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22 results on '"Arriaga, Maria B."'

1. An integrative multi-omics approach to characterize interactions between tuberculosis and diabetes mellitus

Author

Vinhaes, Caian L., Fukutani, Eduardo R., Santana, Gabriel C., Arriaga, María B., Barreto-Duarte, Beatriz, Araújo-Pereira, Mariana, Maggitti-Bezerril, Mateus, Andrade, Alice M.S., Figueiredo, Marina C., Milne, Ginger L., Rolla, Valeria C., Kristki, Afrânio L., Cordeiro-Santos, Marcelo, Sterling, Timothy R., Andrade, Bruno B., and Queiroz, Artur T.L.

Published
2024
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2. Determinants of losses in the tuberculosis infection cascade of care among children and adolescent contacts of pulmonary tuberculosis cases: A Brazilian multi-centre longitudinal study

Author

Sobral, Luciana, Arriaga, María B., Souza, Alexandra B., Araújo-Pereira, Mariana, Barreto-Duarte, Beatriz, Sales, Caio, Rocha, Michael S., Benjamin, Aline, Moreira, Adriana S.R., de Oliveira, Jamile G., Carvalho, Anna Cristina, Spener-Gomes, Renata, Figueiredo, Marina C., Cavalcante, Solange, Durovni, Betina, Lapa-e-Silva, José R., Kritski, Afrânio L., Rolla, Valeria C., Sterling, Timothy R., Cordeiro-Santos, Marcelo, and Andrade, Bruno B.

Published
2022
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5. Novel stepwise approach to assess representativeness of a large multicenter observational cohort of tuberculosis patients: The example of RePORT Brazil

Author

Arriaga, María B., Amorim, Gustavo, Queiroz, Artur T.L., Rodrigues, Moreno M.S., Araújo-Pereira, Mariana, Nogueira, Betania M.F., Souza, Alexandra Brito, Rocha, Michael S., Benjamin, Aline, Moreira, Adriana S.R., de Oliveira, Jamile G., Figueiredo, Marina C., Turner, Megan M., Alves, Kleydson, Durovni, Betina, Lapa-e-Silva, José R., Kritski, Afrânio L., Cavalcante, Solange, Rolla, Valeria C., Cordeiro-Santos, Marcelo, Sterling, Timothy R., and Andrade, Bruno B.

Published
2021
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7. Polymorphisms in interferon pathway genes and risk of Mycobacterium tuberculosis infection in contacts of tuberculosis cases in Brazil

Author

Cubillos-Angulo, Juan Manuel, Arriaga, María B., Melo, Mayla G.M., Silva, Elisangela C., Alvarado-Arnez, Lucia Elena, de Almeida, Alexandre S., Moraes, Milton O., Moreira, Adriana S.R., Lapa e Silva, Jose R., Fukutani, Kiyoshi F., Sterling, Timothy R., Hawn, Thomas R., Kritski, Afrânio L., Oliveira, Martha M., and Andrade, Bruno B.

Published
2020
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10. Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations

Author

Oliveira-de-Souza, Deivide, Vinhaes, Caian L., Arriaga, Maria B., Kumar, Nathella Pavan, Cubillos-Angulo, Juan M., Shi, Ruiru, Wei, Wang, Yuan, Xing, Zhang, Guolong, Cai, Ying, Barry, III, Clifton E., Via, Laura E., Sher, Alan, Babu, Subash, Mayer-Barber, Katrin D., Nakaya, Helder I., Fukutani, Kiyoshi F., and Andrade, Bruno B.

Published
2019
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11. Effect of Dysglycemia on Urinary Lipid Mediator Profiles in Persons With Pulmonary Tuberculosis

Author

Arriaga, Maria B., Karim, F., Queiroz, A.T.L., Araújo-Pereira, M., Barreto-Duarte, B., Sales, C., Moosa, M.-Y.S., Mazibuko, M., Milne, G.L., Maruri, F., Serezani, C.H., Koethe, J.R., Figueiredo, M.C., Kritski, A.L., Cordeiro-Santos, M., Rolla, V.C., Sterling, T.R., Leslie, A., and Andrade, B.B.

Subjects
dysglycemia, urinary eicosanoids, Mycobacterium tuberculosis, lipid mediators, anti-tuberculosis treatment
Abstract

Background: Oxidized lipid mediators such as eicosanoids play a central role in the inflammatory response associated with tuberculosis (TB) pathogenesis. Diabetes mellitus (DM) leads to marked changes in lipid mediators in persons with TB. However, the associations between diabetes-related changes in lipid mediators and clearance of M. tuberculosis (Mtb) among persons on anti-TB treatment (ATT) are unknown. Quantification of urinary eicosanoid metabolites can provide insights into the circulating lipid mediators involved in Mtb immune responses. Methods: We conducted a multi-site prospective observational study among adults with drug-sensitive pulmonary TB and controls without active TB; both groups had sub-groups with or without dysglycemia at baseline. Participants were enrolled from RePORT-Brazil (Salvador site) and RePORT-South Africa (Durban site) and stratified according to TB status and baseline glycated hemoglobin levels: a) TB-dysglycemia (n=69); b) TB-normoglycemia (n=64); c) non-TB/dysglycemia (n=31); d) non-TB/non-dysglycemia (n=29). We evaluated the following urinary eicosanoid metabolites: 11α-hydroxy-9,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (major urinary metabolite of prostaglandin E2, PGE-M), tetranor-PGE1 (metabolite of PGE2, TN-E), 9α-hydroxy-11,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (metabolite of PGD2, PGD-M), 11-dehydro-thromboxane B2 (11dTxB2), 2,3-dinor-6-keto-PGF1α (prostaglandin I metabolite, PGI-M), and leukotriene E4 (LTE4). Comparisons between the study groups were performed at three time points: before ATT and 2 and 6 months after initiating therapy. Results: PGE-M and LTE4 values were consistently higher at all three time-points in the TB-dysglycemia group compared to the other groups (p

Published
2022

14. Are prognostic tools losing accuracy? Development and performance of a novel age-calibrated severity scoring system for critically ill patients

Author

Menezes, Rodrigo C., primary, Ferreira, Isabella B. B., additional, Carmo, Thomas A., additional, Telles, Gabriel P., additional, Pugas, Paula L. D., additional, Otero, Matheus L., additional, Arriaga, Maria B., additional, Fukutani, Kiyoshi F., additional, Neto, Licurgo P., additional, Agareno, Sydney, additional, Filgueiras Filho, Nivaldo M., additional, Akrami, Kevan M., additional, and Andrade, Bruno B., additional

Published
2020
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15. Systems Nutrology of Adolescents with Divergence between Measured and Perceived Weight Uncovers a Distinctive Profile Defined by Inverse Relationships of Food Consumption

Author

Andrade, Vanessa M. B., primary, Santana, Mônica L. P. de, additional, Fukutani, Kiyoshi F., additional, Queiroz, Artur T. L., additional, Arriaga, Maria B., additional, Damascena, Nadjane F., additional, Menezes, Rodrigo C., additional, Fernandes, Catarina D., additional, Conceição-Machado, Maria Ester P., additional, Silva, Rita de Cássia R., additional, and Andrade, Bruno B., additional

Published
2020
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16. Influence of body mass index on SAPS3 prognostic performance in critically ill patients from Brazil

Author

Ferreira, Isabella B. B., primary, Menezes, Rodrigo C., additional, Otero, Matheus L., additional, Carmo, Thomas A., additional, Telles, Gabriel P., additional, Fahel, Bruno V. B., additional, Barral-Netto, Manoel, additional, Arriaga, Maria B., additional, Fukutani, Kiyoshi F., additional, Neto, Licurgo Pamplona, additional, Agareno, Gabriel A., additional, Agareno, Sydney, additional, Akrami, Kevan M., additional, Filho, Nivaldo M.Filgueiras, additional, and Andrade, Bruno B., additional

Published
2020
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17. Derivation and Validation of a Novel Severity Scoring System for Pneumonia at Intensive Care Unit Admission

Author

Carmo, Thomas A, primary, Ferreira, Isabella B, additional, Menezes, Rodrigo C, additional, Telles, Gabriel P, additional, Otero, Matheus L, additional, Arriaga, Maria B, additional, Fukutani, Kiyoshi F, additional, Neto, Licurgo P, additional, Agareno, Sydney, additional, Filgueiras Filho, Nivaldo M, additional, Andrade, Bruno B, additional, and Akrami, Kevan M, additional

Published
2020
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18. Comparison of a modified Sequential Organ Failure Assessment Score using RASS and FOUR

Author

Telles, Gabriel Piñeiro, primary, Ferreira, Isabella Bonifácio Brige, additional, Carvalho de Menezes, Rodrigo, additional, do Carmo, Thomas Azevedo, additional, David Pugas, Paula Lins, additional, Marback, Lara Freitas, additional, Arriaga, Maria B., additional, Fukutani, Kiyoshi F., additional, Neto, Licurgo Pamplona, additional, Agareno, Sydney, additional, Akrami, Kevan M., additional, Filgueiras Filho, Nivaldo Menezes, additional, and Andrade, Bruno B., additional

Published
2020
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19. Immune Network Analysis Reveals Interleukin-17A Related Responses As Key Contributors to HIV-1 Associated Tuberculosis

Author

Du Bruyn, Elsa, primary, Fukutani, Kiyoshi F., additional, Rockwood, Neesha, additional, Schutz, Charlotte, additional, Meintjes, Graeme, additional, Arriaga, Maria B., additional, Cubillos-Angulo, Juan M., additional, Tibúrcio, Rafael, additional, Sher, Alan, additional, Riou, Catherine, additional, Wilkinson, Katalin A., additional, Andrade, Bruno B., additional, and Wilkinson, Robert J., additional

Published
2020
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20. Plasma levels of C-reactive protein, matrix metalloproteinase-7 and lipopolysaccharide-binding protein distinguish active pulmonary or extrapulmonary tuberculosis from uninfected controls in children

Author

Albuquerque, Victor V.S., primary, Kumar, Nathella Pavan, additional, Fukutani, Kiyoshi F., additional, Vasconcelos, Beatriz, additional, Arriaga, Maria B., additional, Silveira-Mattos, Paulo S., additional, Babu, Subash, additional, and Andrade, Bruno B., additional

Published
2019
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22. Derivation and Validation of a Novel Severity Scoring System for Pneumonia at Intensive Care Unit Admission.

Author

Carmo, Thomas A, Ferreira, Isabella B, Menezes, Rodrigo C, Telles, Gabriel P, Otero, Matheus L, Arriaga, Maria B, Fukutani, Kiyoshi F, Neto, Licurgo P, Agareno, Sydney, Filho, Nivaldo M Filgueiras, Andrade, Bruno B, and Akrami, Kevan M

Subjects
PNEUMONIA diagnosis, INTENSIVE care units, CRITICALLY ill, PATIENTS, SEVERITY of illness index, LONGITUDINAL method, EVALUATION
Abstract

Background Severity stratification scores developed in intensive care units (ICUs) are used in interventional studies to identify the most critically ill. Studies that evaluate accuracy of these scores in ICU patients admitted with pneumonia are lacking. This study aims to determine performance of severity scores as predictors of mortality in critically ill patients admitted with pneumonia. Methods Prospective cohort study in a general ICU in Brazil. ICU severity scores (Simplified Acute Physiology Score 3 [SAPS 3] and Sepsis-Related Organ Failure Assessment [qSOFA]), prognostic scores of pneumonia (CURB-65 [confusion, urea, respiratory rate, blood pressure, age] and CRB-65 [confusion, respiratory rate, blood pressure, age]), and clinical and epidemiological variables in the first 6 hours of hospitalization were analyzed. Results Two hundred patients were included between 2015 and 2018, with a median age of 81 years (interquartile range, 67–90 years) and female predominance (52%), primarily admitted from the emergency department (65%) with community-acquired pneumonia (CAP, 80.5%). SAPS 3, CURB-65, CRB-65,and qSOFA all exhibited poor performance in predicting mortality. Multivariate regression identified variables independently associated with mortality that were used to develop a novel pneumonia-specific ICU severity score (Pneumonia Shock score) that outperformed SAPS 3, CURB-65, and CRB-65. The Shock score was validated in an external multicenter cohort of critically ill patients admitted with CAP. Conclusions We created a parsimonious score that accurately identifies patients with pneumonia at highest risk of ICU death. These findings are critical to accurately stratify patients with severe pneumonia in therapeutic trials that aim to reduce mortality. [ABSTRACT FROM AUTHOR]

Published
2021
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