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Your search keyword '"Aranaz Novaliches, Goretti"' showing total 8 results
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8 results on '"Aranaz Novaliches, Goretti"'

1. Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease

Author

Gruper, Yael, Wolff, Anette S. B., Glanz, Liad, Spoutil, Frantisek, Marthinussen, Mihaela Cuida, Osickova, Adriana, Herzig, Yonatan, Goldfarb, Yael, Aranaz-Novaliches, Goretti, Dobeš, Jan, Kadouri, Noam, Ben-Nun, Osher, Binyamin, Amit, Lavi, Bar, Givony, Tal, Khalaila, Razi, Gome, Tom, Wald, Tomáš, Mrazkova, Blanka, Sochen, Carmel, Besnard, Marine, Ben-Dor, Shifra, Feldmesser, Ester, Orlova, Elisaveta M., Hegedűs, Csaba, Lampé, István, Papp, Tamás, Felszeghy, Szabolcs, Sedlacek, Radislav, Davidovich, Esti, Tal, Noa, Shouval, Dror S., Shamir, Raanan, Guillonneau, Carole, Szondy, Zsuzsa, Lundin, Knut E. A., Osicka, Radim, Prochazka, Jan, Husebye, Eystein S., and Abramson, Jakub

Published
2023
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4. Multi‐Level Approach for Comprehensive Enamel Phenotyping

Author

Aranaz‐Novaliches, Goretti, primary, Spoutil, Frantisek, additional, Bukova, Ivana, additional, Krejzova, Irena, additional, Olsinova, Marie, additional, Dalecka, Marketa, additional, Benda, Ales, additional, Rozman, Jan, additional, Sedlacek, Radislav, additional, and Prochazka, Jan, additional

Published
2022
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5. Cytoplasmic polyadenylation by TENT5A is required for proper bone formation

Author

Gewartowska, Olga, primary, Aranaz-Novaliches, Goretti, additional, Krawczyk, Paweł S., additional, Mroczek, Seweryn, additional, Kusio-Kobiałka, Monika, additional, Tarkowski, Bartosz, additional, Spoutil, Frantisek, additional, Benada, Oldrich, additional, Kofroňová, Olga, additional, Szwedziak, Piotr, additional, Cysewski, Dominik, additional, Gruchota, Jakub, additional, Szpila, Marcin, additional, Chlebowski, Aleksander, additional, Sedlacek, Radislav, additional, Prochazka, Jan, additional, and Dziembowski, Andrzej, additional

Published
2021
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6. Simple Sequence Repeat Allelic Diversity in Zoysiagrass Released from 1910 to 2016

Author

Mijangos Antón, Federico, F. CIENCIA Y TECNOLOGIA, ZIENTZIA ETA TEKNOLOGIA F., Grado en Biotecnología, Bioteknologiako Gradua, Aranaz Novaliches, Goretti, Mijangos Antón, Federico, F. CIENCIA Y TECNOLOGIA, ZIENTZIA ETA TEKNOLOGIA F., Grado en Biotecnología, Bioteknologiako Gradua, and Aranaz Novaliches, Goretti

Abstract

[EN] Z. japonica know as Zoysiagrass has been cultivated in China, Japan and Korea for centuries. 11 different species have been found to be part of Zoysiagrass but when it comes to commercial varieties Zoysia japonica Steud and Zoysia matrella (L.) Merr are mostly used in the United States for turfgrass purposes. Zoysiagrass has a relatively high heat and drought tolerance and has disease resistance. However, it could use more cold tolerance for colder weather places in the United States. Over the years, zoysiagrass cultivars have been improved using conventional breeding methods such as hybridization, clonal selection and mutagenesis. Subsequently, a better understanding of genetic diversity in Zoysiagrass would help improve breeding efforts. The purpose of this study is to analyze levels of genetic diversity at gene and population levels in 39 Zoysia cultivars (Zoysia spp. Willd.). 23 primer SSR markers were used to determine whether allelic diversity among these cultivars has change over a century of modern plant breeding. In this study, Zoysiagrass varieties analyzed were released between 1910 and 2016 and most of the samples were from North Carolina State University. The DNA was extracted from Zoysia cultivars and amplified with SSR markers using PCR. Then, the DNA was separated by size in polyacrylamide gel electrophoresis. Finally, all the results were analyzed. We evaluated genetic diversity at population level and conclude that allelic diversity declined during the 1990s but recovered during the 2000s. Our study demonstrates that the influence of science based plant breeding in Zoysiagrass has not been very successful because allelic diversity has decreased after reaching the peak in 2000s. In the future, the levels of genetic diversity should increase through future germplasm collections and the inclusion of less Zoysia species to create new hybrids. Additionally, SSR has proved to be useful to detect molecular variation in Zoysiagrass cultivars.

Published
2017

7. Simple Sequence Repeat Allelic Diversity in Zoysiagrass Released from 1910 to 2016

Author

Aranaz Novaliches, Goretti, Mijangos Antón, Federico, F. CIENCIA Y TECNOLOGIA, ZIENTZIA ETA TEKNOLOGIA F., Grado en Biotecnología, and Bioteknologiako Gradua

Subjects
SSR markers, zoysiagrass genetic diversity analysis, food and beverages, plant genetics
Abstract

[EN] Z. japonica know as Zoysiagrass has been cultivated in China, Japan and Korea for centuries. 11 different species have been found to be part of Zoysiagrass but when it comes to commercial varieties Zoysia japonica Steud and Zoysia matrella (L.) Merr are mostly used in the United States for turfgrass purposes. Zoysiagrass has a relatively high heat and drought tolerance and has disease resistance. However, it could use more cold tolerance for colder weather places in the United States. Over the years, zoysiagrass cultivars have been improved using conventional breeding methods such as hybridization, clonal selection and mutagenesis. Subsequently, a better understanding of genetic diversity in Zoysiagrass would help improve breeding efforts. The purpose of this study is to analyze levels of genetic diversity at gene and population levels in 39 Zoysia cultivars (Zoysia spp. Willd.). 23 primer SSR markers were used to determine whether allelic diversity among these cultivars has change over a century of modern plant breeding. In this study, Zoysiagrass varieties analyzed were released between 1910 and 2016 and most of the samples were from North Carolina State University. The DNA was extracted from Zoysia cultivars and amplified with SSR markers using PCR. Then, the DNA was separated by size in polyacrylamide gel electrophoresis. Finally, all the results were analyzed. We evaluated genetic diversity at population level and conclude that allelic diversity declined during the 1990s but recovered during the 2000s. Our study demonstrates that the influence of science based plant breeding in Zoysiagrass has not been very successful because allelic diversity has decreased after reaching the peak in 2000s. In the future, the levels of genetic diversity should increase through future germplasm collections and the inclusion of less Zoysia species to create new hybrids. Additionally, SSR has proved to be useful to detect molecular variation in Zoysiagrass cultivars.

Published
2016

8. Skeletal dysmorphology and mineralization defects in Fgf20 KO mice.

Author

Dlugosova S, Spoutil F, Madureira Trufen CE, Melike Ogan B, Prochazkova M, Fedosieieva O, Nickl P, Aranaz Novaliches G, Sedlacek R, and Prochazka J

Subjects
Animals, Mice, X-Ray Microtomography, Bone and Bones metabolism, Bone and Bones pathology, Bone and Bones diagnostic imaging, Bone and Bones abnormalities, Calcification, Physiologic, Male, Osteogenesis, Female, Mice, Inbred C57BL, Phenotype, Mice, Knockout, Fibroblast Growth Factors metabolism, Fibroblast Growth Factors genetics
Abstract

Introduction: Fibroblast growth factor 20 (Fgf20), a member of the Fgf9 subfamily, was identified as an important regulator of bone differentiation and homeostasis processes. However, the role of Fgf20 in bone physiology has not been approached yet. Here we present a comprehensive bone phenotype analysis of mice with functional ablation of Fgf20., Methods: The study conducts an extensive analysis of Fgf20 knockout mice compared to controls, incorporating microCT scanning, volumetric analysis, Fgf9 subfamily expression and stimulation experiment and histological evaluation., Results: The bone phenotype could be detected especially in the area of​ the lumbar and caudal part of the spine and in fingers. Regarding the spine, Fgf20 -/- mice exhibited adhesions of the transverse process of the sixth lumbar vertebra to the pelvis as well as malformations in the distal part of their tails. Preaxial polydactyly and polysyndactyly in varying degrees of severity were also detected. High resolution microCT analysis of distal femurs and the fourth lumbar vertebra showed significant differences in structure and mineralization in both cortical and trabecular bone. These findings were histologically validated and may be associated with the expression of Fgf20 in chondrocytes and their progenitors. Moreover, histological sections demonstrated increased bone tissue formation, disruption of Fgf20 -/- femur cartilage, and cellular-level alterations, particularly in osteoclasts. We also observed molar dysmorphology, including root taurodontism, and described variations in mineralization and dentin thickness., Discussion: Our analysis provides evidence that Fgf20, together with other members of the Fgf9 subfamily, plays a crucial regulatory role in skeletal development and bone homeostasis., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Dlugosova, Spoutil, Madureira Trufen, Melike Ogan, Prochazkova, Fedosieieva, Nickl, Aranaz Novaliches, Sedlacek and Prochazka.)

Published
2024
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