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331 results on '"Ateeq, Bushra"'

27. Data from Identification of Targetable FGFR Gene Fusions in Diverse Cancers

Author

Wu, Yi-Mi, primary, Su, Fengyun, primary, Kalyana-Sundaram, Shanker, primary, Khazanov, Nickolay, primary, Ateeq, Bushra, primary, Cao, Xuhong, primary, Lonigro, Robert J., primary, Vats, Pankaj, primary, Wang, Rui, primary, Lin, Su-Fang, primary, Cheng, Ann-Joy, primary, Kunju, Lakshmi P., primary, Siddiqui, Javed, primary, Tomlins, Scott A., primary, Wyngaard, Peter, primary, Sadis, Seth, primary, Roychowdhury, Sameek, primary, Hussain, Maha H., primary, Feng, Felix Y., primary, Zalupski, Mark M., primary, Talpaz, Moshe, primary, Pienta, Kenneth J., primary, Rhodes, Daniel R., primary, Robinson, Dan R., primary, and Chinnaiyan, Arul M., primary

Published
2023
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28. Data from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Author

Wang, Xiao-Song, primary, Shankar, Sunita, primary, Dhanasekaran, Saravana M., primary, Ateeq, Bushra, primary, Sasaki, Atsuo T., primary, Jing, Xiaojun, primary, Robinson, Daniel, primary, Cao, Qi, primary, Prensner, John R., primary, Yocum, Anastasia K., primary, Wang, Rui, primary, Fries, Daniel F., primary, Han, Bo, primary, Asangani, Irfan A., primary, Cao, Xuhong, primary, Li, Yong, primary, Omenn, Gilbert S., primary, Pflueger, Dorothee, primary, Gopalan, Anuradha, primary, Reuter, Victor E., primary, Kahoud, Emily Rose, primary, Cantley, Lewis C., primary, Rubin, Mark A., primary, Palanisamy, Nallasivam, primary, Varambally, Sooryanarayana, primary, and Chinnaiyan, Arul M., primary

Published
2023
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29. Supplementary Methods and Data (posted 7/5/2011) from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Author

Wang, Xiao-Song, primary, Shankar, Sunita, primary, Dhanasekaran, Saravana M., primary, Ateeq, Bushra, primary, Sasaki, Atsuo T., primary, Jing, Xiaojun, primary, Robinson, Daniel, primary, Cao, Qi, primary, Prensner, John R., primary, Yocum, Anastasia K., primary, Wang, Rui, primary, Fries, Daniel F., primary, Han, Bo, primary, Asangani, Irfan A., primary, Cao, Xuhong, primary, Li, Yong, primary, Omenn, Gilbert S., primary, Pflueger, Dorothee, primary, Gopalan, Anuradha, primary, Reuter, Victor E., primary, Kahoud, Emily Rose, primary, Cantley, Lewis C., primary, Rubin, Mark A., primary, Palanisamy, Nallasivam, primary, Varambally, Sooryanarayana, primary, and Chinnaiyan, Arul M., primary

Published
2023
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30. Supplementary Figures from Identification of Targetable FGFR Gene Fusions in Diverse Cancers

Author

Wu, Yi-Mi, primary, Su, Fengyun, primary, Kalyana-Sundaram, Shanker, primary, Khazanov, Nickolay, primary, Ateeq, Bushra, primary, Cao, Xuhong, primary, Lonigro, Robert J., primary, Vats, Pankaj, primary, Wang, Rui, primary, Lin, Su-Fang, primary, Cheng, Ann-Joy, primary, Kunju, Lakshmi P., primary, Siddiqui, Javed, primary, Tomlins, Scott A., primary, Wyngaard, Peter, primary, Sadis, Seth, primary, Roychowdhury, Sameek, primary, Hussain, Maha H., primary, Feng, Felix Y., primary, Zalupski, Mark M., primary, Talpaz, Moshe, primary, Pienta, Kenneth J., primary, Rhodes, Daniel R., primary, Robinson, Dan R., primary, and Chinnaiyan, Arul M., primary

Published
2023
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31. Supplementary Tables from Identification of Targetable FGFR Gene Fusions in Diverse Cancers

Author

Wu, Yi-Mi, primary, Su, Fengyun, primary, Kalyana-Sundaram, Shanker, primary, Khazanov, Nickolay, primary, Ateeq, Bushra, primary, Cao, Xuhong, primary, Lonigro, Robert J., primary, Vats, Pankaj, primary, Wang, Rui, primary, Lin, Su-Fang, primary, Cheng, Ann-Joy, primary, Kunju, Lakshmi P., primary, Siddiqui, Javed, primary, Tomlins, Scott A., primary, Wyngaard, Peter, primary, Sadis, Seth, primary, Roychowdhury, Sameek, primary, Hussain, Maha H., primary, Feng, Felix Y., primary, Zalupski, Mark M., primary, Talpaz, Moshe, primary, Pienta, Kenneth J., primary, Rhodes, Daniel R., primary, Robinson, Dan R., primary, and Chinnaiyan, Arul M., primary

Published
2023
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33. Supplementary Methods, Figures, Tables, and References from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Author

Wang, Xiao-Song, primary, Shankar, Sunita, primary, Dhanasekaran, Saravana M., primary, Ateeq, Bushra, primary, Sasaki, Atsuo T., primary, Jing, Xiaojun, primary, Robinson, Daniel, primary, Cao, Qi, primary, Prensner, John R., primary, Yocum, Anastasia K., primary, Wang, Rui, primary, Fries, Daniel F., primary, Han, Bo, primary, Asangani, Irfan A., primary, Cao, Xuhong, primary, Li, Yong, primary, Omenn, Gilbert S., primary, Pflueger, Dorothee, primary, Gopalan, Anuradha, primary, Reuter, Victor E., primary, Kahoud, Emily Rose, primary, Cantley, Lewis C., primary, Rubin, Mark A., primary, Palanisamy, Nallasivam, primary, Varambally, Sooryanarayana, primary, and Chinnaiyan, Arul M., primary

Published
2023
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43. Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer

Author

Wang, Xiaoju, Qiao, Yuanyuan, Asangani, Irfan A., Ateeq, Bushra, Poliakov, Anton, Cieślik, Marcin, Pitchiaya, Sethuramasundaram, Chakravarthi, Balabhadrapatruni V.S.K., Cao, Xuhong, Jing, Xiaojun, Wang, Cynthia X., Apel, Ingrid J., Wang, Rui, Ching-Yi Tien, Jean, Juckette, Kristin M., Yan, Wei, Jiang, Hui, Wang, Shaomeng, Varambally, Sooryanarayana, and Chinnaiyan, Arul M.

Published
2024
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44. The Role of Sarcosine Metabolism in Prostate Cancer Progression

Author

Amjad P Khan, Thekkelnaycke M Rajendiran, Ateeq Bushra, Irfan A Asangani, Jyoti N Athanikar, Anastasia K Yocum, Rohit Mehra, Javed Siddiqui, Ganesh Palapattu, John T Wei, George Michailidis, Arun Sreekumar, and Arul M Chinnaiyan

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Metabolomic profiling of prostate cancer (PCa) progression identified markedly elevated levels of sarcosine (N-methyl glycine) in metastatic PCa and modest but significant elevation of the metabolite in PCa urine. Here, we examine the role of key enzymes associated with sarcosine metabolism in PCa progression. Consistent with our earlier report, sarcosine levels were significantly elevated in PCa urine sediments compared to controls, with a modest area under the receiver operating characteristic curve of 0.71. In addition, the expression of sarcosine biosynthetic enzyme, glycine N-methyltransferase (GNMT), was elevated in PCa tissues, while sarcosine dehydrogenase (SARDH) and pipecolic acid oxidase (PIPOX), which metabolize sarcosine, were reduced in prostate tumors. Consistent with this, GNMT promoted the oncogenic potential of prostate cells by facilitating sarcosine production, while SARDH and PIPOX reduced the oncogenic potential of prostate cells by metabolizing sarcosine. Accordingly, addition of sarcosine, but not glycine or alanine, induced invasion and intravasation in an in vivo PCa model. In contrast, GNMT knockdown or SARDH overexpression in PCa xenografts inhibited tumor growth. Taken together, these studies substantiate the role of sarcosine in PCa progression.

Published
2013
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48. Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

Author

Varambally, Sooryanarayana, Cao, Qi, Mani, Ram-Shankar, Shankar, Sunita, Wang, Xiaosong, Ateeq, Bushra, Laxman, Bharathi, Cao, Xuhong, Jing, Xiaojun, Ramnarayanan, Kalpana, Brenner, J. Chad, Yu, Jindan, Kim, Jung H., Han, Bo, Tan, Patrick, Kumar-Sinha, Chandan, Lonigro, Robert J., Palanisamy, Nallasivam, Maher, Christopher A., and Chinnaiyan, Arul M.

Published
2008
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49. Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer

Author

Cao, Qi, Mani, Ram-Shankar, Ateeq, Bushra, Dhanasekaran, Saravana M., Asangani, Irfan A., Prensner, John R., Kim, Jung H., Brenner, J. Chad, Jing, Xiaojun, Cao, Xuhong, Wang, Rui, Li, Yong, Dahiya, Arun, Wang, Lei, Pandhi, Mithil, Lonigro, Robert J., Wu, Yi-Mi, Tomlins, Scott A., Palanisamy, Nallasivam, Qin, Zhaohui, Yu, Jindan, Maher, Christopher A., Varambally, Sooryanarayana, and Chinnaiyan, Arul M.

Published
2011
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50. Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

Author

Brenner, J. Chad, Ateeq, Bushra, Li, Yong, Yocum, Anastasia K., Cao, Qi, Asangani, Irfan A., Patel, Sonam, Wang, Xiaoju, Liang, Hallie, Yu, Jindan, Palanisamy, Nallasivam, Siddiqui, Javed, Yan, Wei, Cao, Xuhong, Mehra, Rohit, Sabolch, Aaron, Basrur, Venkatesha, Lonigro, Robert J., Yang, Jun, Tomlins, Scott A., Maher, Christopher A., Elenitoba-Johnson, Kojo S.J., Hussain, Maha, Navone, Nora M., Pienta, Kenneth J., Varambally, Sooryanarayana, Feng, Felix Y., and Chinnaiyan, Arul M.

Published
2011
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