23 results on '"Arthritis parasitology"'
Search Results
2. A man in his 80s with arthritis and persistent fever.
- Author
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Blomberg B, Müller KE, Helgeland L, Fladeby C, and Mørch K
- Subjects
- Aged, 80 and over, Amphotericin B administration & dosage, Amphotericin B therapeutic use, Antiprotozoal Agents administration & dosage, Antiprotozoal Agents therapeutic use, Arthritis parasitology, Fever parasitology, Humans, Leishmania infantum growth & development, Leishmania infantum isolation & purification, Leishmaniasis, Visceral complications, Leishmaniasis, Visceral drug therapy, Male, Pancytopenia parasitology, Spain, Splenomegaly diagnostic imaging, Splenomegaly parasitology, Tomography, X-Ray Computed, Travel-Related Illness, Leishmaniasis, Visceral diagnosis
- Abstract
Background: Febrile illness is a common clinical problem and frequently caused by bacterial and viral infections. When blood cultures are negative and symptoms persist despite empirical antibiotic treatment, clinicians must consider other differential diagnoses including malignancy, rheumatologic disease and parasitic infections., Case Presentation: A Norwegian male in his eighties experienced febrile illness during a stay in Southern Spain. Upon return to Norway, he was hospitalized with fever, weight-loss, enlarged spleen, pancytopenia and hypergammaglobulinemia. After failing to respond to broad-spectrum antibiotics and antifungals, he was diagnosed with visceral leishmaniasis and Leishmania infantum was confirmed by PCR and sequencing of spleen biopsy and blood., Interpretation: With increasing migration and tourism, doctors in non-endemic countries should be familiar with visceral leishmaniasis.
- Published
- 2019
- Full Text
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3. Tuberculosis arthritis of the sternoclavicular joint after uncomplicated falciparum malaria: a case report.
- Author
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Djiba B, Kane BS, Diallo MA, Diongue K, Diack ND, Deme H, Dieng M, Sow M, Ndiaye D, and Pouye A
- Subjects
- Antimalarials administration & dosage, Antitubercular Agents administration & dosage, Arthritis drug therapy, Arthritis microbiology, Arthritis parasitology, Female, Humans, Malaria, Falciparum parasitology, Mycobacterium tuberculosis drug effects, Mycobacterium tuberculosis isolation & purification, Mycobacterium tuberculosis physiology, Plasmodium falciparum drug effects, Plasmodium falciparum growth & development, Plasmodium falciparum isolation & purification, Tuberculosis microbiology, Tuberculosis parasitology, Young Adult, Arthritis complications, Malaria, Falciparum complications, Sternoclavicular Joint microbiology, Sternoclavicular Joint parasitology, Tuberculosis complications
- Abstract
Background: Malaria and tuberculosis are co-endemic in many developing countries. However their associations are rarely reported. Yet, it has been suggested that a pathological process may link the two diseases., Case Presentation: A 20-year-old female patient was admitted in the internal medicine service of Aristide Le Dantec Hospital for uncomplicated malaria. She was previously treated for autoimmune hemolytic anaemia using prednisone at 5 mg per day. Clinical examination showed swelling in front of the sternoclavicular joint. She presented with fever and headache. Thick smear from blood revealed trophozoites of P. falciparum at parasite density of 52,300 parasites/μl. The Ziehl-Neelsen stained smear showed the presence of acid-fast bacilli from the fluid puncture of the swelling. Mycobacterium tuberculosis was further isolated in culture. The diagnosis of falciparum malaria co-infection with sternoclavicular tuberculosis was posed. The patient was treated successfully using antimalarial drugs subsequently followed by multidrug antitubercular therapy., Conclusion: Interactions between malaria and tuberculosis need to be largely and prospectively investigated and appropriate treatment should be undertaken.
- Published
- 2017
- Full Text
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4. Th2 and eosinophil responses suppress inflammatory arthritis.
- Author
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Chen Z, Andreev D, Oeser K, Krljanac B, Hueber A, Kleyer A, Voehringer D, Schett G, and Bozec A
- Subjects
- Animals, Arthritis parasitology, Arthritis pathology, Biomarkers metabolism, Cell Count, Eosinophilia complications, Eosinophilia pathology, Humans, Inflammation parasitology, Inflammation pathology, Interleukin-13 metabolism, Interleukin-4 metabolism, Joints pathology, Macrophages metabolism, Macrophages pathology, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Transgenic, Nippostrongylus physiology, STAT6 Transcription Factor metabolism, Strongylida Infections complications, Strongylida Infections immunology, Strongylida Infections parasitology, Strongylida Infections pathology, Tumor Necrosis Factor-alpha metabolism, Arthritis complications, Arthritis immunology, Eosinophils immunology, Inflammation complications, Inflammation immunology, Th2 Cells immunology
- Abstract
Th2-eosinophil immune responses are well known for mediating host defence against helminths. Herein we describe a function of Th2-eosinophil responses in counteracting the development of arthritis. In two independent models of arthritis, Nippostrongylus brasiliensis infection leads to Th2 and eosinophil accumulation in the joints associated with robust inhibition of arthritis and protection from bone loss. Mechanistically, this protective effect is dependent on IL-4/IL-13-induced STAT6 pathway. Furthermore, we show that eosinophils play a central role in the modulation of arthritis probably through the increase of anti-inflammatory macrophages into arthritic joints. The presence of these pathways in human disease is confirmed by detection of GATA3-positive cells and eosinophils in the joints of rheumatoid arthritis patients. Taken together, these results demonstrate that eosinophils and helminth-induced activation of the Th2 pathway axis effectively mitigate the course of inflammatory arthritis.
- Published
- 2016
- Full Text
- View/download PDF
5. Erosive Monoarthritis of the Wrist Secondary to Coccidioides Immitis Infection.
- Author
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Al-Ani M and Parperis KM
- Subjects
- Adult, Humans, Male, Arthritis parasitology, Coccidioidomycosis diagnosis, Wrist Joint
- Published
- 2016
- Full Text
- View/download PDF
6. Chronic polyarthritis as isolated manifestation of toxocariasis.
- Author
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Viola GR, Giacomin MF, França CM, Sallum AM, Jacob CM, and Silva CA
- Subjects
- Animals, Arthritis drug therapy, Child, Preschool, Female, Humans, Toxocariasis drug therapy, Toxocariasis transmission, Zoonoses, Anthelmintics therapeutic use, Arthritis parasitology, Toxocara isolation & purification, Toxocariasis diagnosis
- Abstract
Human toxocariasis is a parasitic zoonosis mainly caused by Toxocara canis or Toxocara cati and is acquired by ingestion of the parasite's embryonated eggs. Arthralgia and/or arthritis were reported in up to 17% of the cases, generally with acute duration (less than 6 weeks). However, to our knowledge, chronic polyarthritis, as the isolated presentation of Toxocara infection, was not reported. One of the 5809 patients that was followed up at our service (0.017%) had chronic polyarthritis as the single manifestation of toxocariasis and was described herein. A 3-year-old girl was referred to our service with severe painful chronic polyarthritis for a period longer than 10 weeks and morning stiffness of 30min. Dog contact exposure history in the recreational areas of neighborhood was reported. Her exams showed high levels of eosinophils in peripheral blood (29%), bone marrow aspirate revealed marked eosinophilia (32%) and Toxocara enzyme-linked immunosorbent assay (Elisa) was positive (1:1280). She was treated with paracetamol (40mg/kg/day) and thiabendazole (25mg/kg/day) for 10 days, and all manifestations reduced. After eight months of follow-up, she was on clinical and laboratorial remission. In conclusion, we described a case of chronic polyarthritis, as isolated manifestation of toxocariasis, mimicking juvenile idiopathic arthritis and leukemia. Importantly, this zoonosis should be considered in patients with arthritis and eosinophilia., (Copyright © 2014 Elsevier Editora Ltda. All rights reserved.)
- Published
- 2016
- Full Text
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7. Reciprocal effects of Schistosoma mansoni infection on spontaneous autoimmune arthritis in IL-1 receptor antagonist-deficient mice.
- Author
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Osada Y, Yamada S, Nakae S, Sudo K, and Kanazawa T
- Subjects
- Animals, Antibodies, Antinuclear blood, Antibodies, Antinuclear immunology, Arthritis immunology, Autoantibodies blood, Autoantibodies immunology, Autoimmune Diseases immunology, Cells, Cultured, Female, Immunoglobulin G blood, Immunoglobulin G immunology, Interleukin-10 biosynthesis, Interleukin-10 blood, Interleukin-17 biosynthesis, Interleukin-17 blood, Interleukin-4 biosynthesis, Interleukin-4 blood, Male, Mice, Mice, Knockout, Rheumatoid Factor blood, Rheumatoid Factor immunology, Spleen immunology, Arthritis parasitology, Autoimmune Diseases parasitology, Receptors, Interleukin-1 deficiency, Schistosomiasis mansoni complications, Schistosomiasis mansoni immunology
- Abstract
Schistosome infections have been shown to prevent inflammation in induced-type arthritis models. However, its effects on spontaneous arthritis remain unknown. We here investigated the effects of Schistosoma mansoni (Sm) infection on spontaneous autoimmune arthritis in IL-1 receptor antagonist (IL-1Ra)-deficient mice. Sm infection partially reduced the severity of arthritis in male IL-1Ra-deficient mice. The splenic responses of IL-17 and TNF-α were reduced, while those of IL-4 and IL-10 were enhanced by the infection. However, Sm infection increased IgG rheumatoid factor and anti-dsDNA IgG serum levels. These results suggest that Sm infection has both ameliorating and exacerbating effects on autoimmunity in IL-1Ra-deficient mice., (Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2015
- Full Text
- View/download PDF
8. Usefulness of Sd30 in the diagnosis of arthritis of filarial origin.
- Author
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Mandal N, Padhy N, Achary KG, Bal M, Satapathy AK, and Kar SK
- Subjects
- Adult, Aged, Aged, 80 and over, Allergens, Arthritis parasitology, Elephantiasis, Filarial parasitology, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunoglobulin G blood, Immunoglobulin M blood, Male, Middle Aged, Young Adult, Antibodies, Helminth blood, Antigens, Helminth, Arthritis diagnosis, Elephantiasis, Filarial diagnosis, Immunologic Tests methods
- Published
- 2014
9. Chronic polyarthritis associated to Cercopithifilaria bainae infection in a dog.
- Author
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Gabrielli S, Giannelli A, Brianti E, Dantas-Torres F, Bufalini M, Fraulo M, La Torre F, Ramos RA, Cantacessi C, Latrofa MS, Cancrini G, and Otranto D
- Subjects
- Animals, Anthelmintics therapeutic use, Arthritis diagnosis, Arthritis drug therapy, Arthritis parasitology, Chronic Disease, Dog Diseases drug therapy, Dog Diseases parasitology, Dogs, Filariasis diagnosis, Filariasis drug therapy, Filariasis parasitology, Filarioidea drug effects, Filarioidea genetics, Italy, Macrolides therapeutic use, Microfilariae, Sequence Analysis, DNA veterinary, Synovial Fluid parasitology, Tick-Borne Diseases diagnosis, Tick-Borne Diseases drug therapy, Tick-Borne Diseases parasitology, Arthritis veterinary, Dog Diseases diagnosis, Filariasis veterinary, Filarioidea isolation & purification, Tick-Borne Diseases veterinary
- Abstract
Despite the widespread distribution of Cercopithifilaria bainae among canine and tick populations worldwide, this filarioid is currently considered of 'minor importance' in veterinary medicine, particularly when compared to related filarioids, such as Dirofilaria immitis and Dirofilaria repens. To date, only a single case of dermatological alterations possibly associated to infection by C. bainae had been reported in a dog. In the present study, we describe the first case of systemic alterations associated to C. bainae infection in a dog suffering from diffused chronic polyarthritis. The animal had a previous history of reluctance to move and stiff gait and displayed multiple joint pain during manipulation of limbs. No biochemical, haematological and X-ray alterations were detected; microfilariae were observed in the synovial fluids collected from the joints. In spite of the morphological and molecular identification of these microfilariae as C. bainae, the dog did not respond to multiple microfilaricidal treatments with milbemicyn oxyme. The potential role of C. bainae in the pathogenesis of this clinical condition is discussed. Given the potential pathogenicity of this parasite, improved knowledge of this little known tick-borne nematode is warranted in order to assist the development of novel and effective treatment strategies., (Copyright © 2014. Published by Elsevier B.V.)
- Published
- 2014
- Full Text
- View/download PDF
10. [Acute arthritis in sarcoidosis: Löfgren's syndrome].
- Author
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Snijders GF and Sprong T
- Subjects
- Acute Disease, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Arthritis drug therapy, Arthritis parasitology, Erythema Nodosum diagnosis, Erythema Nodosum drug therapy, Erythema Nodosum etiology, Humans, Lymphatic Diseases diagnosis, Lymphatic Diseases drug therapy, Male, Middle Aged, Prednisolone therapeutic use, Prognosis, Radiography, Thoracic, Sarcoidosis complications, Sarcoidosis drug therapy, Syndrome, Treatment Outcome, Arthritis diagnosis, Sarcoidosis diagnosis
- Abstract
Sarcoidosis is a systemic inflammatory disease usually presenting with pulmonary symptoms. However, acute arthritis could be the presenting sign of sarcoidosis. We present a 47-year-old man with bilateral arthritis of the ankles, erythema nodosum and bilateral hilar adenopathy on the chest X-ray. This triad is known as Löfgren's syndrome, a form of acute sarcoidosis. He was first treated with an NSAID, followed by a short course of prednisone because of persisting symptoms. After six weeks the patient was asymptomatic. Further investigation showed no decline in pulmonary function. Acute arthritis in patients with sarcoidosis with or without the complete Löfgren's syndrome has a good prognosis. Usually the signs and symptoms will disappear within a few months. Unlike other forms of sarcoidosis, Löfgren's syndrome does not require histological proof of non-caseating granulomas.
- Published
- 2014
11. Photo quiz. A Mauritanian woman with a swollen knee.
- Author
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Crickx E, Buffet P, Caumes É, and Jauréguiberry S
- Subjects
- Adult, Animals, Arthritis parasitology, Calcinosis, Dracunculiasis parasitology, Female, Humans, Knee Joint diagnostic imaging, Mauritius, Radiography, Arthritis diagnosis, Arthritis pathology, Dracunculiasis diagnosis, Dracunculiasis pathology, Dracunculus Nematode isolation & purification, Helminths isolation & purification, Knee Joint pathology
- Published
- 2013
- Full Text
- View/download PDF
12. Schistosoma mansoni infection: an immune complex disease presenting with polyarthritis.
- Author
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Lapa AT, Appenzeller S, and Bértolo MB
- Subjects
- Adult, Alanine Transaminase blood, Arthritis blood, Arthritis diagnosis, Arthritis parasitology, Aspartate Aminotransferases blood, Biomarkers blood, Chronic Disease, Female, Hand Joints diagnostic imaging, Humans, Hypertension, Portal diagnostic imaging, Hypertension, Portal immunology, Hypertension, Portal parasitology, Immune Complex Diseases blood, Immune Complex Diseases diagnosis, Immune Complex Diseases parasitology, Praziquantel therapeutic use, Predictive Value of Tests, Radiography, Rheumatoid Factor blood, Schistosomiasis mansoni blood, Schistosomiasis mansoni diagnosis, Schistosomiasis mansoni drug therapy, Schistosomiasis mansoni parasitology, Schistosomicides therapeutic use, Treatment Outcome, Ultrasonography, Arthritis immunology, Immune Complex Diseases immunology, Schistosomiasis mansoni immunology
- Abstract
Schistosomiasis or bilharzia is a parasitic disease found in tropical countries. Most infections are subclinical but may progress to chronic form characterized most frequently by the presence of liver involvement and portal hypertension. We report a patient that presented chronic polyarthritis with positive rheumatoid factor. During investigation, increased liver enzymes, negative hepatitis serologies and signs of portal hypertension on an ultrasound examination raised suspicion of S. mansoni infection. We will discuss pathophysiology and clinical manifestations of S. mansoni infection with special attention to articular involvement.
- Published
- 2013
- Full Text
- View/download PDF
13. A rare case of disseminated cysticercosis: case report and literature review.
- Author
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Banu A and Veena N
- Subjects
- Animals, Arthritis parasitology, Arthritis pathology, Brain diagnostic imaging, Brain parasitology, Brain pathology, Humans, Lower Extremity diagnostic imaging, Lower Extremity pathology, Lung parasitology, Lung pathology, Male, Middle Aged, Muscle, Skeletal parasitology, Muscle, Skeletal pathology, Radiography, Thoracic, Subcutaneous Tissue parasitology, Subcutaneous Tissue pathology, Tomography, X-Ray Computed, Cysticercosis diagnosis, Cysticercosis pathology, Cysticercus isolation & purification
- Abstract
Cysticercosis is a common tropical disease. One of the uncommon manifestations of cysticercosis and a rare complication is its disseminated form. We report an immunocompetent patient with disseminated cysticercosis who had involvement of the brain, subcutaneous tissues, lungs and skeletal muscles and presented with arthritis. He was otherwise asymptomatic in spite of the extensive involvement of multiple organs. A planned approach to therapy is necessary to prevent complications.
- Published
- 2011
- Full Text
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14. Hydatic synovitis revealed by an acute monoarthritis of the knee.
- Author
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Ben Haha-Bellil S, Chelly I, Zaouia K, Bellil K, Mekni A, Kchir N, Zitouna M, and Haouet S
- Subjects
- Acute Disease, Female, Humans, Knee Joint pathology, Middle Aged, Synovitis pathology, Arthritis parasitology, Echinococcosis complications, Echinococcosis diagnosis, Knee Joint parasitology, Synovitis parasitology
- Published
- 2005
- Full Text
- View/download PDF
15. Early-onset polyarthritis as presenting feature of intestinal infection with Strongyloides stercoralis.
- Author
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van Kuijk AW, Kerstens PJ, Perenboom RM, Dijkmans BA, and Voskuyl AE
- Subjects
- Adult, Animals, Humans, Intestinal Diseases, Parasitic, Male, Strongyloides stercoralis, Arthritis parasitology, Arthritis, Infectious parasitology, Strongyloidiasis complications
- Published
- 2003
- Full Text
- View/download PDF
16. Leishmanial polyarthritis in a dog.
- Author
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McConkey SE, López A, Shaw D, and Calder J
- Subjects
- Animals, Arthritis diagnosis, Arthritis parasitology, Dog Diseases diagnosis, Dogs, Leishmania isolation & purification, Leishmaniasis diagnosis, Macrophages parasitology, Male, Synovial Fluid parasitology, Arthritis veterinary, Dog Diseases parasitology, Leishmaniasis veterinary
- Abstract
A dog adopted as a stray in Spain and then brought to Canada 4 years prior to presentation was evaluated for polyarthritis. An electrophoresis showed a marked polyclonal gammopathy and synovial smears contained leishmanial organisms within macrophages.
- Published
- 2002
17. Increased arthritis severity in mice coinfected with Borrelia burgdorferi and Babesia microti.
- Author
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Moro MH, Zegarra-Moro OL, Bjornsson J, Hofmeister EK, Bruinsma E, Germer JJ, and Persing DH
- Subjects
- Animals, Antibodies, Bacterial blood, Arthritis immunology, Arthritis metabolism, Babesiosis immunology, Babesiosis metabolism, Cytokines analysis, Cytokines biosynthesis, DNA, Bacterial blood, Disease Models, Animal, Enzyme-Linked Immunosorbent Assay, Lyme Disease immunology, Lyme Disease metabolism, Lymph Nodes immunology, Lymph Nodes metabolism, Mice, Mice, Inbred BALB C, Mice, Inbred C3H, Myocarditis immunology, Myocarditis metabolism, Myocarditis microbiology, Myocarditis parasitology, Myocardium pathology, Polymerase Chain Reaction, Spleen immunology, Spleen metabolism, Tarsal Joints pathology, Arthritis microbiology, Arthritis parasitology, Babesia, Babesiosis complications, Borrelia burgdorferi, Lyme Disease complications
- Abstract
Increased severity of disease and persistence of symptoms have been recently reported in some patients with simultaneous infection of Borrelia burgdorferi and Babesia microti in the northeastern and northern midwest United States. This study used a murine model to examine whether defined disease conditions such as arthritis and carditis differed in severity in mice infected solely with B. burgdorferi and in mice coinfected with B. microti and B. burgdorferi. C3H.HeJ and BALB/c mice cohorts were coinfected or singly infected and then monitored experimentally for 15 and 30 days after inoculation. Carditis and arthritis was determined by blinded histopathologic evaluation of myocardium and tibiotarsal joints. Cytokine measurements were made on lymph node and spleen supernatants for interferon-gamma, interleukin (IL)-4, IL-10, and IL-13. No differences were observed for C3H.HeJ mice cohorts; however, coinfected BALB/c mice had a significant increase in arthritis severity at day 30. This clinical observation was correlated with a significant reduction in expression of the cytokines IL-10 and IL-13.
- Published
- 2002
- Full Text
- View/download PDF
18. Sacroiliitis associated with Cryptosporidium parvum in an HLA-B27-negative patient.
- Author
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Ozgül A, Tanyüksel M, Yazicioglu K, and Arpacioglu O
- Subjects
- Adult, Animals, Arthritis immunology, Cryptosporidiosis immunology, Cryptosporidium parvum immunology, HLA-B27 Antigen analysis, Humans, Male, Sacroiliac Joint immunology, Serologic Tests, Arthritis parasitology, Cryptosporidiosis parasitology, Cryptosporidium parvum isolation & purification, Sacroiliac Joint parasitology
- Published
- 1999
- Full Text
- View/download PDF
19. Musculoskeletal syndromes in parasitic diseases.
- Author
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Bocanegra TS and Vasey FB
- Subjects
- Arthritis parasitology, Humans, Musculoskeletal Diseases parasitology
- Abstract
Parasitic infestation can induce a variety of rheumatic syndromes as a result of infiltration of musculoskeletal structures by parasites or an immune mediated mechanism. Parasite-induced symptoms should be considered when arthritis, enthesitis, myositis, or vasculitis develop in patients residing in endemic areas and in certain subsets of the population of developed countries, for example, migrants, travelers, and immunocompromised individuals. Diagnosis is based on the demonstration of infection with a pathogenic parasite, lack of response to anti-inflammatory agents, and improvement following antiparasitic therapy. Treatment consists of erradication of the parasite.
- Published
- 1993
20. Aseptic knee effusion with Loa loa microfilariae in the articular fluid.
- Author
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Roussel F, Roussel C, Brasseur P, Gourmelen O, and Le Loet X
- Subjects
- Animals, Arthritis diagnosis, Arthritis parasitology, Knee Joint, Loa, Loiasis complications, Arthritis etiology, Filariasis diagnosis, Loiasis diagnosis
- Published
- 1989
21. Genes, bacteria and the key to arthritis.
- Author
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Keat A
- Subjects
- Arthritis, Infectious microbiology, Arthritis, Infectious parasitology, Chlamydia Infections complications, Chlamydia trachomatis isolation & purification, Disease Susceptibility, HLA Antigens immunology, Humans, Arthritis genetics, Arthritis immunology, Arthritis microbiology, Arthritis parasitology
- Published
- 1989
22. [Loa loa filarial arthritis with microfiliara in the articular fluid].
- Author
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Jaffres R, Simitzis Le Flohic AM, and Chastel C
- Subjects
- Adult, Arthritis blood, Arthritis etiology, Humans, Male, Microfilariae isolation & purification, Arthritis parasitology, Filariasis parasitology, Loa isolation & purification, Loiasis parasitology, Synovial Fluid parasitology
- Published
- 1983
23. [Reactive arthritis caused by Anguillula and ankylosing spondylarthritis].
- Author
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Menkès CJ, Papo T, Carter H, and Renoux M
- Subjects
- Aged, Arthritis complications, Female, Humans, Arthritis parasitology, Spondylitis, Ankylosing complications, Strongyloidiasis complications
- Published
- 1987
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