483 results on '"Asokan, Aravind"'
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2. Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing
3. A humanized mouse model for adeno-associated viral gene therapy
4. An evolved AAV variant enables efficient genetic engineering of murine T cells
5. Engineering Synthetic circRNAs for Efficient CNS Expression
6. Progressive liver disease and dysregulated glycogen metabolism in murine GSD IX γ2 models human disease
7. Structure-guided AAV capsid evolution strategies for enhanced CNS gene delivery
8. Engineered IgM and IgG cleaving enzymes for mitigating antibody neutralization and complement activation in AAV gene transfer
9. Gene delivery followed by ex vivo lung perfusion using an adeno-associated viral vector in a rodent lung transplant model
10. Capsid-mediated control of adeno-associated viral transcription determines host range
11. Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer
12. The NIH Somatic Cell Genome Editing program
13. Redirecting AAV vectors to extrahepatic tissues
14. Adeno-associated virus mediates gene transduction after static cold storage treatment in rodent lung transplantation
15. Multi-apical polarity of alveolar stem cells and their dynamics during lung development and regeneration
16. Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion
17. Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing
18. Evaluation of Aav Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy
19. Deep Learning Resolves Myovascular Dynamics in the Failing Human Heart
20. Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy
21. Systemic and Persistent Muscle Gene Expression in Rhesus Monkeys with a Liver De-Targeted Adeno-Associated Virus Vector
22. Transgenic mice for in vivo epigenome editing with CRISPR-based systems
23. Engineering highly efficient backsplicing and translation of synthetic circRNAs
24. Gene Delivery From Granular Scaffolds for Tunable Biologics Manufacturing.
25. Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing
26. Abstract TMP3: Overexpression of Alk1 in Brain Endothelial Cells Alleviates the Severity of Brain Arteriovenous Malformations in Alk1 Mutant Mice
27. Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus
28. An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses.
29. The membrane associated accessory protein is an adeno-associated viral egress factor
30. Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.
31. AAV vector immunotoxicity: Stopping the domino effect
32. Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion
33. Efficient Adeno-associated Virus–mediated Transgenesis in Alveolar Stem Cells and Associated Niches
34. Gene delivery followed by ex vivo lung perfusion using an adeno-associated viral vector in a rodent lung transplant model
35. AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model
36. Viral gene delivery platform evolution
37. Gene Therapy of CNS Disorders Using Recombinant AAV Vectors
38. AAV9-mediated gene delivery to liver grafts during static cold storage in a rat liver transplant model
39. Single-Pilot Aircraft in Commercial Air Transport Operations: A Comparison of Potential Architectures
40. Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry
41. Rescue of glutaric aciduria type I in mice by liver-directed therapies
42. Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies
43. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
44. RESCUE OF GLUTARIC ACIDURIA TYPE I MICE BY LIVER DIRECTED THERAPIES
45. An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair
46. P173: Establishing preclinical efficacy for the first AAV gene therapy for GSD IX γ2 across stages of progressive liver disease
47. CRISPR genome editing in stem cells turns to gold
48. Synthetic ribonucleoprotein granules regulate translation of a target mRNA in living cells
49. Adeno-associated virus mediates gene transduction after static cold storage treatment in rodent lung transplantation
50. Gene Therapy: Will the Promise of Optimizing Lung Allografts Become Reality?
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