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1. Health Related Quality of Life and Associated Factors Among Adult Patients with Rheumatic Heart Disease Patients in Ethiopia

Author: Nasir M, Taddesse K, Ahmed M, Argaw Z, Gebretensaye TG, and Markos S
Subjects: quality of life, rheumatic heart disease, health related quality of life, ethiopia, Medicine (General), R5-920
Abstract: Mohammed Nasir,1 Konno Taddesse,2 Muluken Ahmed,3 Zeleke Argaw,2 Tigistu Gebreyonnis Gebretensaye,2 Sura Markos4 1Pediatrics Department, Hawassa University, Hawassa, Ethiopia; 2Nursing Department, Addis Ababa University, Addis Ababa, Ethiopia; 3Pediatrics Department, Arba Minch University, Arba Minch, Ethiopia; 4Internal Medicine Department, Hawassa University, Hawassa, EthiopiaCorrespondence: Mohammed Nasir, Pediatrics Department, Hawassa University, Hawassa, Ethiopia, Tel +251911739081, Email mn2572338@gmail.comBackground: Quality of life (QOL) is defined as “individuals” perceptions of their position in life. Rheumatic heart disease (RHD) is a consequence of severe, single, or recurrent bouts of acute rheumatic fever. To improve overall patient outcomes, there is currently a greater emphasis on assessing the QOL of these patients. The purpose of this study is to assess the QOL of adult RHD patients who had followed up at St Peter and Tikur Anbessa Hospital, Ethiopia.Methods: An institutional-based cross-sectional study done at St Peter and Tikur Anbessa Hospital, Ethiopia from March 1−June 30/2021 in adult RHD patients. The sample size was 297. Socio-demographic and clinical data were collected using a structured questionnaire. The Amharic version of Short form-36 (SF-36) was used to assess the QOL. A logistic regression model was used to identify associated factors.Results: The study included 297 patients. The majority are female (71%), and half of them are aged between 18− 30 years of age. Of the patiends, 81.1% had no comorbidity, and 15.8% had interventions. RHD affects all domains and summary scores of short form 36 QOL parameters compared to normative values. Age, marital status, place of residence, presence of comorbidity, number of medications, and whether an intervention was done are associated with the QOL of these patients.Conclusion: RHD patients had poor QOL assessed by SF-36. It affects all domains and summary score of short form 36 QOL parameters. Old age, divorce, living in rural areas, associated comorbid conditions, and no intervention done are associated with poor QOL. Identification and treating comorbid conditions and intervention may improve QOL.Keywords: quality of life, rheumatic heart disease, health-related quality of life, Ethiopia, QOL, RHD
Published: 2023

2. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Sheena, B, Hiebert, L, Han, H, Ippolito, H, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abbastabar, H, Abdoli, A, Abubaker Ali, H, Adane, M, Adegboye, O, Adnani, Q, Advani, S, Afzal, M, Afzal, S, Aghaie Meybodi, M, Ahadinezhad, B, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, S, Ahmed, H, Ahmed, M, Rashid, T, Akalu, G, Aklilu, A, Akram, T, Al Hamad, H, Alahdab, F, Alem, A, Alem, D, Alhalaiqa, F, Alhassan, R, Ali, L, Ali, M, Alimohamadi, Y, Alipour, V, Alkhayyat, M, Almustanyir, S, Al-Raddadi, R, Altawalah, H, Amini, S, Amu, H, Ancuceanu, R, Andrei, C, Andrei, T, Anoushiravani, A, Ansar, A, Anyasodor, A, Arabloo, J, Arab-Zozani, M, Argaw, A, Argaw, Z, Arshad, M, Artamonov, A, Ashraf, T, Atlaw, D, Ausloos, F, Ausloos, M, Azadnajafabad, S, Azangou-Khyavy, M, Azari Jafari, A, Azarian, G, Bagheri, S, Bahadory, S, Baig, A, Banach, M, Barati, N, Barrow, A, Batiha, A, Bejarano Ramirez, D, Belgaumi, U, Berhie, A, Bhagat, D, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bhojaraja, V, Bijani, A, Biondi, A, Bodicha, B, Bojia, H, Boloor, A, Bosetti, C, Braithwaite, D, Briko, N, Butt, Z, Camera, L, Chakinala, R, Chakraborty, P, Charan, J, Chen, S, Choi, J, Choudhari, S, Chowdhury, F, Chu, D, Chung, S, Cortesi, P, Cowie, B, Culbreth, G, Dadras, O, Dai, X, Dandona, L, Dandona, R, De La Hoz, F, Debela, S, Dedefo, M, Demeke, F, Demie, T, Demissie, G, Derbew Molla, M, Desta, A, Dhamnetiya, D, Dhimal, M, Didehdar, M, Doan, L, Dorostkar, F, Drake, T, Eghbalian, F, Ekholuenetale, M, El Sayed, I, El Sayed Zaki, M, Elhadi, M, Elmonem, M, Elsharkawy, A, Enany, S, Enyew, D, Erkhembayar, R, Eskandarieh, S, Esmaeilzadeh, F, Ezzikouri, S, Farrokhpour, H, Fetensa, G, Fischer, F, Foroutan, M, Gad, M, Gaidhane, A, Gaidhane, S, Galles, N, Gallus, S, Gebremeskel, T, Gebreyohannes, E, Ghadiri, K, Ghaffari, K, Ghafourifard, M, Ghamari, S, Ghashghaee, A, Gholami, A, Gholizadeh, A, Gilani, A, Goel, A, Golechha, M, Goleij, P, Golinelli, D, Gorini, G, Goshu, Y, Griswold, M, Gubari, M, Gupta, B, Gupta, S, Gupta, V, Haddadi, R, Halwani, R, Hamid, S, Hamidi, S, Hanif, A, Haque, S, Harapan, H, Hargono, A, Hariri, S, Hasaballah, A, Hasan, S, Hassanipour, S, Hassankhani, H, Hay, S, Hayat, K, Heidari, G, Herteliu, C, Heyi, D, Hezam, K, Holla, R, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Huang, J, Hussein, N, Iavicoli, I, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Irham, L, Islam, J, Ismail, N, Jacobsen, K, Jadidi-Niaragh, F, Javadi Mamaghani, A, Jayaram, S, Jayawardena, R, Jebai, R, Jha, R, Joseph, N, Joukar, F, Kaambwa, B, Kabir, A, Kabir, Z, Kalhor, R, Kandel, H, Kanko, T, Kantar, R, Karaye, I, Kassa, B, Kemp Bohan, P, Keykhaei, M, Khader, Y, Khajuria, H, Khan, G, Khan, I, Khan, J, Khan, M, Khanali, J, Khater, A, Khatib, M, Khodadost, M, Khoja, A, Khosravizadeh, O, Khubchandani, J, Kim, G, Kim, H, Kim, M, Kim, Y, Kocarnik, J, Kolahi, A, Koteeswaran, R, Kumar, G, La Vecchia, C, Lal, D, Landires, I, Lasrado, S, Lazarus, J, Ledda, C, Lee, D, Lee, S, Lee, Y, Levi, M, Li, J, Lim, S, Lobo, S, Lopukhov, P, Loureiro, J, Maclachlan, J, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Majeed, A, Makki, A, Malekpour, M, Malekzadeh, R, Malik, A, Mansour-Ghanaei, F, Mansournia, M, Martins-Melo, F, Matthews, P, Mendoza, W, Menezes, R, Meretoja, T, Mersha, A, Mestrovic, T, Miller, T, Minh, L, Mirica, A, Mirmoeeni, S, Mirrakhimov, E, Misra, S, Mithra, P, Moazen, B, Mohamadkhani, A, Mohammadi, M, Mohammed, S, Moka, N, Mokdad, A, Moludi, J, Momtazmanesh, S, Monasta, L, Moradi, G, Moradzadeh, M, Moradzadeh, R, Moraga, P, Mostafavi, E, Mubarik, S, Muniyandi, M, Murray, C, Naghavi, M, Naimzada, M, Narasimha Swamy, S, Natto, Z, Nayak, B, Nazari, J, Negoi, I, Negru, S, Nejadghaderi, S, Neupane Kandel, S, Nguyen, H, Ngwa, C, Niazi, R, Nnaji, C, Noubiap, J, Nowroozi, A, Nunez-Samudio, V, Oancea, B, Ochir, C, Odukoya, O, Oh, I, Olagunju, A, Olakunde, B, Omar Bali, A, Omer, E, Otstavnov, S, Oumer, B, Padubidri, J, Pana, A, Pandey, A, Park, E, Pashazadeh Kan, F, Patel, U, Paudel, U, Petcu, I, Piracha, Z, Pollok, R, Postma, M, Pourshams, A, Poustchi, H, Rabiee, M, Rabiee, N, Rafiei, A, Rafiei, S, Raghuram, P, Rahman, M, Rahmani, A, Rahmawaty, S, Rajesh, A, Ranasinghe, P, Rao, C, Rao, S, Rashidi, M, Rawaf, D, Rawaf, S, Rawassizadeh, R, Rezaei, N, Rezapour, A, Rezazadeh-Khadem, S, Rodriguez, J, Rwegerera, G, Sabour, S, Saddik, B, Saeb, M, Saeed, U, Sahebkar, A, Saif-Ur-Rahman, K, Salahi, S, Salimzadeh, H, Sampath, C, Samy, A, Sanabria, J, Sanmarchi, F, Santric-Milicevic, M, Sarveazad, A, Sathian, B, Sawhney, M, Seidu, A, Sepanlou, S, Seylani, A, Shahabi, S, Shaikh, M, Shaker, E, Shakhmardanov, M, Shannawaz, M, Shenoy, S, Shetty, J, Shetty, P, Shibuya, K, Shin, J, Shobeiri, P, Sibhat, M, Singh, A, Singh, J, Singh, S, Skryabin, V, Skryabina, A, Sohrabpour, A, Song, S, Tabaeian, S, Tadesse, E, Taheri, M, Tampa, M, Tan, K, Tavakoli, A, Tbakhi, A, Tefera, B, Tehrani-Banihashemi, A, Tesfaw, H, Thapar, R, Thavamani, A, Tohidast, S, Tollosa, D, Tosti, M, Tovani-Palone, M, Traini, E, Tran, M, Trihandini, I, Tusa, B, Ullah, I, Vacante, M, Valadan Tahbaz, S, Valdez, P, Varthya, S, Vo, B, Waheed, Y, Weldesenbet, A, Woldemariam, M, Xu, S, Yahyazadeh Jabbari, S, Yaseri, M, Yeshaw, Y, Yigit, V, Yirdaw, B, Yonemoto, N, Yu, C, Yunusa, I, Zahir, M, Zaki, L, Zamani, M, Zamanian, M, Zastrozhin, M, Vos, T, Ward, J, Dirac, M, Sheena B. S., Hiebert L., Han H., Ippolito H., Abbasi-Kangevari M., Abbasi-Kangevari Z., Abbastabar H., Abdoli A., Abubaker Ali H., Adane M. M., Adegboye O. A., Adnani Q. E. S., Advani S. M., Afzal M. S., Afzal S., Aghaie Meybodi M., Ahadinezhad B., Ahinkorah B. O., Ahmad S., Ahmad T., Ahmadi S., Ahmed H., Ahmed M. B., Rashid T. A., Akalu G. T., Aklilu A., Akram T., Al Hamad H., Alahdab F., Alem A., Alem D. T., Alhalaiqa F. A. N., Alhassan R. K., Ali L., Ali M. A., Alimohamadi Y., Alipour V., Alkhayyat M., Almustanyir S., Al-Raddadi R. M., Altawalah H., Amini S., Amu H., Ancuceanu R., Andrei C. L., Andrei T., Anoushiravani A., Ansar A., Anyasodor A. E., Arabloo J., Arab-Zozani M., Argaw A. M., Argaw Z. G., Arshad M., Artamonov A. A., Ashraf T., Atlaw D., Ausloos F., Ausloos M., Azadnajafabad S., Azangou-Khyavy M., Azari Jafari A., Azarian G., Bagheri S., Bahadory S., Baig A. A., Banach M., Barati N., Barrow A., Batiha A. -M. M., Bejarano Ramirez D. F., Belgaumi U. I., Berhie A. Y., Bhagat D. S., Bhardwaj N., Bhardwaj P., Bhattacharyya K., Bhojaraja V. S., Bijani A., Biondi A., Bodicha B. B. A., Bojia H. A., Boloor A., Bosetti C., Braithwaite D., Briko N. I., Butt Z. A., Camera L. A., Chakinala R. C., Chakraborty P. A., Charan J., Chen S., Choi J. -Y. J., Choudhari S. G., Chowdhury F. R., Chu D. -T., Chung S. -C., Cortesi P. A., Cowie B. C., Culbreth G. T., Dadras O., Dai X., Dandona L., Dandona R., De La Hoz F. P., Debela S. A., Dedefo M. G., Demeke F. M., Demie T. G. G., Demissie G. D., Derbew Molla M., Desta A. A., Dhamnetiya D., Dhimal M. L., Dhimal M., Didehdar M., Doan L. P., Dorostkar F., Drake T. M., Eghbalian F., Ekholuenetale M., El Sayed I., El Sayed Zaki M., Elhadi M., Elmonem M. A., Elsharkawy A., Enany S., Enyew D. B., Erkhembayar R., Eskandarieh S., Esmaeilzadeh F., Ezzikouri S., Farrokhpour H., Fetensa G., Fischer F., Foroutan M., Gad M. M., Gaidhane A. M., Gaidhane S., Galles N. C., Gallus S., Gebremeskel T. G., Gebreyohannes E. A., Ghadiri K., Ghaffari K., Ghafourifard M., Ghamari S. -H., Ghashghaee A., Gholami A., Gholizadeh A., Gilani A., Goel A., Golechha M., Goleij P., Golinelli D., Gorini G., Goshu Y. A., Griswold M. G., Gubari M. I. M., Gupta B., Gupta S., Gupta V. B., Gupta V. K., Haddadi R., Halwani R., Hamid S. S., Hamidi S., Hanif A., Haque S., Harapan H., Hargono A., Hariri S., Hasaballah A. I., Hasan S. M. M., Hassanipour S., Hassankhani H., Hay S. I., Hayat K., Heidari G., Herteliu C., Heyi D. Z., Hezam K., Holla R., Hosseini M. -S., Hosseini M., Hosseinzadeh M., Hostiuc M., Househ M., Huang J., Hussein N. R., Iavicoli I., Ibitoye S. E., Ilesanmi O. S., Ilic I. M., Ilic M. D., Irham L. M., Islam J. Y., Ismail N. E., Jacobsen K. H., Jadidi-Niaragh F., Javadi Mamaghani A., Jayaram S., Jayawardena R., Jebai R., Jha R. P., Joseph N., Joukar F., Kaambwa B., Kabir A., Kabir Z., Kalhor R., Kandel H., Kanko T. K. T., Kantar R. S., Karaye I. M., Kassa B. G., Kemp Bohan P. M., Keykhaei M., Khader Y. S., Khajuria H., Khan G., Khan I. A., Khan J., Khan M. A., Khanali J., Khater A. M., Khatib M. N., Khodadost M., Khoja A. T., Khosravizadeh O., Khubchandani J., Kim G. R., Kim H., Kim M. S., Kim Y. J., Kocarnik J. M., Kolahi A. -A., Koteeswaran R., Kumar G. A., La Vecchia C., Lal D. K., Landires I., Lasrado S., Lazarus J. V., Ledda C., Lee D. W., Lee S. -W., Lee Y. Y., Levi M., Li J., Lim S. S., Lobo S. W., Lopukhov P. D., Loureiro J. A., MacLachlan J. H., Magdy Abd El Razek H., Magdy Abd El Razek M., Majeed A., Makki A., Malekpour M. -R., Malekzadeh R., Malik A. A., Mansour-Ghanaei F., Mansournia M. A., Martins-Melo F. R., Matthews P. C., Mendoza W., Menezes R. G., Meretoja T. J., Mersha A. G., Mestrovic T., Miller T. R., Minh L. H. N., Mirica A., Mirmoeeni S., Mirrakhimov E. M., Misra S., Mithra P., Moazen B., Mohamadkhani A., Mohammadi M., Mohammed S., Moka N., Mokdad A. H., Moludi J., Momtazmanesh S., Monasta L., Moradi G., Moradzadeh M., Moradzadeh R., Moraga P., Mostafavi E., Mubarik S., Muniyandi M., Murray C. J. L., Naghavi M., Naimzada M. D., Narasimha Swamy S., Natto Z. S., Nayak B. P., Nazari J., Negoi I., Negru S. M., Nejadghaderi S. A., Neupane Kandel S., Nguyen H. L. T., Ngwa C. H., Niazi R. K., Nnaji C. A., Noubiap J. J., Nowroozi A., Nunez-Samudio V., Oancea B., Ochir C., Odukoya O. O., Oh I. -H., Olagunju A. T., Olakunde B. O., Omar Bali A., Omer E., Otstavnov S. S., Oumer B., Padubidri J. R., Pana A., Pandey A., Park E. -C., Pashazadeh Kan F., Patel U. K., Paudel U., Petcu I. -R., Piracha Z. Z., Pollok R. C. G., Postma M. J., Pourshams A., Poustchi H., Rabiee M., Rabiee N., Rafiei A., Rafiei S., Raghuram P. M., Rahman M., Rahmani A. M., Rahmawaty S., Rajesh A., Ranasinghe P., Rao C. R., Rao S. J., Rashidi M., Rashidi M. -M., Rawaf D. L., Rawaf S., Rawassizadeh R., Rezaei N., Rezapour A., Rezazadeh-Khadem S., Rodriguez J. A. B., Rwegerera G. M., Sabour S., Saddik B., Saeb M. R., Saeed U., Sahebkar A., Saif-Ur-Rahman K. M., Salahi S., Salimzadeh H., Sampath C., Samy A. M., Sanabria J., Sanmarchi F., Santric-Milicevic M. M., Sarveazad A., Sathian B., Sawhney M., Seidu A. -A., Sepanlou S. G., Seylani A., Shahabi S., Shaikh M. A., Shaker E., Shakhmardanov M. Z., Shannawaz M., Shenoy S. M., Shetty J. K., Shetty P. H., Shibuya K., Shin J. I., Shobeiri P., Sibhat M. M., Singh A. D., Singh J. A., Singh S., Skryabin V. Y., Skryabina A. A., Sohrabpour A. A., Song S., Tabaeian S. P., Tadesse E. G., Taheri M., Tampa M., Tan K. -K., Tavakoli A., Tbakhi A., Tefera B. N., Tehrani-Banihashemi A., Tesfaw H. M., Thapar R., Thavamani A., Tohidast S. A., Tollosa D. N., Tosti M. E., Tovani-Palone M. R., Traini E., Tran M. T. N., Trihandini I., Tusa B. S., Ullah I., Vacante M., Valadan Tahbaz S., Valdez P. R., Varthya S. B., Vo B., Waheed Y., Weldesenbet A. B., Woldemariam M., Xu S., Yahyazadeh Jabbari S. H., Yaseri M., Yeshaw Y., Yigit V., Yirdaw B. W., Yonemoto N., Yu C., Yunusa I., Zahir M., Zaki L., Zamani M., Zamanian M., Zastrozhin M. S., Vos T., Ward J. W., Dirac M. A., Sheena, B, Hiebert, L, Han, H, Ippolito, H, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abbastabar, H, Abdoli, A, Abubaker Ali, H, Adane, M, Adegboye, O, Adnani, Q, Advani, S, Afzal, M, Afzal, S, Aghaie Meybodi, M, Ahadinezhad, B, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, S, Ahmed, H, Ahmed, M, Rashid, T, Akalu, G, Aklilu, A, Akram, T, Al Hamad, H, Alahdab, F, Alem, A, Alem, D, Alhalaiqa, F, Alhassan, R, Ali, L, Ali, M, Alimohamadi, Y, Alipour, V, Alkhayyat, M, Almustanyir, S, Al-Raddadi, R, Altawalah, H, Amini, S, Amu, H, Ancuceanu, R, Andrei, C, Andrei, T, Anoushiravani, A, Ansar, A, Anyasodor, A, Arabloo, J, Arab-Zozani, M, Argaw, A, Argaw, Z, Arshad, M, Artamonov, A, Ashraf, T, Atlaw, D, Ausloos, F, Ausloos, M, Azadnajafabad, S, Azangou-Khyavy, M, Azari Jafari, A, Azarian, G, Bagheri, S, Bahadory, S, Baig, A, Banach, M, Barati, N, Barrow, A, Batiha, A, Bejarano Ramirez, D, Belgaumi, U, Berhie, A, Bhagat, D, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bhojaraja, V, Bijani, A, Biondi, A, Bodicha, B, Bojia, H, Boloor, A, Bosetti, C, Braithwaite, D, Briko, N, Butt, Z, Camera, L, Chakinala, R, Chakraborty, P, Charan, J, Chen, S, Choi, J, Choudhari, S, Chowdhury, F, Chu, D, Chung, S, Cortesi, P, Cowie, B, Culbreth, G, Dadras, O, Dai, X, Dandona, L, Dandona, R, De La Hoz, F, Debela, S, Dedefo, M, Demeke, F, Demie, T, Demissie, G, Derbew Molla, M, Desta, A, Dhamnetiya, D, Dhimal, M, Didehdar, M, Doan, L, Dorostkar, F, Drake, T, Eghbalian, F, Ekholuenetale, M, El Sayed, I, El Sayed Zaki, M, Elhadi, M, Elmonem, M, Elsharkawy, A, Enany, S, Enyew, D, Erkhembayar, R, Eskandarieh, S, Esmaeilzadeh, F, Ezzikouri, S, Farrokhpour, H, Fetensa, G, Fischer, F, Foroutan, M, Gad, M, Gaidhane, A, Gaidhane, S, Galles, N, Gallus, S, Gebremeskel, T, Gebreyohannes, E, Ghadiri, K, Ghaffari, K, Ghafourifard, M, Ghamari, S, Ghashghaee, A, Gholami, A, Gholizadeh, A, Gilani, A, Goel, A, Golechha, M, Goleij, P, Golinelli, D, Gorini, G, Goshu, Y, Griswold, M, Gubari, M, Gupta, B, Gupta, S, Gupta, V, Haddadi, R, Halwani, R, Hamid, S, Hamidi, S, Hanif, A, Haque, S, Harapan, H, Hargono, A, Hariri, S, Hasaballah, A, Hasan, S, Hassanipour, S, Hassankhani, H, Hay, S, Hayat, K, Heidari, G, Herteliu, C, Heyi, D, Hezam, K, Holla, R, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Huang, J, Hussein, N, Iavicoli, I, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Irham, L, Islam, J, Ismail, N, Jacobsen, K, Jadidi-Niaragh, F, Javadi Mamaghani, A, Jayaram, S, Jayawardena, R, Jebai, R, Jha, R, Joseph, N, Joukar, F, Kaambwa, B, Kabir, A, Kabir, Z, Kalhor, R, Kandel, H, Kanko, T, Kantar, R, Karaye, I, Kassa, B, Kemp Bohan, P, Keykhaei, M, Khader, Y, Khajuria, H, Khan, G, Khan, I, Khan, J, Khan, M, Khanali, J, Khater, A, Khatib, M, Khodadost, M, Khoja, A, Khosravizadeh, O, Khubchandani, J, Kim, G, Kim, H, Kim, M, Kim, Y, Kocarnik, J, Kolahi, A, Koteeswaran, R, Kumar, G, La Vecchia, C, Lal, D, Landires, I, Lasrado, S, Lazarus, J, Ledda, C, Lee, D, Lee, S, Lee, Y, Levi, M, Li, J, Lim, S, Lobo, S, Lopukhov, P, Loureiro, J, Maclachlan, J, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Majeed, A, Makki, A, Malekpour, M, Malekzadeh, R, Malik, A, Mansour-Ghanaei, F, Mansournia, M, Martins-Melo, F, Matthews, P, Mendoza, W, Menezes, R, Meretoja, T, Mersha, A, Mestrovic, T, Miller, T, Minh, L, Mirica, A, Mirmoeeni, S, Mirrakhimov, E, Misra, S, Mithra, P, Moazen, B, Mohamadkhani, A, Mohammadi, M, Mohammed, S, Moka, N, Mokdad, A, Moludi, J, Momtazmanesh, S, Monasta, L, Moradi, G, Moradzadeh, M, Moradzadeh, R, Moraga, P, Mostafavi, E, Mubarik, S, Muniyandi, M, Murray, C, Naghavi, M, Naimzada, M, Narasimha Swamy, S, Natto, Z, Nayak, B, Nazari, J, Negoi, I, Negru, S, Nejadghaderi, S, Neupane Kandel, S, Nguyen, H, Ngwa, C, Niazi, R, Nnaji, C, Noubiap, J, Nowroozi, A, Nunez-Samudio, V, Oancea, B, Ochir, C, Odukoya, O, Oh, I, Olagunju, A, Olakunde, B, Omar Bali, A, Omer, E, Otstavnov, S, Oumer, B, Padubidri, J, Pana, A, Pandey, A, Park, E, Pashazadeh Kan, F, Patel, U, Paudel, U, Petcu, 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S., Hiebert L., Han H., Ippolito H., Abbasi-Kangevari M., Abbasi-Kangevari Z., Abbastabar H., Abdoli A., Abubaker Ali H., Adane M. M., Adegboye O. A., Adnani Q. E. S., Advani S. M., Afzal M. S., Afzal S., Aghaie Meybodi M., Ahadinezhad B., Ahinkorah B. O., Ahmad S., Ahmad T., Ahmadi S., Ahmed H., Ahmed M. B., Rashid T. A., Akalu G. T., Aklilu A., Akram T., Al Hamad H., Alahdab F., Alem A., Alem D. T., Alhalaiqa F. A. N., Alhassan R. K., Ali L., Ali M. A., Alimohamadi Y., Alipour V., Alkhayyat M., Almustanyir S., Al-Raddadi R. M., Altawalah H., Amini S., Amu H., Ancuceanu R., Andrei C. L., Andrei T., Anoushiravani A., Ansar A., Anyasodor A. E., Arabloo J., Arab-Zozani M., Argaw A. M., Argaw Z. G., Arshad M., Artamonov A. A., Ashraf T., Atlaw D., Ausloos F., Ausloos M., Azadnajafabad S., Azangou-Khyavy M., Azari Jafari A., Azarian G., Bagheri S., Bahadory S., Baig A. A., Banach M., Barati N., Barrow A., Batiha A. -M. M., Bejarano Ramirez D. F., Belgaumi U. I., Berhie A. Y., Bhagat D. 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H., Yaseri M., Yeshaw Y., Yigit V., Yirdaw B. W., Yonemoto N., Yu C., Yunusa I., Zahir M., Zaki L., Zamani M., Zamanian M., Zastrozhin M. S., Vos T., Ward J. W., and Dirac M. A.
Abstract: Background: Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). We estimated the global, regional, and national prevalence of hepatitis B virus (HBV), as well as mortality and disability-adjusted life-years (DALYs) due to HBV, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This included estimates for 194 WHO member states, for which we compared our estimates to WHO elimination targets. Methods: The primary data sources were population-based serosurveys, claims and hospital discharges, cancer registries, vital registration systems, and published case series. We estimated chronic HBV infection and the burden of HBV-related diseases, defined as an aggregate of cirrhosis due to hepatitis B, liver cancer due to hepatitis B, and acute hepatitis B. We used DisMod-MR 2.1, a Bayesian mixed-effects meta-regression tool, to estimate the prevalence of chronic HBV infection, cirrhosis, and aetiological proportions of cirrhosis. We used mortality-to-incidence ratios modelled with spatiotemporal Gaussian process regression to estimate the incidence of liver cancer. We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-of-sample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B. Findings: In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4·1% (95% uncertainty interval [UI] 3·7 to 4·5), corresponding to 316 million (284 to 351) infected people. There was a 31·3% (29·0 to 33·9) decline in all-age prevalence between 1990 and 2019, with a more marked decline of 76·8% (76·2 to 77·5) in prevalence in children younger than 5 years. HBV-related diseases resulted in 555 0
Published: 2022

3. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

Author: Kyu, H, Vongpradith, A, Sirota, S, Novotney, A, Troeger, C, Doxey, M, Bender, R, Ledesma, J, Biehl, M, Albertson, S, Frostad, J, Burkart, K, Bennitt, F, Zhao, J, Gardner, W, Hagins, H, Bryazka, D, Dominguez, R, Abate, S, Abdelmasseh, M, Abdoli, A, Abdoli, G, Abedi, A, Abedi, V, Abegaz, T, Abidi, H, Aboagye, R, Abolhassani, H, Abtew, Y, Abubaker Ali, H, Abu-Gharbieh, E, Abu-Zaid, A, Adamu, K, Addo, I, Adegboye, O, Adnan, M, Adnani, Q, Afzal, M, Afzal, S, Ahinkorah, B, Ahmad, A, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, H, Ahmed, J, Ahmed Rashid, T, Akbarzadeh-Khiavi, M, Al Hamad, H, Albano, L, Aldeyab, M, Alemu, B, Alene, K, Algammal, A, Alhalaiqa, F, Alhassan, R, Ali, B, Ali, L, Ali, M, Ali, S, Alimohamadi, Y, Alipour, V, Al-Jumaily, A, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Al-Rifai, R, Alryalat, S, Alvis-Guzman, N, Alvis-Zakzuk, N, Ameyaw, E, Aminian Dehkordi, J, Amuasi, J, Amugsi, D, Anbesu, E, Ansar, A, Anyasodor, A, Arabloo, J, Areda, D, Argaw, A, Argaw, Z, Arulappan, J, 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Abstract: Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates decl
Published: 2022

4. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Brittney S Sheena, Lindsey Hiebert, Hannah Han, Helen Ippolito, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Amir Abdoli, Hiwa Abubaker Ali, Mesafint Molla Adane, Oyelola A Adegboye, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad Sohail Afzal, Saira Afzal, Mohamad Aghaie Meybodi, Bahman Ahadinezhad, Bright Opoku Ahinkorah, Sajjad Ahmad, Tauseef Ahmad, Sepideh Ahmadi, Haroon Ahmed, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Gizachew Taddesse Akalu, Addis Aklilu, Tayyaba Akram, Hanadi Al Hamad, Fares Alahdab, Adugnaw Zeleke Alem, Dejene Tsegaye Alem, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Liaqat Ali, Muhammad Ashar Ali, Yousef Alimohamadi, Vahid Alipour, Motasem Alkhayyat, Sami Almustanyir, Rajaa M Al-Raddadi, Haya Altawalah, Saeed Amini, Hubert Amu, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Amir Anoushiravani, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Ayele Mamo Argaw, Zeleke Gebru Argaw, Muhammad Arshad, Anton A Artamonov, Tahira Ashraf, Daniel Atlaw, Floriane Ausloos, Marcel Ausloos, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Ghasem Azarian, Sayna Bagheri, Saeed Bahadory, Atif Amin Baig, Maciej Banach, Nastaran Barati, Amadou Barrow, Abdul-Monim Mohammad Batiha, Diana Fernanda Bejarano Ramirez, Uzma Iqbal Belgaumi, Alemshet Yirga Berhie, Devidas S Bhagat, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Ali Bijani, Antonio Biondi, Belay Boda Abule Bodicha, Hunduma Amensisa Bojia, Archith Boloor, Cristina Bosetti, Dejana Braithwaite, Nikolay Ivanovich Briko, Zahid A Butt, Luis Alberto Cámera, Raja Chandra Chakinala, Promit Ananyo Chakraborty, Jaykaran Charan, Shu Chen, Jee-Young Jasmine Choi, Sonali Gajanan Choudhari, Fazle Rabbi Chowdhury, Dinh-Toi Chu, Sheng-Chia Chung, Paolo Angelo Cortesi, Benjamin C Cowie, Garland T Culbreth, Omid Dadras, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Fernando Pio De la Hoz, Sisay Abebe Debela, Mohammed Gebre Dedefo, Feleke Mekonnen Demeke, Takele Gezahegn G Demie, Getu Debalkie Demissie, Meseret Derbew Molla, Abebaw Alemayehu Desta, Deepak Dhamnetiya, Mandira Lamichhane Dhimal, Meghnath Dhimal, Mojtaba Didehdar, Linh Phuong Doan, Fariba Dorostkar, Thomas M Drake, Fatemeh Eghbalian, Michael Ekholuenetale, Iman El Sayed, Maysaa El Sayed Zaki, Muhammed Elhadi, Mohamed A Elmonem, Aisha Elsharkawy, Shymaa Enany, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Sharareh Eskandarieh, Firooz Esmaeilzadeh, Sayeh Ezzikouri, Hossein Farrokhpour, Getahun Fetensa, Florian Fischer, Masoud Foroutan, Mohamed M Gad, Abhay Motiramji Gaidhane, Shilpa Gaidhane, Natalie C Galles, Silvano Gallus, Teferi Gebru Gebremeskel, Eyob Alemayehu Gebreyohannes, Keyghobad Ghadiri, Kazem Ghaffari, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Ali Gholami, Abdolmajid Gholizadeh, Aima Gilani, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Giuseppe Gorini, Yitayal Ayalew Goshu, Max G Griswold, Mohammed Ibrahim Mohialdeen Gubari, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Rabih Halwani, Saeed S Hamid, Samer Hamidi, Asif Hanif, Shafiul Haque, Harapan Harapan, Arief Hargono, Sanam Hariri, Ahmed I Hasaballah, S M Mahmudul Hasan, Soheil Hassanipour, Hadi Hassankhani, Simon I Hay, Khezar Hayat, Golnaz Heidari, Claudiu Herteliu, Demisu Zenbaba Heyi, Kamal Hezam, Ramesh Holla, Mohammad-Salar Hosseini, Mostafa Hosseini, Mehdi Hosseinzadeh, Mihaela Hostiuc, Mowafa Househ, Junjie Huang, Nawfal R Hussein, Ivo Iavicoli, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Lalu Muhammad Irham, Jessica Y Islam, Nahlah Elkudssiah Ismail, Kathryn H Jacobsen, Farhad Jadidi-Niaragh, Amirreza Javadi Mamaghani, Shubha Jayaram, Ranil Jayawardena, Rime Jebai, Ravi Prakash Jha, Nitin Joseph, Farahnaz Joukar, Billingsley Kaambwa, Ali Kabir, Zubair Kabir, Rohollah Kalhor, 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Subjects: Liver Cirrhosis, Hepatology, Seroepidemiologic Studies, 3121 General medicine, internal medicine and other clinical medicine, Liver Neoplasms, Gastroenterology, Humans, Bayes Theorem, HBV, Global burden of diseases, HCC, Cirrhosis, Child, Hepatitis B, Global Burden of Disease
Abstract: Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). We estimated the global, regional, and national prevalence of hepatitis B virus (HBV), as well as mortality and disability-adjusted life-years (DALYs) due to HBV, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This included estimates for 194 WHO member states, for which we compared our estimates to WHO elimination targets. Methods: The primary data sources were population-based serosurveys, claims and hospital discharges, cancer registries, vital registration systems, and published case series. We estimated chronic HBV infection and the burden of HBV-related diseases, defined as an aggregate of cirrhosis due to hepatitis B, liver cancer due to hepatitis B, and acute hepatitis B. We used DisMod-MR 2.1, a Bayesian mixed-effects meta-regression tool, to estimate the prevalence of chronic HBV infection, cirrhosis, and aetiological proportions of cirrhosis. We used mortality-to-incidence ratios modelled with spatiotemporal Gaussian process regression to estimate the incidence of liver cancer. We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-of-sample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B. Findings: In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4·1% (95% uncertainty interval [UI] 3·7 to 4·5), corresponding to 316 million (284 to 351) infected people. There was a 31·3% (29·0 to 33·9) decline in all-age prevalence between 1990 and 2019, with a more marked decline of 76·8% (76·2 to 77·5) in prevalence in children younger than 5 years. HBV-related diseases resulted in 555 000 global deaths (487 000 to 630 000) in 2019. The number of HBV-related deaths increased between 1990 and 2019 (by 5·9% [–5·6 to 19·2]) and between 2015 and 2019 (by 2·9% [–5·9 to 11·3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. As of 2019, 68 of 194 countries had already achieved the 2030 target proposed in WHO Interim Guidance of an all-age HBV-related death rate of four per 100 000. Interpretation: The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination. HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and cohort effects. By 2019, many countries had met the interim seroprevalence target for children younger than 5 years, but few countries had met the WHO-GHSS interim targets for deaths and new cases. Progress according to all indicators must be accelerated to meet 2030 targets, and there are marked disparities in burden and progress across the world. HBV interventions, such as vaccination, testing, and treatment, must be strategically supported and scaled up to achieve elimination. Funding: Bill & Melinda Gates Foundation.
Published: 2022

5. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

Author: Hmwe Hmwe Kyu, Avina Vongpradith, Sarah Brooke Sirota, Amanda Novotney, Christopher E Troeger, Matthew C Doxey, Rose G Bender, Jorge R Ledesma, Molly H Biehl, Samuel B Albertson, Joseph Jon Frostad, Katrin Burkart, Fiona B Bennitt, Jeff T Zhao, William M Gardner, Hailey Hagins, Dana Bryazka, Regina-Mae Villanueva Dominguez, Semagn Mekonnen Abate, Michael Abdelmasseh, Amir Abdoli, Gholamreza Abdoli, Aidin Abedi, Vida Abedi, Tadesse M Abegaz, Hassan Abidi, Richard Gyan Aboagye, Hassan Abolhassani, Yonas Derso Abtew, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Ahmed Abu-Zaid, Kidist Adamu, Isaac Yeboah Addo, Oyelola A Adegboye, Mohammad Adnan, Qorinah Estiningtyas Sakilah Adnani, Muhammad Sohail Afzal, Saira Afzal, Bright Opoku Ahinkorah, Aqeel Ahmad, Araz Ramazan Ahmad, Sajjad Ahmad, Ali Ahmadi, Sepideh Ahmadi, Haroon Ahmed, Jivan Qasim Ahmed, Tarik Ahmed Rashid, Mostafa Akbarzadeh-Khiavi, Hanadi Al Hamad, Luciana Albano, Mamoon A Aldeyab, Bezatu Mengistie Alemu, Kefyalew Addis Alene, Abdelazeem M Algammal, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Beriwan Abdulqadir Ali, Liaqat Ali, Musa Mohammed Ali, Syed Shujait Ali, Yousef Alimohamadi, Vahid Alipour, Adel Al-Jumaily, Syed Mohamed Aljunid, Sami Almustanyir, Rajaa M Al-Raddadi, Rami H Hani Al-Rifai, Saif Aldeen S AlRyalat, Nelson Alvis-Guzman, Nelson J Alvis-Zakzuk, Edward Kwabena Ameyaw, Javad Javad Aminian Dehkordi, John H Amuasi, Dickson A Amugsi, Etsay Woldu Anbesu, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Demelash Areda, Ayele Mamo Argaw, Zeleke Gebru Argaw, Judie Arulappan, Raphael Taiwo Aruleba, Mulusew A Asemahagn, Seyyed Shamsadin Athari, Daniel Atlaw, Engi F Attia, Sameh Attia, Avinash Aujayeb, Tewachew Awoke, Tegegn Mulatu Ayana, Martin Amogre Ayanore, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Samad Azari, Amirhossein Azari Jafari, Muhammad Badar, Ashish D Badiye, Nayereh Baghcheghi, Sara Bagherieh, Atif Amin Baig, Maciej Banach, Indrajit Banerjee, Mainak Bardhan, 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Iyinoluwa Olufadewa, Ahmed Omar Bali, Emad Omer, Eyal Oren, Erika Ota, Nikita Otstavnov, Abderrahim Oulhaj, Mahesh P A, Jagadish Rao Padubidri, Keyvan Pakshir, Reza Pakzad, Tamás Palicz, Anamika Pandey, Suman Pant, Shahina Pardhan, Eun-Cheol Park, Eun-Kee Park, Fatemeh Pashazadeh Kan, Rajan Paudel, Shrikant Pawar, Minjin Peng, Gavin Pereira, Simone Perna, Navaraj Perumalsamy, Ionela-Roxana Petcu, David M Pigott, Zahra Zahid Piracha, Vivek Podder, Roman V Polibin, Maarten J Postma, Hamid Pourasghari, Naeimeh Pourtaheri, Mirza Muhammad Fahd Qadir, Mathieu Raad, Mohammad Rabiee, Navid Rabiee, Saber Raeghi, Alireza Rafiei, Fakher Rahim, Mehran Rahimi, Vafa Rahimi-Movaghar, Azizur Rahman, Md Obaidur Rahman, Mosiur Rahman, Muhammad Aziz Rahman, Amir Masoud Rahmani, Vahid Rahmanian, Pradhum Ram, Kiana Ramezanzadeh, Juwel Rana, Priyanga Ranasinghe, Usha Rani, Sowmya J Rao, Sina Rashedi, Mohammad-Mahdi Rashidi, Azad Rasul, Zubair Ahmed Ratan, David Laith Rawaf, Salman Rawaf, Reza Rawassizadeh, Mohammad Sadegh Razeghinia, Elrashdy Moustafa Mohamed Redwan, Marissa B Reitsma, Andre M N Renzaho, Mohsen Rezaeian, Abanoub Riad, Reza Rikhtegar, Jefferson Antonio Buendia Rodriguez, Emma L B Rogowski, Luca Ronfani, Kristina E Rudd, Basema Saddik, Erfan Sadeghi, Umar Saeed, Azam Safary, Sher Zaman Safi, Maryam Sahebazzamani, Amirhossein Sahebkar, Sateesh Sakhamuri, Sana Salehi, Muhammad Salman, Hossein Samadi Kafil, Abdallah M Samy, Milena M Santric-Milicevic, Bruno Piassi Sao Jose, Maryam Sarkhosh, Brijesh Sathian, Monika Sawhney, Ganesh Kumar Saya, Abdul-Aziz Seidu, Allen Seylani, Amira A Shaheen, Masood Ali Shaikh, Elaheh Shaker, Hina Shamshad, Mequannent Melaku Sharew, Asaad Sharhani, Azam Sharifi, Purva Sharma, Ali Sheidaei, Suchitra M Shenoy, Jeevan K Shetty, Damtew Solomon Shiferaw, Mika Shigematsu, Jae Il Shin, Hesamaddin Shirzad-Aski, K M Shivakumar, Siddharudha Shivalli, Parnian Shobeiri, Wudneh Simegn, Colin R Simpson, Harpreet Singh, Jasvinder A Singh, Paramdeep Singh, Samarjeet Singh Siwal, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Mohammad Sadegh Soltani-Zangbar, Suhang Song, Yimeng Song, Prashant Sood, Chandrashekhar T Sreeramareddy, Paschalis Steiropoulos, Muhammad Suleman, Seyed-Amir Tabatabaeizadeh, Alireza Tahamtan, Majid Taheri, Moslem Taheri Soodejani, Elahe Taki, Iman M Talaat, Mircea Tampa, Sarmila Tandukar, Nathan Y Tat, Vivian Y Tat, Yibekal Manaye Tefera, Gebremaryam Temesgen, Mohamad-Hani Temsah, Azene Tesfaye, Degefa Gomora Tesfaye, Belay Tessema, Rekha Thapar, Jansje Henny Vera Ticoalu, Amir Tiyuri, Imad I Tleyjeh, Munkhsaikhan Togtmol, Marcos Roberto Tovani-Palone, Derara Girma Tufa, Irfan Ullah, Era Upadhyay, Sahel Valadan Tahbaz, Pascual R Valdez, Rohollah Valizadeh, Constantine Vardavas, Tommi Juhani Vasankari, Bay Vo, Linh Gia Vu, Birhanu Wagaye, Yasir Waheed, Yu Wang, Abdul Waris, T Eoin West, Nuwan Darshana Wickramasinghe, Xiaoyue Xu, Sajad Yaghoubi, Gahin Abdulraheem Tayib Yahya, Seyed Hossein Yahyazadeh Jabbari, Dong Keon Yon, Naohiro Yonemoto, Burhan Abdullah Zaman, Alireza Zandifar, Moein Zangiabadian, Heather J Zar, Iman Zare, Zahra Zareshahrabadi, Armin Zarrintan, Mikhail Sergeevich Zastrozhin, Wu Zeng, Mengxi Zhang, Zhi-Jiang Zhang, Chenwen Zhong, Mohammad Zoladl, Alimuddin Zumla, Stephen S Lim, Theo Vos, Mohsen Naghavi, Michael Brauer, Simon I Hay, Christopher J L Murray, Kyu, H. H., Vongpradith, A., Sirota, S. B., Novotney, A., Troeger, C. E., Doxey, M. C., Bender, R. G., Ledesma, J. R., Biehl, M. H., Albertson, S. B., Frostad, J. J., Burkart, K., Bennitt, F. B., Zhao, J. T., Gardner, W. M., Hagins, H., Bryazka, D., Dominguez, R. -M. V., Abate, S. M., Abdelmasseh, M., Abdoli, A., Abdoli, G., Abedi, A., Abedi, V., Abegaz, T. M., Abidi, H., Aboagye, R. G., Abolhassani, H., Abtew, Y. D., Abubaker Ali, H., Abu-Gharbieh, E., Abu-Zaid, A., Adamu, K., Addo, I. Y., Adegboye, O. A., Adnan, M., Adnani, Q. E. S., Afzal, M. S., Afzal, S., Ahinkorah, B. O., Ahmad, A., Ahmad, A. R., Ahmad, S., Ahmadi, A., Ahmadi, S., Ahmed, H., Ahmed, J. Q., Ahmed Rashid, T., Akbarzadeh-Khiavi, M., Al Hamad, H., Albano, L., Aldeyab, M. A., Alemu, B. M., Alene, K. A., Algammal, A. M., Alhalaiqa, F. A. N., Alhassan, R. K., Ali, B. A., Ali, L., Ali, M. M., Ali, S. S., Alimohamadi, Y., Alipour, V., Al-Jumaily, A., Aljunid, S. M., Almustanyir, S., Al-Raddadi, R. M., Al-Rifai, R. H. 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D, Anbesu, E, Ansar, A, Anyasodor, A, Arabloo, J, Areda, D, Argaw, A, Argaw, Z, Arulappan, J, Aruleba, R, Asemahagn, M, Athari, S, Atlaw, D, Attia, E, Attia, S, Aujayeb, A, Awoke, T, Ayana, T, Ayanore, M, Azadnajafabad, S, Azangou-Khyavy, M, Azari, S, Azari Jafari, A, Badar, M, Badiye, A, Baghcheghi, N, Bagherieh, S, Baig, A, Banach, M, Banerjee, I, Bardhan, M, Barone-Adesi, F, Barqawi, H, Barrow, A, Bashiri, A, Bassat, Q, Batiha, A, Belachew, A, Belete, M, Belgaumi, U, Bhagavathula, A, Bhardwaj, N, Bhardwaj, P, Bhatt, P, Bhojaraja, V, Bhutta, Z, Bhuyan, S, Bijani, A, Bitaraf, S, Bodicha, B, Briko, N, Buonsenso, D, Butt, M, Cai, J, Camargos, P, Camera, L, Chakraborty, P, Chanie, M, Charan, J, Chattu, V, Ching, P, Choi, S, Chong, Y, Choudhari, S, Chowdhury, E, Christopher, D, Chu, D, Cobb, N, Cohen, A, Cruz-Martins, N, Dadras, O, Dagnaw, F, Dai, X, Dandona, L, Dandona, R, Dao, A, Debela, S, Demisse, B, Demisse, F, Demissie, S, Dereje, D, Desai, H, Desta, A, Desye, B, Dhingra, S, Diao, N, Diaz, D, Digesa, L, Doan, L, Dodangeh, M, Dongarwar, D, Dorostkar, F, dos Santos, W, Dsouza, H, Dubljanin, E, Durojaiye, O, Edinur, H, Ehsani-Chimeh, E, Eini, E, Ekholuenetale, M, Ekundayo, T, El Desouky, E, El Sayed, I, El Sayed Zaki, M, Elhadi, M, Elkhapery, A, Emami, A, Engelbert Bain, L, Erkhembayar, R, Etaee, F, Ezati Asar, M, Fagbamigbe, A, Falahi, S, Fallahzadeh, A, Faraj, A, Faraon, E, Fatehizadeh, A, Ferrara, P, Ferrari, A, Fetensa, G, Fischer, F, Flavel, J, Foroutan, M, Gaal, P, Gaidhane, A, Gaihre, S, Galehdar, N, Garcia-Basteiro, A, Garg, T, Gebrehiwot, M, Gebremichael, M, Gela, Y, Gemeda, B, Gessner, B, Getachew, M, Getie, A, Ghamari, S, Ghasemi Nour, M, Ghashghaee, A, Gholamrezanezhad, A, Gholizadeh, A, Ghosh, R, Ghozy, S, Goleij, P, Golitaleb, M, Gorini, G, Goulart, A, Goyomsa, G, Guadie, H, Gudisa, Z, Guled, R, Gupta, S, Gupta, V, Guta, A, Habibzadeh, P, Haj-Mirzaian, A, Halwani, R, Hamidi, S, Hannan, M, Harorani, M, Hasaballah, A, Hasani, H, Hassan, A, Hassani, S, Hassanian-Moghaddam, H, Hassankhani, H, Hayat, K, Heibati, B, Heidari, M, Heyi, D, Hezam, K, Holla, R, Hong, S, Horita, N, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Hoveidamanesh, S, Huang, J, Hussein, N, Iavicoli, I, Ibitoye, S, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Immurana, M, Ismail, N, Iwagami, M, Jaafari, J, Jamshidi, E, Jang, S, Javadi Mamaghani, A, Javaheri, T, Javanmardi, F, Javidnia, J, Jayapal, S, Jayarajah, U, Jayaram, S, Jema, A, Jeong, W, Jonas, J, Joseph, N, Joukar, F, Jozwiak, J, K, V, Kabir, Z, Kacimi, S, Kadashetti, V, Kalankesh, L, Kalhor, R, Kamath, A, Kamble, B, Kandel, H, Kanko, T, Karaye, I, Karch, A, Karkhah, S, Kassa, B, Katoto, P, Kaur, H, Kaur, R, Keikavoosi-Arani, L, Keykhaei, M, Khader, Y, Khajuria, H, Khan, E, Khan, G, Khan, I, Khan, M, Khan, Y, Khatatbeh, M, Khosravifar, M, Khubchandani, J, Kim, M, Kimokoti, R, Kisa, A, Kisa, S, Kissoon, N, Knibbs, L, Kochhar, S, Kompani, F, Koohestani, H, Korshunov, V, Kosen, S, Koul, P, Koyanagi, A, Krishan, K, Kuate Defo, B, Kumar, G, Kurmi, O, Kuttikkattu, A, Lal, D, Lam, J, Landires, I, Ledda, C, Lee, S, Levi, M, Lewycka, S, Liu, G, Liu, W, Lodha, R, Lorenzovici, L, Lotfi, M, Loureiro, J, Madadizadeh, F, Mahmoodpoor, A, Mahmoudi, R, Mahmoudimanesh, M, Majidpoor, J, Makki, A, Malakan Rad, E, Malik, A, Mallhi, T, Manla, Y, Matei, C, Mathioudakis, A, Maude, R, Mehrabi Nasab, E, Melese, A, Memish, Z, Mendoza-Cano, O, Mentis, A, Meretoja, T, Merid, M, Mestrovic, T, Micheletti Gomide Nogueira de Sa, A, Mijena, G, Minh, L, Mir, S, Mirfakhraie, R, Mirmoeeni, S, Mirza, A, Mirza, M, Mirza-Aghazadeh-Attari, M, Misganaw, A, Mohammadi, E, Mohammadi, M, Mohammed, A, Mohammed, S, Mohan, S, Mohseni, M, Moka, N, Mokdad, A, Momtazmanesh, S, Monasta, L, Moniruzzaman, M, Montazeri, F, Moore, C, Moradi, A, Morawska, L, Mosser, J, Mostafavi, E, Motaghinejad, M, Mousavi Isfahani, H, Mousavi-Aghdas, S, Mubarik, S, Murillo-Zamora, E, Mustafa, G, Nair, S, Nair, T, Najafi, H, Naqvi, A, Narasimha Swamy, S, Natto, Z, Nayak, B, Nejadghaderi, S, Nguyen, H, Niazi, R, Nogueira de Sa, A, Nouraei, H, Nowroozi, A, Nunez-Samudio, V, Nzoputam, C, Nzoputam, O, Oancea, B, Ochir, C, Odukoya, O, Okati-Aliabad, H, Okekunle, A, Okonji, O, Olagunju, A, Olufadewa, I, Omar Bali, A, Omer, E, Oren, E, Ota, E, Otstavnov, N, Oulhaj, A, P A, M, Padubidri, J, Pakshir, K, Pakzad, R, Palicz, T, Pandey, A, Pant, S, Pardhan, S, Park, E, Pashazadeh Kan, F, Paudel, R, Pawar, S, Peng, M, Pereira, G, Perna, S, Perumalsamy, N, Petcu, I, Pigott, D, Piracha, Z, Podder, V, Polibin, R, Postma, M, Pourasghari, H, Pourtaheri, N, Qadir, M, Raad, M, Rabiee, M, Rabiee, N, Raeghi, S, Rafiei, A, Rahim, F, Rahimi, M, Rahimi-Movaghar, V, Rahman, A, Rahman, M, Rahmani, A, Rahmanian, V, Ram, P, Ramezanzadeh, K, Rana, J, Ranasinghe, P, Rani, U, Rao, S, Rashedi, S, Rashidi, M, Rasul, A, Ratan, Z, Rawaf, D, Rawaf, S, Rawassizadeh, R, Razeghinia, M, Redwan, E, Reitsma, M, Renzaho, A, Rezaeian, M, Riad, A, Rikhtegar, R, Rodriguez, J, Rogowski, E, Ronfani, L, Rudd, K, Saddik, B, Sadeghi, E, Saeed, U, Safary, A, Safi, S, Sahebazzamani, M, Sahebkar, A, Sakhamuri, S, Salehi, S, Salman, M, Samadi Kafil, H, Samy, A, Santric-Milicevic, M, Sao Jose, B, Sarkhosh, M, Sathian, B, Sawhney, M, Saya, G, Seidu, A, Seylani, A, Shaheen, A, Shaikh, M, Shaker, E, Shamshad, H, Sharew, M, Sharhani, A, Sharifi, A, Sharma, P, Sheidaei, A, Shenoy, S, Shetty, J, Shiferaw, D, Shigematsu, M, Shin, J, Shirzad-Aski, H, Shivakumar, K, Shivalli, S, Shobeiri, P, Simegn, W, Simpson, C, Singh, H, Singh, J, Singh, P, Siwal, S, Skryabin, V, Skryabina, A, Soltani-Zangbar, M, Song, S, Song, Y, Sood, P, Sreeramareddy, C, Steiropoulos, P, Suleman, M, Tabatabaeizadeh, S, Tahamtan, A, Taheri, M, Taheri Soodejani, M, Taki, E, Talaat, I, Tampa, M, Tandukar, S, Tat, N, Tat, V, Tefera, Y, Temesgen, G, Temsah, M, Tesfaye, A, Tesfaye, D, Tessema, B, Thapar, R, Ticoalu, J, Tiyuri, A, Tleyjeh, I, Togtmol, M, Tovani-Palone, M, Tufa, D, Ullah, I, Upadhyay, E, Valadan Tahbaz, S, Valdez, P, Valizadeh, R, Vardavas, C, Vasankari, T, Vo, B, Vu, L, Wagaye, B, Waheed, Y, Wang, Y, Waris, A, West, T, Wickramasinghe, N, Xu, X, Yaghoubi, S, Yahya, G, Yahyazadeh Jabbari, S, Yon, D, Yonemoto, N, Zaman, B, Zandifar, A, Zangiabadian, M, Zar, H, Zare, I, Zareshahrabadi, Z, Zarrintan, A, Zastrozhin, M, Zeng, W, Zhang, M, Zhang, Z, Zhong, C, Zoladl, M, Zumla, A, Lim, S, Vos, T, Naghavi, M, Brauer, M, Hay, S, Murray, C, HUS Comprehensive Cancer Center, and Department of Oncology
Subjects: Adult, Male, Global Health, Time, Global Burden of Disease, SDG 3 - Good Health and Well-being, Risk Factors, RA0421, RA0421 Public health. Hygiene. Preventive Medicine, Humans, Ambient air-quality, Child, Respiratory Tract Infections, Aged, Aged, 80 and over, MCC, Sex Characteristics, Malnutrition, Pyridinolcarbamate, Bayes Theorem, 3rd-DAS, 3142 Public health care science, environmental and occupational health, Infectious Diseases, 3121 General medicine, internal medicine and other clinical medicine, Child, Preschool, Female, Particulate Matter, Quality-Adjusted Life Years, Covid-19, LRI
Abstract: Funding: Bill & Melinda Gates Foundation. Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths. Interpretation: The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting wellbeing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities. Publisher PDF
Published: 2022

6. Awareness of Colorectal Cancer and Associated Factors Among Adult Patients in Jimma, South-West Ethiopia: An Institution-Based Cross-Sectional Study.

Author: Hamza A, Argaw Z, and Gela D
Subjects: Adult, Aged, Awareness, Cross-Sectional Studies, Ethiopia, Female, Humans, Male, Middle Aged, Residence Characteristics, Sociodemographic Factors, Young Adult, Colorectal Neoplasms epidemiology, Health Knowledge, Attitudes, Practice
Abstract: Background: Colorectal cancer (CRC) is the first commonest diagnosed cancer in men and the fourth commonest in women in Ethiopia. Awareness of CRC and associated factors is crucial in the prevention of CRC. However, there have not been studies about the awareness of CRC and associated factors among adult patients in Ethiopia. Therefore, the study aimed to assess the awareness of CRC and associated factors among adult patients in Jimma, South-West Ethiopia, 2020., Methods: This institution-based cross-sectional study design was conducted among 422 adult patients. The study respondents were recruited by a systematic random sampling method. The Cancer Awareness Measure questions were used to measure awareness of CRC of adult patients. Descriptive and logistic regression analyses were conducted., Results: More than half (57.6%) of respondents had low-level awareness of CRC. Respondents who were females (adjusted odds ratio [AOR] = 1.86; 95% CI: 1.26, 2.75), who are residing in urban areas (AOR = .45; 95% CI: .30, .67), who had a monthly income of 3000 Ethiopian Birr and above (AOR = 4.72; 95% CI: 3.11, 7.15), who heard about CRC (AOR = 4.48; 95% CI: 2.90, 6.93), who get information through social media about CRC (AOR = 2.51; 95% CI: 1.18, 5.37), and who had a family history of CRC (AOR = 3.27; 95% CI: 1.45, 7.36) had a high level of awareness of CRC, while those who cannot read and write (AOR = 2.83; 95% CI: 1.49, 5.37) and learn elementary school (AOR = 2.12; 95% CI: 1.15, 3.93) had a low level of awareness of CRC., Conclusion: This study indicated that awareness of CRC of adult patients was inadequate. Adult patients' gender, residency, level of education, monthly income, heard about CRC, sources of information about CRC, and a family history of CRC were found to be independent predictors of the awareness of CRC. Therefore, there is a need for health education and awareness campaigns for promoting awareness of CRC of adult patients, and the government should develop policy on CRC prevention and screening program.
Published: 2021
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7. Practice of and associated factors regarding prevention of surgical site infection among nurses working in the surgical units of public hospitals in Addis Ababa city, Ethiopia: A cross-sectional study.

Author: Mengesha A, Tewfik N, Argaw Z, Beletew B, and Wudu M
Subjects: Cross-Sectional Studies, Ethiopia, Hospitals, Public, Hospitals, Urban, Surveys and Questionnaires, Attitude of Health Personnel, Cross Infection prevention & control, Education, Nursing methods, Health Knowledge, Attitudes, Practice, Nurses statistics & numerical data, Surgical Wound Infection prevention & control
Abstract: Background: Surgical site infections are one of the commonest types of healthcare-associated infections. Up to 60% of these infections are estimated to be preventable by using evidence-based guidelines. As a front line caregiver, nurses are responsible for the majority of preventive activities. Hence, the enhanced practical skill of nurses is an essential component in preventive actions., Objective: The aim of this study was to assess the practice of nurses and identify factors associated with it regarding prevention of surgical site infections in Addis Ababa city public hospitals., Methods: An institution-based cross-sectional study was carried out from March 01-30, 2018. An adapted and pretested, self-administered questionnaire was utilized as a data collection tool. A stratified random sampling technique was employed by considering the level of hospitals as a stratum. Data were entered into a computer using Epi-data 3.1 statistical package. Then, it was exported to SPSS Version 23 for further analysis. Descriptive statistics were computed for the study variables. Bivariate regression analysis was also run to assess the association between independent variables and the level of nurse's practice. To see the relative effect of independent variables on the nurse's practice, a multivariable regression analysis was carried out., Result: A total of 409 nurses returned the questionnaire with a response rate of 98%. Majority (60.4%) of the participants were females and 84.1% were BSc holders. Less than half, (48.9%) of the participants were found to have good practice regarding prevention of surgical site infection. Being male, having more work experience, higher educational level and using available infection prevention guidelines were significantly associated with practice at p <0.05., Conclusion: More than half of the participants have inadequate practice regarding prevention of surgical site infection. Training nurses, making surgical site infection prevention guidelines easily accessible and ensuring possessed knowledge by nurses is potent enough and can be translated into desirable actions are recommended., Competing Interests: The authors have declared that no competing interests exist.
Published: 2020
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8. Survival status and associated factors of death among cervical cancer patients attending at Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia: a retrospective cohort study.

Author: Wassie M, Argaw Z, Tsige Y, Abebe M, and Kisa S
Subjects: Adult, Ethiopia epidemiology, Female, Humans, Middle Aged, Retrospective Studies, Uterine Cervical Neoplasms epidemiology, Uterine Cervical Neoplasms therapy, Uterine Cervical Neoplasms mortality
Abstract: Background: Cervical cancer is a cancer of uterine cervix caused mostly by sexually-acquired infection called Human papillomavirus (HPV. In developing region of the globe, fewer than 50% of women with cervical malignancy survive more than 5 years. Therefore, the objective of this study was to assess survival status and associated factors of death among cervical cancer patients attending at Tikur Anbesa Specialized Hospital (TASH), Ethiopia., Methods: Facility based retrospective cohort study was conducted from March to April 2019 at Tikur Anbesa Specialized Hospital oncology center. Data was collected from patient's chart using pre-tested and structured checklist prepared in English and analyzed using STATA14.2. Cox regression model was used to identify Variables that affected survival., Result: The overall survival rate was 38.62% at 5 years. There were a significance differences in survival experience between categories of stage of cervical cancer, age of patients, comorbidity, substance use, base line anemia and treatment modalities. Being stage IV [AHR = 11.76; 95% CI (4.02-34.4)],being advanced age [AHR = 5.99; 95% CI (2.1-17.08)], being comorbid [AHR = 1.58; 95%CI(1.14-2.19)], using substance [AHR = 1.56;95% CI(1.09-2.22)] and being anemic [AHR = 1.6;95% CI(1.11-2.36)] increased the risk of death., Conclusion: The overall survival rate was lower than high- and middle-income countries and Significant factors of death after diagnosis of cervical cancer were; advanced FIGO stage, base line anemia, comorbidity, substance use, advanced age and treatment modality. Authors recommend that it is better to expand cervical cancer early screening programs and treatment facilities, strengthen awareness in collaboration with public medias about cervical cancer prevention, screening and treatment options.
Published: 2019
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9. Health-related quality of life of patients with diagnosed type 2 diabetes in Felege Hiwot Referral Hospital, North West Ethiopia: a cross-sectional study.

Author: Reba K, Argaw Z, Walle B, and Gutema H
Subjects: Adult, Cross-Sectional Studies, Ethiopia, Female, Humans, Male, Middle Aged, Referral and Consultation, Surveys and Questionnaires, Diabetes Mellitus, Type 2 complications, Quality of Life
Abstract: Objective: Diabetes mellitus is a chronic non-communicable disease with considerable impact on health status and quality of life. It has a profound effect on quality of life in terms of social and psychological as well as physical well-being. This study was conducted to assess health related quality of life among patients with diagnosed type 2 diabetes., Result: A cross-sectional study design was conducted from April to May, 2015. World Health Organization quality of life-BREF tool was used for collecting the data. A total of 344 patients with diagnosed type 2 diabetes were involved in the study. The overall health related quality of life mean score of the study participants was 52.6 ± 12.1 SD. Social domain has higher mean score (57.8 ± 14.8 SD). Educational status, marital status, occupation, duration of the diabetes and diabetes related complications had statistically significant association with health-related quality of life. An intervention that give special attention to the breaking of the cycle of low occupational status and literacy; and which encourage patients with type 2 DM to have good control of their diabetes and prevent complication should be implemented to improve their quality of life.
Published: 2018
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10. Nurses' attitude and perceived barriers to pressure ulcer prevention.

Author: Etafa W, Argaw Z, Gemechu E, and Melese B
Abstract: Background: The presence or absence of pressure ulcers has been generally regarded as a performance measure of quality nursing care and overall patient health. The aim of this study- wasto explorenurses' attitude about pressure ulcer prevention'and to identify staff nurses' perceived barriers to pressure ulcer prevention public hospitals in Addis Ababa, Ethiopia., Methods: A self-reported multi-center institutional based cross sectional study design was employed to collect data from staff nurses ( N = 222) working in six (6) selected public hospitals in Addis Ababa, from April 01-28/2015., Results: Majority of the nurses had ( n = 116, 52.2%) negative attitude towards pressure ulcer prevention. The mean scores of the test for all participants was 3.09out of 11(SD =0.92, range = 1-5). Similarly, the study revealed several barriers need to be resolved to put in to practice the strategies of pressure ulcer prevention; Heavy workload and inadequate staff (lack of tie) (83.1%), shortage of resources/equipment (67.7%) and inadequate training (63.2%) were among the major barriers identified in the study., Conclusions: The study finding suggests that Addis Ababa nurses have negative attitude to pressure ulcer prevention. Also several barriers exist for implementing pressure ulcer prevention protocols in public hospitals in Addis Ababa, Ethiopia. Suggestion for improving this situation is attractive., Competing Interests: Initially ethical clearance was obtained from Addis Ababa University, College of Health Sciences, Department of Nursing and Midwifery Research Review Ethical Committee(Protocol number was 18/Nurse and approved on 27/03/150), and Addis Ababa Regional Health Bureau Ethical Clearance Committee for four hospitals includedin the study (Yekatit 12 Medical College, ZewdituMemoriall Hospital, Tirunesh Beijing Hospital, Menilik II Hospital and RasDesta Memorial Hospital)(reference number: A.A.H/5973/227 and approved on 24/04/2015) to obtain participants in each hospitals. The sixth hospital is teaching hospital (Black Lion Hospital) administered by Addis Ababa University. These findings were part of a research titled “An assessment Nurses’ knowledge, attitude and practice towards pressure ulcer prevention in admitted patients in Public referral hospitals in Addis Ababa. Permissions to obtain participants secured from each hospital medical directors, matrons and head nurses for the research to be undertaken at each hospital. The anonymity of the participants was respected. The names of the participants were not mentioned to keep the confidentiality. A signed written consent was obtained from participants before participation.Not applicable.This manuscript maintains no competing financial interest declaration from any person or organization, or non-financial competing interests such as political, personal, religious, ideological, academic, intellectual, commercial or any other.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Published: 2018
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1. Health Related Quality of Life and Associated Factors Among Adult Patients with Rheumatic Heart Disease Patients in Ethiopia

2. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

3. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

4. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

5. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

6. Awareness of Colorectal Cancer and Associated Factors Among Adult Patients in Jimma, South-West Ethiopia: An Institution-Based Cross-Sectional Study.

7. Practice of and associated factors regarding prevention of surgical site infection among nurses working in the surgical units of public hospitals in Addis Ababa city, Ethiopia: A cross-sectional study.

8. Survival status and associated factors of death among cervical cancer patients attending at Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia: a retrospective cohort study.

9. Health-related quality of life of patients with diagnosed type 2 diabetes in Felege Hiwot Referral Hospital, North West Ethiopia: a cross-sectional study.

10. Nurses' attitude and perceived barriers to pressure ulcer prevention.

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