Search

Your search keyword '"Auslander, Noam"' showing total 237 results
Start Over Author "Auslander, Noam"
237 results on '"Auslander, Noam"'

1. Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease

Author

Soldan, Samantha S., Su, Chenhe, Monaco, Maria Chiara, Yoon, Leena, Kannan, Toshitha, Zankharia, Urvi, Patel, Rishi J., Dheekollu, Jayaraju, Vladimirova, Olga, Dowling, Jack W., Thebault, Simon, Brown, Natalie, Clauze, Annaliese, Andrada, Frances, Feder, Andries, Planet, Paul J., Kossenkov, Andrew, Schäffer, Daniel E., Ohayon, Joan, Auslander, Noam, Jacobson, Steven, and Lieberman, Paul M.

Published
2024
Full Text
View/download PDF

9. Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

Author

Patkar, Sushant, Heselmeyer-Haddad, Kerstin, Auslander, Noam, Hirsch, Daniela, Camps, Jordi, Bronder, Daniel, Brown, Markus, Chen, Wei-Dong, Lokanga, Rachel, Wangsa, Darawalee, Wangsa, Danny, Hu, Yue, Lischka, Annette, Braun, Rüdiger, Emons, Georg, Ghadimi, B. Michael, Gaedcke, Jochen, Grade, Marian, Montagna, Cristina, Lazebnik, Yuri, Difilippantonio, Michael J., Habermann, Jens K., Auer, Gert, Ruppin, Eytan, and Ried, Thomas

Published
2021
Full Text
View/download PDF

15. Data from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Author

Indeglia, Alexandra, primary, Leung, Jessica C., primary, Miller, Sven A., primary, Leu, Julia I-Ju, primary, Dougherty, James F., primary, Clarke, Nicole L., primary, Kirven, Nicole A., primary, Shao, Chunlei, primary, Ke, Lei, primary, Lovell, Scott, primary, Barnoud, Thibaut, primary, Lu, David Y., primary, Lin, Cindy, primary, Kannan, Toshitha, primary, Battaile, Kevin P., primary, Yang, Tyler Hong Loong, primary, Batista Oliva, Isabela, primary, Claiborne, Daniel T., primary, Vogel, Peter, primary, Liu, Lijun, primary, Liu, Qin, primary, Nefedova, Yulia, primary, Cassel, Joel, primary, Auslander, Noam, primary, Kossenkov, Andrew V., primary, Karanicolas, John, primary, and Murphy, Maureen E., primary

Published
2023
Full Text
View/download PDF

16. Table S3 from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Author

Indeglia, Alexandra, primary, Leung, Jessica C., primary, Miller, Sven A., primary, Leu, Julia I-Ju, primary, Dougherty, James F., primary, Clarke, Nicole L., primary, Kirven, Nicole A., primary, Shao, Chunlei, primary, Ke, Lei, primary, Lovell, Scott, primary, Barnoud, Thibaut, primary, Lu, David Y., primary, Lin, Cindy, primary, Kannan, Toshitha, primary, Battaile, Kevin P., primary, Yang, Tyler Hong Loong, primary, Batista Oliva, Isabela, primary, Claiborne, Daniel T., primary, Vogel, Peter, primary, Liu, Lijun, primary, Liu, Qin, primary, Nefedova, Yulia, primary, Cassel, Joel, primary, Auslander, Noam, primary, Kossenkov, Andrew V., primary, Karanicolas, John, primary, and Murphy, Maureen E., primary

Published
2023
Full Text
View/download PDF

17. Supplementary Figures S1-S8 from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Author

Indeglia, Alexandra, primary, Leung, Jessica C., primary, Miller, Sven A., primary, Leu, Julia I-Ju, primary, Dougherty, James F., primary, Clarke, Nicole L., primary, Kirven, Nicole A., primary, Shao, Chunlei, primary, Ke, Lei, primary, Lovell, Scott, primary, Barnoud, Thibaut, primary, Lu, David Y., primary, Lin, Cindy, primary, Kannan, Toshitha, primary, Battaile, Kevin P., primary, Yang, Tyler Hong Loong, primary, Batista Oliva, Isabela, primary, Claiborne, Daniel T., primary, Vogel, Peter, primary, Liu, Lijun, primary, Liu, Qin, primary, Nefedova, Yulia, primary, Cassel, Joel, primary, Auslander, Noam, primary, Kossenkov, Andrew V., primary, Karanicolas, John, primary, and Murphy, Maureen E., primary

Published
2023
Full Text
View/download PDF

20. An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Author

Indeglia, Alexandra, primary, Leung, Jessica C., additional, Miller, Sven A., additional, Leu, Julia I-Ju, additional, Dougherty, James F., additional, Clarke, Nicole L., additional, Kirven, Nicole A., additional, Shao, Chunlei, additional, Ke, Lei, additional, Lovell, Scott, additional, Barnoud, Thibaut, additional, Lu, David Y., additional, Lin, Cindy, additional, Kannan, Toshitha, additional, Battaile, Kevin P., additional, Yang, Tyler Hong Loong, additional, Batista Oliva, Isabela, additional, Claiborne, Daniel T., additional, Vogel, Peter, additional, Liu, Lijun, additional, Liu, Qin, additional, Nefedova, Yulia, additional, Cassel, Joel, additional, Auslander, Noam, additional, Kossenkov, Andrew V., additional, Karanicolas, John, additional, and Murphy, Maureen E., additional

Published
2023
Full Text
View/download PDF

21. Figure S1 from Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Author

Emons, Georg, primary, Spitzner, Melanie, primary, Reineke, Sebastian, primary, Möller, Janneke, primary, Auslander, Noam, primary, Kramer, Frank, primary, Hu, Yue, primary, Beissbarth, Tim, primary, Wolff, Hendrik A., primary, Rave-Fränk, Margret, primary, Heßmann, Elisabeth, primary, Gaedcke, Jochen, primary, Ghadimi, B. Michael, primary, Johnsen, Steven A., primary, Ried, Thomas, primary, and Grade, Marian, primary

Published
2023
Full Text
View/download PDF

22. Table S3 from Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Author

Emons, Georg, primary, Spitzner, Melanie, primary, Reineke, Sebastian, primary, Möller, Janneke, primary, Auslander, Noam, primary, Kramer, Frank, primary, Hu, Yue, primary, Beissbarth, Tim, primary, Wolff, Hendrik A., primary, Rave-Fränk, Margret, primary, Heßmann, Elisabeth, primary, Gaedcke, Jochen, primary, Ghadimi, B. Michael, primary, Johnsen, Steven A., primary, Ried, Thomas, primary, and Grade, Marian, primary

Published
2023
Full Text
View/download PDF

23. Data from Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Author

Emons, Georg, primary, Spitzner, Melanie, primary, Reineke, Sebastian, primary, Möller, Janneke, primary, Auslander, Noam, primary, Kramer, Frank, primary, Hu, Yue, primary, Beissbarth, Tim, primary, Wolff, Hendrik A., primary, Rave-Fränk, Margret, primary, Heßmann, Elisabeth, primary, Gaedcke, Jochen, primary, Ghadimi, B. Michael, primary, Johnsen, Steven A., primary, Ried, Thomas, primary, and Grade, Marian, primary

Published
2023
Full Text
View/download PDF

24. Supplementary Figure and Table Legends from Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Author

Emons, Georg, primary, Spitzner, Melanie, primary, Reineke, Sebastian, primary, Möller, Janneke, primary, Auslander, Noam, primary, Kramer, Frank, primary, Hu, Yue, primary, Beissbarth, Tim, primary, Wolff, Hendrik A., primary, Rave-Fränk, Margret, primary, Heßmann, Elisabeth, primary, Gaedcke, Jochen, primary, Ghadimi, B. Michael, primary, Johnsen, Steven A., primary, Ried, Thomas, primary, and Grade, Marian, primary

Published
2023
Full Text
View/download PDF

25. Supplementary Text from Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response

Author

Braun, Rüdiger, primary, Anthuber, Lena, primary, Hirsch, Daniela, primary, Wangsa, Darawalee, primary, Lack, Justin, primary, McNeil, Nicole E., primary, Heselmeyer-Haddad, Kerstin, primary, Torres, Irianna, primary, Wangsa, Danny, primary, Brown, Markus A., primary, Tubbs, Anthony, primary, Auslander, Noam, primary, Gertz, E. Michael, primary, Brauer, Philip R., primary, Cam, Margaret C., primary, Sackett, Dan L., primary, Habermann, Jens K., primary, Nussenzweig, Andre, primary, Ruppin, Eytan, primary, Zhang, Zhongqiu, primary, Rosenberg, Daniel W., primary, and Ried, Thomas, primary

Published
2023
Full Text
View/download PDF

26. Figure S7 from Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response

Author

Braun, Rüdiger, primary, Anthuber, Lena, primary, Hirsch, Daniela, primary, Wangsa, Darawalee, primary, Lack, Justin, primary, McNeil, Nicole E., primary, Heselmeyer-Haddad, Kerstin, primary, Torres, Irianna, primary, Wangsa, Danny, primary, Brown, Markus A., primary, Tubbs, Anthony, primary, Auslander, Noam, primary, Gertz, E. Michael, primary, Brauer, Philip R., primary, Cam, Margaret C., primary, Sackett, Dan L., primary, Habermann, Jens K., primary, Nussenzweig, Andre, primary, Ruppin, Eytan, primary, Zhang, Zhongqiu, primary, Rosenberg, Daniel W., primary, and Ried, Thomas, primary

Published
2023
Full Text
View/download PDF

27. Supplementary Materials and Methods from Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Author

Dattilo, Rosanna, primary, Mottini, Carla, primary, Camera, Emanuela, primary, Lamolinara, Alessia, primary, Auslander, Noam, primary, Doglioni, Ginevra, primary, Muscolini, Michela, primary, Tang, Wei, primary, Planque, Melanie, primary, Ercolani, Cristiana, primary, Buglioni, Simonetta, primary, Manni, Isabella, primary, Trisciuoglio, Daniela, primary, Boe, Alessandra, primary, Grande, Sveva, primary, Luciani, Anna Maria, primary, Iezzi, Manuela, primary, Ciliberto, Gennaro, primary, Ambs, Stefan, primary, De Maria, Ruggero, primary, Fendt, Sarah-Maria, primary, Ruppin, Eytan, primary, and Cardone, Luca, primary

Published
2023
Full Text
View/download PDF

28. Data from Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response

Author

Braun, Rüdiger, primary, Anthuber, Lena, primary, Hirsch, Daniela, primary, Wangsa, Darawalee, primary, Lack, Justin, primary, McNeil, Nicole E., primary, Heselmeyer-Haddad, Kerstin, primary, Torres, Irianna, primary, Wangsa, Danny, primary, Brown, Markus A., primary, Tubbs, Anthony, primary, Auslander, Noam, primary, Gertz, E. Michael, primary, Brauer, Philip R., primary, Cam, Margaret C., primary, Sackett, Dan L., primary, Habermann, Jens K., primary, Nussenzweig, Andre, primary, Ruppin, Eytan, primary, Zhang, Zhongqiu, primary, Rosenberg, Daniel W., primary, and Ried, Thomas, primary

Published
2023
Full Text
View/download PDF

29. Supplementary Data from Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Author

Dattilo, Rosanna, primary, Mottini, Carla, primary, Camera, Emanuela, primary, Lamolinara, Alessia, primary, Auslander, Noam, primary, Doglioni, Ginevra, primary, Muscolini, Michela, primary, Tang, Wei, primary, Planque, Melanie, primary, Ercolani, Cristiana, primary, Buglioni, Simonetta, primary, Manni, Isabella, primary, Trisciuoglio, Daniela, primary, Boe, Alessandra, primary, Grande, Sveva, primary, Luciani, Anna Maria, primary, Iezzi, Manuela, primary, Ciliberto, Gennaro, primary, Ambs, Stefan, primary, De Maria, Ruggero, primary, Fendt, Sarah-Maria, primary, Ruppin, Eytan, primary, and Cardone, Luca, primary

Published
2023
Full Text
View/download PDF

30. Data from Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Author

Dattilo, Rosanna, primary, Mottini, Carla, primary, Camera, Emanuela, primary, Lamolinara, Alessia, primary, Auslander, Noam, primary, Doglioni, Ginevra, primary, Muscolini, Michela, primary, Tang, Wei, primary, Planque, Melanie, primary, Ercolani, Cristiana, primary, Buglioni, Simonetta, primary, Manni, Isabella, primary, Trisciuoglio, Daniela, primary, Boe, Alessandra, primary, Grande, Sveva, primary, Luciani, Anna Maria, primary, Iezzi, Manuela, primary, Ciliberto, Gennaro, primary, Ambs, Stefan, primary, De Maria, Ruggero, primary, Fendt, Sarah-Maria, primary, Ruppin, Eytan, primary, and Cardone, Luca, primary

Published
2023
Full Text
View/download PDF

31. Supplementary Tables and Figures from Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Author

Dattilo, Rosanna, primary, Mottini, Carla, primary, Camera, Emanuela, primary, Lamolinara, Alessia, primary, Auslander, Noam, primary, Doglioni, Ginevra, primary, Muscolini, Michela, primary, Tang, Wei, primary, Planque, Melanie, primary, Ercolani, Cristiana, primary, Buglioni, Simonetta, primary, Manni, Isabella, primary, Trisciuoglio, Daniela, primary, Boe, Alessandra, primary, Grande, Sveva, primary, Luciani, Anna Maria, primary, Iezzi, Manuela, primary, Ciliberto, Gennaro, primary, Ambs, Stefan, primary, De Maria, Ruggero, primary, Fendt, Sarah-Maria, primary, Ruppin, Eytan, primary, and Cardone, Luca, primary

Published
2023
Full Text
View/download PDF

34. Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells

Author

Soldan, Samantha, primary, Su, Chenhe, additional, Monaco, Maria Chiara, additional, Brown, Natalie, additional, Clauze, Annaliese, additional, Andrada, Frances, additional, Feder, Andries, additional, Planet, Paul, additional, Kossenkov, Andrew, additional, Schäffer, Daniel, additional, Ohayon, Joan, additional, Auslander, Noam, additional, Jacobson, Steve, additional, and Lieberman, Paul, additional

Published
2023
Full Text
View/download PDF

36. Abstract C023: A microbiome-produced metabolite drives immunostimulatory macrophages and boosts response to immune checkpoint inhibitors in pancreatic cancer

Author

Mirji, Gauri, primary, Worth, Alison, additional, Bhat, Sajad, additional, Sayed, Mohamed, additional, Kannan, Toshitha, additional, Goldman, Aaron, additional, Tang, Hsin-Yao, additional, Liu, Qin, additional, Auslander, Noam, additional, Dang, Chi, additional, Abdel-Mohsen, Mohamed, additional, Kossenkov, Andrew, additional, Stanger, Ben, additional, and Shinde, Rahul, additional

Published
2022
Full Text
View/download PDF

37. 1307 The microbiome-derived metabolite TMAO drives immune activation and boosts response to immune checkpoint blockade in pancreatic cancer

Author

Mirji, Gauri, primary, Worth, Alison, additional, Bhat, Sajad, additional, Sayed, Mohamed El, additional, Kannan, Toshitha, additional, Goldman, Aaron, additional, Tang, Hsin Yao, additional, Liu, Qin, additional, Auslander, Noam, additional, Dang, Chi, additional, Abdel-Mohsen, Mohamed, additional, Kossenkov, Andrew, additional, Stanger, Ben, additional, and Shinde, Rahul, additional

Published
2022
Full Text
View/download PDF

38. The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer

Author

Mirji, Gauri, primary, Worth, Alison, additional, Bhat, Sajad Ahmad, additional, El Sayed, Mohamed, additional, Kannan, Toshitha, additional, Goldman, Aaron R., additional, Tang, Hsin-Yao, additional, Liu, Qin, additional, Auslander, Noam, additional, Dang, Chi V., additional, Abdel-Mohsen, Mohamed, additional, Kossenkov, Andrew, additional, Stanger, Ben Z., additional, and Shinde, Rahul S., additional

Published
2022
Full Text
View/download PDF

39. Mutated Processes Predict Immune Checkpoint Inhibitor Therapy Benefit in Metastatic Melanoma

Author

Patterson Andrew, Auslander Noam

Abstract

Immune Checkpoint Inhibitor (ICI) therapy has revolutionized treatment for advanced melanoma; however, only a subset of patients benefit from this treatment. Despite considerable efforts, the Tumor Mutation Burden (TMB) is the only FDA-approved biomarker in melanoma. However, the mechanisms underlying TMB association with prolonged ICI survival are not entirely understood and may depend on numerous confounding factors. To identify more interpretable ICI response biomarkers based on tumor mutations, wetrainclassifiers using mutations within distinct biological processes. Weevaluatea variety of feature selection and classification methods andidentifykey mutated biological processes that provide improved predictive capability compared to the TMB. The top mutated processeswe identifyare leukocyte and T-cell proliferation regulation, which demonstrate stable predictive performance across different data cohorts of melanoma patients treated with ICI. This studyprovides machine learning basedbiologically interpretable genomic predictors of ICI response with substantially improved predictive performance over the TMB.&nbsp

Published
2022
Full Text
View/download PDF

44. Incorporating Machine Learning Into Bioinformatics Frameworks

Author

Auslander, Noam, Gussow, Ayal, and Koonin, Eugene

Subjects
anatomy_morphology
Abstract

The exponential growth of biomedical data in recent years urged the application of numerous machine learning techniques to address emerging problems in biology and clinical research. By enabling automatic feature extraction, selection and generation of predictive models, these methods can be used to efficiently study complex biological systems. Machine learning techniques are frequently integrated with bioinformatic methods, as well as curated databases and biological networks, to enhance training and validation, identify the best interpretable features, and enable feature and model investigation. Here, we review recently developed methods that incorporate machine learning within the same framework with techniques from molecular evolution, protein structure analysis, systems biology and disease genomics. We outline the challenges posed for machine learning, and in particular, deep learning in biomedicine and suggest unique opportunities for machine learning techniques integrated with established bioinformatics approaches to overcome some of these challenges.

Published
2021

45. Additional file 9 of Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

Author

Sushant Patkar, Heselmeyer-Haddad, Kerstin, Auslander, Noam, Hirsch, Daniela, Camps, Jordi, Bronder, Daniel, Brown, Markus, Chen, Wei-Dong, Lokanga, Rachel, Darawalee Wangsa, Wangsa, Danny, Hu, Yue, Lischka, Annette, Braun, Rüdiger, Emons, Georg, B. Michael Ghadimi, Gaedcke, Jochen, Grade, Marian, Montagna, Cristina, Lazebnik, Yuri, Difilippantonio, Michael J., Habermann, Jens K., Auer, Gert, Ruppin, Eytan, and Ried, Thomas

Abstract

Additional file 9: Figure S2. Scatter plots showing the relationship between chromosome arm imbalance scores in cancer (Cancer_AN) and normal gene expression (Normal_GE) for each tissue/tumor type.

Published
2021
Full Text
View/download PDF

46. Additional file 5 of Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

Author

Sushant Patkar, Heselmeyer-Haddad, Kerstin, Auslander, Noam, Hirsch, Daniela, Camps, Jordi, Bronder, Daniel, Brown, Markus, Chen, Wei-Dong, Lokanga, Rachel, Darawalee Wangsa, Wangsa, Danny, Hu, Yue, Lischka, Annette, Braun, Rüdiger, Emons, Georg, B. Michael Ghadimi, Gaedcke, Jochen, Grade, Marian, Montagna, Cristina, Lazebnik, Yuri, Difilippantonio, Michael J., Habermann, Jens K., Auer, Gert, Ruppin, Eytan, and Ried, Thomas

Abstract

Additional file 5: Figure S1. Scatter plots correlating chromosome arm imbalance scores (X axes) with arm-wide expression levels in cancer (upper row, Y axes) and normal tissue (lower row, Y-axes).

Published
2021
Full Text
View/download PDF

47. Additional file 10 of Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

Author

Sushant Patkar, Heselmeyer-Haddad, Kerstin, Auslander, Noam, Hirsch, Daniela, Camps, Jordi, Bronder, Daniel, Brown, Markus, Chen, Wei-Dong, Lokanga, Rachel, Darawalee Wangsa, Wangsa, Danny, Hu, Yue, Lischka, Annette, Braun, Rüdiger, Emons, Georg, B. Michael Ghadimi, Gaedcke, Jochen, Grade, Marian, Montagna, Cristina, Lazebnik, Yuri, Difilippantonio, Michael J., Habermann, Jens K., Auer, Gert, Ruppin, Eytan, and Ried, Thomas

Abstract

Additional file 10: Figure S3. Scatter plots showing the relationship between chromosome arm imbalance scores in cancer (Cancer_AN) and normal gene expression (Normal_GE) for each chromosome arm.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results