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1. Brain fractalkine-CX3CR1 signalling is anti-obesity system as anorexigenic and anti-inflammatory actions in diet-induced obese mice

2. The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice

3. Spinal Astrocyte-Neuron Lactate Shuttle Contributes to the Pituitary Adenylate Cyclase-Activating Polypeptide/PAC1 Receptor-Induced Nociceptive Behaviors in Mice

4. FFAR1/GPR40 Contributes to the Regulation of Striatal Monoamine Releases and Facilitation of Cocaine-Induced Locomotor Activity in Mice

5. The novel small-molecule antagonist of PAC1 receptor attenuates formalin-induced inflammatory pain behaviors in mice

6. Establishment of disseminated intravascular coagulation (DIC) model by a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of its pathophysiological status

7. GPR40/FFAR1 deficient mice increase noradrenaline levels in the brain and exhibit abnormal behavior

8. Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice

9. Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice.

10. The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice

11. Small-molecule non-peptide antagonists of the PACAP receptor attenuate acute restraint stress-induced anxiety-like behaviors in mice

12. The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory

13. The Pivotal Role of Neuropeptide Crosstalk from Ventromedial-PACAP to Dorsomedial-Galanin in the Appetite Regulation in the Mouse Hypothalamus

14. Chronic Royal Jelly Administration Induced Antidepressant-Like Effects Through Increased Sirtuin1 and Oxidative Phosphorylation Protein Expression in the Amygdala of Mice

15. Spinal astrocyte-neuron lactate shuttle contributes to the pituitary adenylate cyclase-activating polypeptide/PAC1 receptor-induced nociceptive behaviors in mice

16. The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory

17. Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist

27. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor

28. Establishment of disseminated intravascular coagulation (DIC) model by a single iv administration of Escherichia coli -derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of its pathophysiological status

29. The Deletion of GPR40/FFAR1 Signaling Damages Maternal Care and Emotional Function in Female Mice

30. Pituitary Adenylate Cyclase-Activating Polypeptide in the Ventromedial Hypothalamus Is Responsible for Food Intake Behavior by Modulating the Expression of Agouti-Related Peptide in Mice

33. Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice

35. Synthesis of a novel and potent small-molecule antagonist of PAC1 receptor for the treatment of neuropathic pain

36. Do intrathecal PACAP-evoked aversive behaviors represent itch-like behaviors ? - Possible involvement of PACAP signaling system in spinal itch transmission in mice

40. [Astrocyte-neuron lactate shuttle, the major effector of astrocytic PACAP signaling for CNS functions]

41. Spinal astrocyte-neuron lactate shuttle contributes to the PACAP/PAC1 receptor-induced nociceptive behaviors

42. Potential Involvement of Mitochondrial Dysfunction in Major Depressive Disorder: Recent Evidence

43. Involvement of free fatty acid receptor GPR40/FFAR1 in the regulation of spinal nociceptive transmission

45. Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice

46. C-Type Natriuretic Peptide Modulates Permeability of the Blood–Brain Barrier

47. Development and pharmacological verification of a new mouse model of central post-stroke pain

49. DHA ameliorates repeated stress induced-chronic pain via GPR40/FFAR1

50. A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells

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