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A field investigation was conducted during two kharif seasons of 2020-21 and 2021-2022 at Agriculture Research Farm, Rabindranath Tagore University, Raisen, Madhya Pradesh, India, to evaluate the effect of different irrigation scheduling and nutrient management practices on yield and economics of wheat crop in split-plot design with three replications. The irrigation level N0 - No irrigation, N1- One Irrigation at CRI (crown root inition) stage, N2- One Irrigation at CRI & one irrigation before flowering were arranged in main plots whereas nutrient management treatments of N0 – Control, N1-100% RDF + FYM @ 2.5 t/ha. + Azotobacter, N2 - 100% RDF + Vermicompost @ 1.5 t/ha + PSB, N3 - 50% RDF+ FYM@5.0 t/ha, N4 -50% RDF+ Vermicompost@2.5 t/ha were used in the sub plots. The results shown that one Irrigation at CRI & one irrigation before flowering along with application of 50% RDF+ FYM@5.0 t/ha found to be best in the terms of grain and straw yield 28.70 and 41.88 q ha-1 in 2021 and 29.52 q ha-1, 42.13 q ha-1 in 2022. Minimum yield and cost benefit ratio recorded under control plot. The study suggests economically combinations of currently used irrigation scheduling and nutrient management practices that may help farmer to obtaining optimum yield.

Background: The purpose of this study was to assess the accuracy of preoperative CT imaging for predicting pathologic nodal ECE (pECE). To estimate the accuracy of the presence of radiologic extranoda AIM: l extension (rENE) in reference to pathologic extranodal extension (pENE) in patients with oral cavity squamous cell carcinoma (OSCC) MATERIALS AND METHODS: This is a prospective study in GSVM Medical College, LLR & Associated Hospitals, Kanpur (UP). The records of 50 consecutive patients with oral cavity cancer (OCC) who underwent preoperative CT imaging before initial surgical resection and neck dissection between 2020 and 2021 were reviewed. Specimens with pECE had the extent of ECE graded on a scale from 1 to 4. Radiographic ECE was RESULTS: documented in 6 patients (12%), and pECE was observed in 11 (22%). Sensitivity, specicity, positive predictive value (PPV), and negative predictive value (NPV) were 45.4%, 97.4%, 83.6%, and 86.3%, respectively. The sensitivity of radio- graphic ECE increased from 40% for grade 1 to 2 ECE, to 50% for grade 3, and 50% for grade 4. Radiographic ECE criteria of adjacent structure invasion was a better predictor than irregular borders/fat stranding for pECE. Radiographic ECE has poor sensitivity, but excellent spec CONCLUSION: icity for pECE in patients who undergo initial surgical resection. PPV and NPV are reasonable for clinical decision making. The performance of preoperative CT imaging increased as pECE grade increased.

In the present scenario, microplastics (MPs) are emitted into the environment either directly from the use of cosmetic products or indirectly from the decomposition of big plastic items. These are commonly found in aquatic environments and amongst the most serious threats to freshwater ecosystems. Plastic components are broken down into the small fragments from large fragments during the treatment procedure in treatment plants of wastewater. Such plants act as an entry point for the MPs into the aquatic ecosystem; so it is necessary that MPs must be removed from the wastewater during the treatment process. Microplastics can be consumed directly by fish or indirectly through prey that contains these particles. These MPs can have a variety of ecotoxicological consequences on fish, including behavioural changes, cytotoxicity, neurotoxicity, and liver stress, among other things. The presence of microplastics along with the contaminants can boost the deposition of such contaminants in aquatic biota. Since the microplastics are of emerging concern, hence authors attempted to explain the possible impacts of these particles on aquatic species and human beings.

The aim of this study was to determine the effects of early-life bovine lactoferrin and host specific probiotic interventions on growth performance, mortality, and concentrations of immunoglobulin A and immunoglobulin G and transforming growth factor beta 1 (a marker of intestinal integrity) in serum of neonatal piglets. A total of eight piglet litters from parity matched sows were randomly divided into four groups and assigned to one of the four interventions: control (sterile normal saline), bovine lactoferrin (100 mg bovine lactoferrin), probiotic (1 × 10

The present investigation was designed to study the effect of sublethal concentration of paper mill effluent on the total protein and amino acid contents in muscles, liver and gill of Channa punctatus after exposure to 96 hours. A significant decrease in protein content with increase in amino acids content in muscles, liver and gill of effluent exposed fishes was observed. A reduction in the protein content and enhancement of free amino acids in the muscles, liver and gill of experimental fish suggests that the tissue protein might have undergone proteolysis, during the stressful situation. Thus, the present study concludes that the protein metabolism of fish Channa punctatus affected during effluent exposure and reduces the nutritive value of fish.

Sawan Nallah is a small lotic water body of Balrampur, U.P., India, which received semi treated effluents of sugar factory and distillery as well as municipal / domestic waste. The aim of the present investigation was to evaluate the toxic impact of these industrial and domestic wastes on water quality of Sawan nallaha and its toxic effect on fish population inhabiting it. The industrial effluent discharged in it caused significant changes in water quality that altered the haematological parameters (RBCs, WBCs, Hb% and PCV) and serum biochemical parameters (protein, free amino acids, glucose and triglycerides). The physico-chemical parameters of water were much higher than the tolerance limit recommended by Central Pollution Control Board of India.

The Indian Sarus crane (Grus antigone antigone) is a monogamous, graceful water bird, well known as an eternal symbol of unconditional love, devotion and good fortune with a high degree of marital fidelity. Its occurrence represents a healthy wetland ecosystem. A systematic study was conducted from June 2019 to May 2020 in the villages adjoining the Alwara Lake of district Kaushambi (Uttar Pradesh), India to explore the nesting behavior and current threats to the Sarus crane. During the study, a total number of 43 nests were encountered in the study area. The nests were seen on large wetlands, uplands, paddy fields, scattered irrigation ditches, adjoining areas of Lake etc. around the human settlements. These birds preferred to use local flora in constructing the nests, many of them with medicinal values. The main threats include the egg destruction by predator animals and indirect anthropogenic activities; however farmers tolerate the cranes nesting in their productive sites, despite the considerable crop damage.

Water pollution is a major problem in modern life. Almost all the heavy metals are toxic at higher concentrations and some are lethal at very low concentration. Arsenic is a naturally occurring element present in water, food and soil, but now-a-days this element is one of the rapidly emerging serious environmental pollutants; released into the environment through industrial and agricultural usage. In many parts of India, the ground water is contaminated with arsenic. The genesis of arsenic pollution is not understood fully, yet it is thought that natural geological weathering is mostly responsible for the dissolved arsenic in ground water. Arsenic exposure to human causes degenerative, inflammatory and neoplastic changes in skin, respiratory system, blood, lymphatic system, nervous system and reproductive system. There is no particular remedial action for chronic arsenic poisoning. Nearly 100 million people are to be affected by arsenic diseases like spots on the skin, high blood pressure, diabetes, skin cancer, cancer of urinary bladder, kidney and lungs. Low socio-economic status and malnutrition may increase the risk of chronic toxicity. There is a strong relationship between chronic ingestion of arsenic and deleterious human health effects. Safe drinking water and well-nourished food is essential for the prevention of chronic arsenic toxicity. Balance nutritious-supplements play a major role in the prevention of chronic arsenic poisoning. In this review article, authors tried to provide an overview of some of the major effects documented in the scientific literature.

Solid waste management, which is already a mammoth task in India, is becoming more complicated by the invasion of e-waste, particularly computer waste. The hazardous content of these e-waste materials pose a threat to human health and environment. This article highlights the hazards of e-wastes, the need for its appropriate management and options that can be implemented. Improper disposal of these e-wastes and other substances reach the soil and groundwater. Most of the e-waste materials can be reused, or recycled in an environmentally sound manner so that they are less harmful to the ecosystem.

The present study was undertaken to record the diversity of Balapur pond of the Prayagraj district of Uttar Pradesh with special reference to vertebrates and angiosperms. The Balapur pond was surveyed in detail once in a month for a period of one year from January 2018 to December 2018. The survey reflects a rich and flourishing biodiversity of the pond studied including 40 chordate species and 38 species of angiosperms. The notable chordate diversity includes 12 species of fishes, 2 species of amphibians, 7 species of reptiles, 11 species of birds and 8 species of mammals. Besides, several species of annelids, crabs, butterflies, moths, grasshoppers, ants, termites, lobsters, snails, other gastropods, planktons, algae, bryophytes and pteridophytes have also been observed.

The present investigation has been designed to study the effect of sub-lethal concentrations (10% and 30%) of heavy metal, arsenic on the serum metabolites, serum enzyme activity and serum electrolytes of Mystus vittatus after exposure to 30 days. The present study shows that serum metabolites such as glucose, protein and bilirubin were significantly decreased while free amino acid, triglyceride and cholesterol were significantly increased; serum enzymes such as acid phosphatase (ACP), transminases (SGPT & SGOT) were increased significantly while alkaline phosphatase (ALP), was decreased significantly; serum electrolytes such as sodium, potassium and calcium were decreased significantly but chloride was increased significantly. Thus, this paper gives an overview of the manipulation of fish, Mystus vittatus as a biomarker of heavy metals through alternation in biochemical parameters.

Biological classification is the scientific procedure of arranging the organisms in a hierarchical series of groups and sub-groups on the basis of their similarities and dissimilarities. Many biologists have contributed to this method of classification, which took years for researchers to decide the most fundamental characteristics for the classification. The history of kingdom system in classification is started with Linnaeus (1735), who laid the foundation of modern biological classification by classifying the organisms into two kingdoms namely Plantae and Animalia. The two kingdom system was followed by three, four, five and six kingdom systems respectively. In present discussion, authors tried to discuss the current status of different animal phyla with respect to different kingdom systems.

Introduction: India is experiencing an unprecedented rise in the number of breast cancer cases across all sections of society. Breast cancer is now the most common malignancy in women and the second leading cause of cancer- related mortality. Breast cancer is quite easily and effectively treated, provided it is detected in it's early stages. There is a drastic drop in the survival rates when women present with advanced stage of breast cancer, regardless of the setting. Unfortunately, women in resource-poor and developing countries, like India, generally present at a later stage of disease than women elsewhere, partly due to the absence of effective awareness programs and partly due to the lack of proper mass screening programs Aims And Objectives: The diagnostic performance of elastography in differentiating benign from malignant breast lesions. To assess whether elastography has the potential to reduce the need for breast biopsy /FNAC. Cut off value of Strain Ratio for benign versus malignant breast lesions. Further characterize BI-RADS 3 lesions using elastography Materials And Methods: The study was approved by the GSVM MEDICAL COLLEGE AND LLR HOSPITAL Ethics Committee. All patients that presented to the Radiology and Imaging Department of LLR HOSPITAL for diagnostic work up for breast pathology were included in the study. After obtaining a written and signed informed consent from all patients, they were subjected to conventional B-Mode ultrasonography followed by elastography. All diagnostic breast imaging was done with Samsung RS80A ultrasound machine using linear array transducer of frequency 5-12MHz.Observations & Results: The elastography patterns for each lesion were assessed and documented in color scale. Color images were constructed automatically and displayed as a color-overlay on the B-mode image. The color pattern of each lesion was then evaluated on a scale of 1-5 according to the Tsukuba elasticity scoring system. Conclusion: Strain Ratio cutoff of 3.3 is a sensitive parameter to differentiate benign and malignant breast lesions. Elastography is a specic test for differentiating benign and malignant breast lesions. The combined use of elasticity score, strain ratio and B- Mode sonographyincreases the diagnostic performance in distinguishing benign from malignant breast masses.

Introduction: Thyroid nodules are common and are commonly benign. The reported prevalence of nodular thyroid disease depends on the population studied and the methods used to detect nodules. Numerous studies suggest a prevalence of 2-6% with palpation, 19-35% with ultrasound, and 8-65% in autopsy data. Aims and objectives: To evaluate diagnostic reliability of ultrasound morphological criteria (ACR-TIRADS system) and elastographyin differentiating benign from malignant thyroid nodules in patients using cytopathology or histopathology as gold standard. Materials and methods: Prospective observational study, Patients visiting LLR (Hallet) Hospital with clinically suspicious thyroid nodule, LLR (Hallet) Hospital, GSVM Medical College, Jan 2019 to Oct 2020. Result: Showing distribution of composition of nodules in our study subjects Maximum nodules have mixed solid cystic composition . Showing distribution of echogenicity of nodules in our study subjects. Maximum nodules in our study have to hyperechoic echogenicity. Showing distribution of margin of nodules in our study subjects. Maximum nodules in our study have ill dened margin. Conclusion: In conclusion, no single investigation was found to be 100% sensitive or specic in diagnosing malignancy in nodular goiter but a good clinical, FNAC and USG examinations are complimentary to each other in predicting malignancy and avoid unnecessary or inadequate surgery.

The present study was conducted to evaluate the effect of rice bran crude lecithin (RBCL) on nutrient digestion and balance, performance, methanogenesis, blood and rumen profile. Eighteen crossbred calves were randomly divided into three groups; RBCL-0, RBCL-8 and RBCL-12 and fed wheat straw based diet with concentrate mixture containing 0, 8 and 12 % RBCL respectively. The dry matter, organic matter and crude protein intake were comparable but tended to decrease with the RBCL levels. The digestibility of dry matter, organic matter, total carbohydrate and gross energy tended to decrease while crude protein and ether extract digestibility tended to increase were with RBCL levels. The fibre fractions (NDF and ADF) digestibility was significantly (P 0.75) were significantly (P

The present investigation was undertaken to investigate the acute toxicity of cadmium, a heavy metal widely detected in the aquatic environment due to natural effects and anthropogenic activities, in freshwater teleost, Channa punctata (Bloch). The experiments for the bioassay were performed in semi-static test condition according to the standard guidelines. The behavioural changes in the fish were observed for all tested concentrations of the metal. The data obtained for bioassay were analyzed for median lethal concentrations (LC50) of the metal by SPSS computer software. The LC50 values, estimated by SPSS, with 95% confidence level were found to be:20.589 (18.326-23.221), 17.133 (14.840- 19.734), 11.815 (9.696 – 13.850) mg/L and 9.908 (7.635-12381) mg/L for cadmium chloride at 24, 48, 72 and 96 h exposure, respectively.

Catalytic thermolysis of petroleum refinery wastewater was investigated as a pretreatment process. Effects of various parameters like temperature, pH, dose of catalyst and time were investigated for chemical oxygen demand (COD), turbidity, and element reduction. CuSO4, FeSO4, FeCl3, and 1:1 ratio (v:v) mixture of CuSO4 and FeCl3 were used as a catalyst. The maximum reduction of COD and turbidity were 90 and 98% by mixture (1:1) of CuSO4 and FeCl3 at 70 °C, 7 pH, 1.0 kg/m3 dose in 90 min reaction time. The removal of an element like Cr, Mn, Ni, and Pb was analyzed by ICP-OES. The sludge precipitated after catalytic thermolysis was characterized using scanning electron microscopy with energy dispersive X-ray analysis (SEM-EDX), Fourier transform infrared (FTIR) and thermo-gravimetric analysis (TGA)/derivative thermal analysis (DTA) analyses. Sludge from CuSO4 and mixture of CuSO4 and FeCl3 treatment has a compact structure with irregular granule which favors adsorption.

An aorto-esophageal fistula (AEF) is a rare yet life-threatening cause of upper gastrointestinal bleeding. We report our experience with open surgical management of two cases of AEF. Both cases presented with almost identical presentations: hematemesis and hemodynamic instability. The aorta in the first patient was normal; the defect was small and was repaired with a Dacron patch. The second patient had an aneurysmal aorta, which was replaced with a Dacron graft. Both cases were performed under partial bypass. The esophageal rent in both patients was debrided, primarily closed and buttressed with a vascularized intercostal pedicle. Nonavailability of endovascular personnel and equipment along with hemodynamic instability of the patient influenced our surgical strategy. Long-term follow-up of these patients is necessary to analyze the outcomes of our surgical repair.

The Yarkovsky effect is a thermal process acting upon the orbits of small celestial bodies, which can cause these orbits to slowly expand or contract with time. The effect is subtle (da/dt ~ 10^-4 au/My for a 1 km diameter object) and is thus generally difficult to measure. We analyzed both optical and radar astrometry for 600 near-Earth asteroids (NEAs) for the purpose of detecting and quantifying the Yarkovsky effect. We present 247 NEAs with measured drift rates, which is the largest published set of Yarkovsky detections. This large sample size provides an opportunity to examine the Yarkovsky effect in a statistical manner. In particular, we describe two independent population-based tests that verify the measurement of Yarkovsky orbital drift. First, we provide observational confirmation for the Yarkovsky effect's theoretical size dependence of 1/D, where D is diameter. Second, we find that the observed ratio of negative to positive drift rates in our sample is 2.34, which, accounting for bias and sampling uncertainty, implies an actual ratio of $2.7^{+0.3}_{-0.7}$. This ratio has a vanishingly small probability of occurring due to chance or statistical noise. The observed ratio of retrograde to prograde rotators is two times lower than the ratio expected from numerical predictions from NEA population studies and traditional assumptions about the sense of rotation of NEAs originating from various main belt escape routes. We also examine the efficiency with which solar energy is converted into orbital energy and find a median efficiency in our sample of 12%. We interpret this efficiency in terms of NEA spin and thermal properties., Comment: 27 pages, 9 figures, published in the Astronomical Journal, 159, 92, 2020

Background: In hospitalized patients the use of intravenous devices like cannula are indispensable. Nearly about 80% of hospitalized patients require peripheral venous cannulation, as a part of therapy. Thrombophlebitis is one of the prevalent complications of peripheral venous cannulation.Method: The present study was aimed to find the incidence of thrombophlebitis after peripheral venous cannulations in the patients admitted in a tertiary care teaching hospital. Impact of regular trainings and interventions on the incidence and grades of thrombophlebitis was also studied. The study was conducted for period of 1 year.Result: The total of 28850 cannulations carried out on 11686 patients was observed. Phlebitis was diagnosed in 1821 peripheral venous cannulations, giving the incidence of 6.3%. As per Visual Infusion Phlebitis (VIP) score, 1527 (83.86%) were grade 1 phlebitis, 274 (15.04%) were with grade 2 phlebitis and 20 (1.10 %) were grade 3 phlebitis. Regular surveillance, training and timely interventions were carried out during this period and the effect of these interventions was noted in the monthly phlebitis rate. Phlebitis rate reduced from 9.89% in January to 3.99% in the month of December. There was also reduction in grade 2 thrombophlebitis (from 21.05% in January to 6.09% in December). In the last 4 months of study period grade 3 phlebitis was not reported.Conclusions: A significant reduction in the incidence of phlebitis associated with peripheral intravenous cannulations may be achieved by regular surveillance, training and timely interventions.

Background: Healthcare workers (HCWs) are at frontline of response of the current pandemic of the COVID-19. This exposes them to risk of infection due to insufficient knowledge and unhealthy practices. The aim of the study was to assess the knowledge of infection control practices among HCWs regarding COVID-19.Methods: A web-based cross-sectional survey was conducted between April 2020 and June 2020. A 21-questions survey was developed and distributed among study population. A total of 622 HCWs working in a dedicated COVID-19 hospital participated in this study. Descriptive statistics was applied to represent participant characteristics and Chi-square test was used to evaluate the level of association among variables with a significance level of

A process technology has been developed for recovery of naringin from kinnow (citrus) peels, which is a waste. The kinnow peels were boiled with water to extract naringin into water. It was adsorbed on an indigenous macroporous resin, Indion PA-500. Naringin was recovered from the saturated resin by desorption with ethanol as a solvent. The equilibrium and kinetic studies for both adsorption and desorption are presented. The Langmuir isotherm described the adsorption equilibrium data. However, desorption data were best described by the Toth isotherm. Adsorption and desorption kinetic data were found to follow a pseudo-second-order rate equation and second-order rate equation, respectively. Recovery of naringin was about 49% w/w (based on naringin present in peel-boiled extract). The purity of final products was 91–94% w/w.

Background: Despite the benefits of focused parathyroidectomy (FPTx), few studies have questioned its durability with lower long-term cure rates than bilateral or conventional parathyroidectomy (CPTx). The objective of this study is to bring out the information on the type of surgical management versus cure rate, recurrence, and role of intra-operative parathyroid hormone (IOPTH) level monitoring of PHPT patients. Material and Methods: This was a retrospective study of all PHPT patients treated at our center based on operative approach (CPTx vs FPTx) or use of IOPTH. Treatment failure was divided into persistent or recurrent disease, based on documentation of hypercalcemia in combination with an inappropriate PTH within 6 months or more of surgery, respectively. Results: Overall, 50.78% patients underwent CPTx and 49.32% FPTx. 29 FPTx were converted to CPTx. Intention to treat analysis between CPTx and FPTx showed that the persistence rate was not statistically different at 2.54% and 4%, respectively (P = 0.98). Furthermore, when the persistence rate was scrutinized by a treatment received (TR) instead of ITT analysis, the persistence rate was higher for the patients who underwent TR-CPTX than for the patients subjected to TR-FPTX (3.22% vs 1.08%) but not significant statistically. We further analyzed the outcome of FPTx with IOPTH (n = 213) and FPTx without IOPTH (n = 28). The outcome did not differ between two groups statistically. Conclusion: FPTx yields a similar success rate as compared to CPTx even in symptomatic PHPT patients and can be performed safely even without intra-opeartive adjunct IOPTH in selected patients.

Near-Earth asteroid (NEA) 1566 Icarus ($a=1.08$ au, $e=0.83$, $i=22.8^{\circ}$) made a close approach to Earth in June 2015 at 22 lunar distances (LD). Its detection during the 1968 approach (16 LD) was the first in the history of asteroid radar astronomy. A subsequent approach in 1996 (40 LD) did not yield radar images. We describe analyses of our 2015 radar observations of Icarus obtained at the Arecibo Observatory and the DSS-14 antenna at Goldstone. These data show that the asteroid is a moderately flattened spheroid with an equivalent diameter of 1.44 km with 18% uncertainties, resolving long-standing questions about the asteroid size. We also solve for Icarus' spin axis orientation ($\lambda=270^{\circ}\pm10^{\circ}, \beta=-81^{\circ}\pm10^{\circ}$), which is not consistent with the estimates based on the 1968 lightcurve observations. Icarus has a strongly specular scattering behavior, among the highest ever measured in asteroid radar observations, and a radar albedo of $\sim$2\%, among the lowest ever measured in asteroid radar observations. The low cross-section suggests a high-porosity surface, presumably related to Icarus' cratering, spin, and thermal histories. Finally, we present the first use of our orbit determination software for the generation of observational ephemerides, and we demonstrate its ability to determine subtle perturbations on NEA orbits by measuring Icarus' orbit-averaged drift in semi-major axis ($(-4.62\pm0.48) \times 10^{-4}$ au/My, or $\sim$60 m per revolution). Our Yarkovsky rate measurement resolves a discrepancy between two published rates that did not include the 2015 radar astrometry., Comment: 19 pages, 6 figures. The Astronomical Journal, in press