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13 results on '"Attala, Letizia"'

1. Clinical features and comorbidity pattern of HCV infected migrants compared to native patients in care in Italy: A real-life evaluation of the PITER cohort

Author

Mazzaro, Cesare, Bertola, Manuela, Schioppa, Ornella, Benedetti, Antonio, Schiadà, Laura, Cucco, Monica, Giacometti, Andrea, Brescini, Laura, Castelletti, Sefora, Fiorentini, Alessandro, Angarano, Gioacchino, Milella, Michele, Di Leo, Alfredo, Rendina, Maria, D'abramo, Fulvio Salvatore, Lillo, Chiara, Iannone, Andrea, Piazzolla, Mariano, Verucchi, Gabriella, Badia, Lorenzo, Piscaglia, Fabio, Benevento, Francesca, Serio, Ilaria, Castelli, Francesco, Zaltron, Serena, Spinetti, Angiola, Odolini, Silvia, Bruno, Raffaele, Mondelli, Mario, Chessa, Luchino, Loi, Martina, Torti, Carlo, Costa, Chiara, Mazzitelli, Maria, Pisani, Vincenzo, Scaglione, Vincenzo, Trecarichi, Enrico Maria, Zignego, Anna Linda, Monti, Monica, Madia, Francesco, Blanc, Pier Luigi, Attala, Letizia, Pierotti, Piera, Salomoni, Elena, Mariabelli, Elisa, Santantonio, Teresa Antonia, Bruno, Serena Rita, Cela, Ester Marina, Bassetti, Matteo, Mazzarello, Giovanni, Alessandrini, Anna Ida, Di Biagio, Antonio, Nicolini, Laura Ambra, Raimondo, Giovanni, Filomia, Roberto, Aghemo, Alessio, Meli, Rossella, Lazzarin, Adriano, Morsica, Giulia, Salpietro, Stefania, Galli, Massimo, Fracanzani, Anna Ludovica, Fatta, Erika, Lombardi, Rosa, Lampertico, Pietro, Borghi, Marta, D'ambrosio, Roberta, Degasperi, Elisabetta, Puoti, Massimo, Baiguera, Chiara, D'amico, Federico, Vinci, Maria, Rumi, Maria Grazia, Zuin, Massimo, Giorgini, Alessia, Zermiani, Paola, Andreone, Pietro, Caraceni, Paolo, Margotti, Marzia, Guarneri, Valeria, Villa, Erica, Bernabucci, Veronica, Bristot, Laura, Paradiso, Maria Luisa, Migliorino, Guglielmo, Beretta, Ilaria, Gambaro, Alessandra, Lapadula, Giuseppe, Spolti, Anna, Soria, Alessandro, Invernizzi, Pietro, Ciaccio, Antonio, LucÀ, Martina, Malinverno, Federica, Ratti, Laura, Coppola, Carmine, Amoruso, Daniela Caterina, Pisano, Federica, Scarano, Ferdinando, Staiano, Laura, Morisco, Filomena, Cossiga, Valentina, Gentile, Ivan, Buonomo, Antonio Riccardo, Foggia, Maria, Zappulo, Emanuela, Federico, Alessandro, Dallio, Marcello, Coppola, Nicola, Sagnelli, Caterina, Martini, Salvatore, Monari, Caterina, Nardone, Gerardo, Sgamato, Costantino, Chemello, Liliana, Cavalletto, Luisa, Sterrantino, Daniela, Russo, Francesco Paolo, Zanetto, Alberto, Zanaga, Paola, Barbaro, Francesco, Brancaccio, Giuseppina, Craxì, Antonio, Petta, Salvatore, Calvaruso, Vincenza, Crapanzano, Luciano, Madonia, Salvatore, Cannizzaro, Marco, Bruno, Erica Maria, Licata, Anna, Amodeo, Simona, Capitano, Adele Rosaria, Ferrari, Carlo, Laccabue, Diletta, Negri, Elisa, Orlandini, Alessandra, Pesci, Marco, Gulminetti, Roberto, Pagnucco, Layla, Parruti, Giustino, Di Stefano, Paola, Brunetto, Maurizia Rossana, Coco, Barbara, Massari, Marco, Corsini, Romina, Garlassi, Elisa, Andreoni, Massimo, Teti, Elisabetta, Cerva, Carlotta, Baiocchi, Lorenzo, Tata, Xhimi, Grassi, Giuseppe, Gasbarrini, Antonio, Pompili, Maurizio, De Siena, Martina, Taliani, Gloria, Biliotti, Elisa, Spaziante, Martina, Persico, Marcello, Masarone, Mario, Aglitti, Andrea, Calvanese, Gemma, Anselmo, Marco, De Leo, Pasqualina, Marturano, Monica, Saracco, Giorgio Maria, Ciancio, Alessia, Ieluzzi, Donatella, Quaranta, Maria Giovanna, Ferrigno, Luigina, D'Angelo, Franca, Saracino, Annalisa, and Kondili, Loeta A.

Published
2021
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4. Real-life safety of Emtricitabine/Tenofovir Alafenamide/Bictegravir

Author

Squillace, N, Ricci, E, Maggi, P, Taramasso, L, Menzaghi, B, De Socio, G, Piconi, S, Maurizio Celesia, B, Orofino, G, Sarchi, E, Pellicanò, G, Simeone, F, Valsecchi, L, Bandera, A, Cenderello, G, Attala, L, Angioni, G, Falasca, K, Cascio, A, Bargiacchi, O, Di Biagio, A, Bonfanti, P, Squillace, Nicola, Ricci, Elena, Maggi, Paolo, Taramasso, Lucia, Menzaghi, Barbara, De Socio, Giuseppe Vittorio, Piconi, Stefania, Maurizio Celesia, Benedetto, Orofino, Giancarlo, Sarchi, Eleonora, Pellicanò, Giovanni Francesco, Simeone, Filomena, Valsecchi, Laura, Bandera, Alessandra, Cenderello, Giovanni, Attala, Letizia, Angioni, Goffredo, Falasca, Katia, Cascio, Antonio, Bargiacchi, Olivia, Di Biagio, Antonio, Bonfanti, Paolo, Squillace, N, Ricci, E, Maggi, P, Taramasso, L, Menzaghi, B, De Socio, G, Piconi, S, Maurizio Celesia, B, Orofino, G, Sarchi, E, Pellicanò, G, Simeone, F, Valsecchi, L, Bandera, A, Cenderello, G, Attala, L, Angioni, G, Falasca, K, Cascio, A, Bargiacchi, O, Di Biagio, A, Bonfanti, P, Squillace, Nicola, Ricci, Elena, Maggi, Paolo, Taramasso, Lucia, Menzaghi, Barbara, De Socio, Giuseppe Vittorio, Piconi, Stefania, Maurizio Celesia, Benedetto, Orofino, Giancarlo, Sarchi, Eleonora, Pellicanò, Giovanni Francesco, Simeone, Filomena, Valsecchi, Laura, Bandera, Alessandra, Cenderello, Giovanni, Attala, Letizia, Angioni, Goffredo, Falasca, Katia, Cascio, Antonio, Bargiacchi, Olivia, Di Biagio, Antonio, and Bonfanti, Paolo

Abstract

Introduction Integrase strand transfer inhibitors (INSTI) are one of the most prescribed drug classes for the treatment of HIV infection worldwide. Emtricitabine/Tenofovir Alafenamide/ Bictegravir (FTC/TAF/BIC) has been evaluated in randomized clinical trials; few studies have verified tolerability and safety in clinical practice. Our aim was to investigate the metabolic and hepatic safety in a real-life setting of FTC/TAF/BIC. Materials and methods Consecutive people living with HIV infection (PLWH) enrolled in the SCOLTA project, switching to or initiating their first antiretroviral treatment with FTC/TAF/BIC were included. PLWH with HBV co-infection were excluded. Metabolic and hepatic variables were collected at T0 and T1, were defined as baseline and 6-month follow-up respectively, and their modifications were analysed using the paired t-test and the analysis of variance. Results Five hundred and thirty-nine PLWH with at least one follow-up visit were included in the analysis. Mean age was 48 years (±12.1), 74% were male, 16.1% were naïve to antiretrovirals (ART). At T1, ART-experienced PLWH showed a significant reduction of total cholesterol (TC) and triglycerides, and a slight increase in blood glucose (BG) and ALT. On the contrary, in ART-naïve PLWH blood lipids significantly increased, although with an unaffected TC/high density lipoprotein (HDL)-c ratio, while alanine aminotransferase (ALT) decreased significantly, mainly in those with altered baseline level. The treatment interruptions were 45 (8.4%) over the whole observation period, 13 (2.4%) due to AEs. The most frequent AEs were related to the central nervous system (6 events of depression, insomnia, headache, agitation) and 3 PLWH discontinued the regimen because of grade 1-2 weight gain. Conclusions In ART-experienced PLWH switching to FTC/TAF/BIC a significant improvement of lipid profile occurred but with significant BG and ALT variation without clinical relevance. In ARTnaïve PLWH, blood lipid

Published
2023

5. Real-life safety of Emtricitabine/Tenofovir Alafenamide/Bictegravir.

Author

Squillace, Nicola, Ricci, Elena, Maggi, Paolo, Taramasso, Lucia, Menzaghi, Barbara, De Socio, Giuseppe Vittorio, Piconi, Stefania, Maurizio Celesia, Benedetto, Orofino, Giancarlo, Sarchi, Eleonora, Pellicanò, Giovanni Francesco, Simeone, Filomena, Valsecchi, Laura, Bandera, Alessandra, Cenderello, Giovanni, Attala, Letizia, Angioni, Goffredo, Falasca, Katia, Cascio, Antonio, and Bargiacchi, Olivia

Subjects
TENOFOVIR, HIGH density lipoproteins, BLOOD lipids, EMTRICITABINE, HIV infections, ASPARTATE aminotransferase, ALANINE aminotransferase
Abstract

Introduction: Integrase strand transfer inhibitors (INSTI) are one of the most prescribed drug classes for the treatment of HIV infection worldwide. Emtricitabine/Tenofovir Alafenamide/ Bictegravir (FTC/TAF/BIC) has been evaluated in randomized clinical trials; few studies have verified tolerability and safety in clinical practice. Our aim was to investigate the metabolic and hepatic safety in a real-life setting of FTC/TAF/BIC. Materials and methods: Consecutive people living with HIV infection (PLWH) enrolled in the SCOLTA project, switching to or initiating their first antiretroviral treatment with FTC/TAF/BIC were included. PLWH with HBV co-infection were excluded. Metabolic and hepatic variables were collected at T0 and T1, were defined as baseline and 6-month follow-up respectively, and their modifications were analysed using the paired t-test and the analysis of variance. Results: Five hundred and thirty-nine PLWH with at least one follow-up visit were included in the analysis. Mean age was 48 years (±12.1), 74% were male, 16.1% were naïve to antiretrovirals (ART). At T1, ART-experienced PLWH showed a significant reduction of total cholesterol (TC) and triglycerides, and a slight increase in blood glucose (BG) and ALT. On the contrary, in ART-naïve PLWH blood lipids significantly increased, although with an unaffected TC/high density lipoprotein (HDL)-c ratio, while alanine aminotransferase (ALT) decreased significantly, mainly in those with altered baseline level. The treatment interruptions were 45 (8.4%) over the whole observation period, 13 (2.4%) due to AEs. The most frequent AEs were related to the central nervous system (6 events of depression, insomnia, headache, agitation) and 3 PLWH discontinued the regimen because of grade 1–2 weight gain. Conclusions: In ART-experienced PLWH switching to FTC/TAF/BIC a significant improvement of lipid profile occurred but with significant BG and ALT variation without clinical relevance. In ART-naïve PLWH, blood lipids increased even though lipid profile did not worsen, and a trend towards normalization of liver enzymes was suggested. FTC/TAF/BIC is well tolerated in the real life setting. [ABSTRACT FROM AUTHOR]

Published
2023
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8. Remdesivir treatment and transient bradycardia in patients with coronavirus diseases 2019 (COVID-19)

Author

Pallotto, Carlo, primary, Blanc, Pierluigi, additional, Esperti, Sara, additional, Suardi, Lorenzo Roberto, additional, Gabbuti, Andrea, additional, Vichi, Francesca, additional, Mecocci, Lorenzo, additional, Esposti, Anna Degli, additional, Pierotti, Piera, additional, Attala, Letizia, additional, Salomoni, Elena, additional, Baragli, Filippo, additional, Francisci, Daniela, additional, and Pietro, Massimo Antonio Di, additional

Published
2021
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11. Serial QuantiFERON TB-Gold in-tube testing during LTBI therapy in candidates for TNFi treatment

Author

Bartalesi, Filippo, primary, Goletti, Delia, additional, Spinicci, Michele, additional, Cavallo, Annalisa, additional, Attala, Letizia, additional, Mencarini, Jessica, additional, Fiori, Ginevra, additional, Li Gobbi, Francesca, additional, Mantella, Antonia, additional, Benucci, Maurizio, additional, Prignano, Francesca, additional, Pimpinelli, Nicola, additional, Matucci Cerinic, Marco, additional, Girardi, Enrico, additional, and Bartoloni, Alessandro, additional

Published
2013
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12. In Sight but out of Mind

Author

Attala, Letizia, primary, Tremblay, Adam, additional, Corti, Giampaolo, additional, Saint, Sanjay, additional, and Bartoloni, Alessandro, additional

Published
2013
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13. Latent tuberculosis infection in psoriasis and other dermatological immunomediated diseases: a combined approach by Quanti FERON®- TB Gold and tuberculin skin tests.

Author

Prignano, Francesca, Bartoloni, Alessandro, Bartalesi, Filippo, Gori, Alessia, Ricceri, Federica, Cavallo, Annalisa, Attala, Letizia, and Mantella, Antonia

Subjects
CD4 antigen, T cells, TUBERCULIN test, DERMATOLOGY, MYCOBACTERIUM tuberculosis
Abstract

The article offers information on the QuantiFERON-TB Gold (QFT-G) assay used to measure the release of interferon-gamma by peripheral CD4-positive T lymphocytes. Topics include the tuberculin skin test (TST) used to diagnose latent tuberculosis infection (LTBI), the role of TB screening in dermatological patients, and the effectiveness of QFT-G. It also mentions the reliability of the QFT-G as a diagnostic test for LTBI.

Published
2014
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