136 results on '"Asada, Shuhei"'
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2. Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia
3. Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
4. MECOM promotes leukemia progression and inhibits mast cell differentiation through functional competition with GATA2
5. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia
6. Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors
7. Mechanisms involved in hematopoietic stem cell aging
8. Guiding the HBO1 complex function through the JADE subunit
9. CRISPR/Cas9-mediated base-editing enables a chain reaction through sequential repair of sgRNA scaffold mutations
10. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway
11. P407: MITOTIC FIDELITY IS A RESISTANCE MECHANISM TO DECITABINE IN MYELOID TUMORS.
12. Aberrant histone modifications induced by mutant ASXL1 in myeloid neoplasms
13. The role of ASXL1 in hematopoiesis and myeloid malignancies
14. Abstract 6208: Targeting DNA polymerase theta and ATM leads to synergistic killing of mantle cell lymphoma cells
15. Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia
16. Opposing effects of acute versus chronic inhibition of p53 on decitabine’s efficacy in myeloid neoplasms
17. IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia
18. Mitotic Perturbation Is a Key Mechanism of Action of Decitabine in Myeloid Tumor Treatment
19. Hyperactive NK cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia
20. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis
21. CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression
22. Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)
23. IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia.
24. Clonal hematopoiesis and associated diseases: A review of recent findings
25. A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
26. CRISPR/Cas9-mediated Base-editing Enables a Chain Reaction Through Sequential Repair of sgRNA Scaffold Mutations
27. Impaired Osteoblastic Differentiation of MSCs Suppresses Normal Hematopoiesis in MDS
28. 3150 – EPIGENETIC REGULATOR ASXL1 PROMOTES PARASPECKLE FORMATION THROUGH C-TERMINAL INTRINSICALLY DISORDERED REGION IN HEMATOPOIETIC CELLS
29. 3011 – MUTANT ASXL1 INDUCES EXPANSION OF HEMATOPOIETIC STEM CELLS THROUGH ACTIVATION OF AKT/MTOR PATHWAY
30. HHEX promotes myeloid transformation in cooperation with mutant ASXL1
31. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
32. Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment
33. Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation
34. Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells
35. Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1
36. Abstract 4643: Mutant ASXL1 collaborates with HHEX to promote myeloid leukemogenesis
37. Discrimination of Dormant and Active Hematopoietic Stem Cells by G 0 Markers Reveals Dormancy Regulation by Basal Cytoplasmic Calcium
38. Aberrant histone modifications induced by mutant ASXL1 in myeloid neoplasms
39. Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis
40. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
41. Enhanced nickelidation rate in silicon nanowires with interfacial lattice disorder
42. The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1–RUNX1T1
43. Evaluation of controlled strain in silicon nanowire by UV Raman spectroscopy
44. A scalable Si-based micro thermoelectric generator
45. ON current enhancement of nanowire Schottky barrier tunnel field effect transistors
46. Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)
47. Mutant ASXL1 Cooperates with BAP1 to Promote Myeloid Leukemogenesis
48. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
49. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia
50. [Molecular mechanisms by which the mutant ASXL1/BAP1 complex aggravates myeloid leukemia].
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