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3. Comparative evaluation of biomechanical changes and aberration profile following accelerated collagen cross-linking using hypo-osmolar and iso-osmolar riboflavin: A prospective study

Author

Manumuraleekrishna, Asif, Mohamed Ibrahime, Maharana, Prafulla Kumar, Nagpal, Ritu, Agarwal, Tushar, Sinha, Rajesh, Titiyal, Jeewan Singh, and Sharma, Namrata

Subjects
Medical research -- Analysis, Medicine, Experimental -- Analysis, Biomechanics -- Analysis, Collagen -- Analysis, Health
Abstract

Purpose: To compare the changes encountered in corneal biomechanics and aberration profile following accelerated corneal collagen cross-linking (CXL) using hypo-osmolar and iso-osmolar riboflavin in corneal thicknesses of 400 microns, respectively. Methods: This is a prospective, interventional, comparative study involving 100 eyes of 75 patients with progressive keratoconus. Eyes were divided into two groups based on corneal thickness: group 1 included eyes with a corneal thickness of 400 microns who underwent iso-osmolar CXL. Corneal biomechanical and aberration profiles were evaluated and compared between groups. Results: In group 1, all higher-order aberrations (HOA) except secondary astigmatism significantly decreased from baseline; however, in group 2, only coma and trefoil decreased. The corneal resistance factor and corneal hysteresis significantly improved in both groups, which was significantly greater in group 2 than in group 1. The change in inverse radius, deformation amplitude, and tomographic biomechanical index was significantly improved in group 2 as compared to group 1. Conclusion: Improvement in corrected distance visual acuity and decrease in HOA were significantly better in the hypo-osmolar CXL group; however, the improvement in biomechanical strength of the cornea was significantly better in the iso-osmolar group. Keywords: Accelerated collagen cross-linking, corneal biomechanics, higher-order aberration, hypo-osmolar riboflavin, iso-osmolar riboflavin, keratoconus, Author(s): Manumuraleekrishna [1]; Mohamed Ibrahime Asif [1]; Prafulla Kumar Maharana [1]; Ritu Nagpal [1]; Tushar Agarwal [1]; Rajesh Sinha [1]; Jeewan Singh Titiyal [1]; Namrata Sharma (corresponding author) [1] Introduction [...]

Published
2024
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4. Assertive community treatment for high-utilizing alcohol misuse patients: a before-and-after cohort study protocol

Author

Juntian Wu, Fahad Javaid Siddiqui, Charles Chia Meng Mak, Ivan Si Yong Chua, Jeevan Raaj Thangayah, Esther Xi Xiang Tan, Huey Ying Seet, Adriel Kailing Rao, Hann Yee Tan, Asif Mohamed, Mikael Hartman, Benjamin Sieu-Hon Leong, Marcus Eng Hock Ong, and Desmond Renhao Mao

Subjects
Alcohol-related frequent attenders, Emergency department utilization, Assertive community treatment, Healthcare resource optimization, Singapore, Public aspects of medicine, RA1-1270
Abstract

Abstract Background The challenge posed by Alcohol-Related Frequent Attenders (ARFAs) in Emergency Departments (EDs) is growing in Singapore, marked by limited engagement with conventional addiction treatment pathways. Recognizing this gap, this study aims to explore the potential benefits of Assertive Community Treatment (ACT) - an innovative, community-centered, harm-reduction strategy—in mitigating the frequency of ED visits, curbing Emergency Medical Services (EMS) calls, and uplifting health outcomes across a quartet of Singaporean healthcare institutions. Methods Employing a prospective before-and-after cohort design, this investigation targeted ARFAs aged 21 years and above, fluent in English or Mandarin. Eligibility was determined by a history of at least five ED visits in the preceding year, with no fewer than two due to alcohol-related issues. The study contrasted health outcomes of patients integrated into the ACT care model versus their experiences under the exclusive provision of standard emergency care across Hospitals A, B, C and D. Following participants for half a year post-initial assessment, the evaluation metrics encompassed socio-demographic factors, ED, and EMS engagement frequencies, along with validated health assessment tools, namely Christo Inventory for Substance-misuse Services (CISS) scores, University of California, Los Angeles (UCLA) Loneliness scores, and Centre for Epidemiologic Studies Depression Scale Revised (CESD-R-10) scores. Discussion Confronted with intricate socio-economic and medical challenges, the ARFA cohort often grapples with heightened vulnerabilities in relation to alcohol misuse. Pioneering the exploration of ACT’s efficacy with ARFAs in a Singaporean context, our research is anchored in a patient-centered approach, designed to comprehensively address these multifaceted clinical profiles. While challenges, like potential high attrition rates and sporadic data collection, are anticipated, the model’s prospective contribution towards enhancing patient well-being and driving healthcare efficiencies in Singapore is substantial. Our findings have the potential to reshape healthcare strategies and policy recommendations. Trial Registration ClinicalTrials.gov, NCT 04447079. Initiated on 25 June 2020.

Published
2024
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5. Management of acute corneal hydrops - Current perspectives

Author

Bafna, Rahul, Kalra, Nidhi, Asif, Mohamed, Beniwal, Abhijeet, Lata, Suman, Sharma, Sumant, Agarwal, Rinky, Vanathi, Murugesan, Maharana, Prafulla, Titiyal, Jeewan, and Sharma, Namrata

Subjects
Corneal diseases -- Care and treatment -- Causes of -- Diagnosis, Dropsy -- Care and treatment -- Causes of -- Diagnosis, Edema -- Care and treatment -- Causes of -- Diagnosis, Health
Abstract

Byline: Rahul. Bafna, Nidhi. Kalra, Mohamed. Asif, Abhijeet. Beniwal, Suman. Lata, Sumant. Sharma, Rinky. Agarwal, Murugesan. Vanathi, Prafulla. Maharana, Jeewan. Titiyal, Namrata. Sharma Acute corneal hydrops (ACH) is a rare [...]

Published
2024

6. A rare case of paraneoplastic Guillain-Barré syndrome in a patient with endometrial cancer

Author

Asif Mohamed Farook, Dilshan Priyankara, Chamali Aluwihare, and Anthony Mendis

Subjects
guillain-barré syndrome, paraneoplastic, endometrial carcinoma, Medicine
Abstract

Introduction: Guillain-Barré syndrome is an acute, inflammatory polyradiculoneuropathy of autoimmune aetiology. It is a rare disease seen in 1 in 100,000 person-years. Up to 20% of those affected develop severe disability; mortality in Guillain-Barré syndrome is 5%. Guillain-Barré, associated with many malignancies as a paraneoplastic phenomenon, has been reported – especially in haematological malignancies such as lymphoma and leukaemia. Solid tumours associated with paraneoplastic Guillain-Barré syndrome are breast and lung cancers. The association between paraneoplastic Guillain-Barré syndrome and gynaecological malignancies are rare, and only a handful of cases have been previously reported in gynaecological cancers. Case description: We discuss a 65-year-old Sri Lankan female patient diagnosed with metastatic endometrial carcinoma who presented with paraneoplastic Guillain-Barré syndrome. The patient was treated appropriately and eventually recovered from her condition. Conclusion: Paraneoplastic Guillain-Barré syndrome is a rare phenomenon that clinicians can easily miss, and it has rarely been described in gynaecological cancers. Our patient was diagnosed with this rare phenomenon. The timely recognition and prompt treatment of this potentially life-threatening condition with multiple complications is essential in managing patients with malignancies and neuropathy. Further studies on paraneoplastic Guillain-Barré syndrome are needed as cases may be underreported.

Published
2023
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7. Peripheral ulcerative keratitis in a child - An unusual presentation

Author

Gaur, Sandhya, Yadav, Mrinalini, Singh, Deependra, and Asif, Mohamed

Subjects
Collagen, Keratitis, Health
Abstract

Byline: Sandhya. Gaur, Mrinalini. Yadav, Deependra. Singh, Mohamed. Asif Peripheral ulcerative keratitis (PUK) is an inflammatory disorder of the cornea characterized by crescent-shaped destructive inflammation of the juxtalimbal corneal stroma [...]

Published
2023

8. Management and prevention of corneal graft rejection

Author

Mandal, Sohini, Maharana, Prafulla, Kaweri, Luci, Asif, Mohamed, Nagpal, Ritu, and Sharma, Namrata

Subjects
Graft rejection -- Prevention, Eye -- Surgery, Health
Abstract

Byline: Sohini. Mandal, Prafulla. Maharana, Luci. Kaweri, Mohamed. Asif, Ritu. Nagpal, Namrata. Sharma The management of an episode of corneal graft rejection (CGR) is primarily by corticosteroids. Immunomodulators are useful [...]

Published
2023

9. Atypical viral keratitis in a graft

Author

Beniwal, Abhijeet, Bafna, Rahul, Rani, Deeksha, and Asif, Mohamed

Subjects
Antiviral agents -- Dosage and administration, Cornea -- Transplantation, Keratitis -- Risk factors -- Diagnosis -- Care and treatment, Health
Abstract

Byline: Abhijeet. Beniwal, Rahul. Bafna, Deeksha. Rani, Mohamed. Asif A 70-year-old male patient, a known case of rheumatoid arthritis, presented with multiple elevated atypical vesicular corneal lesions admixed with an [...]

Published
2023

10. Connective tissue disorders and eye: A review and recent updates

Author

Asif, Mohamed, Kalra, Nidhi, Sharma, Namrata, Jain, Neha, Sharma, Mohita, and Sinha, Rajesh

Subjects
Eye diseases -- Diagnosis -- Care and treatment, Connective tissue diseases -- Diagnosis -- Care and treatment, Autoimmune diseases -- Diagnosis -- Care and treatment, Health
Abstract

Byline: Mohamed. Asif, Nidhi. Kalra, Namrata. Sharma, Neha. Jain, Mohita. Sharma, Rajesh. Sinha Collagen vascular disorders (CVDs), also known as connective tissue diseases (CTDs), are a heterogeneous group of entities [...]

Published
2023

12. Immunopathogenesis of corneal graft rejection

Author

Maharana, Prafulla, Mandal, Sohini, Kaweri, Luci, Sahay, Pranita, Lata, Suman, Asif, Mohamed, Nagpal, Ritu, and Sharma, Namrata

Subjects
Immunopathology -- Analysis, B cells -- Analysis, Cornea -- Transplantation, Graft rejection -- Risk factors -- Prevention, Health
Abstract

Byline: Prafulla. Maharana, Sohini. Mandal, Luci. Kaweri, Pranita. Sahay, Suman. Lata, Mohamed. Asif, Ritu. Nagpal, Namrata. Sharma The most common cause of corneal graft failure is corneal graft rejection (CGR). [...]

Published
2023

14. A review of techniques and outcomes of endothelial keratoplasty in congenital hereditary endothelial dystrophy

Author

Mandal, Sohini, Asif, Mohamed, Maharana, Prafulla, Sharma, Namrata, and Titiyal, Jeewan

Subjects
Corneal diseases -- Care and treatment -- Patient outcomes, Cornea -- Transplantation, Health
Abstract

Byline: Sohini. Mandal, Mohamed. Asif, Prafulla. Maharana, Namrata. Sharma, Jeewan. Titiyal Congenital hereditary endothelial dystrophy affects the Descemet membrane and endothelium, resulting in corneal decompensation. Penetrating keratoplasty (PKP) has been [...]

Published
2022

17. Deep Learning Techniques for Early Detection of Autism Spectrum Disorder - Systematic Study

Author

null Asif Mohamed H B, null Dr. Md. Sameeruddin Khan, null Dr. Mohan K G, and null Dr. Parashuram Baraki

Subjects
General Medicine
Abstract

This paper narrates the various categories of image classification techniques. Image classification is an important tool for extracting information from digital images. The purpose of this research article is to summarize information on several image classification techniques.

Published
2023

18. Machine Learning based Feature Selection Approaches for Early Prediction of Autism Spectrum Disorder - Review

Author

null Asif Mohamed H B, null Dr. Md. Sameeruddin Khan, null Dr. Mohan K G, and null Dr. Parashuram Baraki

Subjects
General Medicine
Abstract

Feature selection is the task of selecting a small subset of the original features that can achieve maximum classification accuracy. This subset of features has some very important benefits: This makes feature selection an essential task for classification tasks.

Published
2023

19. Road to universal health coverage: unique model of Karnataka, India

Author

S., Pooja, primary, Shastri, Suresh G., additional, P. K., Srinivas, additional, G. D., Gagana, additional, J., Murugesh, additional, N., Shivashankara, additional, C., Sudha, additional, Ichini, Sushil Kumar, additional, Asif, Mohamed, additional, M. R., Sangeetha, additional, and D., Randeep, additional

Published
2023
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20. Acute psychosis after refractive surgery

Author

Asif, Mohamed, Meena, Suman, Titiyal, Jeewan, and Kaur, Manpreet

Subjects
Laser in situ keratomileusis -- Case studies -- Complications and side effects, Vision disorders -- Case studies -- Complications and side effects -- Care and treatment, Psychoses -- Case studies -- Development and progression -- Care and treatment, Health
Abstract

Byline: Mohamed. Asif, Suman. Meena, Jeewan. Titiyal, Manpreet. Kaur A 20-year-old male with no previous history of systemic or mental illness underwent femtosecond laser-assisted in situ keratomileusis (LASIK) in both [...]

Published
2022

22. Premium intraocular lenses in children

Author

Asif, Mohamed Ibrahime, primary, Raj, Nimmy, additional, Kalra, Nidhi, additional, Yadav, Mrinalini Anand, additional, Bafna, Rahul Kumar, additional, and Sinha, Rajesh, additional

Published
2022
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23. Posterior stromal crystalline keratopathy in gout

Author

Asif, Mohamed, Bafna, Rahul, Shaji, Kalathil, Yadav, Mrinalini, and Sinha, Rajesh

Subjects
Gout -- Diagnosis -- Complications and side effects, Eye diseases -- Diagnosis -- Care and treatment, Crystalline lens -- Health aspects, Health
Abstract

Byline: Mohamed. Asif, Rahul. Bafna, Kalathil. Shaji, Mrinalini. Yadav, Rajesh. Sinha A 55-year-old female presented with painless, diminution of vision in the right eye for 6 months. She had episodes [...]

Published
2021

24. Back-out method for removing a large lower eyelid foreign body

Author

Das, Deepsekhar, Asif, Mohamed, and Reddy, Divya

Subjects
Eyelid diseases -- Care and treatment -- Patient outcomes, Foreign bodies (Medical care) -- Health aspects, Health
Abstract

Byline: Deepsekhar. Das, Mohamed. Asif, Divya. Reddy Case Report A 13-year-old male presented to the ophthalmology emergency with an anchor-shaped keychain lodged in his right lower eyelid [Figure 1]a. He [...]

Published
2021

25. A case of old total Descemet membrane detachment due to ophthalmic viscosurgical device with clear cornea: Microscope-integrated intraoperative optical coherence tomography-guided drainage

Author

Kalra, Nidhi, Asif, Mohamed, Bhalla, Jatinder, Bafna, Rahul, and Sinha, Rajesh

Subjects
Drainage, Surgical -- Case studies, Cornea -- Injuries, Trabeculectomy -- Case studies -- Complications and side effects, CT imaging -- Case studies, Open-angle glaucoma -- Case studies -- Care and treatment, Health
Abstract

Byline: Nidhi. Kalra, Mohamed. Asif, Jatinder. Bhalla, Rahul. Bafna, Rajesh. Sinha We report a case of a large bullous descemet membrane detachment (DMD) following inadvertent injection of ophthalmic viscoelastic device [...]

Published
2021

26. A rare case of Haberland syndrome

Author

Asif, Mohamed, Goel, Siddhi, Yadav, Mrinalini, Singh, Vipul, and Maharana, Prafulla

Subjects
Children -- Diseases, Genetic disorders -- Case studies -- Diagnosis -- Care and treatment, Health
Abstract

Byline: Mohamed. Asif, Siddhi. Goel, Mrinalini. Yadav, Vipul. Singh, Prafulla. Maharana A 10-month-old male child presented with a mass lesion in the left eye which was present since birth as [...]

Published
2021

27. Intracameral fungal bridge

Author

Asif, Mohamed, Lata, Suman, Shristi, Bafna, Rahul, and Sinha, Rajesh

Subjects
Health
Abstract

Byline: Mohamed. Asif, Suman. Lata, . Shristi, Rahul. Bafna, Rajesh. Sinha A 17-year-old female, with a history of trauma with an unknown object while driving, presented with painless diminution of [...]

Published
2021

29. Complications of small incision lenticule extraction

Author

Asif, Mohamed, Bafna, Rahul, Mehta, Jodhbir, Reddy, Jagadesh, Titiyal, Jeewan, Maharana, Prafulla, and Sharma, Namrata

Subjects
Eye surgery -- Complications and side effects, Health risk assessment -- Evaluation, Medical research, Health
Abstract

Byline: Mohamed. Asif, Rahul. Bafna, Jodhbir. Mehta, Jagadesh. Reddy, Jeewan. Titiyal, Prafulla. Maharana, Namrata. Sharma The procedure of small incision lenticule extraction (SMILE) was introduced in 2011, and since then [...]

Published
2020

31. Use of 'U-shaped tool for follow up of corneal ulcer cases in the COVID-19 pandemic

Author

Bafna, Rahul, Beniwal, Abhijeet, Kalra, Nidhi, Lata, Suman, Asif, Mohamed, and Sharma, Namrata

Subjects
Telemedicine -- Methods, Epidemics -- Influence -- India, Corneal diseases -- Diagnosis -- Care and treatment, COVID-19 -- Influence, Smart phones -- Usage, Smart phone, Health
Abstract

Byline: Rahul. Bafna, Abhijeet. Beniwal, Nidhi. Kalra, Suman. Lata, Mohamed. Asif, Namrata. Sharma To describe a smartphone-based telemedicine tool for monitoring of corneal ulcer size during the corona pandemic, a [...]

Published
2020

32. Clinical profile and prevalence of conjunctivitis in mild COVID-19 patients in a tertiary care COVID-19 hospital: A retrospective cross-sectional study

Author

Sindhuja, K., Lomi, Neiwete, Asif, Mohamed, and Tandon, Radhika

Subjects
Ophthalmic research -- Physiological aspects, Conjunctivitis -- Diagnosis -- Care and treatment, COVID-19 -- Physiological aspects -- Care and treatment -- Diagnosis, Health
Abstract

Byline: K. Sindhuja, Neiwete. Lomi, Mohamed. Asif, Radhika. Tandon Purpose: To find the clinical profile and prevalence of conjunctivitis and other ocular manifestations in mild COVID-19 positive patients in a [...]

Published
2020

36. Hitch suture assisted tuck in Tenon's Patch Graft for management of Corneal Perforations

Author

Bafna, Rahul Kumar, primary, Kalra, Nidhi, additional, Rathod, Aishwarya, additional, Asif, Mohamed Ibrahime, additional, Lata, Suman, additional, Parmanand, Kumar, additional, Kaur, Navpreet, additional, Kittur, Amogh Shreekant, additional, Shakkarwal, Chetan, additional, Roop, Prakhyat, additional, Agarwal, Rinky, additional, Agarwal, Tushar, additional, and Sharma, Namrata, additional

Published
2022
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42. Double arcus cornealis

Author

Asif, Mohamed, Nayak, Shreya, Pujari, Amar, Sharma, Namrata, and Agarwal, Tushar

Subjects
Corneal diseases -- Diagnosis -- Physiological aspects, Cataracts, Surgery, Eye surgery, Cataract extraction, Health
Abstract

Byline: Mohamed. Asif, Shreya. Nayak, Amar. Pujari, Namrata. Sharma, Tushar. Agarwal A 70-year-old male patient presented with gradual, progressive diminution of vision involving both the eyes. On examination, his best [...]

Published
2019

43. Optimal refinement of residents' surgical skills by training on induced goat's eye corneoscleral perforation

Author

Pujari, Amar, Sharma, Namrata, Chaniyara, Manthan, Urkude, Jayanand, Singh, Rashmi, Yadav, Saumya, Mukhija, Ritika, Asif, Mohamed, and Sidhu, Navneet

Subjects
Eye injuries -- Care and treatment -- Research, Eye surgery -- Study and teaching, Residents (Medicine) -- Practice -- Training, Goats, Physicians, Health
Abstract

Byline: Amar. Pujari, Namrata. Sharma, Manthan. Chaniyara, Jayanand. Urkude, Rashmi. Singh, Saumya. Yadav, Ritika. Mukhija, Mohamed. Asif, Navneet. Sidhu Surgical skill enhancement for the residents under training can be performed [...]

Published
2019

44. Early Detection Of Autism Spectrum Disorder Using Enhanced Deep-Convolutional Neural Network (EdCnn) Models.

Author

H. B., Asif Mohamed, Sameeruddin Khan, Md., and K. G., Mohan

Abstract

Autism spectrum disorder (ASD), a type of mental condition, can be recognised using social media data and biological images. The neurological ailment known as autism spectrum disorder (ASD) is connected to brain development and has an aesthetic impact on the face. teenagers who The facial landmarks of children with ASD are markedly different from those of children who are typically developing (TD). This proposed research work built on a deep learning system, specifically a convolutional neural network with transfer learning and the flask framework. The classification challenge used the models Xception, Visual Geometry Group Network (VGG19), and NASNETMobile. [ABSTRACT FROM AUTHOR]

Published
2022
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47. Microscope Integrated Optical Coherence Tomography Guided Descemet Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy

Author

Asif, Mohamed Ibrahime, primary, Bafna, Rahul Kumar, additional, Sharma, Namrata, additional, Kaginalkar, Ananya, additional, Sinha, Rajesh, additional, Agarwal, Tushar, additional, Maharana, Prafulla Kumar, additional, Kaur, Manpreet, additional, Taank, Priya, additional, and Titiyal, Jeewan S, additional

Published
2021
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49. Microscope Integrated Optical Coherence Tomography Guided Descemet Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy

Author

Asif,Mohamed Ibrahime, Bafna,Rahul Kumar, Sharma,Namrata, Kaginalkar,Ananya, Sinha,Rajesh, Agarwal,Tushar, Maharana,Prafulla Kumar, Kaur,Manpreet, Taank,Priya, Titiyal,Jeewan S, Asif,Mohamed Ibrahime, Bafna,Rahul Kumar, Sharma,Namrata, Kaginalkar,Ananya, Sinha,Rajesh, Agarwal,Tushar, Maharana,Prafulla Kumar, Kaur,Manpreet, Taank,Priya, and Titiyal,Jeewan S

Abstract

Mohamed Ibrahime Asif,1 Rahul Kumar Bafna,1 Namrata Sharma,1 Ananya Kaginalkar,1 Rajesh Sinha,1 Tushar Agarwal,1 Prafulla Kumar Maharana,1 Manpreet Kaur,1 Priya Taank,2 Jeewan S Titiyal1 1Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India; 2Department of Ophthalmology, Command Hospital, Pune, 411040, IndiaCorrespondence: Namrata SharmaDepartment of Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, IndiaTel +91 9810856988Fax +91 11-26588919Email namrata.sharma@gmail.comPurpose: To describe the outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) in congenital hereditary endothelial dystrophy (CHED) and to evaluate the role of microscope integrated optical coherence tomography (Mi-OCT) during the surgery.Design: Retrospective data analysis.Methods: A retrospective study from the medical records of all those patients who were diagnosed with CHED and underwent DSAEK at our centre from 2015 were evaluated. All patients underwent Mi-OCT-guided standard DSAEK procedure. Intra-operative difficulties, visual outcomes and graft survival were recorded.Results: A total of 48 eyes of 29 patients with a mean age of 9.87 ± 8.2 years and mean follow-up of 17.3 months were evaluated. Thirty-nine eyes underwent primary DSAEK and 9 eyes underwent PKP. Three eyes who underwent PKP had failed graft for which they underwent DSAEK. The mean preoperative Snellen’s visual acuity was 1.71 ± 0.66 and the mean preoperative central corneal thickness was 1.10 ± 0.174 mm. Intraoperatively, all the grafts were attached which was confirmed using Mi-OCT. Graft detachment was seen in the immediate postoperative period in 10.4% (4 eyes) of primary DSAEK, out of which DM scoring was not performed in 2 eyes. Following DSAEK, cornea cleared at four-week follow-up in 89.7% eyes and in all the eyes the cornea cl

Published
2021

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