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4. Association of SARS-CoV-2 infection with neurological impairments in pediatric population: A systematic review

Author

Kwan, Angela T.H., Portnoff, Jacob S., Al-Kassimi, Khaled, Singh, Gurkaran, Hanafimosalman, Mehrshad, Tesla, Marija, Gharibi, Nima, Ni, Tiffany, Guo, Ziji, Sonfack, Davaine J.N., Martyniuk, Julia, Arfaie, Saman, Mashayekhi, Mohammad Sadegh, Mofatteh, Mohammad, Jeremian, Richie, Ho, Kevin, Moscote-Salazar, Luis Rafael, Lee, Ángel, Jawad, Muhammad Youshay, Ceban, Felicia, Teopiz, Kayla M., Mansur, Rodrigo B., Ho, Roger, Rosenblat, Joshua D., Cao, Bing, Rhee, Taeho Greg, and McIntyre, Roger S.

Published
2024
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5. Long-term full-scale intelligent quotient outcomes following pediatric and childhood epilepsy surgery: A systematic review and meta-analysis

Author

Arfaie, Saman, Amin, Pouya, Kwan, Angela T.H., Solgi, Arad, Sarabi, Ali, Hakak-Zargar, Benyamin, Brunette-Clément, Tristan, Pushenko, Denys, Mir-Moghtadaei, Kamran, Mashayekhi, Mohammad Sadegh, Mofatteh, Mohammad, Honarvar, Faraz, Ren, Lily Yuxi, Noiseux-Lush, Camille, Azizi, Zahra, Pearl, Phillip Lawrence, Baldeweg, Torsten, Weil, Alexander G, and Fallah, Aria

Published
2023
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6. Systemic therapy for brain metastases

Author

Rick, Jonathan W, Shahin, Maryam, Chandra, Ankush, Dalle Ore, Cecilia, Yue, John K, Nguyen, Alan, Yagnik, Garima, Sagar, Soumya, Arfaie, Saman, and Aghi, Manish K

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Breast Cancer, Neurosciences, Rare Diseases, Brain Cancer, Lung, Brain Disorders, Cancer, Brain Neoplasms, Breast Neoplasms, Humans, Lung Neoplasms, Melanoma, Systemic therapy, Metastasis, Lung cancer, Breast cancer, Cardiorespiratory Medicine and Haematology, Oncology & Carcinogenesis, Cardiovascular medicine and haematology, Oncology and carcinogenesis
Abstract

Metastases from cells outside of the central nervous system are the most common cancer found in the brain and are commonly associated with poor prognosis. Although cancer treatment is improving overall, central nervous system metastases are becoming more prevalent and require finesse to properly treat. Physicians must consider the biology of the primary tumor and the complex neurological environment that the metastasis resides in. This can be further complicated by the fact that the practice of cancer management is constantly evolving and therapy that works outside of the blood-brain barrier may not be effective inside of it. Therefore, this review seeks to update the reader on recent advancements made on the three most common sources of brain metastases: lung cancer, breast cancer, and melanoma. Each of these malignancies has been the subject of intriguing and novel avenues of therapy which are reviewed here.

Published
2019

8. Anxiety and Depression in Pediatric-Onset Traumatic Spinal Cord Injury: A Systematic Review

Author

Mofatteh, Mohammad, primary, Mashayekhi, Mohammad Sadegh, additional, Arfaie, Saman, additional, Chen, Yimin, additional, Malhotra, Armaan K., additional, Skandalakis, Georgios P., additional, Alvi, Mohammed Ali, additional, Afshari, Fardad T., additional, Meshkat, Shakila, additional, Lin, Famu, additional, Abdulla, Ebtesam, additional, Anand, Ayush, additional, Liao, Xuxing, additional, McIntyre, Roger S., additional, Santaguida, Carlo, additional, Weber, Michael H., additional, and Fehlings, Michael G., additional

Published
2023
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9. Association of SARS-CoV-2 infection with neurological impairments in pediatric population: A systematic review

Author

Kwan, Angela T.H., primary, Al-Kassimi, Khaled, additional, Portnoff, Jacob S., additional, Singh, Gurkaran, additional, Hanafimosalman, Mehrshad, additional, Tesla, Marija, additional, Gharibi, Nima, additional, Ni, Tiffany, additional, Guo, Ziji, additional, Sonfack, Davaine J.N., additional, Martyniuk, Julia, additional, Arfaie, Saman, additional, Mashayekhi, Mohammad Sadegh, additional, Mofatteh, Mohammad, additional, Jeremian, Richie, additional, Ho, Kevin, additional, Moscote-Salazar, Luis Rafael, additional, Lee, Ángel, additional, Jawad, Muhammad Youshay, additional, Ceban, Felicia, additional, Teopiz, Kayla M., additional, Mansur, Rodrigo B., additional, Ho, Roger, additional, Rosenblat, Joshua D., additional, Cao, Bing, additional, Rhee, Taeho Greg, additional, and McIntyre, Roger S., additional

Published
2023
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10. The evolution of randomized controlled trials in Alzheimer's disease: A systematic review and meta-analysis

Author

Kwan, Angela, primary, Therriault, Joseph, additional, Aumont, Etienne, additional, Woo, Marcel, additional, Arfaie, Saman, additional, Servaes, Stijn, additional, Tissot, Cécile, additional, Rahmouni, Nesrine, additional, Macedo, Arthur C., additional, Vitali, Paolo, additional, Soucy, Jean-Paul, additional, Pascoal, Tharick A., additional, Gauthier, Serge, additional, and Rosa-Neto, Pedro, additional

Published
2023
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11. Association of SARS-COV-2 infection with neurological symptoms and neuroimaging manifestations in the pediatric population: A systematic review

Author

Hanafimosalman, Mehrshad, primary, Kwan, Angela, additional, Al-Kassim, Khaled, additional, Portnoff, Jacob, additional, Tesla, Marija, additional, Gharibi, Nima, additional, Ni, Tiffany, additional, Sonfac, Davaine, additional, Martyniuk, Julia, additional, Arfaie, Saman, additional, and Mcintyre, Roger, additional

Published
2023
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12. ChatGPT and neurosurgical education: A crossroads of innovation and opportunity

Author

Arfaie, Saman, Sadegh Mashayekhi, Mohammad, Mofatteh, Mohammad, Ma, Crystal, Ruan, Richard, MacLean, Mark A., Far, Rena, Saini, Jasleen, Harmsen, Irene E., Duda, Taylor, Gomez, Alwyn, Rebchuk, Alexander D., Pingbei Wang, Alick, Rasiah, Neilen, Guo, Eddie, Fazlollahi, Ali M., Rose Swan, Emma, Amin, Pouya, Mohammed, Safraz, Atkinson, Jeffrey D., Del Maestro, Rolando F., Girgis, Fady, Kumar, Ashish, and Das, Sunit

Published
2024
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14. Suicidal Ideation and Attempts in Brain Tumor Patients and Survivors: A Systematic Review

Author

Mofatteh, Mohammad, primary, Mashayekhi, Mohammad Sadegh, additional, Arfaie, Saman, additional, Chen, Yimin, additional, Malhotra, Armaan K, additional, Alvi, Mohammed Ali, additional, Sader, Nicholas, additional, Antonick, Violet, additional, Fatehi Hassanabad, Mostafa, additional, Mansouri, Alireza, additional, Das, Sunit, additional, Liao, Xuxing, additional, McIntyre, Roger S, additional, Del Maestro, Rolando, additional, Turecki, Gustavo, additional, Cohen-Gadol, Aaron A, additional, Zadeh, Gelareh, additional, and Ashkan, Keyoumars, additional

Published
2023
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15. Medial Temporal Tau Predicts Memory Decline in Cognitively Unimpaired Elderly (P5-6.011)

Author

Kwan, Angela, primary, Arfaie, Saman, additional, Therriault, Joseph, additional, Azizi, Zahra, additional, Lussier, Firoza, additional, Tissot, Cecile, additional, Chamoun, Mira, additional, Bezgin, Gleb, additional, Servaes, Stijn, additional, Stevenon, Jenna, additional, Rahmouni, Nesrine, additional, Pallen, Vanessa, additional, and Rosa-Neto, Pedro, additional

Published
2023
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16. Awake Craniotomy During Pregnancy: A Systematic Review of The Published Literature

Author

Mofatteh, Mohammad, primary, Mashayekhi, Mohammad Sadegh, additional, Arfaie, Saman, additional, Wei, Hongquan, additional, Kazerouni, Arshia, additional, Skandalakis, Georgios, additional, Pour-Rashidi, Ahmad, additional, Baiad, Abed, additional, Elkaim, Lior, additional, Lam, Jack, additional, Palmisciano, Paolo, additional, Su, Xiumei, additional, Liao, Xuxing, additional, Backman, Steven, additional, Das, Sunit, additional, Ashkan, Keyoumars, additional, and Cohen-Gadol, Aaron, additional

Published
2023
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17. Neuroanatomical Predictors of Alcohol Consumption in Adolescents via in vivo Structural Imaging: A Systematic Review of Longitudinal Studies

Author

Honarvar, Faraz, primary, Arfaie, Saman, additional, Edalati, Hanie, additional, Ghasroddashti, Arashk, additional, Solgi, Arad, additional, Mashayekhi, Mohammad Sadegh, additional, Mofatteh, Mohammad, additional, Ren, Lily Yuxi, additional, Kwan, Angela Tian Hui, additional, and Keramatian, Kamyar, additional

Published
2023
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18. Association of SARS-CoV-2 Infection with Neurological Symptoms and Neuroimaging Manifestations in the Pediatric Population: A Systematic Review

Author

Kwan, Angela T.H., primary, Al-Kassimi, Khaled, additional, Portnoff, Jacob S., additional, Tesla, Marija, additional, Hanafimosalman, Mehrshad, additional, Gharibi, Nima, additional, Ni, Tiffany, additional, Sonfack, Davaine J.N., additional, Martyniuk, Julia, additional, Arfaie, Saman, additional, Mashayekhi, Mohammad Sadegh, additional, Mofatteh, Mohammad, additional, Jeremian, Richie, additional, Moscote-Salazar, Luis Rafael, additional, Lee, Ángel, additional, Jawad, Muhammad Youshay, additional, Guo, Ziji, additional, Ceban, Felicia, additional, Teopiz, Kayla M., additional, Mansur, Rodrigo B., additional, Ho, Roger, additional, Rosenblat, Joshua D., additional, Cao, Bing, additional, Rhee, Taeho Greg, additional, and McIntyre, Roger S., additional

Published
2023
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19. Awake Craniotomy in Africa: A Scoping Review of Literature and Proposed Solutions to Tackle Challenges.

Author

Mofatteh, Mohammad, Mashayekhi, Mohammad Sadegh, Arfaie, Saman, Adeleye, Amos Olufemi, Jolayemi, Edward Olaoluwa, Ghomsi, Nathalie C., Shlobin, Nathan A., Morsy, Ahmed A., Esene, Ignatius N., Laeke, Tsegazeab, Awad, Ahmed K., Labuschagne, Jason J., Ruan, Richard, Abebe, Yared Nigusie, Jabang, John Nute, Okunlola, Abiodun Idowu, Barrie, Umaru, Lekuya, Hervé Monka, Marcel, Ehanga Idi, and Kabulo, Kantenga Dieu Merci

Published
2023
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20. Long-Term Full-Scale Intelligent Quotient Outcomes Following Pediatric and Childhood Epilepsy Surgery: A Systematic Review and Meta-Analysis

Author

Arfaie, Saman, primary, Amin, Pouya, additional, Kwan, Angela T.H., additional, Solgi, Arad, additional, Sarabi, Ali, additional, Hakak-Zargar, Benyamin, additional, Brunette-Clément, Tristan, additional, Pushenko, Denys, additional, Mir-Moghtadaei, Kamran, additional, Mashayekhi, Mohammad Sadegh, additional, Mofatteh, Mohammad, additional, Honarvar, Faraz, additional, Ren, Lily Yuxi, additional, Noiseux-Lush, Camille, additional, Azizi, Zahra, additional, Pearl, Phillip L., additional, Baldeweg, Torsten, additional, Weil, Alexander, additional, and Fallah, Aria, additional

Published
2023
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23. Medial temporal tau predicts memory decline in cognitively unimpaired elderly

Author

Kwan, Angela T H, primary, Arfaie, Saman, additional, Therriault, Joseph, additional, Azizi, Zahra, additional, Lussier, Firoza Z, additional, Tissot, Cecile, additional, Chamoun, Mira, additional, Bezgin, Gleb, additional, Servaes, Stijn, additional, Stevenon, Jenna, additional, Rahmouni, Nesrine, additional, Pallen, Vanessa, additional, Gauthier, Serge, additional, and Rosa-Neto, Pedro, additional

Published
2022
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29. The Inception of the Canadian Medical Student Interest Group in Neurosurgery (CaMSIGN): A Student-Led Platform Dedicated to Neurosurgical Education, Research, Mentorship, and Advocacy

Author

Arfaie, Saman, primary, Laghaei Farimani, Pedram, additional, Mashayekhi, Mohammad Sadegh, additional, Hakak-Zargar, Benyamin, additional, Fatehi Hassanabad, Mostafa, additional, Smith-Forrester, Jenna, additional, Sader, Nicholas, additional, Hodaie, Mojgan, additional, Del Maestro, Rolando, additional, and Das, Sunit, additional

Published
2022
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33. Canada's Education System: Policies & Challenges During the COVID-19 Pandemic. An Interview With Dr. Charles Ungerleider.

Author

Arfaie, Saman, Glinos, Peter, and Honarvar, Faraz

Subjects
EXPERIENTIAL learning, COVID-19 pandemic, SCHOOL closings, ONLINE education, SOCIAL cohesion, FOREIGN students
Abstract

This work is a scholarly interview conducted with Dr. Charles Ungerleider on the effects of COVID-19 in Canada. The discussion explores the various aspects of the pandemic's impact on Canadian education, such as: the effects of school closures; Canada's lack of a federal ministry of education; the burnout faced by educators resulting from the sudden shift to online education; the obstacles in educating international students; the reduction of experiential learning in post-secondary schools; the media's portrayal and politicization of pandemic school closures; the forced integration of virtual learning technology; the disproportionately deleterious repercussions of the pandemic education on the marginalized; and the need for schools in creating social cohesion. [ABSTRACT FROM AUTHOR]

Published
2022
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34. Systemic therapy for brain metastases

Author

Rick, Jonathan W, primary, Shahin, Maryam, additional, Chandra, Ankush, additional, Dalle Ore, Cecilia, additional, Yue, John K., additional, Nguyen, Alan, additional, Yagnik, Garima, additional, Sagar, Soumya, additional, Arfaie, Saman, additional, and Aghi, Manish K., additional

Published
2019
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35. GBA1and The Immune System: A Potential Role in Parkinson’s Disease?

Author

Al-Azzawi, Zaid A.M., Arfaie, Saman, and Gan-Or, Ziv

Abstract

It is clear that the immune system and inflammation have a role in Parkinson’s disease (PD), including sporadic PD and some genetic forms such as LRRK2-associated PD. One of the most important genes associated with PD is GBA1, as mutations in this gene are found in 5–20% of PD patients in different populations worldwide. Biallelic mutations in GBA1may cause Gaucher disease, a lysosomal storage disorder with involvement of the immune system, and other lines of evidence link GBA1to the immune system and inflammation. In this review, we discuss these different pieces of evidence and whether the interplay between GBA1and the immune system may have a role in PD.

Published
2022
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36. TMIC-46. FIBROBLAST-PRODUCED EDA FIBRONECTIN IN THE SUBVENTRICULAR ZONE DRIVES GLIOBLASTOMA PATHOGENESIS

Author

Rick, Jonathan, primary, Nguyen, Alan, additional, Chandra, Ankush, additional, Yagnik, Garima, additional, Lau, Darryl, additional, Chuntova, Polly, additional, Ordaz, Angel, additional, Dayani, Fara, additional, Garcia, Joseph, additional, Sagar, Soumya, additional, Arfaie, Saman, additional, Ore, Cecilia Dalle, additional, and Aghi, Manish, additional

Published
2018
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39. Association of SARS-CoV-2 Infection with Neurological Symptoms and Neuroimaging Manifestations in the Pediatric Population: A Systematic Review.

Author

Kwan ATH, Al-Kassimi K, Portnoff JS, Tesla M, Hanafimosalman M, Gharibi N, Ni T, Sonfack DJN, Martyniuk J, Arfaie S, Mashayekhi MS, Mofatteh M, Jeremian R, Moscote-Salazar LR, Lee Á, Jawad MY, Guo Z, Ceban F, Teopiz KM, Mansur RB, Ho R, Rosenblat JD, Cao B, Rhee TG, and McIntyre RS

Abstract

Background: Neurological manifestations have been widely reported in adults with COVID-19, yet the extent of involvement among the pediatric population is currently poorly characterized. The objective of our systematic review is to evaluate the association of SARS-CoV-2 infection with neurological symptoms and neuroimaging manifestations in the pediatric population., Methods: A literature search of Cochrane Library; EBSCO CINAHL; Global Index Medicus; OVID AMED, Embase, Medline, PsychINFO; and Scopus was conducted in accordance with the Peer Review of Electronic Search Strategies form (October 1, 2019 to March 15, 2022). Studies were included if they reported (1) COVID-19-associated neurological symptoms and neuroimaging manifestations in individuals aged < 18 years with a confirmed, first SARS-CoV-2 infection and were (2) peer-reviewed. Full-text reviews of 222 retrieved articles were performed, along with subsequent reference searches., Results: A total of 843 nonduplicate records were retrieved. Of the 19 identified studies, there were ten retrospective observational studies, seven case series, one case report, and one prospective cohort study. A total of 6,985 individuals were included, where 12.8% of hospitalized patients experienced neurocognitive impairments: MIS-C (24.2%), neuroinflammation (10.1%), and encephalopathy (8.1%) were the most common disorders; headaches (16.8%) and seizures (3.8%) were the most common symptoms. Based on pediatric-specific cohorts, children experienced more drowsiness (7.3% vs. 1.3%) and muscle weakness (7.3% vs. 6.3%) as opposed to adolescents. Agitation or irritability was observed more in children (7.3%) than infants (1.3%)., Conclusion: Our findings revealed a high prevalence of immune-mediated patterns of disease among COVID-19 positive pediatric patients with neurocognitive abnormalities., Competing Interests: Competing interests: The authors declare no competing interests.

Published
2023
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