11 results on '"Axumawi Gebreyohanes"'
Search Results
2. Prognostic Factors for Surgically Managed Spontaneous Spinal Epidural Hematoma: A Single-Center Case Series of 18 Patients
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Asfand Baig Mirza, Jose Pedro Lavrador, Axumawi Gebreyohanes, Amisha Vastani, Musa China, Dimitrios Kalaitzoglou, James Bartram, Hazem Eid, Christina Bleil, David Bell, Nicholas Thomas, Irfan Malik, and Gordan Grahovac
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Surgery ,Neurology (clinical) - Published
- 2022
3. Dorsal root entry zone lesioning for brachial plexus avulsion pain: a case series
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Axumawi Gebreyohanes, Aminul Islam Ahmed, and David Choi
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Neurology ,Dermatology - Published
- 2023
4. Systematic Review of Surgical Management of Spinal Intradural Arachnoid Cysts
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Axumawi Gebreyohanes, Qusai Al Banna, Amisha Vastani, Asfand Baig Mirza, Ahilan Kailaya Vasan, James Bartram, José Pedro Lavrador, and Gordan Grahovac
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,MEDLINE ,Spinal Cord Diseases ,medicine ,Humans ,Spinal canal ,Cyst ,Pathological ,business.industry ,Marsupialization ,Spinal cord ,medicine.disease ,Magnetic Resonance Imaging ,Spine ,Syringomyelia ,Surgery ,Arachnoid Cysts ,medicine.anatomical_structure ,Systematic review ,Etiology ,Female ,Neurology (clinical) ,business - Abstract
Objective Spinal intradural arachnoid cysts (SIACs) are rare pathological lesions that can arise via outpouchings of the arachnoid layer in the spinal canal that can result in neurological deficits. We performed a systematic literature review regarding the current surgical techniques used in the management of SIACs and discussed the prevailing hypotheses surrounding the etiology of SIACs. Methods A systematic search of the literature was performed in December 2020 using EMBASE and MEDLINE for reports regarding the surgical management of SIACs. Data were collected regarding the demographics of the patients, classification system used, presence or absence of syrinxes, preoperative imaging modality, surgical approach and extent of resection, and postoperative outcomes and follow-up. Results Our search yielded 19 reports for inclusion in the present study. The 19 studies included a total of 414 cases, with an overall male/female ratio of 0.93:1. The most common site for the SIACs was the thoracic spinal cord at 77.5%. The symptoms were very similar across the 19 studies. Of the 19 studies, 15 had used resection to manage the SIACs, 10 had used fenestration or marsupialization, and 4 had used cystoarachnoid or cystoperitoneal shunts. Conclusions SIACs are rare and debilitating spinal pathological lesions, with the etiology of primary SIACs still not fully elucidated. Multiple surgical approaches have been effective, with the optimal operative strategy largely dependent on the individual patient and cyst factors on a case-by-case basis.
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- 2022
5. Intraoperative Neurophysiological Monitoring for Intradural Extramedullary Spinal Tumours
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Asfand Baig Mirza, Amisha Vastani, Christoforos Syrris, Timothy Boardman, Imran Ghani, Christopher Murphy, Axumawi Gebreyohanes, Francesco Vergani, Ana Mirallave-Pescador, Jose P. Lavrador, Ahilan Kailaya Vasan, and Gordan Grahovac
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Orthopedics and Sports Medicine ,Surgery ,Neurology (clinical) - Abstract
Study Design Retrospective cohort study. Objectives Intraoperative neurophysiological monitoring (IONM) is widely used in spinal neurosurgery, particularly for intramedullary tumours. However, its validity in intradural extramedullary (IDEM) spinal tumours is less clearly defined, this being the focus of this study. Methods We compared outcomes for patients that underwent resection of IDEM tumours with and without IONM between 2010 and 2020. Primary outcomes were postoperative American Spinal Injury Association (ASIA) scores. Other factors assessed were use of intraoperative ultrasound, drain placement, postoperative complications, postoperative Eastern Cooperative Oncology Group (ECOG) score, extent of resection, length of hospital stay, discharge location and recurrence. Results 163 patients were included, 71 patients in the IONM group and 92 in the non-IONM group. No significant differences were noted in baseline demographics. For preoperative ASIA D patients, 44.0% remained ASIA D and 49.9% improved to ASIA E in the IONM group, compared to 39.7% and 30.2% respectively in the non-IONM group. For preoperative ASIA E patients, 50.3% remained ASIA E and 44.0% deteriorated to ASIA D in the IONM group, compared to 30.2% and 39.7% respectively in the non-IONM group (all other patients deteriorated further). Length of inpatient stay was significantly shorter in the IONM group ( P = .043). There were no significant differences in extent of resection, postoperative complications, discharge location or tumour recurrence. Conclusions Research focusing on the use of IONM in IDEM tumour surgery remains scarce. Our study supports the use of IONM during surgical excision of IDEM tumours.
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- 2022
6. Appraising The Evidence for Conservative versus Surgical Management of Motor Deficits in Degenerative Cervical Radiculopathy
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Axumawi Gebreyohanes, Marios Erotocritou, and David Choi
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Orthopedics and Sports Medicine ,Surgery ,Neurology (clinical) - Abstract
Study Design Systematic review. Objectives Understanding the prevalence and outcome of motor deficits in degenerative cervical radiculopathy is important to guide management. We compared motor radiculopathy outcomes after conservative and surgical management, a particular focus being painful vs painless radiculopathy. Methods MEDLINE and EMBASE databases were searched. We stratified each study cohort into 1 of 6 groups, I–VI, based on whether radiculopathy was painful, painless or unspecified, and whether interventions were surgical or non-surgical. Results Of 10 514 initial studies, 44 matched the selection criteria. Whilst 42 (95.5%) provided baseline motor radiculopathy data, only 22 (50.0%) provided follow-up motor outcomes. Mean baseline prevalence of motor deficits was 39.1% (9.2%–73.3%) in conservative cohorts and 60.5% (18.5%–94.1%) in surgical cohorts. Group VI, ‘surgically-managed motor radiculopathy with unclear pain status’ had the largest number of cohorts. Conversely, no cohorts were found in Group III, ‘conservatively-managed painless motor radiculopathy’. Large disparities in data quality made direct comparison of conservative vs operative management difficult. Conclusions Overall pre-intervention prevalence of motor deficits in degenerative cervical radiculopathy is 56.4%. Many studies fail to report motor outcomes after intervention, meaning statistical evidence to guide optimal management of motor radiculopathy is currently lacking. Our study highlights the need for more evidence, preferably from a prospective long-term study, to allow direct comparisons of motor outcomes after conservative and surgical management.
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- 2022
7. Prognostic factors for surgically managed intramedullary spinal cord tumours: a single-centre case series
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Asfand Baig Mirza, Axumawi Gebreyohanes, James Knight, James Bartram, Amisha Vastani, Dimitrios Kalaitzoglou, Jose Pedro Lavrador, Ahilan Kailaya-Vasan, Eleni Maratos, David Bell, Nick Thomas, Richard Gullan, Irfan Malik, and Gordan Grahovac
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Adult ,Aged, 80 and over ,Pain ,Astrocytoma ,Middle Aged ,Prognosis ,Hemangioblastoma ,Young Adult ,Treatment Outcome ,Ependymoma ,Humans ,Surgery ,Neurology (clinical) ,Spinal Cord Neoplasms ,Aged ,Retrospective Studies - Abstract
Intramedullary spinal cord tumours (IMSCTs) are comparatively rare neoplasms. We present a single-centre clinical case series of adult patients with surgically managed IMSCTs.We performed a retrospective analysis of electronic patient records in the time period spanning July 2010 to July 2021. All adult patients that had undergone surgical management for IMSCTs were eligible for inclusion. Baseline and post-operative clinical and radiological characteristics, along with follow-up data, were assessed. We also performed a literature review with a focus on surgical outcomes for IMSCTs.Sixty-six patients matched our selection criteria, with a median age of 42 years (range 23-85). Thirty-four ependymomas, 17 haemangioblastomas, 12 astrocytomas, 2 lymphomas and 1 teratoma were included. Statistical analysis yielded several significant findings: IMSCTs spanning a greater number of vertebral levels are significantly associated with poor McCormick outcomes (p = 0.03), presence of gait disturbance before surgery is significantly associated with poor outcome for both post-operative McCormick and Nurick scores (p = 0.007), and radicular pain present pre-operatively is significantly associated with a good post-operative McCormick score (p = 0.045). Haemangioblastomas are significantly more likely to have a clear intra-operative dissection plane compared to ependymomas and astrocytomas (p = 0.009). However, astrocytomas have a significantly higher prevalence of good McCormick outcomes compared to ependymomas and haemangioblastomas (p = 0.03).Histological diagnosis, cranio-caudal extent of the tumour and the presence or absence of baseline deficits-such as gait impairment and radicular pain-are significant in determining neurological outcomes after surgery for IMSCTs.
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- 2022
8. Surgical management and outcomes in spinal intradural arachnoid cysts: the experience from two tertiary neurosurgical centres
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Asfand Baig Mirza, David Choi, James Bartram, Axumawi Gebreyohanes, José Pedro Lavrador, Timothy Boardman, Gordan Grahovac, Edward W Dyson, Amisha Vastani, Vittorio M. Russo, Siddharth Sinha, and Ahilan Kailaya Vasan
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Male ,medicine.medical_specialty ,business.industry ,Spinal intradural arachnoid cysts ,Urinary system ,Gold standard ,Pain ,medicine.disease ,Urinary function ,Spinal Cord Diseases ,Syringomyelia ,Surgery ,Arachnoid Cysts ,Treatment Outcome ,medicine ,Humans ,Cyst ,Observational study ,Syrinx (medicine) ,Female ,Neurology (clinical) ,Paresthesia ,Presentation (obstetrics) ,business - Abstract
PURPOSE Evaluation of the presentation and outcomes of different surgical treatment approaches for spinal intradural arachnoid cysts (SIAC). METHODS Cases were identified from electronic records of two major neurosurgical centres in London over the last 10 years (October 2009-October 2019) that have been surgically treated in both institutions. Clinical findings, surgical technique, and recurrence by procedure were statistically analysed. Statistical analysis was performed with STATA 13.1 Software. RESULTS A total of 42 patients with SIAC were identified for this study with a mean age at the time of surgery of 53.6 years and a male:female ratio of 8:13. There were 31 patients with primary SIACs and 11 with secondary SIACs. The most common presenting symptom was paraesthesia (n = 27). The most common location of the cyst was in the thoracic region (n = 33). Syrinx was present in 26.2% of SIACs (n = 11). Resection was associated with significantly better postoperative pain compared to other surgical techniques (p = 0.01), significantly poorer postoperative urinary function (p = 0.029), and lower rates of sensory recovery in patients who presented preoperatively with sensory deficit (p = 0.041). No significant difference was seen in symptomatic outcomes between patients with primary and secondary SIACs. CONCLUSION Resection and drainage are both effective methods of managing SIACs. In this observational study, resection was associated with significantly reduced pain postoperatively when compared with drainage, however also with significantly less improvement in postoperative urinary function. Therefore, resection should be the gold standard management option for SIACs, with drainage as an option where resection is unsafe, and drainage should also be considered in patients presenting with urinary dysfunction.
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- 2021
9. Iatrogenic dorsal spinal cord herniation and repair with clip-based expansile duraplasty: a case report
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Axumawi Gebreyohanes, Arshad Zubair, Jonathan Lui, Adrian Casey, and Parag Sayal
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Titanium ,Hernia ,Neurology ,Spinal Cord ,Iatrogenic Disease ,Humans ,Case Report ,Dermatology ,Child ,Surgical Instruments ,Herniorrhaphy ,Thoracic Vertebrae - Abstract
INTRODUCTION: Myelopathy arising due to dorsal herniation of the spinal cord is a rare phenomenon, particularly so in the thoracic region. Where cases of thoracic dorsal cord herniation have been reported, the aetiology has typically been non-iatrogenic. CASE PRESENTATION: We report the case of a paediatric oncology patient who presented with neurological deterioration secondary to thoracic dorsal spinal cord herniation, manifesting three months after laminectomy for biopsy of a spinal medulloblastoma lesion. We repaired the dural defect using non-penetrating titanium clips to create a secure expansile duraplasty, resulting in radiologically evident reduction of the cord herniation as well as corresponding clinical improvement. DISCUSSION: Thoracic dorsal spinal cord herniation is an extremely rare occurrence after spinal surgery. Non-penetrating titanium clips can be used to form a secure expansile duraplasty following reduction of the cord herniation. Successful repair of the dural defect re-anteriorises the cord and can confer neurological benefit.
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- 2021
10. Spinal intradural arachnoid cysts - A multicentre case series assessing management and outcomes
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Axumawi Gebreyohanes, Vittorio M Russo, Edward W Dyson, Timothy Boardman, Siddharth Sinha, Amisha Vastani, James Bartram, Asfand Baig Mirza, David Choi, Gordan Grahovac, and Ahilan Kailaya-Vasan
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medicine.medical_specialty ,business.industry ,Spinal intradural arachnoid cysts ,medicine ,Radiology ,Neurology. Diseases of the nervous system ,business ,RC346-429 - Published
- 2021
11. Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion: A Comprehensive Literature Review
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David Choi, Axumawi Gebreyohanes, and Aminul Islam Ahmed
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Dorsum ,medicine.medical_specialty ,Neurosurgical Procedures ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,Brachial Plexus ,business.industry ,Avulsion fracture ,medicine.disease ,Spinal cord ,Brachial plexus avulsion ,Neurosurgical Procedure ,Surgery ,Nociception ,medicine.anatomical_structure ,Spinal Cord ,030220 oncology & carcinogenesis ,Neuropathic pain ,Neuralgia ,Neurology (clinical) ,business ,Spinal Nerve Roots ,Brachial plexus ,030217 neurology & neurosurgery - Abstract
Dorsal root entry zone (DREZ) lesioning is a neurosurgical procedure that aims to relieve severe neuropathic pain in patients with brachial plexus avulsion by selectively destroying nociceptive neural structures in the posterior cervical spinal cord. Since the introduction of the procedure over 4 decades ago, the DREZ lesioning technique has undergone numerous modifications, with a variety of center- and surgeon-dependent technical differences and patient outcomes. We have reviewed the literature to discuss reported methods of DREZ lesioning and outcomes.
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- 2020
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