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3 results on '"Ashley, Ott"'

1. Arsenic toxicity manifesting as profuse watery diarrhea during induction therapy for acute promyelocytic leukemia

Author

Ashley Ott, Vinayak Venkataraman, Yousef R. Badran, Rose Goldman, Smiljana Spasic, Darshali A. Vyas, Philip Amrein, Steven McAfee, Andrew Brunner, Amir T. Fathi, and Rupa Narayan

Subjects
APL, APML, arsenic, diarrhea, obesity, renal insufficiency, Medicine, Medicine (General), R5-920
Abstract

Abstract Arsenic trioxide (ATO) is generally well tolerated for treatment of APL. We present a patient with severe watery diarrhea and pancreatitis thought to be due to ATO toxicity in the setting of obesity and acute kidney injury. Future studies evaluating ATO levels in patients experiencing toxicities may help guide dose modifications.

Published
2021
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3. Arsenic toxicity manifesting as profuse watery diarrhea during induction therapy for acute promyelocytic leukemia

Author

Darshali A. Vyas, Smiljana Spasic, Ashley Ott, Steven L. McAfee, Rose H. Goldman, Philip C. Amrein, Vinayak Venkataraman, Amir T. Fathi, Andrew M. Brunner, Yousef R. Badran, and Rupa Narayan

Subjects
Acute promyelocytic leukemia, medicine.medical_specialty, Medicine (General), obesity, diarrhea, Case Report, Case Reports, 030204 cardiovascular system & hematology, Gastroenterology, renal insufficiency, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, R5-920, Internal medicine, medicine, Arsenic trioxide, Arsenic toxicity, business.industry, Acute kidney injury, APML, arsenic, General Medicine, medicine.disease, APL, Diarrhea, chemistry, 030220 oncology & carcinogenesis, Toxicity, Pancreatitis, Medicine, medicine.symptom, Watery diarrhea, business
Abstract

Arsenic trioxide (ATO) is generally well tolerated for treatment of APL. We present a patient with severe watery diarrhea and pancreatitis thought to be due to ATO toxicity in the setting of obesity and acute kidney injury. Future studies evaluating ATO levels in patients experiencing toxicities may help guide dose modifications.

Published
2021

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