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2 results on '"Arthur C. Tatum"'

1. Squamous carcinoma of urinary bladder

Author

David F. Paulson, Arthur C. Tatum, Sigmund I. Tannenbaum, and Culley C. Carson

Subjects
Male, medicine.medical_specialty, Urology, medicine.medical_treatment, medicine, Humans, Basal cell, Aged, Neoplasm Staging, Retrospective Studies, Carcinoma, Transitional Cell, Urinary bladder, business.industry, Poorly differentiated, Clinical course, Middle Aged, medicine.disease, Squamous metaplasia, Squamous carcinoma, Radiation therapy, stomatognathic diseases, Transitional cell carcinoma, medicine.anatomical_structure, Urinary Bladder Neoplasms, Carcinoma, Squamous Cell, Female, business
Abstract

The clinical course of 56 patients with squamous cell carcinoma of the urinary bladder and poorly differentiated transitional cell carcinoma with squamous metaplasia were compared. Survival was evaluated to compare treatments and biologic potentials of these neoplasms. Squamous cell carcinoma of the urinary bladder behaves as poorly differentiated transitional cell carcinoma with squamous metaplasia, and survival is significantly poorer than in poorly differentiated transitional cell carcinoma. While survivals are limited, only radical, surgical extirpation can be associated with significant patient salvage.

Published
1983

2. Histologic grading as predictor of response to chemotherapy in patients with prostatic adenocarcinoma

Author

Edwin B. Cox, Arthur C. Tatum, David F. Paulson, Wanda Hinshaw, Stephen A. Kramer, and Ann Walker

Subjects
Oncology, Male, medicine.medical_specialty, Urology, medicine.medical_treatment, Antineoplastic Agents, Adenocarcinoma, urologic and male genital diseases, Prostatic tumor, Prostate, Internal medicine, medicine, Humans, In patient, Grading (tumors), Aged, Chemotherapy, Prostatic adenocarcinoma, business.industry, Prostatic Neoplasms, Middle Aged, medicine.disease, medicine.anatomical_structure, business
Abstract

In patients with hormone-resistant, Stage D adenocarcinoma of the prostate histologic grading using the Gleason classification allowed stratification of a subgroup of patients in whom response to chemotherapy could be predicted from the growth pattern of the original prostatic tumor. Sixteen of 30 patients (53 per cent) with Gleason sums of 6 or 7 demonstrated a response to chemotherapy. Conversely, only 4 of 21 patients (19 per cent) with elevated Gleason sums of 8, 9, or 10 achieved a response to chemotherapy (P

Published
1981

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