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In tihs tstudy, it was aimed to compare four different cgogulase test results which were used to detect coagulase activity in staphylococci. The coagulase activity of 200 strains of staphylococci isolated from various clinical samples were investigated using slide coagulase tests with human and rabbit plasma, tube coagulase test with human plasma and commercial latex agglutination kit wich contains lgG and fibrinogen bound to the latex particles. Among the tests a correlation was found in 181 strains, but not in 19 strains. The tube coagulase test as reference teset is still reliable. However it seems that other tests are also valuable as alternative tests.

The incidence of slime production was investigated in coagulase-negative staphylococci (CNS) strains isolated from different clinical samples using Congo red agar method. A total of 131 CNS strains, which consist of 105 (80%) wound swabs, 21 (16%) blood samples from patients with intravenous catheter and 5 (4%) urine specimens were studied. The production of slime factor was detected in 45 (43%) CNS strains isolated from the wound swabs, in 12 (57%) strains isolated from blood samples and in all urine specimens. The rate of slime production was 47%. Slime factor positive CNS strains were reported more virulent and resistent to antimicrobial agents. The treatment of infections caused by this strains does not produce a satisfactory results in clinics. In our study, slime production in CNS strains as a causative agent isolated from different clinical samples were found at a high rate. We concluded that wheither the strains produce slime factor, or not, should be reported to clinicians to obtain.