1. Bloodstream Infections in Severe Burn Patients: Epidemiology, Microbiology, Laboratory Features, and Risk Factors Associated with Mortality
- Author
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Burcu ÖZDEMİR, Esragül AKINCI, Ayşe BUT, Sümeyye KAZANCIOĞLU, Ahmet Çınar YASTI, Yunus Nadi YÜKSEK, İsa SÖZEN, and Hürrem BODUR
- Subjects
bloodstream infections ,burn patients ,risk factor ,mortality ,Medicine ,Infectious and parasitic diseases ,RC109-216 - Abstract
Introduction: Bloodstream infections (BSI) are a major cause of morbidity and mortality in burn patients. Early empiric antibiotic treatment directed against pathogens is critical. Studies on BSI are limited in burn patients. This study aimed to investigate the epidemiological, clinical, and laboratory features of cases with BSI detected in the burn unit and the factors affecting mortality. Materials and Methods: Herein, we retrospectively studied sixty-eight inpatients diagnosed with BSI in the burn unit of our hospital during 2014-2018. Results: Among the sixty-eight cases included in the study, 73.5% were male, and the median age was 38. We observed that 25% of the cases had two-degree burns and 75% had third-degree burns, and the median total burn surface area (TBSA) was 36%. Eighty-six bacteremia episodes were detected in sixty-eight cases. The most common isolated bacteria were (75.5%) Gram-negative bacilli (Pseudomonas spp. and Acinetobacter spp.). Carbapenem resistance was detected in 63% of Gram-negative bacteria. The overall mortality was 35.3% (24/68). In the deceased cases, the median time between bacteremia and mortality was 3.5 days. In addition, the mortality was statistically significantly higher in cases with a TBSA of >40% and thrombocytopenia (p
- Published
- 2022
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