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Your search keyword '"Ashkenazim -- Research"' showing total 9 results
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9 results on '"Ashkenazim -- Research"'

1. Ashkenazi Jews and breast cancer: the consequences of linking ethnic identity to genetic disease

Author

Brandt-Rauf, Sherry I., Raveis, Victoria H., Drummond, Nathan F., Conte, Jill A., and Rothman, Sheila M.

Subjects
Ashkenazim -- Genetic aspects, Ashkenazim -- Research, Breast cancer -- Genetic aspects, Breast cancer -- Research, Ethnicity -- Risk factors, Ethnicity -- Research, Government, Health care industry
Abstract

We explored the advantages and disadvantages of using ethnic categories in genetic research. With the discovery that certain breast cancer gene mutations appeared to be more prevalent in Ashkenazi Jews, breast cancer researchers moved their focus from high-risk families to ethnicity. The concept of Ashkenazi Jews as genetically unique, a legacy of Tay-Sachs disease research and a particular reading of history, shaped this new approach even as methodological imprecision and new genetic and historical research challenged it. Our findings cast doubt on the accuracy and desirability of linking ethnic groups to genetic disease. Such linkages exaggerate genetic differences among ethnic groups and lead to unequal access to testing and therapy.

Published
2006

2. Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews

Author

Aharon-Peretz, Judith, Rosenbaum, Hanna, and Gershoni-Baruch, Ruth

Subjects
Hydrolases -- Research, Parkinson's disease -- Research, Parkinson's disease -- Care and treatment, Ashkenazim -- Research, Enzymes -- Research
Abstract

A study was conducted on 99 Ashkenazi Jews to find out whether mutations in the glucocerebrosidase (GBA) gene are relevant to idiopathic Parkinson's disease. Results suggest that heterozygosity for a GBA mutation may predispose Ashkenazi Jews to Parkinson's disease.

Published
2004

4. Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families

Author

Tukel, Turgut, Shalata, Adel, Present, Daniel, Rachmilewitz, Daniel, Mayer, Lloyd, Grant, Deniera, Risch, Neil, and Desnick, Robert J.

Subjects
Ashkenazim -- Research, Ashkenazim -- Genetic aspects, Ashkenazim -- Health aspects, Crohn's disease -- Research, Crohn's disease -- Genetic aspects, Sephardim -- Research, Sephardim -- Genetic aspects, Sephardim -- Health aspects, Biological sciences
Published
2004

5. Type 1 Gaucher disease: significant disease manifestations in 'asymptomatic' homozygotes

Author

Balwani, Manisha, Fuerstman, Laura, Kornreich, Ruth, Edelmann, Lisa, and Desnick, Robert J.

Subjects
Gaucher's disease -- Risk factors, Gaucher's disease -- Genetic aspects, Gaucher's disease -- Demographic aspects, Gaucher's disease -- Research, Homozygosity -- Demographic aspects, Homozygosity -- Research, Ashkenazim -- Genetic aspects, Ashkenazim -- Health aspects, Ashkenazim -- Research, Health
Published
2010

6. Cancer risks in carriers of the BRCA 1/2 Ashkenazi founder mutations

Author

Kadouri, Luna, Hubert, Ayala, Rotenberg, Yakir, Hamburger, Tamar, Sagi, Michal, Nechushtan, Chovav, Abeliovich, Dvorah, and Peretz, Tamar

Subjects
Breast cancer -- Risk factors, Breast cancer -- Genetic aspects, Ovarian cancer -- Risk factors, Ovarian cancer -- Genetic aspects, Ashkenazim -- Research, Ashkenazim -- Health aspects, Ashkenazim -- Genetic aspects, Health
Published
2007

7. Are Jews smarter?

Author

Senior, Jennifer

Subjects
Ashkenazim -- Research, Anthropologists -- Works
Published
2005

8. New Light On Origins Of Ashkenazi In Europe

Author

Wade, Nicholas

Subjects
Genetic research, Ashkenazim -- Research, Emigration and immigration -- Research
Abstract

A new look at the DNA of the Ashkenazi Jewish population has thrown light on its still mysterious origins. Until now, it had been widely assumed by geneticists that the […]

Published
2006

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