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1. Perceptions of the impact of individual allergic rhinitis symptoms: A survey of ARIA clinical experts

Author

Asllani, Julijana, Douagui, Habib, Asayag, Estrella, Elizabeth, Castro Maria, Crisci, Carlos D., Gomez, René Maximiliano, Ivancevich, Juan Carlos, Jares, Edgardo, Máspero, Jorge Fernando, Moreno, Pablo, Neffen, Hugo Eduardo, Zernotti, Mario Emilio, Bosnic-Anticevich, Sinthia, Chahhoud Carson, Kristin, Cvetkovski, Biljana, Davies, Janet M., Kritikos, Vicky, O'Hehir, Robyn, Oliver, Brian, Tan, House Rachel, Tattersall, Jessica, Zubrinich, Celia, Aberer, Werner, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Doyen, Virginie, Ebo, Didier, Louis, Renaud, Rombaux, Philippe, Scheire, Sophie, Bennoor, Kazi, Barreto, Bruno A., Camargos, Paulo, Chong-Neto, Herberto Jose, Cruz, Alvaro A., da Silva, Jane, Marta, Guidacci, Rizzo, José Angelo, Rosario Filho, Nelson, Faradiba, Sarquis Serpa, Solé, Dirceu, Urrutia-Pereira, Marilyn, Christoff, George, Mariana, Mandazhieva-Pepelanova, Cvetanka, Odjakova, Popov, Todor A., Vicheva, Dilyana, Teixeira Maria, do Ceu, Bouchard, Jacques, Brozek, Jan, Chu, Derek K., Denburg, Judah, Eiwegger, Thomas, Keith, Paul K., To, Teresa, Waserman, Susan, Abusada, Nancy, Alvarez Cuesta, Emilio, Calvo-Gil, Mario A., Guzmán, Maria Antonieta, Pérez Gomez, Tamara, Wong Gary, Wing Kin, Zhang, Luo, Caraballo, Luis, Cepeda Sarabia, Alfonso, Nyembue, Dieudonné, Soto-Martinez, Manuel, Miculinic, Neven, Plavec, Davor, Pitsios, Constantinos, Yiallouros, Panayiotis, Panzner, Petr, Sova, Milan, Vachova, Martina, Bindslev-Jensen, Carsten, Dahl, Ronald, Malling, Hans-Jorgen, Münter, Lars, Poulsen, Lars K., Charlotte, Suppli Ulrik, Tannert, Line Kring, Mahboub, Bassam, Salameh, Laila, Cherrez-Ojeda, Ivan, Robles, de Guevara Karla, El-Owaidy, Rasha Hassan, El-Sayed, Zeinab A., El-Sayed, Shereen Saad, Hossny, Elham, Mostafa, Badr Eldin, Julge, Kaja, Billo, Nils Eric, Eklund, Patrik, Erhola, Marina, Haahtela, Tari, Karjalainen, Jussi, Makela, Mika, Toppila-Salmi, Sanna, Valovirta, Erkka, Vasankari, Tuula, Annesi-Maesano, Isabella, Bossé, Isabelle, Bourgoin-Heck, Melisande, Charpin, Denis, Coste, André, de Blay, Frédéric, Devillier, Philippe, Didier, Alain, Dinh-Xuan, Anh Tuan, Fontaine, Jean-François, Just, Jocelyne, Nadif, Rachel, Pham-Thi, Nhân, Pigearias, Bernard, Roche, Nicolas, Ganse Eric, Van, Chkhartishvili, Ekaterine, Gamkrelidze, Amiran, Gotua, Maia, Becker, Sven, Bergmann, Karl-Christian, Bieber, Thomas, Brehler, Randolf, Buhl, Roland, Chaker, Adam M., Darsow, Ulf, Hamelmann, Eckard, Heinrich, Joachim, Keil, Thomas, Klimek, Ludger, Kolkhir, Pavel, Lau, Susanne, Maurer, Marcus, Mösges, Ralph, Neou, Angelos, Pfaar, Oliver, Ring, Johannes, Wagenmann, Martin, Zuberbier, Torsten, Ramanauskaite, Aiste, Lingnau, Anja, Christou, Demetrios, Neisinger, Sophia, Aggelidis, Xenophon, Constantinidis, Jannis, Dimou, Maria, Grigoreas, Christos, Kapsali, Trisevgeni, Katotomichelakis, Michael, Loukides, Stelios, Makris, Michael, Manousakis, Emmanouil, Mikos, Nikolaos, Pagkalos, Aris, Papadopoulos, Nikolaos G., Papanikolaou, Vasileios, Paraskevopoulos, Giannis, Piskou, Konstantina, Prokopakis, Emmanuel, Psarros, Fotios, Samitas, Konstantinos, Stamataki, Sofia, Stefanaki Lina, Evangelia, Syrigou, Ekaterini, Tsiligianni, Ioanna, Vallianatou, Mina, Vourdas, Dimitrios, Xepapadaki, Paraskevi, Karavelia, Aspasia, Wai San Ko, Fanny, Wong, Gary, Hirschberg, Andor, Kraxner, Helga, Nekam, Kristof, Lane, Stephen, Rottem, Menachem, Artesani Maria, Cristina, Barbaglia, Simona, Beghé, Bianca, Bilo Maria, Beatrice, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Braido, Fulvio, Brussino, Luisa, Canonica, G Walter, Cecchi, Lorenzo, Ciprandi, Giorgio, Compalati, Enrico, D'Amato, Gennaro, De Feo, Giulia, Del Giacco, Stefano, Fiocchi, Alessandro, Heffler, Enrico, Lombardi, Carlo, Monti, Riccardo, Muraro, Antonella, Nettis, Eustachio, Nicola, Stefania, Passalacqua, Giovanni, Patella, Vincenzo, Puggioni, Francesca, Rolla, Giovanni, Romano, Antonino, Scichilone, Nicola, Triggiani, Massimo, Ventura Maria, Teresa, Viegi, Giovanni, Boccabella, Cristina, Giovannini, Mattia, Mahesh Padukudru, Anand, Iinuma, Tomohisa, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimihiro, Pawankar, Ruby, Sakurai, Daiju, Suzukawa, Maho, Yamaguchi, Masao, Ispayeva, Zhanat, Chang, Yoon-Seok, Park, Hae-Sim, Al-Ahmad, Mona, Cirule, Ieva, Grisle, Ineta, Irani, Carla, Rouadi, Philip, Zaitoun, Fares, Dubakiene, Ruta, Emuzyte, Regina, Kvedariene, Violeta, Gradauskiene, Brigita, Valiulis, Arunas, Ollert, Markus, Hannachi, Farah, Dokic, Dejan, Abdul Latiff, Amir Hamzah, Abdullah, Baharudin, Palaniappan, S.P., Woo, Kent, Montefort, Stephen, Bedolla Barajas, Martín, Costa Domínguez, María del Carmen, Espinoza Contreras, Jesús Guillermo, Fuentes Pèrez, Jose Miguel, Gálvez Romero, José Luis, García Cruz, María de la Luz Hortensia, González Diaz, Sandra, Huerta Villalobos, Yunuen Rocío, Larenas-Linnemann, Désiree E., Luna-Pech, Jorge Agustin, Matta Campos, Juan José, Rivero Yeverino, Daniela, Rodríguez González, Mónica, Rodríguez Zagal, Eréndira, Lkhagvaa, Battur, Mavale-Manuel, Sandra, Nunes Elizabete, Abrantes, Chavannes, Niels, Fokkens, Wytske J., Koppelman, Gerard, Maitland-van der Zee, Anke-Hilse, Reitsma, Sietze, Chandrasekharan, Ramanathan, Yusuf, Osman, Repka-Ramirez, Maria Susana, Sisul, Juan Carlos, Gereda, José E., Recto, Marysia T., Bialek, Slawomir, Bialoszewski, Artur, Chelminska, Marta, Gawlik, Radoslaw, Jassem, Ewa, Jutel, Marek, Kuna, Piotr, Kupczyk, Maciej, Moniuszko, Marcin, Niedoszytko, Marek, Raciborski, Filip, Romantowski, Jan, Samolinski, Boleslaw, Specjalski, Krzysztof, Carreiro Martins, Pedro, Correia de Sousa, Jaime, Costa, Elisio, Fonseca, Joao A., Lourenço, Olga, Morais-Almeida, Mario, Pereira Ana, Margarida, Regateiro, Frederico, Robalo Cordeiro, Carlos, Rosado Pinto, Jose, Sousa-Pinto, Bernardo, Taborda Barata, Luis, Todo-Bom, Ana Maria, Vieira Rafael, José, Carvalho, Daniela, Al-Nesf, Maryam Ali, Agache, Ioana, Berghea Elena, Camelia, Bumbacea, Roxana, Deleanu, Diana, Mihaltan, Florin, Panaitescu Bunu, Carmen, Khaitov, Musa, Namazova-Baranova, Leyla, Vishneva, Elena, Alshaikh Nada, Ali, Dimic-Janjic, Sanja, Milenkovic, Branislava, Wang, De Yun, Hrubiško, Martin, Edelbaher, Natalija, Jošt, Maja, Kopac, Peter, Košnik, Mitja, Lalek, Nika, Poplas Susic, Antonija, Rozman Sinur, Irma, Soklic Košak, Tanja, Triller, Nadja, Triller, Katja, Urbancic, Jure, Zidarn, Mihaela, Levin, Michael, Potter, Paul, Zar, Heather, Alobid, Isam, Anto, Aram, Bartra, Joan, Bobolea, Irina, Campo, Paloma, Cardona, Vicky, Carriazo Ana, Maria, Castillo Vizuete, José Antonio, Chivato, Tomas, Davila Gonzalez, Ignacio Jesus, Mullol, Joaquim, Nieto Garcia, Antonio, Picado, César, Quirce, Santiago, Sastre, Joaquin, de las Vecillas, Leticia, Benson, Mikael, Kull, Inger, van Hage, Marianne, Wickman, Magnus, Khaltaev, Nikolai, Mohammad, Yousser, Tantilipikorn, Pongsakorn, Vichyanond, Pakit, Cingi, Cemal, Gemicioglu, Bilun, Goksel, Ozlem, Kalayci, Omer, Kalyoncu, Ali Fuat, Meço, Cem, Vardaloglu, Koyuncu Ilgim, Yorgancioglu, Arzu, Karabacak, Deniz Eyice, Kirenga, Bruce, Adcock, Ian Michael, Arshad, Hasan S., Bewick, Mike, Bond, Christine, Brightling, Christopher, Bush, Andrew, Calderon, Moïses, Chung, Kian Fan, Custovic, Adnan, Djukanovic, Ratko, Durham, Stephen, Farrell, John, Halpin, David, Hyland, Michael, Johnston, Sebastian, Lipworth, Brian, Nakonechna, Alla, Price, David, Roberts, Graham, Ryan, Dermot, Schwarze, Jürgen, Sheikh, Aziz, Shields, Mike, Walker, Samantha, Williams, Sian, Kaidashev, Igor, Kurchenko, Andrii Igorevich, Tsaryk, Vladyslav, Bernstein, David, Bernstein, Jonathan A., Casale, Thomas B., Chinthrajah, Sharon, Dykewicz, Mark, Marshall, Gailen D., Meltzer, Eli O., Naclerio, Robert M., Togias, Alkis, Toskala, Elina, Wallace, Dana, Williams, Dennis M., Yawn, Barbara, Caballero-Fonseca, Fernan, Le Thi Tuyet, Lan, Vu, Tran Thien Quan, Gil-Mata, Sara, Teixeira, Tatiana, Bedbrook, Anna, Bousquet, Jean, and Vieira, Rafael José

Published
2024
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2. Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL hypothesis

Author

Bousquet, Jean, Melén, Erik, Haahtela, Tari, Koppelman, Gerard, Togias, Alkis, Valenta, Rudolf, Akdis, Cezmi, Czarlewski, Wienczyslawa, Rothenberg, Marc, Valiulis, Arunas, Wickman, Magnus, Vichyanond, Pakit, Moniuszko, Marcin, Ėmužytė, Regina, Bush, Andrew, Chu, Derek K, Viegi, Giovanni, Wallace, Dana, Durham, Stephen, Wang, De Yun, Vandenplas, O., Just, Jocelyne, Carlsen, Karin C. Lodrup, Passalacqua, Giovanni, Williams, Siân, Linnemann, Désirée Larenas, Loureiro, Cláudia Chaves, Sagara, Hironori, Worm, Margitta, Yiallouros, Panayiotis, Yusuf, Osman, Zaitoun, Fares, Bonini, Matteo, Hrubiško, Martin, Cingi, C., Dykewicz, Mark, Zernotti, Mario, Calderon, Moises, Halpin, David M.G., Zidarn, Mihaela, Patella, Vincenzo, Sheikh, Aziz, Zuberbier, Jaron, Papadopoulos, Nikolaos, Louis, Renaud, Suppli Ulrik, Charlotte, Fonseca, João P., Zuberbier, Torsten, Anto, M. J., Costa, Elisio, Eiwegger, Thomas, Bosnic-Anticevich, Sinthia, Cruz, Alvaro, Sousa, Jaime Correia de, Louis-Philippe, Boulet, Erhola, Marina, Cardona, Victoria, Carr, Warner, Gemicioglu, Bilun, Pawankar, Ruby, Fokkens, Wytske, Calvo, Mário, Garcia-Aymerich, J., Mäkelä, Mika J., Hofmann, Maja Ann, Klimek, Ludger, Makris, Michael, Mohamed Sayed, Zeinab, Maurer, Marcus, D'Amato, G., Momas, Isabelle, Siroux, Valérie, Almeida, Mário Morais, Corrigan, Chris, Mullol, Joaquim, Montefort, Stephen, Jutel, Marek, Pham Thi, Nhan, Hossny, Elham, Akdis, Mubeccel, Pfaar, Oliver, Ventura, Maria Teresa, Regateiro, Frederico S., Bindslev-Jensen, Carsten, Ring, Johannes, Bustamante, Mariona, Pinto, Bernardo Sousa, Kaidashev, Igor, Guerra, Stefano, Standl, Marie, Sunyer, J., Keil, Thomas, Barata, Luís Taborda, Camargos, Paulo, Weiss, Scott, Naclerio, Robert, Yorgancıoglu, Arzu, Zhang, Luo, Nadeau, Kari, Abdul Latiff, Amir, Aberer, Werner, Heinrich, Joachim, Sisul, Juan, Nunes, Elizabete, Plavec, Davor, Agache, Ioana, Al-Ahmad, Mona, Serpa, Faradiba, Alobid, Isam, Kalayci, Omer, Giacco, S. Del, Fiocchi, Alessandro, Ansotegui Zubeldia, Ignacio Javier, Custovic, Adnan, Martins, Pedro Carreiro, Rouadi, Philip, Arshad, Syed Hasan, Asayag, Estrella, Bárbara, Cristina, Abdullah, Baharudin, Tomazic, Peter Valentin, Popov, T. A., Sayah, Zineb, Lkhagvaa, Battur, Nyembue Tshipukane , Dieudonne, Thomas, Mike, Bennoor, Kazi Saifuddin, Fyhrquist, Nanna Theresia, Irani, Carla, Berghea, Elena Camelia, De Blay, Frédéric, Toppila-Salmi, Sanna Katriina, Bergmann, Karl-Christian, Bernstein, D., Bewick, M., Casale, Thomas, Scheire, Sophie, Bumbacea, Roxana Silvia, Cepeda Sarabia, Alfonso, Puggioni, Francesca, Chandrasekharan, Ramanathan, Ohta, Ken, Okubo, Kimihiro, Charpin, Denis, Gomez, R Maximiliano, Chen, Y. Z., O'Hehir, Robyn, Cherrez Ojeda, Ivan, Bedbrook, Anna, To, Teresa, Devillier, Philippe, Schmid-Grendelmeier, Peter, Didier, Alain, Repka-Ramirez, María Susana, Teixeira, Maria Do Céu, Ispayeva, Zhanat, Dokic, Dejan, Quirce, Santiago, Douagui , Habib, Ivancevich, Juan Carlos, Gotua, Maia, Todo-Bom, Ana, Blain, Hubert, Guzman, Maria Antonieta, Kalyoncu, Ali Fuat, Hagemann, Jan, Buhl, Roland, Hamamah, Samir, Caraballo, Luis, Jares, Edgardo, Chivato, Tomás, Jartti, Tuomas, Jassem, Ewa, Christoff, George, Julge, Kalev, Ogulur, Ismail, Kardas, Przemyslaw, Doulaptsi, Maria, Kirenga, Bruce, Helga, Kraxner, Kull, Inger, Kulus, Marek, Daniel, Aguilar, Shamji, Mohamed, Kuna, Piotr, Nadif, Rachel, La Grutta, Stefania, Brightling, Chris, Samoliński, Bolesław, Lau, Susanne, Cordeiro, Carlos Manuel Da Silva Robalo, Solé, Dirceu, Le Thi Tuyet, Lan, Recto, Marysia, Ouedraogo, Solange, Halken, Susanne, Levin, Michael, Lipworth, Brian, Lourenço, Olga, Mahboub, Bassam, Niedoszytko, Marek, Sastre, Joaquin, Martinez‐Infante, E., Kupczyk, Maciej, Torres, María Jose, Matricardi, Paolo Maria, Cecchi, Lorenzo, Celedón, Juan C, Miculinic, Neven, Roche, Nicolas, Migueres, Nicolas, Brussino, Luisa, Florin, Mihaltan, Olze, Heidi, Savouré, Marine, Nekam, Kristof, Pali, Isabella, Okamoto, Yoshitaka, Palomares, O., Lemonnier, Nathanaël, Palosuo, Kati, Soto-Martinez, Manuel, Panaitescu, Carmen, Kvedarienė, Violeta, Panzner, P., Braido, Fulvio, Tsiligianni, Ioanna, Rodriguez-Gonzalez, Monica, Scichilone, Nicola, Canonica, Giogio Walter, Romantowski, Jan, Urrutia-Pereira, Marilyn, Filho, Nelson Augusto Rosario, Ollert, Markus W., Rottem, Menachem, Chkhartishvili, Ekaterine, Sova, Milan, Valovirta, Erkka, Mohammad, Yousser, Sperl, Annette, Spranger, Otto, Neffen, Hugo, Stelmach, Rafael, Burte, Emilie, Valentin Rostan, Marylin, Park, Hae-Sim, Van Ganse, Eric, Van Hage, Marianne, Pitsios, Constantinos, Vasankari, Tuula, and uBibliorum

Subjects
IL-33, Multimorbidity, Asthma, Toll-like receptors, Rhinitis
Abstract

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis.

Published
2023

3. Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Author

Bousquet, Jean, Anto, Josep M., Czarlewski, Wienczyslawa, Haahtela, Tari, Fonseca, Susana C., Iaccarino, Guido, Blain, Hubert, Vidal, Alain, Sheikh, Aziz, Akdis, Cezmi A., Zuberbier, Torsten, Abdul Latiff, Amir Hamzah, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mubeccel, Al-Ahmad, Mona, Al-Zahab Bassam, Abou, Alburdan, Hussam, Aldrey-Palacios, Oscar, Alvarez Cuesta, Emilio, Alwan Salman, Hiba, Alzaabi, Ashraf, Amade, Salma, Ambrocio, Gene, Angles, Rosana, Annesi-Maesano, Isabella, Ansotegui, Ignacio J., Ara Bardajo, Paula, Arasi, Stefania, Arrais, Margarete, Arshad, Hasan, Artesani, Maria-Cristina, Asayag, Estrella, Bernstein, David, Chatzi, Lida, Chavannes, Niels H., Guldemond, Nick, Mommers, Monique, Papadopoulos, Nikos G., Reitsma, Sietze, Thijs, Carel, ARIA group, Bousquet, Jean, Anto, Josep M., Czarlewski, Wienczyslawa, Haahtela, Tari, Fonseca, Susana C., Iaccarino, Guido, Blain, Hubert, Vidal, Alain, Sheikh, Aziz, Akdis, Cezmi A., Zuberbier, Torsten, Abdul Latiff, Amir Hamzah, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mubeccel, Al-Ahmad, Mona, Al-Zahab Bassam, Abou, Alburdan, Hussam, Aldrey-Palacios, Oscar, Alvarez Cuesta, Emilio, Alwan Salman, Hiba, Alzaabi, Ashraf, Amade, Salma, Ambrocio, Gene, Angles, Rosana, Annesi-Maesano, Isabella, Ansotegui, Ignacio J., Ara Bardajo, Paula, Arasi, Stefania, Arrais, Margarete, Arshad, Hasan, Artesani, Maria-Cristina, Asayag, Estrella, Bernstein, David, Chatzi, Lida, Chavannes, Niels H., Guldemond, Nick, Mommers, Monique, Papadopoulos, Nikos G., Reitsma, Sietze, Thijs, Carel, and ARIA group

Abstract

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.

Published
2021

4. Cabbage and fermented vegetables:From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Author

Bousquet, Jean, Anto, Josep M., Czarlewski, Wienczyslawa, Haahtela, Tari, Fonseca, Susana C., Iaccarino, Guido, Blain, Hubert, Vidal, Alain, Sheikh, Aziz, Akdis, Cezmi A., Zuberbier, Torsten, Hamzah Abdul Latiff, Amir, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mübeccel, Al-Ahmad, Mona, Al-Zahab Bassam, Abou, Alburdan, Hussam, Aldrey-Palacios, Oscar, Alvarez Cuesta, Emilio, Alwan Salman, Hiba, Alzaabi, Ashraf, Amade, Salma, Ambrocio, Gene, Angles, Rosana, Annesi-Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep, Ara Bardajo, Paula, Arasi, Stefania, Arshad, Hasan, Cristina Artesani, Maria, Asayag, Estrella, Avolio, Francesca, Buhl, Roland, Dahl, Ronald, Li, Jing, Malling, Hans Jørgen, Pedersen, Søren, Poulsen, Lars, Suppli Ulrik, Charlotte, Walker, Samantha, Wang, De Yun, Zhang, Luo, Bousquet, Jean, Anto, Josep M., Czarlewski, Wienczyslawa, Haahtela, Tari, Fonseca, Susana C., Iaccarino, Guido, Blain, Hubert, Vidal, Alain, Sheikh, Aziz, Akdis, Cezmi A., Zuberbier, Torsten, Hamzah Abdul Latiff, Amir, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mübeccel, Al-Ahmad, Mona, Al-Zahab Bassam, Abou, Alburdan, Hussam, Aldrey-Palacios, Oscar, Alvarez Cuesta, Emilio, Alwan Salman, Hiba, Alzaabi, Ashraf, Amade, Salma, Ambrocio, Gene, Angles, Rosana, Annesi-Maesano, Isabella, Ansotegui, Ignacio J., Anto, Josep, Ara Bardajo, Paula, Arasi, Stefania, Arshad, Hasan, Cristina Artesani, Maria, Asayag, Estrella, Avolio, Francesca, Buhl, Roland, Dahl, Ronald, Li, Jing, Malling, Hans Jørgen, Pedersen, Søren, Poulsen, Lars, Suppli Ulrik, Charlotte, Walker, Samantha, Wang, De Yun, and Zhang, Luo

Abstract

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT1R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.

Published
2021

5. Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Author

Bousquet, Jean, Anto, Josep M., Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi, Blain, Hubert, Canonica, G. Walter, Cardona, Victoria, Cruz, Alvaro A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas-linnemann, Désirée, Mullol, Joaquim, Papadopoulos, Nikos G., Pfaar, Oliver, Samolinski, Boleslaw, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Latiff, Amir, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mübeccel, Al-Ahmad, Mona, Bassam, Abou Al Zahab, Aldrey-Palacios, Oscar, Cuesta, Emilio Alvarez, Alzaabi, Ashraf, Amad, Salma, Ambrocio, Gene, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep, Arshad, Hasan, Artesani, Maria Cristina, Asayag, Estrella, Avolio, Francesca, Azhari, Khuzama, Baiardini, Ilaria, Bajrović, Nissera, Bakakos, Petros, Mongono, Sergio Bakeyala, Balotro-Torres, Christine, Barba, Sergio, Barbara, Cristina, Barbosa, Elsa, Barreto, Bruno, Bartra, Joan, Bateman, Eric D., Battur, Lkhagvaa, Bedbrook, Anna, Barajas, Martín Bedolla, Beghé, Bianca, Bel, Elizabeth, Kheder, Ali Ben, Benson, Mikael, Berghea, Camelia, Bergmann, Karl Christian, Bernstein, David, Bewick, Mike, Bialek, Slawomir, Białoszewski, Artur, Bieber, Thomas, Billo, Nils, Bilo, Maria Beatrice, Bindslev-Jensen, Carsten, Bjermer, Leif, Marciniak, Malgorzata Bochenska, Bond, Christine, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Botskariova, Sofia, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Bousquet, Philippe, Braido, Fulvio, Briggs, Andrew, Brightling, Christopher, Brozek, Jan, Buhl, Roland, Bumbacea, Roxana, Cabañas, María Teresa Burguete, Bush, Andrew, Busse, William W., Buters, Jeroen, Caballero-Fonseca, Fernan, Calderon, Moïses A., Calvo, Mario, Camargos, Paulo, Camuzat, Thierry, Cano, Antonio, Capriles-Hulett, Arnaldo, Caraballo, Luis, Cardona, Vicky, Carlsen, Kai Hakon, Caro, Jorge, Carreon-Asun-cion, Fredelita, Carriazo, Ana Maria, Casale, Thomas, Castor, Mary Ann, Castro, Elizabeth, Cecchi, Lorenzo, Sarabia, Alfonso Cepeda, Chandrasekharan, Ramanathan, Chang, Yoon Suk, Chato-Andeza, Victoria, Chatzi, Lida, Chatzidaki, Christina, Chavannes, Niels H., Chen, Yuzhi, Cheng, Lei, Chivato, Tomas, Chkhartishvili, Ekaterine, Christoff, George, Chrystyn, Henry, Chu, Derek K., Chua, Antonio, Chuchalin, Alexander, Chung, Kian Fan, Cicerán, Alberto, Cingi, Cemal, Ciprandi, Giorgio, Cirule, Ieva, Coelho, Ana Carla, Constantinidis, Jannis, de Sousa, Jaime Correia, Costa, Elisio, Costa, David, Domínguez, María Del Carmen Costa, Coste, André, Cox, Linda, Cullen, John, Custovic, Adnan, Cvetkovski, Biljana, D’amato, Gennaro, Silva, Jane da, Dahl, Ronald, Dahlen, Sven Erik, Daniilidis, Vasilis, Nahhas, Louei Darjazini, Darsow, Ulf, Blay, Frédéric de, Guia, Eloisa De, Santos, Chato de los, Keenoy, Esteban De Manuel, Vries, Govert De, Deleanu, Diana, Demoly, Pascal, Denburg, Judah, Devillier, Philippe, Didier, Alain, Dimou, Maria, Dinh-Xuan, Anh Tuan, Djukanovic, Ratko, Dokic, Dejan, Domínguez Silva, Margarita Gabriela, Douagui, Habib, Douladiris, Nikolaos, Doulaptsi, Maria, Dray, Gérard, Dubakiene, Ruta, Durham, Stephen, Dykewicz, Mark, Ebo, Didier, Edelbaher, Natalija, Eklund, Patrik, El-Gamal, Yehia, El-Sayed, Zeinab A., El-Sayed, Shereen S., El-Seify, Magda, Emuzyte, Regina, Enecilla, Lourdes, Espinoza, Heidilita, Guillermo, Jesús, Contreras, Espinoza, Farrell, John, Fernandez, Lenora, Wagner, Antje Fink, Fiocchi, Alessandro, Fokkens, Wytske J., Fontaine, Jean François, Forastiere, Francesco, Pèrez, Jose Miguel Fuentes, Gaerlan–resureccion, Emily, Gaga, Mina, Romero, José Luis Gálvez, Gamkrelidze, Amiran, Garcia, Alexis, Cobas, Cecilia Yvonne García, García Cruz, María de la Luz Hortensia, Gayraud, Jacques, Gemicioglu, Bilun, Genova, Sonya, Gereda, José, Wijk, Roy Gerth van, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Grigoreas, Christos, Grisle, Ineta, Guidacci, Marta, Guldemond, Nick, Gutter, Zdenek, Guzmán, Antonieta, Halloum, Ramsa, Hamelmann, Eckard, Hammadi, Suleiman, Harvey, Richard, Heinrich, Joachim, Hejjaoui, Adnan, Hellquist-Dahl, Birthe, Velázquez, Luiana Hernández, Hew, Mark, Hossny, Elham, Howarth, Peter, Hrubiško, Martin, Villalobos, Yunuen Rocío Huerta, Humbert, Marc, Hyland, Michael, Ibrahim, Moustafa, Ilyina, Natalia, Irani, Carla, Ispayeva, Zhanat, Jares, Edgardo, Jarvis, Deborah, Jassem, Ewa, Jenko, Klemen, Uscanga, Rubén Darío Jiméneracruz, Johnston, Sebastian, Joos, Guy, Jošt, Maja, Julge, Kaja, Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor, Kalayci, Omer, Kalyoncu, Fuat, Kapsali, Jeni, Kardas, Przemyslaw, Karjalainen, Jussi, Kasala, Carmela A., Katotomichelakis, Michael, Kazi, Bennoor, Keil, Thomas, Keith, Paul, Khaitov, Musa, Khaltaev, Nikolai, Kim, You Young, Kleine-Tebbe, Jorg, Koffi N’Goran, Bernard, Kompoti, Evangelia, Kopač, Peter, Koppelman, Gerard, Jeverica, Anja Koren, Košnik, Mitja, Kostov, Kosta V., Kowalski, Marek L., Kralimarkova, Tanya, Vrščaj, Karmen Kramer, Kraxner, Helga, Kreft, Samo, Kritikos, Vicky, Kudlay, Dmitry, Kull, Inger, Kupczyk, Maciej, Kvedariene, Violeta, Kyriakakou, Marialena, Lalek, Nika, Lane, Stephen, Larenas-Linnemann, Désiree, Lau, Susanne, Lavrut, Jorge, Le, Lan, Lessa, Marcus, Levin, Michael, Li, Jing, Lieberman, Philip, Liotta, Giuseppe, Lipworth, Brian, Liu, Xuandao, Lobo, Rommel, Lodrup Carlsen, Karin C., Lombardi, Carlo, Louis, Renaud, Loukidis, Stelios, Lourenço, Olga, Luna Pech, Jorge A., Madjar, Bojan, Magnan, Antoine, Mahboub, Bassam, Mair, Alpana, Mais, Yassin, van der Zee, Anke Hilse Maitland, Makela, Mika, Makris, Michael, Malling, Hans Jorgen, Mandajieva, Mariana, Manning, Patrick, Manousakis, Manolis, Maragoudakis, Pavlos, Marshall, Gailen, Martins, Pedro, Reza Masjedi, Mohammad, Máspero, Jorge F., Campos, Juan José Matta, Maurer, Marcus, Mavale-Manuel, Sandra, Meço, Cem, Melén, Erik, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Menzies-Gow, Andrew, Merk, Hans, Michel, Jean Pierre, Miculinic, Neven, Midão, Luís, Mihaltan, Florin, Mikael, Kuitunen, Mikos, Nikolaos, Milenkovic, Branislava, Mitsias, Dimitrios, Moalla, Bassem, Moda, Giuliana, Martínez, María Dolores Mogica, Mohammad, Yousser, Moin, Mostafa, Molimard, Mathieu, Momas, Isabelle, Monaco, Alessandro, Montefort, Steve, Mora, Dory, Morais-Almeida, Mario, Mösges, Ralph, Mostafa, Badr Eldin, Münter, Lars, Muraro, Antonella, Murray, Ruth, Mustakov, Tihomir, Naclerio, Robert, Nadif, Rachel, Nakonechna, Alla, Namazova-Baranova, Leyla, Navarro-Locsin, Gretchen, Neffen, Hugo, Nekam, Kristof, Neou, Angelos, Nicod, Laurent, Niederberger-Leppin, Verena, Niedoszytko, Marek, Nieto, Antonio, Novellino, Ettore, Nunes, Elizabete, Nyembue, Dieudonné, O’hehir, Robyn, Odjakova, Cvetanka, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimi, Oliver, Brian, Onorato, Gabrielle L., Orru, Maria Pia, Ouédraogo, Solange, Ouoba, Kampadilemba, Paggiaro, Pier Luigi, Pagkalos, Aris, Palaniappan, S. P., Pali-Schöll, Isabella, Palkonen, Susanna, Palmer, Stephen, Bunu, Carmen Panaitescu, Panzner, Petr, Papanikolaou, Vasilis, Papi, Alberto, Paralchev, Bojidar, Paraskevopoulos, Giannis, Park, Hae Sim, Passalacqua, Giovanni, Patella, Vincenzo, Pavord, Ian, Pawankar, Ruby, Pedersen, Soren, Peleve, Susete, Pereira, Ana, Pérez, Tamara, Pham-Thi, Nhân, Pigearias, Bernard, Pin, Isabelle, Piskou, Konstantina, Pitsios, Constantinos, Pitsios, Kostas, Plavec, Davor, Poethig, Dagmar, Pohl, Wolfgang, Susic, Antonija Poplas, Popov, Todor A., Portejoie, Fabienne, Potter, Paul, Poulsen, Lars, Prados-Torres, Alexandra, Prarros, Fotis, Price, David, Prokopakis, Emmanuel, Puy, Robert, Rabe, Klaus, Raciborski, Filip, Ramos, Josephine, Recto, Marysia T., Reda, Shereen M., Regateiro, Frederico, Reider, Norbert, Reitsma, Sietze, Repka-Ramirez, Susana, Rimmer, Janet, Yeverino, Daniela Rivero, Rizzo, José Angelo, Robalo-Cordeiro, Carlos, Roberts, Graham, Roche, Nicolas, González, Mónica Rodríguez, Zagal, Eréndira Rodríguez, Rolland, Christine, Roller-Wirns-berger, Regina, Rodriguez, Miguel Roman, Romano, Antonino, Rombaux, Philippe, Romualdez, Joel, Rosado-Pinto, Jose, Rosario, Nelson, Rosenwasser, Lanny, Rottem, Menachem, Rouadi, Philip, Rovina, Nikoleta, Sinur, Irma Rozman, Ruiz, Mauricio, Segura, Lucy Tania Ruiz, Ryan, Dermot, Sagara, Hironori, Sakai, Daiki, Sakurai, Daiju, Saleh, Wafaa, Salimaki, Johanna, Salina, Husain, Samitas, Konstanti Nos, Coronel, María Guadalupe Sánchez, Sanchez-Borges, Mario, Sanchez-Lopez, Jaime, Sarafoleanu, Codrut, Serpa, Faradiba Sarquis, Sastre-Dominguez, Joaquin, Scadding, Glenis, Scheire, Sophie, Schmid-Grendelmeier, Peter, Schuhl, Juan Francisco, Schunemann, Holger, Schvalbová, Maria, Scichilone, Nicola, Sepúlveda, Cecilia, Serrano, Elie, Sheikh, Aziz, Shields, Mike, Shishkov, Vasil, Siafakas, Nikos, Simeonov, Alexander, Simons, Estelle F., Sisul, Juan Carlos, Sitkauskiene, Brigita, Skrindo, Ingelbjorg, Košak, Tanja Soklič, Solé, Dirceu, Sooronbaev, Talant, Soto-Martinez, Manuel, Sova, Milan, Spertini, François, Spranger, Otto, Stamataki, Sofia, Stefanaki, Lina, Stellato, Cristiana, Stelmach, Rafael, Sterk, Peter, Strandberg, Timo, Stute, Petra, Subramaniam, Abirami, Suppli Ulrik, Charlotte, Sutherland, Michael, Sylvestre, Silvia, Syrigou, Aikaterini, Barata, Luis Taborda, Takovska, Nadejda, Tan, Rachel, Tan, Frances, Tan, Vincent, Tang, Ing Ping, Taniguchi, Masami, Tannert, Line, Tattersall, Jessica, Teixeira, Maria Do Ceu, Thijs, Carel, Thomas, Mike, To, Teresa, Todo-Bom, Ana Maria, Togias, Alkis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Toskala, Elina, Triggiani, Massimo, Triller, Nadja, Triller, Katja, Tsiligianni, Ioanna, Ulmeanu, Ruxandra, Urbancic, Jure, Pereira, Marilyn Urrutia, Vachova, Martina, Valdés, Felipe, Valenta, Rudolf, Rostan, Marylin Valentin, Valero, Antonio, Vallianatou, Mina, Valovirta, Erkka, Eerd, Michiel Van, Ganse, Eric Van, Hage, Marianne van, Vandenplas, Olivier, Vasankari, Tuula, Vassileva, Dafina, Ventura, Teresa, Vera-Munoz, Cécilia, Vicheva, Dilyana, Vichyanond, Pakit, Vidgren, Petra, Viegi, Giovanni, Vogelmeier, Claus, Hertzen, Leena Von, Vontetsianos, Theodoros, Vourdas, Dimitris, Wagenmann, Martin, Walker, Samantha, Wallace, Dana, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Sian, Williams, Dennis, Wilson, Nicola, Woo, Kent, Wright, John, Wroczynski, Piotr, Xepapadaki, Paraskevi, Yakovliev, Plamen, Yamaguchi, Masao, Yan, Kwok, Yap, Yoke Yeow, Yawn, Barbara, Yiallouros, Panayiotis, Yoshihara, Shigemi, Young, Ian, Yusuf, Osman B., Zaidi, Asghar, Zaitoun, Fares, Zar, Heather, Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, Zubrinich, Celia, Bousquet, Jean, Anto, Josep M., Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi, Blain, Hubert, Canonica, G. Walter, Cardona, Victoria, Cruz, Alvaro A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas-linnemann, Désirée, Mullol, Joaquim, Papadopoulos, Nikos G., Pfaar, Oliver, Samolinski, Boleslaw, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Latiff, Amir, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mübeccel, Al-Ahmad, Mona, Bassam, Abou Al Zahab, Aldrey-Palacios, Oscar, Cuesta, Emilio Alvarez, Alzaabi, Ashraf, Amad, Salma, Ambrocio, Gene, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep, Arshad, Hasan, Artesani, Maria Cristina, Asayag, Estrella, Avolio, Francesca, Azhari, Khuzama, Baiardini, Ilaria, Bajrović, Nissera, Bakakos, Petros, Mongono, Sergio Bakeyala, Balotro-Torres, Christine, Barba, Sergio, Barbara, Cristina, Barbosa, Elsa, Barreto, Bruno, Bartra, Joan, Bateman, Eric D., Battur, Lkhagvaa, Bedbrook, Anna, Barajas, Martín Bedolla, Beghé, Bianca, Bel, Elizabeth, Kheder, Ali Ben, Benson, Mikael, Berghea, Camelia, Bergmann, Karl Christian, Bernstein, David, Bewick, Mike, Bialek, Slawomir, Białoszewski, Artur, Bieber, Thomas, Billo, Nils, Bilo, Maria Beatrice, Bindslev-Jensen, Carsten, Bjermer, Leif, Marciniak, Malgorzata Bochenska, Bond, Christine, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Botskariova, Sofia, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Bousquet, Philippe, Braido, Fulvio, Briggs, Andrew, Brightling, Christopher, Brozek, Jan, Buhl, Roland, Bumbacea, Roxana, Cabañas, María Teresa Burguete, Bush, Andrew, Busse, William W., Buters, Jeroen, Caballero-Fonseca, Fernan, Calderon, Moïses A., Calvo, Mario, Camargos, Paulo, Camuzat, Thierry, Cano, Antonio, Capriles-Hulett, Arnaldo, Caraballo, Luis, Cardona, Vicky, Carlsen, Kai Hakon, Caro, Jorge, Carreon-Asun-cion, Fredelita, Carriazo, Ana Maria, Casale, Thomas, Castor, Mary Ann, Castro, Elizabeth, Cecchi, Lorenzo, Sarabia, Alfonso Cepeda, Chandrasekharan, Ramanathan, Chang, Yoon Suk, Chato-Andeza, Victoria, Chatzi, Lida, Chatzidaki, Christina, Chavannes, Niels H., Chen, Yuzhi, Cheng, Lei, Chivato, Tomas, Chkhartishvili, Ekaterine, Christoff, George, Chrystyn, Henry, Chu, Derek K., Chua, Antonio, Chuchalin, Alexander, Chung, Kian Fan, Cicerán, Alberto, Cingi, Cemal, Ciprandi, Giorgio, Cirule, Ieva, Coelho, Ana Carla, Constantinidis, Jannis, de Sousa, Jaime Correia, Costa, Elisio, Costa, David, Domínguez, María Del Carmen Costa, Coste, André, Cox, Linda, Cullen, John, Custovic, Adnan, Cvetkovski, Biljana, D’amato, Gennaro, Silva, Jane da, Dahl, Ronald, Dahlen, Sven Erik, Daniilidis, Vasilis, Nahhas, Louei Darjazini, Darsow, Ulf, Blay, Frédéric de, Guia, Eloisa De, Santos, Chato de los, Keenoy, Esteban De Manuel, Vries, Govert De, Deleanu, Diana, Demoly, Pascal, Denburg, Judah, Devillier, Philippe, Didier, Alain, Dimou, Maria, Dinh-Xuan, Anh Tuan, Djukanovic, Ratko, Dokic, Dejan, Domínguez Silva, Margarita Gabriela, Douagui, Habib, Douladiris, Nikolaos, Doulaptsi, Maria, Dray, Gérard, Dubakiene, Ruta, Durham, Stephen, Dykewicz, Mark, Ebo, Didier, Edelbaher, Natalija, Eklund, Patrik, El-Gamal, Yehia, El-Sayed, Zeinab A., El-Sayed, Shereen S., El-Seify, Magda, Emuzyte, Regina, Enecilla, Lourdes, Espinoza, Heidilita, Guillermo, Jesús, Contreras, Espinoza, Farrell, John, Fernandez, Lenora, Wagner, Antje Fink, Fiocchi, Alessandro, Fokkens, Wytske J., Fontaine, Jean François, Forastiere, Francesco, Pèrez, Jose Miguel Fuentes, Gaerlan–resureccion, Emily, Gaga, Mina, Romero, José Luis Gálvez, Gamkrelidze, Amiran, Garcia, Alexis, Cobas, Cecilia Yvonne García, García Cruz, María de la Luz Hortensia, Gayraud, Jacques, Gemicioglu, Bilun, Genova, Sonya, Gereda, José, Wijk, Roy Gerth van, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Grigoreas, Christos, Grisle, Ineta, Guidacci, Marta, Guldemond, Nick, Gutter, Zdenek, Guzmán, Antonieta, Halloum, Ramsa, Hamelmann, Eckard, Hammadi, Suleiman, Harvey, Richard, Heinrich, Joachim, Hejjaoui, Adnan, Hellquist-Dahl, Birthe, Velázquez, Luiana Hernández, Hew, Mark, Hossny, Elham, Howarth, Peter, Hrubiško, Martin, Villalobos, Yunuen Rocío Huerta, Humbert, Marc, Hyland, Michael, Ibrahim, Moustafa, Ilyina, Natalia, Irani, Carla, Ispayeva, Zhanat, Jares, Edgardo, Jarvis, Deborah, Jassem, Ewa, Jenko, Klemen, Uscanga, Rubén Darío Jiméneracruz, Johnston, Sebastian, Joos, Guy, Jošt, Maja, Julge, Kaja, Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor, Kalayci, Omer, Kalyoncu, Fuat, Kapsali, Jeni, Kardas, Przemyslaw, Karjalainen, Jussi, Kasala, Carmela A., Katotomichelakis, Michael, Kazi, Bennoor, Keil, Thomas, Keith, Paul, Khaitov, Musa, Khaltaev, Nikolai, Kim, You Young, Kleine-Tebbe, Jorg, Koffi N’Goran, Bernard, Kompoti, Evangelia, Kopač, Peter, Koppelman, Gerard, Jeverica, Anja Koren, Košnik, Mitja, Kostov, Kosta V., Kowalski, Marek L., Kralimarkova, Tanya, Vrščaj, Karmen Kramer, Kraxner, Helga, Kreft, Samo, Kritikos, Vicky, Kudlay, Dmitry, Kull, Inger, Kupczyk, Maciej, Kvedariene, Violeta, Kyriakakou, Marialena, Lalek, Nika, Lane, Stephen, Larenas-Linnemann, Désiree, Lau, Susanne, Lavrut, Jorge, Le, Lan, Lessa, Marcus, Levin, Michael, Li, Jing, Lieberman, Philip, Liotta, Giuseppe, Lipworth, Brian, Liu, Xuandao, Lobo, Rommel, Lodrup Carlsen, Karin C., Lombardi, Carlo, Louis, Renaud, Loukidis, Stelios, Lourenço, Olga, Luna Pech, Jorge A., Madjar, Bojan, Magnan, Antoine, Mahboub, Bassam, Mair, Alpana, Mais, Yassin, van der Zee, Anke Hilse Maitland, Makela, Mika, Makris, Michael, Malling, Hans Jorgen, Mandajieva, Mariana, Manning, Patrick, Manousakis, Manolis, Maragoudakis, Pavlos, Marshall, Gailen, Martins, Pedro, Reza Masjedi, Mohammad, Máspero, Jorge F., Campos, Juan José Matta, Maurer, Marcus, Mavale-Manuel, Sandra, Meço, Cem, Melén, Erik, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Menzies-Gow, Andrew, Merk, Hans, Michel, Jean Pierre, Miculinic, Neven, Midão, Luís, Mihaltan, Florin, Mikael, Kuitunen, Mikos, Nikolaos, Milenkovic, Branislava, Mitsias, Dimitrios, Moalla, Bassem, Moda, Giuliana, Martínez, María Dolores Mogica, Mohammad, Yousser, Moin, Mostafa, Molimard, Mathieu, Momas, Isabelle, Monaco, Alessandro, Montefort, Steve, Mora, Dory, Morais-Almeida, Mario, Mösges, Ralph, Mostafa, Badr Eldin, Münter, Lars, Muraro, Antonella, Murray, Ruth, Mustakov, Tihomir, Naclerio, Robert, Nadif, Rachel, Nakonechna, Alla, Namazova-Baranova, Leyla, Navarro-Locsin, Gretchen, Neffen, Hugo, Nekam, Kristof, Neou, Angelos, Nicod, Laurent, Niederberger-Leppin, Verena, Niedoszytko, Marek, Nieto, Antonio, Novellino, Ettore, Nunes, Elizabete, Nyembue, Dieudonné, O’hehir, Robyn, Odjakova, Cvetanka, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimi, Oliver, Brian, Onorato, Gabrielle L., Orru, Maria Pia, Ouédraogo, Solange, Ouoba, Kampadilemba, Paggiaro, Pier Luigi, Pagkalos, Aris, Palaniappan, S. P., Pali-Schöll, Isabella, Palkonen, Susanna, Palmer, Stephen, Bunu, Carmen Panaitescu, Panzner, Petr, Papanikolaou, Vasilis, Papi, Alberto, Paralchev, Bojidar, Paraskevopoulos, Giannis, Park, Hae Sim, Passalacqua, Giovanni, Patella, Vincenzo, Pavord, Ian, Pawankar, Ruby, Pedersen, Soren, Peleve, Susete, Pereira, Ana, Pérez, Tamara, Pham-Thi, Nhân, Pigearias, Bernard, Pin, Isabelle, Piskou, Konstantina, Pitsios, Constantinos, Pitsios, Kostas, Plavec, Davor, Poethig, Dagmar, Pohl, Wolfgang, Susic, Antonija Poplas, Popov, Todor A., Portejoie, Fabienne, Potter, Paul, Poulsen, Lars, Prados-Torres, Alexandra, Prarros, Fotis, Price, David, Prokopakis, Emmanuel, Puy, Robert, Rabe, Klaus, Raciborski, Filip, Ramos, Josephine, Recto, Marysia T., Reda, Shereen M., Regateiro, Frederico, Reider, Norbert, Reitsma, Sietze, Repka-Ramirez, Susana, Rimmer, Janet, Yeverino, Daniela Rivero, Rizzo, José Angelo, Robalo-Cordeiro, Carlos, Roberts, Graham, Roche, Nicolas, González, Mónica Rodríguez, Zagal, Eréndira Rodríguez, Rolland, Christine, Roller-Wirns-berger, Regina, Rodriguez, Miguel Roman, Romano, Antonino, Rombaux, Philippe, Romualdez, Joel, Rosado-Pinto, Jose, Rosario, Nelson, Rosenwasser, Lanny, Rottem, Menachem, Rouadi, Philip, Rovina, Nikoleta, Sinur, Irma Rozman, Ruiz, Mauricio, Segura, Lucy Tania Ruiz, Ryan, Dermot, Sagara, Hironori, Sakai, Daiki, Sakurai, Daiju, Saleh, Wafaa, Salimaki, Johanna, Salina, Husain, Samitas, Konstanti Nos, Coronel, María Guadalupe Sánchez, Sanchez-Borges, Mario, Sanchez-Lopez, Jaime, Sarafoleanu, Codrut, Serpa, Faradiba Sarquis, Sastre-Dominguez, Joaquin, Scadding, Glenis, Scheire, Sophie, Schmid-Grendelmeier, Peter, Schuhl, Juan Francisco, Schunemann, Holger, Schvalbová, Maria, Scichilone, Nicola, Sepúlveda, Cecilia, Serrano, Elie, Sheikh, Aziz, Shields, Mike, Shishkov, Vasil, Siafakas, Nikos, Simeonov, Alexander, Simons, Estelle F., Sisul, Juan Carlos, Sitkauskiene, Brigita, Skrindo, Ingelbjorg, Košak, Tanja Soklič, Solé, Dirceu, Sooronbaev, Talant, Soto-Martinez, Manuel, Sova, Milan, Spertini, François, Spranger, Otto, Stamataki, Sofia, Stefanaki, Lina, Stellato, Cristiana, Stelmach, Rafael, Sterk, Peter, Strandberg, Timo, Stute, Petra, Subramaniam, Abirami, Suppli Ulrik, Charlotte, Sutherland, Michael, Sylvestre, Silvia, Syrigou, Aikaterini, Barata, Luis Taborda, Takovska, Nadejda, Tan, Rachel, Tan, Frances, Tan, Vincent, Tang, Ing Ping, Taniguchi, Masami, Tannert, Line, Tattersall, Jessica, Teixeira, Maria Do Ceu, Thijs, Carel, Thomas, Mike, To, Teresa, Todo-Bom, Ana Maria, Togias, Alkis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Toskala, Elina, Triggiani, Massimo, Triller, Nadja, Triller, Katja, Tsiligianni, Ioanna, Ulmeanu, Ruxandra, Urbancic, Jure, Pereira, Marilyn Urrutia, Vachova, Martina, Valdés, Felipe, Valenta, Rudolf, Rostan, Marylin Valentin, Valero, Antonio, Vallianatou, Mina, Valovirta, Erkka, Eerd, Michiel Van, Ganse, Eric Van, Hage, Marianne van, Vandenplas, Olivier, Vasankari, Tuula, Vassileva, Dafina, Ventura, Teresa, Vera-Munoz, Cécilia, Vicheva, Dilyana, Vichyanond, Pakit, Vidgren, Petra, Viegi, Giovanni, Vogelmeier, Claus, Hertzen, Leena Von, Vontetsianos, Theodoros, Vourdas, Dimitris, Wagenmann, Martin, Walker, Samantha, Wallace, Dana, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Sian, Williams, Dennis, Wilson, Nicola, Woo, Kent, Wright, John, Wroczynski, Piotr, Xepapadaki, Paraskevi, Yakovliev, Plamen, Yamaguchi, Masao, Yan, Kwok, Yap, Yoke Yeow, Yawn, Barbara, Yiallouros, Panayiotis, Yoshihara, Shigemi, Young, Ian, Yusuf, Osman B., Zaidi, Asghar, Zaitoun, Fares, Zar, Heather, Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, and Zubrinich, Celia

Abstract

Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.

Published
2020

6. Resumen ejecutivo de ARIA 2019: Vías integradas de atención para la rinitis alérgica en Argentina, España y México.

Author

Ivancevich, Juan Carlos, primary, Cardona, Victoria, additional, Larenas-Linnemann, Désirée, additional, Mullol, Joaquim, additional, Neffen, Hugo, additional, Zernotti, Mario, additional, Asayag, Estrella, additional, Blua, Ariel Eduardo, additional, Gómez, R. Maximiliano, additional, Jares, Edgardo, additional, Máspero, Jorge, additional, Anto, Josep M., additional, Dedeu, Toni, additional, Rodríguez-González, Mónica, additional, Huerta-Villalobos, Yunuen Rocío, additional, Fuentes-Pérez, José Miguel, additional, Rodríguez-Zagal, Eréndira, additional, Valero, Antonio, additional, Bartra, Joan, additional, Alobid, Isam, additional, Castillo-Vizuete, José Antonio, additional, Dordal, Teresa, additional, Hijano, Rafael, additional, Picado, César, additional, Sastre, Joaquín, additional, Bedolla-Barajas, Martín, additional, Burguete-Cabañas, María Teresa, additional, Costa-Domínguez, María del Carmen, additional, Domínguez-Silva, Margarita, additional, Espinoza-Contreras, Jesús Guillermo, additional, Gálvez-Romero, José Luis, additional, García-Cobas, Cecilia Yvonne, additional, García-Cruz, María de la Luz Hortensia, additional, Hernández-Velázquez, Luiana, additional, Luna-Pech, Jorge A., additional, Matta, Juan José, additional, Mogica-Martínez, María Dolores, additional, Rivero-Yeverino, Daniela, additional, Ruiz, Lucy Tania, additional, Del Río-Navarro, Blanca E., additional, Gómez-Vera, Javier, additional, Macías-Weinmann, Alejandra, additional, Agache, Ionna, additional, Ansotegui, Ignacio, additional, Bachert, Claus, additional, Bedbrook, Anna, additional, Canonica, Giorgio Walter, additional, Casale, Thomas B., additional, Cruz, Álvaro, additional, Fokkens, Wytske, additional, Hellings, Peter, additional, Samolinski, Bolesław, additional, and Bousquet, Jean, additional

Published
2019
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7. Resumen ejecutivo de ARIA 2019: vías integradas de atención para la rinitis alérgica en Argentina, España y México

Author

Ivancevich, Juan Carlos, Cardona, Victoria, Larenas Linnemann, Désirée, Mullol, Joaquim, Neffen, Hugo, Zernotti, Mario Emilio, Asayag, Estrella, Blua, Ariel Eduardo, Gómez, R. Maximiliano, Jares, Edgardo, Máspero, Jorge, Anto, Josep M., Dedeu, Toni, Rodríguez González, Mónica, Huerta Villalobos, Yunuen Rocío, Fuentes Pérez, José Miguel, Rodríguez Zagal, Endira, Valero, Antonio, Bartra, Joan, Alobid, Isam, Castillo Vizuete, José Antonio, Dordal, Teresa, Hijano, Rafael, Picado, César, Sastre, Joaquín, Bedolla Barajas, Martín, Burguete Cabañas, María Teresa, Costa Domínguez, María del Carme, Domínguez Silva, Margarita, Espinoza Contreras, Jesús Guillermo, Gálvez Romero, José Luis, García Cobas, Cecilia Yvonne, García Cruz, María de la Luz Hortensia, Hernández Velázquez, Luiana, Luna Pech, Jorge A., Matta, Juan José, Mogica Martínez, María Dolores, Rivero Yeverino, Daniela, Ruiz, Lucy Tania, Del Río Navarro, Blanca E., Gómez Vera, Javier, Macías Weinmann, Alejandra, Agache, Ionna, Ansotegui, Ignacio, Bachert, Claus, Bedbrook, Anna, Canonica, Giorgio Walter, Casale, Thomas B., Cruz, Álvaro, Fokkens, Wytske, Hellings, Peter, Samolinski, Bolesław, Bousquet, Jean, Ivancevich, Juan Carlos, Cardona, Victoria, Larenas Linnemann, Désirée, Mullol, Joaquim, Neffen, Hugo, Zernotti, Mario Emilio, Asayag, Estrella, Blua, Ariel Eduardo, Gómez, R. Maximiliano, Jares, Edgardo, Máspero, Jorge, Anto, Josep M., Dedeu, Toni, Rodríguez González, Mónica, Huerta Villalobos, Yunuen Rocío, Fuentes Pérez, José Miguel, Rodríguez Zagal, Endira, Valero, Antonio, Bartra, Joan, Alobid, Isam, Castillo Vizuete, José Antonio, Dordal, Teresa, Hijano, Rafael, Picado, César, Sastre, Joaquín, Bedolla Barajas, Martín, Burguete Cabañas, María Teresa, Costa Domínguez, María del Carme, Domínguez Silva, Margarita, Espinoza Contreras, Jesús Guillermo, Gálvez Romero, José Luis, García Cobas, Cecilia Yvonne, García Cruz, María de la Luz Hortensia, Hernández Velázquez, Luiana, Luna Pech, Jorge A., Matta, Juan José, Mogica Martínez, María Dolores, Rivero Yeverino, Daniela, Ruiz, Lucy Tania, Del Río Navarro, Blanca E., Gómez Vera, Javier, Macías Weinmann, Alejandra, Agache, Ionna, Ansotegui, Ignacio, Bachert, Claus, Bedbrook, Anna, Canonica, Giorgio Walter, Casale, Thomas B., Cruz, Álvaro, Fokkens, Wytske, Hellings, Peter, Samolinski, Bolesław, and Bousquet, Jean

Abstract

El impacto sanitario y económico de las enfermedades alérgicas está aumentando rápidamente y se necesitan cambios en las estrategias para su manejo. Su influencia reduce al menos en un tercio la capacidad de desempeño laboral y escolar. Los ICP (Vías Integradas de Atención) de las enfermedades de las vías respiratorias son planes de atención estructurados y multidisciplinarios, que promueven las recomendaciones de las guías en protocolos locales y su aplicación a la práctica clínica. En este documento se presenta un resumen ejecutivo para Argentina, México y España. Se desarrollan las guías ARIA de próxima generación para el tratamiento farmacológico de la rinitis alérgica (RA) utilizando las pautas basadas en GRADE para RA, probadas con evidencia de la vida real proporcionada por tecnología móvil basada en escalas visuales analógicas. Se concluye que en el tratamiento de la RA, los antihistamínicos anti-H1 son menos efectivos que los corticoides intranasales (CINS), que en la rinitis grave los CINS representan la primera línea de tratamiento, y que la combinación intranasal de CINS + anti-H1 es más eficaz que la monoterapia. Sin embargo, según el estudio MASK observacional en vida real, los pacientes tienen pobre adherencia al tratamiento y frecuentemente se automedican de acuerdo con sus necesidades., Fil: Ivancevich, Juan Carlos. Universidad del Salvador. Facultad de Medicina; Argentina, Fil: Cardona, Victoria. Hospital Vall d’Hebron; España, Fil: Larenas Linnemann, Désirée. Médica Sur. Centro de Excelencia en Asma y Alergia; México, Fil: Mullol, Joaquim. Universitat de Barcelona. Instituto de Investigaciones Biomédicas August Pi i Sunye; España, Fil: Neffen, Hugo. Centro de Alergia, Inmunología y Enfermedades Respiratorias; Argentina, Fil: Zernotti, Mario Emilio. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Asayag, Estrella. Sociedad Argentina de Alergia e Inmunopatología; Argentina, Fil: Blua, Ariel Eduardo. Asociación Argentina de Medicina Respiratoria; Argentina, Fil: Gómez, R. Maximiliano. Hospital San Bernardo Salta; Argentina, Fil: Jares, Edgardo. Fundación Libra; Argentina, Fil: Máspero, Jorge. Asociación Argentina de Alergia e Inmunología Clínica; Argentina, Fil: Anto, Josep M. Universidad Pompeu Fabra; España, Fil: Dedeu, Toni. European Regional and Local Health Association; Bélgica, Fil: Rodríguez-González, Mónica. Hospital Español; México, Fil: Huerta Villalobos, Yunuen Rocío. Instituto Mexicano del Seguro Social; México, Fil: Fuentes Pérez, José Miguel. Instituto Mexicano del Seguro Social; México, Fil: Rodríguez Zagal, Endira. Instituto Mexicano del Seguro Social; México, Fil: Valero, Antonio. Universidad de Barcelona; España, Fil: Bartra, Joan. Hospital Clínic Barcelona; España, Fil: Alobid, Isam. Hospital de La Fe; España, Fil: Castillo Vizuete, José Antonio. Hospital Universitari Quirón Dexeus; España, Fil: Dordal, Teresa. Hospital Municipal Badalona; España, Fil: Hijano, Rafael. Hospital del Mar; España, Fil: Picado, César. European Federation of Allergy and Respiratory Diseases Patients; España, Fil: Sastre, Joaquín. Fundación Jiménez Díaz; España, Fil: Bedolla Barajas, Martín. Hospital Civil de Guadalajara Dr. Juan I. Menchaca; México, Fil: Burguete Cabañas, María Teresa. Centro Médico Zambrano Hellion; México, Fil: Costa Domínguez, María del Carme. Instituto Mexicano del Seguro Social; México, Fil: Domínguez-Silva, Margarita. Instituto Mexicano del Seguro Social; México, Fil: Espinoza Contreras, Jesús Guillermo. Hospital Star Médica Aguascalientes; México, Fil: Gálvez Romero, José Luis. Hospital Ángeles de Puebla; México, Fil: García Cobas, Cecilia Yvonne. Instituto Mexicano del Seguro Socia; México, Fil: García Cruz, María de la Luz Hortensia. Instituto Mexicano del Seguro Social; México, Fil: Hernández Velázquez, Luiana. Universidad Autónoma de Baja California Campus Ensenada; México, Fil: Luna-Pech, Jorge A. Universidad de Guadalajara; México, Fil: Matta, Juan José. Instituto Mexicano del Seguro Social; México, Fil: Mogica Martínez, María Dolores. Instituto Mexicano del Seguro Social; México, Fil: Rivero Yeverino, Daniela. Universidad Autónoma de Puebla; México, Fil: Ruiz, Lucy Tania. Instituto Mexicano del Seguro Social; México, Fil: Del Río Navarro, Blanca E. Hospital Infantil de México; México, Fil: Gómez Vera, Javier. Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado; México, Fil: Macías Weinmann, Alejandra. Universidad Autónoma de Nuevo León; México, Fil: Agache, Ionna. Universidad Brasov de Transilvania; Rumania, Fil: Ansotegui, Ignacio. Hospital Quirón Bizkaia; España, Fil: Bachert, Claus. Hospital Universitario de Ghent; Bélgica, Fil: Bedbrook, Anna. MACVIA-Francia-Fundación FMC VIA-LR; Francia, Fil: Canonica, Giorgio Walter. Hospital de Investigación Humanitas; Italia, Fil: Casale, Thomas B. Universidad del Sur de Florida; Estados Unidos, Fil: Cruz, Álvaro. Universidad Federal de Bahía; Brasil, Fil: Fokkens, Wytske. Centros Médicos Académicos; Países Bajos, Fil: Hellings, Peter. Hospitales Universitarios de Leuven; Bélgica, Fil: Samolinski, Bolesław. Universidad Médica de Varsovia; Polonia, Fil: Bousquet, Jean. MACVIA-Francia-Fundación FMC VIA-LR; Francia

Published
2019

8. [ARIA 2016 executive summary: Integrated care pathways for predictive medicine throughout the life cycle in Argentina]

Author

Ivancevich, Juan Carlos, Neffen, Hugo, Zernotti, Mario E., Asayag, Estrella, Blua, Ariel, Ciceran, Alberto, Jares, Edgardo J., Lavrut, Alberto J., Maspero, Jorge F., Agache, Ioana, Bachert, Claus, Bedbrook, Anna, Canonica, Giorgio W., Casale, Thomas B., Cruz, Alvaro A., Fokkens, Wytske J., Peter Hellings, Samolinski, Boleslaw, Bousquet, Jean, Ghent University Hospital, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Medical University of Warsaw - Poland, Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)

Subjects
lcsh:Immunologic diseases. Allergy, EIP on AHA, Visual Analog Scale, [SDV]Life Sciences [q-bio], Tecnologías de la Información y la Comunicación, Clinical Decision-Making, Argentina, World Health Organization, Iniciativa ARIA, Medical Records, User-Computer Interface, Surveys and Questionnaires, Mobile technology, Tecnología móvil, Humans, Healthcare Disparities, Airways ICPs, Rinitis, Rhinitis, Vías de atención integradas para las enfermedades de las vías respiratorias, Delivery of Health Care, Integrated, Health Plan Implementation, Disease Management, Mobile Applications, Rhinitis, Allergic, Asthma, ARIA initiative, Asociación Europea de Innovación para un Envejecimiento Activo y Saludable, ICT, Smartphone, lcsh:RC581-607
Abstract

The ARIA initiative was started during a World Health Organization workshop in 1999. The initial goals were to propose a new classification for allergic rhinitis, to promote the concept of multi-morbidity in asthma and rhinitis and to develop guidelines with stakeholders for world-wide use. ARIA is now focused on the implementation of emerging technologies for individualized and predictive medicine. MASK: MACVIA-Aria Sentinel Network uses mobile technology to develop care pathways that enable management by a multidisciplinary group or by patients themselves. An App for iOS and Android uses a visual analogue scale to assess symptom control and work productivity, as well as a clinical decision support system; it is associated with an interoperable tablet for health professionals. The escalation strategy uses recommendations of the European Innovation Partnership on Active and Healthy Ageing. The aim of ARIA's new approach is to provide an active and healthy life to people affected by rhinitis, regardless of age, gender or socioeconomic status, in order to reduce social and health inequalities caused by the disease.La iniciativa ARIA (Rinitis Alérgica y su Impacto en el Asma) se inició durante un taller de la Organización Mundial de la Salud en 1999. Los objetivos iniciales fueron proponer una nueva clasificación de rinitis alérgica, promover el concepto de multimorbilidad en asma y rinitis y desarrollar guías con todas las partes interesadas para su en todos los países y poblaciones. ARIA, difundida e implementada en más de 70 naciones, ahora se centra en la implementación de tecnologías emergentes para la medicina individualizada y predictiva. MASK (MACVIA [Contre les Maladies Chroniques pour un Vieillissement Actif] Aria Sentinel Network) utiliza la tecnología móvil para desarrollar vías de atención que permitan el manejo de la rinitis y del asma por un grupo multidisciplinario o por los propios pacientes. Una aplicación (app) para iOS y Android está disponible en 20 países y 15 idiomas; utiliza una escala analógica visual para evaluar el control de los síntomas y la productividad del trabajo, así como un sistema de apoyo para las decisiones clínicas. Se asocia con una tabla interoperable (que permite intercambiar información) para médicos y otros profesionales de la salud. La estrategia de escalamiento utiliza las recomendaciones de la Asociación Europea de Innovación para el Envejecimiento Activo y Saludable. El objetivo del nuevo enfoque ARIA es proporcionar una vida activa y saludable a las personas afectadas por la rinitis, cualquiera que sea su edad, sexo o condición socioeconómica, con el fin de reducir las desigualdades sociales y de salud causadas por la enfermedad.

Published
2017
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9. Resumen ejecutivo de ARIA 2016: vías integradas de atención para la medicina predictiva a lo largo del ciclo de vida en Argentina

Author

Ivancevich, Juan Carlos, primary, Neffen, Hugo, additional, Zermotti, Mario E., additional, Asayag, Estrella, additional, Blua, Ariel, additional, Cicerán, Alberto, additional, Jares, Edgardo J., additional, Lavrut, Alberto J., additional, Máspero, Jorge F., additional, Agache, Ioana, additional, Bachert, Claus, additional, Bedbrook, Anna, additional, Canonica, Giorgio W., additional, Casale, Thomas B., additional, Cruz, Álvaro A., additional, Fokkens, Wytske J., additional, Hellings, Peter W., additional, Samolinski, Boleslaw, additional, and Bousquet, Jean, additional

Published
2017
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10. Executive Summary of ARIA 2019: Integrated care pathways for allergic rhinitis in Argentina, Spain and Mexico.

Author

Ivancevich, Juan Carlos, Cardona, Victoria, Linnemann, Désirée Larenas, Mullol, Joaquim, Neffen, Hugo, Zernotti, Mario, Asayag, Estrella, Blua, Ariel Eduardo, Gómez, R. Maximiliano, Jares, Edgardo, Máspero, Jorge, Anto, Josep M., Dedeu, Toni, Rodríguez-González, Mónica, Huerta-Villalobos, Yunuen Rocío, Fuentes-Pérez, José Miguel, Rodríguez-Zagal, Eréndira, Valero, Antonio, Bartra, Joan, and Alobid, Isam

Abstract

Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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11. Resumen ejecutivo de ARIA 2016: vías integradas de atención para la medicina predictiva a lo largo del ciclo de vida en Argentina.

Author

Ivancevich, Juan Carlos, Neffen, Hugo, Zernotti, Mario E., Asayag, Estrella, Blua, Ariel, Cicerán, Alberto, Jares, Edgardo J., Lavrut, Alberto J., Máspero, Jorge F., Agache, Ioana, Bachert, Claus, Bedbrook, Anna, Canonica, Giorgio W., Casale, Thomas B., Cruz, Álvaro A., Fokkens, Wytske J., Hellings, Peter W., Samolinski, Boleslaw, and Bousquet, Jean

Abstract

Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2017
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