40 results on '"Au, Teresa"'
Search Results
2. Self-Help Plus for refugees and asylum seekers: an individual participant data meta-analysis
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Karyotaki, Eirini, primary, Sijbrandij, Marit, additional, Purgato, Marianna, additional, Acarturk, Ceren, additional, Lakin, Daniel, additional, Bailey, Della, additional, Peckham, Emily, additional, Uygun, Ersin, additional, Tedeschi, Federico, additional, Wancata, Johannes, additional, Augustinavicius, Jura, additional, Carswell, Kenneth, additional, Välimäki, Maritta, additional, van Ommeren, Mark, additional, Koesters, Markus, additional, Popa, Mariana, additional, Leku, Marx Ronald, additional, Anttila, Minna, additional, Churchill, Rachel, additional, White, Ross G, additional, Al-Hashimi, Sarah, additional, Lantta, Tella, additional, Au, Teresa, additional, Klein, Thomas, additional, Tol, Wietse A, additional, Cuijpers, Pim, additional, and Barbui, Corrado, additional
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- 2023
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3. Compassion-Based Therapy for Trauma-Related Shame and Posttraumatic Stress: Initial Evaluation Using a Multiple Baseline Design
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Au, Teresa M., Sauer-Zavala, Shannon, King, Matthew W., Petrocchi, Nicola, Barlow, David H., and Litz, Brett T.
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- 2017
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4. Risk factors for mental disorder development in asylum seekers and refugees resettled in Western Europe and Turkey: participant-level analysis of two large prevention studies
- Author
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Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), Barbui, Corrado; Tedeschi, Federico; Anttila, Minna; Au, Teresa; Baumgartner, Josef; Carswell, Ken; Churchill, Rachel; Cuijpers, Pim; Karyotaki, Eirini; Klein, Thomas; Koesters, Markus; Lantta, Tella; Nose, Michela; Ostuzzi, Giovanni; Pasquini, Massimo; Prina, Eleonora; Sijbrandij, Marit; Tarsitani, Lorenzo; Turrini, Giulia; Uygun, Ersin; Valimaki, Maritta; Walker, Lauren; Wancata, Johannes; White, Ross G.; Purgato, Marianna, College of Social Sciences and Humanities, Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), Barbui, Corrado; Tedeschi, Federico; Anttila, Minna; Au, Teresa; Baumgartner, Josef; Carswell, Ken; Churchill, Rachel; Cuijpers, Pim; Karyotaki, Eirini; Klein, Thomas; Koesters, Markus; Lantta, Tella; Nose, Michela; Ostuzzi, Giovanni; Pasquini, Massimo; Prina, Eleonora; Sijbrandij, Marit; Tarsitani, Lorenzo; Turrini, Giulia; Uygun, Ersin; Valimaki, Maritta; Walker, Lauren; Wancata, Johannes; White, Ross G.; Purgato, Marianna, College of Social Sciences and Humanities, and Department of Psychology
- Abstract
Background: In asylum seekers and refugees, the frequency of mental disorders, such as depression, anxiety and post-traumatic stress disorder, is higher than the general population, but there is a lack of data on risk factors for the development of mental disorders in this population. Aim: This study investigated the risk factors for mental disorder development in a large group of asylum seekers and refugees resettled in high- and middle-income settings. Methods: Participant-level data from two randomized prevention studies involving asylum seekers and refugees resettled in Western European countries and in Turkey were pooled. The two studies randomized participants with psychological distress, but without a diagnosis of mental disorder, to the Self-Help Plus psychological intervention or enhanced care as usual. At baseline, exposure to potentially traumatic events was measured using the Harvard Trauma Questionnaire-part I, while psychological distress and depressive symptoms were assessed with the General Health Questionnaire and the Patient Health Questionnaire. After 3 and 6 months of follow-up, the proportion of participants who developed a mental disorder was calculated using the Mini International Neuropsychiatric Interview. Results: A total of 1,101 participants were included in the analysis. At 3- and 6-month follow-up the observed frequency of mental disorders was 13.51% (115/851) and 24.30% (207/852), respectively, while the frequency estimates after missing data imputation were 13.95% and 23.78%, respectively. After controlling for confounders, logistic regression analysis showed that participants with a lower education level (p = .034), a shorter duration of journey (p = .057) and arriving from countries with war-related contexts (p = .017), were more at risk of developing mental disorders. Psychological distress (p = .004), depression (p = .001) and exposure to potentially traumatic events (p = .020) were predictors of mental disorder development. Concl, European Union (EU); Horizon 2020; European Commission (EC); RE-DEFINE: Refugee Emergency: DEFining and Implementing Novel Evidence-based psychosocial interventions
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- 2023
5. Risk factors for mental disorder development in asylum seekers and refugees resettled in Western Europe and Turkey: Participant-level analysis of two large prevention studies
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Barbui, Corrado, Tedeschi, Federico, Acarturk, Ceren, Anttila, Minna, Au, Teresa, Baumgartner, Josef, Carswell, Ken, Churchill, Rachel, Cuijpers, Pim, Karyotaki, Eirini, Klein, Thomas, Koesters, Markus, Lantta, Tella, Nosè, Michela, Ostuzzi, Giovanni, Pasquini, Massimo, Prina, Eleonora, Sijbrandij, Marit, Tarsitani, Lorenzo, Turrini, Giulia, Uygun, Ersin, Välimäki, Maritta, Walker, Lauren, Wancata, Johannes, White, Ross G., Purgato, Marianna, Barbui, Corrado, Tedeschi, Federico, Acarturk, Ceren, Anttila, Minna, Au, Teresa, Baumgartner, Josef, Carswell, Ken, Churchill, Rachel, Cuijpers, Pim, Karyotaki, Eirini, Klein, Thomas, Koesters, Markus, Lantta, Tella, Nosè, Michela, Ostuzzi, Giovanni, Pasquini, Massimo, Prina, Eleonora, Sijbrandij, Marit, Tarsitani, Lorenzo, Turrini, Giulia, Uygun, Ersin, Välimäki, Maritta, Walker, Lauren, Wancata, Johannes, White, Ross G., and Purgato, Marianna
- Abstract
Background: In asylum seekers and refugees, the frequency of mental disorders, such as depression, anxiety and post-traumatic stress disorder, is higher than the general population, but there is a lack of data on risk factors for the development of mental disorders in this population. Aim: This study investigated the risk factors for mental disorder development in a large group of asylum seekers and refugees resettled in high- and middle-income settings. Methods: Participant-level data from two randomized prevention studies involving asylum seekers and refugees resettled in Western European countries and in Turkey were pooled. The two studies randomized participants with psychological distress, but without a diagnosis of mental disorder, to the Self-Help Plus psychological intervention or enhanced care as usual. At baseline, exposure to potentially traumatic events was measured using the Harvard Trauma Questionnaire-part I, while psychological distress and depressive symptoms were assessed with the General Health Questionnaire and the Patient Health Questionnaire. After 3 and 6 months of follow-up, the proportion of participants who developed a mental disorder was calculated using the Mini International Neuropsychiatric Interview. Results: A total of 1,101 participants were included in the analysis. At 3- and 6-month follow-up the observed frequency of mental disorders was 13.51% (115/851) and 24.30% (207/852), respectively, while the frequency estimates after missing data imputation were 13.95% and 23.78%, respectively. After controlling for confounders, logistic regression analysis showed that participants with a lower education level (p =.034), a shorter duration of journey (p =.057) and arriving from countries with war-related contexts (p =.017), were more at risk of developing mental disorders. Psychological distress (p =.004), depression (p =.001) and exposure to potentially traumatic events (p =.020) were predictors of mental disorder development. Conclusi
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- 2023
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6. Psychological flexibility in South Sudanese female refugees in Uganda as a mechanism for change within a guided self-help intervention
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Lakin, Daniel P., Cooper, Samuel E., Andersen, Lena, Brown, Felicity L., Augustinavicius, Jura L.S., Carswell, Kenneth, Leku, Marx, Adaku, Alex, Au, Teresa, Bryant, Richard, Garcia-Moreno, Claudia, White, Ross G., Tol, Wietse A., Lakin, Daniel P., Cooper, Samuel E., Andersen, Lena, Brown, Felicity L., Augustinavicius, Jura L.S., Carswell, Kenneth, Leku, Marx, Adaku, Alex, Au, Teresa, Bryant, Richard, Garcia-Moreno, Claudia, White, Ross G., and Tol, Wietse A.
- Abstract
Objective: To examine the role of psychological flexibility as a potential mediator in the relationship between involvement in a guided self-help intervention, Self-Help Plus, and psychological distress in a sample of South Sudanese refugee women living in northern Uganda. Method: We conducted secondary analysis of data from a cluster randomized controlled trial conducted in 2018. We used multilevel mediation modeling to explore the relationship of psychological flexibility, as measured by the Acceptance and Action Questionnaire (AAQ-II), as a mediating factor in the relationship between Self-Help Plus involvement and general psychological distress as measured by the Kessler Psychological Distress Scale–6 (K6). Results: We found strong multilevel mediation of decreased K6 scores in the treatment group by AAQ-II scores (multilevel b = −3.28). A more pronounced mediation effect was discovered immediately post intervention (b = −1.09) compared to 3-month follow-up (b = −0.84). This is in line with the current literature that demonstrates the role of psychological flexibility as a primary mechanism of change in ACT-based interventions. Conclusions: Psychological flexibility is a contributing component in the theory of change for this ACT-based intervention. Identifying the core components of interventions allows for more effective adaptation and implementation of relevant services, especially in low-resource contexts., OBJECTIVE: To examine the role of psychological flexibility as a potential mediator in the relationship between involvement in a guided self-help intervention, Self-Help Plus, and psychological distress in a sample of South Sudanese refugee women living in northern Uganda. METHOD: We conducted secondary analysis of data from a cluster randomized controlled trial conducted in 2018. We used multilevel mediation modeling to explore the relationship of psychological flexibility, as measured by the Acceptance and Action Questionnaire (AAQ-II), as a mediating factor in the relationship between Self-Help Plus involvement and general psychological distress as measured by the Kessler Psychological Distress Scale-6 (K6). RESULTS: We found strong multilevel mediation of decreased K6 scores in the treatment group by AAQ-II scores (multilevel b = -3.28). A more pronounced mediation effect was discovered immediately post intervention (b = -1.09) compared to 3-month follow-up (b = -0.84). This is in line with the current literature that demonstrates the role of psychological flexibility as a primary mechanism of change in ACT-based interventions. CONCLUSIONS: Psychological flexibility is a contributing component in the theory of change for this ACT-based intervention. Identifying the core components of interventions allows for more effective adaptation and implementation of relevant services, especially in low-resource contexts. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
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- 2023
7. Psychological flexibility in South Sudanese female refugees in Uganda as a mechanism for change within a guided self-help intervention.
- Author
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Lakin, Daniel P., primary, Cooper, Samuel E., additional, Andersen, Lena, additional, Brown, Felicity L., additional, Augustinavicius, Jura L. S., additional, Carswell, Kenneth, additional, Leku, Marx, additional, Adaku, Alex, additional, Au, Teresa, additional, Bryant, Richard, additional, Garcia-Moreno, Claudia, additional, White, Ross G., additional, and Tol, Wietse A., additional
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- 2023
- Full Text
- View/download PDF
8. Risk factors for mental disorder development in asylum seekers and refugees resettled in Western Europe and Turkey: Participant-level analysis of two large prevention studies
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Barbui, Corrado, primary, Tedeschi, Federico, additional, Acarturk, Ceren, additional, Anttila, Minna, additional, Au, Teresa, additional, Baumgartner, Josef, additional, Carswell, Ken, additional, Churchill, Rachel, additional, Cuijpers, Pim, additional, Karyotaki, Eirini, additional, Klein, Thomas, additional, Koesters, Markus, additional, Lantta, Tella, additional, Nosè, Michela, additional, Ostuzzi, Giovanni, additional, Pasquini, Massimo, additional, Prina, Eleonora, additional, Sijbrandij, Marit, additional, Tarsitani, Lorenzo, additional, Turrini, Giulia, additional, Uygun, Ersin, additional, Välimäki, Maritta, additional, Walker, Lauren, additional, Wancata, Johannes, additional, White, Ross G., additional, and Purgato, Marianna, additional
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- 2022
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9. A randomized controlled trial of an internet-based therapist-assisted indicated preventive intervention for prolonged grief disorder
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Litz, Brett T., Schorr, Yonit, Delaney, Eileen, Au, Teresa, Papa, Anthony, Fox, Annie B., Morris, Sue, Nickerson, Angela, Block, Susan, and Prigerson, Holly G.
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- 2014
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10. Cost-effectiveness of the Self-Help Plus Intervention for Adult Syrian Refugees Hosted in Turkey
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Park, A-La, primary, Waldmann, Tamara, additional, Kösters, Markus, additional, Tedeschi, Federico, additional, Nosè, Michela, additional, Ostuzzi, Giovanni, additional, Purgato, Marianna, additional, Turrini, Giulia, additional, Välimäki, Maritta, additional, Lantta, Tella, additional, Anttila, Minna, additional, Wancata, Johannes, additional, Friedrich, Fabian, additional, Acartürk, Ceren, additional, İlkkursun, Zeynep, additional, Uygun, Ersin, additional, Eskici, Sevde, additional, Cuijpers, Pim, additional, Sijbrandij, Marit, additional, White, Ross G., additional, Popa, Mariana, additional, Carswell, Kenneth, additional, Au, Teresa, additional, Kilian, Reinhold, additional, and Barbui, Corrado, additional
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- 2022
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11. Co-occurring posttraumatic stress and depression symptoms after sexual assault: A latent profile analysis
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Au, Teresa M., Dickstein, Benjamin D., Comer, Jonathan S., Salters-Pedneault, Kristalyn, and Litz, Brett T.
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- 2013
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12. Effectiveness of a WHO self-help psychological intervention for preventing mental disorders among Syrian refugees in Turkey: a randomized controlled trial
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Acarturk, Ceren, Uygun, Ersin, Ilkkursun, Zeynep, Carswell, Kenneth, Tedeschi, Federico, Batu, Mine, Eskici, Sevde, Kurt, Gulsah, Anttila, Minna, Au, Teresa, Baumgartner, Josef, Churchill, Rachel, Cuijpers, Pim, Becker, Thomas, Koesters, Markus, Lantta, Tella, Nosè, Michela, Ostuzzi, Giovanni, Popa, Mariana, Purgato, Marianna, Sijbrandij, Marit, Turrini, Giulia, Välimäki, Maritta, Walker, Lauren, Wancata, Johannes, Zanini, Elisa, White, Ross G., van Ommeren, Mark, Barbui, Corrado, Acarturk, Ceren, Uygun, Ersin, Ilkkursun, Zeynep, Carswell, Kenneth, Tedeschi, Federico, Batu, Mine, Eskici, Sevde, Kurt, Gulsah, Anttila, Minna, Au, Teresa, Baumgartner, Josef, Churchill, Rachel, Cuijpers, Pim, Becker, Thomas, Koesters, Markus, Lantta, Tella, Nosè, Michela, Ostuzzi, Giovanni, Popa, Mariana, Purgato, Marianna, Sijbrandij, Marit, Turrini, Giulia, Välimäki, Maritta, Walker, Lauren, Wancata, Johannes, Zanini, Elisa, White, Ross G., van Ommeren, Mark, and Barbui, Corrado
- Abstract
Refugees are at high risk of developing mental disorders. There is no evidence from randomized controlled trials (RCTs) that psychological interventions can prevent the onset of mental disorders in this group. We assessed the effectiveness of a self-help psychological intervention developed by the World Health Organization, called Self-Help Plus, in preventing the development of mental disorders among Syrian refugees experiencing psychological distress in Turkey. A two-arm, assessor-masked RCT was conducted in two Turkish areas. Eligible participants were adult Syrian refugees experiencing psychological distress (General Health Questionnaire ≥3), but without a diagnosis of mental disorder. They were randomly assigned either to the Self-Help Plus arm (consisting of Self-Help Plus combined with Enhanced Care as Usual, ECAU) or to ECAU only in a 1:1 ratio. Self-Help Plus was delivered in a group format by two facilitators over five sessions. The primary outcome measure was the presence of any mental disorder assessed by the Mini International Neuropsychiatric Interview at six-month follow-up. Secondary outcome measures were the presence of mental disorders at post-intervention, and psychological distress, symptoms of post-traumatic stress disorder and depression, personally identified psychological outcomes, functional impairment, subjective well-being, and quality of life at post-intervention and six-month follow-up. Between October 1, 2018 and November 30, 2019, 1,186 refugees were assessed for inclusion. Five hundred forty-four people were ineligible, and 642 participants were enrolled and randomly assigned to either Self-Help Plus (N=322) or ECAU (N=320). Self-Help Plus participants were significantly less likely to have any mental disorders at six-month follow-up compared to the ECAU group (21.69% vs. 40.73%; Cramer's V = 0.205, p<0.001, risk ratio: 0.533, 95% CI: 0.408-0.696). Analysis of secondary outcomes suggested that Self-Help Plus was not effective im
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- 2022
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13. Psychological Flexibility in South Sudanese Female Trauma Survivors in Uganda as a Mechanism for Change Within a Guided Self-Help Intervention
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Lakin, Daniel, primary, Cooper, Samuel Emerson, additional, Anderson, Lena, additional, Augustinavicius, Jura, additional, Brown, Felicity, additional, Carswell, Ken, additional, Leku, Marx Ronald, additional, Adaku, Alex, additional, Au, Teresa, additional, Bryant, Richard A., additional, Garcia-Moreno, Claudia, additional, White, Ross, additional, and Tol, Wietse A, additional
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- 2022
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14. sj-docx-1-isp-10.1177_00207640221132430 – Supplemental material for Risk factors for mental disorder development in asylum seekers and refugees resettled in Western Europe and Turkey: Participant-level analysis of two large prevention studies
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Barbui, Corrado, Tedeschi, Federico, Acarturk, Ceren, Anttila, Minna, Au, Teresa, Baumgartner, Josef, Carswell, Ken, Churchill, Rachel, Cuijpers, Pim, Karyotaki, Eirini, Klein, Thomas, Koesters, Markus, Lantta, Tella, Nosè, Michela, Ostuzzi, Giovanni, Pasquini, Massimo, Prina, Eleonora, Sijbrandij, Marit, Tarsitani, Lorenzo, Turrini, Giulia, Uygun, Ersin, Välimäki, Maritta, Walker, Lauren, Wancata, Johannes, White, Ross G., and Purgato, Marianna
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FOS: Psychology ,FOS: Clinical medicine ,170199 Psychology not elsewhere classified ,110319 Psychiatry (incl. Psychotherapy) - Abstract
Supplemental material, sj-docx-1-isp-10.1177_00207640221132430 for Risk factors for mental disorder development in asylum seekers and refugees resettled in Western Europe and Turkey: Participant-level analysis of two large prevention studies by Corrado Barbui, Federico Tedeschi, Ceren Acarturk, Minna Anttila, Teresa Au, Josef Baumgartner, Ken Carswell, Rachel Churchill, Pim Cuijpers, Eirini Karyotaki, Thomas Klein, Markus Koesters, Tella Lantta, Michela Nosè, Giovanni Ostuzzi, Massimo Pasquini, Eleonora Prina, Marit Sijbrandij, Lorenzo Tarsitani, Giulia Turrini, Ersin Uygun, Maritta Välimäki, Lauren Walker, Johannes Wancata, Ross G. White and Marianna Purgato in International Journal of Social Psychiatry
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- 2022
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15. Effectiveness of a WHO self‐help psychological intervention for preventing mental disorders among Syrian refugees in Turkey: a randomized controlled trial
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Acarturk, Ceren, primary, Uygun, Ersin, additional, Ilkkursun, Zeynep, additional, Carswell, Kenneth, additional, Tedeschi, Federico, additional, Batu, Mine, additional, Eskici, Sevde, additional, Kurt, Gulsah, additional, Anttila, Minna, additional, Au, Teresa, additional, Baumgartner, Josef, additional, Churchill, Rachel, additional, Cuijpers, Pim, additional, Becker, Thomas, additional, Koesters, Markus, additional, Lantta, Tella, additional, Nosè, Michela, additional, Ostuzzi, Giovanni, additional, Popa, Mariana, additional, Purgato, Marianna, additional, Sijbrandij, Marit, additional, Turrini, Giulia, additional, Välimäki, Maritta, additional, Walker, Lauren, additional, Wancata, Johannes, additional, Zanini, Elisa, additional, White, Ross G., additional, van Ommeren, Mark, additional, and Barbui, Corrado, additional
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- 2022
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16. Sustainable Technology for Adolescents and youth to Reduce Stress ( STARS ): a WHO transdiagnostic chatbot for distressed youth
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Hall, Jennifer, primary, Jordan, Stewart, additional, Ommeren, Mark, additional, Au, Teresa, additional, Sway, Rajiah Abu, additional, Crawford, Joy, additional, Ghalayani, Heba, additional, Hamdani, Syed Usman, additional, Luitel, Nagendra P., additional, Malik, Aiysha, additional, Servili, Chiara, additional, Sorsdahl, Katherine, additional, Watts, Sarah, additional, and Carswell, Kenneth, additional
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- 2022
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17. Self-Help Plus para Refugiados y solicitantes de asilo:Protocolo de Estudio para una serie de Meta-análisis de datos de participantes individuales
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Karyotaki, Eirini, Sijbrandij, Marit, Purgato, Marianna, Acarturk, Ceren, Lakin, Daniel, Bailey, Della, Peckham, Emily, Uygun, Ersin, Tedeschi, Federico, Wancata, Johannes, Augustinavicius, Jura, Carswell, Ken, Välimäki, Maritta, van Ommeren, Mark, Koesters, Markus, Popa, Mariana, Leku, Marx Ronald, Anttila, Minna, Churchill, Rachel, White, Ross, Al-Hashimi, Sarah, Lantta, Tella, Au, Teresa, Klein, Thomas, Tol, Wietse A., Cuijpers, Pim, and Barbui, Corrado
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Refugees ,depression ,individual participant data ,asylum seekers ,common mental disorders - Abstract
Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.
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- 2021
18. Effectiveness of Self-Help Plus in preventing mental disorders in refugees and asylum seekers in Western Europe: a multinational randomized controlled trial
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Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271); İlkkurşun, Zeynep, Purgato, Marianna; Carswell, Kenneth; Tedeschi, Federico; Anttila, Minna; Au, Teresa; Bajbouj, Malek; Baumgartner, Josef; Biondi, Massimo; Churchill, Rachel; Cuijpers, Pim; Koesters, Markus; Gastaldon, Chiara; Lantta, Tella; Nose, Michela; Ostuzzi, Giovanni; Papola, Davide; Popa, Mariana; Roselli, Valentina; Sijbrandij, Marit; Tarsitani, Lorenzo; Turrini, Giulia; Valimaki, Maritta; Walker, Lauren; Wancata, Johannes; Zanini, Elisa; White, Ross; van Ommeren, Mark; Barbui, Corrado, Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271); İlkkurşun, Zeynep, and Purgato, Marianna; Carswell, Kenneth; Tedeschi, Federico; Anttila, Minna; Au, Teresa; Bajbouj, Malek; Baumgartner, Josef; Biondi, Massimo; Churchill, Rachel; Cuijpers, Pim; Koesters, Markus; Gastaldon, Chiara; Lantta, Tella; Nose, Michela; Ostuzzi, Giovanni; Papola, Davide; Popa, Mariana; Roselli, Valentina; Sijbrandij, Marit; Tarsitani, Lorenzo; Turrini, Giulia; Valimaki, Maritta; Walker, Lauren; Wancata, Johannes; Zanini, Elisa; White, Ross; van Ommeren, Mark; Barbui, Corrado
- Abstract
Introduction: Self-Help Plus (SH+) is a group-based psychological intervention developed by the World Health Organization for managing stress. Objective: to assess the effectiveness of SH+ in preventing mental disorders in refugees and asylum seekers in Western Europe. Methods: we conducted a randomized controlled trial in 5 European countries. Refugees and asylum seekers with psychological distress (General Health Questionnaire score >= 3), but without a Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) or ICD/10 diagnosis of mental disorder, as assessed with the Mini International Neuropsychiatric Interview (MINI), were randomized to SH+ or enhanced treatment as usual (ETAU). The primary outcome was the frequency of mental disorders with the MINI at 6 months. Secondary outcomes included the frequency of mental disorders at postintervention, self-identified problems, psychological symptoms, and other outcomes. Results: four hundred fifty-nine individuals were randomly assigned to SH+ or ETAU. For the primary outcome, we found no difference in the frequency of mental disorders at 6 months (Cramer V = 0.007, p = 0.90, RR = 0.96; 95% CI 0.52-1.78), while the difference significantly favored SH+ at after the intervention (secondary outcome, measured within 2 weeks from the last session; Cramer V = 0.13, p = 0.01, RR = 0.50; 95% CI 0.29-0.87). Conclusions: this is the first randomized indicated prevention study with the aim of preventing the onset of mental disorders in asylum seekers and refugees in Western Europe. As a prevention effect of SH+ was not observed at 6 months, but rather after the intervention only, modalities to maintain its beneficial effect in the long term need to be identified.
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- 2021
19. Self-Help Plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses
- Author
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Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), Karyotaki, Eirini; Sijbrandij, Marit; Purgato, Marianna; Lakin, Daniel; Bailey, Della; Peckham, Emily; Uygun, Ersin; Tedeschi, Federico; Wancata, Johannes; Augustinavicius, Jura; Carswell, Ken; Valimaki, Maritta; van Ommeren, Mark; Koesters, Markus; Popa, Mariana; Leku, Marx Ronald; Anttila, Minna; Churchill, Rachel; White, Ross; Al-Hashimi, Sarah; Lantta, Tella; Au, Teresa; Klein, Thomas; Tol, Wietse A.; Cuijpers, Pim; Barbui, Corrado, Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), and Karyotaki, Eirini; Sijbrandij, Marit; Purgato, Marianna; Lakin, Daniel; Bailey, Della; Peckham, Emily; Uygun, Ersin; Tedeschi, Federico; Wancata, Johannes; Augustinavicius, Jura; Carswell, Ken; Valimaki, Maritta; van Ommeren, Mark; Koesters, Markus; Popa, Mariana; Leku, Marx Ronald; Anttila, Minna; Churchill, Rachel; White, Ross; Al-Hashimi, Sarah; Lantta, Tella; Au, Teresa; Klein, Thomas; Tol, Wietse A.; Cuijpers, Pim; Barbui, Corrado
- Abstract
Background: refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: this protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: these results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.
- Published
- 2021
20. Self-Help Plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses
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Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), Karyotaki, Eirini; Sijbrandij, Marit; Purgato, Marianna; Lakin, Daniel; Bailey, Della; Peckham, Emily; Uygun, Ersin; Tedeschi, Federico; Wancata, Johannes; Augustinavicius, Jura; Carswell, Ken; Valimaki, Maritta; van Ommeren, Mark; Koesters, Markus; Popa, Mariana; Leku, Marx Ronald; Anttila, Minna; Churchill, Rachel; White, Ross; Al-Hashimi, Sarah; Lantta, Tella; Au, Teresa; Klein, Thomas; Tol, Wietse A.; Cuijpers, Pim; Barbui, Corrado, College of Social Sciences and Humanities, Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), Karyotaki, Eirini; Sijbrandij, Marit; Purgato, Marianna; Lakin, Daniel; Bailey, Della; Peckham, Emily; Uygun, Ersin; Tedeschi, Federico; Wancata, Johannes; Augustinavicius, Jura; Carswell, Ken; Valimaki, Maritta; van Ommeren, Mark; Koesters, Markus; Popa, Mariana; Leku, Marx Ronald; Anttila, Minna; Churchill, Rachel; White, Ross; Al-Hashimi, Sarah; Lantta, Tella; Au, Teresa; Klein, Thomas; Tol, Wietse A.; Cuijpers, Pim; Barbui, Corrado, College of Social Sciences and Humanities, and Department of Psychology
- Abstract
Background: refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: this protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: these results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals., European Union (EU); Horizon 2020; European Commission (EC); RE-DEFINE: Refugee Emergency: DEFining and Implementing Novel Evidence-based Psychosocial Interventions
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- 2021
21. Effectiveness of Self-Help Plus in preventing mental disorders in refugees and asylum seekers in Western Europe: a multinational randomized controlled trial
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Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271); İlkkurşun, Zeynep, Purgato, Marianna; Carswell, Kenneth; Tedeschi, Federico; Anttila, Minna; Au, Teresa; Bajbouj, Malek; Baumgartner, Josef; Biondi, Massimo; Churchill, Rachel; Cuijpers, Pim; Koesters, Markus; Gastaldon, Chiara; Lantta, Tella; Nose, Michela; Ostuzzi, Giovanni; Papola, Davide; Popa, Mariana; Roselli, Valentina; Sijbrandij, Marit; Tarsitani, Lorenzo; Turrini, Giulia; Valimaki, Maritta; Walker, Lauren; Wancata, Johannes; Zanini, Elisa; White, Ross; van Ommeren, Mark; Barbui, Corrado, College of Social Sciences and Humanities; Graduate School of Social Sciences and Humanities, Department of Psychology, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271); İlkkurşun, Zeynep, Purgato, Marianna; Carswell, Kenneth; Tedeschi, Federico; Anttila, Minna; Au, Teresa; Bajbouj, Malek; Baumgartner, Josef; Biondi, Massimo; Churchill, Rachel; Cuijpers, Pim; Koesters, Markus; Gastaldon, Chiara; Lantta, Tella; Nose, Michela; Ostuzzi, Giovanni; Papola, Davide; Popa, Mariana; Roselli, Valentina; Sijbrandij, Marit; Tarsitani, Lorenzo; Turrini, Giulia; Valimaki, Maritta; Walker, Lauren; Wancata, Johannes; Zanini, Elisa; White, Ross; van Ommeren, Mark; Barbui, Corrado, College of Social Sciences and Humanities; Graduate School of Social Sciences and Humanities, and Department of Psychology
- Abstract
Introduction: Self-Help Plus (SH+) is a group-based psychological intervention developed by the World Health Organization for managing stress. Objective: to assess the effectiveness of SH+ in preventing mental disorders in refugees and asylum seekers in Western Europe. Methods: we conducted a randomized controlled trial in 5 European countries. Refugees and asylum seekers with psychological distress (General Health Questionnaire score >= 3), but without a Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) or ICD/10 diagnosis of mental disorder, as assessed with the Mini International Neuropsychiatric Interview (MINI), were randomized to SH+ or enhanced treatment as usual (ETAU). The primary outcome was the frequency of mental disorders with the MINI at 6 months. Secondary outcomes included the frequency of mental disorders at postintervention, self-identified problems, psychological symptoms, and other outcomes. Results: four hundred fifty-nine individuals were randomly assigned to SH+ or ETAU. For the primary outcome, we found no difference in the frequency of mental disorders at 6 months (Cramer V = 0.007, p = 0.90, RR = 0.96; 95% CI 0.52-1.78), while the difference significantly favored SH+ at after the intervention (secondary outcome, measured within 2 weeks from the last session; Cramer V = 0.13, p = 0.01, RR = 0.50; 95% CI 0.29-0.87). Conclusions: this is the first randomized indicated prevention study with the aim of preventing the onset of mental disorders in asylum seekers and refugees in Western Europe. As a prevention effect of SH+ was not observed at 6 months, but rather after the intervention only, modalities to maintain its beneficial effect in the long term need to be identified., European Union (EU); Horizon 2020; European Commission (EC); RE-DEFINE: Refugee Emergency: DEFining and Implementing Novel Evidence-based Psychosocial Interventions
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- 2021
22. Plan de negocios para la venta accesible de ropa Low Cost en Lima Metropolitana
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Fernández Zegarra, Sandra Rosa, Quiñe Au, Teresa Elizabeth, Yauri Villegas, Helvia Helen, and Ossio Sal y Rosas, Carlos Eduardo
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Administración de empresas ,Industria textil ,Proyectos de inversión ,Producción y comercialización ,purl.org/pe-repo/ocde/ford#5.02.04 [https] - Abstract
Este trabajo describe un “Plan de Negocios para la Venta Accesible de Ropa Low Cost en Lima Metropolitana”; con esta propuesta buscamos atender la necesidad de adquisición de prendas con inmediatez, congruencia entre precio, calidad y estilo al alcance de la mano. Contaremos con una tienda móvil usando un camión que nos permitirá llegar a los diferentes distritos de Lima, iniciando nuestras operaciones en los distritos de Santiago de Surco y San Isidro, focalizando el alcance en mujeres entre 18 y 50 años de los niveles socioeconómicos B y C; cuyo poder adquisitivo permitirá realizar compras de una manera más atractiva de productos low cost con prendas seleccionadas de marcas reconocidas. Trabajo de Investigación
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- 2020
23. Guided self-help to reduce psychological distress in South Sudanese female refugees in Uganda:a cluster randomised trial
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Tol, Wietse A., Leku, Marx R., Lakin, Daniel P., Carswell, Kenneth, Augustinavicius, Jura, Adaku, Alex, Au, Teresa M., Brown, Felicity L., Bryant, Richard A., Garcia-Moreno, Claudia, Musci, Rashelle J., Ventevogel, Peter, White, Ross G., van Ommeren, Mark, Tol, Wietse A., Leku, Marx R., Lakin, Daniel P., Carswell, Kenneth, Augustinavicius, Jura, Adaku, Alex, Au, Teresa M., Brown, Felicity L., Bryant, Richard A., Garcia-Moreno, Claudia, Musci, Rashelle J., Ventevogel, Peter, White, Ross G., and van Ommeren, Mark
- Abstract
Background: Innovative solutions are required to provide mental health support at scale in low-resource humanitarian contexts. We aimed to assess the effectiveness of a facilitator-guided, group-based, self-help intervention (Self-Help Plus) to reduce psychological distress in female refugees. Methods: We did a cluster randomised trial in rural refugee settlements in northern Uganda. Participants were female South Sudanese refugees with at least moderate levels of psychological distress (cutoff ≥5 on the Kessler 6). The intervention comprised access to usual care and five 2-h audio-recorded stress-management workshops (20–30 refugees) led by briefly trained lay facilitators, accompanied by an illustrated self-help book. Villages were randomly assigned to either intervention (Self-Help Plus or enhanced usual care) on a 1:1 basis. Within 14 villages, randomly selected households were approached. Screening of women in households continued until 20–30 eligible participants were identified per site. The primary outcome was individual psychological distress, assessed using the Kessler 6 symptom checklist 1 week before, 1 week after, and 3 months after intervention, in the intention-to-treat population. All outcomes were measured at the individual (rather than cluster) level. Secondary outcomes included personally identified problems, post-traumatic stress, depression symptoms, feelings of anger, social interactions with other ethnic groups, functional impairment, and subjective wellbeing. Assessors were masked to allocation. This trial was prospectively registered at ISRCTN, number 50148022. Findings: Of 694 eligible participants (331 Self-Help Plus, 363 enhanced usual care), 613 (88%) completed all assessments. Compared with controls, we found stronger improvements for Self-Help Plus on psychological distress 3 months post intervention (β −1·20, 95% CI −2·33 to −0·08; p=0·04; d −0·26). We also found larger improvements for Self-Help Plus 3 months post-intervention for
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- 2020
24. Individual Approaches to Prevention and Early Intervention
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Au, Teresa M., primary, Silva, Caroline, additional, Delaney, Eileen M., additional, and Litz, Brett T., additional
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- 2012
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25. Effectiveness of Self-Help Plus in Preventing Mental Disorders in Refugees and Asylum Seekers in Western Europe: A Multinational Randomized Controlled Trial
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Purgato, Marianna, primary, Carswell, Kenneth, additional, Tedeschi, Federico, additional, Acarturk, Ceren, additional, Anttila, Minna, additional, Au, Teresa, additional, Bajbouj, Malek, additional, Baumgartner, Josef, additional, Biondi, Massimo, additional, Churchill, Rachel, additional, Cuijpers, Pim, additional, Koesters, Markus, additional, Gastaldon, Chiara, additional, Ilkkursun, Zeynep, additional, Lantta, Tella, additional, Nosè, Michela, additional, Ostuzzi, Giovanni, additional, Papola, Davide, additional, Popa, Mariana, additional, Roselli, Valentina, additional, Sijbrandij, Marit, additional, Tarsitani, Lorenzo, additional, Turrini, Giulia, additional, Välimäki, Maritta, additional, Walker, Lauren, additional, Wancata, Johannes, additional, Zanini, Elisa, additional, White, Ross, additional, van Ommeren, Mark, additional, and Barbui, Corrado, additional
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- 2021
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26. Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses
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Karyotaki, Eirini, primary, Sijbrandij, Marit, additional, Purgato, Marianna, additional, Acarturk, Ceren, additional, Lakin, Daniel, additional, Bailey, Della, additional, Peckham, Emily, additional, Uygun, Ersin, additional, Tedeschi, Federico, additional, Wancata, Johannes, additional, Augustinavicius, Jura, additional, Carswell, Ken, additional, Välimäki, Maritta, additional, van Ommeren, Mark, additional, Koesters, Markus, additional, Popa, Mariana, additional, Leku, Marx Ronald, additional, Anttila, Minna, additional, Churchill, Rachel, additional, White, Ross, additional, Al-Hashimi, Sarah, additional, Lantta, Tella, additional, Au, Teresa, additional, Klein, Thomas, additional, Tol, Wietse A., additional, Cuijpers, Pim, additional, and Barbui, Corrado, additional
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- 2021
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27. Differential social regulation of two pituitary gonadotropin-releasing hormone receptors
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Au, Teresa M., Greenwood, Anna K., and Fernald, Russell D.
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- 2006
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28. Effectiveness of a WHOself‐help psychological intervention for preventing mental disorders among Syrian refugees in Turkey: a randomized controlled trial
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Acarturk, Ceren, Uygun, Ersin, Ilkkursun, Zeynep, Carswell, Kenneth, Tedeschi, Federico, Batu, Mine, Eskici, Sevde, Kurt, Gulsah, Anttila, Minna, Au, Teresa, Baumgartner, Josef, Churchill, Rachel, Cuijpers, Pim, Becker, Thomas, Koesters, Markus, Lantta, Tella, Nosè, Michela, Ostuzzi, Giovanni, Popa, Mariana, Purgato, Marianna, Sijbrandij, Marit, Turrini, Giulia, Välimäki, Maritta, Walker, Lauren, Wancata, Johannes, Zanini, Elisa, White, Ross G., Ommeren, Mark, and Barbui, Corrado
- Abstract
Refugees are at high risk of developing mental disorders. There is no evidence from randomized controlled trials (RCTs) that psychological interventions can prevent the onset of mental disorders in this group. We assessed the effectiveness of a self‐help psychological intervention developed by the World Health Organization, called Self‐Help Plus, in preventing the development of mental disorders among Syrian refugees experiencing psychological distress in Turkey. A two‐arm, assessor‐masked RCT was conducted in two Turkish areas. Eligible participants were adult Syrian refugees experiencing psychological distress (General Health Questionnaire ≥3), but without a diagnosis of mental disorder. They were randomly assigned either to the Self‐Help Plus arm (consisting of Self‐Help Plus combined with Enhanced Care as Usual, ECAU) or to ECAU only in a 1:1 ratio. Self‐Help Plus was delivered in a group format by two facilitators over five sessions. The primary outcome measure was the presence of any mental disorder assessed by the Mini International Neuropsychiatric Interview at six‐month follow‐up. Secondary outcome measures were the presence of mental disorders at post‐intervention, and psychological distress, symptoms of post‐traumatic stress disorder and depression, personally identified psychological outcomes, functional impairment, subjective well‐being, and quality of life at post‐intervention and six‐month follow‐up. Between October 1, 2018 and November 30, 2019, 1,186 refugees were assessed for inclusion. Five hundred forty‐four people were ineligible, and 642 participants were enrolled and randomly assigned to either Self‐Help Plus (N=322) or ECAU (N=320). Self‐Help Plus participants were significantly less likely to have any mental disorders at six‐month follow‐up compared to the ECAU group (21.69% vs. 40.73%; Cramer's V = 0.205, p<0.001, risk ratio: 0.533, 95% CI: 0.408‐0.696). Analysis of secondary outcomes suggested that Self‐Help Plus was not effective immediately post‐intervention, but was associated with beneficial effects at six‐month follow‐up in terms of symptoms of depression, personally identified psychological outcomes, and quality of life. This is the first prevention RCT ever conducted among refugees experiencing psychological distress but without a mental disorder. Self‐Help Plus was found to be an effective strategy for preventing the onset of mental disorders. Based on these findings, this low‐intensity self‐help psychological intervention could be scaled up as a public health strategy to prevent mental disorders in refugee populations exposed to ongoing adversities.
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- 2022
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29. Effectiveness and cost-effectiveness of Self-Help Plus (SH+) for preventing mental disorders in refugees and asylum seekers in Europe and Turkey: study protocols for two randomised controlled trials
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Purgato, Marianna, primary, Carswell, Kenneth, additional, Acarturk, Ceren, additional, Au, Teresa, additional, Akbai, Sena, additional, Anttila, Minna, additional, Baumgartner, Josef, additional, Bailey, Della, additional, Biondi, Massimo, additional, Bird, Martha, additional, Churchill, Rachel, additional, Eskici, Sevde, additional, Hansen, Louise Juul, additional, Heron, Paul, additional, Ilkkursun, Zeynep, additional, Kilian, Reinhold, additional, Koesters, Markus, additional, Lantta, Tella, additional, Nosè, Michela, additional, Ostuzzi, Giovanni, additional, Papola, Davide, additional, Popa, Mariana, additional, Sijbrandij, Marit, additional, Tarsitani, Lorenzo, additional, Tedeschi, Federico, additional, Turrini, Giulia, additional, Uygun, Ersin, additional, Välimäki, Maritta Anneli, additional, Wancata, Johannes, additional, White, Ross, additional, Zanini, Elisa, additional, Cuijpers, Pim, additional, Barbui, Corrado, additional, and Van Ommeren, Mark, additional
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- 2019
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30. Treatment seeking behaviour in southern Chinese elders with chronic orofacial pain: a qualitative study
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Au, Teresa SY, primary, Wong, May CM, additional, McMillan, Anne S, additional, Bridges, Susan, additional, and McGrath, Colman, additional
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- 2014
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31. Psychometric Evaluation of the Moral Injury Events Scale
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Nash, William P., primary, Marino Carper, Teresa L., additional, Mills, Mary Alice, additional, Au, Teresa, additional, Goldsmith, Abigail, additional, and Litz, Brett T., additional
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- 2013
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32. Moral Injury Events Scale
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Nash, William P., primary, Carper, Teresa L. Marino, additional, Mills, Mary Alice, additional, Au, Teresa, additional, Goldsmith, Abigail, additional, and Litz, Brett T., additional
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- 2013
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33. Sustainable Technology for Adolescents and youth to Reduce Stress (STARS): a WHOtransdiagnostic chatbot for distressed youth
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Hall, Jennifer, Jordan, Stewart, Ommeren, Mark, Au, Teresa, Sway, Rajiah Abu, Crawford, Joy, Ghalayani, Heba, Hamdani, Syed Usman, Luitel, Nagendra P., Malik, Aiysha, Servili, Chiara, Sorsdahl, Katherine, Watts, Sarah, and Carswell, Kenneth
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- 2022
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34. Self-Help Plus for refugees and asylum seekers: an individual participant data meta-analysis
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Karyotaki, Eirini, Sijbrandij, Marit, Purgato, Marianna, Acarturk, Ceren, Lakin, Daniel, Bailey, Della, Peckham, Emily, Uygun, Ersin, Tedeschi, Federico, Wancata, Johannes, Augustinavicius, Jura, Carswell, Kenneth, Va¨lima¨ki, Maritta, van Ommeren, Mark, Koesters, Markus, Popa, Mariana, Leku, Marx Ronald, Anttila, Minna, Churchill, Rachel, White, Ross G, Al-Hashimi, Sarah, Lantta, Tella, Au, Teresa, Klein, Thomas, Tol, Wietse A, Cuijpers, Pim, and Barbui, Corrado
- Abstract
QuestionRefugees and asylum seekers are at high risk of mental disorders due to various stressors before, during and after forceful displacement. The WHO Self-Help Plus (SH+) intervention was developed to manage psychological distress and a broad range of mental health symptoms in vulnerable populations. This study aimed to examine the effects and moderators of SH+ compared with Enhanced Care as Usual (ECAU) in reducing depressive symptoms among refugees and asylum seekers.Study selection and analysisThree randomised trials were identified with 1795 individual participant data (IPD). We performed an IPD meta-analysis to estimate the effects of SH+, primarily on depressive symptoms and second on post-traumatic stress, well-being, self-identified problems and functioning. Effects were also estimated at 5–6 months postrandomisation (midterm).FindingsThere was no evidence of a difference between SH+ and ECAU+ in reducing depressive symptoms at postintervention. However, SH+ had significantly larger effects among participants who were not employed (β=1.60, 95% CI 0.20 to 3.00) and had lower mental well-being levels (β=0.02, 95% CI 0.001 to 0.05). At midterm, SH+ was significantly more effective than ECAU in improving depressive symptoms (β=−1.13, 95% CI −1.99 to −0.26), self-identified problems (β=−1.56, 95% CI −2.54 to −0.59) and well-being (β=6.22, 95% CI 1.60 to 10.90).ConclusionsAlthough SH+ did not differ significantly from ECAU in reducing symptoms of depression at postintervention, it did present benefits for particularly vulnerable participants (ie, unemployed and with lower mental well-being levels), and benefits were also evident at midterm follow-up. These results are promising for the use of SH+ in the management of depressive symptoms and improvement of well-being and self-identified problems among refugees and asylum seekers.
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- 2023
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35. The OCEA awards of merit.
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Au, Teresa
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- *
CIVIL engineering - Abstract
Presents the Outstanding Civil Engineering Achievement Awards of Merit. Bendway weirs along the Mississippi River; Ex planation of bedway weirs; Improvements realized; The Bad Creek Pumped Storage Project; Components and operation of the proj ect; Benefits derived; Associated environmental development; The American Airlines maintenance facility in Fort Worth, Texas ; Description of the project; Functions of the facility; The structural system; Cantilevered roof; Design concerns.
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- 1992
36. Cost-effectiveness of the Self-Help Plus intervention for adult Syrian refugees hosted in Turkey
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Park, A-La, Waldmann, Tamara, Kösters, Markus, Tedeschi, Federico, Nosè, Michela, Ostuzzi, Giovanni, Purgato, Marianna, Turrini, Giulia, Välimäki, Maritta, Lantta, Tella, Anttila, Minna, Wancata, Johannes, Friedrich, Fabian, Acartürk, Ceren, İlkkursun, Zeynep, Uygun, Ersin, Eskici, Sevde, Cuijpers, Pim, Sijbrandij, Marit, White, Ross G., Popa, Mariana, Carswell, Kenneth, Au, Teresa, Kilian, Reinhold, Barbui, Corrado, Park, A-La, Waldmann, Tamara, Kösters, Markus, Tedeschi, Federico, Nosè, Michela, Ostuzzi, Giovanni, Purgato, Marianna, Turrini, Giulia, Välimäki, Maritta, Lantta, Tella, Anttila, Minna, Wancata, Johannes, Friedrich, Fabian, Acartürk, Ceren, İlkkursun, Zeynep, Uygun, Ersin, Eskici, Sevde, Cuijpers, Pim, Sijbrandij, Marit, White, Ross G., Popa, Mariana, Carswell, Kenneth, Au, Teresa, Kilian, Reinhold, and Barbui, Corrado
- Abstract
IMPORTANCE The cost-effectiveness of the Self-Help Plus (SH+) program, a group-based, guided, self-help psychological intervention developed by the World Health Organization for people affected by adversity, is unclear. OBJECTIVE To investigate the cost-utility of providing the SH+ intervention combined with enhanced usual care vs enhanced usual care alone for Syrian refugees or asylum seekers hosted in Turkey. DESIGN, SETTING, AND PARTICIPANTS This economic evaluation was performed as a prespecified part of an assessor-blinded randomized clinical trial conducted between October 1, 2018, and November 30, 2019, with 6-month follow-up. A total of 627 adults with psychological distress but no diagnosed psychiatric disorder were randomly assigned to the intervention group or the enhanced usual care group. INTERVENTIONS The SH+ program was a 5-session (2 hours each), group-based, stress management course in which participants learned self-help skills for managing stress by listening to audio sessions. The SH+ sessions were facilitated by briefly trained, nonspecialist individuals, and an illustrated book was provided to group members. Th intervention group received the SH+ intervention plus enhanced usual care; the control group received only enhanced usual care from the local health care system. Enhanced usual care included access to free health care services provided by primary and secondary institutions plus details on nongovernmental organizations and freely available mental health services, social services, and community networks for people under temporary protection of Turkey and refugees. MAIN OUTCOMES AND MEASURES The primary outcome measure was incremental cost per quality-adjusted life-year (QALY) gained from the perspective of the Turkish health care system. An intention-to-treat analysis was used including all participants who were randomized and for whom baseline data on costs and QALYs were available. Data were analyzed September 30, 2020, to July 30, 2021.
37. Developing and evaluating a compassion-based therapy for trauma-related shame and posttraumatic stress
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Au, Teresa Mingchi
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- Clinical psychology, PTSD, Self-compassion, Sexual assault, Shame, Trauma
- Abstract
Posttraumatic Stress Disorder (PTSD) has been primarily conceptualized as a fear-based disorder, but accumulating research indicates that shame can also strongly contribute to the development and maintenance of PTSD. Existing evidence-based treatments for PTSD typically focus on dysregulated fear responding and do not directly target the affective experience of shame. Interventions that promote self-compassion have shown promise for reducing shame related to various clinical problems, but this approach has not been systematically evaluated in traumatized individuals. The aim of this study was to develop and evaluate a brief compassion-based therapy, with the hypothesis that it would reduce trauma-related shame and PTSD symptoms. The intervention consisted of six weekly individual therapy sessions focused on promoting self-compassion in response to a traumatic event and its sequelae. Using a multiple baseline design, the intervention was evaluated in a community sample of trauma-exposed adults (N = 10) with elevated shame and PTSD symptoms. Participants completed assessments on a weekly basis during a 2-, 4-, or 6-week baseline phase and 6-week treatment phase, and at 2- and 4-weeks after the intervention. By the end of treatment, 90% of participants demonstrated reliable decreases in PTSD symptom severity (p < .05), while 80% of participants showed reliable reductions in shame (p < .05), relative to their respective scores at baseline. These improvements were maintained at 2- and 4-week follow-up, with large effect sizes for PTSD symptom severity (d = 2.26) and shame (d = 2.12), compared to scores at baseline. The intervention was also associated with improvements in self-blame (d = 2.61), self-compassion (d = 2.28), mindfulness (d = 2.21), positive affect (d = 1.07), and negative affect (d = 2.14). Greater increases in self-compassion from baseline to follow-up were correlated with greater reductions in PTSD symptom severity (r = -.76, p < .05) and in shame (r = -.79, p < .01). Participants reported high levels of satisfaction with the intervention. The results from the present study support the hypothesis that compassion-based therapy is associated with reductions in trauma-related shame and PTSD symptoms. The marked improvements observed during the relatively brief intervention suggest that the intervention may be useful as either a stand-alone treatment or as a supplement to other treatments.
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- 2015
38. Effectiveness of Self-Help plus in Preventing Mental Disorders in Refugees and Asylum Seekers in Western Europe: A Multinational Randomized Controlled Trial
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Corrado Barbui, Ross G. White, Johannes Wancata, Lorenzo Tarsitani, Tella Lantta, Malek Bajbouj, Rachel Churchill, Marianna Purgato, Josef Baumgartner, Marit Sijbrandij, Giulia Turrini, Teresa Au, Ceren Acarturk, Maritta Välimäki, Michela Nosè, Elisa Zanini, Pim Cuijpers, Lauren Walker, Minna Anttila, Giovanni Ostuzzi, Mariana Popa, Federico Tedeschi, Zeynep Ilkkursun, Davide Papola, Valentina Roselli, Mark van Ommeren, Massimo Biondi, Kenneth Carswell, Chiara Gastaldon, Markus Koesters, Clinical Psychology, World Health Organization (WHO) Collaborating Center, APH - Global Health, APH - Mental Health, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), İlkkurşun, Zeynep, Purgato, Marianna, Carswell, Kenneth, Tedeschi, Federico, Anttila, Minna, Au, Teresa, Bajbouj, Malek, Baumgartner, Josef, Biondi, Massimo, Churchill, Rachel, Cuijpers, Pim, Koesters, Markus, Gastaldon, Chiara, Lantta, Tella, Nose, Michela, Ostuzzi, Giovanni, Papola, Davide, Popa, Mariana, Roselli, Valentina, Sijbrandij, Marit, Tarsitani, Lorenzo, Turrini, Giulia, Valimaki, Maritta, Walker, Lauren, Wancata, Johannes, Zanini, Elisa, White, Ross, van Ommeren, Mark, Barbui, Corrado, College of Social Sciences and Humanities, Graduate School of Social Sciences and Humanities, and Department of Psychology
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Adult ,medicine.medical_specialty ,Refugee ,Asylum seekers ,Psychological intervention ,Psychological Distress ,Psychological well-being ,law.invention ,Stress Disorders, Post-Traumatic ,Standard Research Article ,SDG 3 - Good Health and Well-being ,Randomized controlled trial ,law ,Intervention (counseling) ,Psychological trauma ,medicine ,Humans ,Psychiatry ,Psychology ,Applied Psychology ,Stress Disorders ,Mini-international neuropsychiatric interview ,Refugees ,business.industry ,Mental Disorders ,Self-Help Plus ,SDG 16 - Peace, Justice and Strong Institutions ,Psychological stress ,Self-help Plus ,Europe ,General Medicine ,SDG 10 - Reduced Inequalities ,medicine.disease ,Psychiatry and Mental health ,Clinical Psychology ,Post-Traumatic ,General Health Questionnaire ,business - Abstract
Introduction: Self-Help Plus (SH+) is a group-based psychological intervention developed by the World Health Organization for managing stress. Objective: to assess the effectiveness of SH+ in preventing mental disorders in refugees and asylum seekers in Western Europe. Methods: we conducted a randomized controlled trial in 5 European countries. Refugees and asylum seekers with psychological distress (General Health Questionnaire score >= 3), but without a Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) or ICD/10 diagnosis of mental disorder, as assessed with the Mini International Neuropsychiatric Interview (MINI), were randomized to SH+ or enhanced treatment as usual (ETAU). The primary outcome was the frequency of mental disorders with the MINI at 6 months. Secondary outcomes included the frequency of mental disorders at postintervention, self-identified problems, psychological symptoms, and other outcomes. Results: four hundred fifty-nine individuals were randomly assigned to SH+ or ETAU. For the primary outcome, we found no difference in the frequency of mental disorders at 6 months (Cramer V = 0.007, p = 0.90, RR = 0.96; 95% CI 0.52-1.78), while the difference significantly favored SH+ at after the intervention (secondary outcome, measured within 2 weeks from the last session; Cramer V = 0.13, p = 0.01, RR = 0.50; 95% CI 0.29-0.87). Conclusions: this is the first randomized indicated prevention study with the aim of preventing the onset of mental disorders in asylum seekers and refugees in Western Europe. As a prevention effect of SH+ was not observed at 6 months, but rather after the intervention only, modalities to maintain its beneficial effect in the long term need to be identified., European Union (EU); Horizon 2020; European Commission (EC); RE-DEFINE: Refugee Emergency: DEFining and Implementing Novel Evidence-based Psychosocial Interventions
- Published
- 2021
39. Self-Help Plus para refugiados y solicitantes de asilo; protocolo de estudio para una serie de meta-análisis de datos de participantes individuales
- Author
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Eirini Karyotaki, Johannes Wancata, Mark van Ommeren, Ken Carswell, Marit Sijbrandij, Ross G. White, Sarah Al-Hashimi, Federico Tedeschi, Tella Lantta, Mariana Popa, Marianna Purgato, Maritta Välimäki, Pim Cuijpers, Teresa Au, Wietse A. Tol, Ceren Acarturk, Rachel Churchill, Thomas Klein, Markus Koesters, Minna Anttila, Daniel P. Lakin, Emily Peckham, Jura Augustinavicius, Marx R. Leku, Corrado Barbui, Ersin Uygun, Della Bailey, Acartürk, Zeynep Ceren (ORCID 0000-0001-7093-1554 & YÖK ID 39271), Karyotaki, Eirini, Sijbrandij, Marit, Purgato, Marianna, Lakin, Daniel, Bailey, Della, Peckham, Emily, Uygun, Ersin, Tedeschi, Federico, Wancata, Johannes, Augustinavicius, Jura, Carswell, Ken, Valimaki, Maritta, van Ommeren, Mark, Koesters, Markus, Popa, Mariana, Leku, Marx Ronald, Anttila, Minna, Churchill, Rachel, White, Ross, Al-Hashimi, Sarah, Lantta, Tella, Au, Teresa, Klein, Thomas, Tol, Wietse A., Cuijpers, Pim, Barbui, Corrado, College of Social Sciences and Humanities, and Department of Psychology
- Subjects
datos de participantes individuales ,Male ,RC435-571 ,Psychological intervention ,depresión ,Psychology ,Psychiatry ,Refugees ,Asylum seekers ,Individual participant data ,Depression ,Common mental disorders ,难民 ,Logistic regression ,Social and Behavioral Sciences ,solicitantes de asilo ,Psychological Distress ,Stress Disorders, Post-Traumatic ,Study Protocol ,0302 clinical medicine ,Clinical Protocols ,Cumulative incidence ,030212 general & internal medicine ,common mental disorders ,education.field_of_study ,Mental Disorders ,Middle Aged ,3. Good health ,FOS: Sociology ,FOS: Psychology ,trastornos de salud mental comunes ,Female ,个人参与者数据 ,Research Article ,asylum seekers ,Adult ,medicine.medical_specialty ,Social Work ,Refugee ,Population ,寻求庇护者 ,抑郁 ,refugees ,depression ,prevention ,self-help ,individual participant data meta-analysis ,常见精神障碍 ,03 medical and health sciences ,Quality of life (healthcare) ,Intervention (counseling) ,medicine ,Humans ,education ,Stressor ,individual participant data ,refugiados ,030227 psychiatry - Abstract
Background Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals., HIGHLIGHTS Refugees and asylum seekers face enormous challenges and, thus, are at risk of mental disorders. Low-intensity psychotherapeutic interventions are needed to effectively address symptoms and prevent the full-blown onset of mental disorders in refugees and asylum seekers.
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- 2021
40. Risk factors for mental disorder development in asylum seekers and refugees resettled in Western Europe and Turkey: Participant-level analysis of two large prevention studies.
- Author
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Barbui C, Tedeschi F, Acarturk C, Anttila M, Au T, Baumgartner J, Carswell K, Churchill R, Cuijpers P, Karyotaki E, Klein T, Koesters M, Lantta T, Nosè M, Ostuzzi G, Pasquini M, Prina E, Sijbrandij M, Tarsitani L, Turrini G, Uygun E, Välimäki M, Walker L, Wancata J, White RG, and Purgato M
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- Humans, Turkey epidemiology, Europe epidemiology, Risk Factors, Refugees psychology, Stress Disorders, Post-Traumatic epidemiology, Stress Disorders, Post-Traumatic psychology
- Abstract
Background: In asylum seekers and refugees, the frequency of mental disorders, such as depression, anxiety and post-traumatic stress disorder, is higher than the general population, but there is a lack of data on risk factors for the development of mental disorders in this population., Aim: This study investigated the risk factors for mental disorder development in a large group of asylum seekers and refugees resettled in high- and middle-income settings., Methods: Participant-level data from two randomized prevention studies involving asylum seekers and refugees resettled in Western European countries and in Turkey were pooled. The two studies randomized participants with psychological distress, but without a diagnosis of mental disorder, to the Self-Help Plus psychological intervention or enhanced care as usual. At baseline, exposure to potentially traumatic events was measured using the Harvard Trauma Questionnaire-part I, while psychological distress and depressive symptoms were assessed with the General Health Questionnaire and the Patient Health Questionnaire. After 3 and 6 months of follow-up, the proportion of participants who developed a mental disorder was calculated using the Mini International Neuropsychiatric Interview., Results: A total of 1,101 participants were included in the analysis. At 3- and 6-month follow-up the observed frequency of mental disorders was 13.51% (115/851) and 24.30% (207/852), respectively, while the frequency estimates after missing data imputation were 13.95% and 23.78%, respectively. After controlling for confounders, logistic regression analysis showed that participants with a lower education level ( p = .034), a shorter duration of journey ( p = .057) and arriving from countries with war-related contexts ( p = .017), were more at risk of developing mental disorders. Psychological distress ( p = .004), depression ( p = .001) and exposure to potentially traumatic events ( p = .020) were predictors of mental disorder development., Conclusions: This study identified several risk factors for the development of mental disorders in asylum seekers and refugees, some of which may be the target of risk reduction policies. The identification of asylum seekers and refugees at increased risk of mental disorders should guide the implementation of focused preventative psychological interventions.
- Published
- 2023
- Full Text
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