wang, Yp, Wassie, Mm, Weaver, Mr, Weintraub, Rg, Weldegwergs, Kg, West, Te, White, Rg, Whiteford, Ha, Wolfe, Cd, Wondimkun, Ya, Wyper, Gma, Yan, Ll, Yimer, Nb, Yirsaw, Bd, Yoon, Sj, Younis, Mz, Zaki, Me, Zaman, Sb, Zenebe, Zm, Zimsen, Srm, Zuhlke, Lj, Murray, Cjl, and Lozano, R.
- Subjects
Peformance ,Coverage ,Dánartíðni ,Lífslíkur ,Life expectancy ,GBD ,Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016. Methods Drawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0–100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best) ,universal health coverage ,Article ,access quality health care ,health care access and quality index ,Nations ,Healthcare Acce ,Cause-specific mortality ,Psychology ,Healthcare Access and Quality Index ,Mælitæki ,States ,Medicine (all) ,Health care ,Þjóðir ,Public Health, Global Health, Social Medicine and Epidemiology ,Quality ,Heilbrigðisþjónusta ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Sálfræði ,Indicator ,Amenable mortality ,Transition ,we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0–100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derived from the broader GBD study and other data sources, we examined relationships between national HAQ Index scores and potential correlates of performance, such as total health spending per capita. Findings In 2016, HAQ Index performance spanned from a high of 97·1 (95% UI 95·8–98·1) in Iceland, followed by 96·6 (94·9–97·9) in Norway and 96·1 (94·5–97·3) in the Netherlands, to values as low as 18·6 (13·1–24·4) in the Central African Republic, 19·0 (14·3–23·7) in Somalia, and 23·4 (20·2–26·8) in Guinea-Bissau. The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. Striking subnational disparities emerged in personal health-care access and quality, with China and India having particularly large gaps between locations with the highest and lowest scores in 2016. In China, performance ranged from 91·5 (89·1–93·6) in Beijing to 48·0 (43·4–53·2) in Tibet (a 43·5-point difference), while India saw a 30·8-point disparity, from 64·8 (59·6–68·8) in Goa to 34·0 (30·3–38·1) in Assam. Japan recorded the smallest range in subnational HAQ performance in 2016 (a 4·8-point difference), whereas differences between subnational locations with the highest and lowest HAQ Index values were more than two times as high for the USA and three times as high for England. State-level gaps in the HAQ Index in Mexico somewhat narrowed from 1990 to 2016 (from a 20·9-point to 17·0-point difference), whereas in Brazil, disparities slightly increased across states during this time (a 17·2-point to 20·4-point difference). Performance on the HAQ Index showed strong linkages to overall development, with high and high-middle SDI countries generally having higher scores and faster gains for non-communicable diseases. Nonetheless, countries across the development spectrum saw substantial gains in some key health service areas from 2000 to 2016, most notably vaccine-preventable diseases. Overall, national performance on the HAQ Index was positively associated with higher levels of total health spending per capita, as well as health systems inputs, but these relationships were quite heterogeneous, particularly among low-to-middle SDI countries. Interpretation GBD 2016 provides a more detailed understanding of past success and current challenges in improving personal health-care access and quality worldwide. Despite substantial gains since 2000, many low-SDI and middle-SDI countries face considerable challenges unless heightened policy action and investments focus on advancing access to and quality of health care across key health services, especially non-communicable diseases. Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. Alongside initiatives to strengthen public health programmes, the pursuit of universal health coverage hinges upon improving both access and quality worldwide, and thus requires adopting a more comprehensive view—and subsequent provision—of quality health care for all populations ,Trends ,Inequalities - Abstract
Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016. Methods Drawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0-100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best); we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0-100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derived from the broader GBD study and other data sources, we examined relationships between national HAQ Index scores and potential correlates of performance, such as total health spending per capita. Findings In 2016, HAQ Index performance spanned from a high of 97.1 (95% UI 95.8-98.1) in Iceland, followed by 96.6 (94.9-97.9) in Norway and 96.1 (94.5-97.3) in the Netherlands, to values as low as 18.6 (13.1-24.4) in the Central African Republic, 19.0 (14.3-23.7) in Somalia, and 23.4 (20.2-26.8) in Guinea-Bissau. The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. Striking subnational disparities emerged in personal health-care access and quality, with China and India having particularly large gaps between locations with the highest and lowest scores in 2016. In China, performance ranged from 91.5 (89.1-936) in Beijing to 48.0 (43.4-53.2) in Tibet (a 43.5-point difference), while India saw a 30.8-point disparity, from 64.8 (59.6-68.8) in Goa to 34.0 (30.3-38.1) in Assam. Japan recorded the smallest range in subnational HAQ performance in 2016 (a 4.8-point difference), whereas differences between subnational locations with the highest and lowest HAQ Index values were more than two times as high for the USA and three times as high for England. State-level gaps in the HAQ Index in Mexico somewhat narrowed from 1990 to 2016 (from a 20.9-point to 17.0-point difference), whereas in Brazil, disparities slightly increased across states during this time (a 17.2-point to 20.4-point difference). Performance on the HAQ Index showed strong linkages to overall development, with high and high-middle SDI countries generally having higher scores and faster gains for non-communicable diseases. Nonetheless, countries across the development spectrum saw substantial gains in some key health service areas from 2000 to 2016, most notably vaccine-preventable diseases. Overall, national performance on the HAQ Index was positively associated with higher levels of total health spending per capita, as well as health systems inputs, but these relationships were quite heterogeneous, particularly among low-to-middle SDI countries. Interpretation GBD 2016 provides a more detailed understanding of past success and current challenges in improving personal health-care access and quality worldwide. Despite substantial gains since 2000, many low-SDI and middle-SDI countries face considerable challenges unless heightened policy action and investments focus on advancing access to and quality of health care across key health services, especially non-communicable diseases. Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. Alongside initiatives to strengthen public health programmes, the pursuit of universal health coverage upon improving both access and quality worldwide, and thus requires adopting a more comprehensive view and subsequent provision of quality health care for all populations., Bill & Melinda Gates Foundation. Barbora de Courten is supported by a National Heart Foundation Future Leader Fellowship (100864). Ai Koyanagi’s work is supported by the Miguel Servet contract financed by the CP13/00150 and PI15/00862 projects, integrated into the National R + D + I and funded by the ISCIII —General Branch Evaluation and Promotion of Health Research—and the European Regional Development Fund (ERDF-FEDER). Alberto Ortiz was supported by Spanish Government (Instituto de Salud Carlos III RETIC REDINREN RD16/0019 FEDER funds). Ashish Awasthi acknowledges funding support from Department of Science and Technology, Government of India through INSPIRE Faculty scheme Boris Bikbov has received funding from the European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement No. 703226. Boris Bikbov acknowledges that work related to this paper has been done on the behalf of the GBD Genitourinary Disease Expert Group. Panniyammakal Jeemon acknowledges support from the clinical and public health intermediate fellowship from the Wellcome Trust and Department of Biotechnology, India Alliance (2015–20). Job F M van Boven was supported by the Department of Clinical Pharmacy & Pharmacology of the University Medical Center Groningen, University of Groningen, Netherlands. Olanrewaju Oladimeji is an African Research Fellow hosted by Human Sciences Research Council (HSRC), South Africa and he also has honorary affiliations with Walter Sisulu University (WSU), Eastern Cape, South Africa and School of Public Health, University of Namibia (UNAM), Namibia. He is indeed grateful for support from HSRC, WSU and UNAM. EUI is supported in part by the South African National Research Foundation (NRF UID: 86003). Ulrich Mueller acknowledges funding by the German National Cohort Study grant No 01ER1511/D, Gabrielle B Britton is supported by Secretaría Nacional de Ciencia, Tecnología e Innovación and Sistema Nacional de Investigación de Panamá. Giuseppe Remuzzi acknowledges that the work related to this paper has been done on behalf of the GBD Genitourinary Disease Expert Group. Behzad Heibati would like to acknowledge Air pollution Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran. Syed Aljunid acknowledges the National University of Malaysia for providing the approval to participate in this GBD Project. Azeem Majeed and Imperial College London are grateful for support from the Northwest London National Insititute of Health Research (NIHR) Collaboration for Leadership in Applied Health Research & Care. Tambe Ayuk acknowledges the Institute of Medical Research and Medicinal Plant Studies for office space provided. José das Neves was supported in his contribution to this work by a Fellowship from Fundação para a Ciência e a Tecnologia, Portugal (SFRH/BPD/92934/2013). João Fernandes gratefully acknowledges funding from FCT–Fundação para a Ciência e a Tecnologia (grant number UID/Multi/50016/2013). Jan-Walter De Neve was supported by the Alexander von Humboldt Foundation. Kebede Deribe is funded by a Wellcome Trust Intermediate Fellowship in Public Health and Tropical Medicine (201900). Kazem Rahimi was supported by grants from the Oxford Martin School, the NIHR Oxford BRC and the RCUK Global Challenges Research Fund. Laith J Abu-Raddad acknowledges the support of Qatar National Research Fund (NPRP 9-040-3-008) who provided the main funding for generating the data provided to the GBD-IHME effort. Liesl Zuhlke is funded by the national research foundation of South Africa and the Medical Research Council of South Africa. Monica Cortinovis acknowledges that work related to this paper has been done on the behalf of the GBD Genitourinary Disease Expert Group. Chuanhua Yu acknowleges support from the National Natural Science Foundation of China (grant number 81773552 and grant number 81273179) Norberto Perico acknowledges that work related to this paper has been done on behalf of the GBD Genitourinary Disease Expert Group. Charles Shey Wiysonge’s work is supported by the South African Medical Research Council and the National Research Foundation of South Africa (grant numbers 106035 and 108571). John J McGrath is supported by grant APP1056929 from the John Cade Fellowship from the National Health and Medical Research Council and the Danish National Research Foundation (Niels Bohr Professorship). Quique Bassat is an ICREA (Catalan Institution for Research and Advanced Studies) research professor at ISGlobal. Richard G White is funded by the UK MRC and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement that is also part of the EDCTP2 programme supported by the European Union (MR/P002404/1), the Bill & Melinda Gates Foundation (TB Modelling and Analysis Consortium: OPP1084276/OPP1135288, CORTIS: OPP1137034/OPP1151915, Vaccines: OPP1160830), and UNITAID (4214-LSHTM-Sept15; PO 8477-0-600). Rafael Tabarés-Seisdedos was supported in part by grant number PROMETEOII/2015/021 from Generalitat Valenciana and the national grant PI17/00719 from ISCIII-FEDER. Mihajlo Jakovljevic acknowleges contribution from the Serbian Ministry of Education Science and Technological Development of the Republic of Serbia (grant OI 175 014). Shariful Islam is funded by a Senior Fellowship from Institute for Physical Activity and Nutrition, Deakin University and received career transition grants from High Blood Pressure Research Council of Australia. Sonia Saxena is funded by various grants from the NIHR. Stefanos Tyrovolas was supported by the Foundation for Education and European Culture, the Sara Borrell postdoctoral program (reference number CD15/00019 from the Instituto de Salud Carlos III (ISCIII–Spain) and the Fondos Europeo de Desarrollo Regional. Stefanos was awarded with a 6 months visiting fellowship funding at IHME from M-AES (reference no. MV16/00035 from the Instituto de Salud Carlos III). S Vittal Katikreddi was funded by a NHS Research Scotland Senior Clinical Fellowship (SCAF/15/02), the MRC (MC_UU_12017/13 & MC_ UU_12017/15) and the Scottish Government Chief Scientist Office (SPHSU13 & SPHSU15). Traolach S Brugha has received funding from NHS Digital UK to collect data used in this study. The work of Hamid Badali was financially supported by Mazandaran University of Medical Sciences, Sari, Iran. The work of Stefan Lorkowski is funded by the German Federal Ministry of Education and Research (nutriCARD, Grant agreement number 01EA1411A). Mariam Molokhia’s research was supported by the National Institute for Health Research (NIHR) Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. We also thank the countless individuals who have contributed to GBD 2016 in various capacities.
- Published
- 2018
38. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study.
- Author
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Fitzmaurice C, Abate D, Abbasi N, Abbastabar H, Abd-Allah F, Abdel-Rahman O, Abdelalim A, Abdoli A, Abdollahpour I, Abdulle ASM, Abebe ND, Abraha HN, Abu-Raddad LJ, Abualhasan A, Adedeji IA, Advani SM, Afarideh M, Afshari M, Aghaali M, Agius D, Agrawal S, Ahmadi A, Ahmadian E, Ahmadpour E, Ahmed MB, Akbari ME, Akinyemiju T, Al-Aly Z, AlAbdulKader AM, Alahdab F, Alam T, Alamene GM, Alemnew BTT, Alene KA, Alinia C, Alipour V, Aljunid SM, Bakeshei FA, Almadi MAH, Almasi-Hashiani A, Alsharif U, Alsowaidi S, Alvis-Guzman N, Amini E, Amini S, Amoako YA, Anbari Z, Anber NH, Andrei CL, Anjomshoa M, Ansari F, Ansariadi A, Appiah SCY, Arab-Zozani M, Arabloo J, Arefi Z, Aremu O, Areri HA, Artaman A, Asayesh H, Asfaw ET, Ashagre AF, Assadi R, Ataeinia B, Atalay HT, Ataro Z, Atique S, Ausloos M, Avila-Burgos L, Avokpaho EFGA, Awasthi A, Awoke N, Ayala Quintanilla BP, Ayanore MA, Ayele HT, Babaee E, Bacha U, Badawi A, Bagherzadeh M, Bagli E, Balakrishnan S, Balouchi A, Bärnighausen TW, Battista RJ, Behzadifar M, Behzadifar M, Bekele BB, Belay YB, Belayneh YM, Berfield KKS, Berhane A, Bernabe E, Beuran M, Bhakta N, Bhattacharyya K, Biadgo B, Bijani A, Bin Sayeed MS, Birungi C, Bisignano C, Bitew H, Bjørge T, Bleyer A, Bogale KA, Bojia HA, Borzì AM, Bosetti C, Bou-Orm IR, Brenner H, Brewer JD, Briko AN, Briko NI, Bustamante-Teixeira MT, Butt ZA, Carreras G, Carrero JJ, Carvalho F, Castro C, Castro F, Catalá-López F, Cerin E, Chaiah Y, Chanie WF, Chattu VK, Chaturvedi P, Chauhan NS, Chehrazi M, Chiang PP, Chichiabellu TY, Chido-Amajuoyi OG, Chimed-Ochir O, Choi JJ, Christopher DJ, Chu DT, Constantin MM, Costa VM, Crocetti E, Crowe CS, Curado MP, Dahlawi SMA, Damiani G, Darwish AH, Daryani A, das Neves J, Demeke FM, Demis AB, Demissie BW, Demoz GT, Denova-Gutiérrez E, Derakhshani A, Deribe KS, Desai R, Desalegn BB, Desta M, Dey S, Dharmaratne SD, Dhimal M, Diaz D, Dinberu MTT, Djalalinia S, Doku DT, Drake TM, Dubey M, Dubljanin E, Duken EE, Ebrahimi H, Effiong A, Eftekhari A, El Sayed I, Zaki MES, El-Jaafary SI, El-Khatib Z, Elemineh DA, Elkout H, Ellenbogen RG, Elsharkawy A, Emamian MH, Endalew DA, Endries AY, Eshrati B, Fadhil I, Fallah Omrani V, Faramarzi M, Farhangi MA, Farioli A, Farzadfar F, Fentahun N, Fernandes E, Feyissa GT, Filip I, Fischer F, Fisher JL, Force LM, Foroutan M, Freitas M, Fukumoto T, Futran ND, Gallus S, Gankpe FG, Gayesa RT, Gebrehiwot TT, Gebremeskel GG, Gedefaw GA, Gelaw BK, Geta B, Getachew S, Gezae KE, Ghafourifard M, Ghajar A, Ghashghaee A, Gholamian A, Gill PS, Ginindza TTG, Girmay A, Gizaw M, Gomez RS, Gopalani SV, Gorini G, Goulart BNG, Grada A, Ribeiro Guerra M, Guimaraes ALS, Gupta PC, Gupta R, Hadkhale K, Haj-Mirzaian A, Haj-Mirzaian A, Hamadeh RR, Hamidi S, Hanfore LK, Haro JM, Hasankhani M, Hasanzadeh A, Hassen HY, Hay RJ, Hay SI, Henok A, Henry NJ, Herteliu C, Hidru HD, Hoang CL, Hole MK, Hoogar P, Horita N, Hosgood HD, Hosseini M, Hosseinzadeh M, Hostiuc M, Hostiuc S, Househ M, Hussen MM, Ileanu B, Ilic MD, Innos K, Irvani SSN, Iseh KR, Islam SMS, Islami F, Jafari Balalami N, Jafarinia M, Jahangiry L, Jahani MA, Jahanmehr N, Jakovljevic M, James SL, Javanbakht M, Jayaraman S, Jee SH, Jenabi E, Jha RP, Jonas JB, Jonnagaddala J, Joo T, Jungari SB, Jürisson M, Kabir A, Kamangar F, Karch A, Karimi N, Karimian A, Kasaeian A, Kasahun GG, Kassa B, Kassa TD, Kassaw MW, Kaul A, Keiyoro PN, Kelbore AG, Kerbo AA, Khader YS, Khalilarjmandi M, Khan EA, Khan G, Khang YH, Khatab K, Khater A, Khayamzadeh M, Khazaee-Pool M, Khazaei S, Khoja AT, Khosravi MH, Khubchandani J, Kianipour N, Kim D, Kim YJ, Kisa A, Kisa S, Kissimova-Skarbek K, Komaki H, Koyanagi A, Krohn KJ, Bicer BK, Kugbey N, Kumar V, Kuupiel D, La Vecchia C, Lad DP, Lake EA, Lakew AM, Lal DK, Lami FH, Lan Q, Lasrado S, Lauriola P, Lazarus JV, Leigh J, Leshargie CT, Liao Y, Limenih MA, Listl S, Lopez AD, Lopukhov PD, Lunevicius R, Madadin M, Magdeldin S, El Razek HMA, Majeed A, Maleki A, Malekzadeh R, Manafi A, Manafi N, Manamo WA, Mansourian M, Mansournia MA, Mantovani LG, Maroufizadeh S, Martini SMS, Mashamba-Thompson TP, Massenburg BB, Maswabi MT, Mathur MR, McAlinden C, McKee M, Meheretu HAA, Mehrotra R, Mehta V, Meier T, Melaku YA, Meles GG, Meles HG, Melese A, Melku M, Memiah PTN, Mendoza W, Menezes RG, Merat S, Meretoja TJ, Mestrovic T, Miazgowski B, Miazgowski T, Mihretie KMM, Miller TR, Mills EJ, Mir SM, Mirzaei H, Mirzaei HR, Mishra R, Moazen B, Mohammad DK, Mohammad KA, Mohammad Y, Darwesh AM, Mohammadbeigi A, Mohammadi H, Mohammadi M, Mohammadian M, Mohammadian-Hafshejani A, Mohammadoo-Khorasani M, Mohammadpourhodki R, Mohammed AS, Mohammed JA, Mohammed S, Mohebi F, Mokdad AH, Monasta L, Moodley Y, Moosazadeh M, Moossavi M, Moradi G, Moradi-Joo M, Moradi-Lakeh M, Moradpour F, Morawska L, Morgado-da-Costa J, Morisaki N, Morrison SD, Mosapour A, Mousavi SM, Muche AA, Muhammed OSS, Musa J, Nabhan AF, Naderi M, Nagarajan AJ, Nagel G, Nahvijou A, Naik G, Najafi F, Naldi L, Nam HS, Nasiri N, Nazari J, Negoi I, Neupane S, Newcomb PA, Nggada HA, Ngunjiri JW, Nguyen CT, Nikniaz L, Ningrum DNA, Nirayo YL, Nixon MR, Nnaji CA, Nojomi M, Nosratnejad S, Shiadeh MN, Obsa MS, Ofori-Asenso R, Ogbo FA, Oh IH, Olagunju AT, Olagunju TO, Oluwasanu MM, Omonisi AE, Onwujekwe OE, Oommen AM, Oren E, Ortega-Altamirano DDV, Ota E, Otstavnov SS, Owolabi MO, P A M, Padubidri JR, Pakhale S, Pakpour AH, Pana A, Park EK, Parsian H, Pashaei T, Patel S, Patil ST, Pennini A, Pereira DM, Piccinelli C, Pillay JD, Pirestani M, Pishgar F, Postma MJ, Pourjafar H, Pourmalek F, Pourshams A, Prakash S, Prasad N, Qorbani M, Rabiee M, Rabiee N, Radfar A, Rafiei A, Rahim F, Rahimi M, Rahman MA, Rajati F, Rana SM, Raoofi S, Rath GK, Rawaf DL, Rawaf S, Reiner RC, Renzaho AMN, Rezaei N, Rezapour A, Ribeiro AI, Ribeiro D, Ronfani L, Roro EM, Roshandel G, Rostami A, Saad RS, Sabbagh P, Sabour S, Saddik B, Safiri S, Sahebkar A, Salahshoor MR, Salehi F, Salem H, Salem MR, Salimzadeh H, Salomon JA, Samy AM, Sanabria J, Santric Milicevic MM, Sartorius B, Sarveazad A, Sathian B, Satpathy M, Savic M, Sawhney M, Sayyah M, Schneider IJC, Schöttker B, Sekerija M, Sepanlou SG, Sepehrimanesh M, Seyedmousavi S, Shaahmadi F, Shabaninejad H, Shahbaz M, Shaikh MA, Shamshirian A, Shamsizadeh M, Sharafi H, Sharafi Z, Sharif M, Sharifi A, Sharifi H, Sharma R, Sheikh A, Shirkoohi R, Shukla SR, Si S, Siabani S, Silva DAS, Silveira DGA, Singh A, Singh JA, Sisay S, Sitas F, Sobngwi E, Soofi M, Soriano JB, Stathopoulou V, Sufiyan MB, Tabarés-Seisdedos R, Tabuchi T, Takahashi K, Tamtaji OR, Tarawneh MR, Tassew SG, Taymoori P, Tehrani-Banihashemi A, Temsah MH, Temsah O, Tesfay BE, Tesfay FH, Teshale MY, Tessema GA, Thapa S, Tlaye KG, Topor-Madry R, Tovani-Palone MR, Traini E, Tran BX, Tran KB, Tsadik AG, Ullah I, Uthman OA, Vacante M, Vaezi M, Varona Pérez P, Veisani Y, Vidale S, Violante FS, Vlassov V, Vollset SE, Vos T, Vosoughi K, Vu GT, Vujcic IS, Wabinga H, Wachamo TM, Wagnew FS, Waheed Y, Weldegebreal F, Weldesamuel GT, Wijeratne T, Wondafrash DZ, Wonde TE, Wondmieneh AB, Workie HM, Yadav R, Yadegar A, Yadollahpour A, Yaseri M, Yazdi-Feyzabadi V, Yeshaneh A, Yimam MA, Yimer EM, Yisma E, Yonemoto N, Younis MZ, Yousefi B, Yousefifard M, Yu C, Zabeh E, Zadnik V, Moghadam TZ, Zaidi Z, Zamani M, Zandian H, Zangeneh A, Zaki L, Zendehdel K, Zenebe ZM, Zewale TA, Ziapour A, Zodpey S, and Murray CJL
- Subjects
- Disabled Persons, Global Burden of Disease, Global Health, Humans, Incidence, Quality-Adjusted Life Years, Neoplasms epidemiology
- Abstract
Importance: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data., Objective: To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning., Evidence Review: We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence., Findings: In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572 000 deaths and 15.2 million DALYs), and stomach cancer (542 000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819 000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601 000 deaths and 17.4 million DALYs), TBL cancer (596 000 deaths and 12.6 million DALYs), and colorectal cancer (414 000 deaths and 8.3 million DALYs)., Conclusions and Relevance: The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer care.
- Published
- 2019
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