1. Rectal cancer in old age –is it appropriately managed? Evidence from population-based analysis of routine data across the English national health service
- Author
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Birch, RJ, Taylor, JC, Downing, A, Spencer, K, Finan, PJ, Audisio, RA, Carrigan, CM, Selby, PJ, and Morris, EJA
- Subjects
Male ,Frail Elderly ,Comorbidity ,Psychological Distress ,Article ,State Medicine ,Postoperative Complications ,Age ,Humans ,Mass Screening ,Patient Reported Outcome Measures ,Geriatric Assessment ,Digestive System Surgical Procedures ,Colorectal ,Early Detection of Cancer ,Neoplasm Staging ,Retrospective Studies ,Cancer ,Aged ,Aged, 80 and over ,Proctectomy ,Radiotherapy ,Frailty ,Rectal Neoplasms ,Age Factors ,Rectum ,Chemoradiotherapy ,Neoadjuvant Therapy ,Survival Rate ,Logistic Models ,England ,Female ,Rectal ,Inequalities - Abstract
Background: There is significant debate as to where to draw the line between undertreating older rectal cancer patients and minimising treatment risks. This study sought to examine the use of radical rectal cancer treatments and associated outcomes in relation to age across the English NHS. Methods: Patient, tumour and treatment characteristics for all patients diagnosed with a first primary rectal cancer in England between 1st April 2009 and 31st December 2014 were obtained from the CORECT-R data repository. Descriptive analyses and adjusted logistic regression models were undertaken to examine any association between age and the use of major resection and post-surgical outcomes. Funnel plots were used to show variation in adjusted rates of major resection. Results: The proportion of patients who underwent a major surgical resection fell from 66.5% to 31.7%, amongst those aged
- Published
- 2019