Intradialytic hypotension is the most common complication of haemodialysis (HD). This study on the effect of profiled hemodialysis on intradialytic hypotension(IDH) and related symptoms,nursing interventions during dialysis. Evaluated intradialytic hypotension related symptoms included muscle cramps, dizziness, headache,nausea and vomitting. Evaluated nursing interventions included saline infusion,decrease or stop ultrafiltration(UF) and session failure. In this study interdialytic weight and serum sodium concentration were evaluated also. This study included 24 patients on maintenance haemodialysis who experienced frequent episodes of intradialytic hypotension were recruited. There were 17 female and 7 male patients. There was significant improvement of IDH(p Key words : Intradialytic hypotesion, sodium profiles, ultrafiltration profiles. REFERENCES Abbas G, Rafiquee Z, Shafi T. Relationship of postdialysis serum sodium level and interdialytic weight gain in patients on maintenance hemodialysis. J Coll Physicians Surg Pak 2007; 17(8):482-5. Amine Mohamed Hamzi, Mohamed Asseraji, Kawtar Hassani , Ahmed Alayoud, Bahadi Abdellali,Yassir Zajjari, Dina Brahim Montacer, Ismail Akhmouch, Mohamed Benyahia, Zouhir Oualim: applying Sodium Profile with or without ultrafiltration Profile Failed to Show Beneficial Effects on the Incidence of Intradialytic Hypotension in Susceptible Hemodilaysis Patients. Arab Journal of Nephrology and Transplantation. 2012 Sep;5(3):129-34. Germin PD. Effect of automated blood volume control on the incidence of intra-dialysis hypotension. Acta Med Croatica 2003; 57(1):17-22. Henrich WL. Hemodynamic instability during hemodialysis: overview. Up To Date (version 15.3); Available from URL: http://www.uptodate.com. Kaczmarczyk I, Krasniak A, Drozdz M, Chowaniec E, Gajda M, Radziszewski A, et al. The influence of sodium profiling on blood volume and intradialytic hypotension in patients on maintenance hemodialysis. PrzeglLek 2007; 64(7-8):476-82. Mahdavimazdeh M, Hemmat AM, Ahmadi F, Seifi S. Comparison of acute clinical adverse effect and biocompatibility of poly sulfan and hemophanmembrances on intradialytic complications. Rah AvardeDanesh 2006; 9(4):88-92. Meira FS, PoliFigueiredo CE, Figueiredo AE. Influence of sodium profile in preventing complications during hemodialysis. HemodialInt 2007; 11(3):29-32. Moattari M, AzarHoshang P, Abbasian A, Raees JGH, Rajaee FA. The impact of cool dialysate on intradialytic hypotension in ESRD patients. Research in Medicine 2007; 67:31-72. Oliver MJ, Edwards LJ, Churchill DN. Impact of sodium and ultrafiltrationprofiling on hemodialysis-related symptoms. J Am Soc Nephrol 2001;12:151-6. Ramos R, Soto C, Mestres R, Jara J, Zequera H, Merello JI, et al. How can we improve symptomatic hypotension in hemodialysis patients: cold dialysis vsisothermic dialysis? Nefrologia 2007; 27(6):737-41. Santoro A, Mancini E, Basile C, Amoroso L, Di Giulio S, Usberti M, et al. Blood volume controlled hemodialysis in hypotension-prone patients: a randomized, multicenter controlled trial. Kidney Int 2002; 62(3):1034-45. Song JH, Park GH, Lee SY, Lee SW, Lee SW, Kim MJ. Effect of sodium balance and the combination of ultrafiltration profile during sodium profiling hemodialysis on the maintenance of the quality of dialysis and sodium and fluidbalances. J Am SocNephrol 2005; 16(1):237-46. Tang HL, Wong SH, Chu KH, Lee W, Cheuk A, Tang CM, et al. Sodium ramping reduces hypotension and symptoms during haemodialysis. Hong Kong Med J 2006; 12(1):10-4. YadavarNikravesh N. Assessing the frequency of infections resulted from vascular access in chronic hemodialysis patients hospitalized and their hospitalization costs in Al-Zahra Hospital; 2003-2004. [Thesis]. Isfahan: Isfahan University of Medical Sciences 2005. Zhou YL, Liu HL, Duan XF, Yao Y, Sun Y, Liu Q. Impact of sodium and ultrafiltration profiling on haemodialysis related hypotension. Nephrol Dial Transplant 2006; 21(11):3231-7.