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5. Additional file 9 of Transcriptome of the synganglion in the tick Ixodes ricinus and evolution of the cys-loop ligand-gated ion channel family in ticks

Author

Rispe, Claude, Hervet, Caroline, de la Cotte, Nathalie, Daveu, Romain, Labadie, Karine, Noel, Benjamin, Aury, Jean-Marc, Thany, Steeve, Taillebois, Emiliane, Cartereau, Alison, Le Mauff, Anaïs, Charvet, Claude L., Auger, Clément, Courtot, Elise, Neveu, Cédric, and Plantard, Olivier

Abstract

Additional file 9: Figure S3. Maximum-likelihood phylogenetic trees of different sub-groups of cys-loop LGICs. Phylogenies includes sequences from different ticks species (labels and branches in blue) and other arthropods: P. tepidariorum (house spider), Acariformes, Parasitiformes, and D. melanogaster. Labels indicate accession numbers of protein sequences and species name. Accessions of I. ricinus are listed in Table S6. Filled circles on branches indicate bootstrap support (support increases with circle width, ranging from 80 to 100). Trees were rooted based on the complete phylogeny (Fig. 5). A: GABA group, B: «Insect group 1», C: pHCL, D: GluCls, E: Gly, F: His.

Published
2022
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6. Additional file 7 of Transcriptome of the synganglion in the tick Ixodes ricinus and evolution of the cys-loop ligand-gated ion channel family in ticks

Author

Rispe, Claude, Hervet, Caroline, de la Cotte, Nathalie, Daveu, Romain, Labadie, Karine, Noel, Benjamin, Aury, Jean-Marc, Thany, Steeve, Taillebois, Emiliane, Cartereau, Alison, Le Mauff, Anaïs, Charvet, Claude L., Auger, Clément, Courtot, Elise, Neveu, Cédric, and Plantard, Olivier

Abstract

Additional file 7: Figure S1. Genomic structure of the gene GABA-1-Rdl, with three predicted isoforms and their relative expression. A: Reannotation of the gene XP_042145571.1 located on a genomic scaffold of Ixodes scapularis, NW_024609839.1. The gene (drawing not to scale) has a span of ~247 kbp, on a scaffold of ~92 Mbp. The whole gene is on the minus frame. Boxes correspond to exons. Grey-filled boxes correspond to exons which we consider incorrect (over-predictions in both cases, based on the conserved sequence of GABA-1-Rdl) and by comparison with the homologous sequence in other tick species. Exons in blue correspond to a predicted triplication of one exon (exon 7a, 7b, 7c), whereas only one exon (7b) was annotated for XP_042145571.1. For each numbered exon, the positions indicate the start and end. Numbers followed by a star correspond to reannotations and differ from the published sequence. The translated sequence of each exon is given. B: Alignment of the translated sequences for the three alternative exons 7, including both the sequences for I. scapularis based on our reannotation and the homologous sequences from the I. ricinus alternative transcripts identified in the synganglion transcriptome (this study). Two trans-membrane domaines are indicated, and an arrow shows the A->S mutations known to confer resistance to dieldrin. C: Relative expression (y-axis) of the three isoforms of GABA-1-Rdl. Expressions was counted as counts per millions with RSEM, and normalized to evaluate relative expression. In x-axis, different synganglion libraries produced in this study (described in Table 4). In blue, red and yellow, estimated relative expression of exon 7a, 7b and 7c respectively.

Published
2022
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7. Additional file 8 of Transcriptome of the synganglion in the tick Ixodes ricinus and evolution of the cys-loop ligand-gated ion channel family in ticks

Author

Rispe, Claude, Hervet, Caroline, de la Cotte, Nathalie, Daveu, Romain, Labadie, Karine, Noel, Benjamin, Aury, Jean-Marc, Thany, Steeve, Taillebois, Emiliane, Cartereau, Alison, Le Mauff, Anaïs, Charvet, Claude L., Auger, Clément, Courtot, Elise, Neveu, Cédric, and Plantard, Olivier

Abstract

Additional file 8: Figure S2. Genomic organization of Histamine-gated-like sequences in Ixodes scapularis. We used the Histamine gated-like sequences obtained from our meta-transcriptome of Ixodes ricinus to search homologous genes in I. scapularis (homology inferred from near-identity of protein sequences), and to locate them on the genome. The figure shows the entire scaffold NW_024609883 (109.621.045 bp) from the I. scapularis genome, which has homologs to His1 to His12 in I. ricinus. The upper scale indicates positions in Mbp. The lower scale represents a focus on a smaller region containing clusters of His-like sequences, with a scale in Kbp. Annotated genes and their orientations are indicated by filled triangles, with below, the accession of the protein sequence in I. scapularis, and the name of its homologous sequence in I. ricinus (this study). A star indicates that the gene model is probably incorrect: XP_042142979 matches with His1 only over the first four exons, while its remaining sequence appears to represent a chimeric fusion with a totally different gene, XP_040070355 is missing an N-term, XP_040070356 is incomplete and matches only the beginning of His3, whereas XP_040068404 matches only the end of His3 and is in opposite frame of XP_ 040070356 (we interpret this as a likely error of the genome assembly, the two accession probably representing respectively the start and end of the same gene). Open triangles indicate regions where no gene has been annotated in I. scapularis, but where we detected high similarities with I. ricinus genes (for His4 and His9 respectively). For His13 to His18, homologous regions were detected on different scaffolds.

Published
2022
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8. Additional file 10 of Transcriptome of the synganglion in the tick Ixodes ricinus and evolution of the cys-loop ligand-gated ion channel family in ticks

Author

Rispe, Claude, Hervet, Caroline, de la Cotte, Nathalie, Daveu, Romain, Labadie, Karine, Noel, Benjamin, Aury, Jean-Marc, Thany, Steeve, Taillebois, Emiliane, Cartereau, Alison, Le Mauff, Anaïs, Charvet, Claude L., Auger, Clément, Courtot, Elise, Neveu, Cédric, and Plantard, Olivier

Subjects
urogenital system
Abstract

Additional file 10: Figure S4. Concentration–response relationship of GABA on the I. ricinus RDL receptor expressed in Xenopus oocytes. A. Representative current traces of a single oocyte micro-injected with Iri-rdl cRNA perfused with increasing concentrations of GABA for 10 seconds (short bars). The concentration of GABA (μM) is indicated above each trace. B. Concentration–response curve for GABA on the Iri-RDL channel. All current responses are normalized to 300 μM and shown as the mean ± SEM.

Published
2022
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14. A first insight into the effect of Lotilaner on GABA-gated channels from the european tick Ixodes ricinus

Author

Auger, Clément, Rispe, Claude, Hervet, Caroline, Courtot, Elise, THANY, Steeve, Plantard, Olivier, Neveu, Cédric, and Charvet, Claude

Subjects
tique, résistance aux insecticides, fungi, parasitic diseases, Microbiology and Parasitology, ixodes ricinus, canal ionique, Microbiologie et Parasitologie, récepteur gaba
Abstract

Ticks are strict blood-feeding arthropods (Acari), which represent a major health issue for wild or domesticated animals and humans, due to their potential to transmit disease agents. Control of ticks is increasingly difficult due to the development of drug-resistant parasites. Ligand-gated ion channels of the tick central nervous system are the primary targets of acaricides. Among those receptors, the γ-aminobutyric acid-gated chloride ion channels (GABACls) are the main synaptic inhibitory receptors. Lotilaner is a recently developed parasiticide from the isoxazoline chemical class that was shown to be a non-competitive antagonist of GABACls from the livestock tick Rhipicephalus microplus. In the present study, we characterized the GABACls from the European tick species Ixodes ricinus. We extracted RNAs from Ixodes ricinus nymphs. Taking advantage of the phylogenetic closeness of I. ricinus and R. microplus in the Arthropoda phylum, we identified the I. ricinus GABACl subunit homologue. The cDNA encoding the Iri- GABACl was cloned and the corresponding in vitro synthesized cRNAs were micro-injected into Xenopus laevis oocytes to investigate its pharmacological properties. Functional expression and two-electrode voltage clamp studies demonstrated that the GABACl subunit formed a homomeric receptor gated by GABA. Importantly, the insecticides like lotilaner, fipronil and picrotoxin efficiently blocked the GABA currents as previously observed for the R. microplus GABACl. Surprisingly, I. ricinus GABACl was not sensitive to the pesticide dieldrin, suggesting a potential naturally existing resistance mechanism involving alternative exons. Here we report the functional characterization of the first GABACl of I. ricinus demonstrating that it is an important molecular target for lotilaner. Transcriptomic analysis of I. ricinus are in progress to identify new acaricidal targets.

Published
2019

15. Caractériser les neurorécepteurs de tiques pour le développement de nouveaux acaricides plus spécifiques et durables : le projet Xenobio-Tick

Author

Plantard, Olivier, Rispe, Claude, Thany, Steeve, Charvet, Claude, Courtot, Elise, Auger, Clément, Neveu, Cédric, Biologie, Epidémiologie et analyse de risque en Santé Animale (BIOEPAR), Institut National de la Recherche Agronomique (INRA), Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), Institut National de la Recherche Agronomique (INRA)-Université d'Orléans (UO), Infectiologie et Santé Publique (UMR ISP), Institut National de la Recherche Agronomique (INRA)-Université de Tours, Institut Carnot France Future Elevage, and Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT)

Subjects
tique, caractérisation fonctionnelle, transcriptomique, acaricide, [SDV.BA]Life Sciences [q-bio]/Animal biology, neurorécepteur, ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2018

16. Receding-Horizon Pseudo-spectral Control of Wave Energy Converters Using Periodic Basis Functions

Author

Auger, Clément, Mérigaud, Alexis, Ringwood, John, Auger, Clément, Mérigaud, Alexis, and Ringwood, John

Abstract

Power-maximising control of wave energy converters (WECs) can be implemented within a receding-horizon (RH) framework, whereby the reference force or velocity trajectory is updated in real-time by a feed-forward control (FFC) algorithm. For the computation of optimal WEC trajectories and control forces, Fourier pseudo-spectral (PS) control, using periodic basis functions, is simple and computationally attractive, for both linear and non-linear WEC dynamics. However, the finite-length wave excitation signal, as seen by the FFC, is in general nonperiodic. In this paper, it is shown that, despite the nonperiodicity of the input wave signal, a simple Fourier PS method can be successfully used as a FFC algorithm, by applying suitable windowing functions to the input signal when necessary. Furthermore, a simple wave forecasting algorithm is introduced, solely based on past values of the wave excitation, and the impact of wave forecast errors on the controller performance is investigated. Overall, with or without forecast errors, the proposed approach allows for power absorption above 99% of the optimum, for a forecasting horizon of less than 30 seconds for a linear WEC model, and less than 15 seconds for a non-linear WEC model including a quadratic viscous drag term.

Published
2018

17. Priuatus chez Horace et dans sa première réception, échos d'un mot

Author

Auger, Clément

Abstract

À partir des modalités de traitement du mot priuatus dans les dictionnaires de référence, cet article propose de dégager un balancement dans sa signification allant d’un sens vide (priuatus, « privé de ») à un sens plein (priuatus, « personne privée »). Il s’agit ensuite de voir comment deux commentateurs d’Horace ont travaillé le texte du poète lorsqu’il utilisait ce mot, pour le faire jouer entre ces deux pôles et le faire rendre son sens, voire pour en produire du nouveau.

Published
2017
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18. Deuil, dépression et mélancolie

Author

Auger, Clément, Recherches en Psychopathologie, nouveaux symptômes et lien social (EA 4050), Université de Poitiers-Université de Brest (UBO)-Université Catholique de l'Ouest (UCO)-Université de Rennes 2 (UR2), and Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)

Subjects
dépression, Deuil, [SHS.PSY]Humanities and Social Sciences/Psychology, mélancolie
Published
2010

19. Do patients have any special medical or rehabilitation difficulties after a craniectomy for malignant cerebral infarction during their hospitalization in a physical medicine and rehabilitation department?

Author

E. Guettard, Marie-Germaine Bousser, K. Vahedi, Alain Yelnik, Isabelle V. Bonan, N. Bradai, L. Mandon, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Service de neurologie [Univ. Paris VII], Université Paris Diderot - Paris 7 (UPD7)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Lariboisière-Université Paris Diderot - Paris 7 (UPD7), and Auger, Clément

Subjects
Male, Complications, medicine.medical_treatment, Brain Edema, Comorbidity, Accident vasculaire cérébral, Postoperative Complications, 0302 clinical medicine, Orthopedics and Sports Medicine, 030212 general & internal medicine, Stroke, Craniotomy, Encephalocele, Rehabilitation, Cerebral infarction, Infarction, Middle Cerebral Artery, Middle Aged, Functional Independence Measure, 3. Good health, Intracranial Embolism, Infarctus sylvien malin, Middle cerebral artery, Brain Damage, Chronic, Female, Malignant middle cerebral artery infarction, Adult, medicine.medical_specialty, Hospital Departments, Rééducation, 03 medical and health sciences, Physical medicine and rehabilitation, craniectomy, medicine.artery, Craniectomie, medicine, Humans, Surgical Wound Infection, Retrospective Studies, Inpatients, business.industry, Retrospective cohort study, Recovery of Function, Length of Stay, Physical and Rehabilitation Medicine, medicine.disease, Surgery, malignant cerebral, business, 030217 neurology & neurosurgery
Abstract

Objectives To observe whether medical complications, the evolution of neurological disorders and dependence and/or the discharge destinations are different for patients treated by craniectomy for malignant cerebral infarction in the middle cerebral artery compared to patients treated medically for severe or malignant cerebral infarction in the same cerebral territory, during their hospitalization in a physical medicine and rehabilitation department. Patients and methods This retrospective study compared patients treated by craniectomy for malignant cerebral infarction in the middle cerebral artery and patients treated medically for severe or malignant cerebral infarction in the same cerebral territory. Patients were paired according to age, lesion side and hospitalization period. Results Twelve patients treated by craniectomy (age 43 ± 10.44) were paired with 12 patients treated medically (age 49 ± 7.66). The two groups were comparable in terms of general undesirable medical events. The medical events related to craniectomy are described. The evolution of patient deficiencies, the length of the hospital stay (194 ± 118.93 days vs 152 ± 94.64 days), the Functional Independence Measure at discharge (87 ± 21.28 vs 95 ± 22.19) and the number of direct home discharges (7 vs 9) did not significantly differ between groups. Discussion and conclusion No more medical problems were observed in the patients treated by craniectomy than in the patients treated medically, except for the medical events specifically related to craniectomy, which extended the hospital stay but had no major repercussions.

Published
2010

20. Exercise training effects on NOS1, RyR2 and beta3-adrenoceptor in diabetic rat heart: implications on cardiac function

Author

Le Douairon Lahaye, Solène, Malardé, Ludivine, Zguira, M. S., Rébillard, Amélie, Vincent, Serge, Sophie, V, Delamarche, Paul, Carré, F., Rannou-Bekono, Françoise, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Signalisation et Réponses aux Agents Infectieux et Chimiques (SeRAIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UR), and Auger, Clément

Subjects
[SDV] Life Sciences [q-bio], Exercise training, [SDV]Life Sciences [q-bio], diabetic rat heart, RyR2, cardiac function, beta3-adrenoceptor, NOS1
Published
2010

21. Effects of soccer training on anthropometric and physiological characteristics of elite youth soccer players

Author

Le Moal, Emmeran, Hammami, A., Nebigh, Ammar, Ben Abderrahmane, A., Belguith, Hatem, Ladham, T., Zouhal, Hassane, Crétual, Armel, Laboratoire de Physiologie et des Explorations Fonctionnelles [Tunisie], Faculté de Médecine Ibn Eljazzar, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
anthropometric, elite youth soccer players, soccer training, physiological characteristics
Published
2010

22. Evolution of anthropometric and performance characterictics of tunisian elite youth soccer players: a longitudinal study

Author

Hammami, Mohamed Ali, Nebigh, Ammar, Ben Abderrahmane, A., Le Moal, Emmeran, Tabka, Zouhair, Zouhal, Hassane, Laboratoire de Physiologie et des Explorations Fonctionnelles [Tunisie], Faculté de Médecine Ibn Eljazzar, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
soccer players, youth, anthropometric, performance characterictics, tunisian
Published
2010

23. Energy system contribution to olympic distances in flat water kayaking (500m and 1000m) in higly trained subjects

Author

Solène Le Douairon Lahaye, Guenole Minter, Romaric Herbez, Carlo Castagna, Abderraouf Ben Abderrahaman, Hassane Zouhal, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
Male, higly trained subjects, Anaerobic Threshold, [SDV]Life Sciences [q-bio], Physical Therapy, Sports Therapy and Rehabilitation, 030204 cardiovascular system & hematology, Athletic Performance, 500m, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Animal science, Oxygen Consumption, Humans, Orthopedics and Sports Medicine, Exercise physiology, Energy system, Exercise, olympic distances, Trained subjects, ComputingMilieux_MISCELLANEOUS, Mathematics, VO2 max, 030229 sport sciences, General Medicine, Oxygen deficit, Gas analyzer, 1000m, flat water kayaking, Physical Endurance, Energy Metabolism, Anaerobic exercise, Field conditions, Sports
Abstract

Olympic flat water kayaking races take place over a distance of 500 and 1,000 m. This study was designed to determine the aerobic and anaerobic contributions to 500- and 1,000-m races during flat water paddling in open water, using the accumulated oxygen deficit (AOD) method. Seven internationally ranked athletes, specialized in 500-m races and familiar with 1,000-m races, participated in this study (age: 21.86 ± 1.68 years, body mass: 78.54 ± 3.41 kg, height: 1.84 ± 0.03 m, body fat%: 10.14 ± 0.69%). All the participants performed 3 track-kayaking sessions. During the first session, the maximal oxygen uptake and maximal aerobic speed were determined using a portable gas analyzer and a global positioning system. During the successive testing sessions, paddlers performed in a randomized counterbalanced order a 500- and a 1,000-m race under field conditions (open water track kayaking). The 500-m AOD was significantly higher than the 1,000-m AOD (18.16 ± 4.88 vs. 9.34 ± 1.38 ml·kg(-1), p < 0.05). The aerobic contribution resulted in being higher during the 1,000 m compared with that in the 500-m condition (86.61 ± 1.86% vs. 78.30 ± 1.85%, respectively, p < 0.05). The results of this study showed that the 500- and 1,000-m races are 2 physiologically different kayaking events with a higher aerobic contribution in the 1,000 m. The training prescription for elite athletes should emphasize aerobic high-intensity training for the 1,000 m and anaerobic short-term training for the 500-m race.

Published
2010

24. Evolution of anthropometric caracteristics and physical fitness during a season of soccer in elite youth soccer players: effect of playing position

Author

Le Moal, Emmeran, Hammami, Mohamed Ali, Nebigh, Ammar, Ben Abderrahmane, A., Belguith, Hatem, Ladham, T., Crétual, Armel, Zouhal, Hassane, Laboratoire de Physiologie et des Explorations Fonctionnelles [Tunisie], Faculté de Médecine Ibn Eljazzar, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
soccer players, youth, anthropometric caracteristics, physical fitness, playing position
Published
2010

25. No effect of 7 weeks interval training program on plasma volume, hematocrit and hemoglobin responses to maximal exercise in adult male subjects

Author

Ben Abderrahmane, A., Thevenet, David, Prioux, Jacques, Mrizek, I., Ben Ounis, O., Chamari, K., Tabka, Zouhair, Zouhal, Hassane, Laboratoire brestois de mécanique et des systèmes (LBMS), École Nationale d'Ingénieurs de Brest (ENIB)-Université de Brest (UBO)-École Nationale Supérieure de Techniques Avancées Bretagne (ENSTA Bretagne), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Laboratoire de Physiologie et des Explorations Fonctionnelles [Tunisie], Faculté de Médecine Ibn Eljazzar, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
hemoglobin responses, maximal exercise, adult male subjects, hematocrit, training program, plasma volume
Published
2010

26. Exercise training potentiated the beneficial effect of insulin on cardiac function of type 1 diabetic rats

Author

Le Douairon Lahaye, Solène, Malardé, Ludivine, Rébillard, Amélie, Vincent, Sophie, Sophie, V, Delamarche, Arlette, Carré, F., Rannou-Bekono, Françoise, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Signalisation et Réponses aux Agents Infectieux et Chimiques (SeRAIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Auger, Clément, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Université de Rennes (UR)

Subjects
[SDV] Life Sciences [q-bio], insulin, type 1, [SDV]Life Sciences [q-bio], diabetic rats, cardiac function, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2010

27. De l'analyse de l'activité des défenseurs centraux lors de moments de transitions en football à l'ingénierie de dispositifs d'entraînement

Author

Gesbert, Vincent, Durny, Annick, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Auger, Clément, and École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
football, défenseurs centraux, dispositifs d'entraînement, analyse, ingénierie
Published
2010

28. Résistance au storytelling : l'ironie narrative science-fictionnelle

Author

Langlet, Irène, Espaces Humains et Interactions Culturelles (EHIC), Institut Sciences de l'Homme et de la Société (IR SHS UNILIM), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-Université Clermont Auvergne (UCA)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Auger, Clément, Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut Sciences de l'Homme et de la Société (IR SHS UNILIM), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Université Clermont Auvergne (UCA), and Langlet, Irène

Subjects
narration, [SHS.LITT] Humanities and Social Sciences/Literature, ironie, [SHS.LITT]Humanities and Social Sciences/Literature, storytelling, science-fiction, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2010

29. Combined effects of type 1 diabetes and exercise training on cardiac function: study of NOS1, RyR2 and β3-adrenoceptor

Author

Le Douairon Lahaye, Solène, Malardé, Ludivine, Zguira, M. S., Rébillard, Amélie, Vincent, Sophie, Sophie, V, Delamarche, Paul, Carré, F., Rannou-Bekono, Françoise, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Signalisation et Réponses aux Agents Infectieux et Chimiques (SeRAIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Auger, Clément, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Université de Rennes (UR)

Subjects
[SDV] Life Sciences [q-bio], type 1 diabetes, [SDV]Life Sciences [q-bio], RyR2, cardiac function, β3-adrenoceptor, exercise training, NOS1
Published
2010

30. Androgen Responses to Sprint Exercise in Young Men

Author

Derbré, Frédéric, Vincent, Serge, Botcazou, Maitel, Jacob, Christian, Delamarche, Paul, Delamarche, Arlette, Zouhal, Hassane, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Auger, Clément, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), and Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
Sprint Exercise, Young Men, ComputingMilieux_MISCELLANEOUS, Androgen
Abstract

International audience

Published
2010

31. Hypoleptinaemia in extreme body mass models: the case of international rugby players

Author

Christine Chappard, Claude-Laurent Benhamou, Stefan Breban, Chrystel Jaffre, Laboratoire d’Électrotechnique et d’Électronique de Puissance - ULR 2697 (L2EP), Centrale Lille-Haute Etude d'Ingénieurs-Université de Lille-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), Caractérisation du tissu osseux par imagerie : techniques et applications, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional d'Orléans (CHRO)-Université d'Orléans (UO), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Ecole Nationale Supérieure de Chimie de Rennes (ENSCR), Laboratoire d’Électrotechnique et d’Électronique de Puissance - EA 2697 (L2EP), Arts et Métiers Sciences et Technologies, Université d'Orléans (UO)-Centre Hospitalier Régional d'Orléans (CHR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Laboratoire Chimie des Nuisances et Génie de l'Environnement, Ecole Nationale Supérieure de Chimie de Rennes, Université d'Orléans (UO)-Centre Hospitalier Régional d'Orléans (CHRO)-Institut National de la Santé et de la Recherche Médicale (INSERM), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
Adult, Leptin, Male, medicine.medical_specialty, Adolescent, [SDV]Life Sciences [q-bio], medicine.medical_treatment, Osteocalcin, Football, 030209 endocrinology & metabolism, Physical Therapy, Sports Therapy and Rehabilitation, Hypoleptinaemia, Collagen Type I, Bone remodeling, Body Mass Index, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Bone Density, Internal medicine, medicine, Humans, Insulin, Orthopedics and Sports Medicine, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Leptin Deficiency, Adiponectin, biology, business.industry, [SDV] Life Sciences [q-bio], Endocrinology, Adipose Tissue, Athletes, Case-Control Studies, Lean body mass, biology.protein, rugby players, Bone Remodeling, business, Peptides, Body mass index
Abstract

Leptinaemia has been poorly studied in athlete populations with the consequences of athletic hypoleptinaemia yet to be examined. Our aim was to determine if systemic leptinaemia is influenced in high body mass athletes. We recruited 24 rugby players (21.5+/-4.7 years; 11.8+/-2.9h/week) and 26 controls (22.3+/-3.1 years; 1.9+/-1.4h/week). BMD (whole body (WB), limbs, lumbar spine and non-dominant femur) and body composition (WB Lean Mass (LM) and FM) were measured by Dual X-ray Absorptiometry. Circulating levels of serum leptin (ng/ml), adiponectin (microg/ml), insulin (ng/ml), osteocalcin (ng/ml) and CTx (ng/ml) were assessed by ELISA assays. BMD were significantly higher in rugby players vs controls, at all bone sites, yet after adjustments for body mass index. They had significantly higher LM and FM but no differences in %FM. They had significantly higher osteocalcin but lower CTx, insulin and leptin concentrations. Leptin levels were strongly correlated to %FM (r=0.85, p

Published
2010

32. Mechanisms of sensory effects of tacrolimus on the skin

Author

Pereira, U., Boulais, Nicholas, Lebonvallet, Nicolas, Pennec J., P., Dorange, G., Misery, Laurent, Laboratoire d'Anatomie Pathologique, Hôpital Morvan Brest-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Auger, Clément, and École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
sensory effects of tacrolimus
Published
2010

33. Continuous versus interval aerobic training in 8-11 year-old children

Author

Baquet, G., Gamelin, F.X., Mucci, P., Van Praagh, E., Berthoin, Serge, Thevenet, Delphine, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
8-11 year-old, children, aerobic training
Published
2010

34. Exercise and zoledronic acid on lipid profile and bone remodeling in ovariectomized rats : a paradoxical negative association ?

Author

Daniel Courteix, Gaël Y. Rochefort, Christelle Jaffré, Claude-Laurent Benhamou, E. Dolleans, Eric Lespessailles, Caractérisation du tissu osseux par imagerie : techniques et applications, Université d'Orléans (UO)-Centre Hospitalier Régional d'Orléans (CHRO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Ecole Nationale Supérieure de Chimie de Rennes (ENSCR), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional d'Orléans (CHRO)-Université d'Orléans (UO), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
endocrine system, medicine.medical_specialty, Clinical chemistry, Ovariectomy, 030209 endocrinology & metabolism, ovariectomized rats, Biochemistry, Bone resorption, Bone remodeling, 03 medical and health sciences, zoledronic acid, 0302 clinical medicine, Internal medicine, Physical Conditioning, Animal, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Medicine, Animals, Rats, Wistar, Exercise, ComputingMilieux_MISCELLANEOUS, bone remodeling, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, Bone Density Conservation Agents, Diphosphonates, business.industry, Tumor Necrosis Factor-alpha, Organic Chemistry, Imidazoles, Lipid metabolism, Cell Biology, Lipid Metabolism, Lipids, Rats, lipid profile, surgical procedures, operative, Zoledronic acid, Endocrinology, Ovariectomized rat, Female, business, Lipid profile, hormones, hormone substitutes, and hormone antagonists, Biomarkers, medicine.drug, Lipidology
Abstract

Exercise (EXE) and amino-bisphosphonates (BP) are both considered as useful strategies in the prevention of post-menopausal bone loss. Exercise reduces lipid levels, and BP may induce increase in high-density lipoprotein cholesterol (HDL-C). We hypothesized that combined effects of BP and exercise would produce a better improvement of lipid profile. We studied the specific and combined effects of zoledronic acid (Z) and EXE on lipid profile and bone remodeling in mature ovariectomized (OVX) rats. Six-month old female rats were randomly assigned to either a sham-ovx group (n = 12) or one of four OVX groups (n = 12): vehicle-treated sedentary (OVX); OVX + EXE (OVX-E, running on a treadmill for 12 weeks); OVX + Z (20 microg/kg, i.v.), (OVX-Z); OVX + Z+EXE (OVX-ZE). Total cholesterol (TC), HDL-C and bone remodeling markers were measured at baseline and at the end of the study. We demonstrated that both Z and EXE prevented the increase in bone resorption resulting from OVX, and individually improved the atherosclerotic risk index. Therapy with Z resulted in significant increase (39.00 +/- 0.03 vs. 53.6 +/- 0.01 mg/dl; +37.4%, P0.05) in serum concentration of HDL-C and a non significant decrease in TC (135.30 +/- 0.03 vs. 144.80 +/- 0.05 mg/dl; -5.8%) in the OVX-Z group compared to the OVX group. Post-menopausal women have elevated risk of CVD and bone resorption, hence, these data ultimately demonstrate (except for the elevated ratio in the combined group) that exercise and zoledronic acid are useful in minimizing the impact of these two processes in women and the combination of the two may be clinically relevant.

Published
2010

35. Assessment of child-specific aerobic fitness and anaerobic capacity by the use of the power-time relationships constants

Author

Benoit Borel, Serge Berthoin, Georges Baquet, Patrick Mucci, Delphine Thevenet, Erwan Leclair, Laboratoire d'étude de la motricité humaine - EA 3608 (LEMH), Université de Lille, Droit et Santé, Activité Physique, Muscle, Santé (EA4488), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Lille, Univ. Artois, Univ. Littoral Côte d’Opale, Laboratoire d'étude de la motricité humaine - EA 3608 [LEMH], Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS], Laboratoire Mouvement Sport Santé [M2S], Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
Adult, Male, medicine.medical_specialty, power-time relationships constants, Anaerobic Threshold, Physical Therapy, Sports Therapy and Rehabilitation, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Animal science, anaerobic capacity, medicine, Aerobic exercise, Humans, Orthopedics and Sports Medicine, Sexual Maturation, Exercise physiology, Low correlation, Child, Exercise, ComputingMilieux_MISCELLANEOUS, Mathematics, Age Factors, Exercise Test, Oxygen, Reproducibility of Results, child-specific aerobic fitness, VO2 max, 030229 sport sciences, Oxygen deficit, Pediatrics, Perinatology and Child Health, Physical therapy, Constant load, Anaerobic capacity, Anaerobic exercise
Abstract

This study first aimed to compare critical power (CP) and anaerobic work capacity (AWC), to laboratory standard evaluation methods such as maximal oxygen uptake (V̇O2max) and maximal accumulated oxygen deficit (MAOD). Secondly, this study compared child and adult CP and AWC values. Subjects performed a maximal graded test to determine V̇O2max and maximal aerobic power (MAP); and four constant load exercises. In children, CP (W.kg−1) was related to V̇O2max (ml.kg−1.min−1; r = .68; p = .004). AWC (J.kg−1) in children was related to MAOD (r = .58; p = .018). Children presented lower AWC (J.kg−1; p = .001) than adults, but similar CP (%MAP) values. CP (%MAP and W.kg−1) and AWC (J.kg−1) were significantly related to laboratory standard evaluation methods but low correlation indicated that they cannot be used interchangeably. CP (%MAP) was similar in children and adults, but AWC (J.kg−1) was significantly lower in children. These conclusions support existing knowledge related to child-adults characteristics.

Published
2010

36. Sodium channel NaV1.5 expression is enhanced in cultured adult rat skeletal muscle fibres

Author

Morel, J., Rannou, Francois, Talarmin, Hélène, Giroux-Metges, Marie-Agnès, Pennec J., P., Dorange, G., Gueret, G., Service de rééducation et de réadaptation de l'appareil locomoteur et des pathologies du rachis [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Auger, Clément, CHU Cochin [AP-HP]-Assistance publique - Hôpitaux de Paris (AP-HP), Laboratoire Mouvement Sport Santé ( M2S ), École normale supérieure - Cachan ( ENS Cachan ) -Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -Université de Brest ( UBO ) -Université de Rennes 2 ( UR2 ), and Université de Rennes ( UNIV-RENNES ) -Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
skeletal muscle fibres, expression, adult rat, Sodium channel NaV1.5, cultured
Published
2010

37. A new system for analyzing swim fin propulsion based on human kinematic data

Author

Paul Delamarche, Nicolas Bideau, Guillaume Nicolas, Benoit Bideau, Briac Colobert, Gaël Le Guerroue, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut de Recherche Mathématique de Rennes (IRMAR), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Rennes (ENS Rennes)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-AGROCAMPUS OUEST, Laboratoire Mouvement Sport Santé ( M2S ), École normale supérieure - Cachan ( ENS Cachan ) -Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -Université de Brest ( UBO ) -Université de Rennes 2 ( UR2 ), Université de Rennes ( UNIV-RENNES ) -Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut de Recherche Mathématique de Rennes ( IRMAR ), Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -AGROCAMPUS OUEST-École normale supérieure - Rennes ( ENS Rennes ) -Institut National de Recherche en Informatique et en Automatique ( Inria ) -Institut National des Sciences Appliquées ( INSA ) -Université de Rennes 2 ( UR2 ), Université de Rennes ( UNIV-RENNES ) -Centre National de la Recherche Scientifique ( CNRS ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École normale supérieure - Rennes (ENS Rennes)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), and Auger, Clément

Subjects
Test bench, Engineering, Fin, Biomedical Engineering, Biophysics, Kinematics, Propulsion, 03 medical and health sciences, symbols.namesake, 0302 clinical medicine, Humans, Orthopedics and Sports Medicine, human kinematic data, Swimming, Simulation, Mechanical energy, ComputingMilieux_MISCELLANEOUS, business.industry, Rehabilitation, Work (physics), Extremities, Body movement, 030229 sport sciences, Biomechanical Phenomena, swim fin propulsion, symbols, Strouhal number, business, human activities, 030217 neurology & neurosurgery, Marine engineering
Abstract

The use of swim fins has become popular in various water sport activities. While numerous models of swim fin with various innovative shapes have been subjectively designed, the exact influence of the fin characteristics on swimming performance is still much debated, and remains difficult to quantify. To date, the most common approach for evaluating swim fin propulsion is based on the study of "swimmer-fins" as a global system, where physiological and/or biomechanical responses are considered. However, reproducible swimming technique is difficult (or even impossible) to obtain on human body and may lead to discrepancies in data acquired between trials. In this study, we present and validate a new automat called HERMES which enables an evaluation of various swim fins during an adjustable, standardized and reproducible motion. This test bench reliably and accurately reproduces human fin-swimming motions, and gives resulting dynamic measurements at the ankle joint. Seven fins with various geometrical and mechanical characteristics were tested. For each swim fin, ankle force and hydromechanical efficiency (useful mechanical power output divided by mechanical power input delivered by the motors) were calculated. Efficiencies reported in our study were high (close to 70% for some swim fins) over a narrow range of Strouhal number (St) and peaks within the interval 0.2

Published
2010

38. Body mass index and quantitative osseous ultrasonography of the phalanges in Lebanese post-menarcheal adolescent girls

Author

El Hage, Roland, Jacob, C., Moussa, E., Benhamou, Claude-Laurent, Jaffre, Chrystel, Auger, Clément, Laboratoire Hippolyte Fizeau (FIZEAU), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Caractérisation du tissu osseux par imagerie : techniques et applications, Université d'Orléans (UO)-Centre Hospitalier Régional d'Orléans (CHRO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ecole Nationale Supérieure de Chimie de Rennes (ENSCR), Université Nice Sophia Antipolis (1965 - 2019) (UNS), and École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
quantitative osseous ultrasonography, Lebanese post-menarcheal adolescent girls, Body mass index
Published
2010

39. A comparison between ventilation and heart rate as an indicator of oxygen uptake during different intensities of exercice

Author

Gastinger, Steven, Sorel, A., Nicolas, Guillaume, Delamarche, Arlette, Prioux, Jacques, Laboratoire de Physiologie et de Biomécanique de l'Exercice Musculaire. UHB, Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Auger, Clément, and École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
oxygen uptake, heart rate, ventilatio, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2010

40. L'œuvre arthurienne de Rio et les réécritures de genre contemporaines

Author

Irène Langlet, Anne Besson, Auger, Clément, Espaces Humains et Interactions Culturelles (EHIC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut Sciences de l'Homme et de la Société (IR SHS UNILIM), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Université Clermont Auvergne (UCA), Institut Sciences de l'Homme et de la Société (IR SHS UNILIM), and Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-Université Clermont Auvergne (UCA)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])

Subjects
[SHS.LITT] Humanities and Social Sciences/Literature, Michel Rio, [SHS.LITT]Humanities and Social Sciences/Literature, cycle arthurien, littérature contemporaine, réécritures
Published
2010

41. Rôle de la combinaison de la restriction calorique et de l'entraînement physique individualisé dans la prise en charge de l'obésité infantile

Author

Ben Ounis, O., Elloumi, Mohamed, Amri, Mohammed, Zouhal, Hassane, Tabka, Zouhair, Lac, Gérard, Auger, Clément, Laboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-UFR Sciences et Techniques des Activités Physiques et Sportives - Clermont-Ferrand (UFR STAPS - UBP), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP), Laboratoire de Physiologie et des Explorations Fonctionnelles [Tunisie], Faculté de Médecine Ibn Eljazzar, Laboratoire de Physiologie de la Nutrition, Faculté des Sciences Mathématiques, Physiques et Naturelles de Tunis (FST), Université de Tunis El Manar (UTM)-Université de Tunis El Manar (UTM), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Laboratoire de Biologie des Activités Physiques et Sportives (BAPS), Université Blaise Pascal - Clermont-Ferrand 2 (UBP), UFR Sciences et Techniques des Activités Physiques et Sportives - Clermont-Ferrand (UFR STAPS - UBP), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), and Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
obésité infantile, restriction calorique, entraînement physique individualisé, ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2010

42. system contribution to 400m flat and 400m hurdles running in highly trained athletes

Author

Zouhal, Hassane, Jabbour, G., Moussa, E., Botcazou, Maitel, Ben Adberrahmane, R., Prioux, Jacques, Jacob, C., Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), INPT, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), and Auger, Clément

Subjects
400m hurdles, highly trained athletes, 400m flat
Published
2010

43. Analogie et coordination en comme

Author

Marianne Desmets, François Mouret, Laboratoire de Linguistique Formelle (LLF UMR7110), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes des littératures Anciennes et Modernes. UHB (CELAM), Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Structures Formelles du Langage (SFL), Université Paris 8 Vincennes-Saint-Denis (UP8)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Lumières (UPL), Modèles, Dynamiques, Corpus (MoDyCo), Université Paris Nanterre (UPN)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Auger, Clément, and Université Paris 8 Vincennes-Saint-Denis (UP8)-Centre National de la Recherche Scientifique (CNRS)- Université Paris Lumières, Académie de Créteil, Campus Condorcet (UPLUM)

Subjects
060201 languages & linguistics, coordination, Analogie, [SHS.LITT]Humanities and Social Sciences/Literature, syntaxe, Philosophy, ACL, comme, French, de même que, 06 humanities and the arts, ainsi que, 060202 literary studies, [SHS.LANGUE] Humanities and Social Sciences/Linguistics, connecteurs, language.human_language, [SHS.LITT] Humanities and Social Sciences/Literature, comparaison, 0602 languages and literature, language, sémantique, [SHS.LANGUE]Humanities and Social Sciences/Linguistics, Humanities, Pragmatic function, ComputingMilieux_MISCELLANEOUS
Abstract

Le mot comme peut, lorsqu’il relie deux SN sujets, donner lieu à deux types d’accord : dans le cas d’une comparative elliptique dite « comparative d’analogie » ajout à la phrase, le verbe s’accorde avec le premier sujet réalisé et la séquence introduite par comme est prosodiquement « incidente ». Dans le cas d’un accord avec la construction SN comme SN dans son ensemble, la séquence est au contraire prosodiquement intégrée ; nous montrons qu’il s’agit là d’une structure coordonnée, avec une recatégorisation de l’adverbe comme en conjonction. Sur le plan interprétatif, en revanche, la construction coordonnée conserve certains traits de l’ajout comparatif. La différence se situe au niveau pragmatique : la contribution de la comparative d’analogie relève du commentaire en arrière plan alors que la contribution de la coordination appartient au contenu principal asserté. Ce double fonctionnement ne s’étend pas tel quel aux autres formes similatives du français (ainsi que, de même que). When it links two NP subjects, the French word comme may trigger two kinds of agreement: in the case of an elliptic comparative clause, called « comparative of analogy », which is an adjunct to the main clause, the verb agrees with the first subject, and the comme-phrase is prosodically incidental. In the case of an agreement with the whole NP comme NP construction, the comme-phrase is prosodically integrated; we show that it must be analyzed as a coordinate construction, with the adverb comme recategorized as a conjunction. At the semantic level, however, the coordinate construction still displays some comparative features. The difference takes place in pragmatics: the semantic contribution of the comparative of analogy construction is understood as a background comment (i.e., it is a parenthetical phrase), whereas the contribution of the coordination construction belongs to the content of the main assertion. This double behavior does not extend straightforwardly to the other similative forms available in French (ainsi que, de même que).

Published
2010

44. Mechanisms of the sensory effects of tacrolimus on the skin

Author

Pereira, U., Boulais, Nicholas, Lebonvallet, Nicolas, Pennec, Jean-Pierre, Dorange, G., Misery, Laurent, Auger, Clément, Laboratoire d'Anatomie Pathologique, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-Hôpital Morvan Brest, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Facteurs nerveux et structuration tissulaire, Université de Brest (UBO), Laboratoire sur les interactions Epithéliums Neurones (LIEN), Hôpital Morvan Brest-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), and École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
[SDV]Life Sciences [q-bio], tacrolimus, ComputingMilieux_MISCELLANEOUS, sensory effects
Abstract

International audience

Published
2010

45. Infuence of Swimming Start Styles on Biomechanics and Angular Momentum

Author

Vantorre, J., Seifert, L., Bideau, Benoit, Nicolas, Guillaume, Fernandes, J., Vilas-Boas, J.-P., Chollet, Didier, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Auger, Clément, and École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
Biomechanic, Swimming Start Styles, Angular Momentum
Published
2010

46. Post operative self-report of pain in children : interscale agreement, response to anagesic, and preference for a faces scale ans a visual analogue scalePost operative self-report of pain in children : interscale agreement, response to anagesic, and preference for a faces scale ans a visual analogue scale

Author

de Tovar, C., von Baeyer, C.L., Wood, C., Alibeu, J.P., Houfani, M., Arvieux, C.C., Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
scale, children, pain
Published
2010

47. Estimates of ventilation from measurements of rib cage and abdominal distances : a portable device

Author

Guillaume Nicolas, Arlette Gratas-Delamarche, Anthony Sorel, Hamid Sefati, Jacques Prioux, Steven Gastinger, Auger, Clément, Laboratoire de Physiologie et de Biomécanique de l'Exercice Musculaire. UHB, Université de Rennes 2 (UR2), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), and Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
Adult, Male, Physiology, Daily life activities, Monitoring, Ambulatory, Ribs, 030204 cardiovascular system & hematology, Motor Activity, Sensitivity and Specificity, Standing Positions, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Physiology (medical), Humans, Orthopedics and Sports Medicine, Pooled data, New device, Respiratory system, ComputingMilieux_MISCELLANEOUS, Physics, Anthropometry, ventilation, Abdominal Wall, Public Health, Environmental and Occupational Health, Reproducibility of Results, 030229 sport sciences, General Medicine, Human physiology, Equipment Design, rib cage, abdominal distances, Equipment Failure Analysis, Crystallography, Spirometry, Female, Pulmonary Ventilation
Abstract

To validate a new device designed to measure ventilation \( \left( {\dot{V}_{\text{E}} } \right), \) tidal volume (VT), inspiratory time (TI), and expiratory time (TE) during daily life activities. The anteroposterior displacement of the rib cage and abdomen and the axial displacements of the chest wall and the spine were measured using two pairs of magnetometers. \( \dot{V}_{\text{E}} \) was estimated from these four signals, and was simultaneously measured using a spirometer. A total of 707, 732, and 1,138 breaths were analyzed in sitting, standing, and exercise conditions, respectively. We compared \( \dot{V}_{\text{E}} \), VT, TI, and, TE measured by magnetometers (\( \dot{V}_{{{\text{E}}\;{\text{mag}}}} \), VT mag, TI mag, and TE mag) with \( \dot{V}_{\text{E}} \), VT, TI, and TE measured by a spirometer (\( \dot{V}_{{{\text{E}}\;{\text{spiro}}}} \), VT spiro, TI spiro, and TE spiro, respectively). For pooled data \( \dot{V}_{{{\text{E}}\;{\text{mag}}}} \), VT mag, TI mag, and TE mag were significantly correlated (p < 0.001) with \( \dot{V}_{{{\text{E}}\;{\text{spiro}}}} \), VT spiro, TI spiro, and TE spiro in sitting and standing positions and during the walking exercise. The mean differences, between \( \dot{V}_{{{\text{E}}\;{\text{mag}}}} \), and \( \dot{V}_{{{\text{E}}\;{\text{spiro}}}} \) for the group, were 10.44, 10.74, and 12.06% in sitting, standing, and exercise conditions, respectively. These results demonstrate the capacity of this new device to measure \( \dot{V}_{\text{E}} \) with reasonable accuracy in sitting, standing, and exercise conditions.

Published
2010

48. A comparison between ventilation and heart rate as indicator of oxygen uptake during different intensities of exercise

Author

Jacques Prioux, Arlette Gratas-Delamarche, Guillaume Nicolas, Anthony Sorel, Steven Gastinger, Laboratoire de Physiologie et de Biomécanique de l'Exercice Musculaire. UHB, Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Auger, Clément

Subjects
lcsh:Sports, exercise, non-steady state activities, musculoskeletal, neural, and ocular physiology, ventilation, light to moderate intensities, steady state activities, lcsh:GV557-1198.995, oxygen uptake, Physical activities, heart rate, lcsh:Sports medicine, lcsh:RC1200-1245, human activities, circulatory and respiratory physiology, Research Article
Abstract

The aim of this study is to compare the relation between ventilation (VE) and oxygen uptake (VO2) [VO2=ƒ(VE)] and between heart rate (HR) and VO2 [VO2=ƒ(HR)]. Each one of the subjects performed three types of activities of different intensities (walking without load, walking with load and intermittent work). VO2, VE, and HR were measured continuously by using indirect calorimetry and an electrocardiogram. Linear regressions and coefficients of determination (r(2)) were calculated to compare the relation VO2 =ƒ(VE) and VO2 =ƒ(HR) for two different regroupings: by session duration (r(2) session) and by subject (r(2) subject). Results showed that r(2) session of the relation VO2 =ƒ(VE) were significantly higher than those of the relation VO2 =ƒ(HR) for steady state activities (walking with or without load during 3 or 6 min, p0.01) and for activities without oxygen consumption steady state (walking with or without load during 1 min, p0.01 and intermittent work, p0.05). VE is more strongly correlated with VO2 than with HR. This is a very promising approach to develop a new method to estimate energy expenditure. Key pointsVentilation is more strongly correlated with oxygen uptake than heart rate during physical activities of different intensities.This study shows the interest to looking for ventilation to estimate energy expenditure.This study is a promising approach to develop a new method to estimate energy expenditureAn interesting perspective could be to develop a light and portable device to measure ventilation based on the coupling of four magnetometers.

Published
2010

49. Anaerobic and aerobic energy system contribution to 400 m flat and 400 m hurdles track running

Author

Zouhal, Hassane, Jabbour, G., Jacob, Christian, Duvigneau, D., Botcazou, Maitel, Ben Abderrahmane, A., Prioux, Jacques, Moussa, E., Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), INPT, Auger, Clément, École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut National Polytechnique (Toulouse) (Toulouse INP), and Université de Toulouse (UT)

Subjects
Anaerobic, aerobic energy system, 400 m hurdles, ComputingMilieux_MISCELLANEOUS, 400 m flat
Abstract

International audience

Published
2010

50. Activation of MAP kinase signaling pathway in the mussel Mytilus galloprovincialis as biomarker of environmental pollution

Author

W. E. G. Müller, Bojan Hamer, Germaine Dorange, Amélie Châtel, Heinz-Christoph Schröder, Hélène Talarmin, Auger, Clément, Laboratoire Mouvement Sport Santé (M2S), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes (UR)-Université de Brest (UBO)-Université de Rennes 2 (UR2)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École normale supérieure - Cachan (ENS Cachan)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Rennes 2 (UR2), and Université de Rennes (UNIV-RENNES)-Université de Brest (UBO)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
MAPK/ERK pathway, mussel Mytilus galloprovincialis, MAP Kinase Kinase 4, MAP Kinase Signaling System, Health, Toxicology and Mutagenesis, p38 mitogen-activated protein kinases, Environmental pollution, Enzyme-Linked Immunosorbent Assay, pollution, biomarker, MAP kinase, mussel, Mytilus galloprovincialis, tributyltin, diesel oil, hydrogen peroxide, 010501 environmental sciences, Aquatic Science, 01 natural sciences, p38 Mitogen-Activated Protein Kinases, 03 medical and health sciences, chemistry.chemical_compound, Animals, 14. Life underwater, Extracellular Signal-Regulated MAP Kinases, 030304 developmental biology, 0105 earth and related environmental sciences, Mytilus, 0303 health sciences, biology, Kinase, Mussel, Hydrogen Peroxide, biology.organism_classification, Cell biology, Enzyme Activation, chemistry, 13. Climate action, Environmental chemistry, Mitogen-activated protein kinase, Tributyltin, biology.protein, Mitogen-Activated Protein Kinases, Trialkyltin Compounds, environmental pollution, Biomarkers, Gasoline, Water Pollutants, Chemical
Abstract

Stimulation of MAP kinase signal transduction pathway by various stressful stimuli was investigated in the marine bivalve Mytilus galloprovincialis. Analyses were performed in animals exposed in laboratory to selected pollutants and in mussels collected in winter and summer along the eastern Adriatic coast (Croatia). Effects of oxidative stress, induced by tributyltin, hydrogen peroxide and water soluble fraction of diesel fuel on the activation/phosphorylation of the three Mitogen-Activated Protein Kinases (MAPKs) p38, JNK and ERK using a newly developed ELISA procedure were evaluated. MAP kinase activation was analyzed 1 h after exposure of mussels to chemical agents, and after recovery periods of 6 and 24 h. Our results clearly indicated that pollutants generated different patterns of induction of the MAPK phosphorylation. Indeed, only pp38 and pJNK were activated with 11, 33 and 100 mmg/L TBT, reaching a maximum activation after 6 h in seawater following treatment of mussels with 11 mmg/L TBT. Treatment with 0.074 and 0.222 mM H2O2 enhanced activation of both p38 and ERK. These two kinases were activated after 1 h exposure, followed by a diminution after 6 h of recovery in seawater and a reactivation after 24 h. The levels of phoshorylated P38 and JNK were increased after mussel exposure with 7.5, 15 and 30 % of water soluble fraction of diesel oil. P38 was activated concentration dependently at 1 h exposure. Additionally, field study pointed out seasonal differences in MAP kinases activation as mussels collected during summer had a higher enzyme activation state than in winter, as well as sampling site differences which could be correlated to the industrial/tourism activity and environmental stresses (salinity). All the results converge towards MAP kinase signaling pathway being induced by various pollutants in M. galloprovincialis.This signaling cascade should be considered as a possible biomarker of environmental stress and pollution.

Published
2010

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