Search

Your search keyword '"Arriaga, María B."' showing total 190 results
Start Over Author "Arriaga, María B."
190 results on '"Arriaga, María B."'

2. An integrative multi-omics approach to characterize interactions between tuberculosis and diabetes mellitus

Author

Vinhaes, Caian L., Fukutani, Eduardo R., Santana, Gabriel C., Arriaga, María B., Barreto-Duarte, Beatriz, Araújo-Pereira, Mariana, Maggitti-Bezerril, Mateus, Andrade, Alice M.S., Figueiredo, Marina C., Milne, Ginger L., Rolla, Valeria C., Kristki, Afrânio L., Cordeiro-Santos, Marcelo, Sterling, Timothy R., Andrade, Bruno B., and Queiroz, Artur T.L.

Published
2024
Full Text
View/download PDF

3. Determinants of losses in the tuberculosis infection cascade of care among children and adolescent contacts of pulmonary tuberculosis cases: A Brazilian multi-centre longitudinal study

Author

Sobral, Luciana, Arriaga, María B., Souza, Alexandra B., Araújo-Pereira, Mariana, Barreto-Duarte, Beatriz, Sales, Caio, Rocha, Michael S., Benjamin, Aline, Moreira, Adriana S.R., de Oliveira, Jamile G., Carvalho, Anna Cristina, Spener-Gomes, Renata, Figueiredo, Marina C., Cavalcante, Solange, Durovni, Betina, Lapa-e-Silva, José R., Kritski, Afrânio L., Rolla, Valeria C., Sterling, Timothy R., Cordeiro-Santos, Marcelo, and Andrade, Bruno B.

Published
2022
Full Text
View/download PDF

6. Novel stepwise approach to assess representativeness of a large multicenter observational cohort of tuberculosis patients: The example of RePORT Brazil

Author

Arriaga, María B., Amorim, Gustavo, Queiroz, Artur T.L., Rodrigues, Moreno M.S., Araújo-Pereira, Mariana, Nogueira, Betania M.F., Souza, Alexandra Brito, Rocha, Michael S., Benjamin, Aline, Moreira, Adriana S.R., de Oliveira, Jamile G., Figueiredo, Marina C., Turner, Megan M., Alves, Kleydson, Durovni, Betina, Lapa-e-Silva, José R., Kritski, Afrânio L., Cavalcante, Solange, Rolla, Valeria C., Cordeiro-Santos, Marcelo, Sterling, Timothy R., and Andrade, Bruno B.

Published
2021
Full Text
View/download PDF

8. Polymorphisms in interferon pathway genes and risk of Mycobacterium tuberculosis infection in contacts of tuberculosis cases in Brazil

Author

Cubillos-Angulo, Juan Manuel, Arriaga, María B., Melo, Mayla G.M., Silva, Elisangela C., Alvarado-Arnez, Lucia Elena, de Almeida, Alexandre S., Moraes, Milton O., Moreira, Adriana S.R., Lapa e Silva, Jose R., Fukutani, Kiyoshi F., Sterling, Timothy R., Hawn, Thomas R., Kritski, Afrânio L., Oliveira, Martha M., and Andrade, Bruno B.

Published
2020
Full Text
View/download PDF

9. Influence of dietary pattern on anti-tuberculosis treatment outcomes in persons with dysglycemia: a Peruvian prospective cohort study

Author

Arriaga, María B., primary, Araújo-Pereira, Mariana, additional, Andrade, Vanessa M. B., additional, Queiroz, Artur T. L., additional, Fernandes, Catarina D., additional, Sales, Caio, additional, Aliaga, Juan Gonzalo, additional, Shivakoti, Rupak, additional, Lecca, Leonid, additional, Calderon, Roger I., additional, and Andrade, Bruno B., additional

Published
2023
Full Text
View/download PDF

11. Isoniazid Monoresistance and Antituberculosis Treatment Outcome in Persons With Pulmonary Tuberculosis in Brazil.

Author

Araújo-Pereira, Mariana, Arriaga, María B, Carvalho, Anna Cristina C, Spener-Gomes, Renata, Schmaltz, Carolina A S, Nogueira, Betânia M F, Figueiredo, Marina C, Turner, Megan M, Cordeiro-Santos, Marcelo, Rolla, Valeria C, Sterling, Timothy R, Andrade, Bruno B, Kritski, Afrânio L, and Consortium, for the Regional Prospective Observational Research for Tuberculosis (RePORT)-Brazil

Subjects
*TUBERCULOSIS, *ISONIAZID, *TREATMENT effectiveness, *LOGISTIC regression analysis, *ODDS ratio
Abstract

Background The high burden of drug-resistant tuberculosis (TB) is a problem to achieve the goals of the End TB Strategy by 2035. Whether isoniazid monoresistance (Hr) affects anti-TB treatment (ATT) outcomes remains unknown in high-burden countries. Methods We evaluated determinants of ATT outcome among pulmonary TB cases reported to the National Notifiable Disease Information System (SINAN) between June 2015 and June 2019, according to drug sensitivity testing (DST) results. Binomial logistic regression models were employed to evaluate whether Hr was associated with an unfavorable ATT outcome: death or failure, compared to cure or treatment completion. Results Among 60 804 TB cases reported in SINAN, 21 197 (34.9%) were included in the study. In this database, the frequency of unfavorable outcomes was significantly higher in those with Hr in contrast to isoniazid-sensitive persons with pulmonary TB (9.1% vs 3.05%; P <.001). Using a binomial logistic regression model, Hr was independently associated with unfavorable outcomes (odds ratio, 3.34 [95% confidence interval, 2.06–5.40]; P <.001). Conclusions Hr detected prior to ATT was predictive of unfavorable outcomes at the national level in Brazil. Our data reinforce the need for high-TB-burden countries to prioritize DST to detect Hr. Effective treatment regimens for Hr-TB are needed to improve outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

16. An Integrative Multi-Omics Approach to Characterize Interactions between Tuberculosis and Diabetes Mellitus

Author

Vinhaes, Caian L., primary, Fukutani, Eduardo R., additional, Santana, Gabriel C., additional, Arriaga, María B., additional, Barreto Duarte, Beatriz, additional, Araújo-Pereira, Mariana, additional, Maggitti-Bezerril, Mateus, additional, Andrade, Alice M. S., additional, Figueiredo, Marina C., additional, Milne, Ginger L., additional, Rolla, Valeria C., additional, Kritski, Afrânio L., additional, Cordeiro-Santos, Marcelo, additional, Sterling, Timothy R., additional, Andrade, Bruno B., additional, and Queiroz, Artur T. L., additional

Published
2023
Full Text
View/download PDF

17. Association between severe anaemia and inflammation, risk of IRIS and death in persons with HIV: A multinational cohort study

Author

Araújo-Pereira, Mariana, primary, Sheikh, Virginia, additional, Sereti, Irini, additional, Barreto-Duarte, Beatriz, additional, Arriaga, María B., additional, Tibúrcio, Rafael, additional, Vinhaes, Caian L., additional, Pinto-de-Almeida, Manuella, additional, Wang, Jing, additional, Rupert, Adam, additional, Roby, Gregg, additional, Shaffer, Douglas, additional, Ananworanich, Jintanat, additional, Phanuphak, Nittaya, additional, Sawe, Fred, additional, and Andrade, Bruno B., additional

Published
2022
Full Text
View/download PDF

18. Host-directed therapies in pulmonary tuberculosis: Updates on anti-inflammatory drugs

Author

Cubillos-Angulo, Juan M., primary, Nogueira, Betânia M. F., additional, Arriaga, María B., additional, Barreto-Duarte, Beatriz, additional, Araújo-Pereira, Mariana, additional, Fernandes, Catarina D., additional, Vinhaes, Caian L., additional, Villalva-Serra, Klauss, additional, Nunes, Vanessa M., additional, Miguez-Pinto, João P., additional, Amaral, Eduardo P., additional, and Andrade, Bruno B., additional

Published
2022
Full Text
View/download PDF

19. Tuberculosis treatment outcomes of diabetic and non-diabetic TB/HIV co-infected patients: A nationwide observational study in Brazil

Author

Villalva-Serra, Klauss, primary, Barreto-Duarte, Beatriz, additional, Nunes, Vanessa M., additional, Menezes, Rodrigo C., additional, Rodrigues, Moreno M. S., additional, Queiroz, Artur T. L., additional, Arriaga, María B., additional, Cordeiro-Santos, Marcelo, additional, Kritski, Afrânio L., additional, Sterling, Timothy R., additional, Araújo-Pereira, Mariana, additional, and Andrade, Bruno B., additional

Published
2022
Full Text
View/download PDF

20. Calibration and validation of the Pneumonia Shock Score in critically ill patients with SARS-CoV-2 infection, a multicenter prospective cohort study

Author

Carmo, Thomas A., primary, Ferreira, Isabella B. B., additional, Menezes, Rodrigo C., additional, Pina, Márcio L. T., additional, Oliveira, Roberto S., additional, Telles, Gabriel P., additional, Machado, Antônio F. A., additional, Aguiar, Tércio C., additional, Caldas, Juliana R., additional, Arriaga, María B., additional, Akrami, Kevan M., additional, Filgueiras Filho, Nivaldo M., additional, and Andrade, Bruno B., additional

Published
2022
Full Text
View/download PDF

21. A prospective comparison between multidisciplinary healthcare providers' clinical examination and a validated pain scale

Author

Menezes, Rodrigo C., primary, Silva, Raissa L. O., additional, Arriaga, María B., additional, Ferreira, Isabella B. B., additional, Carmo, Thomas A., additional, da Silva, Victor R., additional, Otero, Matheus L., additional, Gobatto, André L. N., additional, Agareno, Sydney, additional, Filgueiras Filho, Nivaldo M., additional, Akrami, Kevan M., additional, and Andrade, Bruno B., additional

Published
2022
Full Text
View/download PDF

22. Relationship Between Anemia and Systemic Inflammation in People Living With HIV and Tuberculosis: A Sub-Analysis of the CADIRIS Clinical Trial

Author

Araújo-Pereira, Mariana, primary, Barreto-Duarte, Beatriz, additional, Arriaga, María B., additional, Musselwhite, Laura W., additional, Vinhaes, Caian L., additional, Belaunzaran-Zamudio, Pablo F., additional, Rupert, Adam, additional, Montaner, Luis J., additional, Lederman, Michael M., additional, Sereti, Irini, additional, Madero, Juan G. Sierra, additional, and Andrade, Bruno B., additional

Published
2022
Full Text
View/download PDF

25. Tuberculosis treatment outcomes of diabetic and non-diabetic TB/HIV co-infected patients: A nationwide observational study in Brazil

Author

Villalva-Serra, Klauss, Barreto-Duarte, Beatriz, Nunes, Vanessa M., Menezes, Rodrigo C., Rodrigues, Moreno M. S., Queiroz, Artur T. L., Arriaga, María B., Cordeiro-Santos, Marcelo, Kritski, Afrânio L., Sterling, Timothy R., Araújo-Pereira, Mariana, and Andrade, Bruno B.

Subjects
tuberculosis, diabetes, treatment outcome, HIV, General Medicine, Antiretroviral therapy (ART)
Abstract

BackgroundTuberculosis (TB) is a worldwide public health problem, especially in countries that also report high numbers of people living with HIV (PLWH) and/or diabetes mellitus (DM). However, the unique features of persons with TB-HIV-DM are incompletely understood. This study compared anti-TB treatment (ATT) outcomes of diabetic and non-diabetic TB/HIV co-infected patients.MethodsA nationwide retrospective observational investigation was performed with data from the Brazilian Tuberculosis Database System among patients reported to have TB-HIV co-infection between 2014 and 2019. This database includes all reported TB cases in Brazil. Exploratory and association analyses compared TB treatment outcomes in DM and non-DM patients. Unfavorable outcomes were defined as death, treatment failure, loss to follow-up or recurrence. Multivariable stepwise logistic regressions were used to identify the variables associated with unfavorable ATT outcomes in the TB-HIV population.ResultsOf the 31,070 TB-HIV patients analyzed, 999 (3.2%) reported having DM. However, in these TB-HIV patients, DM was not associated with any unfavorable treatment outcome [adjusted Odds Ratio (aOR): 0.97, 95% CI: 0.83–1.12, p = 0.781]. Furthermore, DM was also not associated with any specific type of unfavorable outcome in this study. In both the TB-HIV group and the TB-HIV-DM subpopulation, use of alcohol, illicit drugs and tobacco, as well as non-white ethnicity and prior TB were all characteristics more frequently observed in persons who experienced an unfavorable ATT outcome.ConclusionDM is not associated with unfavorable TB treatment outcomes in persons with TB-HIV, including death, treatment failure, recurrence and loss to follow up. However, consumption habits, non-white ethnicity and prior TB are all more frequently detected in those with unfavorable outcomes in both TB-HIV and TB-HIV-DM patients.

Published
2022

27. Mycobacterium Tuberculosis Infection Among Child and Adolescent Contacts of Pulmonary Tuberculosis Cases in Brazil: A Multi-Center Prospective Cohort Study

Author

Sobral, Luciana, primary, Arriaga, María B., additional, Souza, Alexandra Brito, additional, Araújo-Pereira, Mariana, additional, Barreto Duarte, Beatriz, additional, Garcia-Rosa, Beatriz S., additional, Fernandes, Catarina D., additional, Sales, Caio, additional, Rocha, Michael S., additional, Benjamin, Aline, additional, Moreira, Adriana S. R., additional, de Oliveira, Jamile G., additional, Cristina, Anna C., additional, Spener-Gomes, Renata, additional, Figueiredo, Marina C., additional, Cavalcante, Solange, additional, Durovni, Betina, additional, Lapa-e-Silva, José R., additional, Kritski, Afranio L., additional, Rolla, Valeria C., additional, Sterling, Timothy R., additional, Cordeiro-Santos, Marcelo, additional, Andrade, Bruno B., additional, and Consortium, RePORT Brazil, additional

Published
2022
Full Text
View/download PDF

28. Determinants of Losses in the Tuberculosis Infection Cascade of Care Among Children and Adolescent Contacts of Pulmonary Tuberculosis Cases in Brazil

Author

Sobral, Luciana, primary, Arriaga, María B., additional, Souza, Alexandra Brito, additional, Araújo-Pereira, Mariana, additional, Barreto Duarte, Beatriz, additional, Sales, Caio, additional, Rocha, Michael S., additional, Benjamin, Aline, additional, Moreira, Adriana S. R., additional, de Oliveira, Jamile G., additional, Cristina, Anna C., additional, Spener-Gomes, Renata, additional, Figueiredo, Marina C., additional, Cavalcante, Solange, additional, Durovni, Betina, additional, Lapa-e-Silva, José R., additional, Kritski, Afranio L., additional, Rolla, Valeria C., additional, Sterling, Timothy R., additional, Cordeiro-Santos, Marcelo, additional, Andrade, Bruno B., additional, and Consortium, RePORT Brazil, additional

Published
2022
Full Text
View/download PDF

30. Factors Associated with Mortality in Critically Ill Patients Diagnosed with Hospital Acquired Infections [Erratum]

Author

Otero, Matheus L, primary, Menezes, Rodrigo C, additional, Ferreira, Isabella B B, additional, Issa, Francine L, additional, Agareno, Gabriel, additional, Carmo, Thomas Azevedo, additional, Arriaga, María B, additional, Fukutani, Kiyoshi F, additional, Pamplona Neto, Licurgo, additional, Agareno, Sydney, additional, Filgueiras Filho, Nivaldo M, additional, Akrami, Kevan M, additional, and Andrade, Bruno B, additional

Published
2021
Full Text
View/download PDF

32. Determinants of losses in the latent tuberculosis infection cascade of care in Brazil

Author

Souza, Alexandra Brito, primary, Arriaga, María B, additional, Amorim, Gustavo, additional, Araújo-Pereira, Mariana, additional, Nogueira, Betânia M F, additional, Queiroz, Artur T L, additional, Figueiredo, Marina C, additional, Rocha, Michael S, additional, Benjamin, Aline, additional, Moreira, Adriana S R, additional, Oliveira, Jamile G, additional, Rolla, Valeria, additional, Durovni, Betina, additional, Lapa e Silva, José R, additional, Kritski, Afrânio L, additional, Cavalcante, Solange, additional, Sterling, Timothy, additional, Andrade, Bruno B, additional, and Cordeiro-Santos, Marcelo, additional

Published
2021
Full Text
View/download PDF

33. Inflammatory profile of patients with tuberculosis with or without HIV-1 co-infection: a prospective cohort study and immunological network analysis

Author

Du Bruyn, Elsa, primary, Fukutani, Kiyoshi F, additional, Rockwood, Neesha, additional, Schutz, Charlotte, additional, Meintjes, Graeme, additional, Arriaga, María B, additional, Cubillos-Angulo, Juan M, additional, Tibúrcio, Rafael, additional, Sher, Alan, additional, Riou, Catherine, additional, Wilkinson, Katalin A, additional, Andrade, Bruno B, additional, and Wilkinson, Robert J, additional

Published
2021
Full Text
View/download PDF

34. Tuberculosis Burden and Determinants of Treatment Outcomes According to Age in Brazil: A Nationwide Study of 896,314 Cases Reported Between 2010 and 2019

Author

Barreto-Duarte, Beatriz, primary, Araújo-Pereira, Mariana, additional, Nogueira, Betânia M. F., additional, Sobral, Luciana, additional, Rodrigues, Moreno M. S., additional, Queiroz, Artur T. L., additional, Rocha, Michael S., additional, Nascimento, Vanessa, additional, Souza, Alexandra B., additional, Cordeiro-Santos, Marcelo, additional, Kritski, Afrânio L., additional, Sterling, Timothy R., additional, Arriaga, María B., additional, and Andrade, Bruno B., additional

Published
2021
Full Text
View/download PDF

39. Additional file 1 of The influence of single nucleotide polymorphisms of NOD2 or CD14 on the risk of Mycobacterium tuberculosis diseases: a systematic review

Author

Cubillos-Angulo, Juan M., Fernandes, Catarina D., Araújo, Davi N., Carmo, Cristinna A., Arriaga, María B., and Andrade, Bruno B.

Subjects
Hardware_MEMORYSTRUCTURES, InformationSystems_DATABASEMANAGEMENT
Abstract

Additional file 1. Table with the exact search strategy per database and the number of hits per database.

Published
2021
Full Text
View/download PDF

40. Effect of Dysglycemia on Urinary Lipid Mediator Profiles in Persons With Pulmonary Tuberculosis.

Author

Arriaga, María B., Karim, Farina, Queiroz, Artur T.L., Araújo-Pereira, Mariana, Barreto-Duarte, Beatriz, Sales, Caio, Moosa, Mahomed-Yunus S., Mazibuko, Matilda, Milne, Ginger L., Maruri, Fernanda, Henrique Serezani, Carlos, Koethe, John R., Figueiredo, Marina C., Kritski, Afrânio L., Cordeiro-Santos, Marcelo, Rolla, Valeria C., Sterling, Timothy R., Leslie, Alasdair, and Andrade, Bruno B.

Abstract

Background: Oxidized lipid mediators such as eicosanoids play a central role in the inflammatory response associated with tuberculosis (TB) pathogenesis. Diabetes mellitus (DM) leads to marked changes in lipid mediators in persons with TB. However, the associations between diabetes-related changes in lipid mediators and clearance of M. tuberculosis (Mtb) among persons on anti-TB treatment (ATT) are unknown. Quantification of urinary eicosanoid metabolites can provide insights into the circulating lipid mediators involved in Mtb immune responses. Methods: We conducted a multi-site prospective observational study among adults with drug-sensitive pulmonary TB and controls without active TB; both groups had subgroups with or without dysglycemia at baseline. Participants were enrolled from RePORTBrazil (Salvador site) and RePORT-South Africa (Durban site) and stratified according to TB status and baseline glycated hemoglobin levels: a) TB-dysglycemia (n=69); b) TBnormoglycemia (n=64); c) non-TB/dysglycemia (n=31); d) non-TB/non-dysglycemia (n=29). We evaluated the following urinary eicosanoid metabolites: 11α-hydroxy-9,15- dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (major urinary metabolite of prostaglandin E2, PGE-M), tetranor-PGE1 (metabolite of PGE2, TN-E), 9α-hydroxy11,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (metabolite of PGD2, PGD-M), 11-dehydro-thromboxane B2 (11dTxB2), 2,3-dinor-6-keto-PGF1α (prostaglandin I metabolite, PGI-M), and leukotriene E4 (LTE4). Comparisons between the study groups were performed at three time points: before ATT and 2 and 6 months after initiating therapy. Results: PGE-M and LTE4 values were consistently higher at all three time-points in the TB-dysglycemia group compared to the other groups (p<0.001). In addition, there was a significant decrease in PGI-M and LTE4 levels from baseline to month 6 in the TBdysglycemia and TB-normoglycemia groups. Finally, TB-dysglycemia was independently associated with increased concentrations of PGD-M, PGI-M, and LTE4 at baseline in a multivariable model adjusting for age, sex, BMI, and study site. These associations were not affected by HIV status. Conclusion: The urinary eicosanoid metabolite profile was associated with TBdysglycemia before and during ATT. These observations can help identify the mechanisms involved in the pathogenesis of TB-dysglycemia, and potential biomarkers of TB treatment outcomes, including among persons with dysglycemia. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

41. Divergence in Accuracy of Diabetes Screening Methods in Tuberculosis Patients: A Cross- Sectional Study from Brazil and Peru

Author

Carmo, Thomas A., primary, Fernandes, Catarina D., additional, Neto, José F. Fróes, additional, Araújo, Davi Neri, additional, Vinhaes, Caian L., additional, Cubillos-Angulo, Juan M., additional, Nogueira, Betânia M. F., additional, Rocha, Michael S., additional, Nascimento, Vanessa, additional, Calderon, Roger I., additional, Lecca, Leonid, additional, Netto, Eduardo M., additional, Andrade, Bruno B., additional, and Arriaga, María B., additional

Published
2021
Full Text
View/download PDF

42. The Effect of Diabetes and Prediabetes on Mycobacterium tuberculosis Transmission to Close Contacts

Author

Arriaga, María B, primary, Rocha, Michael S, additional, Nogueira, Betânia M F, additional, Nascimento, Vanessa, additional, Araújo-Pereira, Mariana, additional, Souza, Alexandra B, additional, Andrade, Alice M S, additional, Costa, Alysson G, additional, Gomes-Silva, Adriano, additional, Silva, Elisangela C, additional, Figueiredo, Marina C, additional, Turner, Megan M, additional, Durovni, Betina, additional, Lapa-e-Silva, José R, additional, Kritski, Afrânio L, additional, Cavalcante, Solange, additional, Rolla, Valeria C, additional, Cordeiro-Santos, Marcelo, additional, Sterling, Timothy R, additional, and Andrade, Bruno B, additional

Published
2021
Full Text
View/download PDF

43. Clinical and Biochemical Features of Hypopituitarism Among Brazilian Children With Zika Virus–Induced Microcephaly

Author

Ferreira, Leda L., primary, Aguilar Ticona, Juan P., additional, Silveira-Mattos, Paulo S., additional, Arriaga, María B., additional, Moscato, Thaisa B., additional, Conceição, Gildásio C., additional, Santos, Antonio Carlos dos, additional, Costa, Federico, additional, Alves, Crésio A.D., additional, and Antonini, Sonir R., additional

Published
2021
Full Text
View/download PDF

44. The Effect of Diabetes and Prediabetes on Anti-tuberculosis Treatment Outcomes: A Multicentric Prospective Cohort Study

Author

Arriaga, María B., primary, Araújo-Pereira, Mariana, additional, Barreto-Duarte, Beatriz, additional, Nogueira, Betânia, additional, Freire, Maria Vitória C.N.S., additional, Queiroz, Artur T.L., additional, Rodrigues, Moreno M.S., additional, Rocha, Michael S., additional, Souza, Alexandra B., additional, Spener-Gomes, Renata, additional, Carvalho, Anna Cristina C., additional, Figueiredo, Marina C., additional, Turner, Megan M., additional, Durovni, Betina, additional, Lapa-e-Silva, José R., additional, Kritski, Afrânio L., additional, Cavalcante, Solange, additional, Rolla, Valeria C., additional, Cordeiro-Santos, Marcelo, additional, Sterling, Timothy R., additional, and Andrade, Bruno B., additional

Published
2021
Full Text
View/download PDF

45. Dysglycemia is associated with Mycobacterium tuberculosis lineages in tuberculosis patients of North Lima—Peru

Author

Lopez, Kattya, primary, Arriaga, María B., additional, Aliaga, Juan G., additional, Barreda, Nadia N., additional, Sanabria, Oswaldo M., additional, Huang, Chuan-Chin, additional, Zhang, Zibiao, additional, García-de-la-Guarda, Ruth, additional, Lecca, Leonid, additional, Calçada Carvalho, Anna Cristina, additional, Kritski, Afrânio L., additional, and Calderon, Roger I., additional

Published
2021
Full Text
View/download PDF

47. How Well Do Intensive Care Teams Assess Pain? Prospective Evaluation of the Correlation between Pain Assessments by the Health Professionals and a Validated Scale

Author

Silva, Raissa L. O., primary, Arriaga, María B., additional, Menezes, Rodrigo C., additional, Ferreira, Isabella B. B., additional, Carmo, Thomas A., additional, Otero, Matheus L., additional, da Silva, Victor R., additional, Gobatto, André L. N., additional, Agareno, Sydney, additional, Akrami, Kevan M., additional, Filgueiras Filho, Nivaldo M., additional, and Andrade, Bruno B., additional

Published
2021
Full Text
View/download PDF

48. Tuberculosis Burden and Determinants of Treatment Outcomes According to Age in Brazil: A Nationwide Ecological Study of 896,314 Cases Reported between 2010 and 2019

Author

Barreto Duarte, Beatriz, primary, Araújo-Pereira, Mariana, additional, Nogueira, Betania M. F., additional, Sobral, Luciana, additional, Rodrigues, Moreno M. S., additional, Queiroz, Artur T. L., additional, Rocha, Michael S., additional, Nascimento, Vanessa, additional, Souza, Alexandra Brito, additional, Cordeiro-Santos, Marcelo, additional, Kritski, Afranio L., additional, Sterling, Timothy R., additional, Arriaga, María B., additional, and Andrade, Bruno B., additional

Published
2021
Full Text
View/download PDF

49. Factors Associated with Mortality in Critically Ill Patients Diagnosed with Hospital Acquired Infections

Author

Otero, Matheus L, Menezes, Rodrigo C, Ferreira, Isabella B B, Issa, Francine L, Agareno, Gabriel, Carmo, Thomas Azevedo, Arriaga, María B, Fukutani, Kiyoshi F, Pamplona Neto, Licurgo, Agareno, Sydney, Filgueiras Filho, Nivaldo M, Akrami, Kevan M, and Andrade, Bruno B

Subjects
Infection and Drug Resistance, ICU, critical illness, septic shock, mortality, Original Research, hospital acquired infection, intensive care
Abstract

Matheus L Otero,1 Rodrigo C Menezes,2 Isabella B B Ferreira,3 Francine L Issa,4 Gabriel Agareno,1 Thomas Azevedo Carmo,1 María B Arriaga,4– 6 Kiyoshi F Fukutani,5,6 Licurgo Pamplona Neto,7 Sydney Agareno,7 Nivaldo M Filgueiras Filho,1,3,7,* Kevan M Akrami,8,* Bruno B Andrade1,4– 6,9,* 1Curso de Medicina, Universidade Salvador (UNIFACS), Laureate Universities, Salvador, Bahia, Brazil; 2Curso de Medicina, União Metropolitana Para o Desenvolvimento da Educação e Cultura (UNIME), Salvador, Bahia, Brazil; 3Universidade Do Estado Da Bahia (UNEB), Salvador, Bahia, Brazil; 4Curso de Medicina, Universidade do Estado da Bahia, Salvador, Bahia, Brazil; 5Laboratório de Inflamação e Biomarcadores, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Bahia, Brazil; 6Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil; 7Hospital Da Cidade, Intensive Care Unit, Salvador, Bahia, Brazil; 8Division of Infectious Diseases and Pulmonary Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, California, USA; 9Escola Bahiana De Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil*These authors contributed equally to this workCorrespondence: Bruno B AndradeLaboratório De Inflamação e Biomarcadores, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão No. 121, Candeal, Salvador, Bahia 40269-710, BrazilEmail bruno.andrade@fiocruz.brObjective: Evaluate host and pathogen factors associated with mortality in those with hospital acquired infections (HAI) in a tertiary intensive care unit in Brazil.Methods: Observational and analytical cohort single center study in a general intensive care unit (ICU) in Northeastern Brazil between January 2016 and August 2018, including those over 18 years of age admitted to the ICU found to have a HAI.Results: A total of 165 patients were included, with a mean age of 72 years and male predominance (53.3%) and observed mortality of 46%. Mortality in those with HAI was significantly associated with older age, increased ICU length of stay and readmission to the ICU in univariate analysis. Multivariate analysis revealed that development of septic shock and obtundation during ICU admission was significantly associated with an increased risk of death (OR: 6.94, 95% CI 1.23– 39.27, OR: 2.48, 95% CI 1.17– 5.29, respectively). A trend towards mortality risk was noted in those with increased age and prior cardiovascular disease. Surprisingly, mortality risk was independent of site of infection, type of pathogen and antibiotic resistance. Furthermore, having more than one HAI over the course of the ICU admission did not impact mortality.Conclusion: Risk of death in those with HAI is associated with obtundation and septic shock, in addition to vasopressor use. Host factors, rather than pathogen-specific characteristics or infecting site, impact risk of death related to HAI in the ICU.Keywords: hospital acquired infection, ICU, mortality, critical illness, septic shock, intensive care

Published
2020

50. Dysglycemia is associated withMycobacterium tuberculosislineages in tuberculosis patients of North Lima - Peru

Author

Lopez, Kattya, primary, Arriaga, María B., additional, Aliaga, Juan G., additional, Barreda, Nadia N., additional, Sanabria, Oswaldo M., additional, Huang, Chuan-Chin, additional, Zhang, Zibiao, additional, García-de-la-Guarda, Ruth, additional, Lecca, Leonid, additional, Calçada Carvalho, Anna Cristina, additional, Kritski, Afrânio L., additional, and Calderon, Roger I., additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results