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Integrated Science Process Skills online learning cannot be taught optimally so learning media are needed that can teach integrated, interactive, and practical SPS. One such media is an e-module. This study aimed to determine the feasibility and effectiveness of Guided Inquiry-Based e-module, or Mosiry, in improving Integrated SPS of Class XI students in the Immune System subject. This research is a developmental research, using the 4D development design stages: 1) Defining; 2) Designing; 3) Developing; and 4) Disseminating. The sample was selected using a purposive sampling method. Data was collected by using observation, interviews, questionnaires, and pretest/post-test; and data was analysed based on media feasibility, and effectiveness analysis. The results of this study were that the Mosiry e-module is suitable for use as a learning medium for the Immune System and could improve students' SPS in the moderate category.

Given a plane graph $G=(V,E)$. A zonal labeling of graph $G$ is defined as an assignment of the two nonzero elements of the ring $\mathbb{Z}_3$, which are $1$ and $2$, to the vertices of $G$ such that the sum of the labels of the vertices on the border of each region of the graph is $0\in\mathbb{Z}_3$. A graph $G$ that possess such a labeling is termed as zonal graph. This paper will characterize edge comb product graphs that are zonal. The results show that $P_m\trianglerighteq_eC_n$, $C_n\trianglerighteq_e C_r$, $S_p\trianglerighteq_e C_n$, and $S_p\trianglerighteq_e F_t$ are zonal in some cases, but not in others.

BACKGROUND AND OBJECTIVES: A major function of mangroves is carbon sequestration in sediment. This study aimed to determine differences in carbon content in sediments in various types of mangroves and environmental parameters.METHODS: This study was carried out in Pesawaran as a natural mangrove and in South Lampung as rehabilitated mangrove in Indonesia. Purposive sampling method was used by considering the types of mangroves at the locations. Sediment sampling was taken using a polyvinyl chloride pipe with a diameter of 47.46 milimeters and a height of 30 centimeters. The sediment parameters measured were bulk density, carbon stock, and sequestration. Environmental parameters measured included sediment texture, potential of hydrogen, temperature, salinity, and total dissolved solids. A statistical analysis was conducted using the principal component analysis to determine the relationship between the organic carbon stock and the environmental parameters.FINDINGS: The study results showed that natural mangroves (Pesawaran) had a higher organic carbon value at 2.2 ± 0.32 percent than rehabilitated mangroves (South Lampung) at 0.9 ± 0.25 percent. The principal component analysis results revealed that organic carbon, carbon dioxide equivalent, carbon stock, and carbon sequestration had positive correlation characteristics influenced by salinity, silt, and clay, while negative correlation characteristics were affected by temperature, total dissolved solids, and sand. The distribution of sediment texture tended to show more silt in rehabilitated mangroves, while natural mangroves tended to have the same composition between sand and silt. The potential of hydrogen conditions in natural and rehabilitated mangroves showed no significant differences in values. The salinity in Pesawaran, which was classified as a natural mangrove, was higher due to the influence of the tides and was directly facing the shoreline. Meanwhile, in South Lampung, which was categorized as a rehabilitated mangrove, the salinity was lower due to the long dry season and the canals being unable to support the water entering the mangroves.CONCLUSION: The organic carbon content at the research locations was influenced by the older age of the Rhizophora stylosa compared to that of the Rhizophora mucronata and Ceriop tagal types of mangroves. The carbon sequestration rate values showed 1.65–3.14 for natural mangroves and 0.29–1.25 for rehabilitated mangroves, thus establishing that the rate is higher (2–3 times) in natural mangroves than in rehabilitated mangroves.

BACKGROUND AND OBJECTIVES: Improving welfare requires continuous and various efforts, including enhancing social capital and local institutions for the preservation of mangrove forests. Reinforcing local social and institutional capital to enhance mangrove ecosystems is crucial for understanding the intricate social systems necessary to conserve, manage, and restore mangrove ecosystem services. The purpose of this study is to determine the relationship between social capital and social institutions with the sustainability of mangrove rehabilitation in the Teluk Pandan and Padang Cermin districts of Lampung, Indonesia, in 2023.METHODS: This study analyzes the role of local social and institutional capital in the welfare of communities residing around mangrove forests in the Way Ratai district of Pesawaran Regency. This study employs a survey research approach, drawing samples from the population, and utilizes both quantitative and qualitative data analysis. A sample of 300 respondents was selected based on the guidelines for Structural Equation Model analysis. The study was carried out in two sub-districts of Pesawaran Regency. The districts were deliberately chosen due to the fact that they are designated mangrove forest rehabilitation areas. Data collection took place from July to December 2023. Data analysis involved tabulation techniques and Structural Equation Model analysis using Linear Structural Relations.FINDINGS: The findings suggest that social institutions, such as customary practices, sanctions, and conflict, have a negative impact on mangrove rehabilitation and welfare. Increasing the social capital of communities surrounding mangrove forests has a significant influence on mangrove rehabilitation and welfare, including the fulfillment of basic needs like shelter, food, access to healthcare, and education. Community leaders oversee activities, encourage community involvement in mangrove rehabilitation, and ensure the smooth running of government programs.CONCLUSION: Social capital can be enhanced through group meetings, social gatherings, initiatives to raise awareness about tourism, and mangrove conservation groups. The goal of empowerment is to create self-sufficient and socially empowered communities capable of meeting their physical, economic, and social needs. This fosters self-confidence and allows them to voice their aspirations, secure their livelihoods, engage in social endeavors, and face life independently. Social capital influences community participation in mangrove rehabilitation.

Electrospinning is one of the techniques used to fabricate nanofibers. The syringe pump is one of the main parts of electrospinning, responsible for injecting the solution into the chamber with high precision. The syringe pump has a simple operating system, but it has a high price on the market. Its high price has been one of the obstacles for research groups in the fabrication of nanofibers. Hence, this research aimed to solve the problem of expensive syringe pumps by developing a low-cost syringe pump using affordable components. This research utilized methods from a literature study of syringe pump design, including the manufacturing and assembly of both hardware and software components. It also involved testing the calibration, optimization, and performance of the syringe pumps. An analysis of each stage was carried out until a conclusion was obtained. This syringe pump built in this research used a NEMA 17 stepper motor and TB6600 motor driver to control the flow rate. The total cost to develop this low-cost syringe pump was IDR632,300. Test and calibration were measured at a flow rate ranging from 1 mL/h to 5 mL/h using distilled water, resulting in an accuracy value of 96.7% and a precision value of 95.0%. Further research should utilize gear wheels to reduce the load of the motor stepper so as to prevent prolonged heated conditions. The results of this research can also be used as insight for researchers to develop another low-cost tool in other research fields.

Mohammad Parezal Lastialno,1 Muhammad Hasan Bashari,2 Eko Fuji Ariyanto2,3 1Program of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, 40161, Indonesia; 2Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 3Study Center for Medical Genetics, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, 40161, IndonesiaCorrespondence: Eko Fuji Ariyanto, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km.21, Sumedang, West Java, 45363, Indonesia, Email fuji@unpad.ac.idAbstract: Obesity is a condition in which there is an accumulation of excess body fat leading to a weight far above the normal range that poses significant health risks. According to WHO, 8 billion people in the world were obese in 2022. Consequently, obesity has become a pandemic with negative impacts on both global health and economies. Obesity is influenced by various factors including environmental influences, lifestyle choices, gut microbiota, genetic factors, and epigenetic mechanisms such as DNA methylation. DNA methylation can affect an individual’s phenotype and condition without altering their DNA sequence. It is the most extensively studied epigenetic alteration and it plays an important part in controlling gene activity associated with obesity. Numerous studies have indicated that DNA methylation is implicated in obesity, thus this review aims to elaborate the roles of DNA methylation to inform the development of preventive measures for obesity.Keywords: DNA methylation, epigenetics, obesity, prevention

Power plant projects are crucial to providing andining a reliable power system. Power plant projects, like other construction projects, often experience a problem of delayed completion of work known as time overrun, which can result in financial losses and project failure to be completed on time. Time overrun is overtime that exceeds the completion date specified in the contract or the project submission date agreed by both parties. Engineering, procurement, construction, and commissioning are all parts of the power plant construction project. In completing the project, it is essential to understand why the power plant construction project is delayed and how to properly mitigate the risk. This research is quantitative research, which means using a questionnaire. The aim of this study is to find out what caused the time overrun of the power plant project at the Timorese PLTU. Partial Least Square Structural Equation Modeling (PLS-SEM) is used to process data from questionnaire results. The results of the research showed that there were seven research hypotheses, with two accepted and five rejected. The external factors, and the owner-related factors are the time overrun factors based on the accepted hypothesis. Based on the cause of the time overrun, some mitigation measures can be recommended to management including a memorandum of understanding (MoU) scheme with stakeholders related to existing permits, a scheme related to contractual and technical procedures when unforeseen conditions occur and ensuring the quality of the results of the soil investigation.

The development of Smart Contract in this regard can be attributed to the stability of Indonesian law, where methods for executing contracts have become increasingly sophisticated. With the rapid growth of technological developments that use Smart Contracts and the urgency of the extent to which the current laws in Indonesia can support their development, the question arises of how Smart Contract work? When does the meeting of minds occur in a Smart Contract? And, how is the fulfillment of the principle of consensualisme in Smart Contract viewed from the perspective of Article 1320 of the Civil Code? The research method in this study was carried out using a qualitative normative method .The results of this study show, Smart Contract works by running without a third party and written on the Blockchain. Second, there is a meeting of minds in the Smart Contract, where both parties who intend to bind themselves in the Smart Contract send their cryptographic encryption to commit to each other in the Smart Contract, as proof that both have mutually agreed. Third, the principle of consensualism in Smart Contract from the perspective of Article 1320 of the Civil Code shows that agreement is an essential foundation for the validity of an agreement, ensuring that each party involved has agreed to the existing provisions.

Wilayah Kemiling yang terletak di Kota Bandar Lampung sering kali mengalami gempa lokal dengan magnitudo kecil. Gempa ini terjadi secara berulang dan dirasakan di daerah Kemiling dan sekitarnya. Hal tersebut dapat menimbulkan kekhawatiran bagi warga dan dapat merusak bangunan. Fokus utama pada studi ini adalah untuk memahami bagaimana karakteristik tanah dan indeks kerentanan seismik di daerah tersebut. Untuk meminimalisir dampak kerusakan akibat gempa, perlu dilakukan mikrozonasi pada wilayah rawan gempa. Parameter mikrozonasi yang digunakan untuk mengetahui karakteristik tanah antara lain amplifikasi (A0), frekuensi natural (f0), indeks kerentanan seismik (Kg), periode dominan (T0), dan kecepatan gelombang geser hingga kedalaman 30 meter (VS30). Sebanyak 65 titik pengukuran mikrotremor telah diukur di Kecamatan Kemiling dan sekitarnya meliputi kota Bandar Lampung, Kecamatan Gedong Tataan, dan Kecamatan Natar. Pada penelitian ini digunakan analisis metode Horizontal to Vertical Spectral Ratio (HVSR) dan didapatkan bahwa frekuensi natural berkisar antara 0,5-31,47 Hz, periode dominan 0,03-2,0 sekon, amplifikasi 0,76-7,67 kali penguatan, indeks kerentanan seismik 0,05-76,31, dan VS30 49,61-777,80 m/s. Hasil penelitian menunjukkan bahwa wilayah barat daya hingga utara Kemiling memiliki risiko kerentanan yang lebih tinggi dibandingkan wilayah lainnya dengan tipe tanah berupa tanah lunak. Oleh karena itu, diperlukan tindakan mitigasi yang tepat, termasuk pengembangan rencana mitigasi risiko, pemantauan lanjutan, dan keterlibatan aktif masyarakat dalam perencanaan darurat.

The Asian tapir Tapirus indicus is the only tapir species in Southeast Asia. It is declining across its range and is categorized as Endangered on the IUCN Red List. The forests of Sumatra are critical to Asian tapir conservation as they contain some of the last remaining populations of the species, yet conservation efforts are hindered by a lack of information on habitat suitability. We collated camera-trap data from nine landscapes across 69,500 km2 of Sumatran rainforest to help predict suitable habitat for Asian tapirs on the island. Predictions from Bayesian occupancy models demonstrated that tapir occupancy was greatest in forests below 600 m elevation and exclusively in forests with high aboveground biomass. Forests around the Barisan Mountains on the west of Sumatra provide the most suitable habitat for the species. Only 36% of the most critical habitat (i.e. 80th percentile of predicted occupancy values, or above) for tapirs is formally protected for conservation, with much of the remainder found in forests allocated to watershed protection (35%) or logging (23%). We highlight several key areas in Sumatra where tapir conservation could be bolstered, such as by leveraging existing conservation efforts for other charismatic flagships species on the island.

The government formed a draft law on job creation which aims to facilitate the business climate in Indonesia. This bill is included in the 2020 Prolegnas priority list and is expected to increase Indonesia's ease of doing business ranking in the world, especially related to indicators of starting a business which lags behind neighboring countries and ranks fifth at the ASEAN level. For this reason, the Government has created a breakthrough so that everyone can easily start a business, especially for Micro and Small Enterprises (UMK). A number of clusters of Draft Laws have been prepared and one of these sub-clusters is related to the formation of business entities. In order to realize the ease of doing business, there is a need to form a new type of business entity, especially for Micro and Small Enterprises in the form of a Limited Liability Company (PT) which was established by one person. Individual Limited Liability Companies are expected to provide convenience for Micro and Small Business actors in forming companies with minimum requirements and capital. By using the normative juridical method, this article discusses the concept of an individual limited liability company by comparing the arrangements with other countries so that it can be a lesson for Indonesia if it wants to make this happen. From the results of the study, appropriate and comprehensive arrangements are needed in order to realize a Limited Liability Company for Micro and Small Businesses in order to support the ease of doing business in Indonesia.

This research focused on the evaluation of raw broiler chicken meat texture and pathogenic antibacterial effect under the treatment of grade 2 coconut-shell liquid smoke (CSLS) as a food preservative. Compound identification of grade 2 CSLS was conducted using the GC-MS method. The main chemical compounds of CSLS were polyunsaturated fatty acid derivates, fatty acid and phenol. The evaluation of texture was conducted on raw broiler chicken meat under the treatment of grade 2 CSLS during storage at 25 ℃ for 7 days. The effect of antibacterial activity of grade 2 CSLS with different concentration (i.e., 5%, 25%, 50%, and 75%) were tested using Gram-positive bacteria on several pathogenic bacteria such as L. monocytogenes, S. aureus, P. Aeruginosa, and E. coli. The results indicated that grade 2 CSLS influenced the inhibited zone of L. monocytogenes, S. aureus, P. Aeruginosa, and E. coli respectively with linear correlation. The optimal concentration of grade 2 CSLS resulted in a concentration of 50%, which was the most optimal against L. monocytogenes, S. aureus, P. Aeruginosa, and E. coli as pathogenic bacteria strains.

الملخص: أهداف البحث: في مجال الخدمات الصحية، يعد التمريض عن بعد نظاما معاصرا لتكنولوجيا المعلومات والاتصالات يتيح توفير الرعاية والخدمات التمريضية للمناطق النائية. لقد ثبت أن التمريض عن بعد يمكن أن يساعد في تحسين الصحة النفسية للمرضى المزمنين بشكل عام. ومع ذلك، لم يتم إجراء أي تقييم لتأثير التمريض عن بعد على مرضى قصور القلب. وللتأكد من كيفية تأثير علاجات التمريض عن بعد على نوعية حياة مرضى قصور القلب. طريقة البحث: كانت معايير الاشتمال هي المقالات من 2015 إلى 2023 باللغة الإنجليزية. المشاركون الذين يعانون من قصور القلب مع تدخل التمريض عن بعد، كانت النتائج في شكل نوعية الحياة، وشملت البحوث تجربة منضبطة معشاة. معايير الاستبعاد هي الاضطرابات النفسية، ومراجعات الأدبيات، والمراجعات المنهجية، والمراجعات الشاملة. تم إجراء المراجعة في خمس قواعد بيانات: ''بابميد''، ''سكوبس''، ''ويللي''، ''بروكويست''، ''اميرلاند انسايت''. تم إجراء التقييم النقدي باستخدام قائمة التقييم النقدي الخاصة بمعهد جوانا بريجز. النتائج: استوفت إحدى عشرة تجربة منضبطة معشاة (2032 مريضا) معايير الاشتمال، وأظهرت هذه المراجعة أنه كان هناك تأثير كبير على نوعية الحياة بعد استخدام التدخل للتمريض عن بعد مع عدم تجانس عالي بنسبة 98٪. الاستنتاجات: يمكن لتدخلات التمريض عن بعد أن تحسن نوعية حياة مرضى قصور القلب. لذلك يمكن تطبيق التمريض عن بعد في المستشفيات في تقديم الرعاية التمريضية لتوفير التعليم ومراقبة نوعية حياة مرضى قصور القلب عن بعد. Abstract: Introduction: In the field of health services, telenursing is a contemporary information and communication technology system that enables the provision of nursing care and services to remote areas. Telenursing can increase psychological general well-being in patients with chronic conditions. Nevertheless, the effects of telenursing on patients with heart failure have not been examined. Objective: This study was aimed at ascertaining how telenursing treatments affect quality of life in patients with heart failure. Method: The inclusion criteria were articles from 2015 to 2023 in English, reporting quality of life outcomes for participants with heart failure in randomized controlled trials of telenursing interventions. The exclusion criteria were studies of psychiatric disorders, literature reviews, systematic reviews, and umbrella reviews. The systematic review was registered with PROSPERO registration number CRD42023484361. The review was conducted with five databases: PubMed, Scopus, Willey, Proquest, and Emerald Insight. Critical appraisal was conducted with the Joanna Briggs Institute's Critical Appraisal Checklist. The data were synthesized with Review Manager version 5.4. Results: Eleven randomized controlled trials (2032 patients) met the inclusion criteria. A significant effect on quality of life was observed after telenursing intervention. The heterogeneity was high, at 98% (SMD = 1.05; 95% CI [0.12, 1.98]; ρ = 0.03). Conclusion: Telenursing interventions can improve quality of life among patients with heart failure and therefore may be applied in hospitals providing nursing care, to remotely provide education and monitor the quality of life of patients with heart failure.

This study evaluates how place attachment and familiarity influence destination loyalty among beach visitors in Batam. This research was structured based on a quantitative approach to validate the hypotheses that have been suggested. The target population in this research is tourists who visit beaches in Batam. The data collected is then analyzed using statistical analysis techniques such as the t-test. Based on the test, it was found that 50.2% of the influence exerted on the dependent variable came from the independent variable, while the remaining 49.8% resulted from other factors not included in this research model. The conclusions of this research confirm that place attachment and familiarity significantly influence destination loyalty and can be considered critical elements in retaining tourists in the Batam beach destination. Keywords: Place Attachment; Familiarity; Destination Loyalty

This study examines the effect of performance appraisal, work motivation, and discipline on promotion at PT Pertamina Patra Niaga IT Kertapati Palembang. The population in this study were employees who worked at PT Pertamina Patra Niaga IT Kertapati Palembang with a total of 159 employees. Sampling was carried out using the probability sampling method, and then a sample of 62 employees who will be the respondents was generated. The measurement scale used in this study is the Likert scale. This research uses analysis techniques of validity test, reliability test, classic assumpton test, simple regression analysis, multiple linear regression analysis, coefficient of determination (R2), and hypothesis testing which consists of F test (simultaneous) and t-test (partial). The results of this study concluded that partial and simultaneous assessment of work performance, motivation, and work discipline had a significant effect on promotion at PT Pertamina Patra Niaga IT Kertapati Palembang. Keywords: Performance Appraisal; Motivation; Work Discipline; Job Promotion

Currently, the gap between the theory taught in lectures and the practical needs in Indonesian language internationalization projects hinders students' mastery of competencies in studying the Indonesian Language Development course. There is a pressing need to update the Indonesian Language Development curriculum to emphasize practical application, such as language development projects and the use of Indonesian in international contexts. Active student involvement through participatory and collaborative approaches is key to preparing students for the challenges of Indonesian language development in the era of globalization. This study aims to evaluate the Indonesian Language Development course, focusing on the internationalization of the language, and is based on participatory and collaborative learning. The method employed is the Goal-Oriented Evaluation Model, which involves identifying specific needs by analyzing issues in the Indonesian Language Development course. It identifies the objectives of the internationalization program based on clear indicators and proposes actions to improve teaching and learning. Data collection methods include classroom observations, student performance surveys, and interviews, along with a literature review to support an understanding of suitable participatory and collaborative learning methods The findings show that teaching methods incorporating technology, field practice, and interactive activities create positive and meaningful learning experiences. The evaluation, including student participation and collaboration, has yielded favorable results, with most respondents reporting that this learning is enjoyable, beneficial, and memorable. In conclusion, the study concludes that the learning approaches at University A and University B are appropriate and effective.

Metallic catalytic converter (MCC) is one of the technologies widely applied to motorcycle exhausts which aims to improve exhaust emission to be more environmentally friendly. However, even though many studies have been carried out, optimal design has not been achieved when compared to other designs. Through this research, the Taguchi method is proposed as an alternative method to find the optimum parameters of MCC. The Taguchi method was chosen because of its ability to find a robust combination of parameters. There are four MCC parameters used as inputs while each parameter consists of three levels, thus the design used is the L18 Orthogonal Array (OA) which each combination is tested on three types of vehicles, namely moped, automatic, and sports motorcycle. The signal-to-noise ratio (S/N) was adopted as one of the quality indicators of each combination. The optimization results showed that the best MCC design to reduce CO emissions is STD PGM. However, the optimum CO design can be used as an alternative because the difference in the S/N ratio is only -0.372. Meanwhile, the optimum CO design has another advantage over the STD PGM, namely the S/N value of the power ratio which tends to be higher with a difference of 5.037 compared to the STD PGM. Then, the best MCC design capable of increasing power is the optimum power design. The optimum power design has a superior S/N ratio with a difference of 5.404. In terms of emission, the optimum power design tends to be lower by a difference of -1.875 compared to the STD PGM.

Prey depletion poses a threat to large carnivores worldwide. The Javan leopard (Panthera pardus melas), the last remaining apex predator on the Indonesian island of Java, is facing numerous threats from human activities including poaching, habitat loss and prey depletion. Despite the fact that the Javan leopard is an adaptable and opportunistic predator capable of surviving in various environments, our understanding of its prey and predator-prey interactions is still limited, which is crucial for their conservation. Using camera trap data collected from four national parks (i.e., Ujung Kulon, Gunung Gede Pangrango, Meru Betiri, Alas Purwo) that represent four distinct terrestrial ecoregions across the island of Java, we investigated the species richness, relative abundance, and spatial-temporal overlap in activity patterns between the Javan leopard and other animals that coexist in the same location. Our analysis of 7461 independent photos, covering 12,983 camera trap days, revealed that areas with the presence of Javan leopards exhibited higher species richness and abundance compared to those without the presence of Javan leopards. In addition, we found that the activities of banteng (Bos javanicus), barking deer (Muntiacus muntjak), Javan deer (Rusa timorensis), Javan mousedeer (Tragulus javanicus), wild boar (Sus scrofa), junglefowl (Gallus spp.), spangled ebony langur (Trachypithecus auratus), Javan rhino (Rhinoceros sondaicus), long-tailed macaque (Macaca fascicularis) and dhole (Cuon alpinus) were highly overlapping with those of Javan leopards in space and time, suggesting that these species are potential candidate prey for Javan leopards. To our knowledge, this is the first comprehensive investigation of potential prey for the Javan leopard that utilizes camera traps from all four types of terrestrial ecoregions on Java Island. The findings of this study may serve as essential information for the conservation of this critically endangered species.

The success of establishing the Indonesian growing fast hybrid carp, namely “Permata”, on a controlled environmental test must be followed up with a large-scale test. This study aims to evaluate the phenotypic performance of the Permata hybrid carp in multi-locations with different cultivation systems. The test sites consisted of floating net cages, running-water ponds, semi-concrete ponds, earthen ponds, fully concrete ponds, and static net cages. For 90 days, fish were fed commercial pellets with a 28%–30% protein content. At the end of the test, all fish were harvested and counted. Data on length, weight, survival rate, and harvested biomass were used to analyze the effect of genotype, environment, and their interaction on the phenotypic performance. The growth based on final weight is used to analyze the stability performance in each test location. The results showed that the length and weight of common carp were significantly affected by genotype and the environment, but not by the interaction of both. The genotype, environment, and the interaction of both factors affected common carp’s survival and harvested biomass. Common carp reared in floating net cages generally had the best performance, while carp reared in fully concrete tanks and static net cages had the lowest. The growth stability analysis showed that the common carp in this study were unstable genotypes but have a broad adaptability in term of different environments.

SMAN 1 Durenan has a plan to organize the allocation of classes for new students using a system to achieve practical and efficient student grouping. The reason for implementing this class allocation system is SMAN 1 Durenan aims to create a new system to process student data for class allocation according to specific needs. This research involves the development of a Recommendation System for Clustering to Allocate Classes for New Students using the K-Means method. The system processes data of newly enrolled students at SMAN 1 Durenan based on specific attributes. The results of this student data processing serve as considerations and references for SMAN 1 Durenan to perform class allocation as needed. The analysis in this research utilizes the K-Means method to obtain data clusters that maximize the similarity of characteristics within each group and maximize the differences between the collections created. The developed recommendation system website provides information about the student data clustering results from the K-Means process at SMAN 1 Durenan.

Genetic material is classified as material that is difficult for students to understand because the material is abstract, there are many foreign terms, and there are many complex molecular reactions, so students have difficulty developing critical thinking skills. Therefore, developing a good, suitable, effective, and attractive media is necessary. . This study aims to develop an e-module on the topic of genetic substance, to test the feasibility of the e-module, and to determine the differences in critical thinking skills before and after the implementation of the e-module. This type of research is research and development research with a 4D Thiagarajan model consisting of define, design, development,and disseminate. . This research was conducted without the dissemination stage. The results of the validation of media experts are 81.7% (fair enough) and material experts are 85.5% (very feasible). The results of the trial were limited to 10 students, namely 92.1% (very decent) and 80.4% biology teachers (quite decent). The results of field trials are 90.2% (very feasible). The results of the t-test indicate that there are differences in critical thinking skills before and after the implementation of the e-module. This study implicate that e-modules on the topic of genetic substances are feasible to use and to empower students’s critical thinking skills.

A house is a building that functions as a residence or residence and a means of family development (Law No. 4 of 1992). Every community needs a house as a necessity. With so many people needing a place to live, house construction often occurs. As time goes by, many houses have been built. From the number of houses, they can be classified into several groups, one of the classifications is based on the location where the house was built. The classification of houses based on the location where the house was built is classified into 3, namely houses in rural areas, urban areas and suburban areas. Based on this classification, data on houses being sold on the kaggle.com website was taken. From this data, the characteristics of the houses in the 3 groups can be described. The characteristics chosen are selling price, house area, and number of bedrooms. Using this data, carry out analysis using the MANOVA method. The aim of this research is to determine the influence between house location and selling price, house area and number of rooms

Eko Fuji Ariyanto,1 Ibnu Wijaya,2 Zaky Alif Pradian,2 Agung Putri Mayasari Bhaskara,2 Putri Halleyana Adrikni Rahman,1 Nandina Oktavia1 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, Indonesia; 2Faculty of Medicine, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Eko Fuji Ariyanto, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, Indonesia, Email fuji@unpad.ac.idAbstract: Atherosclerosis is one of the most dominant pathological processes responsible in cardiovascular diseases (CVD) caused by cholesterol accumulation accompanied by inflammation in the arteries which will subsequently lead to further complications, including myocardial infarction and stroke. Although the incidence of atherosclerosis is decreasing in some countries, it is still considered the leading cause of death worldwide. Atherosclerosis is a vascular pathological process that is chronically inflammatory and is characterized by the invasion of inflammatory cells and cytokines. Many reports have unraveled the pivotal roles of epigenetics such as DNA methylation, post-translational histone modifications, and non-coding RNAs (ncRNAs) in atherogenesis, which regulate the expression of numerous genes related to various responsible pathways. Many studies have been conducted to develop new therapeutical approaches based on epigenetic changes for combating atherosclerosis. This review elaborates on recent updates on the development of new atherosclerosis drugs whose mechanism of action is associated with the modulation of DNA methylation, posttranslational histone modifications, and ncRNA-based gene regulation.Keywords: atherosclerosis, DNA methylation, histone modifications, non-coding RNAs, pharmacotherapy

The use of information communication technology for tax reporting has an important role in increasing economic growth and people’s quality of life. This research aims to evaluate the success of information systems and trust in the government on usage and user satisfaction, as well as the impact on tax compliance. The success of information systems consists of three variables, namely information, service, and system quality. This research also involves gender, education, and age as moderating variables. Subsequently, this study investigates whether tax compliance has an impact on a sustainable information society. This research was conducted on micro, small, and medium business taxpayers in Bali Province, Indonesia. Data collection was carried out by distributing survey questionnaires, with 128 taxpayers participating in this research. PLS-SEM was then used to test the hypothesis. This study found that the tax reporting system’s quality has a positive effect on usage and user satisfaction, while trust in the government has no effect. However, this study reveals that gender, education level, and age have no significant effect on the relationship between usage and satisfaction of e-filing users and taxpayer compliance. Furthermore, the results show that usage and user satisfaction have a positive effect on tax compliance, which in turn affects the sustainable information society. This research has implications in terms of the importance of improving the quality of the tax reporting system in Indonesia in realizing a sustainable society.

The critical minerals industries in Indonesia may pose possible environmental and human health risks due to the release of pollutants into soil, water, and air, as well as the use of materials and energy. This study investigates the possible environmental and human health impacts of Indonesia's nickel, gold, copper, tin, and bauxite mining and processing industries. This study utilizes the latest version of the OpenLCA software, version 2.0, in combination with the Ecoinvent 3.8 database. To evaluate potential environmental consequences and health effects on humans, CML-IA Baseline and Environmental Priority Strategies (EPS) are employed in product development. The EPS system was developed utilizing a hierarchical methodology with the objective of furnishing the product developer with data regarding the financial impact of human health impairment resulting from a particular product development. The production of one tonne of gold, nickel, bauxite, tin, and copper results in the emission of 7.34.E+07, 4.61.E+04, 3.10.E+04, 1.02.E+04, 8.01.E+03 kg CO2 eq/t, respectively, contributing to global warming. This production is associated with asthma cases of 7.79.E+01 (gold industry), 2.21.E−03 (copper industry), 1.81.E−03 (tin industry), 9.21.E−04 (nickel industry), and 4.71.E−06 (bauxite industry) Personyears/t. Electricity consumption and the release of carbon dioxide are the main factors contributing to global warming. The primary cause of asthma cases is the utilization of fuel oil and electricity. Power plant chimneys can employ various technologies, such as cyclones, bag filters, and scrubbers, to mitigate the release of polluting gas emissions. The critical mineral industry must prioritize handling and governing of steam power facilities to minimize their negative effects on the environment and human health.

Landslides are natural disasters that most often occur in hilly areas, one of which is in the Manyaran District, and are caused by land use, slope, and rainfall. This study aimed to assess the level of landslides on several slopes and determine the soil characteristics that most determine the level of landslide vulnerability to formulate an appropriate strategy for hilly land management. The sampling points used land map units (LMU) overlaid on thematic maps (land use, soil type, and slope), and were divided into 22 LMUs with three repeats for each LMU. The landslide level was calculated using a cumulative weight score. It was grouped based on the interval formula and modifications to the addition of permeability and soil texture parameters, while the determinants were analyzed using ANOVA and Pearson’s correlation. The results showed that the area was not very low (133.2 ha), low (1,015.33 ha), moderate (1,205.46 ha), high (3,248.48 ha), or very high (734.1 ha). The highest landslide hazard was on steep land (25–45%), and the determining factors were permeability and texture. The steeper the slope and the higher the permeability and soil texture values, the higher the landslide. The recommended landslide mitigation strategies are terracing and minimum tillage on agricultural land. Research on the level of landslides and information on determinant soil characteristics helps stakeholders formulate policies and manage agricultural land on hilly agricultural land.

Recommender systems are vital to everyone's information selection. Managing massive amounts of data is common with recommendation system technology. Annual film releases are rising, and currently films are released within months. With movie releases, apps like Netflix, Viu, Amazon Prime Video, Disney+, etc. have emerged. Thus, Movie Recommender Systems (MRS) are essential to simplify and improve user experience. This research gives a systematic literature review (SLR) of MRS's current condition. Our comprehensive review addresses recommendation algorithms, data processing, and evaluation approaches. In SLR MRS, content-based filtering, collaborative filtering, knowledge-based recommender systems, and hybrid approaches are employed. To achieve this, 66 high-quality studies were selected from 27,187 2019-2023 studies using strict quality criteria. The study found that most MRSs use content-based filtering and machine learning to deliver non-personalized movie suggestions in various domains. The review helps researchers choose MRS development strategies. This study can assist MRS development catch up to other recommendation systems by improving efficiency. The MRS investigation found accuracy, sparsity, scalability, cold start, and operating time issues. Future study will examine how temporal and demographic data affect movie recommendation system relevancy and customization.

Background:Diabetes Mellitus (DM) is a non-communicable disease with an increasing number of sufferers every year, and its negative impacts require special attention. The Indonesian government has taken steps to manage DM by establishing the PROLANIS program. Objective:This study aims to identify the roles of PROLANIS in treating DM in Indonesia. Methods:This study used a scoping review design. We performed extensive searches in CINAHL Plus, Cochrane Library, Embase, PubMed, and Google Scholar. Based on the search results, we found a total of 280 articles. After a selection process, 27 articles met the criteria for review. The papers were grouped by year, study design, setting, and the role of PROLANIS. Results:According to research results, PROLANIS effectively maintains and reduces several essential aspects of DM patients' health, such as body mass index, fasting blood glucose, and HbA1c levels. PROLANIS also plays a positive role in improving the lipid profiles of DM patients. Furthermore, PROLANIS contributes to increasing self-efficacy, self-acceptance, self-management, adherence to therapy, and overall quality of life. Conclusion:PROLANIS positively affects the management of DM by improving physical health and enhancing the quality of life for patients. Keywords:chronic disease; Diabetes Mellitus; non-communicable diseases; PROLANIS

Background: Patients with diabetes mellitus (DM) and cardiovascular disorders who suffer from COVID-19 may have an increased risk of death. Objective: This study aims to analyze the time of death and influencing factors in patients with DM and cardiovascular disorders with COVID-19. Methods: We used a retrospective observational cohort study using medical records of COVID-19 patients treated at Dr Soeradji and Penembahan Senopati hospitals from March 2020 to June 2022. There were 2,959 participants: patients without comorbidities, with DM, and with cardiovascular problems. We extracted sociodemographic and clinical data on patient characteristics using medical records. Data analysis used Kaplan-Meier and Cox regression analysis to estimate survival probability and investigate predictors of death with a 5% significance level. Results: The median survival time was highest in the group without comorbidities (70.00) and lowest in the DM+others group (21.75). Years of treatment, age, presence of comorbidities, and type of hospital were related to the survival rate of COVID-19 patients (p

Hand exoskeleton robots have been developed as rehabilitation robots and assistive devices. Based on the material used, they can be soft or hard exoskeletons. Soft materials such as fabric can be used as a component of the wearable robot to increase comfortability. In this paper, we proposed an affordable soft hand exoskeleton based on fabric and motor-tendon actuation for hand flexion/extension motion assistance in daily activities. On-off control and PI compensator were implemented to regulate finger flexion and extension of the soft exoskeleton. The controllers were embedded into a microcontroller using Simulink software. The input signal command comes from the potentiometer and electromyography (EMG) sensor to drive the flexion/extension movement. Based on the experiments, the proposed controller successfully controlled the exoskeleton hand to facilitate a user in grasping various objects. The proposed soft hand exoskeleton is lightweight, comfortable, portable, and affordable, making it easily manufactured using available hardware and open-source code. The developed soft exoskeleton is a potential assistive device for a person who lost the ability to grasp objects.

The Small Modular Reactor emerges as a recommended technology for nuclear power plant (NPP) development in West Kalimantan, particularly at the Pantai Gosong site. NPP demand highly purified water for cooling system, while seawater contains high TDS, so desalination by utilizing heat and power from NPP, offers a viable solution. Additionally, desalination products can supply freshwater to communities within a 10 km radius, including Sungai Raya and Sungai Raya Island Districts. This study aims to determine the techno-economic aspect of desalination cogeneration with SMR-type NPP for West Kalimantan. The methodologies in this research encompass a comprehensive literature review, a qualitative assessment of desalination technology, and a quantitative economic analysis utilizing the DEEP version 5.1. Techno-economic analysis shows that the simple payback period for MED is 12.3 years, while MSF is 13.9 years. Power lost at MED is 5.3 MWe, while MSF is 9.1 MWe. At a temperature of 30.7 °C, the total water cost of the MED is $1.277 $/m3, while MSF is $1.595 $/m3. MED desalination with temperature 70 °C can be effective using residual heat as an energy source. Cogeneration of MED technology can be option for utilization of heat and power in the context of NPP development in West Kalimantan.

In this research, we show a development process of engagement sub-systems in a blended-learning management system and evaluate the impact of student interaction in the whole system. We develop special sub-systems for engagement purposes via forum, course rating, and class assignment modules. During the system development process, we employ continuous improvement methodology which helps to shorten the software delivery time without disturbing the overall operation. We evaluate the impact of engagement processes in terms of behavioral, emotional and cognitive aspects. Our evaluation results show that by employing the engagement sub-systems we have increased a 0.30 satisfaction point on average (1-5 Likert scale) for 11 evaluation survey questions distributed to 305 students during 2 times evaluation period. Another interesting finding from the surveys is that behavioral (discussion forum and attendance list sub-system) and cognitive (course rating sub-system) aspects have great influences for the students' activities (class assignment sub-system) which finally has a great impact on their cognitive performances.

The Coronavirus disease (COVID-19) pandemic impacted various lines in the international world, including Indonesia. Pandemic COVID-19 in Indonesia has also changed multiple performances in multiple sectors, one of which is education. The concept of learning from home changes lecturers' paradigm as educators in tertiary institutions applying online learning. This study aims to identify students' perceptions of the implementation of online learning during the COVID-19 pandemic. This study uses a qualitative research approach with the type of phenomenology. The subject of this study was 22 students in Indonesia who experienced the impact of the COVID-19 pandemic. This research instrument uses semi-structured interview guidelines. Students perceive online learning during the COVID-19 pandemic as (1) ineffective learning activities; (2) unpleasant learning activities; (3) limit self-actualization in education; (4) helping to become an independent person in learning; and (5) fun learning activities. Higher Education should create innovative and creative online learning strategies. Thus, students have a high enthusiasm for online learning.