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1. Quantum state control of a Bose-Einstein condensate in an optical lattice

Author

Dupont, N., Chatelain, G., Gabardos, L., Arnal, M., Billy, J., Peaudecerf, B., Sugny, D., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases
Abstract

We report on the efficient design of quantum optimal control protocols to manipulate the motional states of an atomic Bose-Einstein condensate (BEC) in a one-dimensional optical lattice. Our protocols operate on the momentum comb associated with the lattice. In contrast to previous works also dealing with control in discrete and large Hilbert spaces, our control schemes allow us to reach a wide variety of targets by varying a single parameter, the lattice position. With this technique, we experimentally demonstrate a precise, robust and versatile control: we optimize the transfer of the BEC to a single or multiple quantized momentum states with full control on the relative phase between the different momentum components. This also allows us to prepare the BEC in a given eigenstate of the lattice band structure, or superposition thereof.

Published
2021
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2. Observation and control of quantized scattering halos

Author

Chatelain, G., Dupont, N., Arnal, M., Brunaud, V., Billy, J., Peaudecerf, B., Schlagheck, P., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases, Quantum Physics
Abstract

We investigate the production of s-wave scattering halos from collisions between the momentum components of a Bose-Einstein condensate released from an optical lattice. The lattice periodicity translates in a momentum comb responsible for the quantization of the halos' radii. We report on the engineering of those halos through the precise control of the atom dynamics in the lattice: we are able to specifically enhance collision processes with given center-of-mass and relative momenta. In particular, we observe quantized collision halos between opposite momenta components of increasing magnitude, up to 6 times the characteristic momentum scale of the lattice., Comment: 11 pages, 7 figures

Published
2020
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3. Chaos-assisted tunneling resonances in a synthetic Floquet superlattice

Author

Arnal, M., Chatelain, G., Martinez, M., Dupont, N., Giraud, O., Ullmo, D., Georgeot, B., Lemarié, G., Billy, J., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases, Quantum Physics
Abstract

The field of quantum simulation, which aims at using a tunable quantum system to simulate another, has been developing fast in the past years as an alternative to the all-purpose quantum computer. In particular, the use of temporal driving has attracted a huge interest recently as it was shown that certain fast drivings can create new topological effects, while a strong driving leads to e.g. Anderson localization physics. In this work, we focus on the intermediate regime to observe a quantum chaos transport mechanism called chaos-assisted tunneling which provides new possibilities of control for quantum simulation. Indeed, this regime generates a rich classical phase space where stable trajectories form islands surrounded by a large sea of unstable chaotic orbits. This mimics an effective superlattice for the quantum states localized in the regular islands, with new controllable tunneling properties. Besides the standard textbook tunneling through a potential barrier, chaos-assisted tunneling corresponds to a much richer tunneling process where the coupling between quantum states located in neighboring regular islands is mediated by other states spread over the chaotic sea. This process induces sharp resonances where the tunneling rate varies by orders of magnitude over a short range of parameters. We experimentally demonstrate and characterize these resonances for the first time in a quantum system. This opens the way to new kinds of quantum simulations with long-range transport and new types of control of quantum systems through complexity.

Published
2020
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4. Beyond effective Hamiltonians: micromotion of Bose Einstein condensates in periodically driven optical lattices

Author

Arnal, M., Chatelain, G., Cabrera-Gutiérrez, C., Fortun, A., Michon, E., Billy, J., Schlagheck, P., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases, Quantum Physics
Abstract

We investigate a Bose Einstein condensate held in a 1D optical lattice whose phase undergoes a fast oscillation using a statistical analysis. The averaged potential experienced by the atoms boils down to a periodic potential having the same spatial period but with a renormalized depth. However, the atomic dynamics also contains a \emph{micromotion} whose main features are revealed by a Kolmorogov-Smirnov analysis of the experimental momentum distributions. We furthermore discuss the impact of the micromotion on a quench process corresponding to a proper sudden change of the driving amplitude which reverses the curvature of the averaged potential., Comment: Our preprint 1804.02147v1 [cond-mat.quant-gas] has triggered this study dedicated to the micromotion hidden behind effective Hamiltonians generated by fast time-modulation of a parameter

Published
2019
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6. Direct cooling in an optical lattice by amplitude modulation

Author

Arnal, M., Brunaud, V., Chatelain, G., Cabrera-Gutiérrez, C., Michon, E., Cheiney, P., Billy, J., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases
Abstract

We report on a generic cooling technique for atoms trapped in optical lattices. It consists in modulating the lattice depth with a proper frequency sweeping. This filtering technique removes the most energetic atoms, and provides with the onset of thermalization a cooling mechanism reminiscent of evaporative cooling. However, the selection is here performed in quasi-momentum space rather than in position space. Interband selection rules are used to protect the population with a zero quasi-momentum, namely the Bose Einstein condensate. Direct condensation of thermal atoms in an optical lattice is also achieved with this technique. It offers an interesting complementary cooling mechanism for quantum simulations performed with quantum gases trapped in optical lattices., Comment: 5 pages, 3 figures

Published
2018
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7. Resonant excitations of a Bose Einstein condensate in an optical lattice

Author

Cabrera-Gutiérrez, C., Michon, E., Arnal, M., Brunaud, V., Kawalec, T., Billy, J., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases
Abstract

We investigate experimentally a Bose Einstein condensate placed in a 1D optical lattice whose phase or amplitude is modulated in a frequency range resonant with the first bands of the band structure. We study the combined effect of the strength of interactions and external confinement on the 1 and 2-phonon transitions. We identify lines immune or sensitive to atom-atom interactions. Experimental results are in good agreement with numerical simulations. Using the band mapping technique, we get a direct access to the populations that have undergone $n$-phonon transitions for each modulation frequency.

Published
2018
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8. Fast phase-modulated optical lattice for wave packet engineering

Author

Cabrera-Gutiérrez, C., Fortun, A., Michon, E., Brunaud, V., Arnal, M., Billy, J., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases, Quantum Physics
Abstract

We investigate experimentally a Bose Einstein condensate placed in a 1D optical lattice whose phase is modulated at a frequency large compared to all characteristic frequencies. As a result, the depth of the periodic potential is renormalized by a Bessel function which only depends on the amplitude of modulation, a prediction that we have checked quantitatively using a careful calibration scheme. This renormalization provides an interesting tool to engineer in time optical lattices. For instance, we have used it to perform simultaneously a sudden $\pi$-phase shift (without phase residual errors) combined with a change of lattice depth, and to study the subsequent out-of-equilibrium dynamics., Comment: 5 pages, 2 figures

Published
2018

9. Ultrarobust calibration of an optical lattice depth based on a phase shift

Author

Cabrera-Gutiérrez, C., Michon, E., Brunaud, V., Kawalec, T., Fortun, A., Arnal, M., Billy, J., and Guéry-Odelin, D.

Subjects
Condensed Matter - Quantum Gases, Quantum Physics
Abstract

We report on a new method to calibrate the depth of an optical lattice. It consists in triggering the intrasite dipole mode of the cloud by a sudden phase shift. The corresponding oscillatory motion is directly related to the intraband frequencies on a large range of lattice depths. Remarkably, for a moderate displacement, a single frequency dominates this oscillation for the zeroth and first order interference pattern observed after a sufficiently long time-of-flight. The method is robust against atom-atom interactions and the exact value of the extra external confinement of the initial trapping potential., Comment: 7 pages, 6 figures

Published
2018
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10. Out-of-equilibrium dynamics of a Bose Einstein condensate in a periodically driven band system

Author

Michon, E., Cabrera-Gutierrez, C., Fortun, A., Berger, M., Arnal, M., Brunaud, V., Billy, J., Petitjean, C., Schlagheck, P., and Guery-Odelin, D.

Subjects
Condensed Matter - Quantum Gases
Abstract

We report on the out-of-equilibrium dynamics of a Bose-Einstein condensate (BEC) placed in an optical lattice whose phase is suddenly modulated. The frequency and the amplitude of modulation are chosen to ensure a negative renormalized tunneling rate. Under these conditions, staggered states are nucleated by a spontaneous four wave mixing mechanism. The nucleation time is experimentally studied as a function of the renormalized tunnel rate, the atomic density and the modulation frequency. Our results are quantitatively well accounted for by a Truncated Wigner approach and reveal the nucleation of gap solitons after the quench. We discuss the role of quantum versus thermal fluctuations in the nucleation process and experimentally address the limit of the effective Hamiltonian approach.

Published
2017
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12. Compliance with the clinical guidelines for managing asthma by primary care physicians: An ambispective observational study

Author

Abedianzadeh Timar, Mohsen, Acha Domínguez, Jesús, Aguaviva Bascuñana, Jesus, Aguilar Martín, Ignacio, Ales Conejo, Francisco Ignacio, Alfaro González, Juan Vicente, Alfonso Landa, Patricia, Altés Boronat, Andrés, Álvarez Arriero, Jesús Joaquín, Álvarez Rojo, Juan Ángel, Vidal German, Allut, Amaro Cendón, Jesús, Amiano Arregui, María Teresa, Angulo Vallejo, Esther, Anton Álvarez, Juan José, Anton Ortega, Javier, Arconada Perez, Ana, Ardiaca Burgués, Lidia, Armario Vázquez, Juan Manuel, Arroyo Cubeiro, Amador, Aso Mendialdea, Koldo, Attardo, Francesca, Ávila de Tomás, José Francisco, Avinent Arnal, M. Jesús, Aznar Aguilar, Francisco, Aznar Tejero, Pilar, Baena Montilla, Emilio, Baeza López, José María, Barón Carrillo, Juan José, Bartolomé Resano, Rafael, Becoña de la Torre, Francisco, Benavent Martín, Isabel, Benedí Sánchez, María Teresa, Berrocal del Brío, José, Blanco Delgado, Antonio, Bleda Cano, Jesús, Boladeras Sabater, Josep, Bolívar Mantilla, Zenaida, Brito Brito, Elisenda, Burgos Parra, M. Rosario, Buxadé Martí, Isaac, Caballero Garcia, Juan Carlos, Cabañas Enríquez, Luis Fernando, Calviño Cerqueiro, Marcelino, Calvo Fernández, Juan, Calle Velles, Felipe, Camaro Zafra, Beatriz, Campomar Quetlas, Jaume, Capitán Jurado, Mónica, Cárdenas Joyanes, Dolores, Carles Bueso, Gonzalo, Carvajal Puente, Cristina, Casado Rodriguez, Cristina, Casanova García, Carlos, Castellà Cahiz, Santiago, Castellà Cuesta, Cristina, Castellano Martínez, Manuel Antonio, Catalán Félez, Rafael, Cavada García, Miguel Ángel, Cavada Velasco, Antonio, Cidra Gordillo, Jose Luis, Clemente Garcia, Julia, Collada Jiménez, José Luis, Cornejo Figueroa, Andrés, Cornejo Rodríguez, Roberto, Cuevas Morales, Julio, Curado-Moliní Álvarez, María Jesús, Daviña Romero, Susana, de Arriba Muñoz, Leonor, de la Flor Benítez, Manuel, de la Poza Abad, Mariam, de los Bueis Martinez, Gustavo, de Miguel Márquez, María Pía, de Pablo Martín, Jesús, Delgado Mora, Manuel, Díaz Mateo, Joaquín, Díaz Saborido, Almudena, Díez-Caballero Murua, María, Doganis Peppas, Constantino, Domínguez Alonso, Gonzalo, Domínguez Ávila, Julián, Domínguez González, María Nieves, Domínguez Hernández, María Isabel, Dosantos Hernández, Javier Oscar, Dueñas Buey, Aurelio, Eiris Cambre, M. Jesús, El Wafa Vaca, Yussef Abu, Enseñat Sanchez, Antonio Alberto, Esquerra Tuñí, Eulalia, Esteve Ribelles, José María, Estevez Barrondo, José Antonio, Estraviz Vidal, M. Dolores, Fajardo Salguero, Rosa María, Felipe Olivero, José Francisco, Fernández Bujía, María Luisa, Fernández Cano, Patricia, Fernández Cañaveras, M. Isabel, Fernández Fernández, Carmen, Fernández García, José Manuel, Fernández Gómez, Patricia, Fernández González, José María, Fernández Gutiérrez Denia, Irene, Fernández Huelga, M. Esther, Fernández Martin, Yolanda, Fernández Navarro, Francisco, Fernández Revuelta, Araceli, Fernández Toro, José María, Fernández-Pacheco Corchado, Luis María, Ferrándiz Miquel, Joaquín, Ferrari Piquero, Carmen, Ferrer García-Borrás, José María, Gago Fernandez, Carlos, Gago Gómez, Fernando, Galera de Ulierte, Luz Inmaculada, Gallegos Juárez, Ingrid, Garceran Azorín-Gómez, José Enrique, Garcés Romero, Carmen, García Alonso, Francisco Javier, García Cabana, Andres A., García Cano, Josefa, García Ceballos, Victoria Gema, García de Francisco, Sara, García Fuentes, Francisco, García Vázquez, Yolanda, García Collado, Sergio, García-Giralda Ruiz, Luis, García-Serrano Jiménez, Beatriz, Garrido Pérez, Montse, Garro Mendiolagaray, Jon Kepa, Gea Villar, Jorge, Genover Llimona, Teresa, Gil Moreno, Felipe, Gil Pastor, Javier Julián, Gispert Servitje, Adrià, Godoy García, Isidro Domingo, Gómez Martínez, Gabriel, Gómez Sanmiguel, Francisco Javier, Gómez Yelo, Jose, Gonzales Flores, Pedro Alejandro, González Hernández, Luis, Gonzálvez Rey, Jaime, Gorgues Comas, Roberto, Guillen Anton, María Victoria, Gutiérrez Almarza, Miguel Ángel, Gutiérrez Esteban, Jose Luis, Guzón Centeno, Marta, Hermoso Sabio, Antonio, Hernández Castellanos, Manuel, Hernández Pérez, Ana, Herranz Alfaro, Alfredo, Hinojosa Díaz, José Francisco, Iglesias Fernández, José, Intxausti Erdoiza, Iñaki, Izarra Páramo, Miriam, Jiménez Marcen, Ana Isabel, Jimeno Bernad, Rosa María, Jover Andreu, María José, Juan Alcaraz, Francisco Emilio, Labrador Arranz, Esther, Laencina López, Salvador, Lapuente Troncoso, Elena, Latorre Cásedas, Montserrat, Leal Hernández, Mariano, Ledesma Santiago, Lourdes, Lillo Bravo, Francisco Javier, Lizarribar Sans, Marta, Lobato Martínez, Rocío, López Alonso, Emilia Begoña, López Cruz, Urbano, López Chamon, Silvia, López de Viñaspre Muguerza, Ana Isabel, López Herranz, Ana Belén, López Marina, Víctor, López Ortiz, Francisco, López Silva, Mª Carmen, Lucas Boronat, José María, Lugo Ramos, Héctor Leonardo, Lutz Garcia, Erika, Llosa Ventura, Juan Luis, Macías Corbacho, Antonio, Magem Niubo, Juan, Mancilla las Heras, Diego, Maneu Juan, Alfonso, Manzano Jiménez, José, Mañes Vicente, Pascual, Maranges Comella, María Isabel, Marco Segarra, Emilio, María Tablado, Miguel Ángel, Marlasca Garcia, Juan Carlos, Martí Canales, Juan Carlos, Martín Clos, José, Martín de la Vega, Saúl, Martín Ruiz Lavela, Francisco, Martinez Aparicio, M. Desamparada, Martínez de Carnero Calzada, Rafael, Martinez González, Agustín, Martínez Jiménez, Juan Manuel, Martínez Laguna, Daniel, Martínez Mayora, María Teresa, Martinez Merodio, Pilar, Martínez Novoa, Luis, Martínez Ortega, Mireia, Martínez Rojas, Francisco, Martínez Rossello, Antonio, Meijome Sánchez, María del Carmen, Méndez-Cabeza Velázquez, Jesús, Méndez Maiques, Jose María, Misericordia Garcia, Santiago, Molina Cabildo, José, Molina Martínez, Luis Javier, Monge García, José Manuel, Montes Belloso, María Ester, Moreno Molina, Susana, Motos Díaz, Patrocinio, Mourelo Cereijo, Marta, Moyá Amengual, Ana, Muñoz Ruiz, Pedro José, Narváez Martín, José María, Navarro Luna, Juan Luis, Navarro Tarin, Fernando, Nicolau Grego, Jorge, Niño Azcarate, Cristina, Nova Alvarez, José, Núñez Cordón, Juan Carlos, Olagorta de Prado, Asunción, Oros Espinosa, Vicente, Ortega Pinilla, M. Concepción, Ortega Ruiz, María Paz, Osca Pellicer, David, Otamendi Murillo, Ana, Otero Mata, Manuel, Ouzzine Marín, Myriam, Paja Fano, Eduardo, Palacio Gonzalez, Domingo, Palau Oñate, Rosario, Pazos Garrido, Néstor, Pecharroman Fuente, Virginia, Peña Rosa, Jose Manuel, Peral Cabot, Francisco Javier, Pérez Barreto, Iván Yamir, Pérez Caballero, Isabel, Pérez Fernández, Maria del Carmen, Pérez Fernández, Antonio Luis, Pérez Gutiérrez, Esteban, Pérez Rios, Manuel, Petit Sánchez, José Manuel, Piñero Acin, Maria José, Pozuelos Estrada, Jerónimo, Prieto Cid, Manuel, Prieto Gutiérrez, Joaquín, Raga Casasus, José Vicente, Ramírez Espinosa, Manuel Francisco, Rebollo Hernamperez, Eduardo, Rey Rañal, Alejandra, Ribelles Villalba, Ricardo Sagunto, Rodas Peral, José Antonio, Rodil Martinez, Aurora, Rodríguez, Manuel, José, Rodríguez Calcaño, Enrique Emperador, Rodríguez Fernandez, Concepción, Rodríguez Galipienzo, José Miguel, Rodriguez Lois, Miguel Ángel, Rodríguez Partida, José Antonio, Roel Conde, Jaime, Roman Rodriguez, Miguel, Romero Caballero, Gregorio, Romero Hernández, Pedro, Rosales García, Luis Miguel, Royo del Río, Manuel, Ruiz Gomes, María, Ruiz Moruno, Francisco Javier, Ruiz Perez, Jaime, Salinero Acevedo, José Ramón, Sánchez Apresa, Manuel, Sanchez Calavera, María Antonia, Sánchez Garcia, Fernando, Sánchez Gutiérrez, Miguel Ángel, Sánchez Ibáñez, Antonio, Sánchez López, Eugenio, Sánchez Loureiro, Manuel, Sanchez Lozano, Ana, Sánchez Romero, Gregorio, Sánchez Ruano, Fernando, Sánchez Ruiz, Gabriela, Sánchez Sanchez, Froilán, Santiago Ayarza, Asier, Santos Bermejo, Juan Antonio, Sanz de Miguel, Elena, Sanz Sanz, Marta, Sanz Velasco, Carmelina, Sauco Colón, Inmaculada, Sedano García, José Ignacio, Segovia Castro, Luis, Senan Sanz, María Rosa, Serra Cabot, Pere, Serra Gallego, Marta, Serrano Tomás, Daniel, Sesma Aisa, Francisco Tomás, Seuba Garcés, Jordi, Soler David, Vicente, Soria Mesa, Jose Antonio, Sosa Álvarez, César, Suárez Pérez, María, Tafalla Martín, Antonio, Tamayo Ferriol, Thaimi, Tamayo Marín, José Luis, Thalamas Atienza, Juan Aitor, Toledo Muñoz, Ana María, Tomás-Rodo Massaneda, Lluis Miquel, Torres de Castro, Milko, Torres Martínez, Francisco Javier, Tovar Álvarez, Enrique, Ugarte Goñi, Ainhoa, Valle González, Irene, Vasco Mahillo, Sonia, Enrique José, Vázquez Seijas, Vericat Roure, Antonio, Villalba Parrado, Arelis, Villanueva Rebollo, Jose María, Villar Valgañon, Ricardo, Villena Masegosa, Vicente, Viñals Gigena, Montserrat, Viñas Cabrera, Lydia, Zarco Pinteño, David, Roman-Rodriguez, M., Molina-Paris, J., and Fernandez Sanchez, A.

Published
2021
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13. Seguimiento de las guías españolas para el manejo del asma por el médico de atención primaria: un estudio observacional ambispectivo

Author

Abedianzadeh Timar, Mohsen, Acha Domínguez, Jesús, Aguaviva Bascuñana, Jesus, Aguilar Martín, Ignacio, Ales Conejo, Francisco Ignacio, Alfaro González, Juan Vicente, Alfonso Landa, Patricia, Altés Boronat, Andrés, Álvarez Arriero, Jesús Joaquín, Álvarez Rojo, Juan Ángel, Vidal German, Allut, Amaro Cendón, Jesús, Amiano Arregui, María Teresa, Angulo Vallejo, Esther, Anton Álvarez, Juan José, Anton Ortega, Javier, Arconada Perez, Ana, Ardiaca Burgués, Lidia, Armario Vázquez, Juan Manuel, Arroyo Cubeiro, Amador, Aso Mendialdea, Koldo, Attardo, Francesca, Ávila de Tomás, José Francisco, Avinent Arnal, M. Jesús, Aznar Aguilar, Francisco, Aznar Tejero, Pilar, Baena Montilla, Emilio, Baeza López, José María, Barón Carrillo, Juan José, Bartolomé Resano, Rafael, Becoña de la Torre, Francisco, Benavent Martín, Isabel, Benedí Sánchez, María Teresa, Berrocal del Brío, José, Blanco Delgado, Antonio, Bleda Cano, Jesús, Boladeras Sabater, Josep, Bolívar Mantilla, Zenaida, Brito Brito, Elisenda, Burgos Parra, M. Rosario, Buxadé Martí, Isaac, Caballero Garcia, Juan Carlos, Cabañas Enríquez, Luis Fernando, Calviño Cerqueiro, Marcelino, Calvo Fernández, Juan, Calle Velles, Felipe, Camaro Zafra, Beatriz, Campomar Quetlas, Jaume, Capitán Jurado, Mónica, Cárdenas Joyanes, Dolores, Carles Bueso, Gonzalo, Carvajal Puente, Cristina, Casado Rodriguez, Cristina, Casanova García, Carlos, Castellà Cahiz, Santiago, Castellà Cuesta, Cristina, Castellano Martínez, Manuel Antonio, Catalán Félez, Rafael, Cavada García, Miguel Ángel, Cavada Velasco, Antonio, Cidra Gordillo, Jose Luis, Clemente Garcia, Julia, Collada Jiménez, José Luis, Cornejo Figueroa, Andrés, Cornejo Rodríguez, Roberto, Cuevas Morales, Julio, Curado-Moliní Álvarez, María Jesús, Daviña Romero, Susana, de Arriba Muñoz, Leonor, de la Flor Benítez, Manuel, de la Poza Abad, Mariam, de los Bueis Martinez, Gustavo, de Miguel Márquez, María Pía, de Pablo Martín, Jesús, Delgado Mora, Manuel, Díaz Mateo, Joaquín, Díaz Saborido, Almudena, Díez-Caballero Murua, María, Doganis Peppas, Constantino, Domínguez Alonso, Gonzalo, Domínguez Ávila, Julián, Domínguez González, María Nieves, Domínguez Hernández, María Isabel, Dosantos Hernández, Javier Oscar, Dueñas Buey, Aurelio, Eiris Cambre, M. Jesús, El Wafa Vaca, Yussef Abu, Enseñat Sanchez, Antonio Alberto, Esquerra Tuñí, Eulalia, Esteve Ribelles, José María, Estevez Barrondo, José Antonio, Estraviz Vidal, M. Dolores, Fajardo Salguero, Rosa María, Felipe Olivero, José Francisco, Fernández Bujía, María Luisa, Fernández Cano, Patricia, Fernández Cañaveras, M. Isabel, Fernández Fernández, Carmen, Fernández García, José Manuel, Fernández Gómez, Patricia, Fernández González, José María, Fernández Gutiérrez Denia, Irene, Fernández Huelga, M. Esther, Fernández Martin, Yolanda, Fernández Navarro, Francisco, Fernández Revuelta, Araceli, Fernández Toro, José María, Fernández-Pacheco Corchado, Luis María, Ferrándiz Miquel, Joaquín, Ferrari Piquero, Carmen, Ferrer García-Borrás, José María, Gago Fernandez, Carlos, Gago Gómez, Fernando, Galera de Ulierte, Luz Inmaculada, Gallegos Juárez, Ingrid, Garceran Azorín-Gómez, José Enrique, Garcés Romero, Carmen, García Alonso, Francisco Javier, García Cabana, Andres A., García Cano, Josefa, García Ceballos, Victoria Gema, García de Francisco, Sara, García Fuentes, Francisco, García Vázquez, Yolanda, García Collado, Sergio, García-Giralda Ruiz, Luis, García-Serrano Jiménez, Beatriz, Garrido Pérez, Montse, Garro Mendiolagaray, Jon Kepa, Gea Villar, Jorge, Genover Llimona, Teresa, Gil Moreno, Felipe, Gil Pastor, Javier Julián, Gispert Servitje, Adrià, Godoy García, Isidro Domingo, Gómez Martínez, Gabriel, Gómez Sanmiguel, Francisco Javier, Gómez Yelo, Jose, Gonzales Flores, Pedro Alejandro, González Hernández, Luis, Gonzálvez Rey, Jaime, Gorgues Comas, Roberto, Guillen Anton, María Victoria, Gutiérrez Almarza, Miguel Ángel, Gutiérrez Esteban, Jose Luis, Guzón Centeno, Marta, Hermoso Sabio, Antonio, Hernández Castellanos, Manuel, Hernández Pérez, Ana, Herranz Alfaro, Alfredo, Hinojosa Díaz, José Francisco, Iglesias Fernández, José, Intxausti Erdoiza, Iñaki, Izarra Páramo, Miriam, Jiménez Marcen, Ana Isabel, Jimeno Bernad, Rosa María, Jover Andreu, María José, Juan Alcaraz, Francisco Emilio, Labrador Arranz, Esther, Laencina López, Salvador, Lapuente Troncoso, Elena, Latorre Cásedas, Montserrat, Leal Hernández, Mariano, Ledesma Santiago, Lourdes, Lillo Bravo, Francisco Javier, Lizarribar Sans, Marta, Lobato Martínez, Rocío, López Alonso, Emilia Begoña, López Cruz, Urbano, López Chamon, Silvia, López de Viñaspre Muguerza, Ana Isabel, López Herranz, Ana Belén, López Marina, Víctor, López Ortiz, Francisco, López Silva, M.a Carmen, Lucas Boronat, José María, Lugo Ramos, Héctor Leonardo, Lutz Garcia, Erika, Llosa Ventura, Juan Luis, Macías Corbacho, Antonio, Magem Niubo, Juan, Mancilla las Heras, Diego, Maneu Juan, Alfonso, Manzano Jiménez, José, Mañes Vicente, Pascual, Maranges Comella, María Isabel, Marco Segarra, Emilio, María Tablado, Miguel Ángel, Marlasca Garcia, Juan Carlos, Martí Canales, Juan Carlos, Martín Clos, José, Martín de la Vega, Saúl, Martín Ruiz Lavela, Francisco, Martinez Aparicio, M. Desamparada, Martínez de Carnero Calzada, Rafael, Martinez González, Agustín, Martínez Jiménez, Juan Manuel, Martínez Laguna, Daniel, Martínez Mayora, María Teresa, Martinez Merodio, Pilar, Martínez Novoa, Luis, Martínez Ortega, Mireia, Martínez Rojas, Francisco, Martínez Rossello, Antonio, Meijome Sánchez, María del Carmen, Méndez-Cabeza Velázquez, Jesús, Méndez Maiques, Jose María, Misericordia Garcia, Santiago, Molina Cabildo, José, Molina Martínez, Luis Javier, Monge García, José Manuel, Montes Belloso, María Ester, Moreno Molina, Susana, Motos Díaz, Patrocinio, Mourelo Cereijo, Marta, Moyá Amengual, Ana, Muñoz Ruiz, Pedro José, Narváez Martín, José María, Navarro Luna, Juan Luis, Navarro Tarin, Fernando, Nicolau Grego, Jorge, Niño Azcarate, Cristina, Nova Alvarez, José, Núñez Cordón, Juan Carlos, Olagorta de Prado, Asunción, Oros Espinosa, Vicente, Ortega Pinilla, M. Concepción, Ortega Ruiz, María Paz, Osca Pellicer, David, Otamendi Murillo, Ana, Otero Mata, Manuel, Ouzzine Marín, Myriam, Paja Fano, Eduardo, Palacio Gonzalez, Domingo, Palau Oñate, Rosario, Pazos Garrido, Néstor, Pecharroman Fuente, Virginia, Peña Rosa, Jose Manuel, Peral Cabot, Francisco Javier, Pérez Barreto, Iván Yamir, Pérez Caballero, Isabel, Pérez Fernández, Maria del Carmen, Pérez Fernández, Antonio Luis, Pérez Gutiérrez, Esteban, Pérez Rios, Manuel, Petit Sánchez, José Manuel, Piñero Acin, Maria José, Pozuelos Estrada, Jerónimo, Prieto Cid, Manuel, Prieto Gutiérrez, Joaquín, Raga Casasus, José Vicente, Ramírez Espinosa, Manuel Francisco, Rebollo Hernamperez, Eduardo, Rey Rañal, Alejandra, Ribelles Villalba, Ricardo Sagunto, Rodas Peral, José Antonio, Rodil Martinez, Aurora, Rodríguez, Manuel, José, Rodríguez Calcaño, Enrique Emperador, Rodríguez Fernandez, Concepción, Rodríguez Galipienzo, José Miguel, Rodriguez Lois, Miguel Ángel, Rodríguez Partida, José Antonio, Roel Conde, Jaime, Roman Rodriguez, Miguel, Romero Caballero, Gregorio, Romero Hernández, Pedro, Rosales García, Luis Miguel, Royo del Río, Manuel, Ruiz Gomes, María, Ruiz Moruno, Francisco Javier, Ruiz Perez, Jaime, Salinero Acevedo, José Ramón, Sánchez Apresa, Manuel, Sanchez Calavera, María Antonia, Sánchez Garcia, Fernando, Sánchez Gutiérrez, Miguel Ángel, Sánchez Ibáñez, Antonio, Sánchez López, Eugenio, Sánchez Loureiro, Manuel, Sanchez Lozano, Ana, Sánchez Romero, Gregorio, Sánchez Ruano, Fernando, Sánchez Ruiz, Gabriela, Sánchez Sanchez, Froilán, Santiago Ayarza, Asier, Santos Bermejo, Juan Antonio, Sanz de Miguel, Elena, Sanz Sanz, Marta, Sanz Velasco, Carmelina, Sauco Colón, Inmaculada, Sedano García, José Ignacio, Segovia Castro, Luis, Senan Sanz, María Rosa, Serra Cabot, Pere, Serra Gallego, Marta, Serrano Tomás, Daniel, Sesma Aisa, Francisco Tomás, Seuba Garcés, Jordi, Soler David, Vicente, Soria Mesa, Jose Antonio, Sosa Álvarez, César, Suárez Pérez, María, Tafalla Martín, Antonio, Tamayo Ferriol, Thaimi, Tamayo Marín, José Luis, Thalamas Atienza, Juan Aitor, Toledo Muñoz, Ana María, Tomás-Rodo Massaneda, Lluis Miquel, Torres de Castro, Milko, Torres Martínez, Francisco Javier, Tovar Álvarez, Enrique, Ugarte Goñi, Ainhoa, Valle González, Irene, Vasco Mahillo, Sonia, Enrique José, Vázquez Seijas, Vericat Roure, Antonio, Villalba Parrado, Arelis, Villanueva Rebollo, Jose María, Villar Valgañon, Ricardo, Villena Masegosa, Vicente, Viñals Gigena, Montserrat, Viñas Cabrera, Lydia, Zarco Pinteño, David, Roman-Rodriguez, M., Molina-Paris, J., and Fernandez-Sanchez, A.

Published
2021
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15. Accouchement normal : accompagnement de la physiologie et interventions médicales. Recommandations de la Haute Autorité de Santé (HAS) avec la collaboration du Collège National des Gynécologues Obstétriciens Français (CNGOF) et du Collège National des Sages-Femmes de France (CNSF) – Texte des recommandations (texte court)

Author

Petitprez, K., Guillaume, S., Mattuizzi, A., Arnal, M., Artzner, F., Bernard, C., Bonnin, M., Bouvet, L., Caron, F.-M., Chevalier, I., Daussy-Urvoy, C., Ducloy-Bouthorsc, A.-S., Garnier, J.-M., Keita-Meyer, H., Lavillonnière, J., Lejeune-Sadaa, V., Leray, C., Morandeau, A., Morau, E., Nadjafizade, M., Pizzagalli, F., Schantz, C., Schmitz, T., Shojai, R., Hédon, B., and Sentilhes, L.

Published
2020
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17. EE71 Cost-Effectiveness Analysis of Using Foundationone Liquid CDx in Patients With Advanced Non-Small Cell Lung Cancer in Whom Tissue-Based Testing Is Not Feasible

Author

Isla, D., primary, Alvarez-Alvarez, R., additional, Arnal, M., additional, Arriola, E., additional, Azkarate, A., additional, Azkona, E., additional, García-Campelo, R., additional, Garrido, P., additional, Nadal, E., additional, Ortega, A.L., additional, Carcedo, D., additional, Villacampa, A., additional, Lozano, V., additional, Córcoles, F., additional, Lavara, J., additional, and Bernabé, R., additional

Published
2023
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18. Observations towards early-type stars in the ESO-POP survey: II -- searches for intermediate and high velocity clouds

Author

Smoker, J. V., Hunter, I., Kalberla, P. M. W., Keenan, F. P., Morras, R., Hanuschik, R., Thompson, H. M. A., Silva, D., Bajaja, E., Poppel, W. G. L., and Arnal, M.

Subjects
Astrophysics
Abstract

We present CaII K and TiII optical spectra of early-type stars taken mainly from the UVES Paranal Observatory Project, plus HI 21-cm spectra from the Vila-Elisa and Leiden-Dwingeloo surveys, which are employed to obtain distances to intermediate and high velocity clouds. HI emission at a velocity of -117 km/s towards the sightline HD 30677 with NHI=1.7x10^19 cm-2 has no corresponding CaII K absorption, which has a signal-to-noise (S/N) ratio of 610. The star has a spectroscopically determined distance of 2.7-kpc, and hence sets this as a firm lower distance limit towards Anti-Centre cloud ACII. Towards another sightline (HD 46185), HI at +122 km/s and NHI=1.2x10^19 cm-2 is seen. The CaII K spectrum has a S/N = 780, although no absorption is observed at the cloud velocity. This similarly places a firm lower distance limit of 2.9-kpc towards this parcel of gas that may be an intermediate velocity cloud. The lack of intermediate velocity (IV) CaII K absorption towards HD 196426 at a S/N = 500 reinforces a lower distance limit of 700-pc towards this part of Complex gp, where NHI is 1.1x10^19 cm-2 and velocity is +78 km/s. Additionally, no IV CaII K is seen in absorption in the spectrum of HD 19445, which is strong in HI with NHI=8x10^19 cm-2 at -42 km/s, placing a firm although uninteresting lower distance limit of 39-pc to this part of IV South. Finally, no HV CaII K absorption is seen towards HD 115363 at a S/N = 410, placing a lower distance of 3.2-kpc towards the HVC gas at velocity of +224 km/s and NHI=5.2x10^19 cm-2. This gas is in the same region of the sky as complex WE (Wakker 2001), but at higher velocities. The non-detection of CaII K absorption sets a lower distance of 3.2-kpc towards the HVC, which is unsurprising if this feature is indeed related to the Magellanic System., Comment: Accepted by MNRAS

Published
2007
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20. Respiratory disorders of farmed rabbits: occurrence and risk factors

Author

Rosell, Joan M., primary, De la Fuente, L. Fernando, additional, Badiola, J. Ignacio, additional, Pérez de Rozas, Ana, additional, Fernández de Luco, Daniel, additional, Arnal, M. Cruz, additional, Casal, Jordi, additional, Fernández, Xosé M., additional, and Pinto de Carvalho, André, additional

Published
2023
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26. Past, present and future of chamois science

Author

Corlatti, L., primary, Iacolina, L., additional, Safner, T., additional, Apollonio, M., additional, Buzan, E., additional, Ferretti, F., additional, Hammer, S. E., additional, Herrero, J., additional, Rossi, L., additional, Serrano, E., additional, Arnal, M. C., additional, Brivio, F., additional, Chirichella, R., additional, Cotza, A., additional, Crestanello, B., additional, Espunyes, J., additional, Fernández de Luco, D., additional, Friedrich, S., additional, Gačić, D., additional, Grassi, L., additional, Grignolio, S., additional, Hauffe, H. C., additional, Kavčić, K., additional, Kinser, A., additional, Lioce, F., additional, Malagnino, A., additional, Miller, C., additional, Peters, W., additional, Pokorny, B., additional, Reiner, R., additional, Rezić, A., additional, Stipoljev, S., additional, Tešija, T., additional, Yankov, Y., additional, Zwijacz‐Kozica, T., additional, and Šprem, N., additional

Published
2022
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27. Past, present and future of chamois science

Author

Corlatti, L., Iacolina, L., Safner, T., Apollonio, M., Buzan, E., Ferretti, F., Hammer, S. E., Herrero, J., Rossi, L., Serrano, E., Arnal, M. C., Brivio, F., Chirichella, R., Cotza, A., Crestanello, B., Espunyes, J., Fernández de Luco, D., Friedrich, S., Gačić, D., Grassi, L., Grignolio, S., Hauffe, H. C., Kavčić, K., Kinser, A., Lioce, F., Malagnino, A., Miller, C., Peters, W., Pokorny, B., Reiner, R., Rezić, A., Stipoljev, S., Tešija, T., Yankov, Y., and Šprem, T. Zwijacz-Kozica and N.

Published
2022

29. Prediction of Three-Dimensional Unsteady Lid-Driven Cavity Flow

Author

Arnal, M., Lauer, O., Lilek, Ž., Perić, M., Hirschel, Ernst Heinrich, editor, Fujii, Kozo, editor, van Leer, Bram, editor, Morton, Keith William, editor, Pandolfi, Maurizio, editor, Rizzi, Arthur, editor, Roux, Bernard, editor, Deville, Michel, editor, Lê, Thien-Hiep, editor, and Morchoisne, Yves, editor

Published
1992
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35. NGS-based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment

Author

Sánchez-Herrero E, Serna-Blasco R, Ivanchuk V, García-Campelo R, Dómine Gómez M, Sánchez JM, Massutí B, Reguart N, Camps C, Sanz-Moreno S, Calabuig-Fariñas S, Jantus-Lewintre E, Arnal M, Fernández-Orth D, Calvo V, González-Rumayor V, Provencio M, and Romero A

Subjects
ALK-TKI, liquid biopsy, hemic and lymphatic diseases, NGS, EML4-ALK, NSCLC, neoplasms
Abstract

Despite impressive and durable responses, nonsmall cell lung cancer (NSCLC) patients treated with anaplastic lymphoma kinase (ALK) inhibitors (ALK-Is) ultimately progress due to development of resistance. Here, we have evaluated the clinical utility of circulating tumor DNA (ctDNA) profiling by next-generation sequencing (NGS) upon disease progression. We collected 26 plasma and two cerebrospinal fluid samples from 24 advanced ALK-positive NSCLC patients at disease progression to an ALK-I. These samples were analyzed by NGS and digital PCR. A tool to retrieve variants at the ALK locus was developed (VALK tool). We identified at least one resistance mutation in the ALK locus in ten (38.5%) plasma samples; the G1269A and G1202R mutations were the most prevalent among patients progressing to first- and second-generation ALK-Is, respectively. Overall, 61 somatic mutations were detected in 14 genes: TP53, ALK, PIK3CA, SMAD4, MAP2K1 (MEK1), FGFR2, FGFR3, BRAF, EGFR, IDH2, MYC, MET, CCND3, and CCND1. Specifically, a deletion in exon 19 in EGFR, a non-V600 BRAF mutation (G466V), and the F129L mutation in MAP2K1 were identified in four patients who showed no objective survival benefit from ALK-Is. Potential ALK-I-resistance mutations were also found in PIK3CA and IDH2. Finally, a c-MYC gain, along with a loss of CCND1 and FGFR3, was detected in a patient progressing on a first-line treatment with crizotinib. We conclude that NGS analysis of liquid biopsies upon disease progression identified different putative ALK-I-resistance mutations in most cases and could be a valuable approach for therapy decision making.

Published
2021

37. Seroepidemiology of Toxoplasma gondii in wild ruminants in Spain

Author

Balseiro Morales, Ana María [0000-0002-5121-7264], Jiménez Ruiz, S., Castro Scholten, S., Cano Terriza, D., Almeria, S., Risalde, M. A., Vicente, J., Acevedo, P., Arnal, M. C., Balseiro, Ana, Gómez Guillamón, F., Escribano, F., Puig-Ribas, M., Dubey, Jitender P., García Bocanegra, I., Balseiro Morales, Ana María [0000-0002-5121-7264], Jiménez Ruiz, S., Castro Scholten, S., Cano Terriza, D., Almeria, S., Risalde, M. A., Vicente, J., Acevedo, P., Arnal, M. C., Balseiro, Ana, Gómez Guillamón, F., Escribano, F., Puig-Ribas, M., Dubey, Jitender P., and García Bocanegra, I.

Published
2021

38. Seroepidemiology of Toxoplasma gondii in wild ruminants in Spain

Author

Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), European Commission, Balseiro Morales, Ana María [0000-0002-5121-7264], Castro-Sholten, S., Cano-Terriza, David, Jiménez-Ruiz, S., Almería, Sonia, Risalde, M. A., Vicente, J., Acevedo, Pelayo, Arnal, M. C., Balseiro, Ana, Gómez-Guillamón, Félix, Escribano, F., Puig-Ribas, M., Dubey, Jitender P., García-Bocanegra, I., Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), European Commission, Balseiro Morales, Ana María [0000-0002-5121-7264], Castro-Sholten, S., Cano-Terriza, David, Jiménez-Ruiz, S., Almería, Sonia, Risalde, M. A., Vicente, J., Acevedo, Pelayo, Arnal, M. C., Balseiro, Ana, Gómez-Guillamón, Félix, Escribano, F., Puig-Ribas, M., Dubey, Jitender P., and García-Bocanegra, I.

Published
2021

40. El Curso Mamíferos del Pirineo, 2012-2018

Author

Alcántara, Manuel, primary, Arnal, M. Cruz, additional, Azón, Ricardo, additional, Fillat, Federico, additional, García-González, Ricardo, additional, Herrero Cortés, Juan, additional, Jimeno, Pilar, additional, MIranda, Javier, additional, Ortiz, Quintina, additional, Oto, Antonio, additional, Pérez, Enrique, additional, Rabal-Garcés, Raquel, additional, Salamendi, Egoitz, additional, Sanz, Benjamín, additional, and Sauqué, Sauqué, additional

Published
2021
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41. Archaea, specific genetic traits, and development of improved bacterial live biotherapeutic products : another face of next-generation probiotics

Author

Fadhlaoui, K., Arnal, M. E., Martineau, M., Camponova, P., Ollivier, Bernard, O'Toole, P. W., and Brugere, J. F.

Subjects
hemic and lymphatic diseases, LBP, Trimethylamine oxide TMAO, Archaebiotics, Trimethylamine TMA, Trimethylaminuria TMAU, Live biotherapeutic products, Cardiovascular disease CVD, urologic and male genital diseases, neoplasms, digestive system, female genital diseases and pregnancy complications
Abstract

Trimethylamine (TMA) and its oxide TMAO are important biomolecules involved in disease-associated processes in humans (e.g., trimethylaminuria and cardiovascular diseases). TMAO in plasma (pTMAO) stems from intestinal TMA, which is formed from various components of the diet in a complex interplay between diet, gut microbiota, and the human host. Most approaches to prevent the occurrence of such deleterious molecules focus on actions to interfere with gut microbiota metabolism to limit the synthesis of TMA. Some human gut archaea however use TMA as terminal electron acceptor for producing methane, thus indicating that intestinal TMA does not accumulate in some human subjects. Therefore, a rational alternative approach is to eliminate neo-synthesized intestinal TMA. This can be achieved through bioremediation of TMA by these peculiar methanogenic archaea, either by stimulating or providing them, leading to a novel kind of next-generation probiotics referred to as archaebiotics. Finally, specific components which are involved in this archaeal metabolism could also be used as intestinal TMA sequesters, facilitating TMA excretion along with stool. Referring to a standard pharmacological approach, these TMA traps could be synthesized ex vivo and then delivered into the human gut. Another approach is the engineering of known probiotic strain in order to metabolize TMA, i.e., live engineered biotherapeutic products. These alternatives would require, however, to take into account the necessity of synthesizing the 22nd amino acid pyrrolysine, i.e., some specificities of the genetics of TMA-consuming archaea. Here, we present an overview of these different strategies and recent advances in the field that will sustain such biotechnological developments.

Published
2020

43. P84.14 Identification of Mechanisms of Resistance to ALK Inhibitors. Next-Generation Sequencing-Based Liquid Biopsy Profiling.

Author

Sánchez-Herrero, E., primary, Serna-Blasco, R., additional, Ivanchuk, V., additional, Garcia Campelo, R., additional, Dómine Gómez, M., additional, Sanchez, J.M., additional, Massuti, B., additional, Reguart, N., additional, Camps, C., additional, Sanz-Moreno, S., additional, Fariñas, S., additional, Jantus-Lewintre, E., additional, Arnal, M., additional, Fernández-Orth, D., additional, González-Rumayor, V., additional, Calvo, V., additional, Provencio, M., additional, and Romero, A., additional

Published
2021
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