1. Correction for Frantz et al., Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe
- Author
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Ceiridwen J. Edwards, Anders Götherström, Benjamin S. Arbuckle, Linus Girdland-Flink, Domenico Fulgione, Ross Barnett, Michael J Richards, Katerina Trantalidou, Cristina Valdiosera, M. Thomas P. Gilbert, Joris Peters, Louis du Plessis, Jean-Denis Vigne, Joachim Burger, Dian Boric, Richard P. M. A. Crooijmans, Melinda A. Zeder, Erik Meijaard, Wolfram Schier, Panoraia Alexandri, Jörg Schibler, John Chapman, Adrian Balasescu, Greger Larson, Jörg Orschiedt, Anne Tresset, Simon Stoddart, Keith Dobney, Antonio Tagliacozzo, Thomas H. McGovern, Canan Çakirlar, Bea De Cupere, Caroline Malone, Laurent A. F. Frantz, Vesna Dimitrijević, Sepideh Maziar, Andrea Zeeb-Lanz, Cevdet Merih Erek, Adina Boroneant, Ash Erim-Ozdogan, Hendrik-Jan Megens, Azadeh Fatemeh Mohaseb, Hitomi Hongo, Marjan Mashkour, Amelie Scheu, Evan K. Irving-Pease, Michelle Alexander, David Orton, Richard Sabin, László Bartosiewicz, Nenad Tasić, François-Xavier Ricaut, Anastasia Papathanasiou, Darko Radmanovic, Liora Kolska Horwitz, Christina Geoerg, Clive Bonsall, Anna Linderholm, Peter Rowley-Conwy, Audrey T. Lin, Daniel Helmer, Daniel G. Bradley, Roger Matthews, Ron Pinhasi, Ninna Manaseryan, Shiva Sheikhi, Sophie Van Poucke, Lionel Gourichon, Mike J. Church, Kevin G. Daly, Valentin Dumitraşcu, Joséphine Lesur, Mihai Gligor, Martien A. M. Groenen, Alexander Yanevich, Vincent M. Battista, Cleia Detry, Max Price, Rose-Marie Arbogast, Holley Martlew, Allowen Evin, Elisabeth Stephan, Norbert Benecke, John R. Stewart, Ophélie Lebrasseur, Giedre Motuzaite Matuzeviciute, Gennady F. Baryshnikov, Lucia Sarti, Youri van den Hurk, James Haile, Mike Parker Pearson, Arkadiusz Marciniak, Victoria E. Mullin, Jose-Miguel Carreterow, Kurt J. Gron, Alexandros Triantafyllidis, Thomas Cucchi, Rebecca Miller, Jelena Bulatović, and Anton Ervynck
- Subjects
Gene Flow ,Multidisciplinary ,Swine ,Library science ,Skin Pigmentation ,Biological Sciences ,Corrections ,DNA, Mitochondrial ,Domestication ,Europe ,Middle East ,Anthropology ,evolution ,Animals ,Neolithic ,DNA, Ancient ,History, Ancient ,Phylogeny - Abstract
Significance Archaeological evidence indicates that domestic pigs arrived in Europe, alongside farmers from the Near East ∼8,500 y ago, yet mitochondrial genomes of modern European pigs are derived from European wild boars. To address this conundrum, we obtained mitochondrial and nuclear data from modern and ancient Near Eastern and European pigs. Our analyses indicate that, aside from a coat color gene, most Near Eastern ancestry in the genomes of European domestic pigs disappeared over 3,000 y as a result of interbreeding with local wild boars. This implies that pigs were not domesticated independently in Europe, yet the first 2,500 y of human-mediated selection applied by Near Eastern Neolithic farmers played little role in the development of modern European pigs., Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in the Near East, and mitochondrial DNA (mtDNA) suggests that pigs arrived in Europe alongside farmers ∼8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local European wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hypotheses, we obtained mtDNA sequences from 2,099 modern and ancient pig samples and 63 nuclear ancient genomes from Near Eastern and European pigs. Our analyses revealed that European domestic pigs dating from 7,100 to 6,000 y BP possessed both Near Eastern and European nuclear ancestry, while later pigs possessed no more than 4% Near Eastern ancestry, indicating that gene flow from European wild boars resulted in a near-complete disappearance of Near East ancestry. In addition, we demonstrate that a variant at a locus encoding black coat color likely originated in the Near East and persisted in European pigs. Altogether, our results indicate that while pigs were not independently domesticated in Europe, the vast majority of human-mediated selection over the past 5,000 y focused on the genomic fraction derived from the European wild boars, and not on the fraction that was selected by early Neolithic farmers over the first 2,500 y of the domestication process.
- Published
- 2020