Search

Your search keyword '"Awadie, Halim"' showing total 177 results
Start Over Author "Awadie, Halim"
177 results on '"Awadie, Halim"'

3. A subepithelial lesion algorithm for endoscopic (SAFE) resection in the upper gastrointestinal tract.

Author

Gupta, Sunil, Gauci, Julia, O'Sullivan, Timothy, Cronin, Oliver, Whitfield, Anthony, Craciun, Ana, Awadie, Halim, Yang, Jing, Kwan, Vu, Lee, Eric Y. T., Burgess, Nicholas G., and Bourke, Michael J.

Subjects
ENDOSCOPIC ultrasonography, ENDOSCOPIC surgery, COMPUTED tomography, SURGERY, LAPAROSCOPIC surgery
Abstract

Background Complete excision of upper gastrointestinal subepithelial lesions (U-SELs) eliminates diagnostic uncertainty, obviates the need for surveillance, and may be necessary for definitive diagnosis and management. Current guidelines lack precision and cohesion, and surgery is associated with significant morbidity. We describe and report on the outcomes of our SEL algorithm for endoscopic (SAFE) resection. Methods U-SELs were enrolled prospectively over 115 months until March 2023. All subjects underwent axial (computed tomography) imaging and endoscopic ultrasonography (EUS) to exclude a large exophytic component or invasion into local structures, and assess for muscularis propria (MP) involvement. Results 106 U-SELs (41 esophageal, 65 gastric) were resected (mean patient age 60.6 [SD 13.4]; 51.9% male). Esophageal U-SELs underwent endoscopic submucosal dissection (ESD; n = 22) or submucosal tunneling endoscopic resection (STER) if MP involvement was suspected (n = 19). Gastric U-SELs underwent STER (n = 6 at cardia), ESD (n = 47), or exposing endoscopic full-thickness resection (e-EFTR; n = 12). Technical success rates were 97.6% and 92.3%, respectively. Among the noncardiac gastric U-SELs, five resections (9.6%) were completed laparoscopically owing to deep and broad full-thickness involvement; five (9.6%) required laparoscopic gastrotomy and surgical retrieval after successful resection and closure owing to a large lesion size (mean 47 mm). There was no delayed bleeding, perforation, or recurrence at 13 months. Conclusion U-SELs may be effectively and safely treated by endoscopic resection. The SAFE approach provides a framework that facilitates structured decision-making. Esophageal U-SELs suspected of involving the MP should undergo STER. Gastric SELs are best managed by ESD, with a view to proceeding to e-EFTR. A laparoscopic upper gastrointestinal surgeon should be available in case surgical retrieval of the specimen or laparoscopic completion is required. [ABSTRACT FROM AUTHOR]

Published
2025
Full Text
View/download PDF

14. Endoscopic diagnosis and management of esophagogastric variceal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Author

Gralnek, Ian M., additional, Camus Duboc, Marine, additional, Garcia-Pagan, Juan Carlos, additional, Fuccio, Lorenzo, additional, Karstensen, John Gásdal, additional, Hucl, Tomas, additional, Jovanovic, Ivan, additional, Awadie, Halim, additional, Hernandez-Gea, Virginia, additional, Tantau, Marcel, additional, Ebigbo, Alanna, additional, Ibrahim, Mostafa, additional, Vlachogiannakos, Jiannis, additional, Burgmans, Marc C., additional, Rosasco, Robyn, additional, and Triantafyllou, Konstantinos, additional

Published
2022
Full Text
View/download PDF

15. Endoscopic diagnosis and management of esophagogastric variceal hemorrhage:European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Author

Gralnek, Ian M., Camus Duboc, Marine, Garcia-Pagan, Juan Carlos, Fuccio, Lorenzo, Karstensen, John Gásdal, Hucl, Tomas, Jovanovic, Ivan, Awadie, Halim, Hernandez-Gea, Virginia, Tantau, Marcel, Ebigbo, Alanna, Ibrahim, Mostafa, Vlachogiannakos, Jiannis, Burgmans, Marc C., Rosasco, Robyn, Triantafyllou, Konstantinos, Gralnek, Ian M., Camus Duboc, Marine, Garcia-Pagan, Juan Carlos, Fuccio, Lorenzo, Karstensen, John Gásdal, Hucl, Tomas, Jovanovic, Ivan, Awadie, Halim, Hernandez-Gea, Virginia, Tantau, Marcel, Ebigbo, Alanna, Ibrahim, Mostafa, Vlachogiannakos, Jiannis, Burgmans, Marc C., Rosasco, Robyn, and Triantafyllou, Konstantinos

Abstract

1: ESGE recommends that patients with compensated advanced chronic liver disease (ACLD; due to viruses, alcohol, and/or nonobese [BMI < 30 kg/m2] nonalcoholic steatohepatitis) and clinically significant portal hypertension (hepatic venous pressure gradient [HVPG] > 10 mmHg and/or liver stiffness by transient elastography > 25 kPa) should receive, if no contraindications, nonselective beta blocker (NSBB) therapy (preferably carvedilol) to prevent the development of variceal bleeding.Strong recommendation, moderate quality evidence. 2: ESGE recommends that in those patients unable to receive NSBB therapy with a screening upper gastrointestinal (GI) endoscopy that demonstrates high risk esophageal varices, endoscopic band ligation (EBL) is the endoscopic prophylactic treatment of choice. EBL should be repeated every 2-4 weeks until variceal eradication is achieved. Thereafter, surveillance EGD should be performed every 3-6 months in the first year following eradication.Strong recommendation, moderate quality evidence. 3: ESGE recommends, in hemodynamically stable patients with acute upper GI hemorrhage (UGIH) and no history of cardiovascular disease, a restrictive red blood cell (RBC) transfusion strategy, with a hemoglobin threshold of ≤ 70 g/L prompting RBC transfusion. A post-transfusion target hemoglobin of 70-90 g/L is desired.Strong recommendation, moderate quality evidence. 4 : ESGE recommends that patients with ACLD presenting with suspected acute variceal bleeding be risk stratified according to the Child-Pugh score and MELD score, and by documentation of active/inactive bleeding at the time of upper GI endoscopy.Strong recommendation, high quality of evidence. 5 : ESGE recommends the vasoactive agents terlipressin, octreotide, or somatostatin be initiated at the time of presentation in patients with suspected acute variceal bleeding and be continued for a duration of up to 5 days.Strong recommendation, high quality evidence. 6 : ESGE recommends an

Published
2022

19. Erratum: Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline (Journal of Physical Chemistry (2021) 53 DOI: 10.1055/a-1496-8969)

Author

Triantafyllou, Konstantinos, Gkolfakis, Paraskevas, Gralnek, Ian, Oakland, Kathryn, Manes, Gianpiero, Radaelli, Franco, Awadie, Halim, Camus Duboc, Marine, Christodoulou, Dimitrios D.K., Fedorov, Evgeny, Guy, Richard R.J., Hollenbach, Marcus, Ibrahim, Mostafa, Neeman, Ziv, Regge, Daniele, Rodriguez De Santiago, Enrique, Tham, Tony T.C., Thelin-Schmidt, Peter, Van Hooft, Jeanin J.E., Triantafyllou, Konstantinos, Gkolfakis, Paraskevas, Gralnek, Ian, Oakland, Kathryn, Manes, Gianpiero, Radaelli, Franco, Awadie, Halim, Camus Duboc, Marine, Christodoulou, Dimitrios D.K., Fedorov, Evgeny, Guy, Richard R.J., Hollenbach, Marcus, Ibrahim, Mostafa, Neeman, Ziv, Regge, Daniele, Rodriguez De Santiago, Enrique, Tham, Tony T.C., Thelin-Schmidt, Peter, and Van Hooft, Jeanin J.E.

Abstract

In the above-mentioned article, the name of Enrique Rodriguez de Santiago has been corrected. This was corrected in the online version on June 17, 2021., SCOPUS: er.j, DecretOANoAutActif, info:eu-repo/semantics/published

Published
2021

20. Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Author

Triantafyllou, Konstantinos, Gkolfakis, Paraskevas, Gralnek, Ian, Oakland, Kathryn, Manes, Gianpiero, Radaelli, Franco, Awadie, Halim, Camus Duboc, Marine, Christodoulou, Dimitrios D.K., Fedorov, Evgeny, Guy, Richard R.J., Hollenbach, Marcus, Ibrahim, Mostafa, Neeman, Ziv, Regge, Daniele, Rodriquez De Santiago, Enrique, Tham, Tony T.C., Thelin-Schmidt, Peter, Van Hooft, Jeanin J.E., Triantafyllou, Konstantinos, Gkolfakis, Paraskevas, Gralnek, Ian, Oakland, Kathryn, Manes, Gianpiero, Radaelli, Franco, Awadie, Halim, Camus Duboc, Marine, Christodoulou, Dimitrios D.K., Fedorov, Evgeny, Guy, Richard R.J., Hollenbach, Marcus, Ibrahim, Mostafa, Neeman, Ziv, Regge, Daniele, Rodriquez De Santiago, Enrique, Tham, Tony T.C., Thelin-Schmidt, Peter, and Van Hooft, Jeanin J.E.

Abstract

Main Recommendations 1 ESGE recommends that the initial assessment of patients presenting with acute lower gastrointestinal bleeding should include: a history of co-morbidities and medications that promote bleeding; hemodynamic parameters; physical examination (including digital rectal examination); and laboratory markers. A risk score can be used to aid, but should not replace, clinician judgment. Strong recommendation, low quality evidence. 2 ESGE recommends that, in patients presenting with a self-limited bleed and no adverse clinical features, an Oakland score of ≤?8 points can be used to guide the clinician decision to discharge the patient for outpatient investigation. Strong recommendation, moderate quality evidence. 3 ESGE recommends, in hemodynamically stable patients with acute lower gastrointestinal bleeding and no history of cardiovascular disease, a restrictive red blood cell transfusion strategy, with a hemoglobin threshold of ≤?7?g/dL prompting red blood cell transfusion. A post-transfusion target hemoglobin concentration of 7-9?g/dL is desirable. Strong recommendation, low quality evidence. 4 ESGE recommends, in hemodynamically stable patients with acute lower gastrointestinal bleeding and a history of acute or chronic cardiovascular disease, a more liberal red blood cell transfusion strategy, with a hemoglobin threshold of ≤?8?g/dL prompting red blood cell transfusion. A post-transfusion target hemoglobin concentration of ≥?10?g/dL is desirable. Strong recommendation, low quality evidence. 5 ESGE recommends that, in patients with major acute lower gastrointestinal bleeding, colonoscopy should be performed sometime during their hospital stay because there is no high quality evidence that early colonoscopy influences patient outcomes. Strong recommendation, low quality of evidence. 6 ESGE recommends that patients with hemodynamic instability and suspected ongoing bleeding undergo computed tomography angiography before endoscopic or radiologic treatmen, SCOPUS: ar.j, DecretOANoAutActif, info:eu-repo/semantics/published

Published
2021

21. Correction: Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Author

Triantafyllou, Konstantinos, additional, Gkolfakis, Paraskevas, additional, Gralnek, Ian M., additional, Oakland, Kathryn, additional, Manes, Gianpiero, additional, Radaelli, Franco, additional, Awadie, Halim, additional, Camus Duboc, Marine, additional, Christodoulou, Dimitrios, additional, Fedorov, Evgeny, additional, Guy, Richard J., additional, Hollenbach, Marcus, additional, Ibrahim, Mostafa, additional, Neeman, Ziv, additional, Regge, Daniele, additional, Rodriguez de Santiago, Enrique, additional, Tham, Tony C., additional, Thelin-Schmidt, Peter, additional, and van Hooft, Jeanin E., additional

Published
2021
Full Text
View/download PDF

22. Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Author

Triantafyllou, Konstantinos, additional, Gkolfakis, Paraskevas, additional, Gralnek, Ian M., additional, Oakland, Kathryn, additional, Manes, Gianpiero, additional, Radaelli, Franco, additional, Awadie, Halim, additional, Camus Duboc, Marine, additional, Christodoulou, Dimitrios, additional, Fedorov, Evgeny, additional, Guy, Richard J., additional, Hollenbach, Marcus, additional, Ibrahim, Mostafa, additional, Neeman, Ziv, additional, Regge, Daniele, additional, Rodriguez de Santiago, Enrique, additional, Tham, Tony C., additional, Thelin-Schmidt, Peter, additional, and van Hooft, Jeanin E., additional

Published
2021
Full Text
View/download PDF

24. Experimental evidence of effective human–AI collaboration in medical decision-making.

Author

Reverberi, Carlo, Rigon, Tommaso, Solari, Aldo, Hassan, Cesare, Cherubini, Paolo, GI Genius CADx Study Group, Antonelli, Giulio, Awadie, Halim, Bernhofer, Sebastian, Carballal, Sabela, Dinis-Ribeiro, Mário, Fernández-Clotett, Agnès, Esparrach, Glòria Fernández, Gralnek, Ian, Higasa, Yuta, Hirabayashi, Taku, Hirai, Tatsuki, Iwatate, Mineo, Kawano, Miki, and Mader, Markus

Subjects
ARTIFICIAL intelligence, DECISION making, DEEP learning
Abstract

Artificial Intelligence (ai) systems are precious support for decision-making, with many applications also in the medical domain. The interaction between mds and ai enjoys a renewed interest following the increased possibilities of deep learning devices. However, we still have limited evidence-based knowledge of the context, design, and psychological mechanisms that craft an optimal human–ai collaboration. In this multicentric study, 21 endoscopists reviewed 504 videos of lesions prospectively acquired from real colonoscopies. They were asked to provide an optical diagnosis with and without the assistance of an ai support system. Endoscopists were influenced by ai ( O R = 3.05 ), but not erratically: they followed the ai advice more when it was correct ( O R = 3.48 ) than incorrect ( O R = 1.85 ). Endoscopists achieved this outcome through a weighted integration of their and the ai opinions, considering the case-by-case estimations of the two reliabilities. This Bayesian-like rational behavior allowed the human–ai hybrid team to outperform both agents taken alone. We discuss the features of the human–ai interaction that determined this favorable outcome. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

25. A novel AI device for real-time optical characterization of colorectal polyps.

Author

Biffi, Carlo, Salvagnini, Pietro, Dinh, Nhan Ngo, Hassan, Cesare, Sharma, Prateek, GI Genius CADx Study Group, Antonelli, Giulio, Awadie, Halim, Bernhofer, Sebastian, Carballal, Sabela, Dinis-Ribeiro, Mário, Fernández-Clotet, Agnès, Esparrach, Glòria Fernández, Gralnek, Ian, Higasa, Yuta, Hirabayashi, Taku, Hirai, Tatsuki, Iwatate, Mineo, Kawano, Miki, and Mader, Markus

Subjects
RESEARCH, COLON polyps, CONFIDENCE intervals, COLONOSCOPY, ARTIFICIAL intelligence, REGRESSION analysis, DIAGNOSTIC imaging, SURVEYS, MARKETING, COMPUTER-aided diagnosis, RECEIVER operating characteristic curves, ARTIFICIAL neural networks, LONGITUDINAL method, ALGORITHMS, VIDEO recording, PROBABILITY theory
Abstract

Accurate in-vivo optical characterization of colorectal polyps is key to select the optimal treatment regimen during colonoscopy. However, reported accuracies vary widely among endoscopists. We developed a novel intelligent medical device able to seamlessly operate in real-time using conventional white light (WL) endoscopy video stream without virtual chromoendoscopy (blue light, BL). In this work, we evaluated the standalone performance of this computer-aided diagnosis device (CADx) on a prospectively acquired dataset of unaltered colonoscopy videos. An international group of endoscopists performed optical characterization of each polyp acquired in a prospective study, blinded to both histology and CADx result, by means of an online platform enabling careful video assessment. Colorectal polyps were categorized by reviewers, subdivided into 10 experts and 11 non-experts endoscopists, and by the CADx as either "adenoma" or "non-adenoma". A total of 513 polyps from 165 patients were assessed. CADx accuracy in WL was found comparable to the accuracy of expert endoscopists (CADxWL/Exp; OR 1.211 [0.766–1.915]) using histopathology as the reference standard. Moreover, CADx accuracy in WL was found superior to the accuracy of non-expert endoscopists (CADxWL/NonExp; OR 1.875 [1.191–2.953]), and CADx accuracy in BL was found comparable to it (CADxBL/CADxWL; OR 0.886 [0.612–1.282]). The proposed intelligent device shows the potential to support non-expert endoscopists in systematically reaching the performances of expert endoscopists in optical characterization. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

27. Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2021

Author

Gralnek, Ian M., additional, Stanley, Adrian J., additional, Morris, A. John, additional, Camus, Marine, additional, Lau, James, additional, Lanas, Angel, additional, Laursen, Stig B., additional, Radaelli, Franco, additional, Papanikolaou, Ioannis S., additional, Cúrdia Gonçalves, Tiago, additional, Dinis-Ribeiro, Mario, additional, Awadie, Halim, additional, Braun, Georg, additional, de Groot, Nicolette, additional, Udd, Marianne, additional, Sanchez-Yague, Andres, additional, Neeman, Ziv, additional, and van Hooft, Jeanin E., additional

Published
2021
Full Text
View/download PDF

34. Clinical implications of decision making in colorectal polypectomy: an international survey of Western endoscopists suggests priorities for change

Author

Tate, David J., additional, Desomer, Lobke, additional, Heitman, Steven J., additional, Forbes, Nauzer, additional, Burgess, Nicholas G., additional, Awadie, Halim, additional, Gralnek, Ian M., additional, Geldof, Jeroen, additional, De Looze, Danny, additional, Rex, Douglas, additional, Anderson, John, additional, and Bourke, Michael J., additional

Published
2020
Full Text
View/download PDF

36. Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019

Author

Hassan, Cesare, additional, East, James, additional, Radaelli, Franco, additional, Spada, Cristiano, additional, Benamouzig, Robert, additional, Bisschops, Raf, additional, Bretthauer, Michael, additional, Dekker, E., additional, Dinis-Ribeiro, Mario, additional, Ferlitsch, Monika, additional, Fuccio, Lorenzo, additional, Awadie, Halim, additional, Gralnek, Ian, additional, Jover, Rodrigo, additional, Kaminski, Michal F., additional, Pellisé, Maria, additional, Triantafyllou, Konstantinos, additional, Vanella, Giuseppe, additional, Mangas-Sanjuan, Carolina, additional, Frazzoni, Leonardo, additional, Van Hooft, Jeanin E., additional, and Dumonceau, Jean-Marc, additional

Published
2019
Full Text
View/download PDF

42. Mo1099 LONG TERM RATES OF SURGERY AND ADENOMA RECURRENCE ARE SIMILAR FOR LATERALLY SPREADING LESIONS RESECTED EN BLOC OR BY PIECEMEAL ENDOSCOPIC MUCOSAL RESECTION

Author

Tate, David J., primary, Awadie, Halim, additional, Desomer, Lobke, additional, Sidhu, Mayenaaz, additional, Burgess, Nicholas G., additional, Hourigan, Luke F., additional, Moss, Alan, additional, Raftopoulos, Spiro, additional, Singh, Rajvinder, additional, Brown, Gregor J., additional, and Bourke, Michael J., additional

Published
2018
Full Text
View/download PDF

43. Mo1662 SMSA-EMR SCORE IS A NOVEL ENDOSCOPIC RISK ASSESSMENT TOOL FOR PREDICTING CRITICAL ENDOSCOPIC MUCOSAL RESECTION OUTCOMES

Author

Sidhu, Mayenaaz, primary, Tate, David J., additional, Desomer, Lobke, additional, Awadie, Halim, additional, Brown, Gregor J., additional, Hourigan, Luke F., additional, Singh, Rajvinder, additional, Zanati, Simon, additional, Moss, Alan, additional, Raftopoulos, Spiro, additional, Lee, Eric Y., additional, Burgess, Nicholas G., additional, Anderson, John, additional, and Bourke, Michael J., additional

Published
2018
Full Text
View/download PDF

45. The clinical significance and synchronous polyp burden of large (≥ 20 mm) sessile serrated polyps in patients without serrated polyposis syndrome

Author

Desomer, Lobke, additional, Tate, David J., additional, Jayanna, Mahesh, additional, Pellise, Maria, additional, Awadie, Halim, additional, Burgess, Nicholas G., additional, McLeod, Duncan, additional, Mahajan, Hema, additional, Lee, Eric Y. T., additional, Williams, Stephen J., additional, and Bourke, Michael J., additional

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results