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239 results on '"Aubry, Jean Francois"'

1. ITRUSST Consensus on Standardised Reporting for Transcranial Ultrasound Stimulation

Author

Martin, Eleanor, Aubry, Jean-François, Schafer, Mark, Verhagen, Lennart, Treeby, Bradley, and Pauly, Kim Butts

Subjects
Physics - Medical Physics, Physics - Biological Physics
Abstract

As transcranial ultrasound stimulation (TUS) advances as a precise, non-invasive neuromodulatory method, there is a need for consistent reporting standards to enable comparison and reproducibility across studies. To this end, the International Transcranial Ultrasonic Stimulation Safety and Standards Consortium (ITRUSST) formed a subcommittee of experts across several domains to review and suggest standardised reporting parameters for low intensity TUS, resulting in the guide presented here. The scope of the guide is limited to reporting the ultrasound aspects of a study. The guide and supplementary material provide a simple checklist covering the reporting of: (1) the transducer and drive system, (2) the drive system settings, (3) the free field acoustic parameters, (4) the pulse timing parameters, (5) \emph{in situ} estimates of exposure parameters in the brain, and (6) intensity parameters. Detailed explanations for each of the parameters, including discussions on assumptions, measurements, and calculations, are also provided., Comment: 23 pages, 4 figures, 4 tables, stand alone checklist

Published
2024

2. ITRUSST Consensus on Biophysical Safety for Transcranial Ultrasonic Stimulation

Author

Aubry, Jean-Francois, Attali, David, Schafer, Mark, Fouragnan, Elsa, Caskey, Charles, Chen, Robert, Darmani, Ghazaleh, Bubrick, Ellen J., Sallet, Jérôme, Butler, Christopher, Stagg, Charlotte, Klein-Flügge, Miriam, Yoo, Seung-Schik, Treeby, Brad, Verhagen, Lennart, and Pauly, Kim Butts

Subjects
Physics - Biological Physics, Physics - Medical Physics
Abstract

Transcranial ultrasonic stimulation (TUS) is an emerging technology for non-invasive brain stimulation. In a series of meetings, the International Consortium for Transcranial Ultrasonic Stimulation Safety and Standards (ITRUSST) has established expert consensus on considerations for the biophysical safety of TUS, drawing upon the relevant diagnostic ultrasound literature and regulations. This report reflects a consensus expert opinion and can inform but not replace regulatory guidelines or official international standards. Their establishment by international and national commissions will follow expert consensus. Similarly, this consensus will inform but not replace ethical evaluation, which will consider aspects beyond biophysical safety relevant to burden, risk, and benefit, such as physiological effects and disease-specific interactions. Here, we assume the application of TUS to persons who are not at risk for thermal or mechanical damage, and without ultrasound contrast agents. In this context, we present a concise yet comprehensive set of levels for a nonsignificant risk of TUS application. For mechanical effects, it is safe if the mechanical index (MI) or the mechanical index for transcranial application (MItc) does not exceed 1.9. For thermal effects, it is safe if any of the following three levels are met: a temperature rise less than 2 C, a thermal dose less than 0.25 CEM43, or specific values of the thermal index (TI) for a given exposure time. We review literature relevant to our considerations and discuss limitations and future developments of our approach., Comment: ITRUSST consensus, 15 pages, 1 table, 1 figure

Published
2023

3. Benchmark problems for transcranial ultrasound simulation: Intercomparison of compressional wave models

Author

Aubry, Jean-Francois, Bates, Oscar, Boehm, Christian, Pauly, Kim Butts, Christensen, Douglas, Cueto, Carlos, Gelat, Pierre, Guasch, Lluis, Jaros, Jiri, Jing, Yun, Jones, Rebecca, Li, Ningrui, Marty, Patrick, Montanaro, Hazael, Neufeld, Esra, Pichardo, Samuel, Pinton, Gianmarco, Pulkkinen, Aki, Stanziola, Antonio, Thielscher, Axel, Treeby, Bradley, and Wout, Elwin van 't

Subjects
Physics - Computational Physics
Abstract

Computational models of acoustic wave propagation are frequently used in transcranial ultrasound therapy, for example, to calculate the intracranial pressure field or to calculate phase delays to correct for skull distortions. To allow intercomparison between the different modeling tools and techniques used by the community, an international working group was convened to formulate a set of numerical benchmarks. Here, these benchmarks are presented, along with intercomparison results. Nine different benchmarks of increasing geometric complexity are defined. These include a single-layer planar bone immersed in water, a multi-layer bone, and a whole skull. Two transducer configurations are considered (a focused bowl and a plane piston), giving a total of 18 permutations of the benchmarks. Eleven different modeling tools are used to compute the benchmark results. The models span a wide range of numerical techniques, including the finite-difference time-domain method, angular-spectrum method, pseudospectral method, boundary-element method, and spectral-element method. Good agreement is found between the models, particularly for the position, size, and magnitude of the acoustic focus within the skull. When comparing results for each model with every other model in a cross comparison, the median values for each benchmark for the difference in focal pressure and position are less than 10\% and 1 mm, respectively. The benchmark definitions, model results, and intercomparison codes are freely available to facilitate further comparisons., Comment: 18 pages, 7 figures

Published
2022
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4. Sustained reduction of essential tremor with low-power non-thermal transcranial focused ultrasound stimulations in humans

Author

Bancel, Thomas, Béranger, Benoît, Daniel, Maxime, Didier, Mélanie, Santin, Mathieu, Rachmilevitch, Itay, Shapira, Yeruham, Tanter, Mickael, Bardinet, Eric, Fernandez Vidal, Sara, Attali, David, Galléa, Cécile, Dizeux, Alexandre, Vidailhet, Marie, Lehéricy, Stéphane, Grabli, David, Pyatigorskaya, Nadya, Karachi, Carine, Hainque, Elodie, and Aubry, Jean-François

Published
2024
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7. Three-layer model with absorption for conservative estimation of the maximum acoustic transmission coefficient through the human skull for transcranial ultrasound stimulation

Author

Attali, David, Tiennot, Thomas, Schafer, Mark, Fouragnan, Elsa, Sallet, Jérôme, Caskey, Charles F, Chen, Robert, Darmani, Ghazaleh, Bubrick, Ellen J., Butler, Christopher, Stagg, Charlotte J, Klein-Flügge, Miriam, Verhagen, Lennart, Yoo, Seung-Schik, Pauly, Kim Butts, and Aubry, Jean-Francois

Published
2023
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9. Ultra-short time-echo based ray tracing for transcranial focused ultrasound aberration correction in human calvaria

Author

Manuel, Thomas J, primary, Bancel, Thomas, additional, Tiennot, Thomas, additional, Didier, Mélanie, additional, Santin, Mathieu, additional, Daniel, Maxime, additional, Attali, David, additional, Tanter, Mickael, additional, Lehéricy, Stéphane, additional, Pyatigorskaya, Nadya, additional, and Aubry, Jean-Francois, additional

Published
2024
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13. Combining brain perturbation and neuroimaging in non-human primates

Author

Klink, P. Christiaan, Aubry, Jean-François, Ferrera, Vincent P., Fox, Andrew S., Froudist-Walsh, Sean, Jarraya, Béchir, Konofagou, Elisa E., Krauzlis, Richard J., Messinger, Adam, Mitchell, Anna S., Ortiz-Rios, Michael, Oya, Hiroyuki, Roberts, Angela C., Roe, Anna Wang, Rushworth, Matthew F.S., Sallet, Jérôme, Schmid, Michael Christoph, Schroeder, Charles E., Tasserie, Jordy, Tsao, Doris Y., Uhrig, Lynn, Vanduffel, Wim, Wilke, Melanie, Kagan, Igor, and Petkov, Christopher I.

Published
2021
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17. Non-ablative disease-modifying effects of magnetic resonance-guided focused ultrasound in neuromelanin-producing parkinsonian rodents

Author

Compte, Joan, primary, Tible, Marion, additional, Cuadros, Thais, additional, Romero-Jimenez, Jordi, additional, Laguna, Ariadna, additional, Aubry, Jean-Francois, additional, Dumont, Erik, additional, Constans, Charlotte, additional, Tiennot, Thomas, additional, Santin, Mathieu D, additional, Lehericy, Stephane, additional, and Vila, Miquel, additional

Published
2023
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18. Ultrasound therapy

Author

ter Haar, Gail, primary, Aubry, Jean Francois, additional, Gruell, Holger, additional, and Lafon, Cyril, additional

Published
2020
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25. Benchmark problems for transcranial ultrasound simulation: Intercomparison of compressional wave models

Author

Aubry, Jean-Francois, primary, Bates, Oscar, additional, Boehm, Christian, additional, Butts Pauly, Kim, additional, Christensen, Douglas, additional, Cueto, Carlos, additional, Gélat, Pierre, additional, Guasch, Lluis, additional, Jaros, Jiri, additional, Jing, Yun, additional, Jones, Rebecca, additional, Li, Ningrui, additional, Marty, Patrick, additional, Montanaro, Hazael, additional, Neufeld, Esra, additional, Pichardo, Samuel, additional, Pinton, Gianmarco, additional, Pulkkinen, Aki, additional, Stanziola, Antonio, additional, Thielscher, Axel, additional, Treeby, Bradley, additional, and van 't Wout, Elwin, additional

Published
2022
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48. Spatiotemporal coding in complex media for optimum beamforming: The iterative time-reversal approach

Author

Montaldo, Gabriel, Aubry, Jean-Francois, Tanter, Mickael, and Fink, Mathias

Subjects
Pulse code modulation -- Research, Signal processing -- Methods, Digital signal processor, Business, Electronics, Electronics and electrical industries
Abstract

An iterative time-reversal method capable of taking into account all the heterogeneities of the medium, concerning density, speed of sound, and absorption variations is proposed. The iterative focusing process that converges toward a spatio-temporal inverse filter focusing, the first step of the process that is time-reversal focusing on the targeted point is shown.

Published
2005

50. Fluoroscopy-Guided High-Intensity Focused Ultrasound Neurotomy of the Lumbar Zygapophyseal Joints: A Clinical Pilot Study.

Author

Perez, Jordi, Gofeld, Michael, Leblang, Suzanne, Hananel, Arik, Aginsky, Ron, Chen, Johnny, Aubry, Jean-Francois, and Shir, Yoram

Subjects
LUMBAR pain, CHRONIC pain, PILOT projects, DENERVATION, CLINICAL trials, PAIN measurement, PAIN, RADIO frequency therapy, CATHETER ablation, SURGICAL complications, FLUOROSCOPY, MORPHINE, ZYGAPOPHYSEAL joint, QUESTIONNAIRES, BRIEF Pain Inventory, DESCRIPTIVE statistics, LUMBAR vertebrae, NEUROLOGIC examination
Abstract

Objective To investigate the safety and feasibility of a fluoroscopy-guided, high-intensity focused ultrasound system for zygapophyseal joint denervation as a treatment for chronic low back pain. Methods The clinical pilot study was performed on 10 participants diagnosed with lumbar zygapophyseal joint syndrome. Each participant had a documented positive response to a diagnostic block or a previous, clinically beneficial radiofrequency ablation. For a descriptive study, the primary outcome was the safety question. All device- or procedure-related adverse events were collected. Secondary outcome variables included the average numeric rating scale for pain, the Roland-Morris Disability Questionnaire, the Brief Pain Inventory, the Patient Global Impression of Change, the morphine equivalent dose, and the finding of the neurological examination. Results All participants tolerated the procedure well with no significant device- or procedure-related adverse events; there was one episode of transient pain during the procedure. The average numeric rating scale score for pain decreased from 6.2 at baseline to 2.1 (n = 10) after 1 month, 4.9 (n = 9) after 3 months, 3.0 (n = 8) after 6 months, and 3.0 (n = 6) after 12 months. The ratio of participants who were considered a treatment success was 90% at 1 month, 50% at 3 months, 60% at 6 months, and 40% at 12 months. Conclusions The first clinical pilot study using a noninvasive, fluoroscopy-guided, high-intensity focused ultrasound lumbar zygapophyseal neurotomy resulted in no significant device- or procedure-related adverse events and achieved clinical success comparable with that of routine radiofrequency ablation. [ABSTRACT FROM AUTHOR]

Published
2022
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