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Byline: Shrikant. Atreya Life-threatening bleeding although uncommon in palliative care is associated with significant distress among patients and family. The current guidelines emphasize the need for identification of a patient [...]

Byline: Shrikant. Atreya, Gaurav. Kumar, Jyotiprakash. Samal, Moitri. Bhattacharya, Shabnam. Banerjee, Pallab. Mallick, Debratna. Chakraborty, Sunipa. Gupta, Saswati. Sarkar Introduction: Novel coronavirus disease 2019 (COVID 19) has usurped human peace [...]

Byline: Shrikant. Atreya Introduction: Patients with advanced gynecological malignancies often present with a high burden of symptoms endangering their quality of life. Objective: This study aims at assessing the symptom [...]

Byline: Shrikant. Atreya Cancer-related fatigue (CRF) is one of the most common problems facing patients both during and after completion of treatment. Overall 50%-90% of cancer patients experience fatigue the [...]

Byline: Jayita. Deodhar, Vanita. Noronha, Mary. Muckaden, Shrikant. Atreya, Amit. Joshi, Sandeep. Tandon, Arunangshu. Ghoshal, Naveen. Salins, Vijay. Patil, Kumar. Prabhash Purpose: Early palliative care is beneficial in advanced lung [...]

Byline: Shrikant. Atreya Chemotherapeutic agents belonging to vinca alkaloids, taxanes, and antitubulins produce peripheral neuropathy for which there is no validated treatment. Pregabalin, a gamma-aminobutyric acid analog, is known to [...]

Byline: Shrikant. Atreya, Gaurav. Kumar, Soumitra. Datta Vagal sensory neuropathy or vagal hypersensitivity has been implicated in the pathophysiology of chronic cough. Earlier reports have shown gabapentin to be effective [...]

Paralysis of hypoglossal nerve is rare and often underreported. The paralysis leads to the deviation of tongue, dysarthria, dysphagia, and airway dysfunction, affecting the quality of life. We report a case of a middle-aged woman with malignancy of unknown origin with bone and brain metastasis who presented with unilateral deviation of the tongue. Detailed workup inferred with metastasis to the clivus bone which is related to the hypoglossal canal at the base of the skull and the primary origin could not be established. Intravenous steroids, radiotherapy, and systemic chemotherapy were helpful in improvement of the nerve palsy in our patient. Hypoglossal nerve palsy is often an underrated and underreported lesion; however, it can be a starting point for a major underlying problem. [ABSTRACT FROM AUTHOR]

Objectives: Inadequate access to cancer care, high mortality, and out-of-pocket expenditure contribute to health-related suffering in low- and middle-income countries, making palliative care a relevant option. How palliative care development has alleviated suffering is not systematically studied, necessitating this review's conduct. The objective of this systematic review with a framework synthesis approach is to identify and map the dimensions and indicators of cancer palliative care development and the components of integration between cancer and palliative care in LMICs., Methods: Uni- and multi-disciplinary databases like Cochrane, MEDLINE (PubMed), EMBASE, CINAHL Complete, and PsycINFO will be systematically searched for eligible studies exploring cancer palliative care development in LMICs and their contribution to alleviating health-related suffering in the cancer context. Our selection process will encompass countries classified by the World Bank as low-income (26 countries), lower-income (54 countries), and upper-middle-income (54 countries)., Results: Review findings will be synthesised and analysed using a best-fit framework synthesis method using 2 frameworks (the WHO model of components and indicators for palliative care development and integration elements between oncology and palliative care), and the findings will be developed as themes and subthemes, and patterns interpreted using these 2 models., Significance of Results: This review will analyse the development of cancer palliative care in LMICs. It will identify gaps in provision, solutions derived at the regional level to address them, and best practices and failed models with reasons underpinning them.