1,404 results on '"Augustijns, Patrick"'
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2. Characterization of luminal contents from the fasted human proximal colon
3. A quantification of gastric and duodenal fluid volumes in older adults using MRI
4. Investigating the effect of whey and casein proteins on drug solubility from a paediatric drug absorption perspective
5. β-D-N4-hydroxycytidine (NHC, EIDD-1931) inhibits chikungunya virus replication in mosquito cells and ex vivo Aedes aegypti guts, but not when ingested during blood-feeding
6. Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients
7. Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates
8. Dissolution, phase behavior and mass transport of amorphous solid dispersions in aspirated human intestinal fluids
9. Tofacitinib in Pregnancy: Assessing Pregnancy and Infant Outcomes, Cord Blood, and Breast Milk Concentrations
10. Drug Dissolution in Oral Drug Absorption: Workshop Report
11. The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs
12. The impact of advanced age on gastrointestinal characteristics that are relevant to oral drug absorption: An AGePOP review
13. Characterization of neonatal and infant enterostomy fluids - part II: Drug solubility
14. Assessment of food effects during clinical development
15. Effect of sleeve gastrectomy and Roux-en-Y gastric bypass on gastrointestinal physiology
16. Physiologically Based Pharmacokinetic (PBPK) Modelling of Oral Drug Absorption in Older Adults – an AGePOP review
17. The impact of inflammation on the expression of drug transporters and metabolic enzymes in colonic tissue from ulcerative colitis patients
18. The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern
19. An Assessment of Occasional Bio-Inequivalence for BCS1 and BCS3 Drugs: What are the Underlying Reasons?
20. Favipiravir at high doses has potent antiviral activity in SARS-CoV-2–infected hamsters, whereas hydroxychloroquine lacks activity
21. Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
22. Adaptations in gastrointestinal physiology after sleeve gastrectomy and Roux-en-Y gastric bypass
23. Insight into the Colonic Disposition of Sulindac in Humans
24. Development of a HILIC-MS/MS method for the quantification of histamine and its main metabolites in human urine samples
25. Biorelevant Two-Stage In Vitro Testing for rDCS Classification and in PBPK Modeling–Case Example Ritonavir
26. Biopredictive in vitro testing methods to assess intestinal drug absorption from supersaturating dosage forms
27. Tofacitinib in pregnancy: Assessing Pregnancy and Infant Outcomes, Cord Blood and Breast Milk Concentrations
28. Β-D-N 4-Hydroxycytidine (NHC, EIDD-1931) Inhibits Chikungunya Virus Replication in Mosquito Cells and Ex Vivo Aedes Aegypti Guts, But Not When Ingested During Blood-Feeding
29. Local immune response to food antigens drives meal-induced abdominal pain
30. Co-existing colloidal phases of human duodenal aspirates: Intraindividual fluctuations and interindividual variability in relation to molecular composition
31. Predicting iron absorption from an effervescent iron supplement in obese patients before and after Roux-en-Y gastric bypass: a preliminary study
32. Understanding the gastrointestinal tract in obesity: From gut motility patterns to enzyme secretion.
33. Enzymatic prodrug degradation in the fasted and fed small intestine: in vitro studies and interindividual variability in human aspirates
34. Challenges in Permeability Assessment for Oral Drug Product Development
35. Correction: Van der Veken et al. Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study. Pharmaceutics 2022, 14, 1935
36. Extra collagen overlay prolongs the differentiated phenotype in sandwich-cultured rat hepatocytes
37. The effect of 2-hydroxypropyl-β-cyclodextrin on the intestinal permeation through mucus
38. Assessment of Passive Intestinal Permeability Using an Artificial Membrane Insert System
39. Corrigendum to “The effect of esomeprazole on the upper GI tract release and systemic absorption of mesalazine from colon targeted formulations” [Int. J. Pharm. 619 (2022) 121701]
40. Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding
41. Tofacitinib concentrations in plasma and breastmilk of a lactating woman with ulcerative colitis
42. Flexible nano- and microliter injections on a single liquid chromatography–mass spectrometry system: Minimizing sample preparation and maximizing linear dynamic range
43. Development of a sensitive and quantitative UHPLC-MS/MS method to study the whole-body uptake of pharmaceuticals in zebrafish
44. The Effect of Sparkling Water on Intraluminal Formulation Behavior and Systemic Drug Performance
45. Micronutrient intake, from diet and supplements, and association with status markers in pre- and post-RYGB patients
46. Trapping magnetic nanoparticles for in-line capillary electrophoresis in a liquid based capillary coolant system
47. The dynamic gastric environment and its impact on drug and formulation behaviour
48. Approaches to Account for Colon Absorption in Physiologically Based Biopharmaceutics Modeling of Extended-Release Drug Products.
49. Development and complications of nutritional deficiencies after bariatric surgery.
50. In vitro evaluation of the impact of gastrointestinal transfer on luminal performance of commercially available products of posaconazole and itraconazole using BioGIT
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