90 results on '"Aras Júnior, Roque"'
Search Results
2. A Multifactorial Analysis of Extracranial Carotid Disease: A Comprehensive Approach to Sonographic Criteria
- Author
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Silva, Fernanda Costa Sampaio and Aras Júnior, Roque
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- 2023
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- View/download PDF
3. Overexpression of miR-126-5p in the serum of patients with systemic arterial hypertension is correlated with creatinine and platelets
- Author
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Improta-Caria, Alex Cleber, primary, Nonaka, Carolina Kymie Vasques, additional, Aras, Marcela Gordilho, additional, Nunes, Bianca Almeida, additional, De Sousa, Ricardo Augusto Leoni, additional, Oliveira, Edilamar Menezes, additional, Roever, Leonardo, additional, Souza, Bruno Solano Freitas, additional, and Aras-Júnior, Roque, additional
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- 2024
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- View/download PDF
4. Physical exercise effects on the brain during COVID-19 pandemic: links between mental and cardiovascular health
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De Sousa, Ricardo Augusto Leoni, Improta-Caria, Alex Cleber, Aras-Júnior, Roque, de Oliveira, Edilamar Menezes, Soci, Úrsula Paula Reno, and Cassilhas, Ricardo Cardoso
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- 2021
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5. Effect of hormone therapy on blood pressure and hypertension in postmenopausal women: a systematic review and meta-analysis.
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Campos, Luana Ferreira, de Andrade Costa, Guilherme, Domingues Feitosa, Marina, Ferreira Félix, Iuri, Gabrielli, Ligia, C. Almeida, Maria da Conceição, Aquino, Estela M. L., and Aras Júnior, Roque
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- 2024
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- View/download PDF
6. Effect of hormone therapy on blood pressure and hypertension in postmenopausal women: a systematic review and meta-analysis
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Ferreira Campos, Luana, de Andrade Costa, Guilherme, Domingues Feitosa, Marina, Ferreira Félix, Iuri, Gabrielli, Ligia, C. Almeida, Maria da Conceição, ML Aquino, Estela, and Aras Júnior, Roque
- Abstract
Based on the results of this meta-analysis, the effect of hormone therapy on blood pressure is influenced by the formulation used, especially the type of estrogen.
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- 2024
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- View/download PDF
7. Angiolymphoid Hyperplasia With Temporal Artery Eosinophilia: A Case Report.
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Carvalho Lujan, Ricardo Augusto, de Melo Mascarenhas, Diego Antonio, de Amorim Aquino, Maurício, Costa Menezes, Aline, Pereira de Souza Filho, Marcelo Luis, Costa Sampaio Silva, Fernanda, Godeiro Fernandez, Miguel, Silveira Alves, Carlos Alberto, and Aras Júnior, Roque
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TEMPORAL arteries ,PHYSICAL diagnosis ,IMMUNOHISTOCHEMISTRY ,MAGNETIC resonance imaging ,EOSINOPHILIA - Abstract
Angiolymphoid Hyperplasia with Eosinophilia (ALHE) is a benign vascular proliferative disorder with uncertain etiology and pathogenesis. The aim of this paper is to report a case of ALHE in the temporal artery and discuss the general aspects of this pathology. A 29-year-old female black patient sought the Vascular Surgery Outpatient Service, complaining of bulging in the right temporal region, associated with pain and local discomfort. Physical examination revealed pulsatile bulging in the right temporal region measuring approximately 2.5 × 1.5 cm. Nuclear Magnetic Resonance showed an expansive fusiform lesion in the superficial soft parts of the right temporal region, measuring 2.9 cm in the longest longitudinal axis. Surgical excision proved to be the best therapeutic option for the patient in this case. Histopathological sections showed the proliferation of vessels of different sizes, covered by swollen endothelium, prominent inflammatory infiltrate composed of lymphocytes, plasma cells, eosinophils, and scarce histiocytes. Immunohistochemical analysis of the lesion showed positivity for CD31, corroborating the diagnosis of ALHE. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Stroke Is Associated with Refractory Hypertension among Resistant and Refractory Patients in a Cross-Sectional Study
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Costa, Guilherme de Andrade, Oliveira Filho, Jamary, Ferreira-Campos, Luana, Improta-Caria, Alex Cleber, Macedo, Cristiano, Sarno Filho, Marcelo Vincenzo, Borges, Leonardo Silva Roever, and Aras Júnior, Roque
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Stroke ,Heart Disease Risk Factors ,Hypertension - Abstract
Background Refractory hypertension (RfH) is a severe phenotype of resistant hypertension (RH) linked to higher risk of stroke and other adverse cardiovascular events, but knowledge about it is still lacking. Objectives To evaluate the association between RfH and stroke. Methods We conducted a cross-sectional study in a referral clinic for patients with severe hypertension in the period from 2018 to 2020. RH was defined as uncontrolled blood pressure (BP) despite the use of 3 antihypertensive agents, including a diuretic, or the use of ≥ 4 agents regardless of BP control. RfH was defined as lack of BP control despite use of ≥ 5 antihypertensive agents. Individuals were classified as RfH or RH, and multivariate logistic regression models were constructed to examine the association between RfH and stroke. Results We evaluated a total of 137 patients; 81% were female, and 93,3% were Black or multiracial. The mean age was 64.4 years. Stroke was more prevalent in the RfH group (35.7%), in comparison to the RH group (12.8%) (p value = 0.01). Unadjusted odds ratio (OR) and 95% confidence interval (CI) for factors associated with stroke were RfH (OR 3.77; 95% CI 1.45 to 9.80), systolic BP (OR 1.02; 95% CI 1.002 to 1.04) and diastolic BP (OR 1.03; 95% CI 1.001 to 1.06). Adjusted OR for factors associated with stroke were RfH (OR 3.55; 95% CI 1.02 to 12.42), systolic BP (OR 1.02; 95% CI 0.99 to 1.05) and diastolic BP (OR 1.01; 95% CI 0.96 to 1.06). Conclusion RfH was associated with higher prevalence of stroke. Efforts are required to better understand this association to prevent adverse cardiovascular outcomes in these patients.
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- 2023
9. A Multifactorial Analysis of Extracranial Carotid Disease: A Comprehensive Approach to Sonographic Criteria
- Author
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Silva, Fernanda Costa Sampaio, primary and Aras Júnior, Roque, additional
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- 2022
- Full Text
- View/download PDF
10. MicroRNAs in type 2 diabetes mellitus: potential role of physical exercise
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Improta-Caria, Alex Cleber, primary, De Sousa, Ricardo Augusto Leoni, primary, Roever, Leonardo, primary, Fernandes, Tiago, primary, Oliveira, Edilamar Menezes de, primary, Aras Júnior, Roque, primary, and Souza, Bruno Solano de Freitas, primary
- Published
- 2022
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11. The Impact of COVID-19 on the Cardiovascular System
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Aras Júnior, Roque, Durães, André, Roever, Leonardo, Macedo, Cristiano, Aras, Marcela Gordilho, Nascimento, Luca, Improta-Caria, Alex Cleber, and De Sousa, Ricardo Augusto Leoni
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Coronavirus ,Betacoronavirus ,Infection ,Cardiovascular System - Abstract
SUMMARY The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19), has affected many people in Brazil and worldwide. This disease predominantly affects the organs of the respiratory system, but it also damages the brain, liver, kidneys and especially the heart. In the heart, scientific evidence shows that this virus can damage the coronary arteries, generating microvascular dysfunction, favoring acute myocardial infarction. Furthermore, with the increased expression of pro-inflammatory cytokines, it can lead to myocarditis and cardiac fibrosis, inducing changes in the electrical conduction system of the heart, generating cardiac arrhythmias. All these factors mentioned are protagonists in promoting the increase in the mortality outcome. This outcome may be even higher if the individuals are elderly, or if they have other diseases such as type 2 diabetes mellitus or hypertension, because they may already have cardiomyopathy. In this context, this review focused on the impact that COVID-19 can have on the heart and cardiovascular system and the association of this impact with aging, type 2 diabetes mellitus, cardiac arrhythmias and arterial hypertension
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- 2021
12. MicroRNAs Regulating Renin–Angiotensin–Aldosterone System, Sympathetic Nervous System and Left Ventricular Hypertrophy in Systemic Arterial Hypertension
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Improta-Caria, Alex Cleber, primary, Aras, Marcela Gordilho, additional, Nascimento, Luca, additional, De Sousa, Ricardo Augusto Leoni, additional, Aras-Júnior, Roque, additional, and Souza, Bruno Solano de Freitas, additional
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- 2021
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13. Physical activity for health and use of face masks in the COVID-19 pandemic
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Pitanga, Francisco José Gondim, primary, Brito, Marcus Paulo, additional, Silva, Maguino Santos, additional, Gomes, Jorge Medeiros, additional, Aras Júnior, Roque, additional, Alves, Carlos Fernando de Amorim, additional, and Caria, Alex Cleber Improta, additional
- Published
- 2021
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14. Prognostic power of conventional echocardiography in individuals without history of cardiovascular diseases: A systematic review and meta-analysis
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Fernandes, Luciana Pereira, primary, Barreto, Ana Terra Fonseca, additional, Neto, Mansueto Gomes, additional, Câmara, Edmundo José Nassri, additional, Durães, André Rodrigues, additional, Roever, Leonardo, additional, and Aras-Júnior, Roque, additional
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- 2021
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15. The Impact of COVID-19 on the Cardiovascular System
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Aras Júnior, Roque, primary, Durães, André, additional, Roever, Leonardo, additional, Macedo, Cristiano, additional, Aras, Marcela Gordilho, additional, Nascimento, Luca, additional, Improta-Caria, Alex Cleber, additional, and De Sousa, Ricardo Augusto Leoni, additional
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- 2021
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16. Physical Exercise and Immune System: Perspectives on the COVID-19 pandemic
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Improta-Caria, Alex Cleber, primary, Soci, Úrsula Paula Renó, additional, Pinho, Cristiano Silva, additional, Aras Júnior, Roque, additional, De Sousa, Ricardo Augusto Leoni, additional, and Bessa, Theolis Costa Barbosa, additional
- Published
- 2021
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17. MicroRNAs in type 2 diabetes mellitus: potential role of physical exercise.
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Cleber Improta-Caria, Alex, Leoni De Sousa, Ricardo Augusto, Roever, Leonardo, Fernandes, Tiago, Menezes de Oliveira, Edilamar, Aras Júnior, Roque, de Freitas Souza, Bruno Solano, Improta-Caria, Alex Cleber, De Sousa, Ricardo Augusto Leoni, Oliveira, Edilamar Menezes de, and Souza, Bruno Solano de Freitas
- Abstract
Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disease, and its prevalence has grown worldwide. Several pathophysiological processes contribute to the development, progression and aggravating of the disease, for example, decreased insulin synthesis and secretion, insulin resistance, inflammation, and apoptosis, all these processes are regulated by various epigenetic factors, including microRNAs (miRNAs). MiRNAs are small non-coding RNAs, which are around 20 nucleotides in length and are regulators of gene expression at the post-transcriptional level, have a specific function of inhibiting or degrading a messenger RNA target. Thus, miRNAs modulate the expression of many associated genes with the pathophysiological processes in T2DM. On the other hand, miRNAs are also modulated through physical exercise (PE), which induces a change in their expression pattern during and after exercise. Some scientific evidence shows that PE modulates miRNAs beneficially and improves the signaling pathway of insulin resistance, however, little is known about the function of PE modulating miRNAs associated with the processes of insulin secretion, inflammation, and apoptosis. Thus, the objective of this review is to identify the miRNAs expression pattern in T2DM and compare it with the exercise-induced miRNAs expression pattern, identifying the signaling pathways that these miRNAs are regulating in the processes of insulin secretion, insulin resistance, inflammation, and apoptosis in T2DM, and how PE may have a potential role in modulating these signal transduction pathways, promoting benefits for patients with T2DM. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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18. Modulation of MicroRNAs as a Potential Molecular Mechanism Involved in the Beneficial Actions of Physical Exercise in Alzheimer Disease
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Improta-Caria, Alex Cleber, primary, Nonaka, Carolina Kymie Vasques, additional, Cavalcante, Bruno Raphael Ribeiro, additional, De Sousa, Ricardo Augusto Leoni, additional, Aras Júnior, Roque, additional, and Souza, Bruno Solano de Freitas, additional
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- 2020
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19. The effects of the COVID-19 pandemic on levels of physical fitness
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Pinho, Cristiano Silva, primary, Caria, Alex Cleber Improta, additional, Aras Júnior, Roque, additional, and Pitanga, Francisco José Gondim, additional
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- 2020
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20. Assessment of Right Ventricle Function and Myocardial Fibrosis by Cardiovascular Magnetic Resonance in Patients with Inferior Wall Myocardial Infarction
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Lacerda, Priscila Neri, primary, Almeida, Rafael Fernandes, additional, Pinto, Fernanda Gabriella Figueiredo, additional, Gomes Júnior, Adilson Machado, additional, Santos, Jéssica Mendes, additional, Macêdo, Cristiano Ricardo Bastos de, additional, Fernandes, André Maurício Souza, additional, and Aras Júnior, Roque, additional
- Published
- 2017
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21. Revista Argentina de Cardiología
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Reis, Francisco Borges dos, Fernandes, André Maurício Souza, Andrade, Gustavo M. de, Bitencourt, Almir Galvão Vieira, Neves, Flávia Branco Cerqueira Serra, Franca, Víctor H., Macedo, Cristiano Ricardo Bastos de, Cruz, Cristiano Gonçalves da, Braga, Julio Cesar Vieira, and Aras Júnior, Roque
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Enfermedad de Chagas ,Insuficiencia cardíaca ,Insuficiencia cardíaca diastólica - Abstract
p. 246-250 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-05-13T13:29:36Z No. of bitstreams: 1 1417-15570-1-PB.pdf: 207340 bytes, checksum: 56a41fee5029c0c65d214f0b942072a9 (MD5) Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-07-09T12:11:04Z (GMT) No. of bitstreams: 1 1417-15570-1-PB.pdf: 207340 bytes, checksum: 56a41fee5029c0c65d214f0b942072a9 (MD5) Made available in DSpace on 2014-07-09T12:11:04Z (GMT). No. of bitstreams: 1 1417-15570-1-PB.pdf: 207340 bytes, checksum: 56a41fee5029c0c65d214f0b942072a9 (MD5) Previous issue date: 2013 Introducción: La insuficiencia cardíaca con función sistólica preservada es un síndrome clínico con los mismos signos y síntomas de la insuficiencia cardíaca clásica. La enfermedad de Chagas es una causa importante de insuficiencia cardíaca en América Latina, que se asocia con miocardiopatía dilatada y deterioro progresivo de la función sistólica. No existen estudios previos que hayan evaluado pacientes con insuficiencia cardíaca y función sistólica preservada de una zona endémica en la cual la enfermedad de Chagas es la causa principal de insuficiencia cardíaca. Objetivo: Comparar las características clínicas y la evolución de la insuficiencia cardíaca en pacientes con disfunción sistólica y con función sistólica preservada en una población con alta prevalencia de enfermedad de Chagas. Material y métodos: Se realizó una evaluación prospectiva de los pacientes con diagnóstico clínico de insuficiencia cardíaca que ingresaron a un centro de referencia en Salvador, Bahía (Brasil). Se consideró función sistólica preservada a una fracción de eyección del ventrículo izquierdo mayor del 45% por ecocardiograma. Se realizó seguimiento al año a través de contacto telefónico o entrevista personal en el consultorio de insuficiencia cardíaca. Resultados: Se incluyeron 383 pacientes durante un período de 16 meses; el 52,5% eran hombres y la edad media fue de 54,2 años. La función sistólica estuvo preservada en 138 pacientes (36%). La enfermedad de Chagas fue la principal etiología de ambos tipos de insuficiencia cardíaca (45,3% con disfunción sistólica y 44,2% con función sistólica preservada). El 93,5% (358) de los pacientes completaron un año de seguimiento. Los pacientes con enfermedad de Chagas y función sistólica preservada tuvieron menor mortalidad que los pacientes con disfunción sistólica (10% vs. 23,6%; p = 0,039). En los pacientes sin enfermedad de Chagas y función sistólica preservada, la mortalidad fue similar a la de aquellos con disfunción sistólica (10,4% vs. 15,8%; p = 0,307). Conclusiones: La función sistólica preservada fue muy frecuente en nuestra población. La enfermedad de Chagas es la principal etiología de insuficiencia cardíaca independientemente de la fracción de eyección del ventrículo izquierdo. Los pacientes con enfermedad de Chagas y función sistólica preservada tienen mejor pronóstico que aquellos con disfunción sistólica, probablemente porque se encuentran en la fase inicial del compromiso cardíaco.
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- 2013
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22. Jornal Brasileiro de Patologia e Medicina Laboratorial
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Oliveira, Rogério Jorge Barbosa de, Santos, Ana Paula Caires dos, Santos Junior, Lázaro Silveira, Vieira, Marcos Soares, Aras Júnior, Roque, Couto, Fábio David, and Couto, Ricardo David
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Paraoxonase ,Lipoproteins ,Atherosclerosis ,Echocardiography vascular - Abstract
p.18-24 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-17T13:15:59Z No. of bitstreams: 1 Rogério Jorge Barbosa de Oliveira.pdf: 167540 bytes, checksum: d50995c35ae00f50bcfd54a8af8e854a (MD5) Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-04T15:36:58Z (GMT) No. of bitstreams: 1 Rogério Jorge Barbosa de Oliveira.pdf: 167540 bytes, checksum: d50995c35ae00f50bcfd54a8af8e854a (MD5) Made available in DSpace on 2015-05-04T15:36:58Z (GMT). No. of bitstreams: 1 Rogério Jorge Barbosa de Oliveira.pdf: 167540 bytes, checksum: d50995c35ae00f50bcfd54a8af8e854a (MD5) Previous issue date: 2013 INTRODUCTION: Atherosclerosis and correlated cardiovascular problems, whose mechanical and physiological disorders cause thickening and hardening of blood vessels, are among the main causes of death worldwide. OBJECTIVE: To assess plasma concentrations of biomarkers from the lipid metabolism and carotid doppler sonography results by correlating them with atherogenic carotid disease. METHODS: the study comprised 66 patients aged 57.5 ± 15.5 years (20-77), from which 63% were female. Serum markers and doppler sonography images were used to evaluate the association with atherogenic carotid disease (ACD). RESULTS: There was a higher prevalence of ACD among females (33% vs. 15%), age range 56-65, showing a relative risk (RR) of 1.56 among females (p < 0.002; Fisher, Katz). Concerning high density lipoprotein cholesterol (HDL-C) and carotid stenosis classification, North American Symptomatic Carotid Endarterectomy Trial (NASCET), 76% of patients showed HDL-C within the protection range, from which 31 individuals presented level I (normal). 81% of them showed HDL-C > 40 mg/dl and 19% had HDL-C ≥ 40 mg/dl. The prevalence of HDL-C > 40 mg/dl at levels II, III and IV was considerable. There was no difference in HDL-C among the groups (p = 0.4910; unpaired t test). Furthermore, there was no difference in paraoxonase (PON1) activity when stratified to HDL-C > and < 40 mg/dl (p > 0.05). CONCLUSION: The female group displayed higher ACD prevalence at 56-65 age range, with RR of 1.56 times higher. These findings substantiate the importance of analyzing this group and age range carefully, inasmuch as the absence of hormonal protection may increase ACD risk and ultimately influence HDL antioxidant activity due to its direct action on PON1. Triglycerides (TG)/HDL-C ratio indicates cardiovascular risk and impaired reverse cholesterol transport.
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- 2013
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23. Impacto do perfil socioeconômico na escolha da prótese valvar em cirurgia cardíaca
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Fernandes, André Maurício S., Bitencourt, Larissa Santana, Lessa, Igor Nogueira, Viana, Agnaldo, Pereira, Felipe, Bastos, Gabriel, Macedo, Cristiano Ricardo Bastos de, and Aras Júnior, Roque
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Doenças das valvas cardíacas ,Fatores socioeconômicos ,Heart valve diseases ,Implante de prótese ,Prosthesis implantation ,Socioeconomic factors - Abstract
INTRODUÇÃO: A doença cardíaca valvar é um grave problema de saúde pública, mais frequente em países em desenvolvimento, acometendo indivíduos em idade laboralmente produtiva. OBJETIVO: Avaliar o perfil socioeconômico e epidemiológico dos pacientes submetidos a cirurgia valvar e a sua relação com os tipos de próteses utilizadas em um centro de referência público de Salvador, BA, Brasil. MÉTODOS: Estudo de corte transversal descritivo de prevalência, no qual foram analisados retrospectivamente idade, sexo, procedência, tipo de valvopatia, cirurgia a qual o paciente foi submetido e o tipo de prótese utilizada em casos de trocas, em centro de referência público de cardiologia. RESULTADOS: Foram revisados 366 prontuários, de todos os pacientes submetidos a cirurgia de valva cardíaca, de janeiro de 2007 a dezembro de 2009. Em relação ao sexo, 52% dos pacientes eram do sexo feminino. A idade média ± DP foi de 41,70 ± 17,85 anos. Dentre os pacientes, 37,7% eram procedentes da capital e 62,3%, do interior do estado da Bahia (Brasil). A troca valvar foi realizada em 73% dos pacientes, enquanto que 7,38% realizaram plastia valvar e 18,3% realizaram tanto plastia quanto troca. Dos pacientes que realizaram troca valvar, 70% receberam bioprótese e 30% do tipo metálica, com predominância do uso bioprótese nas faixas etárias jovens (P
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- 2012
24. PLoS ONE
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Matta, José Alberto Martins da, Aras Júnior, Roque, Macedo, Cristiano Ricardo Bastos de, Cruz, Cristiano Gonçalves da, and Martins Netto, Eduardo
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p. 1-7 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-12T16:36:07Z No. of bitstreams: 1 Ronaldo L. Oliveira.pdf: 700877 bytes, checksum: b4bfdf34c0cb2047c8f1ffc8d0aadacb (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-08-13T16:11:16Z (GMT) No. of bitstreams: 1 Ronaldo L. Oliveira.pdf: 700877 bytes, checksum: b4bfdf34c0cb2047c8f1ffc8d0aadacb (MD5) Made available in DSpace on 2014-08-13T16:11:16Z (GMT). No. of bitstreams: 1 Ronaldo L. Oliveira.pdf: 700877 bytes, checksum: b4bfdf34c0cb2047c8f1ffc8d0aadacb (MD5) Previous issue date: 2012-04 Background Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease. We studied stroke correlates in cardiomyopathy patients with focus on the chagasic etiology. Methodology/Principal Findings We performed a cross-sectional review of medical records of 790 patients with a cardiomyopathy. Patients with chagasic (329) and non-chagasic (461) cardiomyopathies were compared. There were 108 stroke cases, significantly more frequent in the Chagas group (17.3% versus 11.1%; p
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- 2012
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25. Journal of Cardiothoracic Surgery
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Araújo, Carlos José Soares de, Gonçalves, Fernanda Souza, Bittencourt, Hugo Souza, Rodrigues Junior, Erenaldo de Souza, Santos, Noélia Gonçalves dos, Mecca Junior, Sérgio Vitor, Neves, Júlio Leal Bandeira, Fernandes, André Maurício Souza, Aras Júnior, Roque, Reis, Francisco José Farias Borges dos, Guimarães, Armênio Costa, and Carvalho, Vitor Oliveira
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Rehabilitation ,Heart failure ,Exercise ,Physiotherapy ,Neuromuscular electrostimulation - Abstract
p. 1-5 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-05-06T17:11:54Z No. of bitstreams: 1 Roque Aras Junior.pdf: 437009 bytes, checksum: 0228c61154c7cbb5a4812096acd4fe57 (MD5) Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-10-19T12:50:33Z (GMT) No. of bitstreams: 1 Roque Aras Junior.pdf: 437009 bytes, checksum: 0228c61154c7cbb5a4812096acd4fe57 (MD5) Made available in DSpace on 2015-10-19T12:50:33Z (GMT). No. of bitstreams: 1 Roque Aras Junior.pdf: 437009 bytes, checksum: 0228c61154c7cbb5a4812096acd4fe57 (MD5) Previous issue date: 2012 Background: Neuromuscular electrostimulation has become a promising issue in cardiovascular rehabilitation. However there are few articles published in the literature regarding neuromuscular electrostimulation in patients with heart failure during hospital stay. Methods: This is a randomized controlled pilot trial that aimed to investigate the effect of neuromuscular electrostimulation in the walked distance by the six-minute walking test in 30 patients admitted to ward for heart failure treatment in a tertiary cardiology hospital. Patients in the intervention group performed a conventional rehabilitation and neuromuscular electrostimulation. Patients underwent 60 minutes of electrostimulation (wave frequency was 20 Hz, pulse duration of 20 us) two times a day for consecutive days until hospital discharge. Results: The walked distance in the six-minute walking test improved 75% in the electrostimulation group (from 379.7 ± 43.5 to 372.9 ± 46.9 meters to controls and from 372.9 ± 62.4 to 500 ± 68 meters to electrostimulation, p
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- 2012
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26. Journal of cardiothoracic surgery
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Pinheiro, Areli Cunha, Novais, Michelli Christina Magalhães, Gomes Neto, Mansueto, Rodrigues, Marcus Vinicius Herbst, Rodrigues Junior, Erenaldo de Souza, Aras Júnior, Roque, and Carvalho, Vitor Oliveira
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Assessment Vital Capacity ,Cardiac surgery ,Exercise ,physiotherapy - Abstract
Acesso restrito: Texto completo. Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-02-13T16:33:03Z No. of bitstreams: 1 C__Documents and Settings_rep...t.default_Cache_7_5A›A0d01.pdf: 436831 bytes, checksum: d01fbdecf4959861b244a23ccde0bf09 (MD5) Made available in DSpace on 2012-02-13T16:33:03Z (GMT). No. of bitstreams: 1 C__Documents and Settings_rep...t.default_Cache_7_5A›A0d01.pdf: 436831 bytes, checksum: d01fbdecf4959861b244a23ccde0bf09 (MD5) Previous issue date: 2011-05 Background: Measurement of vital capacity (VC) by spirometry is the most widely used technique for lung function evaluation, however, this form of assessment is costly and further investigation of other reliable methods at lower cost is necessary. Objective: To analyze the correlation between direct vital capacity measured with ventilometer and with incentive inspirometer in patients in pre and post cardiac surgery. Methodology: Cross-sectional comparative study with patients undergoing cardiac surgery. Respiratory parameters were evaluated through the measurement of VC performed by ventilometer and inspirometer. To analyze data normality the Kolmogorov-Smirnov test was applied, for correlation the Pearson correlation coefficient was used and for comparison of variables in pre and post operative period Student’s t test was adopted. We established a level of ignificance of 5%. Data was presented as an average, standard deviation and relative frequency when needed. The significance level was set at 5%. Results: We studied 52 patients undergoing cardiac surgery, 20 patients in preoperative with VC-ventilometer:32.95 ± 11.4 ml/kg and VC-inspirometer: 28.9 ± 11 ml/Kg, r = 0.7 p < 0.001. In the post operatory, 32 patients were evaluated with VC-ventilometer: 28.27 ± 12.48 ml/kg and VC-inspirometer: 26.98 ± 11 ml/Kg, r = 0.95 p < 0.001. Presenting a very high correlation between the evaluation forms studied. Conclusion: There was a high correlation between DVC measures with ventilometer and incentive spirometer in pre and post CABG surgery. Despite this, arises the necessity of further studies to evaluate the repercussion of this method in lowering costs at hospitals.
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- 2011
27. Jornal Brasileiro de Patologia e Medicina Laboratorial
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Aras Júnior, Roque, Vieira, Eder Andrade, Carvalho, Wilson Andrade de, Couto, Fábio David, and Couto, Ricardo David
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Proteína C reativa de alta sensibilidade ,Doença arterial coronária ,Estimativas de risco - Abstract
p. 113-118 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-02T17:18:33Z No. of bitstreams: 1 Roque Aras Júnior.pdf: 178703 bytes, checksum: 211f8c23e61f170756ae4cb2f1c9b222 (MD5) Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2015-10-09T18:48:31Z (GMT) No. of bitstreams: 1 Roque Aras Júnior.pdf: 178703 bytes, checksum: 211f8c23e61f170756ae4cb2f1c9b222 (MD5) Made available in DSpace on 2015-10-09T18:48:31Z (GMT). No. of bitstreams: 1 Roque Aras Júnior.pdf: 178703 bytes, checksum: 211f8c23e61f170756ae4cb2f1c9b222 (MD5) Previous issue date: 2011 INTRODUÇÃO: Índices calculados a partir de medidas laboratoriais e a determinação de marcadores plasmáticos são frequentemente utilizados para a avaliação do risco cardiovascular. OBJETIVO: Utilizar a razão triglicérides/colesterol da lipoproteína de alta densidade (HDL-C), estimativa de tamanho de partículas de lipoproteína de baixa densidade (LDL) e os níveis da proteína C reativa de alta sensibilidade (PCR-as) para a avaliação clínica e laboratorial do risco cardiovascular de pacientes com doença arterial coronariana (DAC). MATERIAL E MÉTODOS: Foram selecionados 60 pacientes por conveniência, 36 do sexo feminino (F) (65 ± 9 anos) e 24 do sexo masculino (M) (55 ± 10 anos) com diagnóstico de cardiopatia isquêmica estável, atendidos no Hospital Ana Neri, em Salvador, Bahia. A investigação foi realizada no Laboratório de Bioquímica Clínica da Faculdade de Farmácia da Universidade Federal da Bahia (UFBA). Amostras de sangue foram coletadas após 12 horas de jejum para determinação da PCR-as, do perfil lipídico e do cálculo de indicadores de risco. As determinações foram realizadas no equipamento Syncron LX®20 Beckman Coulter, USA. Foram considerados significativos os resultados da análise inferencial para p < 5%. A análise dos dados foi realizada no software GraphPad Prism®, versão 4.03. RESULTADOS: A análise dos dados mostrou correlação positiva entre a PCR-as e a razão triglicérides/HDL-C apenas para o sexo feminino (r = 0,4; p = 0,0442), n = 36. A análise dos demais parâmetros não mostrou significância. CONCLUSÃO: A razão triglicérides/HDL-C e a PCR-as podem ser utilizadas como indicadores do aumento do risco cardiovascular em mulheres com DAC.
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- 2011
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28. Therapeutic Adherence and Functional Capacity in Heart Failure
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Oliveira, Márcia Maria Carneiro, primary, Sampaio, Elieusa e Silva, additional, and Aras Júnior, Roque, additional
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- 2015
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29. Arq. Bras. Cardiol
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Mota, Gildo, Prazeres, Juliana, Freitas, Nelmacy, Magalhães, Luiz, Reis, Francisco, and Aras Júnior, Roque
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Chagas disease ,Left ,Pacemaker artificial ,Implanted ,Ventricular dysfunction ,Electrodes - Abstract
p.e122-e124 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-06-21T12:06:06Z No. of bitstreams: 1 Mota, Gildo.pdf: 417002 bytes, checksum: 0490efd43e4ec642c4595b37c587f618 (MD5) Made available in DSpace on 2012-06-21T12:06:06Z (GMT). No. of bitstreams: 1 Mota, Gildo.pdf: 417002 bytes, checksum: 0490efd43e4ec642c4595b37c587f618 (MD5) Previous issue date: 2010 The present case reports on a patient presenting the cardiac form of Chagas disease, with left ventricular dysfunction and second-degree atrioventricular block Mobitz type II, associated with several syncope episodes. The patient underwent a double-chamber definitive artificial pacemaker implant. One year after the implant, the displacement of the atrial electrode was diagnosed and the patient was submitted to re-implantation of the atrial electrode. Two years after the first surgical procedure, the patient presented dyspnea on exertion. The physical evaluation included an echocardiogram, which detected the presence of a foreign body with metallic characteristics in the left cardiac chambers, consistent with that of an ectopic pacemaker electrode. Rio de Janeiro
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- 2010
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30. PLoS Neglected Tropical Diseases
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Bastos, Claudilson Jose de Carvalho, Aras Júnior, Roque, Mota, Gildo, Reis, Francisco, Dias, Juarez Pereira, Jesus, Robson Silva de, Freire, Miralba Silva, Araújo, Eline Gomes de, Prazeres, Juliana, and Grassi, Maria Fernanda Rios
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Chagas Cardiomyopathy ,Mortality Rate ,Trypanosoma cruzi ,Chagas Disease - Abstract
p. 1-6 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-08-28T12:39:07Z No. of bitstreams: 1 pntd.0000711-1.pdf: 871705 bytes, checksum: 1cbb85d22a1b922097ab31ddf49fc584 (MD5) Approved for entry into archive by Flávia Ferreira(flaviaccf@yahoo.com.br) on 2013-08-28T17:28:17Z (GMT) No. of bitstreams: 1 pntd.0000711-1.pdf: 871705 bytes, checksum: 1cbb85d22a1b922097ab31ddf49fc584 (MD5) Made available in DSpace on 2013-08-28T17:28:17Z (GMT). No. of bitstreams: 1 pntd.0000711-1.pdf: 871705 bytes, checksum: 1cbb85d22a1b922097ab31ddf49fc584 (MD5) Previous issue date: 2010 Background: Outbreaks of orally transmitted Trypanosoma cruzi continue to be reported in Brazil and are associated with a high mortality rate, mainly due to myocarditis. Methods: This study is a detailed report on the disease progression of acute Chagas disease in 13 patients who were infected during two micro-outbreaks in two northeastern Brazilian towns. Clinical outcomes as well as EKG and ECHO results are described, both before and after benznidazole treatment. Results: Fever and dyspnea were the most frequent symptoms observed. Other clinical findings included myalgia, periorbital edema, headache and systolic murmur. Two patients died of cardiac failure before receiving benznidazole treatment. EKG and ECHO findings frequently showed a disturbance in ventricular repolarization and pericardial effusion. Ventricular dysfunction (ejection fraction
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- 2010
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31. Prevalencia de anemia e insuficiencia renal en portadores de insuficiencia cardiaca no hospitalizados
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Reis, Francisco José Farias Borges dos, Fernandes, André Maurício Souza, Bitencourt, Almir Galvão Vieira, Neves, Flávia Branco Cerqueira Serra, Kuwano, André Yoichi, França, Victor Hugo Pinheiro, Macedo, Cristiano Ricardo Bastos de, Cruz, Cristiano Gonçalves da, Sahade, Viviane, and Aras Júnior, Roque
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insuficiencia renal ,Insuficiência cardíaca ,insuficiência renal ,Heart failure ,urologic and male genital diseases ,anemia ,renal insufficiency ,Insuficiencia cardiaca - Abstract
FUNDAMENTOS: Insuficiência cardíaca (IC) é uma doença comum com alta taxa de mortalidade. Anemia e insuficiência renal (IR) são frequentemente encontradas em portadores de IC associadas com maior gravidade da doença cardíaca e pior prognóstico. OBJETIVO: Avaliar a prevalência de anemia e insuficiência renal, bem como a associação entre esses dois quadros, em portadores de IC não hospitalizados. MÉTODOS: Foram observados pacientes acompanhandos na clínica de IC de um hospital universitário de julho de 2003 a novembro de 2006. Anemia foi definida como níveis de hemoglobina abaixo de 13 mg/dl para homens e de 12 mg/dl para mulheres. A função renal foi avaliada por meio da taxa de filtração glomerular (TFG), calculada pela fórmula simplificada do estudo MDRD (Modification of Diet in Renal Disease). RESULTADOS: Dos trezentos e quarenta e cinco pacientes incluídos neste estudo, 26,4% (n = 91) tinham anemia e 29,6% tinham insuficiência renal moderada a grave (TFG < 60 ml/min). A associação entre anemia e maior prevalência de insuficiência renal foi estatisticamente significante (41,8% vs. 25,2%; p = 0,005). Os pacientes em classe funcional III e IV apresentaram maior incidência de anemia (39,0% vs. 19,4%; p
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- 2009
32. Arq. Bras. Cardiol
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Reis, Francisco José Farias Borges dos, Fernandes, André Maurício Souza, Bitencourt, Almir Galvão Vieira, Neves, Flávia Branco Cerqueira Serra, Kuwano, André Yoichi, França, Victor Hugo Pinheiro, Macedo, Cristiano Ricardo Bastos de, Cruz, Cristiano Gonçalves da, Sahade, Viviane, and Aras Júnior, Roque
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Heart failure ,Anemia ,Renal insufficiency - Abstract
p.249-254 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-06-21T12:48:41Z No. of bitstreams: 1 Reis, Francisco José Farias Borges dos.pdf: 486859 bytes, checksum: 9ba08b4e18dac6831ae35a77f0f87268 (MD5) Made available in DSpace on 2012-06-21T12:48:41Z (GMT). No. of bitstreams: 1 Reis, Francisco José Farias Borges dos.pdf: 486859 bytes, checksum: 9ba08b4e18dac6831ae35a77f0f87268 (MD5) Previous issue date: 2009 Background: Heart Failure (HF) is a common disease with a high rate of mortality. Anemia and renal failure (RF) are often found in patients with HF associated with higher severity of the heart disease and a worse prognosis. Objective: To evaluate the prevalence of anemia and RF, as well as the association between these two conditions, in non-hospitalized patients with HF. Methods: Patients treated at the HF Outpatient Clinic of a university hospital were followed from July 2003 to November 2006. Anemia was defined as hemoglobin levels < 13 mg/dl for men and 12 mg/dl for women. Renal function was assessed by the glomerular filtration rate (GFR), calculated by the simplified formula of the MDRD (Modification of Diet in Renal Disease) study. Results: Of the 345 patients included in this study, 26.4% (n = 91) had anemia and 29.6% had moderate to severe renal failure (GFR < 60 ml/min). The association between anemia and a higher prevalence of renal failure was statistically significant (41.8% vs. 25.2%; p = 0.005). The patients at functional class III and IV presented a higher incidence of anemia (39.0% vs. 19.4%; p
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- 2009
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33. Arq Neuropsiquiatr
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Magalhães, Manuela Oliveira de Cerqueira, Peixoto, Josecy Maria de Souza, Frank, Mônica Hupsel, Gomes, Irênio, Rodrigues, Bernardo Mota, Menezes, Carla, Cardoso, Eduardo, Carvalho, Fernando, Aras Júnior, Roque, and Melo, Ailton de Souza
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Elderly ,Risk factors ,Prevalence ,Dementia ,Population aging - Abstract
p.157-162 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-05-15T18:57:28Z No. of bitstreams: 1 Magalhães, Manuela Oliveira de Cerqueira.pdf: 204873 bytes, checksum: cd08e66e9d1014d323f2c479551e834e (MD5) Made available in DSpace on 2012-05-15T18:57:28Z (GMT). No. of bitstreams: 1 Magalhães, Manuela Oliveira de Cerqueira.pdf: 204873 bytes, checksum: cd08e66e9d1014d323f2c479551e834e (MD5) Previous issue date: 2008-06 Objective: To identify risk factors for dementia among the elderly in a rural area of Northeastern Brazil. Method: The subjects assessed were all 60 years old or older, and lived in a rural region of Bahia, a Northeastern State of Brazil. CAMDEX, a structured clinical evaluation protocol, was used for diagnosis, and applied at the home of the subjects. Results: The risk factors identified were divided in accordance with socio-demographic characteristics, the presence of co-morbid conditions, and the use of medications. The variables with strong association with dementia were age, history of stroke, arterial hypertension, and sight impairment. Conclusion: Advanced age, arterial hypertension, and vascular brain injury were the main risk factors associated with dementia, which suggests that public health measures adopted to prevent and control modifiable risk factors can mitigate the prevalence of high rates of dementia. São Paulo
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- 2008
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34. International Journal of Cardiology
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Braga, Julio Cesar Vieira, Reis, Francisco, Aras Júnior, Roque, Dantas, Nei, Bitencourt, Almir Galvão Vieira, Neves, Flávia Branco Cerqueira Serra, and Latado, Adriana L.
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Educational status ,Congestive ,Heart failure ,Chagas cardiomyopathy ,Mortality - Abstract
Texto completo: acesso restrito. p. 276-278 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-12-09T13:16:26Z No. of bitstreams: 1 1-s2.0-S016752730700589X-main.pdf: 88341 bytes, checksum: a4b18ceeb5623c65463325bc9775ce3b (MD5) Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-01-08T16:44:22Z (GMT) No. of bitstreams: 1 1-s2.0-S016752730700589X-main.pdf: 88341 bytes, checksum: a4b18ceeb5623c65463325bc9775ce3b (MD5) Made available in DSpace on 2014-01-08T16:44:22Z (GMT). No. of bitstreams: 1 1-s2.0-S016752730700589X-main.pdf: 88341 bytes, checksum: a4b18ceeb5623c65463325bc9775ce3b (MD5) Previous issue date: 2008 Some studies showed increased mortality in chagasic patients but most of these studies did not perform statistical adjustments to socioeconomic variables. The main objective of this study was to investigate if there is an independent association between Chagas etiology and mortality in patients with heart failure and moderate to severe left ventricle systolic dysfunction. Stratified analysis by the variables associated to chagasic etiology and multivariate analysis through logistic regression were performed to evaluate the relationship between Chagas cardiomyopathy and one-year mortality. Among 417 patients initially evaluated, 191 had the inclusion criteria. The mortality was higher in patients with Chagas cardiomyopathy than in the patients with other etiologies (log rank test; p = 0.036). At one-year follow-up, the mortality in chagasic patients was 21.6% versus 10.6% in the remaining (relative risk = 2.03; 95% CI = 0.98–4.2; p = 0.05). At logistic regression, educational level was identified as a confounder variable of the association between Chagas cardiomyopathy and one-year mortality. This association was no more statistically significant after adjustment for educational level (odds ratio = 1.67; 95% CI = 0.63–4.41). In this study, Chagas cardiomyopathy was a marker of worse prognosis, but was not independently associated to increased one-year mortality in outpatients with heart failure and moderate to severe systolic dysfunction.
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- 2008
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35. Predictors of amputation above the knee in Brazilian health system
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Borges, Wagner Ramos, de Carvalho, Aquiles Tadashi Ywata, and Aras Junior, Roque
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- 2017
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36. Arq. Bras. Cardiol
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Braga, Julio Cesar Vieira, Reis, Francisco, Aras Júnior, Roque, Costa, Nei Dantas, Bastos, Claudilson Jose de Carvalho, Silva, Renata, Soares, Alana, Moura Júnior, Ademir, Ásfora, Silvana, and Latado, Adriana Lopes
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Epidemiology ,Heart failure ,Chagasic cardiomyopathy - Abstract
p.296-301 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-06-27T12:40:16Z No. of bitstreams: 1 Braga, Julio Cesar Vieira.pdf: 188350 bytes, checksum: 71baec57547215028980df7e0a713db5 (MD5) Made available in DSpace on 2012-06-27T12:40:16Z (GMT). No. of bitstreams: 1 Braga, Julio Cesar Vieira.pdf: 188350 bytes, checksum: 71baec57547215028980df7e0a713db5 (MD5) Previous issue date: 2006-04 OBJECTIVE Describe the clinical and therapeutic characteristics of patients with heart failure (HF) secondary to chronic chagasic cardiomyopathy and evaluate if these characteristics are different from those found in other etiologies. METHODS A prospective analysis of the patients treated between August 2003 and June 2004 at a HF referral outpatient clinic was conducted. RESULTS Three hundred and fi fty six patients diagnosed with HF were included in the study. Chagasic cardiomyopathy was the most common etiology (48% of the cases). Other etiologies included hypertensive cardiomyopathy in 19% of the patients, idiopathic dilated in 11% and ischemic in 9%. Patients with HF secondary to chagasic cardiomyopathy were more frequently from non-white ethnic groups (88 vs. 75%; p = 0.002), had a family history of Chagas disease (57 vs. 21%; p = 0.001), had the disease for a longer length of time (71 vs. 56 months; p = 0.034), had lower levels of education (4.4 ± 4.1 vs. 5.7 ± 4.2 years of study; p = 0.004), had a lower heart rate (69 ± 12 vs. 73 ± 13; p = 0.03) and a lower systolic blood pressure (121 ± 25 vs. 129 ± 28 mmHg; p = 0.006). There was also a higher incidence of the use of amiodarone (22 vs. 13%; p = 0.036) and artifi cial pacemakers (15 vs. 1%; p = 0.001). There was a lower usage of beta-blockers (39 vs. 59%; p = 0.001). CONCLUSION In this sample of HF outpatients, in a state with a high prevalence of Chagas disease, chagasic cardiomyopathy was the most common etiology and they presented some unique clinical and therapeutic characteristics in comparison to other heart failure patients. Rio de Janeiro
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- 2006
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37. CARDIAC MAGNETIC RESONANCE IN THE EVALUATION OF FIBROSIS IN CHAGAS’ DISEASE
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Evangelista Lima, Polyana, primary, Fernandes, André Maurício, additional, Menezes, Marta, additional, J. N. Câmara, Edmundo, additional, and Aras Júnior, Roque, additional
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- 2014
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38. Brazilian Journal of Infectious Diseases
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Aras Júnior, Roque, Bastos, Claudilson Jose de Carvalho, Mota, Gildo, Sodré, Fábio, Moreira, Agnaluce, Tavares, Armando, and Lima, José Carlos
- Abstract
p.358-359 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-09-21T18:31:03Z No. of bitstreams: 1 Aras, Roque.pdf: 12110 bytes, checksum: b01c9cc634fca26cef0f43cfcd5b2253 (MD5) Made available in DSpace on 2012-09-21T18:31:03Z (GMT). No. of bitstreams: 1 Aras, Roque.pdf: 12110 bytes, checksum: b01c9cc634fca26cef0f43cfcd5b2253 (MD5) Previous issue date: 2003-12 Salvador
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- 2003
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39. Arquivos Brasileiros de Cardiologia
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Aras Júnior, Roque, Matta, José Alberto Martins da, Mota, Gildo de Oliveira, Gomes, Irênio, and Melo, Ailton de Souza
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Chagas’ disease ,frequency ,autopsies ,cerebral infarction - Abstract
p.414-416 Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2011-12-12T12:27:10Z No. of bitstreams: 1 17729.pdf: 32446 bytes, checksum: 5e3b1a6fa0651c3cc3e876908c27d525 (MD5) Made available in DSpace on 2011-12-12T12:27:10Z (GMT). No. of bitstreams: 1 17729.pdf: 32446 bytes, checksum: 5e3b1a6fa0651c3cc3e876908c27d525 (MD5) Previous issue date: 2003 Objective – To determine the frequency of encephalic infarction and its contribution to lethality in patients with Chagas’ disease and heart failure. Methods – Medical records and autopsy reports of patients with Chagas’ disease complicated by heart failure, who died at the Professor Edgar Santos Hospital of the Federal University of Bahia in the past 45 years were retrospectively analyzed. Data comprised information regarding the clinical history on hospital admission, complementary and anatomicopathological examinations, including the presence of encephalic infarction, the impaired region, and the cause of death.Results – Of the 5,447 autopsies performed, 524 were in patients with heart failure due to Chagas’ disease. The mean age was 45.7 years, and 51 (63%) patients were of the male sex. The frequency of encephalic infarction was 17.5%, corresponding to 92 events in 92 individuals, 82 (15.8%) of which involved the brain, 8 (1.5%) involved the cerebellum, and 2 (0.4%) involved the hypophysis. Conclusion - Cerebral infarction has been a frequent finding in autopsies of chagasic patients with heart failure, and it has been an important cause of death in our region. The presence of cerebral infarction and its complications have been associated with death in 52% of the cases studied.
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- 2003
40. Revista da Sociedade Brasileira de Medicina Tropical
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Aras Júnior, Roque, Gomes, Irênio, Veiga, Marielza, and Melo, Ailton de Souza
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Chagas' disease ,Vectorial transmission ,Transmissão vetorial ,Trypanosoma cruzi ,Doença de Chagas ,Prevalência ,Prevalence - Abstract
P. 359-363,Mai-Jun. Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-09-09T19:21:53Z No. of bitstreams: 1 20298.pdf: 53939 bytes, checksum: 9a042a41d3ab84688caac1131ce3aa11 (MD5) Made available in DSpace on 2011-09-09T19:21:53Z (GMT). No. of bitstreams: 1 20298.pdf: 53939 bytes, checksum: 9a042a41d3ab84688caac1131ce3aa11 (MD5) Previous issue date: 2003 Após a realização de inquérito sorológico para determinar a prevalência de doença de Chagas no município, foram analisadas as variáveis: idade, sexo, história clínica e transfusional, grau de parentesco e sorologias, para a identificação da forma de transmissão da infecção. Foram analisados 863 munícipes. Identificamos 265 indivíduos cuja sorologia foi realizada também em suas respectivas mães. Destes, 232 apresentavam sorologia negativa para doença de Chagas e 33 (14,2%) foram positivos. Encontramos 9 (3,9%) filhos com transmissão vetorial (idade média de 14,3 anos) e 24 (10,3%) filhos com mães também positivas, com idade média de 26,6 anos. Quando comparamos os dois grupos em relação às médias de idade e ao modo de transmissão do Trypanosoma cruzi, encontramos diferença com significância estatística. Esta diferença poderia ser explicada pela instalação das medidas de controle ou interrupção temporária da transmissão. Os resultados sugerem que ainda existe transmissão vetorial ativa do Trypanosoma cruzi em Mulungu do Morro. Uberaba
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- 2003
41. Impact of aspirin use in the incidence of thromboembolic events after bioprosthesis replacement in patients with rheumatic disease
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Durães, André Rodrigues, primary, Durães, Milena Andrade Oliveira, additional, Correia, Luis Claudio, additional, Fernandes, André Mauricio Souza, additional, and Aras Júnior, Roque, additional
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- 2013
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42. Razão triglicérides/HDL-C e proteína C reativa de alta sensibilidade na avaliação do risco cardiovascular
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Vieira, Eder Andrade, primary, Carvalho, Wilson Andrade, additional, Aras Júnior, Roque, additional, Couto, Fábio David, additional, and Couto, Ricardo David, additional
- Published
- 2011
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43. Prevalência de anemia e insuficiência renal em portadores de insuficiência cardíaca não-hospitalizados
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Reis, Francisco José Farias Borges dos, primary, Fernandes, André Maurício Souza, additional, Bitencourt, Almir Galvão Vieira, additional, Neves, Flávia Branco Cerqueira Serra, additional, Kuwano, André Yoichi, additional, França, Victor Hugo Pinheiro, additional, Macedo, Cristiano Ricardo Bastos de, additional, Cruz, Cristiano Gonçalves da, additional, Sahade, Viviane, additional, and Aras Júnior, Roque, additional
- Published
- 2009
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44. Impact of socio-economic profile on the prosthesis type choice used on heart surgery.
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S. Fernandes, André Maurício, Santana Bitencourt, Larissa, Nogueira Lessa, Igor, Viana, Agnaldo, Pereira, Felipe, Bastos, Gabriel, Bastos de Macedo, Cristiano Ricardo, and Aras Júnior, Roque
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CORONARY heart disease surgery ,CARDIAC surgery patients ,ARTIFICIAL organs ,PUBLIC health ,PROSTHETICS ,ARTIFICIAL implants - Abstract
Copyright of Brazilian Journal of Cardiovascular Surgery is the property of Sociedade Brasileira de Cirurgia Cardiovascular and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2012
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45. Infarto Cerebral Em Pacientes Com Insuficiência Cardíaca: Características Associadas E Função Atrial Esquerda
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Oliveira, Márcia Maria Carneiro, Aras Júnior, Roque, Braga, Adriana Lopes Latado, Sampaio, Elieusa e Silva, Câmara, Edmundo José Nassri, Fernandes, André Maurício de Souza, and Hatem, Maria Amélia Bulhões
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Insuficiência Cardíaca ,Acidente Vascular Cerebral ,Disfunção Ventricular Esquerda - Abstract
Submitted by Pos-Graduação Medicina e Saúde (ppgms@ufba.br) on 2019-03-13T13:37:34Z No. of bitstreams: 1 OLIVEIRA, MMC-2018.pdf: 1999496 bytes, checksum: 8191f03bfe8c55de55d87135cdfb4ece (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2019-04-02T16:18:13Z (GMT) No. of bitstreams: 1 OLIVEIRA, MMC-2018.pdf: 1999496 bytes, checksum: 8191f03bfe8c55de55d87135cdfb4ece (MD5) Made available in DSpace on 2019-04-02T16:18:19Z (GMT). No. of bitstreams: 1 OLIVEIRA, MMC-2018.pdf: 1999496 bytes, checksum: 8191f03bfe8c55de55d87135cdfb4ece (MD5) Introdução: A Insuficiência Cardíaca (IC) predispõe um risco aumentado de eventos cardioembólicos, dentre eles o infarto cerebral silencioso e o infarto cerebral embólico. O desfecho primário da tese é avaliar os fatores associados com infarto cerebral em pacientes com IC e os desfechos secundários são descrever as características clínicas e ecocardiográficas e os fatores associados com infarto cerebral silencioso em pacientes com IC de acordo com os grupos de fração de ejeção do ventrículo esquerdo (FEVE), descrever a relação da velocidade de fluxo do apêndice atrial esquerdo (AAE) com a formação de contraste ecogênico espontâneo (CEE)/trombos intracavitários e infarto cerebral embólico em pacientes com IC, revisar a literatura quanto à prevalência e fatores associados ao infarto cerebral silencioso e quanto a velocidade de fluxo/esvaziamento do apêndice atrial esquerdo como fator trombogênico. Métodos: Realizou-se um estudo de corte transversal, em um ambulatório de um hospital referência em cardiologia, entre dezembro/2015 e julho/2017 (Salvador/Brasil). O diagnóstico de infarto cerebral silencioso foi definido pela presença de infartos no parênquima encefálico (territorial ou lacunar) verificados através de métodos de imagem, sem episódio prévio de acidente vascular cerebral (AVC) documentado e sem história clínica. O infarto cerebral embólico foi definido como: cortical, territoriais e múltiplos, verificados através da tomografia de crânio. Os grupos da FEVE foram: FEVE reduzida (FEVEr) ≤ 40%, FEVE intermediária (FEVEi) 41-49% e FEVE preservada (FEVEp) ≥50%. Todos os pacientes realizaram tomografia de crânio, ecocardiograma transtorácico e ecocardiograma transesofágico. Resultados: No estudo com grupos de FEVE a amostra foi de 75 pacientes. Infarto cerebral silencioso foi observado em 14,7% da população do estudo (45,5% lacunar e 54,5% territorial) e mais frequentemente nos pacientes do grupo de FEVEr (29%) em comparação com a FEVEi (15,4%) (p=0,005). Não houve casos de infarto cerebral silencioso no grupo de FEVEp. Na análise bivariada identificou-se associação de infarto cerebral silencioso com FEVEr (Odds ratio (OR) = 8,6; Intervalo de confiança de 95%, 1,7- 43,3; P = 0,009) e diabetes mellitus (OR 4,3: Intervalo de confiança de 95%, 1,1-16,1; P=0,031). A velocidade de fluxo do AAE, foi estudada 49 pacientes com média de idade 59,9±10,8 anos. Infarto cerebral embólico foi detectado em 30,6% da amostra e 16,3 % tinham CEE/trombos intracavitários. A curva ROC associou a velocidade de fluxo do AAE com CEE/trombos intracavitários, com ponto de corte que determinou a presença de CEE/ trombos intracavitários quando a velocidade de fluxo do AAE ≤ 30cm/s (p=30cm/s (Grupo II: n=38). Na análise multivariada, em seu modelo final o preditor independente para velocidade de fluxo do AAE ≤ 30cm/s, foi a presença de CEE/trombos intracavitários (OR= 19,02; intervalo de confiança de 95%, 2,36-152,73; P= 0,006). Conclusões: Quanto menor a FEVE, maior a prevalência de infarto cerebral silencioso. O achado ecocardiográfico da velocidade de fluxo/esvaziamento do AAE baixa (≤30cm/s) está associado com a presença de CEE/trombos intracavitários com uma sensibilidade de 75% e especificidade de 85% (neste ponto de corte) indica que esta população de IC está em risco elevado de trombose.
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- 2018
46. Mortalidade em idosos de acordo com a presença de serpe e lesão renal aguda em unidade de terapia intensiva
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Rocha, Juliana Souza, Cruz, Constança Margarida Sampaio, Peixoto, Josecy Maria de Souza, Magalhães, Manuela Oliveira de Cerqueira, Oliveira, Eloina Nunes de, Aras Júnior, Roque, and Levi, Talita Machado
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Mortalidade. Lesão renal. Pacientes críticos. Sepse. Idosos e prognóstico - Abstract
a sepse é a principal causa de mortalidade em Unidade de Terapia Intensiva (UTI), estando frequentemente associada à lesão renal aguda (LRA). Estudos em países desenvolvidos indicam elevada mortalidade relacionada a esta associação, com maior susceptibilidade nas faixas etárias mais avançadas. Entretanto, em países em desenvolvimento, onde a epidemiologia da sepse e da LRA pode diferir substancialmente, os dados da literatura são escassos. Objetivo: determinar a mortalidade de idosos críticos com sepse precoce; investigar variáveis associadas com mortalidade em idosos críticos e verificar se há efeito modificador da LRA na mortalidade de idosos com sepse precoce. Métodos: um corte transversal aninhado a uma coorte em um UTI no Brasil, incluindo 167 pacientes idosos admitidos no período de Janeiro de 2010 a Janeiro de 2011. Dados clínicos-demográficos e laboratoriais foram coletados diariamente desde admissão até óbito ou alta da UTI, sendo excluídos aqueles com diagnóstico de morte encefálica e portadores de insuficiência renal terminal. Sepse foi definida de acordo com as Diretrizes Internacionais de Sepse de 2012 e LRA pelo estágio Risk do RIFLE. As análises estatísticas foram realizadas no software SPSS® versão 17.0, testes do qui-quadrado para comparação de proporções, teste t de Student para comparação de médias e regressão multivariada para identificação de variáveis associadas à morte e ajuste para confundimento. Resultados: a mortalidade foi de 64,83% (IC95% 54,59-73,88) entre idosos sépticos (≥ 60 anos) e 69,23% (IC95% 59,33- 78,12) considerando ponto de corte de países desenvolvidos (idoso≥ 65 anos). As variáveis associadas com óbito foram: necessidade de ventilação mecânica, sepse, cirurgia de emergência, procedência de enfermarias e LRA. A diferença das razões de prevalência de mortalidade entre portadores de LRA superposta a sepse e sepse apenas foi de 37,55%. Conclusão: prevalência de óbitos em idosos sépticos foi bastante elevada, aumentando sobremaneira quando associado à LRA, necessidade de ventilação mecânica e procedência de enfermarias clínicas.
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- 2018
47. Episódios De Alta Frequência Atrial E Sua Associação Com Eventos Isquêmicos Cerebrais Em Pacientes Chagásicos
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Freitas, Emanoela Lima, Aras Júnior, Roque, Durães, André Rodrigues, Silva, Elieusa Sampaio e, and Lima Filho, José Admirço
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Infarto cerebral ,Marcapasso artificial ,Doença de Chagas ,Fibrilação atrial - Abstract
Submitted by Pos-Graduação Medicina e Saúde (ppgms@ufba.br) on 2019-03-13T16:57:10Z No. of bitstreams: 1 FREITAS EL-2018.pdf: 1265855 bytes, checksum: 1f8c3c83205acec75b85a239d366ec54 (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2019-03-18T14:45:07Z (GMT) No. of bitstreams: 1 FREITAS EL-2018.pdf: 1265855 bytes, checksum: 1f8c3c83205acec75b85a239d366ec54 (MD5) Made available in DSpace on 2019-03-18T14:45:07Z (GMT). No. of bitstreams: 1 FREITAS EL-2018.pdf: 1265855 bytes, checksum: 1f8c3c83205acec75b85a239d366ec54 (MD5) Introdução: Dispositivos cardíacos eletrônicos implantáveis (DCEIs), permitem o monitoramento contínuo do ritmo atrial, e através dessa tecnologia, pacientes com episódios de alta frequência atrial (EAFAs), podem ser identificados. Um crescente número de dados clínicos suporta a hipótese de que os EAFAs ≥ 6 minutos estão associados a um risco elevado de eventos isquêmicos cerebrais e de desenvolvimento de fibrilação atrial (FA) clínica, porém o nível de limiar dos EAFAs que justifica a anticoagulação oral não está claro. Pacientes chagásicos apresentam maior risco de desenvolvimento de arritmias atriais e suas complicações tromboembólicas. Nesta população, até o momento não há, na literatura, dados relacionados à investigação da presença de EAFAs ≥ 6 minutos e sua incidência/prevalência, bem como sua associação com eventos isquêmicos cerebrais, pois não foram desenvolvidas pesquisas voltadas a avaliação destes pacientes. Objetivos: Investigar se existe associação entre a presença de EAFAs ≥ 6 minutos e eventos isquêmicos cerebrais através de tomografia computadorizada (TC) de crânio. Métodos: Estudo de coorte, onde foram incluídos pacientes chagásicos, portadores de DCEIs, acompanhados no Ambulatório de arritmias de um Hospital Universitário, na cidade de Salvador-Bahia-Brasil, entre maio de 2016 e junho de 2017. Pacientes com diagnóstico de flutter atrial / fibrilação atrial permanente, com DCEI unicameral e em uso de anticoagulação oral foram excluídos. Para análise, foram considerados EAFAs com frequência atrial ≥ 190 batimentos por minuto (bpm) e duração ≥ 6 minutos (min) detectados através dos DCEIs e eventos isquêmicos cerebrais identificados através de tomografia computadorizada (TC) de crânio. Resultados: Os 67 participantes da pesquisa (67,2% do sexo feminino, com idade média de 63,6 ± 9,2 anos) foram acompanhados por 98 ± 28,8 dias. Os EAFAs ≥ 6 min foram identificados em 11,9% da população. A TC de crânio evidenciou presença de eventos isquêmicos cerebrais silenciosos em 16,4% dos pacientes, sendo que destes, 63,6% havia apresentado os EAFAs ≥ 6 min na análise do dispositivo cardíaco. A presença de tais episódios atriais foi associada a ocorrência de eventos isquêmicos cerebrais [OR 96,2 (9,4-987,4; p
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- 2018
48. Avaliação da fração de ejeção reduzida na ocorrência de acidente vascular cerebral em pacientes com insuficiência cardíaca
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Sampaio, Eliusa e Silva, Aras Júnior, Roque, Braga, Adriana Lopes Latado, D’Oliveira Júnior, Argemiro, Machado, Carolina Souza, Martins Netto, Eduardo, and Reis, Francisco José Farias Borges dos
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Insuficiência Cardíaca ,Acidente Vascular Cerebral ,Disfunção Ventricular Esquerda - Abstract
Submitted by Pos-Graduação Medicina e Saúde (ppgms@ufba.br) on 2019-03-12T12:50:29Z No. of bitstreams: 1 TESE REVISADA 14 12 2017.pdf: 1887788 bytes, checksum: 2c1da5afe124ded9198e4adea4d62b67 (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2019-04-01T16:48:01Z (GMT) No. of bitstreams: 1 TESE REVISADA 14 12 2017.pdf: 1887788 bytes, checksum: 2c1da5afe124ded9198e4adea4d62b67 (MD5) Made available in DSpace on 2019-04-01T16:48:01Z (GMT). No. of bitstreams: 1 TESE REVISADA 14 12 2017.pdf: 1887788 bytes, checksum: 2c1da5afe124ded9198e4adea4d62b67 (MD5) Introdução: A fração de ejeção do ventrículo esquerdo (FEVE) é usada para avaliar a função sistólica do ventrículo esquerdo e a sua complexa relação com Insuficiência Cardíaca (IC) e eventos embólicos ainda é controversa, pois ainda não é claro o impacto da FEVE na maior ocorrência de Acidente Vascular Cerebral (AVC). Em relação à Doença de Chagas (DC), esta é um fator de risco bem definido para AVC, mas o significado prognóstico da prevalência de AVC na FEVE reduzida em comparação com a FEVE preservada em pacientes com IC e DC, ainda é pouco conhecido. O objetivo primário da tese é avaliar a associação de AVC com FEVE reduzida em pacientes com IC e os objetivos secundários são avaliar a associação de AVC com FEVE reduzida em pacientes com doença de Chagas e revisar a literatura quanto à associação do AVC e FEVE. Métodos: Pacientes com IC (n = 151) foram incluídos de um ambulatório de Miocardiopatias de um hospital universitário. A FEVE foi medida e obtida pelo ecocardiograma. Foram comparados grupos de pacientes com IC com FEVE > 39% e FEVE ≤ 39%. Todos os pacientes realizaram tomografia computadorizada (TC) de crânio. No estudo com pacientes com doença de Chagas cardíaca, a amostra foi de 85 pacientes e os grupos foram comparados com a FEVE ≤ 40% e FEVE >40%, para avaliar a ocorrência de AVC em pacientes com DC e FEVE reduzida. Resultados: Oitenta e dois pacientes tinham FEVE > 39% e 69 FEVE ≤ 39%. A prevalência de AVC foi de 53% na amostra. O AVC foi detectado em 68,1% dos pacientes com FEVE ≤ 39% (OR: 3,17; IC 95%: 1,62-6,21) comparado a 40,2% dos pacientes com FEVE > 39%. A análise multivariada revelou que a FEVE ≤ 39% (OR: 3,65; IC 95%: 1,71-7,79), idade ≥ 60 anos (OR: 2,69; IC 95%: 1,27-5,71), fibrilação atrial (OR: 5,60; 95 % CI: 1,71-18,31), dislipidemia (OR: 2,18; IC 95%: 1,01-4,70) e doença cardíaca isquêmica (OR: 2,77; IC 95%: 1,10 -6,10) foram independentemente associados com a ocorrência de AVC. Nos pacientes chagásicos, evidenciou-se que a FEVE ≤ 40% (OR 4,37: 1,65- 11,63; p= 0,) foi um associado a AVC em comparação com pacientes com FEVE preservada. Observou-se ainda uma alta prevalência (50%) de AVC nesta população. Além disso, foram detectados uma alta frequência de AVCs silenciosos nas populações estudadas. Conclusões: Os dados sugerem que a FEVE reduzida foi associada à elevada frequência de AVC em pacientes com IC e em pacientes chagásicos.
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- 2017
49. Terapia de expansão pulmonar na oxigenação arterial e no nível serico de lactato no pós operatório imediato de cirurgia cardíaca
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Oliveira, Silvana Souza, Aras Júnior, Roque, Gomes Neto, Mansueto, Dias, Cristiane Maria Carvalho Costa, Martinez, Bruno Prata, and Durans, André Rodrigues
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Nível de Oxigênio ,Cirurgia Torácica ,Medicina e Saúde ,Modalidades de Fisioterapia ,L-Lactato Desidrogenase - Abstract
Submitted by Pos-Graduação Medicina e Saúde (ppgms@ufba.br) on 2017-09-08T13:47:13Z No. of bitstreams: 1 DISSERTAÇÃO-SILVANA SOUZA OLIVEIRA.pdf: 1010358 bytes, checksum: 4a914badc6ed4bbd3bf96fdf360d23c2 (MD5) Approved for entry into archive by Edvaldo Souza (edvaldosouza@ufba.br) on 2017-10-02T17:48:09Z (GMT) No. of bitstreams: 1 DISSERTAÇÃO-SILVANA SOUZA OLIVEIRA.pdf: 1010358 bytes, checksum: 4a914badc6ed4bbd3bf96fdf360d23c2 (MD5) Made available in DSpace on 2017-10-02T17:48:10Z (GMT). No. of bitstreams: 1 DISSERTAÇÃO-SILVANA SOUZA OLIVEIRA.pdf: 1010358 bytes, checksum: 4a914badc6ed4bbd3bf96fdf360d23c2 (MD5) RESUMO Fundamentos: Complicações cardiovasculares e pulmonares ocorrem com frequência no período pós-operatório imediato e podem ser prevenidas e/ou tratadas através da utilização de técnicas de expansão pulmonar. Objetivo: Avaliar os efeitos das técnicas de expansão pulmonar nos níveis séricos de lactato arterial e oxigenação de pacientes no pós-operatório imediato de cirurgia cardíaca. Método: Estudo submetido e aprovado pelo Comitê de Ética do Hospital Ana Neri via Plataforma Brasil, CAEE: 38276614.0.0000.0045 no ano de 2014. Foi realizado em estudo quasi experimental, prospectivo e analítico em pacientes no pós-operatório de cirurgia cardíaca, estáveis hemodinamicamente e que necessitaram de acordo com a sua evolução clínica e condição respiratória da aplicação de técnicas de terapia de expansão pulmonar, como manobra de recrutamento alveolar e respiração por pressão positiva intermitente. A coleta de sangue para a realização da hemogasometria foi realizada quinze minutos antes e depois da aplicação de uma dessas técnicas com a finalidade de medir a variação do nível de lactato arterial, da oxigenação e saturação periférica de oxigênio. Resultados: Foram incluídos 40 pacientes com idade média de 51,1±14,9 anos, 55% eram do sexo feminino e com fração de ejeção do ventrículo esquerdo de 59,6±9,7. Pode-se observar diferença estatisticamente significativa (p
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- 2016
50. Intervenção educacional à adesão terapêutica na insuficiência cardíaca congestiva: aspectos clínicos, laboratoriais e funcionais
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Oliveira, Márcia Maria Carneiro, Aras Júnior, Roque Aras, Durães, André Ridrigues, Latado, Adriana Lopes, and Couto, Ricardo David
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Adesão à medicação ,Insuficiência cardiáca ,Medicina e Saúde ,Educação em sáude - Abstract
Submitted by Pos-Graduação Medicina e Saúde (ppgms@ufba.br) on 2017-08-25T17:23:28Z No. of bitstreams: 1 Dissertacao Marcia Carneiro.pdf: 2038064 bytes, checksum: f7b6fd3b637aac04218795e18c0f40d5 (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2017-08-28T14:00:45Z (GMT) No. of bitstreams: 1 Dissertacao Marcia Carneiro.pdf: 2038064 bytes, checksum: f7b6fd3b637aac04218795e18c0f40d5 (MD5) Made available in DSpace on 2017-08-28T14:00:45Z (GMT). No. of bitstreams: 1 Dissertacao Marcia Carneiro.pdf: 2038064 bytes, checksum: f7b6fd3b637aac04218795e18c0f40d5 (MD5) Introdução: Um dos principais fatores que levam à descompensação na Insuficiência Cardíaca (IC) é a baixa adesão dos pacientes ao tratamento. Programas de educação com intervenção educacional para o manejo da doença estão associados a uma melhor adesão. Objetivo: verificar se há associação entre adesão ao tratamento antes e após a intervenção educacional, avaliada por critérios clínicos, laboratoriais, funcionais e conhecimento em ambulatório especializado. Método: Ensaio clínico não controlado, com pacientes de IC e fração de ejeção do ventrículo esquerdo (FEVE) ≤ 40%. A adesão ao tratamento foi avaliada por questionário validado antes e após trinta dias de observação. Foi considerado desfecho primário o escore de adesão na IC e desfecho secundário a melhora clínica (classe funcional segundo a NYHA), laboratorial (uréia, creatinina, sódio, potássio e NT-proBNP), funcional pela distância percorrida no teste de caminhada de 6 min (TC6’) em pacientes com IC aderentes e não aderentes. Os dados apresentaram com distribuição não paramétrica. O nível de significância utilizado em todos os testes foi de 5% para o intervalo de confiança de 95%. Resultados: no período de dezembro de 2012 a julho de 2013, foram avaliados 80 pacientes. Destes, vinte e cinco pacientes foram incluídos. A mediana da idade foi de 52 anos e 56% eram do sexo masculino. Após um mês, houve melhora no escore de adesão (p= 0,006), perda de peso (p=0,022) e melhora do conhecimento (p=0,001). Quanto ao TC6’, observou-se um melhor desempenho nos pacientes aderentes, com faixa etária de 44 a 49 anos, cor de pele branca, classe funcional III, tempo de IC de 12 a 16 anos, FEVE reduzida e etiologia hipertensiva. Todos apresentaram melhora da função renal. NT-proBNP não se modificou significativamente. Conclusão: Observado melhora clínica e da função renal nos pacientes com IC ambulatoriais submetidos à intervenção educacional e que apresentaram maior adesão à terapêutica otimizada. A comparação de parâmetros funcionais como NT-proBNP e teste de caminhada não foram estatisticamente significantes. Palavras-chave: Insuficiência Cardíaca, adesão à medicação, educação em saúde, teste de caminhada de 6 minutos. Abstract Introduction: One of the main factors leading to decompensated heart failure (HF) is the low degree of patient adhesionto treatment. Educational programs with educational intervention for handling the illness is associated to improved adhesion. Objectives: Verify the association between treatment adhesion before and after educational intervention, evaluated by clinical, laboratory, functional criteria and knowledge. Methods: experimental, prospective, before and afterstudy conducted on HF patients with left ventricular ejection fraction (LVEF) ≤ 40%. Treatment adhesion was evaluated using a validated questionnaire before and after thirty days of observation. The primary considered outcome was an adhesion score of HF and secondary outcome was clinical improvement (functional class according to NYHA), laboratorial (urea, creatinine, sodium, potassium and NT-proBNP), functional for the covered distance by six minutes walking (6MWT) on adhering and non-adhering HF patients. Results: during the period from December 2012 to July 2013, 80 patients were evaluated. Of these, twenty-five patients were included. Average age was of 52 ±10 years, and 56% were of the male gender. After one month, there was an improvement in the adhesion score (p= 0.006), loss of weight (p=0.022) and improved awareness (p=0.001). In relation to the 6MWT, a better performance on adhering patients, age group 44-49 years, white spontaneous declared, functional class III, HF period from 12 to 16 years, reduced LVEF, from hypertensive etiology. NT-ProBNP did not alter significantly. Conclusion: clinical and renal function improvement wereobserved in HF outpatients submitted to educational interventions presenting higher adhesion to the optimal therapy. The comparison of functional parameters, such as NT-proBNP and 6MWT, were not statistically significant. Keywords: Heart failure, Medication adherence, health education, 6-minute walk test
- Published
- 2014
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