1. Bioactive Sesquiterpene Aryl Esters from the Culture Broth of Armillaria sp
- Author
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Jae-Hoon Choi, Atsushi Sekiya, Hirofumi Hirai, Hajime Kobori, Hirokazu Kawagishi, and Tomohiro Suzuki
- Subjects
Pharmaceutical Science ,Biology ,Sesquiterpene ,Analytical Chemistry ,chemistry.chemical_compound ,Drug Discovery ,Armillarinin ,Botany ,Nuclear Magnetic Resonance, Biomolecular ,Armillaridin ,Mycelium ,Flammulina ,Pharmacology ,Molecular Structure ,Aryl ,Organic Chemistry ,Armillaria sp ,Esters ,Armillaria ,Lettuce ,biology.organism_classification ,Coprinopsis cinerea ,Complementary and alternative medicine ,chemistry ,Molecular Medicine ,Sesquiterpenes - Abstract
Two new compounds, 10-dehydroxymelleolide D (1) and 13-hydroxymelleolide K (2), along with seven known compounds, 5'-O-methylmelledonal (3), melleolide D (4), 13-hydroxydihydromelleolide (5), melleolide (6), armillarinin (7), armillaridin (8), and armillarikin (9), were isolated from the culture broth of Armillaria sp. Their structures were determined by spectroscopic data analysis. All the compounds inhibited plant growth of lettuce. Melleolide (6) and armillarikin (9) inhibited mycelial growth of Coprinopsis cinerea and/or Flammulina velutipes.
- Published
- 2014