Search

Your search keyword '"Arnedillo Muñoz, A"' showing total 139 results
Start Over Author "Arnedillo Muñoz, A"
139 results on '"Arnedillo Muñoz, A"'

1. Actualidad y planes de acción en el desarrollo de la neumología y cirugía torácica española

Author

Jiménez-Ruiz, Carlos A., Peces-Barba, Germán, Diego Roza, Carmen, Valido Morales, Agustin, Gea, Joaquin, Perez Chica, Gerardo, Solano Reina, Segismundo, Moreno Balsalobre, Ramon, Salas Llinas, Ernest, Garcia Clemente, Marta María, Mañes Bonet, Nuria, Rodriguez Nieto, María Jesús, Arnedillo Muñoz, Aurelio, Martin de Carpi, Teresa, Sánchez de Cos Escuin, Julio, Estrada Trigueros, Graciliano, Godoy Mayoral, Raúl, Barbeta Sánchez, Enric, Marcos Rodriguez, Pedro Jorge, Ros Lucas, Jose Antonio, Martinez Moragón, Eva, and Tomás López, Laura

Published
2020
Full Text
View/download PDF

2. Factores que condicionan la pérdida de control al reducir escalones terapéuticos en el tratamiento del asma moderada-grave en la práctica clínica habitual: estudio español multicéntrico

Author

Martínez-Moragón, E., Delgado, J., Mogrovejo, S., Fernández-Sánchez, T., Jesús, Jiménez López, Ángel, Moscardó Orenes Miguel, Patricia, Prieto Montaño, Miguel, Torrecillas Toro, Begoña, Cueva Oliver, Ángel, Ferrer Torres, Purificación, González Delgado, Wilfox, Jiménez Rodríguez Teodorikez, Brian, Vila Auli, José, Zapata Yebenes Juan, Teresa, Audicana Berasategui María, Marta, Frias Jiménez, Nieves, Hurtado de Mendoza Ruibio, Marta, Velasco Azagra, Antonio, Álvarez Fernández Jose, Sara, Acero Sainz, Rosa, Blanco González M., Estela, Gómez Nieves María, Diego, Aisa Carpio, Núria, Angrill Sellés, Cristina, Berastegui García, Astrid, Crespo Lessmann, David, De La Rosa Carrillo, Jordi, Juanola Pla, Alejandra, López Giraldo, Olga, Luengo Sánchez, Carlos, Martínez Rivera, Pilar, Martínez Olondris, Xavier, Muñoz Gall, Ester, Pinto Nogués, Francisco, Planas Coimerma, Karina, Portillo Carroz, Antoni, Riba Blanch, Luisa, Rivera Ortún M., Dan, Sánchez Berenguer, Joan, Serra Batlles, Pere, Serra Mitjà, Ana, Sogo Sagardía, Lorena, Soto Retes, Joan, Valldeperas Combas, Xavier, Vila Giralte, Ignacio, Ansotegui Zubeldia, Ignacio, Antepara Ercoreca, Miguel, Herrerías Peña, Milagros, Iriberri Pascual María, Carmen, Jaca Michelena, Adolfo, Lahuerta Castro, Amaia, Laita Legarreta, Paula, Losada Llorente, Joaquina, Prieto Prieto, Vanessa, Zorrilla Lorenzo, Lidia, Alonso Gil, Pablo, García Muñoz Juan, Marisa, Marcos Durantez, Teresa, Peña Miguel, Tahar, Ahmida, Isabel, Alvarado Izquierdo María, Michael, Alwakil Olbah, Aurelio, Arnedillo Muñoz, Ignacio, García Núñez, Diego, Gutiérrez Fernández, Antonio, Letran Camacho, Luis, Fernández Pellon, Maria, Morchon Miguel Eva, Félix, Ortiz Portal, Isabela, Raducan, Antonio, Royo Prats Juan, Dolores, Salvador Segarra María, Frederic, Tatay Soler, Alberto, Levy Naon, Pedro, Galindo Bonilla, Luis, Gil Muñoz Francisco, Patricia, Mata Calderón, Manuel, Entrenas Costa Luis, Marina, Blanco Aparicio, Manuel, García Pazos Jose, Vanessa, García Paz, Francisco-Javier, González Barcala, Pilar, Iriarte Sotes, Jorge, Marcos Rodríguez Pedro, Fernando, Molina Nieto, Ramón, Nuñez Orjales, Carracedo, Sevillano Martín, Juan, Suárez Antelo, Julia, Tábara Rodríguez, Santiago, Aparicio Español, Carlos, Sabadell Nieto, Gladis, Sabater Talaverano, Mar, Escribano Rodríguez M., Fernando, Florido López José, Ángeles, Lara Jiménez María, José, Rojas Vílchez María, Susana, Chic Palacín, Silvia, Dorronsoro Quintana, Antonio, Navarro Echeverria Jose, Eduardo, Figueroa de la Guardia, Belén, Hinojosa Jara, Victoria, Moreno García, Lucía, Valverde Vazquez, Joaquín, Cegoñino de Sus, Santonio, Compaired Villa Jose, Alfonso, Almagro López Juan, Eduardo, Arcalá Campillo, María, Cruz Molina Jose, Dolores, Soto Venegas Antonia, Patricia, Benito Martínez, Begoña, Blanco Reinosa, Beatriz, Fernández Parra, Domingo, Fernández García, Virginia, Serrano Gutiérrez, Adolfo, Velez Ruiz de Lobera, Silvia, Lara Alcon, Francisco, Carballada González, Teresa, González Fernández, Joaquín, Martín Lázaro, Noemí, Mengual Macenlle, Soledad, Alonso Viteri, Darío, Antolín Amerigo, Irina, Bobolea, Puerto, Cano Aguirre M. del, Remedios, Cardenas Contreras, Fernando, Carrillo Arias, Mercedes, Cimarra Álvarez, Belén, De Higes Martínez Eva, Magdalena, Díaz Campos Rocío, Mar, Gandolfo Cano María del, Leticia, García Rodríguez, Andrés, García Romero de Tejada Jose, Eloina, González Mancebo, Emma, González Seco, Fernando, González Torralba, Aythamy, Henríquez Santana, Lys, Herráez Herrera Pilar de, Ruth, Herrero Mosquete María, Pedro, Landete Rodríguez, Belén, López-Muñiz Ballesteros, Ester, Mohedano Vicente, Beatriz, Morales Chacón, Antonio, Moreno Fernández, Esther, Muñoz García, Elena, Ojeda Castillejo, Fernando, Pedraza Serrano, Yesenia, Peña Acevedo Acevedo, Raquel, Pérez Rojo, Natividad, Quílez Ruiz-Rico, Ángela, Ramos Pinedo, Beatriz, Rodríguez Jiménez, Mercedes, Rodríguez Rodríguez, Ana, Rosado Ingelmo, Antonio, Ruiz Peña, José, Sánchez González María, Jesús, Trujillo Trujillo María, Laura, Vázquez Fuertes, Concepción, Vila Albelda, Alexandra, Yago Meniz, Ismael, Aguilar Perez Grovas Ricardo, José, Alcázar Ramírez Alcázar Ramírez, Manuel, Barceló Muñoz José, Miguel, Bentabol Manzanares, Gustavo, De Luiz Martínez, Francisco, Linde de Luna, Alfonso, Miranda Paez, Ezequiel, Ortega Sáenz de Tejada, Alicia, Padilla Galo, Manuel, Pérez Estrada Cornejo, Carmen, Soria Esojo, Francisco, Abellán Alemán Ángel, Consuelo, Alcalde Rumayor María, Rubén, Andújar Espinosa, Roberto, Bernabeu Mora, Javier, Campano Lancharro Francisco, Tamara, Gutiérrez Urra, Sonia, Herrero Martín, Alfredo, Resano Lizaldre, and Raquel, Dacal Quintas

Published
2020
Full Text
View/download PDF

3. Aspectos claves de la Neumología y la Cirugía Torácica sometidos a debate en la era COVID-19

Author

Carlos A. Jiménez-Ruiz, Agustin Valido Morales, Gerardo Perez Chica, Isabel Urrutia Landa, Jose Antonio Rodriguez Portal, Aurelio Arnedillo Muñoz, Fernando Cózar Bernal, Germán Peces-Barba, Carmen Diego Roza, Segismundo Solano Reina, Pedro Rodriguez Suarez, Francisco Garcia Rio, Ernest Salas Llinas, Marta María Garcia Clemente, Jose Manuel Valencia Gallardo, María Jesús Rodriguez Nieto, Teresa Martin de Carpi, Julio Sánchez de Cos Escuin, Graciliano Estrada Trigueros, Raúl Godoy Mayoral, Enric Barbeta Sánchez, Alberto Fernández Villar, Jose Antonio Ros Lucas, Eva Martinez Moragón, and Laura Tomás López

Subjects
Diseases of the respiratory system, RC705-779
Published
2021
Full Text
View/download PDF

4. Reply to Yigit, S.; Akinci, B. Comment on “Vázquez-Gandullo et al. Inspiratory Muscle Training in Patients with Chronic Obstructive Pulmonary Disease (COPD) as Part of a Respiratory Rehabilitation Program Implementation of Mechanical Devices: A Systematic Review. Int. J. Environ. Res. Public Health 2022, 19, 5564”

Author

Vázquez-Gandullo, Eva, primary, Hidalgo-Molina, Antonio, additional, Montoro-Ballesteros, Francisca, additional, Morales-González, María, additional, Muñoz-Ramírez, Isabel, additional, and Arnedillo-Muñoz, Aurelio, additional

Published
2023
Full Text
View/download PDF

11. Inspiratory Muscle Training in Patients with Chronic Obstructive Pulmonary Disease (COPD) as Part of a Respiratory Rehabilitation Program Implementation of Mechanical Devices: A Systematic Review

Author

Eva Vázquez-Gandullo, Antonio Hidalgo-Molina, Francisca Montoro-Ballesteros, María Morales-González, Isabel Muñoz-Ramírez, and Aurelio Arnedillo-Muñoz

Subjects
Pulmonary Disease, Chronic Obstructive, inspiratory muscle training, Exercise Tolerance, quality of life, respiratory rehabilitation, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, Quality of Life, inspiratory restriction device, Humans, Breathing Exercises, Respiratory Muscles, chronic obstructive pulmonary disease
Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a complex and heterogeneous disease, with pulmonary and extrapulmonary manifestations, which leads to the need to personalize the assessment and treatment of these patients. The latest updates of national and international guidelines for the management of COPD reveal the importance of respiratory rehabilitation (RR) and its role in improving symptoms, quality of life, and psychosocial sphere of patients. Within RR, the inspiratory muscle training (IMT) has received special interest, showing benefits in maximum inspiratory pressure, perception of well-being, and health status in patients with chronic heart disease, respiratory diseases, and dyspnea during exercise. The aim of this review is to assess the efficacy of IMT in COPD patients through the use of inspiratory muscle training devices, compared with respiratory rehabilitation programs without inspiratory muscle training. In the last years, many mechanical devices focused on inspiratory muscle training have been developed, some of them, such as the AirOFit PRO™, PowerBreath®, or FeelBreathe®, have shown clear benefits. The active search for candidate patients to undergo the RR program with inspiratory muscle training using this type of device in COPD patients represents an advance in the treatment of this disease, with direct benefits on the quality of life of the patients. In this article, we review the available evidence on IMT in these patients and describe the different devices used for it.

Published
2022

15. Actualidad y planes de acción en el desarrollo de la neumología y cirugía torácica española

Author

Graciliano Estrada Trigueros, Segismundo Solano Reina, Agustín Salvador Valido Morales, Raúl Godoy Mayoral, Carlos A. Jiménez-Ruiz, Julio Sánchez de Cos Escuín, Laura Tomás López, Carmen Diego Roza, Germán Peces-Barba, Joaquin Gea, Jose Antonio Ros Lucas, Nuria Mañes Bonet, Pedro Jorge Marcos Rodríguez, Ramon Moreno Balsalobre, Gerardo Perez Chica, Marta María Garcia Clemente, Eva Martinez Moragón, Ernest Salas Llinas, Aurelio Arnedillo Muñoz, María Jesús Rodriguez Nieto, Teresa Martin de Carpi, and Enric Barbeta Sánchez

Subjects
lcsh:RC705-779, Thoracic surgery, Pulmonology, lcsh:Diseases of the respiratory system, Activities, Management
Abstract

Resumen: Se ha comprobado que los temas de actualidad y los puntos claves para el desarrollo de la neumología y cirugía torácica son comunes independientemente de la comunidad autónoma valorada, aunque con realidades bien distintas a la hora de afrontarlos. Esto hace que este tipo de foros, además de enriquecedores al poner de manifiesto las diferencias territoriales existentes, sean necesarios para diseñar estrategias de futuro comunes que puedan ser lideradas desde SEPAR a nivel nacional. Abstract: Current issues and key points in the development of pulmonology and thoracic surgery are the same among the different autonomous communities of Spain, although each community takes a very different approach in addressing these issues. As a result, forums that shed light on territorial differences are not only informative, but are also essential for designing common SEPAR-led strategies for the future at a countrywide level.

Published
2020

16. Factors that determine the loss of control when reducing therapy by steps in the treatment of moderate-severe asthma in standard clinical practice: A multicentre Spanish study

Author

Zapata Yebenes Juan José, Vila Auli Brian, González Delgado Purificación, Hurtado de Mendoza Ruibio Nieves, Vila Giralte Xavier, Florido López José Fernando, Mata Calderón Patricia, De Higes Martínez Eva Belén, Almagro López Juan Alfonso, Peña Acevedo Acevedo Yesenia, Carballada González Francisco, Jiménez López Jesús, Navarro Echeverria Jose Antonio, Compaired Villa Jose Santonio, Levy Naon Alberto, Losada Llorente Paula, Martínez Olondris Pilar, Moreno García Victoria, Mohedano Vicente Ester, Barceló Muñoz José Manuel, Alonso Viteri Soledad, Alonso Gil Lidia, Aguilar Perez Grovas Ricardo Ismael, Jaca Michelena Carmen, en nombre del grupo de investigación Step, García Pazos Jose Manuel, Dacal Quintas Raquel, Cimarra Álvarez Mercedes, Salvador Segarra María Dolores, Torrecillas Toro Miguel, Gutiérrez Fernández Diego, Iriarte Sotes Pilar, Serra Mitjà Pere, López Giraldo Alejandra, Sabater Talaverano Gladis, Berastegui García Cristina, Álvarez Fernández Jose Antonio, Raducan Isabela, Hinojosa Jara Belén, Blanco Aparicio Marina, Rivera Ortún M. Luisa, Sogo Sagardía Ana, Cegoñino de Sus Joaquín, Pérez Rojo Raquel, Prieto Montaño Patricia, García Romero de Tejada Jose Andrés, Soto Venegas Antonia Dolores, García Paz Vanessa, Dorronsoro Quintana Silvia, S. Mogrovejo, Valverde Vazquez Lucía, Peña Miguel Teresa, Fernández García Domingo, Serrano Gutiérrez Virginia, Moscardó Orenes Miguel Ángel, Rosado Ingelmo Ana, Sabadell Nieto Carlos, Lara Jiménez María Ángeles, Ortega Sáenz de Tejada Ezequiel, Molina Nieto Fernando, Soto Retes Lorena, Mengual Macenlle Noemí, Rodríguez Jiménez Beatriz, Gandolfo Cano María del Mar, Antolín Amerigo Darío, Chic Palacín Susana, Acero Sainz Sara, Herrero Mosquete María Ruth, Moreno Fernández Antonio, Entrenas Costa Luis Manuel, Lara Alcon Silvia, Sánchez González María José, Cardenas Contreras Remedios, González Mancebo Eloina, Rojas Vílchez María José, Zorrilla Lorenzo Vanessa, Rodríguez Rodríguez Mercedes, González Barcala Francisco-Javier, Vázquez Fuertes Laura, De La Rosa Carrillo David, Alwakil Olbah Michael, Galindo Bonilla Pedro, Campano Lancharro Francisco Javier, Fernández Pellon Luis, Fernández Parra Beatriz, Quílez Ruiz-Rico Natividad, Herrerías Peña Miguel, Benito Martínez Patricia, Pérez Estrada Cornejo Manuel, Aparicio Español Santiago, Velasco Azagra Marta, Arcalá Campillo Eduardo, Alcalde Rumayor María Consuelo, Aisa Carpio Diego, Miranda Paez Alfonso, Tatay Soler Frederic, Sevillano Martín Carracedo, Gómez Nieves María Estela, González Seco Emma, De Luiz Martínez Gustavo, Planas Coimerma Francisco, Angrill Sellés Núria, Cruz Molina Jose María, Soria Esojo Carmen, Bentabol Manzanares Miguel, Blanco Reinosa Begoña, Martínez Rivera Carlos, Ansotegui Zubeldia Ignacio, Audicana Berasategui María Teresa, Iriberri Pascual María Milagros, Alvarado Izquierdo María Isabel, Valldeperas Combas Joan, Herráez Herrera Pilar de Lys, Velez Ruiz de Lobera Adolfo, González Fernández Teresa, Blanco González M. Rosa, Marcos Durantez Marisa, Linde de Luna Francisco, Letran Camacho Antonio, Bernabeu Mora Roberto, Sánchez Berenguer Dan, Muñoz García Esther, Jiménez Rodríguez Teodorikez Wilfox, Padilla Galo Alicia, García Muñoz Juan Pablo, Arnedillo Muñoz Aurelio, Vila Albelda Concepción, Figueroa de la Guardia Eduardo, Laita Legarreta Amaia, Andújar Espinosa Rubén, Crespo Lessmann Astrid, T. Fernández-Sánchez, J. Delgado, Abellán Alemán Ángel Francisco, Escribano Rodríguez M. Mar, Resano Lizaldre Alfredo, Portillo Carroz Karina, Yago Meniz Alexandra, Riba Blanch Antoni, Martín Lázaro Joaquín, Ortiz Portal Félix, Frias Jiménez Marta, Royo Prats Juan Antonio, Pedraza Serrano Fernando, Pinto Nogués Ester, Díaz Campos Rocío Magdalena, Luengo Sánchez Olga, Serra Batlles Joan, Bobolea Irina, Ojeda Castillejo Elena, González Torralba Fernando, E. Martínez-Moragón, Ruiz Peña Antonio, Alcázar Ramírez Alcázar Ramírez José, Nuñez Orjales Ramón, Trujillo Trujillo María Jesús, Gil Muñoz Francisco Luis, Morales Chacón Beatriz, Morchon Miguel Eva Maria, Carrillo Arias Fernando, García Núñez Ignacio, Ramos Pinedo Ángela, Gutiérrez Urra Tamara, Ahmida Tahar, Marcos Rodríguez Pedro Jorge, Henríquez Santana Aythamy, Landete Rodríguez Pedro, Suárez Antelo Juan, García Rodríguez Leticia, Cano Aguirre M. del Puerto, López-Muñiz Ballesteros Belén, Juanola Pla Jordi, Muñoz Gall Xavier, Antepara Ercoreca Ignacio, Tábara Rodríguez Julia, Ferrer Torres Ángel, Herrero Martín Sonia, Prieto Prieto Joaquina, Cueva Oliver Begoña, and Lahuerta Castro Adolfo

Subjects
medicine.medical_specialty, business.industry, Severe asthma, Asthma treatment, Retrospective cohort study, General Medicine, medicine.disease, Disease control, Clinical Practice, 03 medical and health sciences, 0302 clinical medicine, Patient age, Internal medicine, medicine, 030212 general & internal medicine, Severity level, business, Asthma
Abstract

Although the clinical practice guidelines recommend continuous adjustment of asthma treatment and reducing the maintenance drugs when achieving control (step-down), there are few studies of standard clinical practice aimed at collecting information on the factors that determine step-down failure.To determine the factors that determine step-down failure in standard clinical practice of patients with moderate-severe asthma controlled by a combination of inhaled glucocorticoids and long-acting beta agonists.A multicentre retrospective study included 374 patients with moderate-severe asthma controlled with inhaled glucocorticoids and long-acting beta agonists for whom the physician indicated a step-down in 2016.The step-down failed in 41.7% of the patients. The following factors were related to failure: greater patient age (P=.006), presence of at least 2 comorbidities (P=.016), greater severity level (severe persistent vs. moderate persistent) (P.001), greater age at diagnosis (40 years) (P=.045), the higher the therapeutic step before (P=.003) and after the change (P.001), the shorter the time of improvement/control prior to the change (P=.019), lower FEVIn standard clinical practice conditions, step-down fails in a high percentage of patients, and the suggestion is to indicate step-down when the patient has had more than 6 months of disease control.

Published
2020
Full Text
View/download PDF

17. Reply to Yigit, S.; Akinci, B. Comment on 'Vázquez-Gandullo et al. Inspiratory Muscle Training in Patients with Chronic Obstructive Pulmonary Disease (COPD) as Part of a Respiratory Rehabilitation Program Implementation of Mechanical Devices: A Systematic Review. Int. J. Environ. Res. Public Health 2022, 19, 5564'

Author

Eva Vázquez-Gandullo, Antonio Hidalgo-Molina, Francisca Montoro-Ballesteros, María Morales-González, Isabel Muñoz-Ramírez, and Aurelio Arnedillo-Muñoz

Subjects
Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health
Abstract

We would like to thank you for your interest [...]

Published
2023
Full Text
View/download PDF

18. Exercise Capacity and Physical Activity in Non-Cystic Fibrosis Bronchiectasis after a Pulmonary Rehabilitation Home-Based Programme: A Randomised Controlled Trial

Author

Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Fisioterapia, Cedeño de Jesús, Sindy, Almadana Pacheco, Virginia, Valido-Morales, Agustín S., Muñiz Rodríguez, Ana Miriam, Ayerbe García, Rut, Arnedillo-Muñoz, Aurelio, Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Fisioterapia, Cedeño de Jesús, Sindy, Almadana Pacheco, Virginia, Valido-Morales, Agustín S., Muñiz Rodríguez, Ana Miriam, Ayerbe García, Rut, and Arnedillo-Muñoz, Aurelio

Abstract

Background: Patients with chronic respiratory disease have low exercise capacity and limited physical activity (PA), which is associated with worsening dyspnoea, exacerbations, and quality of life. The literature regarding patients with non-cystic fibrosis bronchiectasis (non-CF BQ) is scarce, especially regarding the use of cardiopulmonary exercise tests (CPET) to assess the effects of home-based pulmonary rehabilitation programmes (HPRP). The aim was to evaluate the effect of an HPRP on the exercise capacity of non-CF BQ patients using CPET and PA using an accelerometer. Methods: Our study describes a non-pharmacological clinical trial in non-CF BQ patients at the Virgen Macarena University Hospital (Seville, Spain). The patients were randomised into two groups: a control group (CG), which received general advice on PA and educational measures, and the intervention group (IG), which received a specific 8-week HPRP with two hospital sessions. The variables included were those collected in the CPET, the accelerometer, and others such as a 6 min walking test (6MWT) and dyspnoea. The data were collected at baseline and at an 8-week follow-up. Results: After the intervention, there was a significant increase in peak VO2 in the IG, which was not evidenced in the GC (IG 66.8 ± 15.5 mL/min p = 0.001 vs. CG 62.2 ± 14.14 mL/min, p = 0.30). As well, dyspnoea according to the mMRC (modified Medical Research Council), improved significantly in IG (2.19 ± 0.57 to 1.72 ± 0.05, p = 0.047) vs. CG (2.07 ± 0.7 to 2.13 ± 0.64, p = 0.36). In addition, differences between the groups in walked distance (IG 451.19 ± 67.99 m, p = 0.001 vs. CG 433.13 ± 75.88 m, p = 0.981) and in physical activity (IG 6591 ± 3482 steps, p = 0.007 vs. CG 4824 ± 3113 steps, p = 0.943) were found. Conclusion: Participation in a specific HPRP improves exercise capacity, dyspnoea, walked distance, and PA in non-CF BQ patients.

Published
2022

19. Exercise Capacity and Physical Activity in Non-Cystic Fibrosis Bronchiectasis after a Pulmonary Rehabilitation Home-Based Programme: A Randomised Controlled Trial

Author

Sindy Cedeño de Jesús, Virginia Almadana Pacheco, Agustín Valido Morales, Ana Miriam Muñíz Rodríguez, Rut Ayerbe García, Aurelio Arnedillo-Muñoz, Universidad de Sevilla. Departamento de Medicina, and Universidad de Sevilla. Departamento de Fisioterapia

Subjects
Non-cystic fibrosis bronchiectasis, Exercise Tolerance, Physical activity, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, Fibrosis, Bronchiectasis, Exercise Therapy, non-cystic fibrosis bronchiectasis, pulmonary rehabilitation, exercise capacity, physical activity, cardiopulmonary exercise test, Pulmonary rehabilitation, Dyspnea, Exercise Test, Quality of Life, Exercise capacity, Humans, Exercise, Cardiopulmonary exercise test
Abstract

Background: Patients with chronic respiratory disease have low exercise capacity and limited physical activity (PA), which is associated with worsening dyspnoea, exacerbations, and quality of life. The literature regarding patients with non-cystic fibrosis bronchiectasis (non-CF BQ) is scarce, especially regarding the use of cardiopulmonary exercise tests (CPET) to assess the effects of home-based pulmonary rehabilitation programmes (HPRP). The aim was to evaluate the effect of an HPRP on the exercise capacity of non-CF BQ patients using CPET and PA using an accelerometer. Methods: Our study describes a non-pharmacological clinical trial in non-CF BQ patients at the Virgen Macarena University Hospital (Seville, Spain). The patients were randomised into two groups: a control group (CG), which received general advice on PA and educational measures, and the intervention group (IG), which received a specific 8-week HPRP with two hospital sessions. The variables included were those collected in the CPET, the accelerometer, and others such as a 6 min walking test (6MWT) and dyspnoea. The data were collected at baseline and at an 8-week follow-up. Results: After the intervention, there was a significant increase in peak VO2 in the IG, which was not evidenced in the GC (IG 66.8 ± 15.5 mL/min p = 0.001 vs. CG 62.2 ± 14.14 mL/min, p = 0.30). As well, dyspnoea according to the mMRC (modified Medical Research Council), improved significantly in IG (2.19 ± 0.57 to 1.72 ± 0.05, p = 0.047) vs. CG (2.07 ± 0.7 to 2.13 ± 0.64, p = 0.36). In addition, differences between the groups in walked distance (IG 451.19 ± 67.99 m, p = 0.001 vs. CG 433.13 ± 75.88 m, p = 0.981) and in physical activity (IG 6591 ± 3482 steps, p = 0.007 vs. CG 4824 ± 3113 steps, p = 0.943) were found. Conclusion: Participation in a specific HPRP improves exercise capacity, dyspnoea, walked distance, and PA in non-CF BQ patients.

Published
2022

22. Aspectos claves de la Neumología y la Cirugía Torácica sometidos a debate en la era COVID-19

Author

Jiménez-Ruiz, Carlos A., primary, Valido Morales, Agustin, additional, Perez Chica, Gerardo, additional, Urrutia Landa, Isabel, additional, Rodriguez Portal, Jose Antonio, additional, Arnedillo Muñoz, Aurelio, additional, Cózar Bernal, Fernando, additional, Peces-Barba, Germán, additional, Diego Roza, Carmen, additional, Solano Reina, Segismundo, additional, Rodriguez Suarez, Pedro, additional, Garcia Rio, Francisco, additional, Salas Llinas, Ernest, additional, Garcia Clemente, Marta María, additional, Valencia Gallardo, Jose Manuel, additional, Rodriguez Nieto, María Jesús, additional, Martin de Carpi, Teresa, additional, Sánchez de Cos Escuin, Julio, additional, Estrada Trigueros, Graciliano, additional, Godoy Mayoral, Raúl, additional, Barbeta Sánchez, Enric, additional, Fernández Villar, Alberto, additional, Ros Lucas, Jose Antonio, additional, Martinez Moragón, Eva, additional, and Tomás López, Laura, additional

Published
2021
Full Text
View/download PDF

23. Aspectos claves de la Neumología y la Cirugía Torácica sometidos a debate en la era COVID-19

Author

Jiménez-Ruiz, Carlos A, Valido-Morales, Agustín S., Perez Chica, Gerardo, Urrutia Landa, Isabel, Rodriguez Portal, José Antonio, Arnedillo Muñoz, Aurelio, Cozar Bernal, Fernando, Tomás López, Laura, Universidad de Sevilla. Departamento de Medicina, and Universidad de Sevilla. Departamento de Cirugía

Subjects
Cirugía Torácica, Covid-19, Neumología
Abstract

Para finalizar un año tan complejo como el 2020 a causa de la pandemia por SARS-CoV-2 (COVID-19), tuvimos la oportunidad de celebrar, bajo el amparo de la Sociedad Española de Neumología y Cirugía Torácica (SEPAR), la segunda edición del Foro de presidentes de las sociedades científicas autonómicas de neumología y cirugía torácica de España. Esta pandemia ha puesto en una situación crítica a los sistemas de salud de las diferentes comunidades autónomas españolas, cada uno de ellos con sus peculiaridades y modelos de gestión diferentes. Y en concreto, debido a la afinidad de la COVID-19 por el aparato respiratorio, los servicios de Neumología se han visto directamente involucrados, obligados a modificar sus estructuras y distribución de recursos en tiempo récord para poder proporcionar la mejor asistencia sanitaria posible a estos enfermos. Todo ello, ante una situación de enorme complejidad, no solo por el incremento en la carga asistencial que ha supuesto, sino también por la gran incertidumbre asociada en las fases más iniciales de la pandemia. El desconocimiento de la propia enfermedad y la limitación de recursos disponibles complicó aún más la gestión y la atención sanitaria en una situación sumamente difícil. Estas vivencias relacionadas con la pandemia han marcado esta nueva edición del Foro de presidentes autonómicos y nos ha permitido conocer diferentes puntos de vista y modelos de respuesta según los distintos sistemas de salud implicados, como ya ocurriera en la edición anterior1. No obstante, la vida continúa a pesar de los cambios provocados por el SARS-CoV-2. Por lo tanto, manteniendo el carácter inclusivo e innovador que dio lugar a la creación de este foro a través de la SEPAR, en esta nueva edición se abordaron 5 mesas de debate con temas de especial relevancia para el desarrollo de la Neumología y la Cirugía Torácica en España, cuyas conclusiones se resumen a continuación.

Published
2021

24. Chronic Effects of a Training Program Using a Nasal Inspiratory Restriction Device on Elite Cyclists

Author

Jose Heredia-Jimenez, Aurelio Arnedillo-Muñoz, José Luis González-Montesinos, Carmen Vaz-Pardal, Eva Orantes-Gonzalez, Jose Reina-Novo, Jorge R. Fernandez-Santos, Jesús Gustavo Ponce-González, Ruben Aragon-Martin, [Gonzalez-Montesinos,JL] Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Puerto Real, Cádiz, Spain. [Fernandez-Santos,JR] Galeno Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Cádiz, Spain. [Fernandez-Santos,JR, Aragon-Martin,R, Ponce-Gonzalez,JG] Biomedical Research and Innovation Institute of Cádiz (INiBICA) Research Unit, Puerta del Mar University Hospital University of Cádiz, Cádiz, Spain. [Vaz-Pardal,C] Bahía Sur Andalusian Center for Sports Medicine, Cádiz, Spain. [Aragon-Martin,R, Ponce-Gonzalez,JG] MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Cádiz, Spain. [Arnedillo-Muñoz,A] Allergy and Thoracic Surgery Department, University Hospital Puerta del Mar. Pneumology, Cádiz, Spain. [Reina-Novo,J] National Cycling Coach, IES, Stadium Path , Hong Kong. [Orantes-Gonzalez,E, Heredia-Jimenez,J] Department of Physical Education & Sports, University of Granada, Granada, Spain., Biomedicina, Biotecnología y Salud Pública, and Didáctica de la Educación Física, Plástica y Musical

Subjects
Exercise test, Educación, Health, Toxicology and Mutagenesis, lcsh:Medicine, 0302 clinical medicine, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Respiratory System::Respiratory Function Tests [Medical Subject Headings], Medicine, Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Respiratory Physiological Phenomena::Respiratory Physiological Processes::Respiration [Medical Subject Headings], 030212 general & internal medicine, Respiratory system, Respiratory exchange ratio, Capacidad inspiratoria, Expiratory Time, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings], Respiration, respiratory muscle training, Ciclista, Respiratory Function Tests, Cyclists, Anesthesia, Prueba de esfuerzo, Chemicals and Drugs::Inorganic Chemicals::Carbon Compounds, Inorganic::Carbon Dioxide [Medical Subject Headings], cyclists, Ejercicios respiratorios, Training program, Respiratory rate, Breathing Exercises, Chronic disease, Article, 03 medical and health sciences, Oxygen Consumption, Phenomena and Processes::Metabolic Phenomena::Oxygen Consumption [Medical Subject Headings], Anthropology, Education, Sociology and Social Phenomena::Human Activities::Exercise [Medical Subject Headings], Heart rate, cardiopulmonary exercise testing, Exercise, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Cardiovascular::Heart Function Tests::Exercise Test [Medical Subject Headings], Respiratory muscle training, business.industry, lcsh:R, Enfermedad crónica, Public Health, Environmental and Occupational Health, 030229 sport sciences, Atletas, Carbon Dioxide, Cardiopulmonary exercise testing, Cyclist, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Complementary Therapies::Mind-Body Therapies::Breathing Exercises [Medical Subject Headings], Exercise Test, business, Respiratory minute volume
Abstract

This study compared the response of a 9-week cycling training on ventilatory efficiency under two conditions: (i) Combined with respiratory muscle training (RMT) using a new nasal restriction device (FeelBreathe) (FB group) and (ii) without RMT (Control group). Eighteen healthy elite cyclists were randomly separated into the FB group (n = 10) or Control group (n = 8). Gas exchange was measured breath by breath to measure ventilatory efficiency during an incremental test on a cycloergometer before (Pre) and after (Post) the nine weeks of training. The FB group showed higher peak power (&Delta, (95%HDI) (0.82 W/kg (0.49, 1.17)), VO2max (5.27 mL/kg/min (0.69, 10.83)) and VT1 (29.3 W (1.8, 56.7)) compared to Control at PostFINAL. The FB group showed lower values from Pre to PostPRE in minute ventilation (VE) (&minus, 21.0 L/min (&minus, 29.7, &minus, 11.5)), Breathing frequency (BF) (&minus, 5.1 breaths/min (&minus, 9.4, &minus, 0.9)), carbon dioxide output (VCO2) (&minus, 0.5 L/min (&minus, 0.7, &minus, 0.2)), respiratory equivalents for oxygen (EqO2) (&minus, 0.8 L/min (&minus, 2.4, 0.8)), heart rate (HR) (&minus, 5.9 beats/min (&minus, 9.2, &minus, 2.5)),, respiratory exchange ratio (RER) (&minus, 0.1 (&minus, 0.1, &minus, 0.0) and a higher value in inspiratory time (Tin) (0.05 s (0.00, 0.10)), expiratory time (Tex) (0.11 s (0.05, 0.17)) and end-tidal partial pressure of CO2 (PETCO2) (0.3 mmHg (0.1, 0.6)). In conclusion, RMT using FB seems to be a new and easy alternative ergogenic tool which can be used at the same time as day-to-day training for performance enhancement.

Published
2020

27. Aspectos claves de la Neumología y la Cirugía Torácica sometidos a debate en la era COVID-19

Author

Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Cirugía, Jiménez-Ruiz, Carlos A, Valido-Morales, Agustín S., Perez Chica, Gerardo, Urrutia Landa, Isabel, Rodriguez Portal, José Antonio, Arnedillo Muñoz, Aurelio, Cozar Bernal, Fernando, Tomás López, Laura, Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Cirugía, Jiménez-Ruiz, Carlos A, Valido-Morales, Agustín S., Perez Chica, Gerardo, Urrutia Landa, Isabel, Rodriguez Portal, José Antonio, Arnedillo Muñoz, Aurelio, Cozar Bernal, Fernando, and Tomás López, Laura

Abstract

Para finalizar un año tan complejo como el 2020 a causa de la pandemia por SARS-CoV-2 (COVID-19), tuvimos la oportunidad de celebrar, bajo el amparo de la Sociedad Española de Neumología y Cirugía Torácica (SEPAR), la segunda edición del Foro de presidentes de las sociedades científicas autonómicas de neumología y cirugía torácica de España. Esta pandemia ha puesto en una situación crítica a los sistemas de salud de las diferentes comunidades autónomas españolas, cada uno de ellos con sus peculiaridades y modelos de gestión diferentes. Y en concreto, debido a la afinidad de la COVID-19 por el aparato respiratorio, los servicios de Neumología se han visto directamente involucrados, obligados a modificar sus estructuras y distribución de recursos en tiempo récord para poder proporcionar la mejor asistencia sanitaria posible a estos enfermos. Todo ello, ante una situación de enorme complejidad, no solo por el incremento en la carga asistencial que ha supuesto, sino también por la gran incertidumbre asociada en las fases más iniciales de la pandemia. El desconocimiento de la propia enfermedad y la limitación de recursos disponibles complicó aún más la gestión y la atención sanitaria en una situación sumamente difícil. Estas vivencias relacionadas con la pandemia han marcado esta nueva edición del Foro de presidentes autonómicos y nos ha permitido conocer diferentes puntos de vista y modelos de respuesta según los distintos sistemas de salud implicados, como ya ocurriera en la edición anterior1. No obstante, la vida continúa a pesar de los cambios provocados por el SARS-CoV-2. Por lo tanto, manteniendo el carácter inclusivo e innovador que dio lugar a la creación de este foro a través de la SEPAR, en esta nueva edición se abordaron 5 mesas de debate con temas de especial relevancia para el desarrollo de la Neumología y la Cirugía Torácica en España, cuyas conclusiones se resumen a continuación.

Published
2021

28. Anxiety, Depression, and Asthma Control: Changes After Standardized Treatment

Author

L. Fernandez Pellon, E. Macias Fernandez, Manuel J Rial, E. Morchon Miguel, V. Vilella Tomás, P. Marin Martinez, V. De Luque Piñana, V. García Paz, M. Morales Villarejo, J. Ruiz Hornillos, J. Herrero Jarque, J. Florido Lopez, J. Beitia Mazuecos, M. Rojas Vilchez, J. Medina Gallardo, J. Valldeperas Combas, A. Pallarés Sanmartín, I. García Núñez, J. Castro Landin, R. Diaz Campos, G. Gala Ortiz, M. Mena Rodriguez, O. Villarreal Balza De Vallejo, Vicente Plaza, E. Pinto Nogues, A. Suárez Rodríguez, P. Sánchez López, S. Díaz Angulo, F. Sola Martinez, M. Moscardó Orenes, M. Alvariño Martin, R. Tejedor Romera, J. Orta Cuevas, Z. Vasquez Gambasica, B. García Figueroa, A. Letran Camacho, M. Modesto Alapont, M. Cervera Del Pino, P. Benito Martinez, S. Varela Losada, F. Carballada Gonzalez, Irina Bobolea, M. Díaz Palacios, Y. Anta Mejias, D. González De Olano, J. Martos Velasco, P. Prieto Montaño, A. Sanchez Alonso, M. Martínez Ceres, J. Donado Uña, Ò. Sotorra Elias, B. Alcázar Navarrete, A. Arnedillo Muñoz, J. Alcazar Ramirez, J. Jiménez López, M. Alvarez Puebla, M. Antón Girones, J. Compaired Villa, P. Mata Calderon, M. Escribano Rodriguez, C. Morales García, I. Molero Sancho, M. De Las Marinas Alvarez, T. Bazus Gonzalez, M. Soria Esojo, A. Vega Castro, A. Moreno Fernandez, G. Jorro Martínez, E. Ortega Sáenz De Tejada, A. Regueiro Moreira, M. Garcimartin Galicia, A. Alonso Gomez, R. Rodriguez Martinez, J. Liñana Santafé, I. Ansotegui Zubeldia, R. Lama Martinez, A. Saura Vinuesa, N. Segura Arazuri, M. Torrecillas Toro, M. Climent Gregori, M. Herrerias Peña, T. Peña Miguel, C. Vila Albelda, C. Diaz Donado, M. Hernandez, A. Losada Peña, M. Gandolfo Cano, J. Montoro Lacomba, J. Quiralte Enriquez, R. Rodríguez Pacheco, M. Arroyo Cozar, P. Rubinstein Aguñin, M. Blanco Aparicio, F. Alvarez Gutierrez, C. Merinas Lopez, R. Mayorgas Costoya, M. Franco Campos, J. Garcia De Pedro, V. Moreno Garcia, J. De Frutos Arribas, J. Alvarez Fernandez, A. Robles Iniesta, M. Do Muíño Joga, A. Bueso Fernandez, P. Serrano Dominguez, M. Jimenez Lara, P. Losada Llorente, C. Colás Sanz, I. Raducan, B. Requejo Mañana, M. Mota Godoy, M. Martos Calahorro, F. Ortiz Portal, J. Zapata Yébenes, F. Nicolau Pastrie, C. Rabade Castedo, M. Salvador Segarra, F. Callejas González, M. Chacon Patiño, G. González Álvarez, J. Olaguibel Rivera, P. Gonzalez Delgado, B. Orosa Bertol, E. De Santiago Delgado, J. Cumplido Bonny, R. Nuñez Orjales, Antonio Fernandez-Sanchez, B. Añíbarro Bausela, D. Ferrer Pargada, S. Niño Bernal, A. Cobas Paz, B. Huertas Barbudo, J. Ciruelos Ayuso, M. Lara Jiménez, D. Gutierrez Fernandez, G. Castaño De Las Pozas, Y. García Villamuza, F. Sánchez-Toril López, E. Naval Sendra, C. Andreu Balaguer, M. Rico Diaz, L. Navarro Seisdedos, D. El-Qutob López, J. Ruiz Cubillan, Miguel Ibáñez Rodríguez, L. Fontan Garcia-Boente, M. Rivera Ortun, A. Padilla Galo, M. Muñoz Pamplona, I. Perez Sampedro, F. Garcia Gonzalez, E. Gómez Nieves, S. Aparicio Español, Astrid Crespo, A. Lloris Bayo, R. Lleonart Bellfill, E. Burches Baixauli, R. Andujar Espinosa, I. Picans, F. Linde De Luna, A. Tabar Purroy, L. Valverde Vazquez, R. Blanco Gonzalez, M. Ballester Canelles, P. Barranco Sanz, F. Ruano Perez, A. Romero Ortiz, S. Jimenez Timon, G. De Luiz Martínez, C. Baeza Martinez, G. Bernaola Hortigüela, J. Chamorro Mohedad, M. Garcés Sotillos, R. Moreno Borque, M. Moro, I. Ali García, S. Lizarza Mendizabal, J. Almagro Lopez, C. Perez Carral, J. Cegoñino De Sus, M. Reche Frutos, R. González Perez, M. Domínguez Fuentes, L. Cassini Gomez De Cadiz, A. Feliu Vila, M. Dordal Culla, M. Corbacho Abelaira, Y. Puente Crespo, D. Romero Ribate, J. Rozadilla Sacanell, J. Lopez Caballero, A. Velez Ruiz De Lobera, A. Montoro De Francisco, M. Ramirez Prieto, N. Marina Malanda, J. Juanola Pla, M. Millan Gonzalez, N. Subira Farre, P. Cordero Rodriguez, F. Gonzalez Barcala, S. Herrera Lara, M. Peña Arellano, J. Igea Aznar, R. Alvarez Sintes, E. Martinez Moragon, J. Greses Giner, M. Martínez Riaza, G. Mediero Carrasco, P. Catalán Serra, M. Rodriguez Hernandez, S. Porcel Carreño, Joaquín Sastre, A. Ruiz San Francisco, R. Bernabeu Mora, M. Alwakil Olbah, H. Izaguirre Flores, J. Subiza Garrido-Lestache, B. Labeguerie Arenaza, B. Presedo Garazo, S. Cimbollek, A. Fuster Gomila, G. Minguez Martin, M. Martín Pérez, S. Garrido Fernández, F. Iglesias Rio, A. Veres Racamonde, B. Rodriguez Jimenez, F. Muñoz Bellido, A. Moral De Gregorio, A. López Viña, J. Marin Torrado, I. Flores Martín, M. Avilés Inglés, A. Lahuerta Castro, and P. Galindo Bonilla

Subjects
Adult, Male, Spirometry, medicine.medical_specialty, Vital capacity, Anxiety, Hospital Anxiety and Depression Scale, Severity of Illness Index, 03 medical and health sciences, FEV1/FVC ratio, 0302 clinical medicine, Forced Expiratory Volume, Internal medicine, Health care, Humans, Immunology and Allergy, Medicine, 030212 general & internal medicine, Depression (differential diagnoses), Asthma, medicine.diagnostic_test, Depression, business.industry, Middle Aged, medicine.disease, respiratory tract diseases, 030228 respiratory system, Female, medicine.symptom, business
Abstract

Background It has been documented that anxiety and depression are prevalent in patients with asthma and are associated with greater frequency of exacerbations, increased use of health care resources, and poor asthma control. Objective To examine the association of asthma diagnosis with symptoms of depression/anxiety and asthma control not only at baseline but also over a 6-month period of specialist supervision. Methods We enrolled 3182 patients with moderate to severe asthma. All were evaluated with spirometry, the Asthma Control Test, and the Hospital Anxiety and Depression Scale at baseline and at 6 months. Treatments were decided by specialists according to published guidelines. Results At baseline, 24.2% and 12% of the patients were diagnosed with anxiety and depression, respectively, according to the Hospital Anxiety and Depression Scale. After 6 months, anxiety and depression improved, affecting 15.3% and 8.1% of patients, respectively (P Conclusion Under standardized asthma care and after a specific visit with the specialist, patients present significant improvement in these psychological disorders and exhibit better asthma control and functional parameters.

Published
2018
Full Text
View/download PDF

35. Role of comorbidities in stable COPD patients mortality

Author

José Luis López-Campos, Inmaculada Alfageme Michavilla, Aurelio Arnedillo Muñoz, Francisco Casas Maldonado, and Pilar Cordero Montero

Subjects
Mechanical ventilation, medicine.medical_specialty, COPD, business.industry, medicine.medical_treatment, Hospital Anxiety and Depression Scale, medicine.disease, Comorbidity, Internal medicine, Heart failure, medicine, Myocardial infarction, Intensive care medicine, business, Depression (differential diagnoses), Cause of death
Abstract

Objective: to assess the role of comorbidities with all cause mortality in patients with stable COPD Material and Methods: prospective, multicenter, longitudinal study of patients with stable COPD. We recorded demographic characteristics, respiratory functional tests, medication received, comorbidities, Charlson comorbidity index and hospital anxiety and depression scale. Patients were followed up for 3 years. In case of death it was investigated to determine the real cause of death Results: 138 patients were studied with a mean age of 66.3±10.3 years and mean FEV1 of 51.3±16.9%. The mean Charlson index was 4.66 ± 1.57. 17.2% had depression and 12.7% anxiety. Thirteen (9.5%) patients died, 5 of lung cancer, 5 COPD exacerbation, 1 colon cancer, another for acute myocardial infarction (AMI) and another one for congestive heart failure (CHF). The bivariate analysis showed statistical differences in Charlson index, number of comorbidities, hypertension, AMI, CHF, treatment with noninvasive mechanical ventilation, antidepressants and anxiolytics. In the multivariate analysis the number of comorbidities (HR 1.926; 95%IC: 1.384-2.680) and anxiolytic treatment (HR 4.072; IC95%: 1.106-14.987) showed relationship with mortality. Kaplan-Meier survival plots showed that patients with 2 o more comorbilities, in addition to COPD, have higher mortality than patients with 1 or no comorbidity (35.52±0.2 vs 33±1.3 months, p=0,039). Conclusions: The prevalence of comorbidities in patients with stable COPD was high. Mortality in these patients is related to the number of comorbidities and anxiolytic treatment. Mortality was higher in patients with 2 o more comorbidities. Funded by NEUMOSUR.

Published
2016
Full Text
View/download PDF

36. Efectos del entrenamiento de la musculatura respiratoria sobre el rendimiento. Revisión bibliográfica

Author

J.L. Costa Sepúlveda, A. Arnedillo Muñoz, J. Fernández Santos, José Luis González-Montesinos, R. Gómez Espinosa de los Monteros, and C. Vaz Pardal

Subjects
Rendimiento, Performance, Physiology (medical), Músculos respiratorios, Entrenamiento, Respiratory muscles, Training, Orthopedics and Sports Medicine
Abstract

ResumenActualmente, es aceptado por la comunidad científica que el sistema respiratorio puede limitar el ejercicio en personas con enfermedad pulmonar y/o cardiovascular. El objetivo del presente artículo es la revisión de algunos estudios realizados en relación al papel limitante del sistema respiratorio en el rendimiento físico de deportistas. Se realiza una breve descripción técnica de los dispositivos más utilizados para el entrenamiento de la musculatura respiratoria. Finalmente, se presentan los resultados más representativos, obtenidos por diversos investigadores y en distintas poblaciones, relacionados con el entrenamiento de la musculatura respiratoria y sus efectos en el rendimiento físico.Los resultados obtenidos en las distintas investigaciones consultadas sobre el entrenamiento de los músculos respiratorios son dispares, puesto que algunos han mostrado mejoras significativas, mientras otros no han mostrado grandes efectos en el rendimiento. En todos ellos se refleja cómo el sistema respiratorio es un factor limitante del rendimiento físico en deportistas y es preciso plantearse nuevas metodologías, protocolos y planificaciones en el entrenamiento deportivo.El entrenamiento de los músculos respiratorios, tanto mediante dispositivos umbral, de resistencia, o isocapnica, puede provocar mejoras en valores como la presión inspiratoria máxima y mejoras en el rendimiento de algunos deportes; sin embargo, son muy escasos los estudios que han encontrado mejoras en el consumo máximo de oxígeno (VO2max).Las discrepancias entre los estudios analizados pueden estar provocadas por diferencias en las intensidades y duración de los ejercicios utilizados, así como por diferencias en el diseño experimental y el nivel de condición física de los sujetos.AbstractIt is currently accepted by the scientific community that the respiratory system may limit the exercise in people with lung disease and / or cardiovascular disease. The aim of this study is to review some studies about the limiting role of the respiratory system in the physical performance of athletes and the breath factors that can limit it. We make a brief technical description of the devices used for respiratory muscle training. Finally, we present the most representative results obtained by different researchers in different populations, related to respiratory muscle training and its effects on physical performance.Results obtained in different studies about respiratory muscles training are uneven as some have shown significant improvements, while others have shown no major effects on the performance. All of them reflect that respiratory system is a limiting factor in the physical performance of athletes and it is necessary to consider new methodologies, protocols and plans in sports training.Respiratory muscles training, either by a threshold device, resistance, or isocapnic, may cause improvements in the values of maximum inspiratory pressure and improvements in some sports performance, however, very few studies have found improvements in peak oxygen consumption.Disagreements between the analyzed studies may be caused due to differences in intensity and duration of the exercises used in the tests, as well as by differences between the experimental design and the physical fitness level of subjects.

Published
2012
Full Text
View/download PDF

37. Actinomicosis torácica: una entidad de difícil diagnóstico

Author

J.E. González-Moya, A. Arnedillo-Muñoz, L. García-Agudo, P. Martín-Peral, A. León-Jiménez, and P. García-Martos

Subjects
business.industry, Medicine, General Medicine, business, Humanities
Abstract

La actinomicosis es una infeccion bacteriana, poco frecuente, producida por microorganismos del genero Actinomyces, siendo Actinomyces israelii (A. israelii) el mas habitual, aunque otros microorganismos pueden dar lugar a cuadros indistinguibles e incluso formar conglomerados que se asemejan a los granulos de azufre de Actinomyces1. Se trata de bacilos grampositivos, filamentosos, ramificados, no esporulados, anaerobios o microaerofilos, de crecimiento lento, colonizadores habituales de la boca, colon y vagina. Su cultivo requiere medios enriquecidos, donde tardan de 3 a 10 dias en crecer, aunque puede prolongarse hasta 24 semanas2. La mayor rentabilidad diagnostica se obtiene con el pus, aunque solo un 26% de los cultivos resultan positivos1. Con frecuencia la infeccion es polimicrobiana, considerandose como copatogenos frecuentes a algunos bacilos gramnegativos, como Fusobacterium, Eikenella, Bacteroides y Enterobacterias, asi como a Staphylococcus y Streptococcus. Del 15 al 45% de los casos se localizan en el torax, a menudo como resultado de la aspiracion de material infeccioso de la orofaringe con menos frecuencia se debe a una perforacion esofagica con extension al mediastino, o se propaga desde un foco abdominal o por via hematogena3. La infeccion suele extenderse a la pleura

Published
2012
Full Text
View/download PDF

39. El porqué de la GesEPOC en nuestro entorno

Author

Aurelio Arnedillo Muñoz

Subjects
Pulmonary and Respiratory Medicine, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, business.industry, Medicine, 030212 general & internal medicine, business, Humanities
Published
2017
Full Text
View/download PDF

40. Impacto de las agudizaciones e ingresos en la EPOC

Author

Aurelio Arnedillo Muñoz

Subjects
Pulmonary and Respiratory Medicine, Gerontology, COPD, medicine.medical_specialty, business.industry, Pulmonary disease, After discharge, medicine.disease, Pulmonary function testing, Natural history, Quality of life, Hospital admission, medicine, In patient, Intensive care medicine, business
Abstract

During the natural history of patients with chronic obstructive pulmonary disease (COPD), an increase in symptom severity can occur, called exacerbated COPD (ECOPD), sometimes requiring hospital admission. Although there is ongoing debate on the definition of ECOPD –leading to a lack of homogeneity in the numerous studies performed– exacerbations negatively affect patients, producing clinical and pulmonary function deterioration in the long term. Exacerbations also decrease quality of life in the medium- and long-term and have a high social and health cost, especially during hospital admission. Finally, ECOPD increases mortality in patients in the short-term, during hospital admission, and after discharge. In view of all of the above, prevention of ECOPD has become one of the main objectives in these patients.

Published
2010
Full Text
View/download PDF

41. Revista del año de la EPOC

Author

Aurelio Arnedillo Muñoz, José Luis López-Campos, and Elena Miguel Campos

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, COPD, Rehabilitation, business.industry, medicine.medical_treatment, MEDLINE, medicine.disease, Short stay, Medical advice, medicine, Physical therapy, Respiratory muscle, Anxiety, Sputum, medicine.symptom, Intensive care medicine, business
Abstract

There have been significant advances in the knowledge in the thoracic and extrathoracic aspects of chronic obstructive pulmonary disease (COPD) in the past few years. COPD is associated with numerous comorbidities, the prevalences of which have recently been evaluated. Dyspnea has been shown to be associated with neuropsychiatric disturbances, such as anxiety. Muscular dysfunction has been associated with inflammation and oxidative stress, in which respiratory muscle satellite cells play an important role in repair. Respiratory rehabilitation and physiotherapy must form an important part of individualised patient treatment analogous to the pharmacological treatment. As regards acute exacerbations, infection is the cause of 75% of them, sputum characteristics and the suspicion of Pseudomonad being key factors in the antibiotic treatment. Questions, such as markers which can detect the origin of the infection, prognostic factors, or the role of short stay pneumology units, are of particular importance. The variability in COPD treatments and the lack of suitable international clinical guidelines, continue to be subjects of debate. To the poor use of the treatment schemes in the guidelines, can be added the irregular uses of inhaled medication, the insufficient use of medical advice or the low intervention in cigarette smoking in all age groups.

Published
2009
Full Text
View/download PDF

42. Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone

Author

Stempel, Da, Raphiou, Ih, Kral, Km, Yeakey, Am, Emmett, Ah, Prazma, Cm, Buaron, Ks, Pascoe, Sj, Austri, Investigators, Altieri, Hh, Antuni, Jd, Bergna, Ma, Cuadrado, Ja, De Gennaro MS, Fazio Lizandrelo CL, Gattolin, G, Gosn, Am, Larrateguy, Ld, Marcipar, Am, Maspero, Jf, Medina, Iv, Perez Chada RD, Silva, D, Victorio, Cf, Bardin, Pg, Carroll, Pa, Clements, Bs, Dore, Nd, Robinson, Pd, Fitzgerald, Da, Robinson, Pj, Russo, Ma, Sajkov, D, Thomas, Ps, Upham, Jw, Forstner, B, Kaik, G, Koeberl, Gh, Studnicka, M, Wallner, G, Balthazar, Y, Bauler, A, Dupont, Lj, Martinot, Jb, Ninane, V, Peché, R, Pilette, C, Dimitrova, R, Dimova, D, Kissyova Ibrishimova, G, Loboshka Becheva, M, Machkovska, M, Madjarov, S, Mandazhieva Pepelanova, M, Naidenova, I, Noleva, K, Takovska, N, Terziev, C, Aggarwal, Nk, Chapman, Kr, Csanadi, Ma, Dhillon, R, Henein, S, Kelly, Aj, Lam, As, Liem, Jj, Lougheed, Md, Lowe, Dw, Rizvi, Q, van den Berg, L, Zidel, B, Barros Monge MJ, Calvo Gil MA, Castillo Hofer CR, Diaz Amor PV, Lezana Soya, V, Quilodran Silva CN, Bolivar Grimaldos, F, Solarte-Rodriguez, I, Butkovic-Tomljanovic, R, Hegedus-Jungvirth, M, Ivkovic-Jurekovic, I, Simunov-Karuza, G, Buresova, M, Bursova, J, Fratrik, J, Guttlerova, E, Hartman, P, Jirmanova, I, Kalina, P, Kolman, P, Kucera, M, Povysilova, L, Pravda, P, Svabkova, A, Zakova, L, Backer, V, Maltbaek, N, Johnsen, Cr, Aries, Sp, Babyesiza, A, Barth, D, Benedix, A, Berg, P, Bergtholdt, B, Bettig, U, Bindig, Hw, Botzen, U, Brehler, R, Breyer, Go, Bruckhaus-Walter, M, Dapper, T, Eckhard, Jg, Engelhard, R, Feldmeyer, F, Fissan, H, Franz, Kh, Frick, Bs, Funck, J, Gessner, Cm, Ginko, T, Grigat, Ce, Grimm-Sachs, V, Groth, G, Hampf, J, Hanf, G, Havasi-Jost, G, Heinz, Gu, Helm, K, Hoeltz, S, Hofmann, S, Jander, R, Jandl, M, Jasch-Hoppe, B, Jung, T, Junggeburth, Jj, Kardos, P, Knueppel, W, Koch, T, Kolorz, C, Korduan, M, Korth-Wiemann, B, Krezdorn, Hg, Kroker, A, Kruell, M, Kuehne, P, Lenk, U, Liefring, E, Merke, J, Micke, L, Mitlehner, W, Mueller, H, Naudts, If, Neumann, G, Oldenburg, W, Overlack, A, Panzer, F, Reinholz, N, Remppis, R, Riegel, P, Rueckert, P, Schaetzl, Rj, Schauer, U, Hamelmann, E, Schenkenberger, I, Schlegel, V, Scholz, G, Schroers, M, Schwittay, A, Sebert, M, Tyler, K, Soemantri, Pa, Stock, P, Stuchlik, G, Unland, M, von Mallinckrodt, C, Wachter, J, Weber, U, Weberling, F, Wehgartner-Winkler, S, Weimer, J, Wiemer, S, Winkelmann, Ej, Zeisler, Kh, Ziegner, A, Zimny, Hh, Andrasofszky, Z, Bartha, A, Farkas, M, Gömöri, K, Kis, S, Major, K, Mészáros, I, Mezei, M, Rakvacs, M, Szalai, Z, Szántó, J, Szentesi, M, Szolnoki, E, Valyon, E, Zibotics, H, Anwar, J, Arimah, C, Djajalaksana, S, Rai, Ib, Setijadi, Ar, Setyanto, Db, Susanti, F, Syafiuddin, T, Syamsi, Ln, Wijanarko, P, Yunus, F, Bonavia, M, Braga, M, Chetta, Aa, Cerveri, I, Luisetti, M, Crimi, N, Cutrera, R, De Rosa, M, Esposito, S, Foresi, A, Gammeri, E, Iemoli, E, Legnani, Dl, Michetti, G, Pastorello, Ea, Pesci, A, Pistolesi, M, Riva, E, Romano, A, Scichilone, N, Terracciano, L, Tripodi, S, Choi, I, Kim, C, Kim, Js, Kim, Wj, Koh, Yy, Kwon, Ss, Lee, Sh, Lee, S, Lee, Sk, Park, Cs, Cirule, I, Eglite, R, Petrova, I, Poga, M, Smiltena, I, Chomiciene, A, Davoliene, I, Griskeviciene, V, Naudziunas, A, Naudziunas, S, Rudzeviciene, O, Sitkauskiene, B, Urbonas, G, Vaicius, D, Valavicius, A, Valiulis, A, Vebriene, J, bin Abdul Aziz FA, Daud, M, Ismail, Ai, Tengku Saifudin TI, Md Kassim RM, Mohd Fadzli FB, Wan Mohamad WH, Aguilar Dominguez PE, Aguilar-Orozco, Ra, Garza-Salinas, S, Ramirez-Diaz, Sp, Sánchez Llamas, F, Soto-Ramos, M, Velarde-Mora, Hj, Aguirre Sosa, I, Cisneros, Am, Estrella Viladegut RA, Matsuno Fuchigami, A, Adiaz-Baui, Tt, Bernan, Ap, Onia, Af, Sandagon, Mj, S-Naval, S, Yu, Cy, Bartuzi, Z, Bielous-Wilk, A, Błażowski, Ł, Bożek, A, Brzostek, J, Chorostowska-Wynimko, J, Ciekalska, K, Ziora, D, Cieslicki, J, Emeryk, A, Folcik, K, Gałuszka-Bilińska, A, Gawlik, R, Giejlo, M, Harat, R, Hofman, T, Jahnz-Różyk, K, Jedrzejczak, M, Kachel, T, Kamiński, D, Kelm Warchol, A, Konieczny, Z, Kwasniewski, A, Leszczyński, W, Mincewicz, G, Niezgoda, K, Olszewska-Ziąber, A, Onasz-Manitius, M, Pawlukiewicz, M, Piotrowicz, P, Piotrowski, W, Pisarczyk-Bogacka, E, Piskorz, P, Prokop-Staszecka, A, Roslan, A, Słomka, A, Smalera, E, Stelmach, I, Swierczynska-Krepa, M, Szmidt, M, Tarnowska-Matusiak, M, Tłuczykont, B, Tyminska, K, Waszkuc-Golonko, J, Wojciechowska, I, Alexandrescu, Ds, Neamtu, Ml, Todea, D, Alekseeva, E, Aleksandrova, E, Asherova, I, Barbarash, Ol, Bugrova, O, Bukreeva, Eb, Chermenskiy, A, Chizhova, O, Demko, I, Evdokimova, A, Giorgadze, Ml, Grigoryev, S, Irkhina, I, Khurkhurova, Nv, Kondyurina, Eg, Kostin, Vi, Kudelya, L, Laleko, Sl, Lenskaya, L, Levashov, S, Logvinenko, N, Martynov, A, Mizernitski, Y, Nemtsov, B, Novozhenov, Vg, Pavlishchuk, S, Popova, Vv, Reshetko, Ov, Sherenkov, A, Shirinsky, Vs, Shpagina, L, Soloviev, Ki, Tkachev, A, Trofimov, Vi, Vertkin, Al, Vorobeva, E, Idrisova, E, Yakushin, S, Zadionchenko, V, Zhiglinskaya, O, Zykov, K, Dopudja Pantic, V, Nadaskic, R, Nestorovic, B, Skodric Trifunovic, V, Stojanovic, A, Vukcevic, M, Vujic, T, Mitic Milikic, M, Banovcin, P, Horvathova, H, Karako, P Sr, Plutinsky, J, Pribulova, E, Szarazova, M, Zlatos, A, Adams, L, Badat, A, Bassa, A, Breedt, J, Bruning, A, Ellis, Gc, Emanuel, S, Fouche, Lf, Fulat, Ma, Gani, M, Ismail, Ms, Jurgens, Jc, Nell, H, Nieuwoudt, G, Noor, F, Bolliger, Ct, Puterman, As, Siddique, N, Trokis, Js, Vahed, Ya, Van Der Berg BJ, Van der Linden, M, Van Zyl, L, Visser, Ss, Antépara Ercoreca, I, Arnedillo Muñoz, A, Barbe Illa, F, Barreiro López, B, Blanco Aparicio, M, Boada Valmaseda, A, Bosque García, M, Bustamante Ruiz, A, Carretero Anibarro, P, Del Campo Matias, F, Echave-Sustaet, Jm, Espinosa de los Monteros Garde MJ, Garcia Hernandez GM, López Viña, A, Lores Obradors, L, Luengo Planas MT, Monsó Molas, E, Navarro Dourdil, A, Nieto García AJ, Perpina Tordera, M, Picado Valles, C, Rodriguez Alvarez Mdel, M, Saura Vinuesa, A, Serra Batlles, J, Soler Sempere MJ, Toran Montserrat, P, Valdés Cuadrado LG, Villasante Fernandez-Montes, C, Cheng, Sl, Chern, Jh, Chiu, Mh, Chung, Cl, Lai, Rs, Lin, Ck, Liu, Yc, Wang, Cc, Wei, Yf, Amer, L, Berenfus, Vi, Besh, L, Duka, Kd, Fushtey, Im, Garmash, N, Dudnyk, O, Godlevska, O, Vlasenko, Ma, Hospodarskyy, I, Iashyna, L, Kaladze, M, Khvelos, Si, Kostromina, Vp, Krakhmalova, O, Kryuchko, T, Kulynych, Ov, Krasko, Mp, Levchenko, O, Litvinova, T, Panina, Ss, Pasiyeshvili, Lm, Prystupa, Ln, Romaniuk, Li, Sirenko, I, Synenko, Vi, Vynnychenko, Lb, Yatsyshyn, Ri, Zaitsev, I, Zhebel, V, Zubarenko, O, Arthur, Cp, Brown, V, Burhan, H, Chaudhuri, R, Collier, D, Barnes, Nc, Davies, Ej, Ellery, A, Kwok, S, Lenney, W, Nordstrom, M, Pandya, Hc, Parker, Iw, Rajakulasingam, K, Seddon, P, Sharma, R, Thomas, Ec, Wakeling, Ja, Abalos-Galito, M, Abboy, C, Abreu, E, Ackerman, If, Acosta, Ia, Adaoag, Aa, Ahmed, M, Ali, Mi, Allen, Dr, Allen GG Jr, Diogo, Jj, Allison, Dc, Alwine, Lk, Apaliski, Sj, Arastu, Rs, Arora, Cm, Auerbach, D, Azzam, Sj, Badar FL 3rd, Baker, Jw, Barasch, Jp, Barber, Ma, Bardinas-Rodriguez, R, Barreiro, Tj, Baumbach, Rr, Baur, Ce, Baxter, Bs, Beach, Jl, Beasley, Rl, Beavins, Je, Beliveau, Wj, Benbow, Mj, Bennett, Nl, Bennett, Rl, Bernal, H, Bernstein, Di, Blaiss, Ms, Blumenthal, Kw, Boas, Sr, Borders, Jl, Boscia, Ja, Boulware, Wn, Bowling, Bt, Brabec, Ba, Bramlet, Dg, Figueroa, Dp, Brautigam, Df, Brownell, Jm, Bruce, Tr, Call, Rs, Campbell, Ca, Canaan, Ya, Cannon, Df, Carpio, Jm, Cathcart, Ws, Cevallos, Jp, Chauhan, Av, Chuang, Rb, Chevalier, D, Christensen, J, Christensen, Ta, Christina, Mo, Chrzanowski, Rr, Civitarese, Fa, Clark, Jp, Clifford, Dp, Lapidus, Rj, Coggi, Ja, Lenz, Jj, Cohen, Kr, Collins, Bg, Collins, H, Comellas, A, Condit, J, Cordasco EM Jr, Corder, Cn, Covar, Ra, Coverston, Kd, Croce, Sa, Cruz, H, Curtis, Ct, Daftary, Pk, Dalan, D, Dalawari, Sp, Daly, Wc, Davis, Kc, Dawes, Kw, Decotiis, Ba, Deluca, Rf, Desantis, Dm, De Valle OL, Diaz, Jl, Diaz, Jd, Dice, Jp, Elizalde, A, Hosler, Mr, Dixon, C, Dobkin, La, Dobrusin, Rs, Dransfield, Mt, Ebbeling, Wl, Edwards, Jd, Elacion, Jm, Elkayam, D, Ellison, Wt, Elsen, Jr, Engel, Lr, Ensz, Dj, Ericksen, Cl, Ervin, Je, Fang, C, Abrahamian, F, Farrah, Vb, Field, Jd, Fishman, Hj, Florea, R, Nayyar, S, Focil, A, Focauld, F, Franco MA Jr, Frandsen, Br, Ganti, K, Garcia, Fl, Lee, Wm, Garscadden, Ag, Gatti, Ea, Gellady, Am, George, Ar, Gibbon, Gw, Gleason, Gp, Goldberg, P, Goldstein, Mf, Gonzalez, Ge, Gower, Rg, Grande, Ja, Gregory, D, Grubb, Sd, Guthrie, Rp, Haas, Ta, Haft, Ks, Hajal, R, Hammond, Gd, Hansel, Nn, Hansen, Vr, Harris, Af, Hartman, An, Harvey, Rr, Hazan-Steinberg, S, Headley, Dm, Heigerick, Gc, Heller, Bn, Hendrix, El, Herrod, Jn, Hewitt, Mj, Hines, Rl, Hirdt, Ap, Hirschfield, Ja, Hoffman, Ks, Hogan, Ad, Howland, Wc, Hsu, Cc, Hsu, Fj, Hubbard, Wm, Hudson, Jd, Huffman, C, Hussain, M, Ioachimescu, Oc, Ismail, Ym, Jaffrani, Na, Jiang, N, Jones, Sw, Jordan, Rs, Joshi, Ke, Kaashmiri, Mw, Kalafer, M, Kamdar, Ba, Kanuga, Jg, Kao, Nl, Karetzky, M, Katsetos, Jc, Kay, Js, Kimmel, Ma, Kimura, Sh, Kingsley, Jk, Mahmood, Sm, Subich, Dc, Kirstein, Jl, Kleerup, Ec, Klein, Rm, Koh, Dw, Kohli, N, Koura, Fa, Kovacs, Sp, Kratzer, J, Kreit, Ci, Kreutter, Fm, Kubicki, Tm, Labuda, Jm, Latorre, Aj, Lara, Mm, Lechin, Ae, Lee, Jj, Lee, Md, Lentnek, Al, Lesh, Kw, Levins, Pf, Anspach, Rb, Levinsky, Dm, Lillestol, Mj, Lim, H, Livezey, Md, Lloyd-Turney, Cw, Lockey, Rf, Long, Ra, Lynch, Mj, Macgillivray, Bk, Mahadevan, Kp, Makam, Sk, Maloney, Mj, Mapel, D, Margolis, Bd, Margulies, J, Martin, Ef, Martin, Ee, Mascolo, M, Mataria, H, Sunbuli, M, Mathur, Rn, Mattar, Pn, Maynard, Km, Maynard, N, Mccormick, B, Mcelya, M, Mcevoy, Ce, Mckenzie, Wc, Medwedeff, Le, Mehta, Kd, Melamed, Ir, Meli, Jv, Merrick, Bh, Meyers, Pj, Miller, Bt, Minton, Sm, Miranda, Fg, Mohar, De, Montenegro, Ch, Morris, Fa, Morrison, Bs, Moss, Mh, Munoz, F, Naini, Gr, Nakamura, Ct, Naseeruddin, S, Nassim, C, Navazo, Lj, Nissim, Je, Norman, D, Oberoi, Ms, O'Connor, Tm, Offenberger, J, Orr, Rr, Osea, Ea, Paine, Wj, Rasmussen, Nl, Palatnik, M, Pangtay, D, Panuto, Ja, Patel, M, Perera, Ms, Perez, A, Peters PH Jr, Pimentel SM Jr, Pluto, Tm, Pollock, Mt, Posner, Ls, Pritchard, Jc, Pudi, Kk, Puig, Cm, Qaqundah, Py, Radbill, Mk, Rahman, St, Raikhel, M, Raissy, Hh, Ramstad, Ds, Ranasinghe, Es, Rangel, Os, Rapo, Se, Raschal, Sp, Reddy, Dg, Rehman, Sm, Reyes, Sr, Rhodes, Rb, Riffer, E, Rihal, Ps, Riley ED 4th, Rodriguez, Dh, Rogers, Cm, Rohlf, Jl, Romeu, H, Roney, Cw, Ronsick, So, Rosen, Jb, Rowe, Ms, Ruoff, Ge, Ryan, Eh, Saff, Rh, Saini, N, Anand, S, Balakrishnan, K, Samuels, Bs, Samuelson, Rj, Saniuk, Rj, Sargeant, Wo, Saunders, Mk, Saway, W, Scarupa, Md, White, Mv, Schear, Mj, Schwarz, Cm, Scott, Rb, Segall, N, Seibert, Af, Seidmeyer, V, Seidner, Mr, Seifer, Fd, Serje, J, Shah, Ms, Shah, Sb, Shapero, Pa, Shearer, Sd, Sheikh, Sq, Shepherd, Ts, Sher, Er, Sher, Ld, Short, Bh, Silas, Pe, Alvey, Jc, Silverfield, Jc, Simon, Sj, Sitar, S, Skoner, Dp, Smallow, Sa, Smart, Ba, Smith, Ca, Smith, Ke, Smith, Sk, Snyders, Gc, Soong, W, Soufer, J, Spangenthal, S, Stahlman, Je, Steele, Lg, Stegemoller, Rk, Stocks, J, Storms, Ww, Suen, J, Surowitz, Rz, Swauger, Jr, Taber, La, Tan, Ae, Pratt, Se, Tanus, T, Tarpay, Mm, Tarshis, Ga, Tenney, Jw, Tilghman, Kg, Trevino, Me, Troyan, Be, Twiddy, Sk, Updegrove, Jd, Urval, Kr, Uusinarkaus, Kt, Vaela, R, Van Cleeff, M, Varano, S, Vo, Qd, Wainz, Rj, Wald, Ja, Wall, Sj, Wasserman, Rl, Weinstein, Dl, Welker, Ja, Wellmon, B 2nd, Wells, T, Wenocur, Hs, Williams, Dl, Williams, Sl, Win, Ph, Wingo, Td, Wisman PP Jr, Wyszomierski, Da, Yamada, Hm, Yarows, S, Yunger TM Jr, Ziering, Rw., the AUSTRI Investigators, Stempel, D., Raphiou, I., Kral, K., Yeakey, A., Emmett, A., Prazma, C., Buaron, K., and Pascoe, S. Scichilone N tra i collaboratori

Subjects
Male, asthma, serious events, fluticasone, salmeterol, AUSTRI, Exacerbation, Intention to Treat Analysi, INHALED CORTICOSTEROIDS, Severity of Illness Index, law.invention, 0302 clinical medicine, Randomized controlled trial, law, immune system diseases, Ús terapèutic, Broncodilatadors, 030212 general & internal medicine, Child, Fluticasone, RISK, ACTING BETA-AGONISTS, EXACERBATIONS, METAANALYSIS, MORTALITY, SAFETY, DEATH, FDA, Medicine (all), Hazard ratio, General Medicine, Bronchodilator agents, Middle Aged, Fluticasone-Salmeterol Drug Combination, Bronchodilator Agents, Intention to Treat Analysis, Anesthesia, Female, Salmeterol, medicine.drug, Human, Adult, medicine.medical_specialty, Adolescent, Settore MED/10 - Malattie Dell'Apparato Respiratorio, Fluticasone propionate, 03 medical and health sciences, Double-Blind Method, Internal medicine, Administration, Inhalation, medicine, Humans, Asma, Bronchodilator Agent, Asthma, Aged, Proportional Hazards Models, business.industry, Therapeutic use, medicine.disease, respiratory tract diseases, 030228 respiratory system, Fluticasone Propionate, Salmeterol Xinafoate Drug Combination, Proportional Hazards Model, business
Abstract

BACKGROUND The safe and appropriate use of long-acting beta-agonists (LABAs) for the treatment of asthma has been widely debated. In two large clinical trials, investigators found a potential risk of serious asthma-related events associated with LABAs. This study was designed to evaluate the risk of administering the LABA salmeterol in combination with an inhaled glucocorticoid, fluticasone propionate. METHODS In this multicenter, randomized, double-blind trial, adolescent and adult patients (age, ≥12 years) with persistent asthma were assigned to receive either fluticasone with salmeterol or fluticasone alone for 26 weeks. All the patients had a history of a severe asthma exacerbation in the year before randomization but not during the previous month. Patients were excluded from the trial if they had a history of lifethreatening or unstable asthma. The primary safety end point was the first serious asthma-related event (death, endotracheal intubation, or hospitalization). Noninferiority of fluticasone–salmeterol to fluticasone alone was defined as an upper boundary of the 95% confidence interval for the risk of the primary safety end point of less than 2.0. The efficacy end point was the first severe asthma exacerbation. RESULTS Of 11,679 patients who were enrolled, 67 had 74 serious asthma-related events, with 36 events in 34 patients in the fluticasone–salmeterol group and 38 events in 33 patients in the fluticasone-only group. The hazard ratio for a serious asthmarelated event in the fluticasone–salmeterol group was 1.03 (95% confidence interval [CI], 0.64 to 1.66), and noninferiority was achieved (P = 0.003). There were no asthma-related deaths; 2 patients in the fluticasone-only group underwent asthmarelated intubation. The risk of a severe asthma exacerbation was 21% lower in the fluticasone–salmeterol group than in the fluticasone-only group (hazard ratio, 0.79; 95% CI, 0.70 to 0.89), with at least one severe asthma exacerbation occurring in 480 of 5834 patients (8%) in the fluticasone–salmeterol group, as compared with 597 of 5845 patients (10%) in the fluticasone-only group (P

Published
2016

45. 3D photonic crystals from highly monodisperse FRET-based red luminescent PMMA spheres

Author

Cefe López, Juan F. Galisteo-López, Marta Ibisate, Aurelio Arnedillo Muñoz, Ministerio de Economía y Competitividad (MINECO). España, and Comunidad Autónoma de Madrid

Subjects
Materials science, business.industry, Dispersity, Analytical chemistry, Physics::Optics, Bragg's law, General Chemistry, 7. Clean energy, Polymerization, Materials Chemistry, Optoelectronics, Photonics, Luminescence, Spectroscopy, business, Visible spectrum, Photonic crystal
Abstract

© The Royal Society of Chemistry 2015. Red-luminescent PMMA spheres containing a Förster resonance energy transfer (FRET) pair were synthesized via a two-step polymerization method. Two reaction parameters, time and monomer volume, are scanned in order to tune the sphere diameter in the 250-500 nm range. Further the polydispersity of the spheres is kept low, at ca. 3%, regardless of sphere diameter or dye concentration. A thorough optical characterization via spectroscopy and time resolved measurements shows a FRET efficiency of over 40% before concentration quenching effects take place, allowing for a precise tuning of their emission in the red region of the visible spectrum. The high quality of these spheres makes them suitable to fabricate self-assembled 3D photonic crystals which act as photonic environment to modify the spectral properties of the FRET pair via Bragg diffraction. This journal is

Published
2015

46. Efectos de la oxigenoterapia líquida portátil sobre la deambulación

Author

A. León Jiménez, J. A. Córdoba Doña, A. Arnedillo Muñoz, J.J. Fernández Berni, and A. Rosano Romero

Subjects
Pulmonary and Respiratory Medicine, business.industry, Medicine, business, Humanities
Abstract

Los efectos de la oxigenoterapia liquida portatil (OLP) sobre la deambulacion, con el esfuerzo que supone cargar con el dispositivo portatil, no estan totalmente aclarados. Nuestro objetivo ha sido evaluar la repercusion de la OLP sobre la deambulacion, utilizando para ello la prueba de marcha de 6 minutos. Se estudiaron 30 pacientes en tratamiento con oxigenoterapia domiciliaria (OD), a los que se les realizaron una gasometria arterial basal, una espirometria y tres pruebas de marcha de 6 minutos, la primera basal, y posteriormente aleatorizadas y cruzadas, una con aire comprimido simulando oxigeno y otra con oxigeno liquido (OL). Durante la realizacion de las pruebas, se midieron la frecuencia cardiaca maxima, la distancia recorrida, la disnea mediante la escala de Borg, la saturacion de oxigeno (SatO2) media y el tiempo que los pacientes estuvieron por encima del 89% de saturacion. Comparando las pruebas basales con las realizadas con aire comprimido, no se observaron mejorias en ninguno de los parametros evaluados. Sin embargo, si se observo un aumento de la distancia recorrida en las pruebas con OL, comparadas con las basales, asi como la correccion de la SatO2 al flujo prescrito. La disnea no se modifico significativamente.

Published
1999
Full Text
View/download PDF

48. The underdiagnosis of Chronic Obstructive Pulmonary disease in women. Another pending task?

Author

Aurelio Arnedillo Muñoz

Subjects
Male, medicine.medical_specialty, COPD, business.industry, Pulmonary disease, General Medicine, medicine.disease, respiratory tract diseases, Pulmonary Disease, Chronic Obstructive, Quality of life, Internal medicine, Epidemiology, medicine, Anxiety, Humans, Female, Risk factor, medicine.symptom, business, Developed country, Depression (differential diagnoses)
Abstract

The prevalence of Chronic Obstructive Pulmonary disease (COPD) in various epidemiological studies conducted in Europe is between 5% and 11%, with a higher prevalence in men than in women. This can be explained by the higher prevalence of smoking in males, which is the principal risk factor associated with COPD, at least in industrialised countries.1 However, in recent years we have witnessed an increase in the prevalence of COPD in women, due to their incorporation to smoking in the 1960–1970s in developed countries,2 (incorporation which has been somewhat later in Spain) and the exposure to other risk factors such as the combustion of biomass products, especially in developing countries.3 In fact, in the year 2000 in the United States, mortality due to COPD in women exceeded that in men for the first time.4 From a symptomatic point of view, women with COPD have more dyspnoea, a higher prevalence of anxiety and depression and lower quality of life with respect to men for the same lung function and intensity of smoking, and more often have a chronic bronchitislike phenotype, while males are more likely to have an emphysema phenotype. Furthermore, the loss of lung function that they experience may be greater than in men, and they have more difficulty in quitting smoking.3,4 Despite the increase in the prevalence of COPD in women, underdiagnosis in females is usually greater than in men. A clear example of this underdiagnosis was shown by Chapman et al.5 In their study, they showed that when hypothetical cases of smokers with dyspnoea and cough were presented to Primary Care physicians, in which the only parameters that varied were sex and age, the probability of diagnosing COPD in men was greater than in women (58% vs 42%, P

Published
2013

Catalog

Books, media, physical & digital resources
See catalog results